1     M         0.955   0.962   0.992   1.183   1.194   1.224   1.002   1.011   1.050
2     -        -0.304  -0.246  -0.288  -0.587  -0.488  -0.571  -0.539  -0.442  -0.522
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     P        -1.101  -1.115  -1.065  -1.085  -1.134  -1.093  -1.164  -1.181  -1.092
7     V        -0.924  -0.850  -1.021  -1.003  -0.886  -1.154  -0.939  -0.841  -1.039
8     Y        -0.924  -1.011  -1.043  -0.678  -0.827  -0.918  -0.939  -1.047  -1.065
9     E        -0.376  -0.391  -0.316  -0.644  -0.677  -0.532  -0.662  -0.687  -0.569
10    H        -0.376  -0.331  -0.301  -0.294  -0.215  -0.189  -0.662  -0.585  -0.545
11    L        -0.034  -0.134  -0.245  -0.116  -0.258  -0.428  -0.107  -0.261  -0.450
12    L         0.955   0.962   0.992   0.821   0.836   0.888   1.002   1.011   1.050
13    P         0.955   0.962   0.992   1.176   1.186   1.218   1.002   1.011   1.050
14    V        -0.924  -0.885  -1.025  -0.964  -0.905  -1.130  -0.939  -0.885  -1.043
15    N        -1.101  -1.113  -1.066  -1.098  -1.118  -1.077  -1.164  -1.176  -1.093
16    G         0.955   0.962   0.992   0.840   0.848   0.906   1.002   1.011   1.050
17    A        -2.228  -2.208  -2.051  -2.186  -2.163  -1.909  -1.771  -1.746  -1.548
18    W         0.955   0.962   0.992   1.228   1.236   1.266   1.002   1.011   1.050
19    R        -0.034   0.001  -0.233   0.012   0.066  -0.267  -0.107  -0.053  -0.430
20    Q        -0.924  -1.011  -1.043  -0.734  -0.885  -0.985  -0.939  -1.047  -1.065
21    D        -1.680  -1.666  -1.612  -1.610  -1.564  -1.515  -1.493  -1.476  -1.370
22    V        -0.376  -0.366  -0.310  -0.562  -0.545  -0.463  -0.662  -0.644  -0.560
23    T         0.955   0.962   0.992   0.984   0.993   1.039   1.002   1.011   1.050
24    N        -1.680  -1.713  -1.619  -1.528  -1.599  -1.432  -1.493  -1.521  -1.377
25    W        -0.376  -0.331  -0.301  -0.216  -0.138  -0.115  -0.662  -0.585  -0.545
26    L        -0.034  -0.044  -0.236  -0.068  -0.076  -0.325  -0.107  -0.121  -0.435
27    S        -1.680  -1.666  -1.612  -1.700  -1.699  -1.568  -1.493  -1.476  -1.370
28    E         0.955   0.962   0.992   0.969   0.980   1.026   1.002   1.011   1.050
29    D         0.955   0.962   0.992   1.009   1.021   1.063   1.002   1.011   1.050
30    V        -0.034  -0.134  -0.245  -0.046  -0.198  -0.373  -0.107  -0.261  -0.450
31    P         0.955   0.962   0.992   1.176   1.186   1.218   1.002   1.011   1.050
32    S         0.955   0.962   0.992   0.851   0.868   0.916   1.002   1.011   1.050
33    F         0.955   0.962   0.992   1.120   1.132   1.166   1.002   1.011   1.050
34    D         0.955   0.962   0.992   1.009   1.021   1.063   1.002   1.011   1.050
35    F        -0.376  -0.398  -0.316  -0.457  -0.519  -0.389  -0.662  -0.700  -0.570
36    G         0.955   0.962   0.992   0.814   0.818   0.881   1.002   1.011   1.050
37    G        -0.034   0.030  -0.232  -0.160  -0.073  -0.480  -0.107  -0.010  -0.427
38    Y        -0.376  -0.366  -0.310  -0.306  -0.286  -0.210  -0.662  -0.644  -0.560
39    V         0.955   0.962   0.992   0.896   0.903   0.957   1.002   1.011   1.050
40    V         0.955   0.962   0.992   0.896   0.903   0.957   1.002   1.011   1.050
41    G         0.955   0.962   0.992   0.814   0.818   0.881   1.002   1.011   1.050
42    S        -1.131  -1.100  -1.068  -1.141  -1.091  -1.056  -1.216  -1.175  -1.096
43    D        -1.680  -1.666  -1.612  -1.665  -1.657  -1.577  -1.493  -1.476  -1.370
44    L        -1.680  -1.636  -1.603  -1.443  -1.369  -1.357  -1.493  -1.442  -1.362
45    K        -1.680  -1.713  -1.619  -1.506  -1.544  -1.393  -1.493  -1.521  -1.377
46    E        -0.924  -0.908  -1.032  -0.788  -0.764  -0.941  -0.939  -0.915  -1.052
47    A        -0.034   0.027  -0.229  -0.129  -0.047  -0.458  -0.107  -0.014  -0.423
48    N        -1.131  -1.100  -1.068  -1.249  -1.188  -1.103  -1.216  -1.175  -1.096
49    L         0.955   0.962   0.992   0.821   0.836   0.888   1.002   1.011   1.050
50    Y        -0.034  -0.134  -0.245   0.281   0.147  -0.036  -0.107  -0.261  -0.450
51    C        -1.131  -1.171  -1.070  -0.968  -1.046  -0.912  -1.216  -1.250  -1.099
52    K         0.955   0.962   0.992   0.918   0.936   0.978   1.002   1.011   1.050
53    Q        -0.376  -0.398  -0.316  -0.460  -0.520  -0.399  -0.662  -0.700  -0.570
54    D        -2.228  -2.208  -2.051  -2.030  -1.968  -1.764  -1.771  -1.746  -1.548
55    G         0.955   0.962   0.992   0.814   0.818   0.881   1.002   1.011   1.050
56    M        -1.680  -1.679  -1.608  -1.654  -1.652  -1.526  -1.493  -1.488  -1.367
57    L        -1.131  -1.126  -1.066  -1.336  -1.333  -1.222  -1.216  -1.202  -1.094
58    C        -1.131  -1.087  -1.066  -1.179  -1.135  -1.086  -1.216  -1.162  -1.094
59    G         0.955   0.962   0.992   0.814   0.818   0.881   1.002   1.011   1.050
60    V        -0.034   0.027  -0.229  -0.043   0.041  -0.339  -0.107  -0.014  -0.423
61    P         0.955   0.962   0.992   1.176   1.186   1.218   1.002   1.011   1.050
62    F         0.955   0.962   0.992   1.120   1.132   1.166   1.002   1.011   1.050
63    A        -1.680  -1.666  -1.612  -1.691  -1.664  -1.559  -1.493  -1.476  -1.370
64    Q        -1.131  -1.093  -1.063  -1.046  -0.984  -0.959  -1.216  -1.171  -1.091
65    E         0.955   0.962   0.992   0.969   0.980   1.026   1.002   1.011   1.050
66    V         0.955   0.962   0.992   0.896   0.903   0.957   1.002   1.011   1.050
67    F         0.955   0.962   0.992   1.120   1.132   1.166   1.002   1.011   1.050
68    N        -1.680  -1.638  -1.604  -1.519  -1.460  -1.378  -1.493  -1.444  -1.363
69    Q        -0.034  -0.044  -0.236   0.232   0.221  -0.086  -0.107  -0.121  -0.435
70    C        -0.034  -0.044  -0.236   0.281   0.270  -0.050  -0.107  -0.121  -0.435
71    E        -1.680  -1.701  -1.612  -1.569  -1.623  -1.457  -1.493  -1.510  -1.371
72    L        -0.034  -0.134  -0.245  -0.064  -0.192  -0.329  -0.107  -0.261  -0.450
73    Q        -1.680  -1.700  -1.612  -1.506  -1.546  -1.438  -1.493  -1.509  -1.370
74    V        -0.034   0.027  -0.229   0.003   0.080  -0.257  -0.107  -0.014  -0.423
75    E        -0.376  -0.358  -0.309  -0.575  -0.538  -0.469  -0.662  -0.630  -0.559
76    W         0.955   0.962   0.992   1.228   1.236   1.266   1.002   1.011   1.050
77    L        -1.680  -1.701  -1.612  -1.707  -1.717  -1.567  -1.493  -1.510  -1.371
78    F        -1.680  -1.700  -1.612  -1.502  -1.570  -1.425  -1.493  -1.509  -1.370
79    K        -1.680  -1.701  -1.612  -1.654  -1.677  -1.538  -1.493  -1.510  -1.371
80    E         0.955   0.962   0.992   0.969   0.980   1.026   1.002   1.011   1.050
81    G         0.955   0.962   0.992   0.814   0.818   0.881   1.002   1.011   1.050
82    S        -2.228  -2.208  -2.051  -1.963  -1.910  -1.701  -1.771  -1.746  -1.548
83    F        -0.924  -1.011  -1.043  -0.603  -0.726  -0.773  -0.939  -1.047  -1.065
84    L        -0.924  -0.848  -1.022  -0.975  -0.858  -1.140  -0.939  -0.838  -1.040
85    E        -1.680  -1.621  -1.605  -1.662  -1.561  -1.551  -1.493  -1.427  -1.364
86    P        -1.101  -1.044  -1.065  -0.965  -0.866  -0.947  -1.164  -1.087  -1.092
87    S        -1.101  -1.068  -1.061  -1.278  -1.219  -1.215  -1.164  -1.118  -1.087
88    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
89    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
90    K        -1.218  -1.204  -1.085  -1.342  -1.327  -1.124  -1.309  -1.287  -1.115
91    N        -1.787  -1.763  -1.629  -1.832  -1.775  -1.579  -1.597  -1.568  -1.386
92    D        -1.787  -1.763  -1.629  -1.641  -1.588  -1.401  -1.597  -1.568  -1.386
93    S        -0.924  -0.848  -1.022  -1.071  -0.954  -1.229  -0.939  -0.838  -1.040
94    G         0.955   0.962   0.992   0.814   0.818   0.881   1.002   1.011   1.050
95    K         0.955   0.962   0.992   0.918   0.936   0.978   1.002   1.011   1.050
96    I        -0.924  -1.011  -1.043  -0.813  -0.944  -1.004  -0.939  -1.047  -1.065
97    V        -0.376  -0.398  -0.316  -0.675  -0.734  -0.578  -0.662  -0.700  -0.570
98    V        -0.034  -0.134  -0.245  -0.087  -0.247  -0.451  -0.107  -0.261  -0.450
99    A        -0.034   0.027  -0.229  -0.031   0.043  -0.279  -0.107  -0.014  -0.423
100   K        -1.131  -1.093  -1.063  -1.278  -1.217  -1.157  -1.216  -1.171  -1.091
101   I        -0.034   0.001  -0.233  -0.043   0.005  -0.346  -0.107  -0.053  -0.430
102   T        -1.131  -1.126  -1.066  -1.293  -1.273  -1.182  -1.216  -1.202  -1.094
103   G         0.955   0.962   0.992   0.814   0.818   0.881   1.002   1.011   1.050
104   P        -0.034   0.027  -0.229   0.198   0.290  -0.166  -0.107  -0.014  -0.423
105   A        -0.034  -0.044  -0.236  -0.109  -0.131  -0.433  -0.107  -0.121  -0.435
106   K        -1.680  -1.595  -1.607  -1.518  -1.372  -1.436  -1.493  -1.400  -1.366
107   N        -1.680  -1.700  -1.612  -1.534  -1.581  -1.457  -1.493  -1.509  -1.370
108   I        -0.924  -1.011  -1.043  -0.909  -1.063  -1.150  -0.939  -1.047  -1.065
109   L         0.955   0.962   0.992   0.821   0.836   0.888   1.002   1.011   1.050
110   L        -0.034  -0.134  -0.245  -0.124  -0.268  -0.443  -0.107  -0.261  -0.450
111   A        -0.034  -0.134  -0.245  -0.129  -0.298  -0.490  -0.107  -0.261  -0.450
112   E         0.955   0.962   0.992   0.969   0.980   1.026   1.002   1.011   1.050
113   R         0.955   0.962   0.992   1.127   1.132   1.172   1.002   1.011   1.050
114   T        -0.034  -0.134  -0.245   0.019  -0.139  -0.342  -0.107  -0.261  -0.450
115   A         0.955   0.962   0.992   0.855   0.858   0.919   1.002   1.011   1.050
116   L         0.955   0.962   0.992   0.821   0.836   0.888   1.002   1.011   1.050
117   N         0.955   0.962   0.992   1.106   1.121   1.152   1.002   1.011   1.050
118   I        -0.376  -0.391  -0.316  -0.656  -0.675  -0.537  -0.662  -0.687  -0.569
119   L         0.955   0.962   0.992   0.821   0.836   0.888   1.002   1.011   1.050
120   S        -0.376  -0.342  -0.306  -0.713  -0.653  -0.590  -0.662  -0.603  -0.552
121   R         0.955   0.962   0.992   1.127   1.132   1.172   1.002   1.011   1.050
122   S        -1.131  -1.172  -1.066  -1.305  -1.338  -1.142  -1.216  -1.252  -1.094
123   S         0.955   0.962   0.992   0.851   0.868   0.916   1.002   1.011   1.050
124   G         0.955   0.962   0.992   0.814   0.818   0.881   1.002   1.011   1.050
125   I        -0.376  -0.341  -0.305  -0.592  -0.534  -0.468  -0.662  -0.601  -0.552
126   A         0.955   0.962   0.992   0.855   0.858   0.919   1.002   1.011   1.050
127   T         0.955   0.962   0.992   0.984   0.993   1.039   1.002   1.011   1.050
128   A        -0.924  -0.908  -1.032  -0.752  -0.723  -0.990  -0.939  -0.915  -1.052
129   S         0.955   0.962   0.992   0.851   0.868   0.916   1.002   1.011   1.050
130   H        -0.924  -0.850  -1.021  -0.597  -0.498  -0.737  -0.939  -0.841  -1.039
131   K        -1.131  -1.087  -1.066  -1.164  -1.072  -1.069  -1.216  -1.162  -1.094
132   I        -1.131  -1.171  -1.070  -1.246  -1.312  -1.156  -1.216  -1.250  -1.099
133   I        -1.680  -1.713  -1.619  -1.760  -1.825  -1.670  -1.493  -1.521  -1.377
134   S        -2.228  -2.208  -2.051  -2.186  -2.159  -1.909  -1.771  -1.746  -1.548
135   L        -0.034  -0.134  -0.245  -0.089  -0.222  -0.376  -0.107  -0.261  -0.450
136   A        -0.034  -0.134  -0.245  -0.128  -0.292  -0.486  -0.107  -0.261  -0.450
137   R        -1.131  -1.126  -1.066  -1.104  -1.087  -1.003  -1.216  -1.202  -1.094
138   S        -1.131  -1.126  -1.066  -1.328  -1.317  -1.209  -1.216  -1.202  -1.094
139   T        -1.131  -1.100  -1.068  -1.388  -1.341  -1.248  -1.216  -1.175  -1.096
140   G         0.955   0.962   0.992   0.814   0.818   0.881   1.002   1.011   1.050
141   Y         0.955   0.962   0.992   1.169   1.184   1.211   1.002   1.011   1.050
142   K        -0.376  -0.391  -0.316  -0.562  -0.594  -0.472  -0.662  -0.687  -0.569
143   G         0.955   0.962   0.992   0.814   0.818   0.881   1.002   1.011   1.050
144   T        -0.924  -0.848  -1.022  -0.881  -0.756  -1.067  -0.939  -0.838  -1.040
145   I        -0.034  -0.134  -0.245   0.033  -0.121  -0.329  -0.107  -0.261  -0.450
146   A         0.955   0.962   0.992   0.855   0.858   0.919   1.002   1.011   1.050
147   G         0.955   0.962   0.992   0.814   0.818   0.881   1.002   1.011   1.050
148   T         0.955   0.962   0.992   0.984   0.993   1.039   1.002   1.011   1.050
149   R         0.955   0.962   0.992   1.127   1.132   1.172   1.002   1.011   1.050
150   K         0.955   0.962   0.992   0.918   0.936   0.978   1.002   1.011   1.050
151   T         0.955   0.962   0.992   0.984   0.993   1.039   1.002   1.011   1.050
152   T         0.955   0.962   0.992   0.984   0.993   1.039   1.002   1.011   1.050
153   P         0.955   0.962   0.992   1.176   1.186   1.218   1.002   1.011   1.050
154   G         0.955   0.962   0.992   0.814   0.818   0.881   1.002   1.011   1.050
155   L        -0.034  -0.134  -0.245  -0.085  -0.218  -0.369  -0.107  -0.261  -0.450
156   R         0.955   0.962   0.992   1.127   1.132   1.172   1.002   1.011   1.050
157   R        -1.131  -1.171  -1.070  -1.043  -1.118  -0.977  -1.216  -1.250  -1.099
158   L        -0.034  -0.134  -0.245  -0.142  -0.292  -0.479  -0.107  -0.261  -0.450
159   E         0.955   0.962   0.992   0.969   0.980   1.026   1.002   1.011   1.050
160   K         0.955   0.962   0.992   0.918   0.936   0.978   1.002   1.011   1.050
161   Y         0.955   0.962   0.992   1.169   1.184   1.211   1.002   1.011   1.050
162   S        -1.131  -1.172  -1.066  -1.452  -1.523  -1.330  -1.216  -1.252  -1.094
163   M         0.955   0.962   0.992   1.183   1.194   1.224   1.002   1.011   1.050
164   L        -0.034  -0.044  -0.236  -0.116  -0.125  -0.413  -0.107  -0.121  -0.435
165   V        -0.376  -0.331  -0.301  -0.592  -0.517  -0.461  -0.662  -0.585  -0.545
166   G         0.955   0.962   0.992   0.814   0.818   0.881   1.002   1.011   1.050
167   G         0.955   0.962   0.992   0.814   0.818   0.881   1.002   1.011   1.050
168   C        -1.131  -1.100  -1.068  -1.274  -1.241  -1.114  -1.216  -1.175  -1.096
169   D         0.955   0.962   0.992   1.009   1.021   1.063   1.002   1.011   1.050
170   T        -0.034  -0.044  -0.236   0.088   0.075  -0.195  -0.107  -0.121  -0.435
171   H         0.955   0.962   0.992   1.176   1.182   1.218   1.002   1.011   1.050
172   R         0.955   0.962   0.992   1.127   1.132   1.172   1.002   1.011   1.050
173   Y        -0.034  -0.134  -0.245   0.270   0.134  -0.057  -0.107  -0.261  -0.450
174   D         0.955   0.962   0.992   1.009   1.021   1.063   1.002   1.011   1.050
175   L         0.955   0.962   0.992   0.821   0.836   0.888   1.002   1.011   1.050
176   S         0.955   0.962   0.992   0.851   0.868   0.916   1.002   1.011   1.050
177   S        -0.034  -0.134  -0.245  -0.090  -0.233  -0.411  -0.107  -0.261  -0.450
178   M         0.955   0.962   0.992   1.183   1.194   1.224   1.002   1.011   1.050
179   V        -0.034  -0.134  -0.245  -0.046  -0.198  -0.373  -0.107  -0.261  -0.450
180   M         0.955   0.962   0.992   1.183   1.194   1.224   1.002   1.011   1.050
181   L         0.955   0.962   0.992   0.821   0.836   0.888   1.002   1.011   1.050
182   K         0.955   0.962   0.992   0.918   0.936   0.978   1.002   1.011   1.050
183   D         0.955   0.962   0.992   1.009   1.021   1.063   1.002   1.011   1.050
184   N         0.955   0.962   0.992   1.106   1.121   1.152   1.002   1.011   1.050
185   H         0.955   0.962   0.992   1.176   1.182   1.218   1.002   1.011   1.050
186   I        -0.376  -0.398  -0.316  -0.562  -0.617  -0.477  -0.662  -0.700  -0.570
187   W        -0.376  -0.331  -0.301  -0.317  -0.229  -0.218  -0.662  -0.585  -0.545
188   A        -0.376  -0.366  -0.310  -0.714  -0.697  -0.599  -0.662  -0.644  -0.560
189   T        -0.034  -0.134  -0.245   0.076  -0.067  -0.233  -0.107  -0.261  -0.450
190   G         0.955   0.962   0.992   0.814   0.818   0.881   1.002   1.011   1.050
191   S         0.955   0.962   0.992   0.851   0.868   0.916   1.002   1.011   1.050
192   I         0.955   0.962   0.992   0.998   1.010   1.053   1.002   1.011   1.050
193   T         0.955   0.962   0.992   0.984   0.993   1.039   1.002   1.011   1.050
194   N        -1.680  -1.713  -1.619  -1.604  -1.651  -1.488  -1.493  -1.521  -1.377
195   A        -0.034  -0.044  -0.236  -0.120  -0.141  -0.454  -0.107  -0.121  -0.435
196   V         0.955   0.962   0.992   0.896   0.903   0.957   1.002   1.011   1.050
197   K         0.955   0.962   0.992   0.918   0.936   0.978   1.002   1.011   1.050
198   N        -1.680  -1.679  -1.608  -1.717  -1.722  -1.603  -1.493  -1.488  -1.367
199   A         0.955   0.962   0.992   0.855   0.858   0.919   1.002   1.011   1.050
200   R        -0.376  -0.386  -0.315  -0.439  -0.467  -0.368  -0.662  -0.678  -0.568
201   A        -0.376  -0.391  -0.316  -0.714  -0.748  -0.610  -0.662  -0.687  -0.569
202   V        -0.034  -0.134  -0.245  -0.078  -0.241  -0.435  -0.107  -0.261  -0.450
203   C        -0.034  -0.134  -0.245   0.213   0.049  -0.197  -0.107  -0.261  -0.450
204   G         0.955   0.962   0.992   0.814   0.818   0.881   1.002   1.011   1.050
205   F         0.955   0.962   0.992   1.120   1.132   1.166   1.002   1.011   1.050
206   A        -0.034  -0.134  -0.245  -0.120  -0.282  -0.472  -0.107  -0.261  -0.450
207   V        -0.924  -1.011  -1.043  -0.914  -1.060  -1.085  -0.939  -1.047  -1.065
208   K         0.955   0.962   0.992   0.918   0.936   0.978   1.002   1.011   1.050
209   I        -0.376  -0.331  -0.301  -0.562  -0.475  -0.443  -0.662  -0.585  -0.545
210   E         0.955   0.962   0.992   0.969   0.980   1.026   1.002   1.011   1.050
211   V         0.955   0.962   0.992   0.896   0.903   0.957   1.002   1.011   1.050
212   E         0.955   0.962   0.992   0.969   0.980   1.026   1.002   1.011   1.050
213   C        -0.376  -0.366  -0.310  -0.473  -0.461  -0.349  -0.662  -0.644  -0.560
214   L        -1.131  -1.100  -1.068  -1.233  -1.151  -1.129  -1.216  -1.175  -1.096
215   S        -0.924  -0.826  -1.029  -0.930  -0.783  -1.059  -0.939  -0.810  -1.048
216   E         0.955   0.962   0.992   0.969   0.980   1.026   1.002   1.011   1.050
217   D        -0.924  -0.850  -1.021  -0.871  -0.754  -1.034  -0.939  -0.841  -1.039
218   E        -0.376  -0.331  -0.301  -0.523  -0.443  -0.399  -0.662  -0.585  -0.545
219   A         0.955   0.962   0.992   0.855   0.858   0.919   1.002   1.011   1.050
220   T        -2.228  -2.208  -2.051  -1.956  -1.929  -1.694  -1.771  -1.746  -1.548
221   E         0.955   0.962   0.992   0.969   0.980   1.026   1.002   1.011   1.050
222   A         0.955   0.962   0.992   0.855   0.858   0.919   1.002   1.011   1.050
223   I         0.955   0.962   0.992   0.998   1.010   1.053   1.002   1.011   1.050
224   E        -1.131  -1.087  -1.066  -1.292  -1.242  -1.160  -1.216  -1.162  -1.094
225   A         0.955   0.962   0.992   0.855   0.858   0.919   1.002   1.011   1.050
226   G         0.955   0.962   0.992   0.814   0.818   0.881   1.002   1.011   1.050
227   A         0.955   0.962   0.992   0.855   0.858   0.919   1.002   1.011   1.050
228   D         0.955   0.962   0.992   1.009   1.021   1.063   1.002   1.011   1.050
229   V        -0.376  -0.398  -0.316  -0.592  -0.633  -0.484  -0.662  -0.700  -0.570
230   I         0.955   0.962   0.992   0.998   1.010   1.053   1.002   1.011   1.050
231   M         0.955   0.962   0.992   1.183   1.194   1.224   1.002   1.011   1.050
232   L         0.955   0.962   0.992   0.821   0.836   0.888   1.002   1.011   1.050
233   D         0.955   0.962   0.992   1.009   1.021   1.063   1.002   1.011   1.050
234   N         0.955   0.962   0.992   1.106   1.121   1.152   1.002   1.011   1.050
235   F         0.955   0.962   0.992   1.120   1.132   1.166   1.002   1.011   1.050
236   K        -1.680  -1.700  -1.612  -1.656  -1.682  -1.539  -1.493  -1.509  -1.370
237   G         0.955   0.962   0.992   0.814   0.818   0.881   1.002   1.011   1.050
238   D        -1.680  -1.636  -1.603  -1.554  -1.493  -1.428  -1.493  -1.442  -1.362
239   G        -0.376  -0.331  -0.301  -0.679  -0.609  -0.542  -0.662  -0.585  -0.545
240   L        -0.034  -0.134  -0.245  -0.142  -0.292  -0.479  -0.107  -0.261  -0.450
241   K        -1.131  -1.108  -1.062  -1.011  -0.976  -0.917  -1.216  -1.186  -1.090
242   M        -1.680  -1.595  -1.607  -1.554  -1.438  -1.414  -1.493  -1.400  -1.366
243   C        -0.924  -0.850  -1.021  -0.923  -0.823  -1.042  -0.939  -0.841  -1.039
244   A         0.955   0.962   0.992   0.855   0.858   0.919   1.002   1.011   1.050
245   Q        -0.034  -0.134  -0.245   0.232   0.090  -0.102  -0.107  -0.261  -0.450
246   S         0.955   0.962   0.992   0.851   0.868   0.916   1.002   1.011   1.050
247   L        -0.034  -0.044  -0.236  -0.116  -0.125  -0.413  -0.107  -0.121  -0.435
248   K         0.955   0.962   0.992   0.918   0.936   0.978   1.002   1.011   1.050
249   N        -1.680  -1.713  -1.619  -1.604  -1.651  -1.488  -1.493  -1.521  -1.377
250   K        -0.924  -0.956  -1.033  -0.817  -0.859  -0.944  -0.939  -0.980  -1.053
251   W        -0.924  -0.826  -1.029  -0.522  -0.382  -0.701  -0.939  -0.810  -1.048
252   N        -1.131  -1.093  -1.063  -1.207  -1.162  -1.091  -1.216  -1.171  -1.091
253   G         0.955   0.962   0.992   0.814   0.818   0.881   1.002   1.011   1.050
254   K        -0.376  -0.358  -0.309  -0.581  -0.545  -0.467  -0.662  -0.630  -0.559
255   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
256   K         0.955   0.962   0.992   0.918   0.936   0.978   1.002   1.011   1.050
257   H        -1.131  -1.171  -1.070  -1.098  -1.129  -0.967  -1.216  -1.250  -1.099
258   F         0.955   0.962   0.992   1.120   1.132   1.166   1.002   1.011   1.050
259   L        -0.034  -0.044  -0.236  -0.068  -0.076  -0.325  -0.107  -0.121  -0.435
260   L         0.955   0.962   0.992   0.821   0.836   0.888   1.002   1.011   1.050
261   E         0.955   0.962   0.992   0.969   0.980   1.026   1.002   1.011   1.050
262   C        -0.034  -0.134  -0.245   0.232   0.074  -0.160  -0.107  -0.261  -0.450
263   S         0.955   0.962   0.992   0.851   0.868   0.916   1.002   1.011   1.050
264   G         0.955   0.962   0.992   0.814   0.818   0.881   1.002   1.011   1.050
265   G         0.955   0.962   0.992   0.814   0.818   0.881   1.002   1.011   1.050
266   L         0.955   0.962   0.992   0.821   0.836   0.888   1.002   1.011   1.050
267   N        -0.034   0.001  -0.233   0.070   0.119  -0.223  -0.107  -0.053  -0.430
268   L        -0.924  -1.011  -1.043  -1.046  -1.191  -1.231  -0.939  -1.047  -1.065
269   D        -1.680  -1.621  -1.605  -1.578  -1.482  -1.468  -1.493  -1.427  -1.364
270   N         0.955   0.962   0.992   1.106   1.121   1.152   1.002   1.011   1.050
271   L        -0.924  -1.011  -1.043  -1.036  -1.179  -1.217  -0.939  -1.047  -1.065
272   E        -1.131  -1.126  -1.066  -1.366  -1.346  -1.250  -1.216  -1.202  -1.094
273   E        -0.034   0.001  -0.233  -0.094  -0.038  -0.397  -0.107  -0.053  -0.430
274   Y         0.955   0.962   0.992   1.169   1.184   1.211   1.002   1.011   1.050
275   L        -0.034  -0.134  -0.245  -0.116  -0.258  -0.428  -0.107  -0.261  -0.450
276   C        -0.924  -0.887  -1.023  -0.681  -0.618  -0.902  -0.939  -0.889  -1.041
277   D        -0.924  -0.978  -1.039  -0.664  -0.737  -0.847  -0.939  -1.006  -1.060
278   D        -0.034  -0.044  -0.236   0.105   0.095  -0.189  -0.107  -0.121  -0.435
279   I         0.955   0.962   0.992   0.998   1.010   1.053   1.002   1.011   1.050
280   D         0.955   0.962   0.992   1.009   1.021   1.063   1.002   1.011   1.050
281   I         0.955   0.962   0.992   0.998   1.010   1.053   1.002   1.011   1.050
282   Y        -0.034  -0.134  -0.245   0.184   0.028  -0.220  -0.107  -0.261  -0.450
283   S         0.955   0.962   0.992   0.851   0.868   0.916   1.002   1.011   1.050
284   T         0.955   0.962   0.992   0.984   0.993   1.039   1.002   1.011   1.050
285   S         0.955   0.962   0.992   0.851   0.868   0.916   1.002   1.011   1.050
286   S         0.955   0.962   0.992   0.851   0.868   0.916   1.002   1.011   1.050
287   I         0.955   0.962   0.992   0.998   1.010   1.053   1.002   1.011   1.050
288   H         0.955   0.962   0.992   1.176   1.182   1.218   1.002   1.011   1.050
289   Q         0.955   0.962   0.992   1.144   1.158   1.188   1.002   1.011   1.050
290   G         0.955   0.962   0.992   0.814   0.818   0.881   1.002   1.011   1.050
291   T        -1.131  -1.093  -1.063  -1.183  -1.144  -1.034  -1.216  -1.171  -1.091
292   P        -1.131  -1.093  -1.063  -1.225  -1.154  -1.116  -1.216  -1.171  -1.091
293   V        -1.680  -1.680  -1.608  -1.550  -1.539  -1.438  -1.493  -1.490  -1.367
294   I        -0.376  -0.342  -0.306  -0.592  -0.536  -0.469  -0.662  -0.603  -0.552
295   D         0.955   0.962   0.992   1.009   1.021   1.063   1.002   1.011   1.050
296   F         0.955   0.962   0.992   1.120   1.132   1.166   1.002   1.011   1.050
297   S         0.955   0.962   0.992   0.851   0.868   0.916   1.002   1.011   1.050
298   L         0.955   0.962   0.992   0.821   0.836   0.888   1.002   1.011   1.050
299   K         0.955   0.962   0.992   0.918   0.936   0.978   1.002   1.011   1.050
300   L        -0.034   0.001  -0.233   0.015   0.071  -0.339  -0.107  -0.053  -0.430
301   -        -0.416  -0.408  -0.318  -0.476  -0.459  -0.317  -0.731  -0.717  -0.573
302   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
303   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
304   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
305   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
306   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
307   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
308   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
309   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
310   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
311   A        -1.131  -1.129  -1.064  -1.315  -1.308  -1.152  -1.216  -1.206  -1.092
312   H        -2.228  -2.208  -2.051  -2.020  -1.998  -1.754  -1.771  -1.746  -1.548
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P43619
Output conservation file - output/P43619
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
