1     M         0.893   0.901   0.960   1.035   1.046   1.125   0.946   0.956   1.036
2     S        -0.852  -0.869  -0.872  -0.842  -0.870  -0.948  -1.022  -1.050  -1.004
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.639  -1.621  -1.404  -1.716  -1.663  -1.365  -1.636  -1.611  -1.314
12    E        -1.576  -1.558  -1.393  -1.585  -1.533  -1.286  -1.584  -1.557  -1.304
13    F         0.144   0.166  -0.115   0.452   0.484   0.043   0.103   0.136  -0.338
14    K        -0.561  -0.654  -0.836  -0.411  -0.531  -0.783  -0.600  -0.726  -0.953
15    V         0.144   0.152  -0.117   0.105   0.120  -0.291   0.103   0.115  -0.341
16    K         0.144   0.152  -0.117   0.227   0.244  -0.132   0.103   0.115  -0.341
17    T        -0.561  -0.471  -0.822  -0.728  -0.618  -1.030  -0.600  -0.478  -0.934
18    G         0.893   0.901   0.960   0.813   0.820   0.924   0.946   0.956   1.036
19    L         0.893   0.901   0.960   0.895   0.912   0.998   0.946   0.956   1.036
20    A         0.893   0.901   0.960   0.579   0.580   0.712   0.946   0.956   1.036
21    Q         0.893   0.901   0.960   1.099   1.113   1.183   0.946   0.956   1.036
22    M         0.893   0.901   0.960   1.035   1.046   1.125   0.946   0.956   1.036
23    L         0.893   0.901   0.960   0.895   0.912   0.998   0.946   0.956   1.036
24    K         0.893   0.901   0.960   0.879   0.894   0.984   0.946   0.956   1.036
25    G         0.893   0.901   0.960   0.813   0.820   0.924   0.946   0.956   1.036
26    G         0.893   0.901   0.960   0.813   0.820   0.924   0.946   0.956   1.036
27    V         0.893   0.901   0.960   0.792   0.804   0.905   0.946   0.956   1.036
28    I         0.893   0.901   0.960   0.895   0.909   0.998   0.946   0.956   1.036
29    M         0.893   0.901   0.960   1.035   1.046   1.125   0.946   0.956   1.036
30    D         0.893   0.901   0.960   0.981   0.993   1.076   0.946   0.956   1.036
31    V         0.893   0.901   0.960   0.792   0.804   0.905   0.946   0.956   1.036
32    V         0.144   0.025  -0.126   0.131  -0.024  -0.242   0.103  -0.083  -0.358
33    T        -0.354  -0.343  -0.218  -0.348  -0.328  -0.148  -0.740  -0.720  -0.524
34    P        -0.354  -0.350  -0.220  -0.760  -0.754  -0.500  -0.740  -0.733  -0.527
35    E        -0.561  -0.664  -0.834  -0.568  -0.741  -1.054  -0.600  -0.739  -0.950
36    Q         0.144   0.025  -0.126   0.402   0.234  -0.073   0.103  -0.083  -0.358
37    A         0.893   0.901   0.960   0.579   0.580   0.712   0.946   0.956   1.036
38    I        -1.077  -1.070  -0.905  -1.253  -1.229  -0.980  -1.303  -1.290  -1.043
39    I         0.893   0.901   0.960   0.895   0.909   0.998   0.946   0.956   1.036
40    A         0.893   0.901   0.960   0.579   0.580   0.712   0.946   0.956   1.036
41    E         0.144   0.152  -0.117   0.186   0.200  -0.166   0.103   0.115  -0.341
42    R        -1.576  -1.528  -1.390  -1.939  -1.876  -1.603  -1.584  -1.535  -1.302
43    A         0.893   0.901   0.960   0.579   0.580   0.712   0.946   0.956   1.036
44    G         0.893   0.901   0.960   0.813   0.820   0.924   0.946   0.956   1.036
45    A         0.893   0.901   0.960   0.579   0.580   0.712   0.946   0.956   1.036
46    C         0.144   0.152  -0.117   0.458   0.471  -0.019   0.103   0.115  -0.341
47    A         0.893   0.901   0.960   0.579   0.580   0.712   0.946   0.956   1.036
48    V         0.893   0.901   0.960   0.792   0.804   0.905   0.946   0.956   1.036
49    M         0.893   0.901   0.960   1.035   1.046   1.125   0.946   0.956   1.036
50    A         0.893   0.901   0.960   0.579   0.580   0.712   0.946   0.956   1.036
51    L         0.893   0.901   0.960   0.895   0.912   0.998   0.946   0.956   1.036
52    E         0.893   0.901   0.960   0.838   0.850   0.947   0.946   0.956   1.036
53    R        -0.561  -0.541  -0.825  -0.301  -0.274  -0.723  -0.600  -0.571  -0.938
54    I         0.144   0.166  -0.115   0.191   0.226  -0.242   0.103   0.136  -0.338
55    P         0.893   0.901   0.960   1.077   1.089   1.163   0.946   0.956   1.036
56    A         0.144   0.025  -0.126  -0.090  -0.254  -0.437   0.103  -0.083  -0.358
57    D         0.144   0.155  -0.115   0.284   0.302  -0.150   0.103   0.119  -0.338
58    M        -0.354  -0.360  -0.222  -0.502  -0.522  -0.310  -0.740  -0.753  -0.530
59    R         0.893   0.901   0.960   1.026   1.033   1.116   0.946   0.956   1.036
60    K        -0.354  -0.328  -0.214  -0.894  -0.858  -0.631  -0.740  -0.694  -0.516
61    S        -1.214  -1.290  -1.360  -1.016  -1.157  -1.317  -1.162  -1.248  -1.271
62    G         0.144   0.155  -0.115   0.167   0.179  -0.169   0.103   0.119  -0.338
63    Q        -0.941  -0.919  -0.884  -1.032  -1.012  -0.941  -1.162  -1.129  -1.018
64    V         0.893   0.901   0.960   0.792   0.804   0.905   0.946   0.956   1.036
65    C        -0.354  -0.360  -0.222  -0.581  -0.635  -0.418  -0.740  -0.753  -0.530
66    R         0.893   0.901   0.960   1.026   1.033   1.116   0.946   0.956   1.036
67    M         0.893   0.901   0.960   1.035   1.046   1.125   0.946   0.956   1.036
68    S         0.893   0.901   0.960   1.006   1.023   1.098   0.946   0.956   1.036
69    D         0.144   0.025  -0.126   0.333   0.183  -0.050   0.103  -0.083  -0.358
70    P         0.893   0.901   0.960   1.077   1.089   1.163   0.946   0.956   1.036
71    R        -1.439  -1.405  -1.376  -1.511  -1.464  -1.438  -1.443  -1.412  -1.289
72    M         0.893   0.901   0.960   1.035   1.046   1.125   0.946   0.956   1.036
73    I         0.893   0.901   0.960   0.895   0.909   0.998   0.946   0.956   1.036
74    K         0.893   0.901   0.960   0.879   0.894   0.984   0.946   0.956   1.036
75    E         0.144   0.155  -0.115   0.166   0.183  -0.212   0.103   0.119  -0.338
76    I         0.893   0.901   0.960   0.895   0.909   0.998   0.946   0.956   1.036
77    M        -0.199  -0.249  -0.201  -0.112  -0.194  -0.148  -0.459  -0.549  -0.492
78    E        -0.852  -0.801  -0.866  -1.206  -1.131  -1.129  -1.022  -0.945  -0.995
79    A        -0.852  -0.817  -0.865  -1.136  -1.091  -1.072  -1.022  -0.969  -0.993
80    V         0.893   0.901   0.960   0.792   0.804   0.905   0.946   0.956   1.036
81    S        -0.561  -0.664  -0.834  -0.331  -0.465  -0.775  -0.600  -0.739  -0.950
82    I         0.893   0.901   0.960   0.895   0.909   0.998   0.946   0.956   1.036
83    P         0.893   0.901   0.960   1.077   1.089   1.163   0.946   0.956   1.036
84    V         0.893   0.901   0.960   0.792   0.804   0.905   0.946   0.956   1.036
85    M         0.893   0.901   0.960   1.035   1.046   1.125   0.946   0.956   1.036
86    A         0.893   0.901   0.960   0.579   0.580   0.712   0.946   0.956   1.036
87    K         0.893   0.901   0.960   0.879   0.894   0.984   0.946   0.956   1.036
88    V        -0.941  -1.005  -0.882  -1.069  -1.174  -1.021  -1.162  -1.220  -1.016
89    R         0.893   0.901   0.960   1.026   1.033   1.116   0.946   0.956   1.036
90    I         0.893   0.901   0.960   0.895   0.909   0.998   0.946   0.956   1.036
91    G         0.893   0.901   0.960   0.813   0.820   0.924   0.946   0.956   1.036
92    H         0.893   0.901   0.960   1.165   1.177   1.242   0.946   0.956   1.036
93    F         0.144   0.025  -0.126   0.412   0.240  -0.077   0.103  -0.083  -0.358
94    V        -0.199  -0.254  -0.205  -0.361  -0.447  -0.363  -0.459  -0.557  -0.500
95    E         0.893   0.901   0.960   0.838   0.850   0.947   0.946   0.956   1.036
96    A        -0.561  -0.664  -0.834  -0.702  -0.834  -0.991  -0.600  -0.739  -0.950
97    Q         0.144   0.025  -0.126   0.432   0.274   0.001   0.103  -0.083  -0.358
98    I         0.893   0.901   0.960   0.895   0.909   0.998   0.946   0.956   1.036
99    L         0.144   0.152  -0.117   0.208   0.228  -0.204   0.103   0.115  -0.341
100   E         0.144   0.165  -0.116   0.186   0.216  -0.165   0.103   0.134  -0.340
101   E        -1.439  -1.478  -1.376  -1.723  -1.752  -1.510  -1.443  -1.471  -1.289
102   L        -0.199  -0.184  -0.186  -0.322  -0.288  -0.335  -0.459  -0.433  -0.465
103   Q        -0.852  -0.760  -0.864  -0.997  -0.867  -0.976  -1.022  -0.901  -0.992
104   V         0.144   0.165  -0.116   0.105   0.136  -0.289   0.103   0.134  -0.340
105   D         0.893   0.901   0.960   0.981   0.993   1.076   0.946   0.956   1.036
106   Y         0.893   0.901   0.960   1.182   1.193   1.258   0.946   0.956   1.036
107   I         0.893   0.901   0.960   0.895   0.909   0.998   0.946   0.956   1.036
108   D         0.893   0.901   0.960   0.981   0.993   1.076   0.946   0.956   1.036
109   E         0.893   0.901   0.960   0.838   0.850   0.947   0.946   0.956   1.036
110   S         0.893   0.901   0.960   1.006   1.023   1.098   0.946   0.956   1.036
111   E         0.893   0.901   0.960   0.838   0.850   0.947   0.946   0.956   1.036
112   V         0.893   0.901   0.960   0.792   0.804   0.905   0.946   0.956   1.036
113   L         0.893   0.901   0.960   0.895   0.912   0.998   0.946   0.956   1.036
114   T         0.893   0.901   0.960   1.045   1.056   1.134   0.946   0.956   1.036
115   P         0.893   0.901   0.960   1.077   1.089   1.163   0.946   0.956   1.036
116   A         0.893   0.901   0.960   0.579   0.580   0.712   0.946   0.956   1.036
117   D         0.893   0.901   0.960   0.981   0.993   1.076   0.946   0.956   1.036
118   W        -1.937  -1.904  -1.770  -1.596  -1.553  -1.388  -1.724  -1.686  -1.460
119   T        -2.299  -2.261  -2.080  -2.101  -2.023  -1.824  -1.865  -1.824  -1.565
120   H        -1.439  -1.393  -1.370  -1.092  -1.016  -1.034  -1.443  -1.383  -1.282
121   H         0.893   0.901   0.960   1.165   1.177   1.242   0.946   0.956   1.036
122   I         0.144   0.025  -0.126   0.191   0.022  -0.264   0.103  -0.083  -0.358
123   E        -1.937  -1.967  -1.768  -1.845  -1.852  -1.548  -1.724  -1.738  -1.458
124   K         0.893   0.901   0.960   0.879   0.894   0.984   0.946   0.956   1.036
125   H        -2.299  -2.243  -2.081  -1.862  -1.788  -1.560  -1.865  -1.810  -1.566
126   N        -1.576  -1.531  -1.390  -1.495  -1.430  -1.203  -1.584  -1.539  -1.302
127   F         0.893   0.901   0.960   1.116   1.128   1.198   0.946   0.956   1.036
128   K        -0.561  -0.529  -0.821  -0.403  -0.355  -0.747  -0.600  -0.554  -0.933
129   V         0.144   0.025  -0.126   0.052  -0.133  -0.442   0.103  -0.083  -0.358
130   P         0.893   0.901   0.960   1.077   1.089   1.163   0.946   0.956   1.036
131   F         0.893   0.901   0.960   1.116   1.128   1.198   0.946   0.956   1.036
132   V         0.893   0.901   0.960   0.792   0.804   0.905   0.946   0.956   1.036
133   C         0.893   0.901   0.960   1.163   1.173   1.240   0.946   0.956   1.036
134   G         0.893   0.901   0.960   0.813   0.820   0.924   0.946   0.956   1.036
135   A        -0.561  -0.654  -0.836  -0.702  -0.821  -0.993  -0.600  -0.726  -0.953
136   K        -0.354  -0.329  -0.217  -0.519  -0.467  -0.312  -0.740  -0.695  -0.521
137   D        -0.199  -0.144  -0.178  -0.063   0.034  -0.088  -0.459  -0.363  -0.450
138   L         0.893   0.901   0.960   0.895   0.912   0.998   0.946   0.956   1.036
139   G         0.893   0.901   0.960   0.813   0.820   0.924   0.946   0.956   1.036
140   E         0.893   0.901   0.960   0.838   0.850   0.947   0.946   0.956   1.036
141   A         0.893   0.901   0.960   0.579   0.580   0.712   0.946   0.956   1.036
142   L         0.893   0.901   0.960   0.895   0.912   0.998   0.946   0.956   1.036
143   R         0.893   0.901   0.960   1.026   1.033   1.116   0.946   0.956   1.036
144   R         0.893   0.901   0.960   1.026   1.033   1.116   0.946   0.956   1.036
145   I         0.144   0.192  -0.112   0.191   0.260  -0.237   0.103   0.174  -0.333
146   N        -1.937  -1.964  -1.769  -1.679  -1.719  -1.465  -1.724  -1.735  -1.460
147   E         0.893   0.901   0.960   0.838   0.850   0.947   0.946   0.956   1.036
148   G         0.893   0.901   0.960   0.813   0.820   0.924   0.946   0.956   1.036
149   A         0.893   0.901   0.960   0.579   0.580   0.712   0.946   0.956   1.036
150   A         0.893   0.901   0.960   0.579   0.580   0.712   0.946   0.956   1.036
151   M         0.144   0.152  -0.117   0.384   0.397   0.002   0.103   0.115  -0.341
152   I         0.144   0.192  -0.112   0.208   0.276  -0.196   0.103   0.174  -0.333
153   R         0.893   0.901   0.960   1.026   1.033   1.116   0.946   0.956   1.036
154   T         0.144   0.155  -0.115   0.402   0.418   0.031   0.103   0.119  -0.338
155   K         0.893   0.901   0.960   0.879   0.894   0.984   0.946   0.956   1.036
156   G         0.893   0.901   0.960   0.813   0.820   0.924   0.946   0.956   1.036
157   E         0.893   0.901   0.960   0.838   0.850   0.947   0.946   0.956   1.036
158   A         0.893   0.901   0.960   0.579   0.580   0.712   0.946   0.956   1.036
159   G         0.893   0.901   0.960   0.813   0.820   0.924   0.946   0.956   1.036
160   T         0.893   0.901   0.960   1.045   1.056   1.134   0.946   0.956   1.036
161   G         0.893   0.901   0.960   0.813   0.820   0.924   0.946   0.956   1.036
162   D         0.893   0.901   0.960   0.981   0.993   1.076   0.946   0.956   1.036
163   V         0.144   0.192  -0.112   0.105   0.171  -0.283   0.103   0.174  -0.333
164   S        -0.852  -0.885  -0.881  -0.854  -0.923  -0.920  -1.022  -1.071  -1.014
165   E         0.144   0.155  -0.115   0.170   0.188  -0.202   0.103   0.119  -0.338
166   A         0.893   0.901   0.960   0.579   0.580   0.712   0.946   0.956   1.036
167   V         0.893   0.901   0.960   0.792   0.804   0.905   0.946   0.956   1.036
168   K        -1.214  -1.161  -1.338  -1.056  -0.974  -1.232  -1.162  -1.095  -1.248
169   H         0.893   0.901   0.960   1.165   1.177   1.242   0.946   0.956   1.036
170   I        -0.561  -0.540  -0.827  -0.409  -0.375  -0.785  -0.600  -0.569  -0.942
171   T        -1.214  -1.102  -1.339  -0.905  -0.752  -1.113  -1.162  -1.026  -1.249
172   K        -1.439  -1.371  -1.365  -1.338  -1.213  -1.225  -1.443  -1.360  -1.277
173   I        -0.561  -0.654  -0.836  -0.459  -0.599  -0.902  -0.600  -0.726  -0.953
174   K        -0.852  -0.934  -0.880  -0.808  -0.898  -0.799  -1.022  -1.112  -1.012
175   A        -1.937  -1.904  -1.763  -2.081  -2.049  -1.790  -1.724  -1.688  -1.455
176   E        -0.561  -0.514  -0.820  -0.464  -0.400  -0.817  -0.600  -0.535  -0.932
177   I         0.144   0.166  -0.115   0.208   0.243  -0.200   0.103   0.136  -0.338
178   Q        -2.661  -2.635  -2.358  -2.459  -2.483  -2.037  -2.005  -1.978  -1.650
179   Q        -1.937  -1.905  -1.765  -1.748  -1.695  -1.485  -1.724  -1.688  -1.456
180   Y        -1.439  -1.398  -1.371  -1.592  -1.554  -1.440  -1.443  -1.386  -1.283
181   K        -1.801  -1.757  -1.748  -1.611  -1.535  -1.525  -1.584  -1.533  -1.442
182   E        -2.299  -2.294  -2.084  -2.179  -2.208  -1.905  -1.865  -1.853  -1.568
183   N        -1.937  -1.934  -1.773  -1.852  -1.893  -1.621  -1.724  -1.714  -1.462
184   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
185   K        -0.842  -0.924  -0.884  -1.061  -1.245  -1.220  -0.982  -1.096  -1.015
186   T        -0.852  -0.801  -0.866  -0.756  -0.665  -0.787  -1.022  -0.945  -0.995
187   E        -1.214  -1.281  -1.351  -1.129  -1.240  -1.334  -1.162  -1.238  -1.261
188   S        -2.299  -2.279  -2.085  -2.216  -2.197  -1.960  -1.865  -1.842  -1.569
189   D        -0.199  -0.144  -0.178  -0.343  -0.249  -0.320  -0.459  -0.363  -0.450
190   F        -1.439  -1.379  -1.373  -1.415  -1.315  -1.341  -1.443  -1.367  -1.285
191   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
192   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
193   A        -1.439  -1.418  -1.370  -1.642  -1.617  -1.507  -1.443  -1.413  -1.282
194   A        -1.937  -1.962  -1.772  -2.042  -2.056  -1.762  -1.724  -1.733  -1.462
195   K        -1.801  -1.808  -1.756  -1.401  -1.410  -1.428  -1.584  -1.588  -1.449
196   A         0.893   0.901   0.960   0.579   0.580   0.712   0.946   0.956   1.036
197   T        -1.576  -1.528  -1.391  -1.650  -1.576  -1.344  -1.584  -1.535  -1.303
198   E         0.144   0.165  -0.116   0.170   0.201  -0.204   0.103   0.134  -0.340
199   L        -0.354  -0.322  -0.212  -0.619  -0.550  -0.386  -0.740  -0.682  -0.512
200   R        -0.941  -0.917  -0.877  -1.159  -1.137  -1.098  -1.162  -1.128  -1.010
201   V        -0.354  -0.360  -0.222  -0.906  -0.942  -0.688  -0.740  -0.753  -0.530
202   P        -0.852  -0.934  -0.874  -0.710  -0.820  -0.774  -1.022  -1.113  -1.006
203   V        -2.299  -2.261  -2.080  -2.080  -2.020  -1.742  -1.865  -1.824  -1.565
204   D        -0.941  -0.903  -0.877  -1.099  -1.047  -0.981  -1.162  -1.114  -1.010
205   L         0.144   0.192  -0.112   0.233   0.302  -0.135   0.103   0.174  -0.333
206   L         0.144   0.166  -0.115   0.191   0.229  -0.242   0.103   0.136  -0.338
207   K        -0.561  -0.514  -0.820  -0.441  -0.373  -0.820  -0.600  -0.535  -0.932
208   T        -2.299  -2.294  -2.084  -2.059  -2.058  -1.732  -1.865  -1.853  -1.568
209   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
210   T        -1.439  -1.392  -1.367  -1.367  -1.289  -1.251  -1.443  -1.388  -1.279
211   L        -0.852  -0.805  -0.864  -1.241  -1.166  -1.205  -1.022  -0.947  -0.991
212   S        -2.299  -2.225  -2.079  -2.059  -1.961  -1.731  -1.865  -1.796  -1.565
213   E        -1.439  -1.421  -1.372  -1.495  -1.470  -1.354  -1.443  -1.426  -1.285
214   G         0.144   0.155  -0.115   0.123   0.136  -0.276   0.103   0.119  -0.338
215   K        -0.354  -0.360  -0.222  -0.549  -0.555  -0.331  -0.740  -0.753  -0.530
216   L         0.144   0.192  -0.112   0.245   0.313  -0.106   0.103   0.174  -0.333
217   P         0.893   0.901   0.960   1.077   1.089   1.163   0.946   0.956   1.036
218   V         0.893   0.901   0.960   0.792   0.804   0.905   0.946   0.956   1.036
219   V         0.893   0.901   0.960   0.792   0.804   0.905   0.946   0.956   1.036
220   N         0.144   0.155  -0.115   0.448   0.464   0.001   0.103   0.119  -0.338
221   F         0.893   0.901   0.960   1.116   1.128   1.198   0.946   0.956   1.036
222   A         0.144   0.155  -0.115  -0.061  -0.054  -0.350   0.103   0.119  -0.338
223   A         0.893   0.901   0.960   0.579   0.580   0.712   0.946   0.956   1.036
224   G         0.893   0.901   0.960   0.813   0.820   0.924   0.946   0.956   1.036
225   G         0.893   0.901   0.960   0.813   0.820   0.924   0.946   0.956   1.036
226   V         0.893   0.901   0.960   0.792   0.804   0.905   0.946   0.956   1.036
227   A         0.144   0.155  -0.115  -0.090  -0.082  -0.420   0.103   0.119  -0.338
228   T         0.893   0.901   0.960   1.045   1.056   1.134   0.946   0.956   1.036
229   P         0.893   0.901   0.960   1.077   1.089   1.163   0.946   0.956   1.036
230   A         0.893   0.901   0.960   0.579   0.580   0.712   0.946   0.956   1.036
231   D         0.893   0.901   0.960   0.981   0.993   1.076   0.946   0.956   1.036
232   A         0.893   0.901   0.960   0.579   0.580   0.712   0.946   0.956   1.036
233   A         0.893   0.901   0.960   0.579   0.580   0.712   0.946   0.956   1.036
234   L         0.893   0.901   0.960   0.895   0.912   0.998   0.946   0.956   1.036
235   L        -1.077  -1.082  -0.912  -1.099  -1.097  -0.834  -1.303  -1.304  -1.051
236   M         0.893   0.901   0.960   1.035   1.046   1.125   0.946   0.956   1.036
237   Q         0.144   0.025  -0.126   0.402   0.234  -0.073   0.103  -0.083  -0.358
238   L         0.144   0.025  -0.126   0.245   0.099  -0.127   0.103  -0.083  -0.358
239   G         0.893   0.901   0.960   0.813   0.820   0.924   0.946   0.956   1.036
240   C         0.893   0.901   0.960   1.163   1.173   1.240   0.946   0.956   1.036
241   E        -0.199  -0.144  -0.178  -0.261  -0.159  -0.278  -0.459  -0.363  -0.450
242   G         0.893   0.901   0.960   0.813   0.820   0.924   0.946   0.956   1.036
243   V         0.893   0.901   0.960   0.792   0.804   0.905   0.946   0.956   1.036
244   F         0.893   0.901   0.960   1.116   1.128   1.198   0.946   0.956   1.036
245   V         0.893   0.901   0.960   0.792   0.804   0.905   0.946   0.956   1.036
246   G         0.893   0.901   0.960   0.813   0.820   0.924   0.946   0.956   1.036
247   S         0.893   0.901   0.960   1.006   1.023   1.098   0.946   0.956   1.036
248   G         0.893   0.901   0.960   0.813   0.820   0.924   0.946   0.956   1.036
249   I         0.893   0.901   0.960   0.895   0.909   0.998   0.946   0.956   1.036
250   F         0.893   0.901   0.960   1.116   1.128   1.198   0.946   0.956   1.036
251   K        -0.199  -0.184  -0.186  -0.337  -0.303  -0.347  -0.459  -0.433  -0.465
252   S        -0.561  -0.666  -0.834  -0.357  -0.500  -0.829  -0.600  -0.741  -0.951
253   S        -1.937  -1.963  -1.774  -1.963  -2.035  -1.748  -1.724  -1.735  -1.463
254   D        -0.941  -1.005  -0.882  -0.889  -0.971  -0.809  -1.162  -1.220  -1.016
255   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
256   P         0.893   0.901   0.960   1.077   1.089   1.163   0.946   0.956   1.036
257   E        -0.199  -0.184  -0.186  -0.497  -0.470  -0.544  -0.459  -0.433  -0.465
258   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
259   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
260   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
261   K        -1.214  -1.270  -1.348  -1.099  -1.166  -1.317  -1.162  -1.227  -1.258
262   L        -0.354  -0.360  -0.222  -0.537  -0.542  -0.321  -0.740  -0.753  -0.530
263   A         0.893   0.901   0.960   0.579   0.580   0.712   0.946   0.956   1.036
264   C        -0.941  -0.880  -0.876  -0.971  -0.895  -0.817  -1.162  -1.095  -1.010
265   A         0.893   0.901   0.960   0.579   0.580   0.712   0.946   0.956   1.036
266   I         0.144   0.025  -0.126   0.191   0.022  -0.264   0.103  -0.083  -0.358
267   V         0.893   0.901   0.960   0.792   0.804   0.905   0.946   0.956   1.036
268   E        -1.937  -1.963  -1.774  -1.746  -1.780  -1.504  -1.724  -1.735  -1.463
269   A         0.893   0.901   0.960   0.579   0.580   0.712   0.946   0.956   1.036
270   T        -0.354  -0.328  -0.214  -0.608  -0.567  -0.373  -0.740  -0.694  -0.516
271   T         0.144   0.025  -0.126   0.308   0.122  -0.221   0.103  -0.083  -0.358
272   H         0.144   0.025  -0.126   0.515   0.361   0.098   0.103  -0.083  -0.358
273   Y         0.144   0.025  -0.126   0.546   0.397   0.147   0.103  -0.083  -0.358
274   D        -0.941  -0.926  -0.880  -0.889  -0.849  -0.801  -1.162  -1.136  -1.013
275   N         0.144   0.230  -0.109   0.333   0.441  -0.023   0.103   0.230  -0.328
276   P        -0.561  -0.655  -0.833  -0.289  -0.411  -0.777  -0.600  -0.728  -0.949
277   A        -1.801  -1.808  -1.756  -1.928  -1.940  -1.974  -1.584  -1.588  -1.449
278   K        -1.801  -1.848  -1.761  -1.831  -1.946  -1.843  -1.584  -1.624  -1.453
279   L         0.144   0.192  -0.112   0.191   0.264  -0.237   0.103   0.174  -0.333
280   L        -1.439  -1.476  -1.381  -1.681  -1.751  -1.580  -1.443  -1.474  -1.293
281   Q        -0.852  -0.801  -0.866  -0.903  -0.821  -0.914  -1.022  -0.945  -0.995
282   V        -0.852  -0.923  -0.872  -0.972  -1.096  -1.031  -1.022  -1.097  -1.002
283   S         0.144   0.025  -0.126   0.363   0.218  -0.018   0.103  -0.083  -0.358
284   S        -1.439  -1.478  -1.376  -1.341  -1.391  -1.289  -1.443  -1.471  -1.289
285   D        -0.852  -0.934  -0.880  -0.768  -0.887  -0.835  -1.022  -1.112  -1.012
286   L         0.144   0.025  -0.126   0.254   0.111  -0.107   0.103  -0.083  -0.358
287   G         0.893   0.901   0.960   0.813   0.820   0.924   0.946   0.956   1.036
288   D        -1.439  -1.398  -1.371  -1.546  -1.473  -1.453  -1.443  -1.386  -1.283
289   L        -0.354  -0.360  -0.222  -0.815  -0.852  -0.612  -0.740  -0.753  -0.530
290   M         0.893   0.901   0.960   1.035   1.046   1.125   0.946   0.956   1.036
291   G        -1.439  -1.476  -1.381  -1.581  -1.640  -1.442  -1.443  -1.474  -1.293
292   G         0.893   0.901   0.960   0.813   0.820   0.924   0.946   0.956   1.036
293   I        -1.439  -1.394  -1.371  -1.467  -1.391  -1.382  -1.443  -1.389  -1.283
294   S        -0.561  -0.550  -0.822  -0.387  -0.364  -0.868  -0.600  -0.583  -0.934
295   I        -0.941  -1.005  -0.886  -1.135  -1.192  -0.973  -1.162  -1.220  -1.021
296   Q        -1.937  -1.933  -1.769  -1.955  -1.995  -1.709  -1.724  -1.713  -1.459
297   S         0.144   0.025  -0.126   0.305   0.139  -0.162   0.103  -0.083  -0.358
298   I        -0.852  -0.909  -0.870  -0.911  -0.965  -0.923  -1.022  -1.077  -0.999
299   N        -1.214  -1.132  -1.339  -1.057  -0.943  -1.236  -1.162  -1.063  -1.249
300   E        -1.439  -1.487  -1.372  -1.613  -1.663  -1.437  -1.443  -1.482  -1.285
301   A        -1.937  -1.884  -1.764  -1.957  -1.863  -1.713  -1.724  -1.671  -1.456
302   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
303   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
304   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
305   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
306   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
307   A        -1.214  -1.134  -1.343  -1.236  -1.101  -1.502  -1.162  -1.064  -1.253
308   R        -0.354  -0.353  -0.221  -0.549  -0.545  -0.331  -0.740  -0.740  -0.528
309   L        -0.561  -0.631  -0.831  -0.459  -0.547  -0.893  -0.600  -0.697  -0.946
310   S        -0.852  -0.792  -0.861  -1.198  -1.110  -1.162  -1.022  -0.928  -0.988
311   E        -2.299  -2.294  -2.084  -2.065  -2.070  -1.794  -1.865  -1.853  -1.568
312   I        -0.199  -0.144  -0.178  -0.198  -0.102  -0.215  -0.459  -0.363  -0.450
313   G         0.893   0.901   0.960   0.813   0.820   0.924   0.946   0.956   1.036
314   W         0.893   0.901   0.960   1.225   1.235   1.297   0.946   0.956   1.036
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P43545
Output conservation file - output/P43545
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
