1     M         1.509   1.509   1.509   1.865   1.865   1.865   1.509   1.509   1.509
2     S        -0.660  -0.660  -0.660  -1.035  -1.035  -1.035  -0.660  -0.660  -0.660
3     T        -0.660  -0.660  -0.660  -0.695  -0.695  -0.695  -0.660  -0.660  -0.660
4     P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    E        -0.660  -0.660  -0.660  -0.838  -0.838  -0.838  -0.660  -0.660  -0.660
13    N        -0.660  -0.660  -0.660  -0.726  -0.726  -0.726  -0.660  -0.660  -0.660
14    T        -0.660  -0.660  -0.660  -0.814  -0.814  -0.814  -0.660  -0.660  -0.660
15    E         1.509   1.509   1.509   1.193   1.193   1.193   1.509   1.509   1.509
16    V        -0.660  -0.660  -0.660  -0.687  -0.687  -0.687  -0.660  -0.660  -0.660
17    S         1.509   1.509   1.509   1.356   1.356   1.356   1.509   1.509   1.509
18    E        -0.660  -0.660  -0.660  -0.806  -0.806  -0.806  -0.660  -0.660  -0.660
19    I         1.509   1.509   1.509   1.558   1.558   1.558   1.509   1.509   1.509
20    R        -0.660  -0.660  -0.660  -0.846  -0.846  -0.846  -0.660  -0.660  -0.660
21    T         1.509   1.509   1.509   1.642   1.642   1.642   1.509   1.509   1.509
22    P         1.509   1.509   1.509   1.642   1.642   1.642   1.509   1.509   1.509
23    F         1.509   1.509   1.509   1.815   1.815   1.815   1.509   1.509   1.509
24    R        -0.660  -0.660  -0.660  -0.542  -0.542  -0.542  -0.660  -0.660  -0.660
25    E        -0.660  -0.660  -0.660  -0.846  -0.846  -0.846  -0.660  -0.660  -0.660
26    R         1.509   1.509   1.509   1.600   1.600   1.600   1.509   1.509   1.509
27    A         1.509   1.509   1.509   1.754   1.754   1.754   1.509   1.509   1.509
28    L        -0.660  -0.660  -0.660  -1.085  -1.085  -1.085  -0.660  -0.660  -0.660
29    E        -0.660  -0.660  -0.660  -0.806  -0.806  -0.806  -0.660  -0.660  -0.660
30    E        -0.660  -0.660  -0.660  -1.085  -1.085  -1.085  -0.660  -0.660  -0.660
31    Q        -0.660  -0.660  -0.660  -0.565  -0.565  -0.565  -0.660  -0.660  -0.660
32    R         1.509   1.509   1.509   1.600   1.600   1.600   1.509   1.509   1.509
33    L         1.509   1.509   1.509   1.291   1.291   1.291   1.509   1.509   1.509
34    K         1.509   1.509   1.509   1.610   1.610   1.610   1.509   1.509   1.509
35    D        -0.660  -0.660  -0.660  -0.985  -0.985  -0.985  -0.660  -0.660  -0.660
36    E        -0.660  -0.660  -0.660  -0.870  -0.870  -0.870  -0.660  -0.660  -0.660
37    V        -0.660  -0.660  -0.660  -0.321  -0.321  -0.321  -0.660  -0.660  -0.660
38    L         1.509   1.509   1.509   1.291   1.291   1.291   1.509   1.509   1.509
39    I        -0.660  -0.660  -0.660  -0.806  -0.806  -0.806  -0.660  -0.660  -0.660
40    R        -0.660  -0.660  -0.660  -0.846  -0.846  -0.846  -0.660  -0.660  -0.660
41    N        -0.660  -0.660  -0.660  -0.774  -0.774  -0.774  -0.660  -0.660  -0.660
42    T         1.509   1.509   1.509   1.642   1.642   1.642   1.509   1.509   1.509
43    P         1.509   1.509   1.509   1.642   1.642   1.642   1.509   1.509   1.509
44    G         1.509   1.509   1.509   1.805   1.805   1.805   1.509   1.509   1.509
45    Y        -0.660  -0.660  -0.660  -0.580  -0.580  -0.580  -0.660  -0.660  -0.660
46    R        -0.660  -0.660  -0.660  -0.542  -0.542  -0.542  -0.660  -0.660  -0.660
47    K         1.509   1.509   1.509   1.610   1.610   1.610   1.509   1.509   1.509
48    L        -0.660  -0.660  -0.660  -0.774  -0.774  -0.774  -0.660  -0.660  -0.660
49    L        -0.660  -0.660  -0.660  -0.774  -0.774  -0.774  -0.660  -0.660  -0.660
50    S        -0.660  -0.660  -0.660  -0.687  -0.687  -0.687  -0.660  -0.660  -0.660
51    A        -0.660  -0.660  -0.660  -0.285  -0.285  -0.285  -0.660  -0.660  -0.660
52    S        -0.660  -0.660  -0.660  -0.862  -0.862  -0.862  -0.660  -0.660  -0.660
53    T        -0.660  -0.660  -0.660  -0.482  -0.482  -0.482  -0.660  -0.660  -0.660
54    K        -0.660  -0.660  -0.660  -0.394  -0.394  -0.394  -0.660  -0.660  -0.660
55    S        -0.660  -0.660  -0.660  -0.774  -0.774  -0.774  -0.660  -0.660  -0.660
56    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
57    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
58    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
59    L         1.509   1.509   1.509   1.291   1.291   1.291   1.509   1.509   1.509
60    N        -0.660  -0.660  -0.660  -0.588  -0.588  -0.588  -0.660  -0.660  -0.660
61    K        -0.660  -0.660  -0.660  -0.588  -0.588  -0.588  -0.660  -0.660  -0.660
62    D        -0.660  -0.660  -0.660  -0.862  -0.862  -0.862  -0.660  -0.660  -0.660
63    P         1.509   1.509   1.509   1.642   1.642   1.642   1.509   1.509   1.509
64    N         1.509   1.509   1.509   1.537   1.537   1.537   1.509   1.509   1.509
65    E         1.509   1.509   1.509   1.193   1.193   1.193   1.509   1.509   1.509
66    V        -0.660  -0.660  -0.660  -0.687  -0.687  -0.687  -0.660  -0.660  -0.660
67    R         1.509   1.509   1.509   1.600   1.600   1.600   1.509   1.509   1.509
68    S        -0.660  -0.660  -0.660  -0.527  -0.527  -0.527  -0.660  -0.660  -0.660
69    F         1.509   1.509   1.509   1.815   1.815   1.815   1.509   1.509   1.509
70    L         1.509   1.509   1.509   1.291   1.291   1.291   1.509   1.509   1.509
71    Q        -0.660  -0.660  -0.660  -0.565  -0.565  -0.565  -0.660  -0.660  -0.660
72    D        -0.660  -0.660  -0.660  -0.985  -0.985  -0.985  -0.660  -0.660  -0.660
73    L         1.509   1.509   1.509   1.291   1.291   1.291   1.509   1.509   1.509
74    S        -0.660  -0.660  -0.660  -0.862  -0.862  -0.862  -0.660  -0.660  -0.660
75    Q        -0.660  -0.660  -0.660  -0.750  -0.750  -0.750  -0.660  -0.660  -0.660
76    V        -0.660  -0.660  -0.660  -0.401  -0.401  -0.401  -0.660  -0.660  -0.660
77    L         1.509   1.509   1.509   1.291   1.291   1.291   1.509   1.509   1.509
78    A         1.509   1.509   1.509   1.754   1.754   1.754   1.509   1.509   1.509
79    R        -0.660  -0.660  -0.660  -0.726  -0.726  -0.726  -0.660  -0.660  -0.660
80    K        -0.660  -0.660  -0.660  -0.542  -0.542  -0.542  -0.660  -0.660  -0.660
81    S        -0.660  -0.660  -0.660  -0.572  -0.572  -0.572  -0.660  -0.660  -0.660
82    Q        -0.660  -0.660  -0.660  -0.703  -0.703  -0.703  -0.660  -0.660  -0.660
83    G         1.509   1.509   1.509   1.805   1.805   1.805   1.509   1.509   1.509
84    N        -0.660  -0.660  -0.660  -0.588  -0.588  -0.588  -0.660  -0.660  -0.660
85    D        -0.660  -0.660  -0.660  -0.703  -0.703  -0.703  -0.660  -0.660  -0.660
86    T        -0.660  -0.660  -0.660  -0.314  -0.314  -0.314  -0.660  -0.660  -0.660
87    T        -0.660  -0.660  -0.660  -0.372  -0.372  -0.372  -0.660  -0.660  -0.660
88    T        -0.660  -0.660  -0.660  -0.482  -0.482  -0.482  -0.660  -0.660  -0.660
89    N        -0.660  -0.660  -0.660  -0.774  -0.774  -0.774  -0.660  -0.660  -0.660
90    K        -0.660  -0.660  -0.660  -0.588  -0.588  -0.588  -0.660  -0.660  -0.660
91    T        -0.660  -0.660  -0.660  -0.742  -0.742  -0.742  -0.660  -0.660  -0.660
92    Q         1.509   1.509   1.509   1.569   1.569   1.569   1.509   1.509   1.509
93    A        -0.660  -0.660  -0.660  -0.565  -0.565  -0.565  -0.660  -0.660  -0.660
94    R        -0.660  -0.660  -0.660  -0.542  -0.542  -0.542  -0.660  -0.660  -0.660
95    N        -0.660  -0.660  -0.660  -0.822  -0.822  -0.822  -0.660  -0.660  -0.660
96    L         1.509   1.509   1.509   1.291   1.291   1.291   1.509   1.509   1.509
97    I        -0.660  -0.660  -0.660  -0.711  -0.711  -0.711  -0.660  -0.660  -0.660
98    D        -0.660  -0.660  -0.660  -0.565  -0.565  -0.565  -0.660  -0.660  -0.660
99    E         1.509   1.509   1.509   1.193   1.193   1.193   1.509   1.509   1.509
100   L        -0.660  -0.660  -0.660  -1.085  -1.085  -1.085  -0.660  -0.660  -0.660
101   A        -0.660  -0.660  -0.660  -0.408  -0.408  -0.408  -0.660  -0.660  -0.660
102   Y        -0.660  -0.660  -0.660  -0.165  -0.165  -0.165  -0.660  -0.660  -0.660
103   E         1.509   1.509   1.509   1.193   1.193   1.193   1.509   1.509   1.509
104   E        -0.660  -0.660  -0.660  -0.985  -0.985  -0.985  -0.660  -0.660  -0.660
105   S        -0.660  -0.660  -0.660  -0.774  -0.774  -0.774  -0.660  -0.660  -0.660
106   Q        -0.660  -0.660  -0.660  -0.870  -0.870  -0.870  -0.660  -0.660  -0.660
107   P         1.509   1.509   1.509   1.642   1.642   1.642   1.509   1.509   1.509
108   E        -0.660  -0.660  -0.660  -0.985  -0.985  -0.985  -0.660  -0.660  -0.660
109   E        -0.660  -0.660  -0.660  -0.726  -0.726  -0.726  -0.660  -0.660  -0.660
110   N        -0.660  -0.660  -0.660  -0.408  -0.408  -0.408  -0.660  -0.660  -0.660
111   E        -0.660  -0.660  -0.660  -0.846  -0.846  -0.846  -0.660  -0.660  -0.660
112   L        -0.660  -0.660  -0.660  -0.910  -0.910  -0.910  -0.660  -0.660  -0.660
113   L        -0.660  -0.660  -0.660  -0.742  -0.742  -0.742  -0.660  -0.660  -0.660
114   R        -0.660  -0.660  -0.660  -0.726  -0.726  -0.726  -0.660  -0.660  -0.660
115   S         1.509   1.509   1.509   1.356   1.356   1.356   1.509   1.509   1.509
116   R        -0.660  -0.660  -0.660  -0.580  -0.580  -0.580  -0.660  -0.660  -0.660
117   S        -0.660  -0.660  -0.660  -0.750  -0.750  -0.750  -0.660  -0.660  -0.660
118   E        -0.660  -0.660  -0.660  -0.985  -0.985  -0.985  -0.660  -0.660  -0.660
119   K        -0.660  -0.660  -0.660  -0.565  -0.565  -0.565  -0.660  -0.660  -0.660
120   L        -0.660  -0.660  -0.660  -0.798  -0.798  -0.798  -0.660  -0.660  -0.660
121   T        -0.660  -0.660  -0.660  -0.542  -0.542  -0.542  -0.660  -0.660  -0.660
122   D        -0.660  -0.660  -0.660  -0.985  -0.985  -0.985  -0.660  -0.660  -0.660
123   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
124   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
125   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
126   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
127   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
128   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
129   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
130   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
131   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
132   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
133   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
134   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
135   S         1.509   1.509   1.509   1.356   1.356   1.356   1.509   1.509   1.509
136   L         1.509   1.509   1.509   1.291   1.291   1.291   1.509   1.509   1.509
137   S         1.509   1.509   1.509   1.356   1.356   1.356   1.509   1.509   1.509
138   Q        -0.660  -0.660  -0.660  -0.535  -0.535  -0.535  -0.660  -0.660  -0.660
139   T        -0.660  -0.660  -0.660  -0.408  -0.408  -0.408  -0.660  -0.660  -0.660
140   V         1.509   1.509   1.509   1.652   1.652   1.652   1.509   1.509   1.509
141   F         1.509   1.509   1.509   1.815   1.815   1.815   1.509   1.509   1.509
142   A        -0.660  -0.660  -0.660  -0.610  -0.610  -0.610  -0.660  -0.660  -0.660
143   K        -0.660  -0.660  -0.660  -0.565  -0.565  -0.565  -0.660  -0.660  -0.660
144   L        -0.660  -0.660  -0.660  -0.806  -0.806  -0.806  -0.660  -0.660  -0.660
145   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
146   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
147   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
148   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
149   K         1.509   1.509   1.509   1.610   1.610   1.610   1.509   1.509   1.509
150   G        -0.660  -0.660  -0.660  -0.527  -0.527  -0.527  -0.660  -0.660  -0.660
151   L        -0.660  -0.660  -0.660  -0.742  -0.742  -0.742  -0.660  -0.660  -0.660
152   K         1.509   1.509   1.509   1.610   1.610   1.610   1.509   1.509   1.509
153   S        -0.660  -0.660  -0.660  -0.610  -0.610  -0.610  -0.660  -0.660  -0.660
154   R         1.509   1.509   1.509   1.600   1.600   1.600   1.509   1.509   1.509
155   K         1.509   1.509   1.509   1.610   1.610   1.610   1.509   1.509   1.509
156   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
157   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
158   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
159   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
160   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
161   I        -0.660  -0.660  -0.660  -0.711  -0.711  -0.711  -0.660  -0.660  -0.660
162   D        -0.660  -0.660  -0.660  -0.985  -0.985  -0.985  -0.660  -0.660  -0.660
163   P        -0.660  -0.660  -0.660  -0.695  -0.695  -0.695  -0.660  -0.660  -0.660
164   I        -0.660  -0.660  -0.660  -0.423  -0.423  -0.423  -0.660  -0.660  -0.660
165   I        -0.660  -0.660  -0.660  -0.542  -0.542  -0.542  -0.660  -0.660  -0.660
166   I         1.509   1.509   1.509   1.558   1.558   1.558   1.509   1.509   1.509
167   Q         1.509   1.509   1.509   1.569   1.569   1.569   1.509   1.509   1.509
168   D         1.509   1.509   1.509   1.421   1.421   1.421   1.509   1.509   1.509
169   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
170   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
171   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
172   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
173   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
174   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
175   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
176   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
177   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
178   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
179   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
180   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
181   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
182   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
183   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
184   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
185   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
186   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
187   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
188   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
189   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
190   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
191   V        -0.660  -0.660  -0.660  -0.542  -0.542  -0.542  -0.660  -0.660  -0.660
192   P         1.509   1.509   1.509   1.642   1.642   1.642   1.509   1.509   1.509
193   T        -0.660  -0.660  -0.660  -0.695  -0.695  -0.695  -0.660  -0.660  -0.660
194   T        -0.660  -0.660  -0.660  -0.695  -0.695  -0.695  -0.660  -0.660  -0.660
195   G        -0.660  -0.660  -0.660  -0.372  -0.372  -0.372  -0.660  -0.660  -0.660
196   H        -0.660  -0.660  -0.660  -0.235  -0.235  -0.235  -0.660  -0.660  -0.660
197   E        -0.660  -0.660  -0.660  -0.870  -0.870  -0.870  -0.660  -0.660  -0.660
198   D        -0.660  -0.660  -0.660  -0.711  -0.711  -0.711  -0.660  -0.660  -0.660
199   E         1.509   1.509   1.509   1.193   1.193   1.193   1.509   1.509   1.509
200   L        -0.660  -0.660  -0.660  -0.742  -0.742  -0.742  -0.660  -0.660  -0.660
201   T         1.509   1.509   1.509   1.642   1.642   1.642   1.509   1.509   1.509
202   V        -0.660  -0.660  -0.660  -0.542  -0.542  -0.542  -0.660  -0.660  -0.660
203   H        -0.660  -0.660  -0.660  -0.626  -0.626  -0.626  -0.660  -0.660  -0.660
204   S         1.509   1.509   1.509   1.356   1.356   1.356   1.509   1.509   1.509
205   P         1.509   1.509   1.509   1.642   1.642   1.642   1.509   1.509   1.509
206   D        -0.660  -0.660  -0.660  -0.985  -0.985  -0.985  -0.660  -0.660  -0.660
207   K        -0.660  -0.660  -0.660  -0.542  -0.542  -0.542  -0.660  -0.660  -0.660
208   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
209   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
210   A         1.509   1.509   1.509   1.754   1.754   1.754   1.509   1.509   1.509
211   N        -0.660  -0.660  -0.660  -0.726  -0.726  -0.726  -0.660  -0.660  -0.660
212   S         1.509   1.509   1.509   1.356   1.356   1.356   1.509   1.509   1.509
213   I        -0.660  -0.660  -0.660  -0.758  -0.758  -0.758  -0.660  -0.660  -0.660
214   S        -0.660  -0.660  -0.660  -0.960  -0.960  -0.960  -0.660  -0.660  -0.660
215   M        -0.660  -0.660  -0.660  -0.158  -0.158  -0.158  -0.660  -0.660  -0.660
216   E        -0.660  -0.660  -0.660  -0.649  -0.649  -0.649  -0.660  -0.660  -0.660
217   V        -0.660  -0.660  -0.660  -0.542  -0.542  -0.542  -0.660  -0.660  -0.660
218   L        -0.660  -0.660  -0.660  -0.742  -0.742  -0.742  -0.660  -0.660  -0.660
219   R         1.509   1.509   1.509   1.600   1.600   1.600   1.509   1.509   1.509
220   T        -0.660  -0.660  -0.660  -0.482  -0.482  -0.482  -0.660  -0.660  -0.660
221   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
222   S         1.509   1.509   1.509   1.356   1.356   1.356   1.509   1.509   1.509
223   P         1.509   1.509   1.509   1.642   1.642   1.642   1.509   1.509   1.509
224   S        -0.660  -0.660  -0.660  -0.695  -0.695  -0.695  -0.660  -0.660  -0.660
225   I        -0.660  -0.660  -0.660  -0.430  -0.430  -0.430  -0.660  -0.660  -0.660
226   G        -0.660  -0.660  -0.660  -0.394  -0.394  -0.394  -0.660  -0.660  -0.660
227   M        -0.660  -0.660  -0.660  -0.179  -0.179  -0.179  -0.660  -0.660  -0.660
228   D         1.509   1.509   1.509   1.421   1.421   1.421   1.509   1.509   1.509
229   Q        -0.660  -0.660  -0.660  -0.870  -0.870  -0.870  -0.660  -0.660  -0.660
230   V        -0.660  -0.660  -0.660  -0.512  -0.512  -0.512  -0.660  -0.660  -0.660
231   D         1.509   1.509   1.509   1.421   1.421   1.421   1.509   1.509   1.509
232   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
233   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
234   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
235   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
236   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
237   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
238   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
239   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
240   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
241   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
242   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
243   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
244   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
245   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
246   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
247   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
248   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
249   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
250   L        -0.660  -0.660  -0.660  -0.734  -0.734  -0.734  -0.660  -0.660  -0.660
251   S        -0.660  -0.660  -0.660  -0.565  -0.565  -0.565  -0.660  -0.660  -0.660
252   E        -0.660  -0.660  -0.660  -0.626  -0.626  -0.626  -0.660  -0.660  -0.660
253   D        -0.660  -0.660  -0.660  -0.726  -0.726  -0.726  -0.660  -0.660  -0.660
254   L        -0.660  -0.660  -0.660  -0.580  -0.580  -0.580  -0.660  -0.660  -0.660
255   P        -0.660  -0.660  -0.660  -0.695  -0.695  -0.695  -0.660  -0.660  -0.660
256   S        -0.660  -0.660  -0.660  -0.695  -0.695  -0.695  -0.660  -0.660  -0.660
257   D         1.509   1.509   1.509   1.421   1.421   1.421   1.509   1.509   1.509
258   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
259   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
260   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
261   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
262   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
263   E         1.509   1.509   1.509   1.193   1.193   1.193   1.509   1.509   1.509
264   E         1.509   1.509   1.509   1.193   1.193   1.193   1.509   1.509   1.509
265   A        -0.660  -0.660  -0.660  -0.610  -0.610  -0.610  -0.660  -0.660  -0.660
266   E        -0.660  -0.660  -0.660  -0.878  -0.878  -0.878  -0.660  -0.660  -0.660
267   N         1.509   1.509   1.509   1.537   1.537   1.537   1.509   1.509   1.509
268   E         1.509   1.509   1.509   1.193   1.193   1.193   1.509   1.509   1.509
269   D        -0.660  -0.660  -0.660  -0.985  -0.985  -0.985  -0.660  -0.660  -0.660
270   Y        -0.660  -0.660  -0.660  -0.386  -0.386  -0.386  -0.660  -0.660  -0.660
271   S        -0.660  -0.660  -0.660  -1.035  -1.035  -1.035  -0.660  -0.660  -0.660
272   F        -0.660  -0.660  -0.660  -0.423  -0.423  -0.423  -0.660  -0.660  -0.660
273   E         1.509   1.509   1.509   1.193   1.193   1.193   1.509   1.509   1.509
274   N        -0.660  -0.660  -0.660  -0.894  -0.894  -0.894  -0.660  -0.660  -0.660
275   T        -0.660  -0.660  -0.660  -0.695  -0.695  -0.695  -0.660  -0.660  -0.660
276   S        -0.660  -0.660  -0.660  -0.535  -0.535  -0.535  -0.660  -0.660  -0.660
277   D        -0.660  -0.660  -0.660  -0.672  -0.672  -0.672  -0.660  -0.660  -0.660
278   E         1.509   1.509   1.509   1.193   1.193   1.193   1.509   1.509   1.509
279   N        -0.660  -0.660  -0.660  -0.774  -0.774  -0.774  -0.660  -0.660  -0.660
280   L         1.509   1.509   1.509   1.291   1.291   1.291   1.509   1.509   1.509
281   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
282   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
283   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
284   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
285   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
286   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
287   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
288   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
289   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
290   L         1.509   1.509   1.509   1.291   1.291   1.291   1.509   1.509   1.509
291   N        -0.660  -0.660  -0.660  -0.618  -0.618  -0.618  -0.660  -0.660  -0.660
292   V         1.509   1.509   1.509   1.652   1.652   1.652   1.509   1.509   1.509
293   P         1.509   1.509   1.509   1.642   1.642   1.642   1.509   1.509   1.509
294   A        -0.660  -0.660  -0.660  -0.726  -0.726  -0.726  -0.660  -0.660  -0.660
295   V        -0.660  -0.660  -0.660  -0.734  -0.734  -0.734  -0.660  -0.660  -0.660
296   R         1.509   1.509   1.509   1.600   1.600   1.600   1.509   1.509   1.509
297   R        -0.660  -0.660  -0.660  -0.542  -0.542  -0.542  -0.660  -0.660  -0.660
298   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
299   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
300   S        -0.660  -0.660  -0.660  -1.035  -1.035  -1.035  -0.660  -0.660  -0.660
301   S         1.509   1.509   1.509   1.356   1.356   1.356   1.509   1.509   1.509
302   I         1.509   1.509   1.509   1.558   1.558   1.558   1.509   1.509   1.509
303   K        -0.660  -0.660  -0.660  -0.512  -0.512  -0.512  -0.660  -0.660  -0.660
304   P        -0.660  -0.660  -0.660  -0.372  -0.372  -0.372  -0.660  -0.660  -0.660
305   L         1.509   1.509   1.509   1.291   1.291   1.291   1.509   1.509   1.509
306   Q         1.509   1.509   1.509   1.569   1.569   1.569   1.509   1.509   1.509
307   I        -0.660  -0.660  -0.660  -0.626  -0.626  -0.626  -0.660  -0.660  -0.660
308   M        -0.660  -0.660  -0.660  -0.386  -0.386  -0.386  -0.660  -0.660  -0.660
309   D         1.509   1.509   1.509   1.421   1.421   1.421   1.509   1.509   1.509
310   L        -0.660  -0.660  -0.660  -0.572  -0.572  -0.572  -0.660  -0.660  -0.660
311   K        -0.660  -0.660  -0.660  -0.512  -0.512  -0.512  -0.660  -0.660  -0.660
312   H        -0.660  -0.660  -0.660  -0.343  -0.343  -0.343  -0.660  -0.660  -0.660
313   L        -0.660  -0.660  -0.660  -0.774  -0.774  -0.774  -0.660  -0.660  -0.660
314   T        -0.660  -0.660  -0.660  -0.695  -0.695  -0.695  -0.660  -0.660  -0.660
315   R        -0.660  -0.660  -0.660  -0.271  -0.271  -0.271  -0.660  -0.660  -0.660
316   Q        -0.660  -0.660  -0.660  -0.565  -0.565  -0.565  -0.660  -0.660  -0.660
317   F        -0.660  -0.660  -0.660  -0.285  -0.285  -0.285  -0.660  -0.660  -0.660
318   L         1.509   1.509   1.509   1.291   1.291   1.291   1.509   1.509   1.509
319   N        -0.660  -0.660  -0.660  -0.445  -0.445  -0.445  -0.660  -0.660  -0.660
320   E        -0.660  -0.660  -0.660  -1.035  -1.035  -1.035  -0.660  -0.660  -0.660
321   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
322   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
323   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
324   I         1.509   1.509   1.509   1.558   1.558   1.558   1.509   1.509   1.509
325   L        -0.660  -0.660  -0.660  -0.806  -0.806  -0.806  -0.660  -0.660  -0.660
326   P         1.509   1.509   1.509   1.642   1.642   1.642   1.509   1.509   1.509
327   K        -0.660  -0.660  -0.660  -0.565  -0.565  -0.565  -0.660  -0.660  -0.660
328   Q        -0.660  -0.660  -0.660  -0.798  -0.798  -0.798  -0.660  -0.660  -0.660
329   T        -0.660  -0.660  -0.660  -0.550  -0.550  -0.550  -0.660  -0.660  -0.660
330   W        -0.660  -0.660  -0.660  -0.165  -0.165  -0.165  -0.660  -0.660  -0.660
331   S        -0.660  -0.660  -0.660  -0.774  -0.774  -0.774  -0.660  -0.660  -0.660
332   T        -0.660  -0.660  -0.660  -0.695  -0.695  -0.695  -0.660  -0.660  -0.660
333   I        -0.660  -0.660  -0.660  -0.542  -0.542  -0.542  -0.660  -0.660  -0.660
334   Q         1.509   1.509   1.509   1.569   1.569   1.569   1.509   1.509   1.509
335   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
336   E        -0.660  -0.660  -0.660  -0.649  -0.649  -0.649  -0.660  -0.660  -0.660
337   E         1.509   1.509   1.509   1.193   1.193   1.193   1.509   1.509   1.509
338   S         1.509   1.509   1.509   1.356   1.356   1.356   1.509   1.509   1.509
339   L        -0.660  -0.660  -0.660  -0.798  -0.798  -0.798  -0.660  -0.660  -0.660
340   N         1.509   1.509   1.509   1.537   1.537   1.537   1.509   1.509   1.509
341   I        -0.660  -0.660  -0.660  -0.878  -0.878  -0.878  -0.660  -0.660  -0.660
342   M        -0.660  -0.660  -0.660  -0.379  -0.379  -0.379  -0.660  -0.660  -0.660
343   D         1.509   1.509   1.509   1.421   1.421   1.421   1.509   1.509   1.509
344   F        -0.660  -0.660  -0.660  -0.207  -0.207  -0.207  -0.660  -0.660  -0.660
345   L        -0.660  -0.660  -0.660  -0.774  -0.774  -0.774  -0.660  -0.660  -0.660
346   K        -0.660  -0.660  -0.660  -0.512  -0.512  -0.512  -0.660  -0.660  -0.660
347   Q        -0.660  -0.660  -0.660  -0.798  -0.798  -0.798  -0.660  -0.660  -0.660
348   K        -0.660  -0.660  -0.660  -0.588  -0.588  -0.588  -0.660  -0.660  -0.660
349   I        -0.660  -0.660  -0.660  -0.542  -0.542  -0.542  -0.660  -0.660  -0.660
350   G        -0.660  -0.660  -0.660  -0.445  -0.445  -0.445  -0.660  -0.660  -0.660
351   T        -0.660  -0.660  -0.660  -0.336  -0.336  -0.336  -0.660  -0.660  -0.660
352   L        -0.660  -0.660  -0.660  -0.656  -0.656  -0.656  -0.660  -0.660  -0.660
353   Q        -0.660  -0.660  -0.660  -0.618  -0.618  -0.618  -0.660  -0.660  -0.660
354   K        -0.660  -0.660  -0.660  -0.505  -0.505  -0.505  -0.660  -0.660  -0.660
355   Q        -0.660  -0.660  -0.660  -0.565  -0.565  -0.565  -0.660  -0.660  -0.660
356   E        -0.660  -0.660  -0.660  -0.985  -0.985  -0.985  -0.660  -0.660  -0.660
357   L        -0.660  -0.660  -0.660  -0.572  -0.572  -0.572  -0.660  -0.660  -0.660
358   V        -0.660  -0.660  -0.660  -0.734  -0.734  -0.734  -0.660  -0.660  -0.660
359   D        -0.660  -0.660  -0.660  -0.641  -0.641  -0.641  -0.660  -0.660  -0.660
360   S        -0.660  -0.660  -0.660  -0.726  -0.726  -0.726  -0.660  -0.660  -0.660
361   F        -0.660  -0.660  -0.660  -0.214  -0.214  -0.214  -0.660  -0.660  -0.660
362   I        -0.660  -0.660  -0.660  -0.626  -0.626  -0.626  -0.660  -0.660  -0.660
363   D        -0.660  -0.660  -0.660  -0.910  -0.910  -0.910  -0.660  -0.660  -0.660
364   M        -0.660  -0.660  -0.660  -0.110  -0.110  -0.110  -0.660  -0.660  -0.660
365   G        -0.660  -0.660  -0.660  -0.401  -0.401  -0.401  -0.660  -0.660  -0.660
366   I        -0.660  -0.660  -0.660  -0.758  -0.758  -0.758  -0.660  -0.660  -0.660
367   I        -0.660  -0.660  -0.660  -0.711  -0.711  -0.711  -0.660  -0.660  -0.660
368   N        -0.660  -0.660  -0.660  -0.336  -0.336  -0.336  -0.660  -0.660  -0.660
369   N        -0.660  -0.660  -0.660  -0.565  -0.565  -0.565  -0.660  -0.660  -0.660
370   V        -0.660  -0.660  -0.660  -0.505  -0.505  -0.505  -0.660  -0.660  -0.660
371   D        -0.660  -0.660  -0.660  -0.985  -0.985  -0.985  -0.660  -0.660  -0.660
372   D        -0.660  -0.660  -0.660  -0.703  -0.703  -0.703  -0.660  -0.660  -0.660
373   M        -0.660  -0.660  -0.660  -0.321  -0.321  -0.321  -0.660  -0.660  -0.660
374   F         1.509   1.509   1.509   1.815   1.815   1.815   1.509   1.509   1.509
375   E         1.509   1.509   1.509   1.193   1.193   1.193   1.509   1.509   1.509
376   L        -0.660  -0.660  -0.660  -0.742  -0.742  -0.742  -0.660  -0.660  -0.660
377   A         1.509   1.509   1.509   1.754   1.754   1.754   1.509   1.509   1.509
378   H        -0.660  -0.660  -0.660  -0.096  -0.096  -0.096  -0.660  -0.660  -0.660
379   E        -0.660  -0.660  -0.660  -0.894  -0.894  -0.894  -0.660  -0.660  -0.660
380   L        -0.660  -0.660  -0.660  -0.580  -0.580  -0.580  -0.660  -0.660  -0.660
381   L         1.509   1.509   1.509   1.291   1.291   1.291   1.509   1.509   1.509
382   P        -0.660  -0.660  -0.660  -0.490  -0.490  -0.490  -0.660  -0.660  -0.660
383   L         1.509   1.509   1.509   1.291   1.291   1.291   1.509   1.509   1.509
384   E         1.509   1.509   1.509   1.193   1.193   1.193   1.509   1.509   1.509
385   L        -0.660  -0.660  -0.660  -0.798  -0.798  -0.798  -0.660  -0.660  -0.660
386   Q        -0.660  -0.660  -0.660  -0.314  -0.314  -0.314  -0.660  -0.660  -0.660
387   S        -0.660  -0.660  -0.660  -0.774  -0.774  -0.774  -0.660  -0.660  -0.660
388   R        -0.660  -0.660  -0.660  -0.774  -0.774  -0.774  -0.660  -0.660  -0.660
389   I        -0.660  -0.660  -0.660  -0.806  -0.806  -0.806  -0.660  -0.660  -0.660
390   E         1.509   1.509   1.509   1.193   1.193   1.193   1.509   1.509   1.509
391   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
392   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
393   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
394   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
395   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
396   S        -0.660  -0.660  -0.660  -1.035  -1.035  -1.035  -0.660  -0.660  -0.660
397   Y        -0.660  -0.660  -0.660  -0.214  -0.214  -0.214  -0.660  -0.660  -0.660
398   L         1.509   1.509   1.509   1.291   1.291   1.291   1.509   1.509   1.509
399   F        -0.660  -0.660  -0.660  -0.416  -0.416  -0.416  -0.660  -0.660  -0.660
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P43618
Output conservation file - output/P43618
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
