1     M         1.427   1.443   1.495   1.590   1.613   1.694   1.538   1.561   1.637
2     S        -0.008  -0.020  -0.274  -0.010  -0.032  -0.445  -0.023  -0.043  -0.406
3     Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     F        -0.974  -0.977  -0.891  -1.025  -1.054  -0.923  -0.966  -0.972  -0.851
6     V        -0.974  -0.739  -0.867  -1.018  -0.729  -0.845  -0.966  -0.692  -0.826
7     E         0.525   0.373   0.370   0.379   0.169   0.148   0.425   0.153   0.111
8     D        -0.974  -0.994  -0.896  -0.977  -1.021  -0.878  -0.966  -0.987  -0.856
9     Y        -0.974  -0.913  -0.870  -0.984  -0.958  -0.878  -0.966  -0.905  -0.829
10    S        -0.474  -0.458  -0.372  -0.523  -0.468  -0.339  -0.687  -0.656  -0.541
11    R        -0.974  -0.870  -0.860  -0.820  -0.662  -0.685  -0.966  -0.851  -0.819
12    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    D         0.748   0.855   0.484   0.729   0.863   0.354   0.778   0.930   0.320
33    E        -0.329  -0.204  -0.316  -0.591  -0.399  -0.564  -0.526  -0.367  -0.474
34    D        -0.835  -0.871  -0.860  -0.943  -0.991  -1.004  -0.852  -0.870  -0.821
35    S        -0.195  -0.225  -0.304  -0.383  -0.413  -0.587  -0.309  -0.333  -0.450
36    G        -0.329  -0.372  -0.347  -0.513  -0.546  -0.484  -0.526  -0.562  -0.514
37    A        -1.696  -1.607  -1.576  -1.594  -1.488  -1.388  -1.287  -1.209  -1.121
38    Y        -0.508  -0.678  -0.830  -0.197  -0.435  -0.676  -0.418  -0.621  -0.786
39    D        -0.953  -0.922  -0.843  -1.114  -1.046  -0.926  -0.961  -0.907  -0.802
40    E        -0.953  -0.945  -0.883  -1.174  -1.161  -1.029  -0.961  -0.946  -0.844
41    W         1.427   1.443   1.495   1.670   1.697   1.769   1.538   1.561   1.637
42    I         1.427   1.443   1.495   1.505   1.527   1.613   1.538   1.561   1.637
43    P        -0.953  -0.982  -0.880  -0.947  -1.001  -0.844  -0.961  -0.976  -0.841
44    S        -1.266  -1.268  -1.238  -1.044  -1.029  -0.952  -1.070  -1.059  -0.987
45    F         0.748   0.743   0.462   0.859   0.859   0.461   0.778   0.767   0.280
46    C         1.427   1.443   1.495   1.574   1.602   1.679   1.538   1.561   1.637
47    S         0.414   0.481   0.403   0.203   0.318   0.153   0.234   0.344   0.172
48    R        -0.329  -0.325  -0.340  -0.473  -0.481  -0.505  -0.526  -0.518  -0.508
49    F        -0.508  -0.678  -0.830  -0.301  -0.559  -0.820  -0.418  -0.621  -0.786
50    G         1.427   1.443   1.495   1.418   1.442   1.530   1.538   1.561   1.637
51    H         0.748   0.655   0.458   1.032   0.919   0.613   0.778   0.630   0.272
52    E         0.235   0.273   0.320  -0.151  -0.079  -0.015  -0.092  -0.032   0.016
53    Y         1.427   1.443   1.495   1.489   1.516   1.597   1.538   1.561   1.637
54    F         1.427   1.443   1.495   1.434   1.462   1.546   1.538   1.561   1.637
55    C        -0.329  -0.342  -0.341  -0.242  -0.231  -0.234  -0.526  -0.514  -0.502
56    Q        -0.329  -0.283  -0.343  -0.430  -0.416  -0.465  -0.526  -0.484  -0.511
57    V         1.427   1.443   1.495   1.521   1.552   1.628   1.538   1.561   1.637
58    P        -0.835  -0.872  -0.843  -0.889  -0.935  -0.871  -0.852  -0.871  -0.803
59    T        -0.523  -0.455  -0.374  -0.709  -0.631  -0.502  -0.744  -0.652  -0.544
60    E         0.414   0.414   0.335   0.251   0.250   0.050   0.234   0.226   0.044
61    F         1.427   1.443   1.495   1.434   1.462   1.546   1.538   1.561   1.637
62    I         1.427   1.443   1.495   1.505   1.527   1.613   1.538   1.561   1.637
63    E         1.427   1.443   1.495   1.236   1.274   1.358   1.538   1.561   1.637
64    D         1.427   1.443   1.495   1.370   1.399   1.485   1.538   1.561   1.637
65    D         0.748   0.655   0.458   0.764   0.643   0.320   0.778   0.630   0.272
66    F         1.427   1.443   1.495   1.434   1.462   1.546   1.538   1.561   1.637
67    N         1.427   1.443   1.495   1.528   1.563   1.635   1.538   1.561   1.637
68    M         0.414   0.537   0.412   0.281   0.454   0.286   0.234   0.439   0.189
69    T         1.427   1.443   1.495   1.510   1.538   1.617   1.538   1.561   1.637
70    S         0.414   0.537   0.412   0.325   0.520   0.293   0.234   0.439   0.189
71    L         1.427   1.443   1.495   1.280   1.305   1.400   1.538   1.561   1.637
72    S        -1.071  -1.150  -1.231  -0.826  -0.932  -1.003  -0.852  -0.936  -0.980
73    Q        -1.266  -1.298  -1.253  -1.145  -1.219  -1.186  -1.070  -1.091  -1.001
74    E        -0.835  -0.872  -0.843  -0.899  -0.904  -0.862  -0.852  -0.871  -0.803
75    V         1.427   1.443   1.495   1.521   1.552   1.628   1.538   1.561   1.637
76    P         0.414   0.392   0.327   0.419   0.377   0.256   0.234   0.187   0.030
77    H        -0.759  -0.821  -0.822  -0.524  -0.599  -0.608  -0.744  -0.791  -0.778
78    Y         1.427   1.443   1.495   1.489   1.516   1.597   1.538   1.561   1.637
79    R        -0.195  -0.317  -0.353  -0.063  -0.246  -0.311  -0.309  -0.475  -0.520
80    K         0.235   0.323   0.346  -0.085   0.068   0.096  -0.092   0.063   0.066
81    A         1.427   1.443   1.495   1.521   1.553   1.628   1.538   1.561   1.637
82    L         1.427   1.443   1.495   1.280   1.305   1.400   1.538   1.561   1.637
83    D        -0.447  -0.435  -0.375  -0.664  -0.667  -0.595  -0.635  -0.624  -0.546
84    L        -0.523  -0.516  -0.401  -0.664  -0.651  -0.469  -0.744  -0.731  -0.580
85    I         1.427   1.443   1.495   1.505   1.527   1.613   1.538   1.561   1.637
86    L         1.427   1.443   1.495   1.280   1.305   1.400   1.538   1.561   1.637
87    D         1.427   1.443   1.495   1.370   1.399   1.485   1.538   1.561   1.637
88    L        -0.759  -0.854  -0.844  -0.763  -0.879  -0.840  -0.744  -0.832  -0.803
89    E        -0.195  -0.225  -0.304  -0.293  -0.310  -0.414  -0.309  -0.333  -0.450
90    A        -1.383  -1.294  -1.252  -1.210  -1.108  -1.030  -1.179  -1.097  -1.001
91    M        -1.071  -0.968  -1.198  -0.939  -0.817  -1.077  -0.852  -0.748  -0.949
92    S        -0.396  -0.481  -0.388  -0.574  -0.716  -0.567  -0.587  -0.686  -0.564
93    D         0.280   0.316   0.339   0.100   0.153   0.187  -0.007   0.048   0.053
94    E         0.280   0.232   0.298  -0.118  -0.210  -0.096  -0.007  -0.109  -0.025
95    E         0.214   0.203   0.303  -0.245  -0.252  -0.075  -0.131  -0.164  -0.016
96    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
97    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
98    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
99    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
100   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
101   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
102   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
103   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
104   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
105   D         1.427   1.443   1.495   1.348   1.374   1.464   1.538   1.561   1.637
106   E         0.214   0.262   0.326  -0.124  -0.038   0.060  -0.131  -0.051   0.029
107   V        -1.473  -1.402  -1.287  -1.461  -1.414  -1.202  -1.244  -1.171  -1.028
108   D        -0.974  -0.867  -0.863  -1.174  -0.998  -1.028  -0.966  -0.841  -0.821
109   Q        -1.473  -1.402  -1.287  -1.293  -1.179  -1.043  -1.244  -1.171  -1.028
110   E        -0.974  -0.955  -0.870  -1.124  -1.123  -0.998  -0.966  -0.947  -0.829
111   M        -0.974  -0.941  -0.895  -0.852  -0.850  -0.762  -0.966  -0.933  -0.855
112   Q        -0.974  -0.941  -0.895  -1.150  -1.125  -1.048  -0.966  -0.933  -0.855
113   S        -0.474  -0.512  -0.397  -0.651  -0.719  -0.551  -0.687  -0.726  -0.575
114   N        -0.285  -0.339  -0.353  -0.237  -0.347  -0.416  -0.409  -0.498  -0.514
115   D        -1.473  -1.402  -1.287  -1.420  -1.299  -1.164  -1.244  -1.171  -1.028
116   G        -0.285  -0.360  -0.352  -0.310  -0.433  -0.444  -0.409  -0.524  -0.513
117   H        -0.969  -0.957  -0.891  -0.952  -0.949  -0.808  -0.973  -0.957  -0.852
118   D        -1.802  -1.721  -1.602  -1.658  -1.541  -1.390  -1.360  -1.286  -1.139
119   E        -0.974  -0.905  -0.867  -0.980  -0.833  -0.866  -0.966  -0.895  -0.826
120   G         0.214   0.303   0.346   0.070   0.208   0.275  -0.131   0.025   0.065
121   K        -1.473  -1.386  -1.287  -1.591  -1.494  -1.326  -1.244  -1.160  -1.028
122   R        -0.974  -0.894  -0.863  -0.968  -0.870  -0.836  -0.966  -0.878  -0.821
123   R        -0.474  -0.382  -0.370  -0.496  -0.372  -0.342  -0.687  -0.581  -0.542
124   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
125   N        -0.383  -0.402  -0.342  -0.415  -0.434  -0.328  -0.591  -0.601  -0.508
126   K        -1.723  -1.670  -1.567  -1.516  -1.453  -1.297  -1.300  -1.250  -1.114
127   S        -1.696  -1.619  -1.563  -1.672  -1.577  -1.465  -1.287  -1.217  -1.113
128   P        -1.266  -1.228  -1.249  -1.229  -1.174  -1.166  -1.070  -1.022  -0.997
129   V        -1.266  -1.315  -1.242  -1.132  -1.180  -1.040  -1.070  -1.102  -0.992
130   V        -0.835  -0.918  -0.864  -0.785  -0.906  -0.840  -0.852  -0.914  -0.825
131   N        -0.759  -0.781  -0.849  -0.636  -0.716  -0.817  -0.744  -0.785  -0.810
132   K        -1.266  -1.335  -1.250  -1.050  -1.155  -1.038  -1.070  -1.115  -0.997
133   S        -1.266  -1.242  -1.235  -1.185  -1.168  -1.135  -1.070  -1.038  -0.984
134   I        -0.953  -0.945  -0.883  -0.925  -0.909  -0.803  -0.961  -0.946  -0.844
135   I        -0.759  -0.689  -0.812  -0.669  -0.562  -0.748  -0.744  -0.655  -0.767
136   E        -0.195  -0.060  -0.271  -0.325  -0.131  -0.418  -0.309  -0.129  -0.403
137   H         0.101  -0.078  -0.281   0.440   0.193  -0.170   0.126  -0.121  -0.416
138   A         0.414   0.537   0.412   0.297   0.481   0.292   0.234   0.439   0.189
139   A         1.427   1.443   1.495   1.521   1.553   1.628   1.538   1.561   1.637
140   E         0.748   0.655   0.458   0.671   0.573   0.302   0.778   0.630   0.272
141   Q        -0.835  -0.918  -0.864  -0.796  -0.896  -0.790  -0.852  -0.914  -0.825
142   L         1.427   1.443   1.495   1.280   1.305   1.400   1.538   1.561   1.637
143   Y         1.427   1.443   1.495   1.489   1.516   1.597   1.538   1.561   1.637
144   G         1.427   1.443   1.495   1.418   1.442   1.530   1.538   1.561   1.637
145   L         1.427   1.443   1.495   1.280   1.305   1.400   1.538   1.561   1.637
146   I         1.427   1.443   1.495   1.505   1.527   1.613   1.538   1.561   1.637
147   H         1.427   1.443   1.495   1.606   1.635   1.709   1.538   1.561   1.637
148   A         0.414   0.320   0.327   0.500   0.349   0.331   0.234   0.057   0.029
149   R         1.427   1.443   1.495   1.505   1.528   1.613   1.538   1.561   1.637
150   F         0.178   0.203   0.297  -0.012   0.025   0.173  -0.200  -0.165  -0.028
151   I         0.748   0.743   0.462   0.900   0.891   0.451   0.778   0.767   0.280
152   L        -0.759  -0.809  -0.841  -0.738  -0.805  -0.796  -0.744  -0.799  -0.803
153   T         0.235   0.247   0.306   0.069   0.080   0.143  -0.092  -0.079  -0.011
154   K         0.414   0.320   0.327   0.452   0.293   0.277   0.234   0.057   0.029
155   P        -0.953  -0.938  -0.871  -0.863  -0.849  -0.729  -0.961  -0.945  -0.834
156   G         1.427   1.443   1.495   1.418   1.442   1.530   1.538   1.561   1.637
157   L         0.748   0.656   0.456   0.707   0.594   0.319   0.778   0.633   0.269
158   Q        -0.195  -0.225  -0.304   0.006  -0.014  -0.147  -0.309  -0.333  -0.450
159   A        -0.195  -0.280  -0.353  -0.028  -0.166  -0.270  -0.309  -0.444  -0.520
160   M         1.427   1.443   1.495   1.590   1.613   1.694   1.538   1.561   1.637
161   A         0.748   0.656   0.456   0.922   0.807   0.469   0.778   0.633   0.269
162   E        -0.195  -0.152  -0.296  -0.391  -0.305  -0.521  -0.309  -0.241  -0.438
163   K         1.427   1.443   1.495   1.489   1.519   1.597   1.538   1.561   1.637
164   F         0.235   0.210   0.297   0.090   0.038   0.174  -0.092  -0.150  -0.028
165   D        -0.329  -0.383  -0.345  -0.617  -0.693  -0.642  -0.526  -0.579  -0.513
166   H        -1.266  -1.325  -1.247  -1.052  -1.155  -1.079  -1.070  -1.104  -0.995
167   K        -0.953  -0.945  -0.883  -0.884  -0.884  -0.782  -0.961  -0.946  -0.844
168   E        -1.266  -1.338  -1.237  -1.250  -1.303  -1.144  -1.070  -1.118  -0.988
169   F         1.427   1.443   1.495   1.434   1.462   1.546   1.538   1.561   1.637
170   G         1.427   1.443   1.495   1.418   1.442   1.530   1.538   1.561   1.637
171   T        -0.759  -0.854  -0.844  -0.619  -0.735  -0.735  -0.744  -0.832  -0.803
172   C         1.427   1.443   1.495   1.574   1.602   1.679   1.538   1.561   1.637
173   P         1.427   1.443   1.495   1.449   1.470   1.559   1.538   1.561   1.637
174   R         1.427   1.443   1.495   1.505   1.528   1.613   1.538   1.561   1.637
175   Y         0.101  -0.078  -0.281   0.355   0.123  -0.192   0.126  -0.121  -0.416
176   Y        -0.953  -0.907  -0.863  -0.854  -0.790  -0.715  -0.961  -0.913  -0.826
177   C         1.427   1.443   1.495   1.574   1.602   1.679   1.538   1.561   1.637
178   N        -1.266  -1.230  -1.240  -1.072  -1.026  -1.000  -1.070  -1.035  -0.991
179   G        -0.508  -0.628  -0.807  -0.292  -0.460  -0.744  -0.418  -0.566  -0.760
180   M        -0.329  -0.291  -0.345  -0.228  -0.204  -0.245  -0.526  -0.491  -0.513
181   Q        -0.523  -0.510  -0.400  -0.459  -0.444  -0.294  -0.744  -0.724  -0.578
182   L         0.101  -0.078  -0.281   0.149  -0.082  -0.362   0.126  -0.121  -0.416
183   L         0.414   0.481   0.403   0.252   0.349   0.234   0.234   0.344   0.172
184   P         1.427   1.443   1.495   1.449   1.470   1.559   1.538   1.561   1.637
185   C        -0.835  -0.872  -0.843  -0.634  -0.669  -0.628  -0.852  -0.871  -0.803
186   G         1.427   1.443   1.495   1.418   1.442   1.530   1.538   1.561   1.637
187   L        -0.195  -0.152  -0.296  -0.345  -0.272  -0.477  -0.309  -0.241  -0.438
188   S        -0.195  -0.152  -0.296  -0.211  -0.141  -0.318  -0.309  -0.241  -0.438
189   D         1.427   1.443   1.495   1.370   1.399   1.485   1.538   1.561   1.637
190   T        -0.759  -0.752  -0.833  -0.599  -0.607  -0.739  -0.744  -0.739  -0.795
191   V        -0.759  -0.654  -0.819  -0.650  -0.525  -0.756  -0.744  -0.635  -0.781
192   G         1.427   1.443   1.495   1.418   1.442   1.530   1.538   1.561   1.637
193   K        -0.759  -0.796  -0.833  -0.612  -0.669  -0.757  -0.744  -0.770  -0.790
194   H        -1.266  -1.275  -1.253  -1.172  -1.188  -1.099  -1.070  -1.067  -1.000
195   T        -0.508  -0.525  -0.773  -0.216  -0.255  -0.644  -0.418  -0.445  -0.723
196   V         1.427   1.443   1.495   1.521   1.552   1.628   1.538   1.561   1.637
197   R         0.101  -0.078  -0.281   0.379   0.145  -0.160   0.126  -0.121  -0.416
198   L         1.427   1.443   1.495   1.280   1.305   1.400   1.538   1.561   1.637
199   Y         0.235   0.216   0.298   0.109   0.058   0.176  -0.092  -0.139  -0.027
200   C         1.427   1.443   1.495   1.574   1.602   1.679   1.538   1.561   1.637
201   P         1.427   1.443   1.495   1.449   1.470   1.559   1.538   1.561   1.637
202   S        -0.329  -0.372  -0.347  -0.399  -0.439  -0.379  -0.526  -0.562  -0.514
203   C         1.427   1.443   1.495   1.574   1.602   1.679   1.538   1.561   1.637
204   Q        -0.953  -0.945  -0.883  -0.886  -0.915  -0.801  -0.961  -0.946  -0.844
205   D         1.427   1.443   1.495   1.370   1.399   1.485   1.538   1.561   1.637
206   L        -0.447  -0.435  -0.375  -0.609  -0.597  -0.488  -0.635  -0.624  -0.546
207   Y         1.427   1.443   1.495   1.489   1.516   1.597   1.538   1.561   1.637
208   L        -0.953  -0.984  -0.872  -0.999  -1.015  -0.841  -0.961  -0.979  -0.835
209   P         1.427   1.443   1.495   1.449   1.470   1.559   1.538   1.561   1.637
210   Q        -0.953  -0.926  -0.877  -0.980  -0.981  -0.927  -0.961  -0.937  -0.840
211   S         0.414   0.361   0.326   0.299   0.218   0.157   0.234   0.132   0.028
212   S         1.427   1.443   1.495   1.322   1.349   1.439   1.538   1.561   1.637
213   R         1.427   1.443   1.495   1.505   1.528   1.613   1.538   1.561   1.637
214   F        -0.447  -0.386  -0.376  -0.426  -0.342  -0.349  -0.635  -0.554  -0.548
215   L         0.101  -0.078  -0.281   0.152  -0.078  -0.356   0.126  -0.121  -0.416
216   C        -0.759  -0.714  -0.826  -0.546  -0.462  -0.670  -0.744  -0.675  -0.783
217   L        -0.523  -0.510  -0.400  -0.700  -0.663  -0.489  -0.744  -0.724  -0.578
218   E         0.235   0.323   0.346  -0.102   0.077   0.076  -0.092   0.063   0.066
219   G         1.427   1.443   1.495   1.418   1.442   1.530   1.538   1.561   1.637
220   A         0.748   0.655   0.458   0.922   0.805   0.472   0.778   0.630   0.272
221   F         0.414   0.508   0.394   0.395   0.539   0.346   0.234   0.389   0.156
222   W         0.235   0.323   0.346   0.187   0.321   0.354  -0.092   0.063   0.066
223   G         1.427   1.443   1.495   1.418   1.442   1.530   1.538   1.561   1.637
224   T         0.101  -0.078  -0.281   0.375   0.142  -0.176   0.126  -0.121  -0.416
225   S         0.178   0.211   0.300  -0.077  -0.009   0.124  -0.200  -0.149  -0.023
226   F         1.427   1.443   1.495   1.434   1.462   1.546   1.538   1.561   1.637
227   P         0.101   0.000  -0.272   0.301   0.160  -0.244   0.126  -0.015  -0.403
228   G         0.101  -0.078  -0.281   0.302   0.075  -0.211   0.126  -0.121  -0.416
229   V         0.235   0.323   0.346  -0.027   0.112   0.150  -0.092   0.063   0.066
230   F         0.414   0.481   0.403   0.328   0.439   0.273   0.234   0.344   0.172
231   L        -0.195  -0.225  -0.304  -0.280  -0.312  -0.424  -0.309  -0.333  -0.450
232   K         0.101  -0.078  -0.281   0.323   0.081  -0.267   0.126  -0.121  -0.416
233   H        -0.835  -0.918  -0.864  -0.608  -0.727  -0.672  -0.852  -0.914  -0.825
234   F         0.748   0.655   0.458   0.859   0.746   0.454   0.778   0.630   0.272
235   K         0.235   0.323   0.346   0.102   0.249   0.272  -0.092   0.063   0.066
236   E         1.427   1.443   1.495   1.236   1.274   1.358   1.538   1.561   1.637
237   L        -0.759  -0.796  -0.833  -0.759  -0.804  -0.825  -0.744  -0.770  -0.790
238   E         0.101  -0.078  -0.281   0.082  -0.143  -0.453   0.126  -0.121  -0.416
239   E        -1.696  -1.715  -1.595  -1.650  -1.674  -1.514  -1.287  -1.284  -1.134
240   Y        -1.266  -1.343  -1.270  -0.984  -1.083  -0.985  -1.070  -1.124  -1.014
241   V        -0.835  -0.918  -0.864  -0.642  -0.737  -0.667  -0.852  -0.914  -0.825
242   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
243   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
244   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
245   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
246   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
247   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
248   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
249   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
250   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
251   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
252   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
253   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
254   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
255   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
256   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
257   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
258   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
259   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
260   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
261   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
262   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
263   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
264   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
265   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
266   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
267   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
268   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
269   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
270   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
271   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
272   E        -1.578  -1.626  -1.587  -1.496  -1.583  -1.478  -1.179  -1.214  -1.128
273   R        -1.266  -1.325  -1.247  -1.088  -1.188  -1.091  -1.070  -1.104  -0.995
274   K        -1.578  -1.626  -1.587  -1.306  -1.414  -1.386  -1.179  -1.214  -1.128
275   S        -0.953  -0.976  -0.872  -0.899  -0.912  -0.785  -0.961  -0.971  -0.835
276   K        -0.447  -0.456  -0.381  -0.455  -0.496  -0.387  -0.635  -0.654  -0.554
277   E        -0.523  -0.520  -0.401  -0.728  -0.692  -0.521  -0.744  -0.737  -0.580
278   S        -0.953  -0.827  -0.849  -1.002  -0.787  -0.829  -0.961  -0.813  -0.808
279   Y         0.414   0.481   0.403   0.430   0.536   0.385   0.234   0.344   0.172
280   E        -0.447  -0.456  -0.381  -0.670  -0.665  -0.547  -0.635  -0.654  -0.554
281   L         0.414   0.320   0.327   0.232   0.069   0.078   0.234   0.057   0.029
282   K         0.414   0.397   0.338   0.452   0.423   0.299   0.234   0.196   0.051
283   V        -0.523  -0.444  -0.370  -0.700  -0.582  -0.454  -0.744  -0.645  -0.540
284   F         0.414   0.320   0.327   0.395   0.236   0.225   0.234   0.057   0.029
285   G         1.427   1.443   1.495   1.418   1.442   1.530   1.538   1.561   1.637
286   F         1.427   1.443   1.495   1.434   1.462   1.546   1.538   1.561   1.637
287   R        -0.835  -0.740  -0.826  -0.739  -0.614  -0.717  -0.852  -0.749  -0.789
288   I         0.414   0.320   0.327   0.473   0.311   0.299   0.234   0.057   0.029
289   N        -0.329  -0.291  -0.334  -0.387  -0.362  -0.385  -0.526  -0.491  -0.501
290   D        -0.195  -0.048  -0.290  -0.372  -0.138  -0.489  -0.309  -0.098  -0.429
291   E        -1.266  -1.229  -1.249  -1.294  -1.229  -1.196  -1.070  -1.023  -0.997
292   A         0.178   0.204   0.297  -0.069  -0.031   0.118  -0.200  -0.162  -0.028
293   V        -1.696  -1.715  -1.595  -1.342  -1.370  -1.213  -1.287  -1.284  -1.134
294   S        -0.195  -0.179  -0.308  -0.218  -0.211  -0.354  -0.309  -0.304  -0.461
295   G         1.427   1.443   1.495   1.418   1.442   1.530   1.538   1.561   1.637
296   P         1.427   1.443   1.495   1.449   1.470   1.559   1.538   1.561   1.637
297   R         1.427   1.443   1.495   1.505   1.528   1.613   1.538   1.561   1.637
298   M         1.427   1.443   1.495   1.590   1.613   1.694   1.538   1.561   1.637
299   K         0.235   0.218   0.297   0.172   0.139   0.256  -0.092  -0.136  -0.028
300   W         1.427   1.443   1.495   1.670   1.697   1.769   1.538   1.561   1.637
301   L         1.427   1.443   1.495   1.280   1.305   1.400   1.538   1.561   1.637
302   R         1.427   1.443   1.495   1.505   1.528   1.613   1.538   1.561   1.637
303   Q        -0.759  -0.798  -0.841  -0.563  -0.642  -0.744  -0.744  -0.792  -0.803
304   Y        -0.195  -0.224  -0.293  -0.042  -0.069  -0.181  -0.309  -0.332  -0.433
305   P         0.748   0.655   0.458   0.843   0.713   0.392   0.778   0.630   0.272
306   S        -1.696  -1.603  -1.563  -1.638  -1.539  -1.450  -1.287  -1.207  -1.113
307   T         0.235   0.210   0.297   0.094   0.021   0.143  -0.092  -0.150  -0.028
308   E        -1.266  -1.292  -1.237  -1.454  -1.505  -1.410  -1.070  -1.086  -0.988
309   E        -0.874  -0.836  -0.871  -1.094  -1.051  -1.043  -0.875  -0.841  -0.832
310   D        -0.517  -0.482  -0.388  -0.830  -0.746  -0.609  -0.733  -0.690  -0.564
311   W        -0.517  -0.505  -0.397  -0.531  -0.565  -0.421  -0.733  -0.718  -0.575
312   E        -0.295  -0.323  -0.359  -0.530  -0.597  -0.590  -0.449  -0.509  -0.528
313   E         1.427   1.443   1.495   1.220   1.253   1.342   1.538   1.561   1.637
314   F        -0.652  -0.773  -0.840  -0.508  -0.699  -0.840  -0.591  -0.738  -0.797
315   A        -1.366  -1.330  -1.252  -1.213  -1.175  -1.047  -1.159  -1.119  -1.000
316   K        -0.652  -0.702  -0.833  -0.423  -0.503  -0.732  -0.591  -0.658  -0.790
317   C        -0.008  -0.184  -0.325   0.254  -0.006  -0.297  -0.023  -0.271  -0.477
318   E        -0.008  -0.184  -0.325  -0.062  -0.298  -0.500  -0.023  -0.271  -0.477
319   F        -0.812  -0.883  -0.881  -0.805  -0.973  -1.000  -0.780  -0.867  -0.841
320   E        -0.812  -0.883  -0.881  -0.931  -1.018  -0.999  -0.780  -0.867  -0.841
321   T        -1.385  -1.319  -1.281  -1.083  -1.009  -0.951  -1.166  -1.104  -1.023
322   P         0.349   0.257   0.308   0.284   0.095   0.163   0.119  -0.062  -0.007
323   -        -0.285  -0.218  -0.309  -0.381  -0.290  -0.416  -0.409  -0.319  -0.455
324   -        -0.474  -0.399  -0.376  -0.849  -0.717  -0.702  -0.687  -0.595  -0.549
325   -        -1.473  -1.421  -1.287  -1.595  -1.545  -1.330  -1.244  -1.189  -1.028
326   -        -0.474  -0.388  -0.375  -0.860  -0.731  -0.699  -0.687  -0.584  -0.548
327   -        -0.474  -0.469  -0.367  -0.849  -0.838  -0.681  -0.687  -0.676  -0.538
328   -        -0.285  -0.200  -0.309  -0.520  -0.382  -0.590  -0.409  -0.296  -0.455
329   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
330   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
331   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
332   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
333   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
334   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
335   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
336   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
337   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
339   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
340   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
341   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
342   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
343   -        -0.474  -0.447  -0.379  -0.638  -0.573  -0.472  -0.687  -0.646  -0.552
344   -         0.525   0.617   0.431   0.510   0.650   0.319   0.425   0.570   0.224
345   -        -0.974  -0.871  -0.870  -0.998  -0.835  -0.878  -0.966  -0.847  -0.829
346   -        -1.473  -1.419  -1.287  -1.611  -1.513  -1.345  -1.244  -1.186  -1.028
347   -        -0.974  -0.849  -0.860  -0.971  -0.756  -0.842  -0.966  -0.821  -0.819
348   -        -0.974  -0.960  -0.873  -1.220  -1.197  -1.069  -0.966  -0.950  -0.832
349   -        -0.974  -0.995  -0.895  -1.034  -1.067  -0.914  -0.966  -0.985  -0.855
350   -         0.525   0.438   0.394   0.484   0.364   0.283   0.425   0.269   0.156
351   -         0.525   0.438   0.394   0.456   0.319   0.233   0.425   0.269   0.156
352   -        -1.473  -1.419  -1.287  -1.445  -1.386  -1.187  -1.244  -1.186  -1.028
353   -        -0.974  -0.995  -0.895  -0.920  -0.958  -0.832  -0.966  -0.985  -0.855
354   -         0.525   0.555   0.416   0.687   0.730   0.468   0.425   0.469   0.196
355   -        -0.285  -0.275  -0.326  -0.197  -0.191  -0.309  -0.409  -0.398  -0.478
356   -        -0.285  -0.335  -0.349  -0.344  -0.430  -0.440  -0.409  -0.484  -0.510
357   -        -0.285  -0.275  -0.326  -0.497  -0.482  -0.575  -0.409  -0.398  -0.478
358   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
359   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
360   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
361   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
362   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
363   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
364   A        -2.080  -2.012  -1.868  -1.870  -1.836  -1.590  -1.442  -1.383  -1.218
365   V        -1.723  -1.662  -1.577  -1.564  -1.500  -1.402  -1.300  -1.244  -1.121
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P43639
Output conservation file - output/P43639
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
