1     M         2.195   2.199   2.263   2.544   2.551   2.658   2.472   2.478   2.579
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    P        -1.180  -1.179  -1.153  -1.297  -1.304  -1.253  -0.983  -0.982  -0.935
34    Q        -0.336  -0.315  -0.343  -0.044  -0.006  -0.055  -0.407  -0.378  -0.409
35    N         0.826   0.839   0.763   1.004   1.024   0.921   0.744   0.765   0.622
36    K         0.826   0.802   0.756   0.930   0.896   0.837   0.744   0.702   0.609
37    I         0.508   0.509   0.555   0.213   0.216   0.284   0.169   0.171   0.236
38    L         2.195   2.199   2.263   2.031   2.034   2.135   2.472   2.478   2.579
39    V         0.508   0.510   0.555   0.213   0.215   0.283   0.169   0.171   0.237
40    L         0.826   0.824   0.765   0.661   0.656   0.562   0.744   0.740   0.624
41    S        -1.180  -1.179  -1.153  -1.040  -1.034  -0.992  -0.983  -0.982  -0.935
42    D        -0.479  -0.478  -0.444  -0.832  -0.830  -0.780  -0.599  -0.597  -0.545
43    H        -0.336  -0.325  -0.346   0.092   0.111   0.090  -0.407  -0.391  -0.414
44    P        -0.336  -0.338  -0.352  -0.467  -0.473  -0.473  -0.407  -0.411  -0.422
45    H         0.826   0.849   0.772   0.977   1.010   0.908   0.744   0.783   0.638
46    N        -1.180  -1.179  -1.153  -1.025  -1.017  -0.976  -0.983  -0.982  -0.935
47    F        -1.180  -1.179  -1.153  -1.387  -1.390  -1.345  -0.983  -0.982  -0.935
48    L        -0.336  -0.331  -0.349  -0.551  -0.543  -0.571  -0.407  -0.401  -0.417
49    K        -0.336  -0.315  -0.343  -0.093  -0.054  -0.106  -0.407  -0.378  -0.409
50    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
57    T        -1.180  -1.179  -1.153  -1.210  -1.208  -1.165  -0.983  -0.982  -0.935
58    Q        -0.336  -0.345  -0.356  -0.257  -0.278  -0.303  -0.407  -0.419  -0.428
59    F        -0.336  -0.354  -0.357  -0.445  -0.485  -0.516  -0.407  -0.431  -0.428
60    L         0.508   0.510   0.555   0.017   0.019   0.086   0.169   0.171   0.237
61    Q        -1.180  -1.179  -1.153  -0.991  -0.986  -0.942  -0.983  -0.982  -0.935
62    D        -0.336  -0.338  -0.352  -0.260  -0.260  -0.298  -0.407  -0.411  -0.422
63    L        -0.336  -0.331  -0.349  -0.603  -0.596  -0.629  -0.407  -0.401  -0.417
64    F         0.826   0.802   0.756   0.916   0.874   0.772   0.744   0.702   0.609
65    H        -1.180  -1.179  -1.153  -0.859  -0.864  -0.807  -0.983  -0.982  -0.935
66    C        -0.336  -0.315  -0.343  -0.180  -0.148  -0.181  -0.407  -0.378  -0.409
67    S        -0.336  -0.338  -0.352  -0.339  -0.349  -0.386  -0.407  -0.411  -0.422
68    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
69    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
70    S        -0.336  -0.331  -0.349  -0.521  -0.513  -0.568  -0.407  -0.401  -0.417
71    T        -0.336  -0.354  -0.357  -0.047  -0.070  -0.067  -0.407  -0.431  -0.428
72    G        -0.336  -0.345  -0.356  -0.242  -0.259  -0.301  -0.407  -0.419  -0.428
73    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
74    S        -0.336  -0.354  -0.357  -0.200  -0.226  -0.223  -0.407  -0.431  -0.428
75    I         0.826   0.802   0.756   0.639   0.597   0.502   0.744   0.702   0.609
76    V        -0.336  -0.345  -0.356  -0.296  -0.314  -0.332  -0.407  -0.419  -0.428
77    K        -0.336  -0.345  -0.356  -0.254  -0.269  -0.276  -0.407  -0.419  -0.428
78    D        -0.336  -0.354  -0.357  -0.416  -0.445  -0.444  -0.407  -0.431  -0.428
79    Q        -1.180  -1.179  -1.153  -1.095  -1.093  -1.047  -0.983  -0.982  -0.935
80    T        -0.336  -0.315  -0.343  -0.206  -0.174  -0.209  -0.407  -0.378  -0.409
81    W         0.826   0.802   0.756   1.111   1.069   0.972   0.744   0.702   0.609
82    E        -1.180  -1.179  -1.153  -1.276  -1.265  -1.232  -0.983  -0.982  -0.935
83    N         0.826   0.849   0.772   1.024   1.062   0.937   0.744   0.783   0.638
84    R         0.826   0.849   0.772   0.919   0.952   0.847   0.744   0.783   0.638
85    Y         2.195   2.199   2.263   2.470   2.477   2.582   2.472   2.478   2.579
86    Y         2.195   2.199   2.263   2.470   2.477   2.582   2.472   2.478   2.579
87    K        -1.180  -1.179  -1.153  -1.134  -1.125  -1.087  -0.983  -0.982  -0.935
88    V        -0.336  -0.345  -0.356  -0.351  -0.371  -0.394  -0.407  -0.419  -0.428
89    H        -1.180  -1.179  -1.153  -1.095  -1.101  -1.047  -0.983  -0.982  -0.935
90    F        -0.336  -0.325  -0.346  -0.382  -0.367  -0.381  -0.407  -0.391  -0.414
91    D         0.826   0.802   0.756   0.751   0.714   0.639   0.744   0.702   0.609
92    L         0.826   0.802   0.756   0.596   0.553   0.465   0.744   0.702   0.609
93    Y         0.826   0.802   0.756   1.006   0.964   0.867   0.744   0.702   0.609
94    I         0.826   0.824   0.765   0.725   0.723   0.626   0.744   0.740   0.624
95    D         2.195   2.199   2.263   2.118   2.124   2.224   2.472   2.478   2.579
96    S        -0.336  -0.315  -0.343  -0.534  -0.506  -0.536  -0.407  -0.378  -0.409
97    C         0.508   0.510   0.555   0.708   0.712   0.787   0.169   0.171   0.237
98    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
99    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
100   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
101   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
102   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
103   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
104   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
105   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
106   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
107   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
108   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
109   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
110   K        -1.180  -1.179  -1.153  -1.218  -1.215  -1.173  -0.983  -0.982  -0.935
111   E        -0.336  -0.331  -0.349  -0.660  -0.654  -0.683  -0.407  -0.401  -0.417
112   I         0.508   0.510   0.555   0.017   0.018   0.085   0.169   0.171   0.237
113   P        -0.336  -0.315  -0.343   0.053   0.089   0.051  -0.407  -0.378  -0.409
114   V        -1.180  -1.179  -1.153  -1.170  -1.168  -1.124  -0.983  -0.982  -0.935
115   W         2.195   2.199   2.263   2.578   2.586   2.692   2.472   2.478   2.579
116   V        -0.336  -0.354  -0.357  -0.320  -0.348  -0.359  -0.407  -0.431  -0.428
117   E        -0.336  -0.338  -0.352  -0.370  -0.366  -0.408  -0.407  -0.411  -0.422
118   E         0.826   0.839   0.763   0.530   0.549   0.414   0.744   0.765   0.622
119   F         0.826   0.824   0.765   1.019   1.018   0.918   0.744   0.740   0.624
120   I        -1.180  -1.179  -1.153  -1.214  -1.210  -1.169  -0.983  -0.982  -0.935
121   T         0.826   0.849   0.772   0.934   0.969   0.855   0.744   0.783   0.638
122   P        -0.336  -0.338  -0.352  -0.480  -0.492  -0.507  -0.407  -0.411  -0.422
123   E         0.826   0.824   0.765   0.530   0.525   0.417   0.744   0.740   0.624
124   C        -0.336  -0.354  -0.357   0.095   0.067   0.065  -0.407  -0.431  -0.428
125   E        -0.336  -0.345  -0.356  -0.505  -0.515  -0.521  -0.407  -0.419  -0.428
126   P         0.826   0.849   0.772   0.668   0.699   0.600   0.744   0.783   0.638
127   L         2.195   2.199   2.263   2.031   2.034   2.135   2.472   2.478   2.579
128   R         2.195   2.199   2.263   2.497   2.505   2.609   2.472   2.478   2.579
129   N        -0.336  -0.338  -0.352  -0.580  -0.591  -0.620  -0.407  -0.411  -0.422
130   V         0.826   0.824   0.765   0.830   0.827   0.708   0.744   0.740   0.624
131   M        -0.336  -0.315  -0.343  -0.483  -0.456  -0.487  -0.407  -0.378  -0.409
132   A        -1.180  -1.179  -1.153  -1.021  -1.026  -0.973  -0.983  -0.982  -0.935
133   G         0.826   0.824   0.765   1.204   1.201   1.122   0.744   0.740   0.624
134   I         0.826   0.802   0.756   0.639   0.597   0.502   0.744   0.702   0.609
135   I         0.826   0.802   0.756   0.811   0.779   0.722   0.744   0.702   0.609
136   L        -0.336  -0.325  -0.346  -0.385  -0.361  -0.425  -0.407  -0.391  -0.414
137   I        -0.336  -0.338  -0.352  -0.324  -0.321  -0.355  -0.407  -0.411  -0.422
138   T        -1.180  -1.179  -1.153  -0.946  -0.949  -0.896  -0.983  -0.982  -0.935
139   D        -1.180  -1.179  -1.153  -1.210  -1.206  -1.165  -0.983  -0.982  -0.935
140   I        -1.180  -1.179  -1.153  -1.071  -1.058  -1.023  -0.983  -0.982  -0.935
141   R        -1.180  -1.179  -1.153  -1.276  -1.279  -1.232  -0.983  -0.982  -0.935
142   Q        -1.180  -1.179  -1.153  -1.056  -1.052  -1.008  -0.983  -0.982  -0.935
143   T        -0.336  -0.345  -0.356  -0.162  -0.181  -0.196  -0.407  -0.419  -0.428
144   K        -0.336  -0.354  -0.357  -0.302  -0.331  -0.330  -0.407  -0.431  -0.428
145   P        -0.336  -0.354  -0.357  -0.245  -0.281  -0.306  -0.407  -0.431  -0.428
146   -        -0.479  -0.479  -0.444  -0.322  -0.323  -0.261  -0.599  -0.598  -0.545
147   -        -0.479  -0.479  -0.444  -0.507  -0.503  -0.449  -0.599  -0.598  -0.545
148   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
149   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
150   -         0.646   0.638   0.646   0.185   0.170   0.165   0.425   0.410   0.408
151   -        -0.479  -0.479  -0.444  -0.099  -0.098  -0.034  -0.599  -0.598  -0.545
152   Q        -0.336  -0.325  -0.346  -0.457  -0.443  -0.464  -0.407  -0.391  -0.414
153   E        -0.336  -0.331  -0.349  -0.617  -0.611  -0.635  -0.407  -0.401  -0.417
154   L        -1.180  -1.179  -1.153  -1.327  -1.325  -1.283  -0.983  -0.982  -0.935
155   L         0.826   0.802   0.756   0.596   0.553   0.465   0.744   0.702   0.609
156   H        -1.180  -1.179  -1.153  -1.126  -1.133  -1.079  -0.983  -0.982  -0.935
157   Q         0.508   0.509   0.555   0.313   0.317   0.387   0.169   0.171   0.236
158   F        -0.336  -0.345  -0.356  -0.416  -0.434  -0.483  -0.407  -0.419  -0.428
159   M        -1.180  -1.179  -1.153  -0.961  -0.967  -0.911  -0.983  -0.982  -0.935
160   I         0.826   0.824   0.765   0.762   0.761   0.673   0.744   0.740   0.624
161   A        -1.180  -1.179  -1.153  -1.044  -1.044  -0.996  -0.983  -0.982  -0.935
162   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
163   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
164   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
165   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
166   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
167   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
168   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
169   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
170   A        -0.336  -0.325  -0.346  -0.354  -0.338  -0.360  -0.407  -0.391  -0.414
171   H        -1.180  -1.179  -1.153  -0.746  -0.742  -0.692  -0.983  -0.982  -0.935
172   R        -1.180  -1.179  -1.153  -0.791  -0.788  -0.738  -0.983  -0.982  -0.935
173   N        -1.180  -1.179  -1.153  -0.866  -0.862  -0.814  -0.983  -0.982  -0.935
174   T        -1.180  -1.179  -1.153  -0.991  -0.987  -0.942  -0.983  -0.982  -0.935
175   F         0.508   0.510   0.555   0.297   0.297   0.366   0.169   0.172   0.237
176   V        -1.180  -1.179  -1.153  -0.931  -0.926  -0.881  -0.983  -0.982  -0.935
177   V         0.826   0.839   0.763   0.850   0.873   0.731   0.744   0.765   0.622
178   L        -1.180  -1.179  -1.153  -1.087  -1.084  -1.039  -0.983  -0.982  -0.935
179   A        -1.180  -1.179  -1.153  -0.650  -0.648  -0.595  -0.983  -0.982  -0.935
180   N        -0.336  -0.345  -0.356  -0.206  -0.222  -0.233  -0.407  -0.419  -0.428
181   V        -1.180  -1.179  -1.153  -0.855  -0.847  -0.803  -0.983  -0.982  -0.935
182   N        -0.336  -0.354  -0.357  -0.107  -0.129  -0.122  -0.407  -0.431  -0.428
183   E         0.826   0.824   0.765   0.661   0.658   0.581   0.744   0.740   0.624
184   E        -0.336  -0.325  -0.346  -0.370  -0.344  -0.397  -0.407  -0.391  -0.414
185   V         0.826   0.802   0.756   0.948   0.914   0.843   0.744   0.702   0.609
186   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
187   Q        -0.479  -0.478  -0.444  -0.588  -0.591  -0.532  -0.599  -0.597  -0.545
188   D        -0.336  -0.345  -0.356  -0.525  -0.537  -0.565  -0.407  -0.419  -0.428
189   E         0.826   0.824   0.765   0.627   0.624   0.539   0.744   0.740   0.624
190   I        -1.180  -1.179  -1.153  -1.370  -1.366  -1.327  -0.983  -0.982  -0.935
191   D         2.195   2.199   2.263   2.118   2.124   2.224   2.472   2.478   2.579
192   E         0.826   0.802   0.756   0.500   0.457   0.363   0.744   0.702   0.609
193   L        -0.336  -0.354  -0.357  -0.551  -0.582  -0.583  -0.407  -0.431  -0.428
194   N        -0.336  -0.315  -0.343  -0.426  -0.398  -0.425  -0.407  -0.378  -0.409
195   E         2.195   2.199   2.263   1.957   1.962   2.060   2.472   2.478   2.579
196   I         0.508   0.509   0.555   0.017   0.018   0.085   0.169   0.171   0.236
197   W        -1.180  -1.179  -1.153  -1.182  -1.193  -1.136  -0.983  -0.982  -0.935
198   S        -0.336  -0.354  -0.357  -0.299  -0.332  -0.334  -0.407  -0.431  -0.428
199   N        -0.479  -0.479  -0.444  -0.439  -0.432  -0.379  -0.599  -0.598  -0.545
200   A        -0.479  -0.479  -0.444  -0.525  -0.522  -0.467  -0.599  -0.598  -0.545
201   F         0.646   0.656   0.652   0.412   0.427   0.420   0.425   0.443   0.418
202   T        -0.479  -0.479  -0.444  -0.399  -0.398  -0.339  -0.599  -0.598  -0.545
203   N        -0.336  -0.325  -0.346  -0.195  -0.173  -0.214  -0.407  -0.391  -0.414
204   V        -1.180  -1.179  -1.153  -0.957  -0.951  -0.907  -0.983  -0.982  -0.935
205   I        -0.336  -0.345  -0.356  -0.521  -0.542  -0.559  -0.407  -0.419  -0.428
206   E         2.195   2.199   2.263   1.957   1.962   2.060   2.472   2.478   2.579
207   F         0.826   0.839   0.763   0.959   0.982   0.840   0.744   0.765   0.622
208   V         0.508   0.510   0.555   0.213   0.215   0.282   0.169   0.172   0.237
209   N         2.195   2.199   2.263   2.303   2.311   2.413   2.472   2.478   2.579
210   W        -0.336  -0.354  -0.357  -0.073  -0.110  -0.120  -0.407  -0.431  -0.428
211   K        -1.180  -1.179  -1.153  -0.928  -0.926  -0.877  -0.983  -0.982  -0.935
212   R        -0.336  -0.338  -0.352  -0.296  -0.299  -0.303  -0.407  -0.411  -0.422
213   S        -1.180  -1.179  -1.153  -1.413  -1.422  -1.372  -0.983  -0.982  -0.935
214   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
215   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   N        -0.479  -0.478  -0.444  -0.434  -0.426  -0.374  -0.599  -0.597  -0.545
219   H        -0.336  -0.315  -0.343  -0.363  -0.339  -0.350  -0.407  -0.378  -0.409
220   N        -0.336  -0.331  -0.349  -0.379  -0.369  -0.412  -0.407  -0.401  -0.417
221   D        -0.336  -0.315  -0.343  -0.551  -0.520  -0.554  -0.407  -0.378  -0.409
222   Y        -0.336  -0.331  -0.349  -0.096  -0.086  -0.117  -0.407  -0.401  -0.417
223   G        -1.180  -1.179  -1.153  -0.848  -0.854  -0.796  -0.983  -0.982  -0.935
224   E         0.826   0.839   0.763   0.530   0.549   0.414   0.744   0.765   0.622
225   K         0.826   0.824   0.765   0.955   0.952   0.881   0.744   0.740   0.624
226   L        -1.180  -1.179  -1.153  -1.194  -1.186  -1.148  -0.983  -0.982  -0.935
227   G         2.195   2.199   2.263   2.510   2.516   2.623   2.472   2.478   2.579
228   L        -1.180  -1.179  -1.153  -1.118  -1.115  -1.071  -0.983  -0.982  -0.935
229   D        -0.336  -0.331  -0.349  -0.505  -0.495  -0.531  -0.407  -0.401  -0.417
230   R         2.195   2.199   2.263   2.497   2.505   2.609   2.472   2.478   2.579
231   I         0.826   0.824   0.765   0.639   0.635   0.518   0.744   0.740   0.624
232   Q        -0.336  -0.338  -0.352  -0.296  -0.301  -0.316  -0.407  -0.411  -0.422
233   E         2.195   2.199   2.263   1.957   1.962   2.060   2.472   2.478   2.579
234   I         0.826   0.802   0.756   0.639   0.597   0.502   0.744   0.702   0.609
235   I         2.195   2.199   2.263   2.097   2.103   2.202   2.472   2.478   2.579
236   D         0.826   0.802   0.756   0.637   0.593   0.493   0.744   0.702   0.609
237   T        -0.336  -0.345  -0.356  -0.200  -0.215  -0.239  -0.407  -0.419  -0.428
238   H         2.195   2.199   2.263   2.531   2.539   2.644   2.472   2.478   2.579
239   D         0.508   0.509   0.555   0.400   0.403   0.473   0.169   0.171   0.236
240   W         2.195   2.199   2.263   2.578   2.586   2.692   2.472   2.478   2.579
241   L         0.508   0.510   0.555   0.250   0.259   0.328   0.169   0.172   0.237
242   N        -0.336  -0.331  -0.349  -0.357  -0.349  -0.388  -0.407  -0.401  -0.417
243   C        -0.336  -0.345  -0.356  -0.025  -0.046  -0.068  -0.407  -0.419  -0.428
244   E        -0.336  -0.331  -0.349  -0.502  -0.497  -0.508  -0.407  -0.401  -0.417
245   V        -0.336  -0.345  -0.356  -0.317  -0.325  -0.356  -0.407  -0.419  -0.428
246   Q        -1.180  -1.179  -1.153  -1.095  -1.101  -1.047  -0.983  -0.982  -0.935
247   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
248   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
249   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
250   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
251   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
252   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
253   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
254   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
255   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
256   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
257   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
258   P         0.826   0.849   0.772   0.739   0.770   0.671   0.744   0.783   0.638
259   A         0.508   0.509   0.555   0.435   0.439   0.511   0.169   0.171   0.236
260   T        -0.336  -0.325  -0.346  -0.290  -0.273  -0.300  -0.407  -0.391  -0.414
261   K        -0.336  -0.345  -0.356  -0.227  -0.237  -0.246  -0.407  -0.419  -0.428
262   I        -0.336  -0.315  -0.343  -0.617  -0.584  -0.626  -0.407  -0.378  -0.409
263   R        -0.336  -0.315  -0.343  -0.119  -0.091  -0.113  -0.407  -0.378  -0.409
264   E        -1.180  -1.179  -1.153  -0.991  -0.978  -0.942  -0.983  -0.982  -0.935
265   E        -1.180  -1.179  -1.153  -1.427  -1.421  -1.385  -0.983  -0.982  -0.935
266   I        -1.180  -1.179  -1.153  -1.210  -1.202  -1.165  -0.983  -0.982  -0.935
267   P        -0.336  -0.315  -0.343  -0.327  -0.294  -0.335  -0.407  -0.378  -0.409
268   N        -1.180  -1.179  -1.153  -1.222  -1.228  -1.177  -0.983  -0.982  -0.935
269   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
270   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
271   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
272   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
273   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
274   E        -0.336  -0.331  -0.349  -0.502  -0.497  -0.508  -0.407  -0.401  -0.417
275   M        -1.180  -1.179  -1.153  -1.052  -1.058  -1.004  -0.983  -0.982  -0.935
276   P         0.826   0.849   0.772   0.823   0.856   0.754   0.744   0.783   0.638
277   L         2.195   2.199   2.263   2.031   2.034   2.135   2.472   2.478   2.579
278   E         0.508   0.510   0.555  -0.022  -0.019   0.048   0.169   0.171   0.237
279   Q        -1.180  -1.179  -1.153  -1.018  -1.021  -0.969  -0.983  -0.982  -0.935
280   I        -0.336  -0.331  -0.349  -0.521  -0.516  -0.546  -0.407  -0.401  -0.417
281   I        -0.336  -0.345  -0.356  -0.293  -0.305  -0.303  -0.407  -0.419  -0.428
282   R        -1.180  -1.179  -1.153  -1.002  -1.006  -0.953  -0.983  -0.982  -0.935
283   N        -0.336  -0.325  -0.346  -0.290  -0.271  -0.300  -0.407  -0.391  -0.414
284   L         2.195   2.199   2.263   2.031   2.034   2.135   2.472   2.478   2.579
285   Q        -1.180  -1.179  -1.153  -1.226  -1.224  -1.181  -0.983  -0.982  -0.935
286   S        -1.180  -1.179  -1.153  -1.202  -1.209  -1.156  -0.983  -0.982  -0.935
287   A         2.195   2.199   2.263   2.463   2.471   2.575   2.472   2.478   2.579
288   R         0.508   0.509   0.555   0.460   0.464   0.537   0.169   0.171   0.236
289   L        -1.180  -1.179  -1.153  -1.655  -1.653  -1.617  -0.983  -0.982  -0.935
290   K        -0.336  -0.315  -0.343  -0.025   0.014  -0.034  -0.407  -0.378  -0.409
291   Y         0.826   0.802   0.756   1.140   1.105   1.038   0.744   0.702   0.609
292   K         0.826   0.849   0.772   0.999   1.038   0.906   0.744   0.783   0.638
293   S        -0.336  -0.331  -0.349  -0.281  -0.275  -0.300  -0.407  -0.401  -0.417
294   I        -0.336  -0.315  -0.343  -0.551  -0.519  -0.562  -0.407  -0.378  -0.409
295   E        -1.180  -1.179  -1.153  -1.306  -1.295  -1.262  -0.983  -0.982  -0.935
296   N         0.646   0.642   0.642   0.517   0.510   0.487   0.425   0.418   0.401
297   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
298   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
299   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
300   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
301   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
302   S         0.826   0.802   0.756   0.934   0.898   0.830   0.744   0.702   0.609
303   S        -1.180  -1.179  -1.153  -1.413  -1.419  -1.372  -0.983  -0.982  -0.935
304   E         2.195   2.199   2.263   1.957   1.962   2.060   2.472   2.478   2.579
305   A         0.826   0.802   0.756   1.144   1.111   1.045   0.744   0.702   0.609
306   D         0.508   0.509   0.555  -0.022  -0.020   0.046   0.169   0.171   0.236
307   A        -1.180  -1.179  -1.153  -1.095  -1.095  -1.047  -0.983  -0.982  -0.935
308   F         0.826   0.802   0.756   1.077   1.043   0.976   0.744   0.702   0.609
309   A         0.826   0.839   0.763   1.019   1.042   0.900   0.744   0.765   0.622
310   N        -0.336  -0.331  -0.349  -0.534  -0.525  -0.586  -0.407  -0.401  -0.417
311   E        -0.336  -0.325  -0.346  -0.438  -0.415  -0.464  -0.407  -0.391  -0.414
312   M        -0.336  -0.345  -0.356  -0.151  -0.166  -0.202  -0.407  -0.419  -0.428
313   A         0.508   0.510   0.555   0.344   0.344   0.414   0.169   0.171   0.237
314   D        -0.336  -0.354  -0.357  -0.534  -0.569  -0.577  -0.407  -0.431  -0.428
315   E         0.826   0.824   0.765   0.530   0.525   0.417   0.744   0.740   0.624
316   L         0.508   0.510   0.555   0.017   0.021   0.087   0.169   0.172   0.237
317   S        -0.336  -0.354  -0.357  -0.308  -0.341  -0.344  -0.407  -0.431  -0.428
318   R        -0.336  -0.325  -0.346  -0.339  -0.323  -0.343  -0.407  -0.391  -0.414
319   Y        -1.180  -1.179  -1.153  -0.781  -0.780  -0.727  -0.983  -0.982  -0.935
320   L         0.826   0.839   0.763   0.596   0.614   0.478   0.744   0.765   0.622
321   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P43615
Output conservation file - output/P43615
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
