1     M         0.956   0.974   1.024   1.132   1.157   1.215   1.001   1.024   1.094
2     S         0.956   0.974   1.024   1.002   1.029   1.101   1.001   1.024   1.094
3     T         0.005   0.107  -0.222   0.134   0.266  -0.213  -0.041   0.108  -0.409
4     D        -1.178  -1.109  -1.078  -1.237  -1.148  -1.075  -1.291  -1.208  -1.100
5     K         0.956   0.974   1.024   0.790   0.837   0.915   1.001   1.024   1.094
6     I         0.956   0.974   1.024   0.897   0.917   1.009   1.001   1.024   1.094
7     T         0.005   0.121  -0.219   0.134   0.284  -0.209  -0.041   0.128  -0.405
8     F         0.956   0.974   1.024   1.041   1.062   1.135   1.001   1.024   1.094
9     L         0.956   0.974   1.024   0.758   0.794   0.886   1.001   1.024   1.094
10    L        -0.875  -1.072  -1.066  -0.949  -1.236  -1.210  -0.874  -1.116  -1.084
11    N         0.956   0.974   1.024   1.066   1.088   1.157   1.001   1.024   1.094
12    W         0.956   0.974   1.024   1.205   1.228   1.280   1.001   1.024   1.094
13    Q        -1.178  -1.226  -1.084  -1.134  -1.219  -0.983  -1.291  -1.327  -1.107
14    P        -0.387  -0.244  -0.275  -0.557  -0.324  -0.380  -0.666  -0.426  -0.499
15    T        -0.387  -0.299  -0.293  -0.518  -0.368  -0.396  -0.666  -0.516  -0.528
16    P         0.956   0.974   1.024   1.010   1.037   1.108   1.001   1.024   1.094
17    Y         0.956   0.974   1.024   0.993   1.030   1.093   1.001   1.024   1.094
18    H         0.956   0.974   1.024   1.178   1.200   1.256   1.001   1.024   1.094
19    I        -1.666  -1.748  -1.644  -1.655  -1.838  -1.659  -1.499  -1.571  -1.391
20    P         0.956   0.974   1.024   1.010   1.037   1.108   1.001   1.024   1.094
21    I        -1.178  -1.175  -1.076  -1.336  -1.336  -1.186  -1.291  -1.255  -1.097
22    F        -0.387  -0.386  -0.310  -0.450  -0.451  -0.348  -0.666  -0.664  -0.559
23    L         0.005   0.121  -0.219  -0.121   0.041  -0.443  -0.041   0.128  -0.405
24    A         0.956   0.974   1.024   0.891   0.920   1.004   1.001   1.024   1.094
25    Q        -0.875  -0.731  -1.028  -0.598  -0.403  -0.851  -0.874  -0.681  -1.037
26    T        -1.666  -1.607  -1.625  -1.477  -1.416  -1.444  -1.499  -1.419  -1.374
27    K         0.005  -0.149  -0.242  -0.053  -0.246  -0.377  -0.041  -0.275  -0.443
28    G         0.956   0.974   1.024   0.857   0.880   0.973   1.001   1.024   1.094
29    Y        -0.387  -0.368  -0.308  -0.450  -0.418  -0.344  -0.666  -0.632  -0.554
30    F        -0.387  -0.402  -0.313  -0.429  -0.468  -0.347  -0.666  -0.692  -0.563
31    K         0.005  -0.149  -0.242  -0.094  -0.303  -0.469  -0.041  -0.275  -0.443
32    E        -0.875  -0.951  -1.047  -0.814  -0.926  -1.057  -0.874  -0.969  -1.060
33    Q        -0.507  -0.469  -0.320  -0.725  -0.672  -0.423  -0.874  -0.808  -0.575
34    G         0.005   0.081  -0.223   0.012   0.107  -0.296  -0.041   0.071  -0.410
35    L        -1.178  -1.011  -1.064  -1.401  -1.127  -1.188  -1.291  -1.064  -1.082
36    D        -0.875  -1.072  -1.066  -0.773  -1.076  -1.069  -0.874  -1.116  -1.084
37    M        -1.178  -0.989  -1.063  -1.206  -0.937  -0.996  -1.291  -1.048  -1.081
38    A         0.005   0.121  -0.219   0.033   0.186  -0.290  -0.041   0.128  -0.405
39    I         0.005  -0.073  -0.237  -0.009  -0.132  -0.422  -0.041  -0.156  -0.434
40    L         0.956   0.974   1.024   0.758   0.794   0.886   1.001   1.024   1.094
41    E         0.956   0.974   1.024   0.868   0.899   0.983   1.001   1.024   1.094
42    P         0.956   0.974   1.024   1.010   1.037   1.108   1.001   1.024   1.094
43    T        -1.178  -1.219  -1.083  -1.158  -1.218  -0.998  -1.291  -1.316  -1.106
44    N         0.005  -0.073  -0.237   0.190   0.075  -0.216  -0.041  -0.156  -0.434
45    P         0.956   0.974   1.024   1.010   1.037   1.108   1.001   1.024   1.094
46    S         0.956   0.974   1.024   1.002   1.029   1.101   1.001   1.024   1.094
47    D         0.956   0.974   1.024   0.923   0.950   1.031   1.001   1.024   1.094
48    V         0.956   0.974   1.024   0.985   1.014   1.086   1.001   1.024   1.094
49    T         0.956   0.974   1.024   0.993   1.018   1.093   1.001   1.024   1.094
50    E         0.005  -0.149  -0.242  -0.012  -0.235  -0.396  -0.041  -0.275  -0.443
51    L         0.005  -0.073  -0.237  -0.121  -0.223  -0.473  -0.041  -0.156  -0.434
52    I         0.005   0.081  -0.223   0.036   0.130  -0.298  -0.041   0.071  -0.410
53    G         0.956   0.974   1.024   0.857   0.880   0.973   1.001   1.024   1.094
54    S         0.956   0.974   1.024   1.002   1.029   1.101   1.001   1.024   1.094
55    G         0.956   0.974   1.024   0.857   0.880   0.973   1.001   1.024   1.094
56    K         0.956   0.974   1.024   0.790   0.837   0.915   1.001   1.024   1.094
57    V         0.005   0.121  -0.219   0.105   0.261  -0.259  -0.041   0.128  -0.405
58    D         0.956   0.974   1.024   0.923   0.950   1.031   1.001   1.024   1.094
59    M         0.005  -0.073  -0.237   0.225   0.106  -0.232  -0.041  -0.156  -0.434
60    G         0.956   0.974   1.024   0.857   0.880   0.973   1.001   1.024   1.094
61    L         0.005  -0.073  -0.237  -0.091  -0.186  -0.408  -0.041  -0.156  -0.434
62    K         0.956   0.974   1.024   0.790   0.837   0.915   1.001   1.024   1.094
63    A         0.956   0.974   1.024   0.891   0.920   1.004   1.001   1.024   1.094
64    M         0.956   0.974   1.024   1.132   1.157   1.215   1.001   1.024   1.094
65    I        -0.387  -0.292  -0.288  -0.563  -0.415  -0.410  -0.666  -0.505  -0.521
66    H         0.956   0.974   1.024   1.178   1.200   1.256   1.001   1.024   1.094
67    T         0.956   0.974   1.024   0.993   1.018   1.093   1.001   1.024   1.094
68    L         0.956   0.974   1.024   0.758   0.794   0.886   1.001   1.024   1.094
69    A         0.956   0.974   1.024   0.891   0.920   1.004   1.001   1.024   1.094
70    A         0.956   0.974   1.024   0.891   0.920   1.004   1.001   1.024   1.094
71    K         0.956   0.974   1.024   0.790   0.837   0.915   1.001   1.024   1.094
72    A         0.956   0.974   1.024   0.891   0.920   1.004   1.001   1.024   1.094
73    R         0.956   0.974   1.024   1.068   1.087   1.160   1.001   1.024   1.094
74    G         0.005  -0.073  -0.237   0.012  -0.095  -0.318  -0.041  -0.156  -0.434
75    F        -1.178  -1.025  -1.061  -1.222  -0.969  -1.066  -1.291  -1.074  -1.079
76    P         0.005   0.107  -0.222   0.135   0.272  -0.232  -0.041   0.108  -0.409
77    V         0.956   0.974   1.024   0.985   1.014   1.086   1.001   1.024   1.094
78    T         0.005  -0.073  -0.237   0.087  -0.032  -0.344  -0.041  -0.156  -0.434
79    S         0.956   0.974   1.024   1.002   1.029   1.101   1.001   1.024   1.094
80    V        -1.178  -1.191  -1.073  -1.256  -1.260  -1.062  -1.291  -1.269  -1.093
81    A        -0.387  -0.251  -0.278  -0.644  -0.419  -0.470  -0.666  -0.439  -0.503
82    S         0.956   0.974   1.024   1.002   1.029   1.101   1.001   1.024   1.094
83    L         0.956   0.974   1.024   0.758   0.794   0.886   1.001   1.024   1.094
84    L         0.956   0.974   1.024   0.758   0.794   0.886   1.001   1.024   1.094
85    D         0.005  -0.149  -0.242   0.077  -0.136  -0.275  -0.041  -0.275  -0.443
86    E         0.956   0.974   1.024   0.868   0.899   0.983   1.001   1.024   1.094
87    P         0.956   0.974   1.024   1.010   1.037   1.108   1.001   1.024   1.094
88    F         0.956   0.974   1.024   1.041   1.062   1.135   1.001   1.024   1.094
89    T         0.956   0.974   1.024   0.993   1.018   1.093   1.001   1.024   1.094
90    G         0.956   0.974   1.024   0.857   0.880   0.973   1.001   1.024   1.094
91    V        -0.875  -0.951  -1.047  -0.782  -0.927  -1.119  -0.874  -0.969  -1.060
92    L        -1.666  -1.763  -1.645  -1.669  -1.824  -1.579  -1.499  -1.585  -1.392
93    Y         0.005  -0.149  -0.242   0.132  -0.078  -0.252  -0.041  -0.275  -0.443
94    L         0.956   0.974   1.024   0.758   0.794   0.886   1.001   1.024   1.094
95    K        -0.507  -0.457  -0.316  -0.935  -0.841  -0.601  -0.874  -0.788  -0.568
96    G         0.005  -0.073  -0.237  -0.028  -0.143  -0.406  -0.041  -0.156  -0.434
97    S         0.005  -0.149  -0.242   0.155  -0.059  -0.214  -0.041  -0.275  -0.443
98    G         0.956   0.974   1.024   0.857   0.880   0.973   1.001   1.024   1.094
99    I         0.956   0.974   1.024   0.897   0.917   1.009   1.001   1.024   1.094
100   T         0.956   0.974   1.024   0.998   1.024   1.098   1.001   1.024   1.094
101   E        -2.337  -2.290  -2.090  -2.085  -2.023  -1.741  -1.916  -1.849  -1.572
102   D         0.956   0.974   1.024   0.923   0.950   1.031   1.001   1.024   1.094
103   F         0.956   0.974   1.024   1.041   1.062   1.135   1.001   1.024   1.094
104   Q        -2.337  -2.312  -2.089  -2.060  -2.074  -1.735  -1.916  -1.864  -1.571
105   S         0.005  -0.149  -0.242   0.127  -0.099  -0.276  -0.041  -0.275  -0.443
106   L         0.005  -0.149  -0.242  -0.121  -0.339  -0.481  -0.041  -0.275  -0.443
107   K         0.956   0.974   1.024   0.790   0.837   0.915   1.001   1.024   1.094
108   G         0.956   0.974   1.024   0.857   0.880   0.973   1.001   1.024   1.094
109   K         0.956   0.974   1.024   0.790   0.837   0.915   1.001   1.024   1.094
110   K        -0.507  -0.443  -0.311  -0.785  -0.637  -0.436  -0.874  -0.762  -0.559
111   I         0.956   0.974   1.024   0.897   0.917   1.009   1.001   1.024   1.094
112   G         0.956   0.974   1.024   0.857   0.880   0.973   1.001   1.024   1.094
113   Y         0.956   0.974   1.024   0.993   1.030   1.093   1.001   1.024   1.094
114   V         0.956   0.974   1.024   0.985   1.014   1.086   1.001   1.024   1.094
115   G         0.956   0.974   1.024   0.857   0.880   0.973   1.001   1.024   1.094
116   E         0.956   0.974   1.024   0.868   0.899   0.983   1.001   1.024   1.094
117   F         0.956   0.974   1.024   1.041   1.062   1.135   1.001   1.024   1.094
118   G         0.956   0.974   1.024   0.857   0.880   0.973   1.001   1.024   1.094
119   K         0.956   0.974   1.024   0.790   0.837   0.915   1.001   1.024   1.094
120   I         0.956   0.974   1.024   0.897   0.917   1.009   1.001   1.024   1.094
121   Q         0.956   0.974   1.024   1.074   1.101   1.165   1.001   1.024   1.094
122   I        -0.875  -0.951  -1.047  -0.847  -0.998  -1.144  -0.874  -0.969  -1.060
123   D         0.956   0.974   1.024   0.923   0.950   1.031   1.001   1.024   1.094
124   E         0.005  -0.149  -0.242  -0.005  -0.226  -0.382  -0.041  -0.275  -0.443
125   L         0.956   0.974   1.024   0.758   0.794   0.886   1.001   1.024   1.094
126   T         0.005  -0.149  -0.242   0.157  -0.053  -0.197  -0.041  -0.275  -0.443
127   K        -0.387  -0.452  -0.319  -0.653  -0.747  -0.520  -0.666  -0.777  -0.574
128   H         0.005  -0.149  -0.242   0.277   0.036  -0.192  -0.041  -0.275  -0.443
129   Y         0.005  -0.149  -0.242   0.142  -0.066  -0.231  -0.041  -0.275  -0.443
130   G         0.956   0.974   1.024   0.857   0.880   0.973   1.001   1.024   1.094
131   M        -0.387  -0.452  -0.319  -0.449  -0.626  -0.440  -0.666  -0.777  -0.574
132   K        -1.178  -1.196  -1.075  -1.295  -1.277  -1.116  -1.291  -1.275  -1.095
133   P         0.956   0.974   1.024   1.010   1.037   1.108   1.001   1.024   1.094
134   E        -2.337  -2.290  -2.090  -2.244  -2.186  -1.887  -1.916  -1.849  -1.572
135   D         0.956   0.974   1.024   0.923   0.950   1.031   1.001   1.024   1.094
136   Y         0.956   0.974   1.024   0.993   1.030   1.093   1.001   1.024   1.094
137   T        -0.875  -0.731  -1.028  -0.726  -0.526  -0.995  -0.874  -0.681  -1.037
138   A         0.005   0.121  -0.219   0.035   0.188  -0.287  -0.041   0.128  -0.405
139   V         0.005  -0.149  -0.242   0.105  -0.123  -0.301  -0.041  -0.275  -0.443
140   R         0.956   0.974   1.024   1.068   1.087   1.160   1.001   1.024   1.094
141   C         0.956   0.974   1.024   1.118   1.145   1.203   1.001   1.024   1.094
142   G         0.956   0.974   1.024   0.857   0.880   0.973   1.001   1.024   1.094
143   M         0.956   0.974   1.024   1.132   1.157   1.215   1.001   1.024   1.094
144   N         0.956   0.974   1.024   1.066   1.088   1.157   1.001   1.024   1.094
145   V         0.005  -0.149  -0.242   0.105  -0.123  -0.301  -0.041  -0.275  -0.443
146   A         0.005  -0.073  -0.237   0.033  -0.070  -0.320  -0.041  -0.156  -0.434
147   K         0.005  -0.149  -0.242  -0.065  -0.261  -0.404  -0.041  -0.275  -0.443
148   Y        -0.387  -0.452  -0.319  -0.518  -0.655  -0.454  -0.666  -0.777  -0.574
149   I         0.956   0.974   1.024   0.897   0.917   1.009   1.001   1.024   1.094
150   I         0.005   0.081  -0.223  -0.009   0.091  -0.394  -0.041   0.071  -0.410
151   E        -0.875  -1.072  -1.066  -0.847  -1.139  -1.145  -0.874  -1.116  -1.084
152   G         0.956   0.974   1.024   0.857   0.880   0.973   1.001   1.024   1.094
153   K        -1.178  -1.143  -1.085  -1.428  -1.377  -1.229  -1.291  -1.246  -1.108
154   I         0.956   0.974   1.024   0.897   0.917   1.009   1.001   1.024   1.094
155   D         0.956   0.974   1.024   0.923   0.950   1.031   1.001   1.024   1.094
156   A        -0.875  -0.951  -1.047  -0.795  -0.932  -1.047  -0.874  -0.969  -1.060
157   G         0.956   0.974   1.024   0.857   0.880   0.973   1.001   1.024   1.094
158   I         0.005   0.107  -0.222   0.036   0.163  -0.297  -0.041   0.108  -0.409
159   G         0.956   0.974   1.024   0.857   0.880   0.973   1.001   1.024   1.094
160   I         0.005  -0.073  -0.237  -0.009  -0.132  -0.422  -0.041  -0.156  -0.434
161   E         0.956   0.974   1.024   0.868   0.899   0.983   1.001   1.024   1.094
162   C         0.005  -0.073  -0.237   0.270   0.164  -0.115  -0.041  -0.156  -0.434
163   M        -1.178  -1.171  -1.076  -1.124  -1.096  -0.982  -1.291  -1.249  -1.096
164   Q         0.956   0.974   1.024   1.074   1.101   1.165   1.001   1.024   1.094
165   Q         0.005  -0.073  -0.237   0.239   0.138  -0.121  -0.041  -0.156  -0.434
166   V         0.956   0.974   1.024   0.985   1.014   1.086   1.001   1.024   1.094
167   E         0.005   0.107  -0.222   0.025   0.160  -0.282  -0.041   0.108  -0.409
168   L         0.956   0.974   1.024   0.758   0.794   0.886   1.001   1.024   1.094
169   E         0.956   0.974   1.024   0.868   0.899   0.983   1.001   1.024   1.094
170   E        -0.875  -0.918  -1.043  -0.814  -0.882  -1.051  -0.874  -0.931  -1.055
171   Y        -1.178  -1.143  -1.085  -1.095  -1.024  -0.952  -1.291  -1.246  -1.108
172   L         0.005  -0.149  -0.242  -0.075  -0.269  -0.379  -0.041  -0.275  -0.443
173   A        -1.850  -1.825  -1.647  -1.948  -1.899  -1.589  -1.708  -1.655  -1.395
174   K        -1.362  -1.274  -1.103  -1.656  -1.468  -1.224  -1.499  -1.372  -1.127
175   Q         0.005   0.107  -0.222   0.173   0.316  -0.234  -0.041   0.108  -0.409
176   G         0.956   0.974   1.024   0.857   0.880   0.973   1.001   1.024   1.094
177   R         0.005   0.081  -0.223   0.168   0.268  -0.240  -0.041   0.071  -0.410
178   P        -0.507  -0.472  -0.321  -0.733  -0.680  -0.428  -0.874  -0.813  -0.576
179   A        -2.824  -2.716  -2.452  -2.643  -2.484  -2.111  -2.124  -2.009  -1.689
180   S        -1.666  -1.607  -1.625  -1.521  -1.443  -1.509  -1.499  -1.419  -1.374
181   D         0.956   0.974   1.024   0.923   0.950   1.031   1.001   1.024   1.094
182   A        -0.387  -0.452  -0.319  -0.569  -0.688  -0.464  -0.666  -0.777  -0.574
183   K        -0.387  -0.452  -0.319  -0.619  -0.701  -0.474  -0.666  -0.777  -0.574
184   M         0.956   0.974   1.024   1.132   1.157   1.215   1.001   1.024   1.094
185   L         0.956   0.974   1.024   0.758   0.794   0.886   1.001   1.024   1.094
186   R         0.956   0.974   1.024   1.068   1.087   1.160   1.001   1.024   1.094
187   I         0.956   0.974   1.024   0.897   0.917   1.009   1.001   1.024   1.094
188   D         0.956   0.974   1.024   0.923   0.950   1.031   1.001   1.024   1.094
189   K        -1.178  -1.255  -1.087  -1.405  -1.485  -1.198  -1.291  -1.355  -1.110
190   L         0.956   0.974   1.024   0.758   0.794   0.886   1.001   1.024   1.094
191   A         0.956   0.974   1.024   0.891   0.920   1.004   1.001   1.024   1.094
192   C        -1.178  -1.196  -1.075  -1.197  -1.210  -1.004  -1.291  -1.275  -1.095
193   L         0.956   0.974   1.024   0.758   0.794   0.886   1.001   1.024   1.094
194   G         0.956   0.974   1.024   0.857   0.880   0.973   1.001   1.024   1.094
195   C         0.956   0.974   1.024   1.118   1.145   1.203   1.001   1.024   1.094
196   C         0.956   0.974   1.024   1.118   1.145   1.203   1.001   1.024   1.094
197   C         0.956   0.974   1.024   1.118   1.145   1.203   1.001   1.024   1.094
198   F         0.956   0.974   1.024   1.041   1.062   1.135   1.001   1.024   1.094
199   C         0.956   0.974   1.024   1.118   1.145   1.203   1.001   1.024   1.094
200   T         0.005  -0.073  -0.237   0.134   0.026  -0.240  -0.041  -0.156  -0.434
201   V         0.005   0.175  -0.213   0.036   0.246  -0.283  -0.041   0.202  -0.395
202   L         0.956   0.974   1.024   0.758   0.794   0.886   1.001   1.024   1.094
203   Y         0.956   0.974   1.024   0.993   1.030   1.093   1.001   1.024   1.094
204   I         0.956   0.974   1.024   0.897   0.917   1.009   1.001   1.024   1.094
205   C        -1.178  -1.139  -1.067  -1.237  -1.183  -1.065  -1.291  -1.206  -1.085
206   N         0.005  -0.149  -0.242   0.240   0.030  -0.115  -0.041  -0.275  -0.443
207   D         0.005  -0.073  -0.237   0.038  -0.074  -0.353  -0.041  -0.156  -0.434
208   E        -1.178  -1.175  -1.076  -1.405  -1.366  -1.210  -1.291  -1.255  -1.097
209   F         0.956   0.974   1.024   1.041   1.062   1.135   1.001   1.024   1.094
210   L        -0.507  -0.443  -0.311  -0.937  -0.808  -0.579  -0.874  -0.762  -0.559
211   K        -1.178  -1.139  -1.067  -1.383  -1.274  -1.171  -1.291  -1.206  -1.085
212   K        -1.850  -1.797  -1.644  -1.995  -1.897  -1.640  -1.708  -1.628  -1.393
213   N         0.005  -0.149  -0.242   0.240   0.030  -0.115  -0.041  -0.275  -0.443
214   P         0.005   0.081  -0.223   0.151   0.253  -0.201  -0.041   0.071  -0.410
215   E        -1.850  -1.706  -1.644  -1.870  -1.653  -1.523  -1.708  -1.536  -1.392
216   K         0.005   0.081  -0.223  -0.090   0.033  -0.425  -0.041   0.071  -0.410
217   V         0.005  -0.149  -0.242   0.105  -0.123  -0.301  -0.041  -0.275  -0.443
218   R        -0.387  -0.348  -0.304  -0.621  -0.549  -0.465  -0.666  -0.599  -0.547
219   K        -0.387  -0.452  -0.319  -0.706  -0.817  -0.591  -0.666  -0.777  -0.574
220   F         0.956   0.974   1.024   1.041   1.062   1.135   1.001   1.024   1.094
221   L         0.005  -0.073  -0.237  -0.072  -0.161  -0.366  -0.041  -0.156  -0.434
222   K        -1.178  -1.128  -1.085  -1.290  -1.202  -1.075  -1.291  -1.232  -1.108
223   A         0.956   0.974   1.024   0.891   0.920   1.004   1.001   1.024   1.094
224   I        -0.875  -0.853  -1.038  -0.790  -0.776  -1.028  -0.874  -0.842  -1.048
225   K         0.005  -0.149  -0.242  -0.030  -0.212  -0.326  -0.041  -0.275  -0.443
226   K        -1.178  -1.219  -1.080  -1.308  -1.346  -1.111  -1.291  -1.306  -1.101
227   A         0.956   0.974   1.024   0.891   0.920   1.004   1.001   1.024   1.094
228   T         0.956   0.974   1.024   0.993   1.018   1.093   1.001   1.024   1.094
229   D         0.005  -0.149  -0.242   0.016  -0.221  -0.411  -0.041  -0.275  -0.443
230   Y        -1.666  -1.748  -1.644  -1.537  -1.675  -1.559  -1.499  -1.571  -1.391
231   V        -1.178  -1.109  -1.078  -1.141  -1.050  -0.988  -1.291  -1.208  -1.100
232   L         0.956   0.974   1.024   0.758   0.794   0.886   1.001   1.024   1.094
233   A        -0.875  -0.930  -1.045  -0.822  -0.931  -1.092  -0.874  -0.945  -1.058
234   D        -1.178  -1.171  -1.076  -1.120  -1.106  -0.939  -1.291  -1.249  -1.096
235   P         0.956   0.974   1.024   1.010   1.037   1.108   1.001   1.024   1.094
236   V        -2.337  -2.230  -2.079  -2.235  -2.071  -1.876  -1.916  -1.793  -1.563
237   K        -1.666  -1.558  -1.617  -1.515  -1.355  -1.527  -1.499  -1.370  -1.366
238   A         0.005  -0.149  -0.242   0.032  -0.185  -0.332  -0.041  -0.275  -0.443
239   W         0.005  -0.149  -0.242   0.341   0.116  -0.087  -0.041  -0.275  -0.443
240   K        -0.875  -0.718  -1.027  -0.949  -0.709  -1.183  -0.874  -0.665  -1.035
241   E         0.005   0.107  -0.222  -0.005   0.133  -0.346  -0.041   0.108  -0.409
242   Y         0.956   0.974   1.024   0.993   1.030   1.093   1.001   1.024   1.094
243   I        -1.850  -1.737  -1.640  -1.877  -1.731  -1.554  -1.708  -1.577  -1.389
244   D        -0.875  -0.951  -1.047  -0.699  -0.805  -0.912  -0.874  -0.969  -1.060
245   F         0.956   0.974   1.024   1.041   1.062   1.135   1.001   1.024   1.094
246   K         0.956   0.974   1.024   0.790   0.837   0.915   1.001   1.024   1.094
247   P         0.005  -0.149  -0.242   0.164  -0.052  -0.206  -0.041  -0.275  -0.443
248   Q        -1.666  -1.763  -1.645  -1.426  -1.616  -1.459  -1.499  -1.585  -1.392
249   L        -0.387  -0.251  -0.278  -0.449  -0.196  -0.323  -0.666  -0.439  -0.503
250   N        -1.850  -1.701  -1.644  -1.777  -1.603  -1.459  -1.708  -1.532  -1.392
251   N        -1.850  -1.696  -1.639  -1.756  -1.561  -1.438  -1.708  -1.543  -1.388
252   D        -1.178  -1.022  -1.064  -1.325  -1.083  -1.113  -1.291  -1.076  -1.082
253   L         0.956   0.974   1.024   0.758   0.794   0.886   1.001   1.024   1.094
254   S        -1.178  -1.196  -1.075  -1.070  -1.063  -0.891  -1.291  -1.275  -1.095
255   Y        -1.850  -1.701  -1.644  -1.709  -1.486  -1.405  -1.708  -1.532  -1.392
256   K         0.005  -0.149  -0.242  -0.094  -0.303  -0.469  -0.041  -0.275  -0.443
257   Q        -1.666  -1.597  -1.625  -1.433  -1.350  -1.432  -1.499  -1.409  -1.373
258   Y         0.005   0.175  -0.213   0.179   0.393  -0.164  -0.041   0.202  -0.395
259   Q        -0.507  -0.450  -0.313  -0.725  -0.648  -0.418  -0.874  -0.774  -0.563
260   R         0.956   0.974   1.024   1.068   1.087   1.160   1.001   1.024   1.094
261   C         0.005  -0.073  -0.237   0.257   0.149  -0.142  -0.041  -0.156  -0.434
262   Y        -0.507  -0.470  -0.320  -0.660  -0.601  -0.363  -0.874  -0.811  -0.575
263   A         0.956   0.974   1.024   0.891   0.920   1.004   1.001   1.024   1.094
264   Y         0.956   0.974   1.024   0.993   1.030   1.093   1.001   1.024   1.094
265   F         0.956   0.974   1.024   1.041   1.062   1.135   1.001   1.024   1.094
266   S         0.956   0.974   1.024   1.002   1.029   1.101   1.001   1.024   1.094
267   S        -1.850  -1.816  -1.647  -1.800  -1.734  -1.472  -1.708  -1.645  -1.395
268   S        -0.387  -0.452  -0.319  -0.496  -0.638  -0.429  -0.666  -0.777  -0.574
269   L         0.005  -0.149  -0.242  -0.121  -0.339  -0.481  -0.041  -0.275  -0.443
270   Y        -0.875  -1.072  -1.066  -0.741  -1.039  -1.088  -0.874  -1.116  -1.084
271   N         0.956   0.974   1.024   1.066   1.088   1.157   1.001   1.024   1.094
272   V         0.956   0.974   1.024   0.985   1.014   1.086   1.001   1.024   1.094
273   H        -0.875  -1.072  -1.066  -0.542  -0.862  -0.924  -0.874  -1.116  -1.084
274   R         0.956   0.974   1.024   1.068   1.087   1.160   1.001   1.024   1.094
275   D         0.956   0.974   1.024   0.923   0.950   1.031   1.001   1.024   1.094
276   W         0.956   0.974   1.024   1.205   1.228   1.280   1.001   1.024   1.094
277   K        -1.850  -1.894  -1.654  -1.819  -1.846  -1.491  -1.708  -1.711  -1.401
278   K         0.956   0.974   1.024   0.790   0.837   0.915   1.001   1.024   1.094
279   V         0.956   0.974   1.024   0.985   1.014   1.086   1.001   1.024   1.094
280   T         0.005   0.081  -0.223   0.147   0.244  -0.188  -0.041   0.071  -0.410
281   G        -1.850  -1.763  -1.642  -1.897  -1.760  -1.594  -1.708  -1.598  -1.391
282   Y         0.956   0.974   1.024   0.993   1.030   1.093   1.001   1.024   1.094
283   G         0.005  -0.149  -0.242  -0.001  -0.222  -0.355  -0.041  -0.275  -0.443
284   K         0.005  -0.073  -0.237  -0.052  -0.134  -0.367  -0.041  -0.156  -0.434
285   R         0.956   0.974   1.024   1.068   1.087   1.160   1.001   1.024   1.094
286   L         0.956   0.974   1.024   0.758   0.794   0.886   1.001   1.024   1.094
287   A        -1.850  -1.664  -1.643  -1.984  -1.726  -1.659  -1.708  -1.506  -1.392
288   I         0.005  -0.073  -0.237   0.036  -0.077  -0.323  -0.041  -0.156  -0.434
289   L         0.005  -0.149  -0.242  -0.121  -0.339  -0.481  -0.041  -0.275  -0.443
290   P         0.005  -0.073  -0.237   0.151   0.045  -0.226  -0.041  -0.156  -0.434
291   P        -1.666  -1.655  -1.631  -1.457  -1.450  -1.436  -1.499  -1.475  -1.379
292   D         0.005   0.081  -0.223   0.077   0.176  -0.244  -0.041   0.071  -0.410
293   Y        -0.507  -0.447  -0.312  -0.660  -0.554  -0.345  -0.874  -0.770  -0.561
294   V        -1.850  -1.796  -1.643  -1.922  -1.838  -1.608  -1.708  -1.625  -1.392
295   S        -0.507  -0.443  -0.311  -0.676  -0.566  -0.359  -0.874  -0.762  -0.559
296   N         0.956   0.974   1.024   1.066   1.088   1.157   1.001   1.024   1.094
297   Y         0.005  -0.149  -0.242   0.157  -0.041  -0.197  -0.041  -0.275  -0.443
298   T         0.005   0.121  -0.219   0.134   0.284  -0.209  -0.041   0.128  -0.405
299   N         0.956   0.974   1.024   1.066   1.088   1.157   1.001   1.024   1.094
300   E         0.005  -0.149  -0.242  -0.019  -0.247  -0.411  -0.041  -0.275  -0.443
301   Y         0.005  -0.073  -0.237   0.142   0.046  -0.223  -0.041  -0.156  -0.434
302   L         0.956   0.974   1.024   0.758   0.794   0.886   1.001   1.024   1.094
303   S        -0.875  -1.072  -1.066  -0.703  -1.009  -1.028  -0.874  -1.116  -1.084
304   W         0.956   0.974   1.024   1.205   1.228   1.280   1.001   1.024   1.094
305   P        -1.178  -1.225  -1.084  -1.268  -1.360  -1.141  -1.291  -1.324  -1.107
306   E        -0.387  -0.452  -0.319  -0.695  -0.844  -0.622  -0.666  -0.777  -0.574
307   P        -0.875  -1.072  -1.066  -0.676  -0.978  -0.986  -0.874  -1.116  -1.084
308   E        -1.850  -1.670  -1.644  -1.931  -1.634  -1.593  -1.708  -1.510  -1.392
309   E         0.005  -0.149  -0.242  -0.005  -0.226  -0.382  -0.041  -0.275  -0.443
310   V        -0.875  -1.072  -1.066  -0.730  -1.041  -1.060  -0.874  -1.116  -1.084
311   S        -1.850  -1.825  -1.647  -1.916  -1.895  -1.623  -1.708  -1.655  -1.395
312   D         0.956   0.974   1.024   0.923   0.950   1.031   1.001   1.024   1.094
313   P         0.956   0.974   1.024   1.010   1.037   1.108   1.001   1.024   1.094
314   L        -1.850  -1.835  -1.648  -1.915  -1.843  -1.565  -1.708  -1.661  -1.395
315   E        -1.666  -1.427  -1.609  -1.721  -1.359  -1.665  -1.499  -1.220  -1.358
316   A        -0.875  -1.072  -1.066  -0.860  -1.177  -1.197  -0.874  -1.116  -1.084
317   Q         0.956   0.974   1.024   1.074   1.101   1.165   1.001   1.024   1.094
318   R        -2.337  -2.321  -2.093  -2.169  -2.210  -1.858  -1.916  -1.871  -1.574
319   L        -0.875  -1.072  -1.066  -0.930  -1.217  -1.174  -0.874  -1.116  -1.084
320   M        -0.387  -0.406  -0.314  -0.388  -0.451  -0.342  -0.666  -0.699  -0.565
321   A        -1.850  -1.803  -1.645  -2.072  -1.971  -1.723  -1.708  -1.633  -1.393
322   I        -1.850  -1.670  -1.644  -2.061  -1.778  -1.713  -1.708  -1.510  -1.392
323   H        -0.875  -1.072  -1.066  -0.593  -0.936  -1.020  -0.874  -1.116  -1.084
324   Q         0.956   0.974   1.024   1.074   1.101   1.165   1.001   1.024   1.094
325   E        -0.875  -1.072  -1.066  -0.883  -1.192  -1.213  -0.874  -1.116  -1.084
326   K        -1.666  -1.540  -1.620  -1.646  -1.450  -1.589  -1.499  -1.351  -1.368
327   C        -0.875  -1.072  -1.066  -0.599  -0.919  -0.964  -0.874  -1.116  -1.084
328   R        -1.178  -1.145  -1.071  -1.340  -1.278  -1.149  -1.291  -1.214  -1.090
329   Q        -2.337  -2.230  -2.079  -2.018  -1.859  -1.672  -1.916  -1.793  -1.563
330   E        -1.666  -1.591  -1.625  -1.419  -1.346  -1.439  -1.499  -1.413  -1.374
331   G         0.956   0.974   1.024   0.857   0.880   0.973   1.001   1.024   1.094
332   T         0.005   0.175  -0.213  -0.003   0.209  -0.311  -0.041   0.202  -0.395
333   F        -1.178  -1.219  -1.080  -1.148  -1.198  -0.999  -1.291  -1.306  -1.101
334   K        -1.850  -1.789  -1.643  -1.776  -1.654  -1.417  -1.708  -1.618  -1.391
335   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
336   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
337   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
339   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
340   R         0.956   0.974   1.024   1.068   1.087   1.160   1.001   1.024   1.094
341   L        -0.875  -0.930  -1.045  -0.925  -1.003  -1.139  -0.874  -0.945  -1.058
342   A        -1.850  -1.789  -1.643  -1.874  -1.762  -1.548  -1.708  -1.617  -1.391
343   L        -0.875  -0.918  -1.043  -0.957  -1.036  -1.191  -0.874  -0.931  -1.055
344   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
345   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
346   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
347   A        -1.666  -1.629  -1.624  -1.666  -1.647  -1.637  -1.499  -1.449  -1.373
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P43534
Output conservation file - output/P43534
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
