1     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
45    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
46    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
47    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
48    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
49    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
50    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    M         0.181   0.111   0.023   0.500   0.402   0.250   0.127   0.022  -0.109
53    K        -0.722  -0.684  -0.683  -0.973  -0.950  -0.898  -0.749  -0.706  -0.678
54    A        -1.174  -1.171  -1.156  -1.273  -1.276  -1.247  -0.968  -0.963  -0.918
55    R        -1.174  -1.174  -1.133  -0.976  -0.970  -0.915  -0.968  -0.965  -0.896
56    K        -0.722  -0.676  -0.690  -0.807  -0.770  -0.740  -0.749  -0.698  -0.685
57    S        -0.100  -0.093  -0.095  -0.320  -0.335  -0.297  -0.311  -0.308  -0.296
58    Q        -1.174  -1.169  -1.135  -1.058  -1.075  -1.012  -0.968  -0.961  -0.898
59    R         0.181   0.251   0.045   0.040   0.128  -0.166   0.127   0.229  -0.076
60    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
61    K         1.876   1.894   1.968   1.685   1.697   1.828   2.099   2.127   2.245
62    A        -0.156  -0.095  -0.118  -0.231  -0.100  -0.192  -0.366  -0.277  -0.316
63    G        -0.833  -0.821  -0.751  -0.959  -0.944  -0.835  -0.859  -0.842  -0.747
64    S        -0.156  -0.162  -0.123  -0.376  -0.407  -0.357  -0.366  -0.376  -0.324
65    K        -0.727  -0.681  -0.685  -0.800  -0.728  -0.749  -0.740  -0.684  -0.673
66    P        -0.100  -0.067  -0.094  -0.317  -0.274  -0.288  -0.311  -0.265  -0.294
67    N        -1.174  -1.179  -1.139  -1.168  -1.186  -1.094  -0.968  -0.970  -0.902
68    L        -0.722  -0.746  -0.707  -0.955  -0.960  -0.917  -0.749  -0.769  -0.703
69    I         0.522   0.536   0.609   0.144   0.179   0.278   0.127   0.147   0.252
70    Q         1.876   1.894   1.968   1.960   1.980   2.105   2.099   2.127   2.245
71    S        -0.552  -0.585  -0.620  -0.486  -0.537  -0.562  -0.530  -0.571  -0.598
72    K        -0.722  -0.696  -0.690  -0.949  -0.904  -0.890  -0.749  -0.718  -0.685
73    L         1.876   1.894   1.968   1.817   1.869   1.961   2.099   2.127   2.245
74    Q        -0.722  -0.754  -0.693  -0.708  -0.779  -0.665  -0.749  -0.777  -0.688
75    V        -0.722  -0.680  -0.684  -0.691  -0.615  -0.643  -0.749  -0.702  -0.680
76    N        -0.722  -0.746  -0.707  -0.733  -0.760  -0.723  -0.749  -0.769  -0.703
77    N        -0.100  -0.150  -0.100  -0.280  -0.349  -0.259  -0.311  -0.367  -0.299
78    G        -0.833  -0.825  -0.751  -0.967  -0.954  -0.843  -0.859  -0.846  -0.747
79    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
80    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
81    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
82    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
83    N        -1.625  -1.610  -1.546  -1.322  -1.312  -1.201  -1.187  -1.169  -1.079
84    K        -0.100  -0.067  -0.094  -0.264  -0.228  -0.258  -0.311  -0.265  -0.294
85    I        -0.722  -0.692  -0.693  -1.017  -0.954  -0.981  -0.749  -0.713  -0.688
86    V        -0.722  -0.684  -0.690  -0.838  -0.772  -0.788  -0.749  -0.706  -0.685
87    K         0.522   0.538   0.610   0.136   0.154   0.279   0.127   0.151   0.254
88    C         1.876   1.894   1.968   2.102   2.133   2.248   2.099   2.127   2.245
89    D        -0.552  -0.601  -0.621  -0.423  -0.524  -0.567  -0.530  -0.590  -0.600
90    K         0.522   0.538   0.610   0.136   0.154   0.279   0.127   0.151   0.254
91    C         1.876   1.894   1.968   2.102   2.133   2.248   2.099   2.127   2.245
92    E        -0.722  -0.692  -0.693  -0.650  -0.619  -0.604  -0.749  -0.713  -0.688
93    M         0.996   1.041   0.871   1.260   1.331   1.069   1.003   1.076   0.761
94    S         0.181   0.251   0.045   0.219   0.310  -0.029   0.127   0.229  -0.076
95    Y         1.876   1.894   1.968   2.021   2.058   2.167   2.099   2.127   2.245
96    S        -0.552  -0.598  -0.646  -0.505  -0.578  -0.620  -0.530  -0.586  -0.628
97    S        -0.722  -0.746  -0.683  -0.789  -0.841  -0.729  -0.749  -0.769  -0.679
98    T        -0.722  -0.751  -0.706  -0.589  -0.633  -0.558  -0.749  -0.774  -0.702
99    S        -0.552  -0.598  -0.646  -0.594  -0.651  -0.739  -0.530  -0.586  -0.628
100   I        -0.722  -0.746  -0.707  -0.861  -0.876  -0.810  -0.749  -0.769  -0.703
101   E        -1.625  -1.610  -1.546  -1.438  -1.410  -1.317  -1.187  -1.169  -1.079
102   D         1.876   1.894   1.968   2.004   2.028   2.150   2.099   2.127   2.245
103   R        -1.625  -1.610  -1.546  -1.678  -1.635  -1.559  -1.187  -1.169  -1.079
104   A        -1.174  -1.185  -1.154  -1.090  -1.135  -1.077  -0.968  -0.976  -0.916
105   I        -1.625  -1.610  -1.546  -1.506  -1.467  -1.386  -1.187  -1.169  -1.079
106   H         1.876   1.894   1.968   2.051   2.078   2.197   2.099   2.127   2.245
107   E        -0.100  -0.069  -0.091  -0.347  -0.313  -0.309  -0.311  -0.267  -0.285
108   K         0.181   0.118   0.026   0.040  -0.080  -0.197   0.127   0.032  -0.105
109   Y         0.996   0.893   0.850   1.253   1.129   1.068   1.003   0.824   0.722
110   H         1.876   1.894   1.968   2.051   2.078   2.197   2.099   2.127   2.245
111   T        -0.722  -0.749  -0.693  -0.606  -0.679  -0.557  -0.749  -0.772  -0.688
112   L        -0.100  -0.158  -0.113  -0.222  -0.284  -0.233  -0.311  -0.379  -0.317
113   Q        -0.722  -0.751  -0.706  -0.432  -0.483  -0.402  -0.749  -0.774  -0.702
114   L         0.522   0.537   0.609   0.171   0.236   0.304   0.127   0.149   0.251
115   H         0.996   1.028   0.871   1.101   1.147   0.946   1.003   1.055   0.760
116   G         1.876   1.894   1.968   1.905   1.922   2.049   2.099   2.127   2.245
117   R        -0.722  -0.746  -0.707  -0.802  -0.805  -0.780  -0.749  -0.769  -0.703
118   K        -0.722  -0.676  -0.690  -0.799  -0.752  -0.752  -0.749  -0.698  -0.685
119   W         1.876   1.894   1.968   2.088   2.116   2.235   2.099   2.127   2.245
120   S        -0.552  -0.598  -0.646  -0.621  -0.725  -0.776  -0.530  -0.586  -0.628
121   P        -0.722  -0.695  -0.689  -0.552  -0.508  -0.489  -0.749  -0.716  -0.684
122   N        -0.552  -0.489  -0.596  -0.647  -0.567  -0.728  -0.530  -0.450  -0.569
123   W        -0.552  -0.598  -0.646  -0.205  -0.301  -0.365  -0.530  -0.586  -0.628
124   G        -0.552  -0.598  -0.646  -0.348  -0.448  -0.483  -0.530  -0.586  -0.628
125   S        -1.174  -1.171  -1.156  -1.091  -1.081  -1.072  -0.968  -0.963  -0.918
126   I        -1.174  -1.177  -1.148  -1.090  -1.087  -1.039  -0.968  -0.969  -0.910
127   V         0.632   0.682   0.679   0.365   0.455   0.420   0.346   0.435   0.392
128   Y        -1.174  -1.171  -1.156  -1.018  -1.012  -0.975  -0.968  -0.963  -0.918
129   T        -0.833  -0.820  -0.751  -0.830  -0.827  -0.705  -0.859  -0.841  -0.747
130   E        -0.833  -0.820  -0.751  -0.916  -0.908  -0.791  -0.859  -0.841  -0.747
131   R         0.019   0.044  -0.050   0.169   0.210   0.053  -0.110  -0.072  -0.217
132   N        -0.727  -0.709  -0.691  -0.756  -0.726  -0.706  -0.740  -0.716  -0.681
133   H        -0.727  -0.702  -0.714  -0.555  -0.509  -0.564  -0.740  -0.708  -0.707
134   S        -0.727  -0.721  -0.692  -0.906  -0.897  -0.886  -0.740  -0.729  -0.681
135   R        -1.269  -1.263  -1.188  -1.286  -1.277  -1.165  -1.056  -1.045  -0.946
136   T        -0.727  -0.702  -0.714  -0.765  -0.725  -0.748  -0.740  -0.708  -0.707
137   V        -1.269  -1.263  -1.188  -1.207  -1.189  -1.085  -1.056  -1.045  -0.946
138   H        -0.156  -0.118  -0.121  -0.086  -0.030  -0.031  -0.366  -0.311  -0.321
139   L         0.522   0.536   0.609   0.333   0.356   0.471   0.127   0.147   0.252
140   S         0.522   0.537   0.610  -0.024  -0.008   0.109   0.127   0.149   0.255
141   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
142   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
143   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
144   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
145   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
146   I        -0.833  -0.825  -0.751  -0.815  -0.804  -0.690  -0.859  -0.846  -0.747
147   T        -0.156  -0.133  -0.117  -0.393  -0.353  -0.366  -0.366  -0.332  -0.315
148   P        -0.156  -0.160  -0.146  -0.109  -0.116  -0.091  -0.366  -0.372  -0.356
149   L        -0.156  -0.160  -0.146  -0.328  -0.340  -0.356  -0.366  -0.372  -0.356
150   N         0.777   0.764   0.738   0.517   0.492   0.442   0.620   0.589   0.508
151   S         0.019   0.030  -0.045  -0.093  -0.077  -0.196  -0.110  -0.094  -0.210
152   S        -0.727  -0.728  -0.711  -0.872  -0.881  -0.846  -0.740  -0.738  -0.704
153   P        -0.727  -0.728  -0.711  -0.777  -0.783  -0.793  -0.740  -0.738  -0.704
154   L        -0.727  -0.737  -0.710  -0.604  -0.627  -0.611  -0.740  -0.748  -0.702
155   K        -0.727  -0.728  -0.711  -0.926  -0.930  -0.889  -0.740  -0.738  -0.704
156   K         0.019   0.058  -0.047  -0.184  -0.126  -0.286  -0.110  -0.052  -0.212
157   S        -0.727  -0.710  -0.688  -0.765  -0.742  -0.696  -0.740  -0.717  -0.678
158   S        -0.185  -0.184  -0.140  -0.574  -0.571  -0.493  -0.425  -0.421  -0.354
159   P        -0.727  -0.718  -0.692  -0.760  -0.746  -0.730  -0.740  -0.726  -0.682
160   S        -0.185  -0.165  -0.133  -0.405  -0.379  -0.326  -0.425  -0.399  -0.347
161   I        -1.269  -1.263  -1.188  -1.169  -1.155  -1.047  -1.056  -1.045  -0.946
162   T        -1.269  -1.263  -1.188  -1.207  -1.201  -1.085  -1.056  -1.045  -0.946
163   H        -1.269  -1.263  -1.188  -1.137  -1.120  -1.014  -1.056  -1.045  -0.946
164   Q        -1.174  -1.171  -1.156  -1.055  -1.054  -0.999  -0.968  -0.963  -0.918
165   E        -0.727  -0.643  -0.689  -0.805  -0.701  -0.732  -0.740  -0.637  -0.678
166   E         0.898   0.816   0.799   0.972   0.834   0.794   0.837   0.686   0.626
167   K        -0.727  -0.680  -0.684  -0.814  -0.764  -0.736  -0.740  -0.682  -0.672
168   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
169   I         0.181   0.111   0.023   0.171   0.091  -0.074   0.127   0.022  -0.109
170   V        -0.552  -0.598  -0.646  -0.445  -0.500  -0.562  -0.530  -0.586  -0.628
171   Y        -0.722  -0.697  -0.692  -0.451  -0.430  -0.387  -0.749  -0.718  -0.687
172   V         0.632   0.603   0.643   0.362   0.321   0.346   0.346   0.282   0.320
173   R        -1.625  -1.610  -1.546  -1.326  -1.293  -1.204  -1.187  -1.169  -1.079
174   P        -0.722  -0.679  -0.689  -0.763  -0.727  -0.702  -0.749  -0.700  -0.684
175   D        -1.174  -1.111  -1.131  -1.198  -1.119  -1.129  -0.968  -0.901  -0.895
176   K        -0.552  -0.598  -0.646  -0.621  -0.699  -0.740  -0.530  -0.586  -0.628
177   S        -1.174  -1.174  -1.133  -1.242  -1.250  -1.179  -0.968  -0.965  -0.896
178   N        -1.174  -1.177  -1.148  -1.134  -1.143  -1.107  -0.968  -0.969  -0.910
179   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
180   E        -0.552  -0.598  -0.646  -0.315  -0.414  -0.467  -0.530  -0.586  -0.628
181   V         0.181   0.102   0.022   0.216   0.110  -0.013   0.127   0.009  -0.110
182   R        -0.552  -0.601  -0.621  -0.577  -0.649  -0.651  -0.530  -0.590  -0.600
183   A        -0.552  -0.598  -0.646  -0.374  -0.442  -0.525  -0.530  -0.586  -0.628
184   M        -0.100  -0.050  -0.096  -0.120  -0.062  -0.096  -0.311  -0.238  -0.293
185   T        -0.722  -0.751  -0.706  -0.746  -0.794  -0.727  -0.749  -0.774  -0.702
186   E        -0.552  -0.592  -0.618  -0.304  -0.366  -0.407  -0.530  -0.580  -0.595
187   I        -0.100  -0.157  -0.097  -0.235  -0.257  -0.208  -0.311  -0.376  -0.299
188   M         0.522   0.538   0.610   0.402   0.436   0.532   0.127   0.151   0.254
189   T        -1.174  -1.117  -1.133  -1.251  -1.194  -1.179  -0.968  -0.907  -0.897
190   L        -0.722  -0.695  -0.689  -0.799  -0.720  -0.729  -0.749  -0.716  -0.684
191   V         1.876   1.894   1.968   1.782   1.799   1.926   2.099   2.127   2.245
192   N         1.876   1.894   1.968   1.873   1.901   2.018   2.099   2.127   2.245
193   N        -1.174  -1.183  -1.136  -1.004  -1.055  -0.954  -0.968  -0.973  -0.899
194   E         1.876   1.894   1.968   1.973   1.996   2.119   2.099   2.127   2.245
195   L         1.876   1.894   1.968   1.817   1.869   1.961   2.099   2.127   2.245
196   N         1.876   1.894   1.968   1.873   1.901   2.018   2.099   2.127   2.245
197   A         1.876   1.894   1.968   1.925   1.942   2.070   2.099   2.127   2.245
198   P         0.181   0.221   0.026   0.360   0.427   0.108   0.127   0.186  -0.104
199   H        -0.185  -0.183  -0.139  -0.180  -0.179  -0.120  -0.425  -0.420  -0.353
200   D         1.876   1.894   1.968   2.002   2.029   2.147   2.099   2.127   2.245
201   E         0.019   0.004  -0.072   0.104   0.077  -0.075  -0.110  -0.132  -0.249
202   N         0.019   0.004  -0.072  -0.051  -0.079  -0.231  -0.110  -0.132  -0.249
203   V        -0.727  -0.719  -0.695  -0.661  -0.646  -0.622  -0.740  -0.728  -0.685
204   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
205   W         1.876   1.894   1.968   2.080   2.108   2.227   2.099   2.127   2.245
206   -        -0.833  -0.826  -0.751  -1.026  -1.016  -0.903  -0.859  -0.847  -0.747
207   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
208   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
209   N        -1.174  -1.179  -1.139  -0.973  -0.974  -0.932  -0.968  -0.970  -0.902
210   S        -1.174  -1.131  -1.130  -1.022  -0.944  -0.965  -0.968  -0.921  -0.893
211   T        -1.625  -1.610  -1.546  -1.580  -1.560  -1.461  -1.187  -1.169  -1.079
212   T        -0.727  -0.714  -0.695  -0.701  -0.695  -0.660  -0.740  -0.725  -0.685
213   E        -0.727  -0.756  -0.711  -0.764  -0.828  -0.772  -0.740  -0.772  -0.704
214   E        -1.174  -1.121  -1.129  -1.056  -0.991  -0.974  -0.968  -0.911  -0.893
215   K         0.181   0.217   0.052   0.331   0.376   0.117   0.127   0.180  -0.066
216   G         0.181   0.102   0.022   0.293   0.162   0.037   0.127   0.009  -0.110
217   K         0.181   0.111   0.023   0.090  -0.023  -0.125   0.127   0.022  -0.109
218   A         0.996   0.893   0.850   1.099   0.937   0.876   1.003   0.824   0.722
219   F         0.181   0.134   0.028   0.501   0.443   0.262   0.127   0.054  -0.102
220   V         0.632   0.669   0.663   0.365   0.432   0.389   0.346   0.410   0.361
221   Y         0.181   0.221   0.026   0.384   0.459   0.118   0.127   0.186  -0.104
222   I         0.522   0.536   0.609   0.144   0.180   0.278   0.127   0.149   0.252
223   R        -0.722  -0.751  -0.706  -0.980  -1.012  -0.941  -0.749  -0.774  -0.702
224   N         0.181   0.234   0.050   0.359   0.436   0.132   0.127   0.205  -0.069
225   D        -1.625  -1.610  -1.546  -1.524  -1.498  -1.404  -1.187  -1.169  -1.079
226   R         0.632   0.672   0.662   0.454   0.520   0.458   0.346   0.416   0.358
227   A         0.996   1.060   0.871   1.099   1.178   0.912   1.003   1.108   0.761
228   V         0.632   0.660   0.673   0.365   0.416   0.408   0.346   0.393   0.380
229   G         1.876   1.894   1.968   1.905   1.922   2.049   2.099   2.127   2.245
230   I        -1.174  -1.174  -1.133  -1.091  -1.040  -1.021  -0.968  -0.965  -0.896
231   I        -0.100  -0.158  -0.113  -0.158  -0.222  -0.170  -0.311  -0.379  -0.317
232   I         0.181   0.108   0.026   0.271   0.158   0.013   0.127   0.017  -0.105
233   I        -0.271  -0.259  -0.184  -0.548  -0.529  -0.420  -0.530  -0.513  -0.410
234   E         0.632   0.601   0.643   0.646   0.583   0.648   0.346   0.277   0.321
235   N        -1.625  -1.610  -1.546  -1.345  -1.318  -1.224  -1.187  -1.169  -1.079
236   L         0.632   0.675   0.679   0.378   0.490   0.436   0.346   0.423   0.391
237   Y        -0.727  -0.702  -0.714  -0.635  -0.590  -0.630  -0.740  -0.708  -0.707
238   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
239   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
240   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
241   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
242   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
243   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
244   S        -1.269  -1.263  -1.188  -1.101  -1.090  -0.977  -1.056  -1.045  -0.946
245   S        -1.625  -1.610  -1.546  -1.330  -1.329  -1.209  -1.187  -1.169  -1.079
246   R        -0.271  -0.259  -0.184  -0.488  -0.498  -0.370  -0.530  -0.513  -0.410
247   G         0.522   0.536   0.609   0.473   0.496   0.613   0.127   0.147   0.252
248   R         0.996   1.041   0.871   1.087   1.147   0.883   1.003   1.076   0.761
249   W         0.996   0.893   0.850   1.312   1.177   1.121   1.003   0.824   0.722
250   M         0.181   0.111   0.023   0.449   0.340   0.174   0.127   0.022  -0.109
251   V        -0.100  -0.155  -0.099  -0.280  -0.323  -0.259  -0.311  -0.374  -0.298
252   Y        -0.722  -0.746  -0.707  -0.566  -0.587  -0.559  -0.749  -0.769  -0.703
253   D        -1.174  -1.177  -1.148  -0.953  -0.971  -0.926  -0.968  -0.969  -0.910
254   S         0.996   1.028   0.871   1.061   1.093   0.867   1.003   1.055   0.760
255   R        -0.722  -0.746  -0.707  -0.697  -0.742  -0.688  -0.749  -0.769  -0.703
256   R        -0.722  -0.700  -0.683  -0.710  -0.698  -0.651  -0.749  -0.721  -0.679
257   L         0.632   0.664   0.663   0.398   0.489   0.420   0.346   0.400   0.360
258   V         0.996   0.893   0.850   0.981   0.828   0.778   1.003   0.824   0.722
259   Q        -0.552  -0.575  -0.624  -0.313  -0.346  -0.429  -0.530  -0.560  -0.603
260   N         0.181   0.134   0.028   0.274   0.181   0.035   0.127   0.054  -0.102
261   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
262   V         0.181   0.102   0.022   0.196   0.082  -0.043   0.127   0.009  -0.110
263   Y        -0.722  -0.676  -0.690  -0.643  -0.563  -0.586  -0.749  -0.698  -0.685
264   P         0.181   0.221   0.026   0.344   0.413   0.084   0.127   0.186  -0.104
265   D        -1.174  -1.177  -1.148  -0.933  -0.941  -0.903  -0.968  -0.969  -0.910
266   F        -0.100  -0.056  -0.079  -0.164  -0.104  -0.130  -0.311  -0.246  -0.268
267   K         0.019   0.032  -0.041  -0.187  -0.170  -0.280  -0.110  -0.091  -0.203
268   I        -0.100  -0.160  -0.099  -0.222  -0.249  -0.203  -0.311  -0.381  -0.302
269   G         1.876   1.894   1.968   1.905   1.922   2.049   2.099   2.127   2.245
270   I         0.996   0.893   0.850   0.949   0.826   0.729   1.003   0.824   0.722
271   S         1.876   1.894   1.968   1.728   1.743   1.872   2.099   2.127   2.245
272   R         1.876   1.894   1.968   1.939   1.962   2.084   2.099   2.127   2.245
273   I         0.996   0.893   0.850   1.012   0.910   0.835   1.003   0.824   0.722
274   W         0.996   0.893   0.850   1.306   1.172   1.111   1.003   0.824   0.722
275   V         0.632   0.660   0.673   0.365   0.416   0.408   0.346   0.393   0.380
276   C        -0.100  -0.099  -0.112  -0.053  -0.088  -0.099  -0.311  -0.318  -0.319
277   R         0.181   0.111   0.023   0.393   0.290   0.170   0.127   0.022  -0.109
278   T        -1.174  -1.171  -1.156  -1.248  -1.253  -1.199  -0.968  -0.963  -0.918
279   A        -0.722  -0.751  -0.706  -0.448  -0.482  -0.407  -0.749  -0.774  -0.702
280   R         1.876   1.894   1.968   1.939   1.962   2.084   2.099   2.127   2.245
281   K        -0.722  -0.681  -0.684  -0.697  -0.648  -0.646  -0.749  -0.703  -0.680
282   L        -1.174  -1.171  -1.156  -0.980  -0.967  -0.976  -0.968  -0.963  -0.918
283   G         1.876   1.894   1.968   1.905   1.922   2.049   2.099   2.127   2.245
284   I         0.632   0.660   0.673   0.378   0.462   0.424   0.346   0.393   0.380
285   A         0.181   0.102   0.022   0.321   0.180   0.067   0.127   0.009  -0.110
286   T        -0.552  -0.486  -0.608  -0.440  -0.357  -0.540  -0.530  -0.445  -0.584
287   K         0.632   0.669   0.663   0.317   0.361   0.360   0.346   0.410   0.361
288   L         1.876   1.894   1.968   1.817   1.869   1.961   2.099   2.127   2.245
289   I         0.996   1.028   0.871   0.990   1.067   0.802   1.003   1.055   0.760
290   D         0.181   0.228   0.056   0.435   0.500   0.250   0.127   0.196  -0.061
291   V        -0.552  -0.572  -0.614  -0.563  -0.595  -0.668  -0.530  -0.556  -0.590
292   A         0.632   0.660   0.673   0.502   0.536   0.542   0.346   0.393   0.380
293   R        -0.100  -0.158  -0.113  -0.220  -0.315  -0.269  -0.311  -0.379  -0.317
294   E        -1.174  -1.175  -1.137  -1.362  -1.381  -1.304  -0.968  -0.966  -0.900
295   N        -1.174  -1.169  -1.135  -1.090  -1.073  -1.036  -0.968  -0.961  -0.898
296   I        -0.552  -0.575  -0.624  -0.526  -0.552  -0.619  -0.530  -0.560  -0.603
297   V         0.632   0.663   0.657   0.362   0.437   0.375   0.346   0.399   0.349
298   Y         0.996   1.060   0.871   1.231   1.330   1.065   1.003   1.108   0.761
299   G         0.996   1.021   0.870   1.068   1.094   0.873   1.003   1.043   0.759
300   E        -1.625  -1.610  -1.546  -1.253  -1.208  -1.131  -1.187  -1.169  -1.079
301   V        -1.174  -1.174  -1.133  -1.106  -1.094  -1.038  -0.968  -0.965  -0.896
302   I        -0.100  -0.055  -0.096  -0.310  -0.203  -0.309  -0.311  -0.243  -0.294
303   P        -1.174  -1.187  -1.138  -0.909  -0.918  -0.859  -0.968  -0.978  -0.901
304   R         0.996   1.028   0.871   0.851   0.884   0.687   1.003   1.055   0.760
305   Y        -1.174  -1.111  -1.131  -0.926  -0.840  -0.852  -0.968  -0.901  -0.895
306   Q        -0.100  -0.040  -0.081  -0.115  -0.027  -0.096  -0.311  -0.229  -0.275
307   V        -0.100  -0.052  -0.078  -0.321  -0.225  -0.285  -0.311  -0.239  -0.268
308   A         0.996   1.033   0.869   1.123   1.163   0.947   1.003   1.062   0.757
309   W         0.522   0.538   0.610   0.590   0.613   0.728   0.127   0.151   0.254
310   S         0.996   0.893   0.850   0.926   0.770   0.723   1.003   0.824   0.722
311   Q         1.876   1.894   1.968   1.960   1.980   2.105   2.099   2.127   2.245
312   P         1.876   1.894   1.968   1.973   2.012   2.119   2.099   2.127   2.245
313   T         0.996   1.028   0.871   0.926   0.957   0.755   1.003   1.055   0.760
314   D        -0.722  -0.746  -0.707  -0.447  -0.485  -0.414  -0.749  -0.769  -0.703
315   S         0.996   0.893   0.850   0.927   0.773   0.725   1.003   0.824   0.722
316   G         1.876   1.894   1.968   1.905   1.922   2.049   2.099   2.127   2.245
317   G         0.181   0.118   0.026   0.267   0.164   0.004   0.127   0.032  -0.105
318   K        -0.552  -0.499  -0.614  -0.639  -0.553  -0.720  -0.530  -0.462  -0.591
319   L         0.996   0.893   0.850   0.991   0.865   0.770   1.003   0.824   0.722
320   A         1.876   1.894   1.968   1.925   1.942   2.070   2.099   2.127   2.245
321   S         0.181   0.108   0.026   0.049  -0.067  -0.184   0.127   0.017  -0.105
322   K        -0.100  -0.150  -0.100  -0.440  -0.516  -0.434  -0.311  -0.367  -0.299
323   Y        -0.100  -0.158  -0.113   0.114   0.052   0.121  -0.311  -0.379  -0.317
324   N         0.996   0.893   0.850   1.076   0.933   0.873   1.003   0.824   0.722
325   G         0.996   1.041   0.871   1.107   1.159   0.937   1.003   1.076   0.761
326   I        -0.552  -0.588  -0.621  -0.537  -0.601  -0.647  -0.530  -0.575  -0.599
327   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
328   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
329   M        -0.552  -0.593  -0.618  -0.610  -0.699  -0.689  -0.530  -0.581  -0.596
330   H         0.996   0.893   0.850   1.270   1.135   1.076   1.003   0.824   0.722
331   K         0.632   0.607   0.644   0.317   0.263   0.331   0.346   0.290   0.322
332   S         0.996   0.893   0.850   0.942   0.793   0.750   1.003   0.824   0.722
333   G         1.876   1.894   1.968   1.905   1.922   2.049   2.099   2.127   2.245
334   K        -0.100  -0.042  -0.097  -0.171  -0.085  -0.156  -0.311  -0.231  -0.296
335   L        -0.185  -0.184  -0.140  -0.369  -0.366  -0.280  -0.425  -0.421  -0.354
336   L         1.876   1.894   1.968   1.828   1.854   1.973   2.099   2.127   2.245
337   L         0.561   0.568   0.622   0.211   0.217   0.296   0.206   0.212   0.277
338   P         1.876   1.894   1.968   1.978   2.005   2.123   2.099   2.127   2.245
339   V         0.561   0.585   0.633   0.453   0.486   0.567   0.206   0.245   0.300
340   Y         1.876   1.894   1.968   2.033   2.061   2.179   2.099   2.127   2.245
341   I         0.561   0.575   0.625   0.211   0.229   0.303   0.206   0.226   0.285
342   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
343   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P43605
Output conservation file - output/P43605
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
