1     M         2.046   2.056   2.178   2.288   2.302   2.489   2.308   2.327   2.538
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     K         0.225   0.184   0.242   0.191   0.149   0.232  -0.077  -0.123  -0.047
6     L         0.995   1.026   0.980   0.759   0.805   0.695   0.801   0.857   0.699
7     K         0.995   0.949   0.975   0.928   0.859   0.874   0.801   0.706   0.689
8     V         0.225   0.252   0.236  -0.090  -0.055  -0.069  -0.077  -0.042  -0.050
9     T        -0.746  -0.738  -0.756  -0.713  -0.696  -0.732  -0.705  -0.702  -0.688
10    G        -0.869  -0.863  -0.814  -0.974  -0.955  -0.874  -0.831  -0.823  -0.745
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    A        -1.192  -1.167  -1.140  -1.012  -0.980  -0.936  -0.956  -0.935  -0.873
13    G        -0.545  -0.601  -0.689  -0.406  -0.499  -0.653  -0.454  -0.519  -0.607
14    I        -1.516  -1.514  -1.449  -1.458  -1.461  -1.377  -1.082  -1.080  -0.988
15    N        -0.423  -0.452  -0.376  -0.590  -0.617  -0.499  -0.580  -0.607  -0.511
16    Q        -0.746  -0.739  -0.740  -0.692  -0.683  -0.671  -0.705  -0.699  -0.672
17    V         0.364   0.347   0.311   0.310   0.306   0.236   0.174   0.164   0.085
18    V        -1.192  -1.167  -1.131  -1.345  -1.316  -1.265  -0.956  -0.935  -0.866
19    T        -0.221  -0.187  -0.281  -0.187  -0.156  -0.283  -0.329  -0.301  -0.395
20    L        -0.746  -0.694  -0.737  -0.857  -0.779  -0.857  -0.705  -0.652  -0.669
21    K        -0.746  -0.723  -0.743  -0.830  -0.791  -0.841  -0.705  -0.682  -0.675
22    Q        -0.746  -0.741  -0.729  -0.644  -0.638  -0.623  -0.705  -0.701  -0.661
23    D        -0.746  -0.722  -0.741  -0.720  -0.687  -0.702  -0.705  -0.685  -0.675
24    A        -0.746  -0.748  -0.739  -0.688  -0.695  -0.676  -0.705  -0.703  -0.671
25    T        -0.746  -0.748  -0.739  -0.863  -0.860  -0.882  -0.705  -0.703  -0.671
26    L         0.364   0.404   0.297   0.207   0.248   0.112   0.174   0.220   0.057
27    N        -0.869  -0.896  -0.800  -0.871  -0.891  -0.760  -0.831  -0.851  -0.733
28    D         0.364   0.369   0.293   0.282   0.294   0.148   0.174   0.188   0.048
29    L         0.810   0.831   0.896   0.523   0.555   0.646   0.425   0.464   0.519
30    I        -0.746  -0.737  -0.732  -0.838  -0.834  -0.805  -0.705  -0.699  -0.664
31    E        -1.516  -1.513  -1.466  -1.365  -1.366  -1.291  -1.082  -1.079  -1.001
32    H        -1.516  -1.505  -1.452  -1.295  -1.272  -1.180  -1.082  -1.073  -0.991
33    I         0.995   0.985   0.982   0.831   0.812   0.769   0.801   0.778   0.704
34    N        -1.516  -1.511  -1.450  -1.370  -1.360  -1.259  -1.082  -1.078  -0.989
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    -        -0.110  -0.115  -0.210  -0.173  -0.181  -0.340  -0.152  -0.162  -0.288
43    -        -0.850  -0.853  -0.796  -1.052  -1.056  -0.978  -0.808  -0.809  -0.726
44    -        -0.850  -0.867  -0.800  -0.902  -0.913  -0.796  -0.808  -0.821  -0.729
45    -        -0.850  -0.868  -0.791  -0.898  -0.923  -0.806  -0.808  -0.822  -0.722
46    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
47    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
48    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
49    D        -1.192  -1.190  -1.134  -1.173  -1.163  -1.071  -0.956  -0.952  -0.868
50    V        -1.070  -1.114  -1.106  -0.974  -1.049  -1.059  -0.831  -0.873  -0.838
51    K        -1.192  -1.159  -1.150  -1.090  -1.026  -1.031  -0.956  -0.929  -0.880
52    T        -0.423  -0.434  -0.377  -0.579  -0.616  -0.528  -0.580  -0.596  -0.513
53    M         0.024   0.039   0.131  -0.268  -0.253  -0.110  -0.329  -0.309  -0.193
54    R         0.810   0.827   0.909   0.621   0.653   0.761   0.425   0.454   0.547
55    F        -0.746  -0.712  -0.740  -0.542  -0.491  -0.544  -0.705  -0.675  -0.673
56    G         2.046   2.056   2.178   2.032   2.043   2.229   2.308   2.327   2.538
57    Y         0.810   0.802   0.895   0.788   0.771   0.899   0.425   0.403   0.516
58    P         2.046   2.056   2.178   2.164   2.177   2.363   2.308   2.327   2.538
59    P         1.342   1.277   1.200   1.519   1.429   1.309   1.429   1.318   1.145
60    Q         0.751   0.758   0.871   0.542   0.556   0.716   0.299   0.309   0.463
61    R        -1.192  -1.166  -1.143  -1.081  -1.051  -1.012  -0.956  -0.933  -0.876
62    I         0.671   0.610   0.446   0.696   0.609   0.351   0.676   0.582   0.311
63    N         0.040   0.054  -0.148   0.177   0.200  -0.102   0.048   0.067  -0.205
64    L        -0.221  -0.214  -0.268  -0.308  -0.315  -0.352  -0.329  -0.330  -0.381
65    Q        -0.221  -0.221  -0.277  -0.277  -0.277  -0.349  -0.329  -0.324  -0.388
66    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
67    G        -0.746  -0.752  -0.748  -0.621  -0.632  -0.604  -0.705  -0.716  -0.680
68    E        -0.746  -0.731  -0.750  -0.862  -0.824  -0.868  -0.705  -0.683  -0.679
69    D        -0.746  -0.788  -0.755  -0.780  -0.840  -0.798  -0.705  -0.745  -0.687
70    A        -1.070  -1.091  -1.094  -0.896  -0.934  -0.958  -0.831  -0.852  -0.827
71    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
72    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
73    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
74    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
75    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
76    Q        -0.746  -0.719  -0.735  -0.586  -0.539  -0.569  -0.705  -0.671  -0.667
77    L         2.046   2.056   2.178   1.890   1.904   2.085   2.308   2.327   2.538
78    D        -0.746  -0.773  -0.759  -0.874  -0.912  -0.890  -0.705  -0.730  -0.689
79    E        -0.221  -0.245  -0.287  -0.294  -0.331  -0.418  -0.329  -0.359  -0.403
80    L         0.671   0.726   0.460   0.652   0.724   0.352   0.676   0.757   0.333
81    G         0.558   0.533   0.394   0.631   0.583   0.378   0.504   0.459   0.227
82    I         0.364   0.316   0.278   0.192   0.106   0.019   0.174   0.095   0.023
83    N        -0.869  -0.848  -0.803  -0.840  -0.804  -0.721  -0.831  -0.812  -0.735
84    S        -0.341  -0.323  -0.318  -0.444  -0.427  -0.426  -0.480  -0.463  -0.442
85    G         2.046   2.056   2.178   2.032   2.043   2.229   2.308   2.327   2.538
86    E         0.225   0.226   0.233   0.050   0.064   0.089  -0.077  -0.069  -0.056
87    K        -0.221  -0.249  -0.282  -0.066  -0.104  -0.156  -0.329  -0.360  -0.393
88    I         0.225   0.243   0.241  -0.101  -0.065  -0.068  -0.077  -0.048  -0.044
89    T        -0.423  -0.448  -0.362  -0.682  -0.714  -0.598  -0.580  -0.601  -0.493
90    I         0.103   0.145   0.153  -0.193  -0.118  -0.163  -0.203  -0.140  -0.157
91    -        -0.444  -0.487  -0.407  -0.681  -0.766  -0.666  -0.585  -0.638  -0.540
92    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
93    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
94    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
95    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
96    E        -0.423  -0.394  -0.367  -0.612  -0.584  -0.515  -0.580  -0.556  -0.501
97    S        -0.746  -0.765  -0.748  -0.824  -0.849  -0.851  -0.705  -0.721  -0.680
98    S         1.342   1.350   1.206   1.319   1.331   1.169   1.429   1.442   1.156
99    D        -1.516  -1.521  -1.454  -1.367  -1.385  -1.303  -1.082  -1.084  -0.992
100   S        -1.192  -1.201  -1.135  -1.199  -1.206  -1.103  -0.956  -0.962  -0.869
101   N        -1.070  -1.082  -1.089  -0.878  -0.904  -0.904  -0.831  -0.843  -0.822
102   E        -1.516  -1.520  -1.462  -1.320  -1.323  -1.234  -1.082  -1.084  -0.998
103   S        -0.746  -0.742  -0.751  -0.800  -0.803  -0.785  -0.705  -0.706  -0.683
104   F        -1.516  -1.471  -1.454  -1.352  -1.267  -1.281  -1.082  -1.045  -0.992
105   S        -0.221  -0.274  -0.293  -0.343  -0.424  -0.453  -0.329  -0.392  -0.410
106   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
107   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
108   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
109   -        -0.439  -0.418  -0.376  -0.459  -0.422  -0.361  -0.594  -0.572  -0.508
110   -         1.204   1.222   1.128   1.331   1.358   1.204   1.192   1.223   1.004
111   -        -0.871  -0.889  -0.810  -0.920  -0.963  -0.860  -0.817  -0.835  -0.736
112   -        -0.871  -0.833  -0.808  -0.884  -0.818  -0.793  -0.817  -0.779  -0.734
113   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
114   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
115   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
116   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
117   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
118   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
119   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
120   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
121   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
122   L        -0.444  -0.470  -0.394  -0.623  -0.662  -0.555  -0.585  -0.617  -0.524
123   P         1.111   1.129   1.073   1.201   1.224   1.104   1.022   1.053   0.892
124   P        -0.962  -0.954  -0.857  -0.925  -0.918  -0.773  -0.906  -0.898  -0.782
125   P        -0.444  -0.455  -0.392  -0.431  -0.448  -0.347  -0.585  -0.600  -0.521
126   Q        -0.444  -0.432  -0.381  -0.504  -0.488  -0.419  -0.585  -0.571  -0.508
127   P        -0.962  -0.954  -0.857  -1.015  -1.012  -0.864  -0.906  -0.898  -0.782
128   K        -0.341  -0.332  -0.317  -0.522  -0.505  -0.476  -0.480  -0.467  -0.437
129   P        -0.341  -0.331  -0.334  -0.326  -0.320  -0.342  -0.480  -0.475  -0.459
130   K        -0.341  -0.311  -0.324  -0.373  -0.335  -0.345  -0.480  -0.453  -0.450
131   R        -0.341  -0.334  -0.323  -0.278  -0.276  -0.253  -0.480  -0.473  -0.447
132   V        -0.711  -0.725  -0.756  -0.761  -0.787  -0.839  -0.644  -0.660  -0.679
133   L        -0.850  -0.842  -0.801  -0.932  -0.925  -0.840  -0.808  -0.799  -0.731
134   K         0.225   0.206   0.232   0.029   0.003   0.035  -0.077  -0.104  -0.063
135   S        -0.746  -0.779  -0.750  -0.767  -0.794  -0.735  -0.705  -0.732  -0.678
136   T        -1.516  -1.520  -1.452  -1.306  -1.317  -1.214  -1.082  -1.085  -0.990
137   E        -1.192  -1.152  -1.140  -1.186  -1.130  -1.097  -0.956  -0.923  -0.873
138   M        -1.192  -1.194  -1.145  -1.257  -1.262  -1.186  -0.956  -0.957  -0.877
139   S        -1.516  -1.528  -1.450  -1.273  -1.298  -1.188  -1.082  -1.090  -0.989
140   I        -1.192  -1.177  -1.142  -1.126  -1.099  -1.048  -0.956  -0.943  -0.874
141   G        -0.221  -0.200  -0.264  -0.303  -0.282  -0.374  -0.329  -0.309  -0.372
142   G        -0.869  -0.863  -0.803  -0.997  -0.980  -0.889  -0.831  -0.824  -0.735
143   S        -0.300  -0.298  -0.306  -0.314  -0.315  -0.327  -0.454  -0.450  -0.433
144   G        -0.110  -0.135  -0.233  -0.108  -0.142  -0.290  -0.152  -0.185  -0.319
145   -        -0.444  -0.408  -0.374  -0.572  -0.515  -0.477  -0.585  -0.542  -0.499
146   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
147   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
148   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
149   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
150   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
151   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
152   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
153   E        -0.871  -0.876  -0.805  -0.901  -0.912  -0.821  -0.817  -0.822  -0.731
154   N        -0.850  -0.863  -0.805  -0.797  -0.810  -0.723  -0.808  -0.818  -0.734
155   V        -1.591  -1.584  -1.492  -1.382  -1.388  -1.237  -1.136  -1.130  -1.019
156   L         1.280   1.233   1.156   1.176   1.113   0.984   1.324   1.242   1.058
157   S        -0.850  -0.869  -0.813  -0.879  -0.901  -0.831  -0.808  -0.823  -0.742
158   V         0.558   0.569   0.391   0.480   0.496   0.211   0.504   0.521   0.223
159   H         0.770   0.781   0.885   0.758   0.776   0.927   0.340   0.358   0.494
160   P        -0.423  -0.396  -0.361  -0.508  -0.471  -0.407  -0.580  -0.549  -0.492
161   V        -0.423  -0.447  -0.382  -0.404  -0.413  -0.302  -0.580  -0.600  -0.516
162   L         0.671   0.687   0.458   0.895   0.916   0.565   0.676   0.700   0.330
163   D         1.342   1.277   1.200   1.380   1.297   1.186   1.429   1.318   1.145
164   D         1.342   1.277   1.200   1.405   1.326   1.233   1.429   1.318   1.145
165   N         1.342   1.277   1.200   1.502   1.423   1.310   1.429   1.318   1.145
166   S         1.342   1.277   1.200   1.281   1.196   1.089   1.429   1.318   1.145
167   C         1.342   1.277   1.200   1.689   1.611   1.517   1.429   1.318   1.145
168   L         0.995   1.011   0.981   0.848   0.869   0.824   0.801   0.828   0.701
169   F         1.342   1.277   1.200   1.567   1.485   1.374   1.429   1.318   1.145
170   H        -0.423  -0.447  -0.382  -0.262  -0.290  -0.203  -0.580  -0.600  -0.516
171   A         0.810   0.839   0.904   0.538   0.590   0.651   0.425   0.481   0.536
172   I         0.364   0.313   0.269   0.218   0.131   0.035   0.174   0.090   0.011
173   A         0.364   0.346   0.292   0.202   0.160   0.085   0.174   0.134   0.047
174   Y         0.671   0.588   0.436   0.953   0.838   0.601   0.676   0.550   0.294
175   G        -0.746  -0.753  -0.734  -0.639  -0.648  -0.609  -0.705  -0.708  -0.666
176   I        -0.746  -0.718  -0.734  -0.848  -0.798  -0.814  -0.705  -0.670  -0.666
177   F        -1.220  -1.226  -1.157  -0.883  -0.887  -0.789  -0.972  -0.976  -0.883
178   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
179   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
180   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
181   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
182   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
183   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
184   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
185   K        -0.110  -0.146  -0.225  -0.082  -0.140  -0.275  -0.152  -0.203  -0.308
186   Q        -1.220  -1.235  -1.157  -1.135  -1.169  -1.058  -0.972  -0.985  -0.884
187   D         0.260   0.238   0.232   0.100   0.052   0.044   0.012  -0.037  -0.046
188   S         0.558   0.462   0.361   0.536   0.402   0.235   0.504   0.354   0.175
189   V        -0.746  -0.747  -0.756  -0.747  -0.750  -0.786  -0.705  -0.704  -0.687
190   -        -0.341  -0.366  -0.335  -0.323  -0.374  -0.322  -0.480  -0.512  -0.462
191   R        -1.516  -1.521  -1.450  -1.260  -1.261  -1.142  -1.082  -1.085  -0.989
192   D        -0.545  -0.566  -0.658  -0.424  -0.457  -0.616  -0.454  -0.480  -0.572
193   L         2.046   2.056   2.178   1.890   1.904   2.085   2.308   2.327   2.538
194   R         2.046   2.056   2.178   2.183   2.197   2.382   2.308   2.327   2.538
195   E        -1.070  -1.055  -1.089  -0.890  -0.856  -0.921  -0.831  -0.817  -0.823
196   M        -0.423  -0.439  -0.356  -0.453  -0.462  -0.339  -0.580  -0.590  -0.488
197   V         0.671   0.697   0.458   0.816   0.849   0.532   0.676   0.714   0.331
198   S        -0.300  -0.265  -0.290  -0.466  -0.427  -0.445  -0.454  -0.419  -0.417
199   K        -0.746  -0.729  -0.743  -0.711  -0.669  -0.714  -0.705  -0.684  -0.675
200   E        -0.746  -0.752  -0.764  -0.627  -0.631  -0.634  -0.705  -0.712  -0.697
201   V         0.810   0.820   0.899   0.495   0.510   0.607   0.425   0.440   0.524
202   L        -0.545  -0.474  -0.656  -0.456  -0.360  -0.603  -0.454  -0.371  -0.569
203   N        -0.545  -0.456  -0.644  -0.477  -0.348  -0.621  -0.454  -0.350  -0.556
204   N         0.225   0.182   0.242   0.136   0.094   0.193  -0.077  -0.128  -0.048
205   P         0.671   0.697   0.458   0.943   0.976   0.649   0.676   0.714   0.331
206   V        -1.192  -1.201  -1.139  -1.119  -1.132  -1.029  -0.956  -0.961  -0.872
207   K        -0.869  -0.850  -0.802  -1.020  -0.987  -0.931  -0.831  -0.815  -0.735
208   F         1.342   1.367   1.212   1.597   1.628   1.443   1.429   1.471   1.169
209   N         0.225   0.185   0.240   0.012  -0.033   0.052  -0.077  -0.121  -0.048
210   D        -0.221  -0.244  -0.273  -0.239  -0.284  -0.323  -0.329  -0.365  -0.387
211   A         0.671   0.752   0.454   0.815   0.919   0.481   0.676   0.797   0.323
212   I         1.342   1.371   1.206   1.338   1.378   1.154   1.429   1.478   1.156
213   L         2.046   2.056   2.178   1.890   1.904   2.085   2.308   2.327   2.538
214   D         0.995   1.012   1.013   0.892   0.914   0.884   0.801   0.830   0.769
215   K        -0.221  -0.270  -0.280  -0.109  -0.188  -0.221  -0.329  -0.388  -0.395
216   P         0.671   0.697   0.458   0.907   0.939   0.587   0.676   0.714   0.331
217   N        -0.746  -0.774  -0.767  -0.592  -0.627  -0.631  -0.705  -0.729  -0.699
218   K        -1.516  -1.528  -1.450  -1.421  -1.453  -1.329  -1.082  -1.090  -0.989
219   D        -0.221  -0.247  -0.266  -0.281  -0.315  -0.357  -0.329  -0.358  -0.372
220   Y         2.046   2.056   2.178   2.200   2.213   2.400   2.308   2.327   2.538
221   A        -0.221  -0.177  -0.262  -0.051   0.009  -0.097  -0.329  -0.266  -0.365
222   Q        -0.423  -0.384  -0.372  -0.511  -0.465  -0.421  -0.580  -0.533  -0.507
223   W         1.342   1.277   1.200   1.718   1.637   1.542   1.429   1.318   1.145
224   I         1.342   1.277   1.200   1.377   1.302   1.219   1.429   1.318   1.145
225   L        -0.545  -0.507  -0.655  -0.446  -0.393  -0.589  -0.454  -0.410  -0.569
226   K         0.364   0.330   0.283   0.384   0.336   0.276   0.174   0.113   0.031
227   M        -1.070  -1.104  -1.103  -0.816  -0.874  -0.847  -0.831  -0.864  -0.835
228   E         0.040   0.054  -0.148   0.138   0.161  -0.162   0.048   0.067  -0.205
229   S         0.671   0.610   0.446   0.670   0.585   0.351   0.676   0.582   0.311
230   W         2.046   2.056   2.178   2.323   2.338   2.525   2.308   2.327   2.538
231   G         2.046   2.056   2.178   2.032   2.043   2.229   2.308   2.327   2.538
232   G         2.046   2.056   2.178   2.032   2.043   2.229   2.308   2.327   2.538
233   A         0.364   0.358   0.297   0.393   0.383   0.292   0.174   0.170   0.058
234   I         2.046   2.056   2.178   1.964   1.980   2.160   2.308   2.327   2.538
235   E         2.046   2.056   2.178   2.013   2.030   2.209   2.308   2.327   2.538
236   I         0.810   0.827   0.909   0.396   0.424   0.526   0.425   0.454   0.547
237   G        -0.221  -0.240  -0.293  -0.253  -0.309  -0.366  -0.329  -0.364  -0.410
238   I         2.046   2.056   2.178   1.964   1.980   2.160   2.308   2.327   2.538
239   I         1.342   1.367   1.212   1.255   1.288   1.074   1.429   1.471   1.169
240   S         0.810   0.837   0.905   0.475   0.517   0.604   0.425   0.477   0.538
241   D        -0.221  -0.215  -0.269  -0.311  -0.299  -0.408  -0.329  -0.320  -0.380
242   A        -1.192  -1.209  -1.153  -0.757  -0.792  -0.708  -0.956  -0.968  -0.882
243   L         0.225   0.181   0.237   0.130   0.077   0.159  -0.077  -0.128  -0.054
244   A        -0.869  -0.851  -0.801  -0.844  -0.820  -0.731  -0.831  -0.816  -0.734
245   V        -0.221  -0.233  -0.276  -0.276  -0.314  -0.377  -0.329  -0.353  -0.390
246   A        -0.423  -0.422  -0.381  -0.456  -0.469  -0.398  -0.580  -0.580  -0.516
247   I         2.046   2.056   2.178   1.964   1.980   2.160   2.308   2.327   2.538
248   Y        -1.070  -1.079  -1.118  -0.754  -0.777  -0.857  -0.831  -0.841  -0.849
249   V         0.024   0.050   0.131  -0.213  -0.191  -0.057  -0.329  -0.294  -0.193
250   V        -0.423  -0.427  -0.369  -0.713  -0.724  -0.630  -0.580  -0.585  -0.504
251   D         2.046   2.056   2.178   2.008   2.023   2.205   2.308   2.327   2.538
252   I         0.225   0.248   0.242  -0.031   0.013  -0.010  -0.077  -0.039  -0.044
253   D        -0.423  -0.422  -0.381  -0.648  -0.644  -0.603  -0.580  -0.580  -0.516
254   A        -0.423  -0.402  -0.360  -0.616  -0.593  -0.541  -0.580  -0.558  -0.492
255   V        -0.221  -0.217  -0.284  -0.276  -0.295  -0.389  -0.329  -0.334  -0.401
256   K        -0.300  -0.259  -0.305  -0.277  -0.214  -0.262  -0.454  -0.411  -0.432
257   I        -0.423  -0.435  -0.376  -0.520  -0.553  -0.477  -0.580  -0.596  -0.510
258   E        -0.423  -0.390  -0.368  -0.639  -0.577  -0.558  -0.580  -0.537  -0.500
259   K        -0.300  -0.313  -0.320  -0.282  -0.292  -0.285  -0.454  -0.465  -0.448
260   F         1.342   1.326   1.200   1.592   1.577   1.419   1.429   1.403   1.144
261   N         0.364   0.347   0.311   0.397   0.393   0.305   0.174   0.164   0.085
262   E         0.103   0.127   0.169  -0.014   0.027   0.078  -0.203  -0.168  -0.131
263   D         0.156   0.117   0.188  -0.017  -0.059   0.033  -0.147  -0.195  -0.112
264   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
265   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
266   K        -0.746  -0.727  -0.752  -0.731  -0.717  -0.732  -0.705  -0.692  -0.684
267   F        -0.869  -0.863  -0.814  -0.729  -0.726  -0.639  -0.831  -0.823  -0.745
268   D        -0.545  -0.572  -0.681  -0.430  -0.481  -0.662  -0.454  -0.488  -0.598
269   N        -1.192  -1.223  -1.139  -1.110  -1.153  -1.033  -0.956  -0.979  -0.872
270   Y         0.364   0.339   0.290   0.552   0.504   0.446   0.174   0.121   0.044
271   I         0.040   0.019  -0.158   0.176   0.149  -0.094   0.048   0.020  -0.219
272   L         0.364   0.323   0.284   0.227   0.158   0.084   0.174   0.108   0.032
273   I         0.364   0.403   0.310   0.192   0.266   0.093   0.174   0.242   0.083
274   L        -0.746  -0.732  -0.745  -0.884  -0.880  -0.911  -0.705  -0.694  -0.678
275   F         0.995   1.012   1.013   1.112   1.136   1.120   0.801   0.830   0.769
276   N         0.225   0.252   0.236  -0.026   0.013  -0.012  -0.077  -0.042  -0.050
277   G         2.046   2.056   2.178   2.032   2.043   2.229   2.308   2.327   2.538
278   I         0.995   1.013   0.996   0.831   0.859   0.794   0.801   0.833   0.732
279   H         2.046   2.056   2.178   2.269   2.285   2.470   2.308   2.327   2.538
280   Y         2.046   2.056   2.178   2.200   2.213   2.400   2.308   2.327   2.538
281   D         2.046   2.056   2.178   2.008   2.023   2.205   2.308   2.327   2.538
282   S        -1.516  -1.511  -1.450  -1.519  -1.508  -1.422  -1.082  -1.077  -0.989
283   L        -0.300  -0.348  -0.305  -0.518  -0.582  -0.510  -0.454  -0.500  -0.433
284   T        -0.221  -0.182  -0.274  -0.227  -0.173  -0.327  -0.329  -0.280  -0.383
285   M        -0.545  -0.525  -0.633  -0.443  -0.415  -0.554  -0.454  -0.433  -0.544
286   -        -0.341  -0.330  -0.333  -0.321  -0.304  -0.313  -0.480  -0.458  -0.454
287   -        -1.302  -1.290  -1.201  -1.115  -1.080  -0.965  -1.040  -1.029  -0.920
288   -        -0.444  -0.428  -0.388  -0.522  -0.502  -0.452  -0.585  -0.568  -0.517
289   -         1.111   1.129   1.065   0.872   0.898   0.756   1.022   1.053   0.877
290   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
291   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
292   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
293   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
294   -        -0.871  -0.851  -0.809  -0.567  -0.535  -0.474  -0.817  -0.798  -0.735
295   -        -0.711  -0.711  -0.720  -0.543  -0.544  -0.549  -0.644  -0.647  -0.640
296   -        -0.850  -0.861  -0.799  -0.863  -0.875  -0.780  -0.808  -0.815  -0.728
297   N        -1.192  -1.202  -1.150  -1.104  -1.120  -1.046  -0.956  -0.962  -0.881
298   E        -0.746  -0.707  -0.735  -0.732  -0.672  -0.713  -0.705  -0.658  -0.663
299   F         0.040   0.074  -0.162   0.269   0.314   0.019   0.048   0.094  -0.224
300   K        -0.221  -0.182  -0.272  -0.214  -0.158  -0.277  -0.329  -0.280  -0.379
301   T         0.040   0.092  -0.157   0.284   0.348   0.012   0.048   0.117  -0.217
302   V         0.040   0.013  -0.157   0.177   0.128  -0.127   0.048   0.009  -0.217
303   F         0.810   0.817   0.900   0.852   0.865   0.982   0.425   0.435   0.528
304   N        -0.423  -0.404  -0.366  -0.598  -0.575  -0.503  -0.580  -0.560  -0.499
305   K        -1.192  -1.194  -1.136  -1.175  -1.174  -1.092  -0.956  -0.956  -0.870
306   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
307   N        -0.439  -0.447  -0.369  -0.626  -0.643  -0.525  -0.594  -0.602  -0.500
308   Q        -0.221  -0.182  -0.274  -0.217  -0.160  -0.279  -0.329  -0.280  -0.383
309   P        -1.192  -1.202  -1.150  -1.127  -1.144  -1.083  -0.956  -0.962  -0.881
310   E        -0.746  -0.722  -0.746  -0.682  -0.643  -0.681  -0.705  -0.676  -0.678
311   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
312   S        -0.871  -0.883  -0.832  -0.874  -0.896  -0.817  -0.817  -0.829  -0.757
313   D        -0.276  -0.306  -0.320  -0.307  -0.357  -0.399  -0.370  -0.411  -0.431
314   D        -0.871  -0.883  -0.804  -0.890  -0.909  -0.796  -0.817  -0.830  -0.730
315   V         0.364   0.401   0.302   0.254   0.312   0.121   0.174   0.231   0.063
316   L         1.342   1.326   1.200   1.271   1.251   1.084   1.429   1.403   1.144
317   T        -1.070  -1.067  -1.071  -0.861  -0.864  -0.859  -0.831  -0.829  -0.806
318   A        -0.423  -0.405  -0.366  -0.508  -0.479  -0.427  -0.580  -0.556  -0.501
319   A        -0.869  -0.873  -0.807  -1.021  -1.025  -0.928  -0.831  -0.832  -0.739
320   L        -0.746  -0.779  -0.740  -0.679  -0.717  -0.683  -0.705  -0.734  -0.672
321   Q        -0.423  -0.420  -0.374  -0.517  -0.506  -0.439  -0.580  -0.575  -0.509
322   L         1.342   1.369   1.205   1.255   1.290   1.062   1.429   1.474   1.154
323   A        -0.221  -0.191  -0.261  -0.025   0.014  -0.058  -0.329  -0.282  -0.363
324   S        -0.746  -0.776  -0.746  -0.767  -0.813  -0.757  -0.705  -0.735  -0.678
325   N        -1.192  -1.202  -1.146  -1.145  -1.145  -1.052  -0.956  -0.963  -0.878
326   L         1.342   1.369   1.205   1.304   1.337   1.153   1.429   1.474   1.154
327   K         0.225   0.231   0.239   0.161   0.174   0.209  -0.077  -0.070  -0.050
328   Q        -1.192  -1.185  -1.131  -1.061  -1.036  -0.959  -0.956  -0.948  -0.866
329   T        -1.192  -1.166  -1.143  -0.994  -0.937  -0.926  -0.956  -0.933  -0.876
330   G        -0.300  -0.247  -0.316  -0.215  -0.139  -0.217  -0.454  -0.400  -0.444
331   Y         1.342   1.369   1.205   1.572   1.607   1.384   1.429   1.474   1.154
332   S        -0.300  -0.259  -0.305  -0.364  -0.299  -0.357  -0.454  -0.411  -0.432
333   F         0.810   0.827   0.909   0.682   0.707   0.821   0.425   0.454   0.547
334   N         0.810   0.792   0.888   0.631   0.591   0.713   0.425   0.381   0.501
335   T         2.046   2.056   2.178   2.074   2.086   2.271   2.308   2.327   2.538
336   H        -0.300  -0.286  -0.304  -0.245  -0.234  -0.207  -0.454  -0.439  -0.432
337   K        -0.869  -0.880  -0.817  -0.979  -1.000  -0.892  -0.831  -0.838  -0.747
338   A         0.364   0.392   0.294   0.467   0.511   0.341   0.174   0.216   0.053
339   Q        -1.192  -1.209  -1.153  -1.092  -1.128  -1.036  -0.956  -0.968  -0.882
340   I         0.995   1.032   0.993   0.831   0.891   0.789   0.801   0.870   0.726
341   K         0.225   0.254   0.239   0.095   0.141   0.116  -0.077  -0.037  -0.048
342   C         2.046   2.056   2.178   2.292   2.309   2.493   2.308   2.327   2.538
343   N        -0.221  -0.256  -0.275  -0.216  -0.248  -0.307  -0.329  -0.360  -0.381
344   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
345   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
346   T        -0.746  -0.789  -0.764  -0.773  -0.839  -0.809  -0.705  -0.744  -0.694
347   C         2.046   2.056   2.178   2.292   2.309   2.493   2.308   2.327   2.538
348   Q        -0.221  -0.174  -0.260  -0.136  -0.069  -0.179  -0.329  -0.262  -0.362
349   M        -1.192  -1.200  -1.142  -1.032  -1.025  -0.928  -0.956  -0.961  -0.875
350   T        -0.746  -0.733  -0.742  -0.766  -0.759  -0.774  -0.705  -0.696  -0.675
351   F         0.225   0.181   0.237   0.033  -0.021   0.069  -0.077  -0.128  -0.054
352   V         0.040  -0.006  -0.164   0.204   0.141  -0.096   0.048  -0.014  -0.226
353   G         2.046   2.056   2.178   2.032   2.043   2.229   2.308   2.327   2.538
354   E         1.342   1.277   1.200   1.394   1.313   1.207   1.429   1.318   1.145
355   R         0.024   0.050   0.131  -0.042  -0.011   0.114  -0.329  -0.294  -0.193
356   E         0.024   0.012   0.114  -0.270  -0.293  -0.147  -0.329  -0.345  -0.217
357   V         0.810   0.827   0.909   0.600   0.622   0.732   0.425   0.454   0.547
358   A        -0.300  -0.310  -0.308  -0.484  -0.493  -0.489  -0.454  -0.461  -0.436
359   R        -0.221  -0.233  -0.268  -0.188  -0.198  -0.253  -0.329  -0.340  -0.374
360   H         2.046   2.056   2.178   2.269   2.285   2.470   2.308   2.327   2.538
361   A         1.342   1.277   1.200   1.455   1.364   1.260   1.429   1.318   1.145
362   E        -0.545  -0.599  -0.682  -0.402  -0.478  -0.624  -0.454  -0.518  -0.599
363   S        -0.423  -0.426  -0.374  -0.653  -0.650  -0.581  -0.580  -0.580  -0.508
364   T         1.342   1.350   1.206   1.431   1.440   1.232   1.429   1.442   1.156
365   G         2.046   2.056   2.178   2.032   2.043   2.229   2.308   2.327   2.538
366   H         2.046   2.056   2.178   2.269   2.285   2.470   2.308   2.327   2.538
367   V        -0.869  -0.866  -0.806  -0.871  -0.871  -0.781  -0.831  -0.828  -0.738
368   D        -0.300  -0.348  -0.325  -0.277  -0.327  -0.268  -0.454  -0.501  -0.453
369   F         2.046   2.056   2.178   2.194   2.211   2.393   2.308   2.327   2.538
370   G         1.342   1.369   1.205   1.429   1.460   1.264   1.429   1.474   1.154
371   Q         0.810   0.827   0.909   0.629   0.656   0.769   0.425   0.454   0.547
372   N        -0.746  -0.784  -0.753  -0.627  -0.664  -0.605  -0.705  -0.741  -0.686
373   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
374   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
375   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P43558
Output conservation file - output/P43558
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
