1     M         1.027   1.050   1.108   1.289   1.312   1.376   1.081   1.112   1.199
2     P        -1.544  -1.547  -1.408  -1.646  -1.653  -1.442  -1.492  -1.451  -1.238
3     R         0.256   0.094  -0.058   0.437   0.226  -0.021   0.263   0.022  -0.256
4     D        -0.816  -0.881  -0.855  -0.857  -0.924  -0.883  -0.907  -0.962  -0.923
5     P        -0.930  -0.931  -0.886  -0.929  -0.975  -0.907  -1.057  -1.075  -0.964
6     L        -0.198  -0.129  -0.127  -0.565  -0.441  -0.458  -0.446  -0.339  -0.375
7     I         1.027   1.050   1.108   1.021   1.049   1.147   1.081   1.112   1.199
8     G         0.187   0.257  -0.067   0.124   0.222  -0.246   0.165   0.263  -0.271
9     I        -0.930  -1.045  -0.890  -1.061  -1.208  -0.992  -1.057  -1.177  -0.967
10    V         1.027   1.050   1.108   0.893   0.927   1.037   1.081   1.112   1.199
11    G         1.027   1.050   1.108   0.885   0.921   1.030   1.081   1.112   1.199
12    K         0.256   0.094  -0.058   0.295   0.096  -0.133   0.263   0.022  -0.256
13    P         1.027   1.050   1.108   1.113   1.143   1.225   1.081   1.112   1.199
14    S         0.256   0.094  -0.058   0.430   0.220  -0.035   0.263   0.022  -0.256
15    S        -0.479  -0.564  -0.810  -0.279  -0.420  -0.847  -0.439  -0.557  -0.864
16    G         0.256   0.094  -0.058   0.234   0.039  -0.184   0.263   0.022  -0.256
17    K         0.256   0.094  -0.058   0.319   0.134  -0.067   0.263   0.022  -0.256
18    S         0.256   0.094  -0.058   0.419   0.205  -0.064   0.263   0.022  -0.256
19    T         0.256   0.094  -0.058   0.356   0.158  -0.092   0.263   0.022  -0.256
20    T        -0.479  -0.761  -0.843  -0.287  -0.658  -0.803  -0.439  -0.801  -0.907
21    L         1.027   1.050   1.108   0.837   0.883   0.989   1.081   1.112   1.199
22    N         0.256   0.094  -0.058   0.441   0.213  -0.065   0.263   0.022  -0.256
23    S        -0.816  -0.976  -0.874  -0.750  -1.001  -0.869  -0.907  -1.097  -0.951
24    L         0.256   0.094  -0.058   0.151  -0.050  -0.300   0.263   0.022  -0.256
25    T         0.256   0.094  -0.058   0.360   0.163  -0.082   0.263   0.022  -0.256
26    D         1.027   1.050   1.108   0.936   0.967   1.074   1.081   1.112   1.199
27    A         0.256   0.094  -0.058   0.331   0.116  -0.113   0.263   0.022  -0.256
28    G        -2.166  -2.055  -1.838  -2.035  -1.846  -1.568  -1.843  -1.716  -1.423
29    A         0.256   0.094  -0.058   0.311   0.087  -0.168   0.263   0.022  -0.256
30    A        -1.457  -1.331  -1.383  -1.469  -1.285  -1.330  -1.375  -1.212  -1.212
31    V        -0.968  -0.894  -0.874  -1.165  -1.035  -0.907  -1.141  -1.046  -0.950
32    G         0.256   0.094  -0.058   0.210   0.004  -0.248   0.263   0.022  -0.256
33    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    A        -1.102  -1.084  -0.909  -1.212  -1.196  -0.919  -1.258  -1.234  -0.990
37    F         1.027   1.050   1.108   1.175   1.200   1.279   1.081   1.112   1.199
38    P         0.256   0.094  -0.058   0.455   0.248  -0.008   0.263   0.022  -0.256
39    F         1.027   1.050   1.108   1.175   1.200   1.279   1.081   1.112   1.199
40    T         1.027   1.050   1.108   1.018   1.057   1.144   1.081   1.112   1.199
41    T         1.027   1.050   1.108   1.018   1.057   1.144   1.081   1.112   1.199
42    I         1.027   1.050   1.108   1.022   1.050   1.147   1.081   1.112   1.199
43    E        -0.392  -0.334  -0.166  -0.692  -0.605  -0.324  -0.790  -0.696  -0.444
44    P         1.027   1.050   1.108   1.113   1.143   1.225   1.081   1.112   1.199
45    N         0.256   0.094  -0.058   0.481   0.273   0.043   0.263   0.022  -0.256
46    Q        -0.968  -0.833  -0.867  -1.077  -0.909  -0.844  -1.141  -1.000  -0.943
47    A         1.027   1.050   1.108   0.993   1.015   1.123   1.081   1.112   1.199
48    T        -0.124  -0.261  -0.155  -0.200  -0.444  -0.301  -0.322  -0.565  -0.426
49    G         1.027   1.050   1.108   0.893   0.932   1.037   1.081   1.112   1.199
50    Y         1.027   1.050   1.108   1.255   1.280   1.347   1.081   1.112   1.199
51    L         0.256   0.114  -0.060   0.160  -0.010  -0.280   0.263   0.053  -0.259
52    Q        -0.124  -0.033  -0.102   0.033   0.170  -0.002  -0.322  -0.180  -0.332
53    V        -0.392  -0.297  -0.153  -0.788  -0.593  -0.366  -0.790  -0.631  -0.421
54    E        -0.816  -0.698  -0.853  -0.855  -0.714  -0.878  -0.907  -0.774  -0.924
55    C         1.027   1.050   1.108   1.287   1.308   1.375   1.081   1.112   1.199
56    A         1.027   1.050   1.108   0.993   1.015   1.123   1.081   1.112   1.199
57    C         1.027   1.050   1.108   1.287   1.308   1.375   1.081   1.112   1.199
58    S        -0.392  -0.334  -0.166  -0.660  -0.574  -0.295  -0.790  -0.696  -0.444
59    R         1.027   1.050   1.108   1.095   1.121   1.210   1.081   1.112   1.199
60    F        -0.479  -0.507  -0.810  -0.145  -0.183  -0.669  -0.439  -0.491  -0.864
61    G        -0.816  -0.836  -0.862  -0.921  -0.955  -0.971  -0.907  -0.943  -0.936
62    K        -1.102  -1.121  -0.912  -1.464  -1.520  -1.205  -1.258  -1.275  -0.994
63    E        -0.816  -0.784  -0.832  -0.584  -0.508  -0.650  -0.907  -0.831  -0.893
64    D        -1.544  -1.373  -1.387  -1.617  -1.385  -1.371  -1.492  -1.313  -1.220
65    L        -0.968  -1.040  -0.873  -1.293  -1.337  -1.052  -1.141  -1.191  -0.949
66    C         1.027   1.050   1.108   1.287   1.308   1.375   1.081   1.112   1.199
67    K         1.027   1.050   1.108   0.952   0.989   1.088   1.081   1.112   1.199
68    P         1.027   1.050   1.108   1.113   1.143   1.225   1.081   1.112   1.199
69    N         0.256   0.114  -0.060   0.451   0.256  -0.041   0.263   0.053  -0.259
70    Y         1.027   1.050   1.108   1.255   1.280   1.347   1.081   1.112   1.199
71    G         1.027   1.050   1.108   0.893   0.932   1.037   1.081   1.112   1.199
72    W        -2.032  -2.106  -1.846  -1.626  -1.775  -1.477  -1.726  -1.747  -1.428
73    C         1.027   1.050   1.108   1.287   1.308   1.375   1.081   1.112   1.199
74    S        -2.166  -2.055  -1.838  -2.142  -2.024  -1.683  -1.843  -1.716  -1.423
75    K        -1.102  -0.900  -0.864  -1.240  -0.900  -0.911  -1.258  -0.988  -0.934
76    G         1.027   1.050   1.108   0.893   0.932   1.037   1.081   1.112   1.199
77    K        -1.171  -1.158  -1.370  -1.082  -1.076  -1.441  -1.024  -1.012  -1.198
78    R         1.027   1.050   1.108   1.095   1.121   1.210   1.081   1.112   1.199
79    H        -1.678  -1.605  -1.430  -1.564  -1.484  -1.232  -1.609  -1.511  -1.258
80    I        -0.392  -0.334  -0.166  -0.788  -0.695  -0.405  -0.790  -0.696  -0.444
81    P         1.027   1.050   1.108   1.113   1.143   1.225   1.081   1.112   1.199
82    I         1.027   1.050   1.108   1.022   1.050   1.147   1.081   1.112   1.199
83    K        -1.171  -1.294  -1.386  -0.662  -0.853  -1.068  -1.024  -1.172  -1.214
84    L         1.027   1.050   1.108   0.837   0.883   0.989   1.081   1.112   1.199
85    L         1.027   1.050   1.108   0.837   0.883   0.989   1.081   1.112   1.199
86    D         1.027   1.050   1.108   0.936   0.967   1.074   1.081   1.112   1.199
87    V         1.027   1.050   1.108   0.889   0.922   1.034   1.081   1.112   1.199
88    A         1.027   1.050   1.108   0.993   1.015   1.123   1.081   1.112   1.199
89    G         1.027   1.050   1.108   0.893   0.932   1.037   1.081   1.112   1.199
90    L         1.027   1.050   1.108   0.837   0.883   0.989   1.081   1.112   1.199
91    V         0.256   0.114  -0.060   0.217   0.037  -0.226   0.263   0.053  -0.259
92    P         1.027   1.050   1.108   1.113   1.143   1.225   1.081   1.112   1.199
93    G        -0.124  -0.033  -0.102  -0.287  -0.144  -0.250  -0.322  -0.180  -0.332
94    A         1.027   1.050   1.108   0.993   1.015   1.123   1.081   1.112   1.199
95    H         1.027   1.050   1.108   1.280   1.302   1.369   1.081   1.112   1.199
96    S        -2.032  -2.106  -1.846  -1.933  -2.033  -1.644  -1.726  -1.747  -1.428
97    G         1.027   1.050   1.108   0.893   0.932   1.037   1.081   1.112   1.199
98    R        -0.328  -0.337  -0.167  -0.532  -0.587  -0.319  -0.673  -0.702  -0.447
99    G         1.027   1.050   1.108   0.893   0.932   1.037   1.081   1.112   1.199
100   L         1.027   1.050   1.108   0.837   0.883   0.989   1.081   1.112   1.199
101   G         1.027   1.050   1.108   0.893   0.932   1.037   1.081   1.112   1.199
102   N         1.027   1.050   1.108   1.123   1.143   1.234   1.081   1.112   1.199
103   K         1.027   1.050   1.108   0.952   0.989   1.088   1.081   1.112   1.199
104   F         1.027   1.050   1.108   1.175   1.200   1.279   1.081   1.112   1.199
105   L         1.027   1.050   1.108   0.837   0.883   0.989   1.081   1.112   1.199
106   D        -0.479  -0.354  -0.804  -0.409  -0.242  -0.895  -0.439  -0.276  -0.856
107   D         1.027   1.050   1.108   0.936   0.967   1.074   1.081   1.112   1.199
108   L         1.027   1.050   1.108   0.837   0.883   0.989   1.081   1.112   1.199
109   R        -0.124  -0.033  -0.102  -0.126   0.015  -0.143  -0.322  -0.180  -0.332
110   H        -0.124  -0.033  -0.102   0.078   0.210   0.033  -0.322  -0.180  -0.332
111   A         1.027   1.050   1.108   0.993   1.015   1.123   1.081   1.112   1.199
112   D         1.027   1.050   1.108   0.936   0.967   1.074   1.081   1.112   1.199
113   A        -0.124  -0.033  -0.102  -0.136  -0.013  -0.100  -0.322  -0.180  -0.332
114   L         1.027   1.050   1.108   0.837   0.883   0.989   1.081   1.112   1.199
115   I         0.256   0.114  -0.060   0.331   0.137  -0.173   0.263   0.053  -0.259
116   H         1.027   1.050   1.108   1.280   1.302   1.369   1.081   1.112   1.199
117   V        -0.124  -0.033  -0.102  -0.325  -0.182  -0.299  -0.322  -0.180  -0.332
118   V         1.027   1.050   1.108   0.889   0.922   1.034   1.081   1.112   1.199
119   D         1.027   1.050   1.108   0.936   0.967   1.074   1.081   1.112   1.199
120   V        -0.124  -0.177  -0.147  -0.334  -0.432  -0.391  -0.322  -0.419  -0.410
121   S         1.027   1.050   1.108   1.092   1.120   1.207   1.081   1.112   1.199
122   G         1.027   1.050   1.108   0.893   0.932   1.037   1.081   1.112   1.199
123   T         1.027   1.050   1.108   1.018   1.057   1.144   1.081   1.112   1.199
124   T         1.027   1.050   1.108   1.018   1.057   1.144   1.081   1.112   1.199
125   D         0.256   0.342  -0.038   0.279   0.386  -0.113   0.263   0.382  -0.221
126   A         1.027   1.050   1.108   0.993   1.015   1.123   1.081   1.112   1.199
127   E         1.027   1.050   1.108   1.104   1.130   1.218   1.081   1.112   1.199
128   G         1.027   1.050   1.108   0.893   0.932   1.037   1.081   1.112   1.199
129   K         1.027   1.050   1.108   0.952   0.989   1.088   1.081   1.112   1.199
130   N        -1.102  -1.100  -0.905  -1.243  -1.310  -1.009  -1.258  -1.252  -0.985
131   T        -0.124  -0.118  -0.142  -0.113  -0.096  -0.137  -0.322  -0.320  -0.402
132   R         1.027   1.050   1.108   1.095   1.121   1.210   1.081   1.112   1.199
133   G         1.027   1.050   1.108   0.893   0.932   1.037   1.081   1.112   1.199
134   Y         1.027   1.050   1.108   1.255   1.280   1.347   1.081   1.112   1.199
135   D         1.027   1.050   1.108   0.936   0.967   1.074   1.081   1.112   1.199
136   P         1.027   1.050   1.108   1.113   1.143   1.225   1.081   1.112   1.199
137   L        -0.816  -0.895  -0.882  -1.000  -1.121  -1.076  -0.907  -1.035  -0.959
138   N        -1.678  -1.574  -1.428  -1.587  -1.510  -1.213  -1.609  -1.487  -1.257
139   D         1.027   1.050   1.108   0.936   0.967   1.074   1.081   1.112   1.199
140   I         1.027   1.050   1.108   1.022   1.050   1.147   1.081   1.112   1.199
141   E        -0.816  -0.811  -0.874  -0.782  -0.863  -0.945  -0.907  -0.952  -0.949
142   W         1.027   1.050   1.108   1.309   1.332   1.394   1.081   1.112   1.199
143   L         1.027   1.050   1.108   0.837   0.883   0.989   1.081   1.112   1.199
144   Q        -0.479  -0.761  -0.843  -0.056  -0.435  -0.610  -0.439  -0.801  -0.907
145   D        -0.479  -0.761  -0.843  -0.399  -0.790  -0.937  -0.439  -0.801  -0.907
146   E         1.027   1.050   1.108   1.104   1.130   1.218   1.081   1.112   1.199
147   I         1.027   1.050   1.108   1.022   1.050   1.147   1.081   1.112   1.199
148   R        -1.544  -1.643  -1.420  -1.461  -1.598  -1.308  -1.492  -1.537  -1.248
149   L        -2.032  -1.926  -1.835  -2.075  -1.898  -1.705  -1.726  -1.608  -1.421
150   W         1.027   1.050   1.108   1.309   1.332   1.394   1.081   1.112   1.199
151   V         0.256   0.428  -0.037   0.331   0.542  -0.129   0.263   0.496  -0.219
152   E        -1.457  -1.600  -1.418  -1.475  -1.706  -1.498  -1.375  -1.488  -1.247
153   G        -0.124  -0.118  -0.142  -0.287  -0.275  -0.311  -0.322  -0.320  -0.402
154   N         1.027   1.050   1.108   1.123   1.143   1.234   1.081   1.112   1.199
155   L         1.027   1.050   1.108   0.837   0.883   0.989   1.081   1.112   1.199
156   K        -1.812  -1.868  -1.815  -1.443  -1.518  -1.369  -1.492  -1.541  -1.404
157   K        -0.328  -0.147  -0.118  -0.524  -0.190  -0.196  -0.673  -0.368  -0.359
158   R        -0.328  -0.339  -0.167  -0.532  -0.594  -0.320  -0.673  -0.706  -0.446
159   W         1.027   1.050   1.108   1.309   1.332   1.394   1.081   1.112   1.199
160   G         0.256   0.114  -0.060   0.234   0.067  -0.187   0.263   0.053  -0.259
161   S         0.256   0.114  -0.060   0.434   0.252  -0.027   0.263   0.053  -0.259
162   I        -0.124  -0.033  -0.102  -0.239  -0.093  -0.256  -0.322  -0.180  -0.332
163   V         0.256   0.094  -0.058   0.207  -0.006  -0.251   0.263   0.022  -0.256
164   R         1.027   1.050   1.108   1.095   1.121   1.210   1.081   1.112   1.199
165   K        -0.124   0.070  -0.088  -0.147   0.157  -0.144  -0.322  -0.015  -0.307
166   H         1.027   1.050   1.108   1.280   1.302   1.369   1.081   1.112   1.199
167   T        -0.328  -0.338  -0.167  -0.564  -0.597  -0.323  -0.673  -0.704  -0.446
168   A        -0.479  -0.400  -0.799  -0.352  -0.251  -0.844  -0.439  -0.334  -0.851
169   T         0.256   0.094  -0.058   0.327   0.114  -0.173   0.263   0.022  -0.256
170   K         1.027   1.050   1.108   0.952   0.989   1.088   1.081   1.112   1.199
171   S        -0.328  -0.337  -0.167  -0.514  -0.571  -0.296  -0.673  -0.702  -0.447
172   S        -1.457  -1.544  -1.409  -1.279  -1.416  -1.196  -1.375  -1.450  -1.240
173   I        -2.166  -2.067  -1.836  -2.209  -2.045  -1.721  -1.843  -1.727  -1.421
174   V        -0.124  -0.033  -0.102  -0.386  -0.232  -0.384  -0.322  -0.180  -0.332
175   D        -0.968  -1.030  -0.880  -1.108  -1.156  -0.903  -1.141  -1.180  -0.957
176   T         1.027   1.050   1.108   1.018   1.057   1.144   1.081   1.112   1.199
177   L         0.256   0.323  -0.041   0.205   0.305  -0.132   0.263   0.356  -0.226
178   Q        -0.124  -0.033  -0.102   0.030   0.167  -0.006  -0.322  -0.180  -0.332
179   A        -1.544  -1.558  -1.409  -1.419  -1.436  -1.205  -1.492  -1.467  -1.239
180   Q         1.027   1.050   1.108   1.233   1.259   1.329   1.081   1.112   1.199
181   F        -0.124  -0.033  -0.102  -0.106   0.043  -0.160  -0.322  -0.180  -0.332
182   G        -0.328  -0.339  -0.167  -0.637  -0.643  -0.353  -0.673  -0.706  -0.446
183   G         1.027   1.050   1.108   0.893   0.932   1.037   1.081   1.112   1.199
184   Y         1.027   1.050   1.108   1.255   1.280   1.347   1.081   1.112   1.199
185   G        -0.479  -0.354  -0.804  -0.453  -0.279  -0.929  -0.439  -0.276  -0.856
186   S        -0.124  -0.033  -0.102  -0.137   0.001  -0.157  -0.322  -0.180  -0.332
187   H        -1.678  -1.502  -1.423  -1.610  -1.404  -1.288  -1.609  -1.430  -1.252
188   A        -1.544  -1.481  -1.405  -1.641  -1.544  -1.380  -1.492  -1.410  -1.236
189   P        -2.032  -1.926  -1.835  -1.889  -1.779  -1.635  -1.726  -1.608  -1.421
190   M        -1.678  -1.605  -1.430  -1.722  -1.681  -1.419  -1.609  -1.511  -1.258
191   I        -0.968  -1.029  -0.875  -1.193  -1.270  -1.020  -1.141  -1.180  -0.952
192   Q        -1.678  -1.605  -1.430  -1.621  -1.557  -1.265  -1.609  -1.511  -1.258
193   K        -0.968  -0.888  -0.864  -1.109  -0.991  -0.946  -1.141  -1.036  -0.940
194   A        -1.171  -1.291  -1.386  -0.965  -1.196  -1.291  -1.024  -1.169  -1.215
195   L         0.256   0.293  -0.047   0.164   0.231  -0.246   0.263   0.314  -0.236
196   D         0.256   0.406  -0.039   0.245   0.434  -0.201   0.263   0.467  -0.223
197   R        -1.678  -1.688  -1.431  -1.827  -1.831  -1.457  -1.609  -1.580  -1.259
198   L        -0.124   0.004  -0.119  -0.376  -0.163  -0.369  -0.322  -0.120  -0.362
199   K        -2.387  -2.329  -2.170  -2.051  -1.993  -1.811  -1.843  -1.778  -1.532
200   G        -0.930  -0.945  -0.889  -1.235  -1.308  -1.184  -1.057  -1.096  -0.967
201   L        -0.479  -0.761  -0.843  -0.527  -0.916  -1.076  -0.439  -0.801  -0.907
202   P        -1.171  -1.359  -1.390  -0.865  -1.148  -1.252  -1.024  -1.234  -1.218
203   P         1.027   1.050   1.108   1.113   1.143   1.225   1.081   1.112   1.199
204   L         0.256   0.293  -0.047   0.205   0.271  -0.140   0.263   0.314  -0.236
205   E        -0.124  -0.033  -0.102  -0.049   0.083  -0.042  -0.322  -0.180  -0.332
206   K        -1.678  -1.551  -1.421  -1.771  -1.597  -1.337  -1.609  -1.474  -1.250
207   W         1.027   1.050   1.108   1.309   1.332   1.394   1.081   1.112   1.199
208   D         0.256   0.094  -0.058   0.274   0.069  -0.158   0.263   0.022  -0.256
209   D        -0.816  -0.842  -0.849  -0.851  -0.864  -0.870  -0.907  -0.909  -0.918
210   E        -0.124  -0.179  -0.147  -0.144  -0.257  -0.268  -0.322  -0.422  -0.411
211   W        -1.544  -1.404  -1.393  -1.342  -1.169  -1.138  -1.492  -1.312  -1.223
212   I        -0.479  -0.581  -0.812  -0.367  -0.522  -0.944  -0.439  -0.576  -0.867
213   T        -2.032  -2.038  -1.830  -1.962  -1.973  -1.690  -1.726  -1.699  -1.417
214   R        -1.102  -1.030  -0.898  -1.254  -1.141  -0.939  -1.258  -1.158  -0.977
215   V         1.027   1.050   1.108   0.889   0.922   1.034   1.081   1.112   1.199
216   V         1.027   1.050   1.108   0.889   0.922   1.034   1.081   1.112   1.199
217   K        -1.189  -1.142  -0.909  -1.373  -1.273  -0.927  -1.375  -1.301  -0.991
218   S        -0.968  -1.029  -0.876  -1.054  -1.137  -0.888  -1.141  -1.179  -0.952
219   F         1.027   1.050   1.108   1.175   1.200   1.279   1.081   1.112   1.199
220   M        -0.816  -0.978  -0.882  -0.598  -0.888  -0.832  -0.907  -1.103  -0.959
221   M        -2.166  -2.001  -1.836  -1.899  -1.730  -1.465  -1.843  -1.660  -1.421
222   E        -0.816  -0.865  -0.856  -0.796  -0.850  -0.901  -0.907  -0.942  -0.924
223   K         1.027   1.050   1.108   0.952   0.989   1.088   1.081   1.112   1.199
224   F         1.027   1.050   1.108   1.175   1.200   1.279   1.081   1.112   1.199
225   P         1.027   1.050   1.108   1.113   1.143   1.225   1.081   1.112   1.199
226   T         1.027   1.050   1.108   1.018   1.057   1.144   1.081   1.112   1.199
227   V         1.027   1.050   1.108   0.889   0.922   1.034   1.081   1.112   1.199
228   L        -0.124  -0.261  -0.155  -0.376  -0.600  -0.427  -0.322  -0.565  -0.426
229   A        -0.124  -0.033  -0.102  -0.201  -0.070  -0.188  -0.322  -0.180  -0.332
230   L         1.027   1.050   1.108   0.837   0.883   0.989   1.081   1.112   1.199
231   N         1.027   1.050   1.108   1.123   1.143   1.234   1.081   1.112   1.199
232   K         1.027   1.050   1.108   0.952   0.989   1.088   1.081   1.112   1.199
233   I        -0.392  -0.332  -0.165  -0.495  -0.415  -0.158  -0.790  -0.692  -0.443
234   D         1.027   1.050   1.108   0.936   0.967   1.074   1.081   1.112   1.199
235   H         1.027   1.050   1.108   1.280   1.302   1.369   1.081   1.112   1.199
236   P         1.027   1.050   1.108   1.113   1.143   1.225   1.081   1.112   1.199
237   D         1.027   1.050   1.108   0.936   0.967   1.074   1.081   1.112   1.199
238   A         0.256   0.342  -0.038   0.331   0.432  -0.079   0.263   0.382  -0.221
239   D         1.027   1.050   1.108   0.936   0.967   1.074   1.081   1.112   1.199
240   K        -0.479  -0.590  -0.822  -0.342  -0.491  -0.797  -0.439  -0.584  -0.880
241   N         1.027   1.050   1.108   1.123   1.143   1.234   1.081   1.112   1.199
242   V        -0.124  -0.261  -0.155  -0.325  -0.565  -0.390  -0.322  -0.565  -0.426
243   S         0.256   0.094  -0.058   0.415   0.196  -0.074   0.263   0.022  -0.256
244   K         1.027   1.050   1.108   0.952   0.989   1.088   1.081   1.112   1.199
245   I         1.027   1.050   1.108   1.022   1.050   1.147   1.081   1.112   1.199
246   M        -1.102  -1.100  -0.905  -1.045  -1.110  -0.844  -1.258  -1.252  -0.985
247   L        -0.816  -0.978  -0.882  -1.015  -1.239  -1.072  -0.907  -1.103  -0.959
248   K        -0.479  -0.608  -0.822  -0.325  -0.474  -0.758  -0.439  -0.609  -0.880
249   Y        -1.171  -1.396  -1.402  -0.634  -0.952  -0.997  -1.024  -1.270  -1.230
250   P        -0.124  -0.261  -0.155  -0.135  -0.407  -0.281  -0.322  -0.565  -0.426
251   D        -1.678  -1.575  -1.427  -1.766  -1.591  -1.375  -1.609  -1.486  -1.256
252   T        -2.166  -1.986  -1.836  -2.231  -1.909  -1.745  -1.843  -1.651  -1.422
253   K        -1.171  -1.396  -1.402  -0.986  -1.296  -1.299  -1.024  -1.270  -1.230
254   A        -2.032  -2.056  -1.831  -1.926  -2.007  -1.627  -1.726  -1.715  -1.418
255   V         1.027   1.050   1.108   0.889   0.922   1.034   1.081   1.112   1.199
256   L         1.027   1.050   1.108   0.837   0.883   0.989   1.081   1.112   1.199
257   T        -0.479  -0.761  -0.843  -0.278  -0.643  -0.782  -0.439  -0.801  -0.907
258   S         1.027   1.050   1.108   1.092   1.120   1.207   1.081   1.112   1.199
259   A        -0.124  -0.033  -0.102  -0.201  -0.070  -0.188  -0.322  -0.180  -0.332
260   V         0.256   0.428  -0.037   0.331   0.542  -0.129   0.263   0.496  -0.219
261   T        -0.328  -0.339  -0.167  -0.527  -0.550  -0.277  -0.673  -0.706  -0.446
262   E         1.027   1.050   1.108   1.104   1.130   1.218   1.081   1.112   1.199
263   V         0.256   0.094  -0.058   0.217   0.008  -0.223   0.263   0.022  -0.256
264   F         1.027   1.050   1.108   1.175   1.200   1.279   1.081   1.112   1.199
265   L         0.256   0.293  -0.047   0.164   0.231  -0.246   0.263   0.314  -0.236
266   R         1.027   1.050   1.108   1.095   1.121   1.210   1.081   1.112   1.199
267   K         0.256   0.114  -0.060   0.291   0.119  -0.147   0.263   0.053  -0.259
268   L         0.256   0.094  -0.058   0.205   0.031  -0.156   0.263   0.022  -0.256
269   K        -0.328  -0.147  -0.118  -0.623  -0.300  -0.280  -0.673  -0.368  -0.359
270   K        -0.479  -0.354  -0.804  -0.371  -0.204  -0.834  -0.439  -0.276  -0.856
271   Q         1.027   1.050   1.108   1.233   1.259   1.329   1.081   1.112   1.199
272   G        -0.479  -0.354  -0.804  -0.389  -0.223  -0.787  -0.439  -0.276  -0.856
273   F        -0.392  -0.334  -0.166  -0.413  -0.317  -0.079  -0.790  -0.696  -0.444
274   I        -0.124  -0.179  -0.147  -0.239  -0.351  -0.353  -0.322  -0.422  -0.411
275   L        -1.457  -1.141  -1.381  -1.412  -0.970  -1.305  -1.375  -1.018  -1.211
276   Y         1.027   1.050   1.108   1.255   1.280   1.347   1.081   1.112   1.199
277   E        -0.968  -1.005  -0.869  -1.095  -1.104  -0.919  -1.141  -1.139  -0.944
278   E        -0.816  -0.632  -0.843  -0.755  -0.473  -0.855  -0.907  -0.653  -0.911
279   G         1.027   1.050   1.108   0.893   0.932   1.037   1.081   1.112   1.199
280   T        -0.124  -0.261  -0.155  -0.177  -0.409  -0.262  -0.322  -0.565  -0.426
281   E         1.027   1.050   1.108   1.104   1.130   1.218   1.081   1.112   1.199
282   F         1.027   1.050   1.108   1.175   1.200   1.279   1.081   1.112   1.199
283   V        -0.479  -0.400  -0.799  -0.478  -0.366  -0.972  -0.439  -0.334  -0.851
284   D         1.027   1.050   1.108   0.936   0.967   1.074   1.081   1.112   1.199
285   T         1.027   1.050   1.108   1.018   1.057   1.144   1.081   1.112   1.199
286   F        -2.521  -2.465  -2.184  -2.263  -2.246  -1.815  -1.959  -1.876  -1.541
287   E        -0.328  -0.306  -0.164  -0.533  -0.517  -0.310  -0.673  -0.645  -0.441
288   D         1.027   1.050   1.108   0.936   0.967   1.074   1.081   1.112   1.199
289   -         0.003  -0.048  -0.099  -0.130  -0.188  -0.255  -0.116  -0.203  -0.327
290   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
291   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
292   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
293   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
294   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
295   -         0.003   0.133  -0.079   0.078   0.269  -0.119  -0.116   0.081  -0.291
296   E        -0.124   0.029  -0.114  -0.252  -0.022  -0.246  -0.322  -0.080  -0.353
297   P        -2.032  -1.999  -1.824  -1.917  -1.903  -1.675  -1.726  -1.672  -1.413
298   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
299   K        -2.032  -1.710  -1.811  -2.121  -1.635  -1.772  -1.726  -1.399  -1.402
300   L         1.027   1.050   1.108   0.837   0.883   0.989   1.081   1.112   1.199
301   K         1.027   1.050   1.108   0.952   0.989   1.088   1.081   1.112   1.199
302   P         0.256   0.094  -0.058   0.452   0.245  -0.015   0.263   0.022  -0.256
303   L         1.027   1.050   1.108   0.837   0.883   0.989   1.081   1.112   1.199
304   D         0.256   0.114  -0.060   0.274   0.096  -0.161   0.263   0.053  -0.259
305   D        -0.392  -0.330  -0.164  -0.692  -0.575  -0.311  -0.790  -0.689  -0.442
306   K         0.256   0.114  -0.060   0.295   0.123  -0.136   0.263   0.053  -0.259
307   I        -1.171  -1.042  -1.355  -1.113  -0.949  -1.341  -1.024  -0.894  -1.183
308   L        -1.678  -1.492  -1.413  -1.846  -1.548  -1.439  -1.609  -1.411  -1.243
309   N        -1.812  -1.675  -1.797  -1.433  -1.284  -1.468  -1.492  -1.354  -1.389
310   R         1.027   1.050   1.108   1.095   1.121   1.210   1.081   1.112   1.199
311   I         0.256   0.293  -0.047   0.331   0.380  -0.148   0.263   0.314  -0.236
312   E        -0.479  -0.546  -0.811  -0.251  -0.356  -0.804  -0.439  -0.531  -0.866
313   N        -0.479  -0.489  -0.813  -0.249  -0.289  -0.831  -0.439  -0.465  -0.868
314   I        -0.816  -0.895  -0.882  -0.920  -1.120  -1.103  -0.907  -1.035  -0.959
315   R        -0.479  -0.761  -0.843  -0.217  -0.605  -0.767  -0.439  -0.801  -0.907
316   D         1.027   1.050   1.108   0.936   0.967   1.074   1.081   1.112   1.199
317   L        -0.124  -0.261  -0.155  -0.285  -0.462  -0.274  -0.322  -0.565  -0.426
318   V         1.027   1.050   1.108   0.889   0.922   1.034   1.081   1.112   1.199
319   L         1.027   1.050   1.108   0.837   0.883   0.989   1.081   1.112   1.199
320   Y         0.256   0.114  -0.060   0.603   0.422   0.119   0.263   0.053  -0.259
321   R         1.027   1.050   1.108   1.095   1.121   1.210   1.081   1.112   1.199
322   F         0.256   0.114  -0.060   0.539   0.365   0.098   0.263   0.053  -0.259
323   G         1.027   1.050   1.108   0.893   0.932   1.037   1.081   1.112   1.199
324   S         1.027   1.050   1.108   1.092   1.120   1.207   1.081   1.112   1.199
325   T         1.027   1.050   1.108   1.018   1.057   1.144   1.081   1.112   1.199
326   G         1.027   1.050   1.108   0.893   0.932   1.037   1.081   1.112   1.199
327   V         0.256   0.293  -0.047   0.190   0.246  -0.275   0.263   0.314  -0.236
328   V        -0.479  -0.761  -0.843  -0.383  -0.739  -0.818  -0.439  -0.801  -0.907
329   Q         0.256   0.114  -0.060   0.574   0.390   0.083   0.263   0.053  -0.259
330   V        -0.816  -0.719  -0.845  -1.024  -0.857  -1.059  -0.907  -0.767  -0.910
331   L         1.027   1.050   1.108   0.837   0.883   0.989   1.081   1.112   1.199
332   Q        -0.479  -0.761  -0.843  -0.098  -0.503  -0.711  -0.439  -0.801  -0.907
333   A        -0.124  -0.261  -0.155  -0.246  -0.512  -0.357  -0.322  -0.565  -0.426
334   A         1.027   1.050   1.108   0.993   1.015   1.123   1.081   1.112   1.199
335   T        -0.816  -0.767  -0.834  -0.801  -0.682  -0.782  -0.907  -0.809  -0.896
336   D        -1.457  -1.398  -1.411  -1.423  -1.370  -1.308  -1.375  -1.332  -1.241
337   I        -1.678  -1.516  -1.415  -1.941  -1.698  -1.537  -1.609  -1.435  -1.246
338   L         1.027   1.050   1.108   0.837   0.883   0.989   1.081   1.112   1.199
339   G        -1.544  -1.386  -1.385  -1.610  -1.397  -1.346  -1.492  -1.326  -1.218
340   L         1.027   1.050   1.108   0.837   0.883   0.989   1.081   1.112   1.199
341   I        -0.328  -0.318  -0.165  -0.631  -0.641  -0.396  -0.673  -0.668  -0.443
342   P         1.027   1.050   1.108   1.113   1.143   1.225   1.081   1.112   1.199
343   V         1.027   1.050   1.108   0.889   0.922   1.034   1.081   1.112   1.199
344   Y        -0.328  -0.337  -0.167  -0.278  -0.324  -0.084  -0.673  -0.702  -0.447
345   T        -0.328  -0.147  -0.118  -0.483  -0.153  -0.160  -0.673  -0.368  -0.359
346   V         1.027   1.050   1.108   0.889   0.922   1.034   1.081   1.112   1.199
347   K        -0.392  -0.340  -0.167  -0.687  -0.595  -0.317  -0.790  -0.707  -0.446
348   N         0.256   0.342  -0.038   0.461   0.559   0.024   0.263   0.382  -0.221
349   I        -1.171  -1.291  -1.386  -0.937  -1.162  -1.271  -1.024  -1.169  -1.215
350   Q        -1.457  -1.320  -1.388  -1.125  -0.973  -1.072  -1.375  -1.232  -1.220
351   T        -0.392  -0.336  -0.165  -0.619  -0.521  -0.253  -0.790  -0.700  -0.443
352   F         1.027   1.050   1.108   1.175   1.200   1.279   1.081   1.112   1.199
353   T        -1.457  -1.394  -1.392  -1.452  -1.370  -1.377  -1.375  -1.299  -1.223
354   G        -0.479  -0.761  -0.843  -0.413  -0.782  -0.897  -0.439  -0.801  -0.907
355   G        -1.457  -1.410  -1.400  -1.490  -1.429  -1.363  -1.375  -1.320  -1.231
356   N        -1.588  -1.689  -1.435  -1.491  -1.651  -1.291  -1.516  -1.579  -1.262
357   G        -0.198  -0.306  -0.164  -0.406  -0.585  -0.341  -0.446  -0.645  -0.440
358   T        -0.930  -0.718  -0.833  -0.947  -0.595  -0.829  -1.057  -0.757  -0.895
359   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
360   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
361   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
362   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
363   N        -2.032  -2.106  -1.846  -1.741  -1.884  -1.520  -1.726  -1.747  -1.428
364   V         1.027   1.050   1.108   0.889   0.922   1.034   1.081   1.112   1.199
365   F         1.027   1.050   1.108   1.175   1.200   1.279   1.081   1.112   1.199
366   R         1.027   1.050   1.108   1.095   1.121   1.210   1.081   1.112   1.199
367   D         1.027   1.050   1.108   0.936   0.967   1.074   1.081   1.112   1.199
368   C         1.027   1.050   1.108   1.287   1.308   1.375   1.081   1.112   1.199
369   F        -2.032  -2.031  -1.831  -1.961  -2.006  -1.754  -1.726  -1.693  -1.418
370   L         1.027   1.050   1.108   0.837   0.883   0.989   1.081   1.112   1.199
371   V         1.027   1.050   1.108   0.889   0.922   1.034   1.081   1.112   1.199
372   K         0.256   0.293  -0.047   0.291   0.348  -0.125   0.263   0.314  -0.236
373   R        -0.968  -0.980  -0.866  -1.077  -1.038  -0.848  -1.141  -1.107  -0.940
374   G         0.256   0.094  -0.058   0.236   0.039  -0.180   0.263   0.022  -0.256
375   T        -0.124  -0.190  -0.145  -0.177  -0.283  -0.244  -0.322  -0.441  -0.407
376   P        -0.968  -0.809  -0.855  -1.042  -0.782  -0.833  -1.141  -0.913  -0.926
377   V         0.256   0.114  -0.060   0.213   0.029  -0.238   0.263   0.053  -0.259
378   G        -1.457  -1.393  -1.404  -1.555  -1.486  -1.452  -1.375  -1.311  -1.234
379   K        -2.032  -2.096  -1.839  -1.956  -2.020  -1.650  -1.726  -1.741  -1.424
380   V         1.027   1.050   1.108   0.889   0.922   1.034   1.081   1.112   1.199
381   A        -0.479  -0.590  -0.822  -0.353  -0.509  -0.885  -0.439  -0.584  -0.880
382   R        -0.479  -0.489  -0.813  -0.207  -0.222  -0.693  -0.439  -0.465  -0.868
383   Y        -0.968  -0.949  -0.865  -0.966  -0.896  -0.747  -1.141  -1.062  -0.936
384   I         0.256   0.114  -0.060   0.331   0.137  -0.173   0.263   0.053  -0.259
385   M        -0.124  -0.118  -0.142   0.005   0.000  -0.171  -0.322  -0.320  -0.402
386   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
387   G         1.027   1.050   1.108   0.893   0.932   1.037   1.081   1.112   1.199
388   E        -0.479  -0.469  -0.809  -0.407  -0.422  -0.900  -0.439  -0.443  -0.864
389   V        -1.171  -1.396  -1.402  -1.123  -1.452  -1.490  -1.024  -1.270  -1.230
390   T        -0.816  -0.978  -0.882  -0.799  -1.038  -0.910  -0.907  -1.103  -0.959
391   I        -0.816  -0.779  -0.841  -0.823  -0.705  -0.829  -0.907  -0.825  -0.905
392   A        -0.479  -0.590  -0.822  -0.331  -0.485  -0.836  -0.439  -0.584  -0.880
393   S        -1.171  -1.294  -1.386  -0.932  -1.120  -1.225  -1.024  -1.172  -1.214
394   I        -0.328  -0.338  -0.167  -0.631  -0.692  -0.406  -0.673  -0.704  -0.446
395   E         1.027   1.050   1.108   1.100   1.123   1.215   1.081   1.112   1.199
396   T        -0.328  -0.147  -0.118  -0.677  -0.354  -0.325  -0.673  -0.368  -0.359
397   V         0.256   0.094  -0.058   0.213   0.000  -0.235   0.263   0.022  -0.256
398   G         0.256   0.114  -0.060   0.236   0.067  -0.182   0.263   0.053  -0.259
399   G         0.256   0.432  -0.037   0.231   0.448  -0.157   0.263   0.501  -0.219
400   V        -1.029  -0.963  -0.875  -1.297  -1.160  -1.010  -1.210  -1.102  -0.950
401   R        -0.479  -0.563  -0.814  -0.236  -0.352  -0.761  -0.439  -0.551  -0.870
402   V        -0.124  -0.033  -0.102  -0.325  -0.182  -0.299  -0.322  -0.180  -0.332
403   S        -0.968  -1.041  -0.873  -1.136  -1.245  -0.984  -1.141  -1.191  -0.949
404   E         1.027   1.050   1.108   1.104   1.130   1.218   1.081   1.112   1.199
405   E        -0.968  -1.029  -0.871  -1.080  -1.158  -0.909  -1.141  -1.179  -0.948
406   S        -1.171  -1.042  -1.355  -0.993  -0.831  -1.232  -1.024  -0.894  -1.183
407   L        -2.387  -2.268  -2.168  -2.271  -2.130  -2.035  -1.843  -1.732  -1.531
408   V        -0.124  -0.166  -0.149  -0.325  -0.398  -0.380  -0.322  -0.400  -0.414
409   E        -1.812  -1.793  -1.812  -1.734  -1.752  -1.801  -1.492  -1.478  -1.402
410   P        -2.032  -1.872  -1.822  -1.939  -1.754  -1.654  -1.726  -1.571  -1.411
411   G         1.027   1.050   1.108   0.893   0.932   1.037   1.081   1.112   1.199
412   K         0.256   0.406  -0.039   0.261   0.455  -0.190   0.263   0.467  -0.223
413   N         0.256   0.114  -0.060   0.450   0.257  -0.043   0.263   0.053  -0.259
414   D         1.027   1.050   1.108   0.936   0.967   1.074   1.081   1.112   1.199
415   I         1.027   1.050   1.108   1.022   1.050   1.147   1.081   1.112   1.199
416   L         1.027   1.050   1.108   0.837   0.883   0.989   1.081   1.112   1.199
417   G        -2.032  -1.896  -1.821  -1.800  -1.556  -1.479  -1.726  -1.569  -1.409
418   F         1.027   1.050   1.108   1.175   1.200   1.279   1.081   1.112   1.199
419   K        -0.124  -0.261  -0.155  -0.239  -0.468  -0.305  -0.322  -0.565  -0.426
420   I        -0.816  -0.952  -0.874  -0.920  -1.145  -1.085  -0.907  -1.062  -0.949
421   A        -1.678  -1.688  -1.431  -1.912  -1.918  -1.516  -1.609  -1.580  -1.259
422   P         0.187  -0.044  -0.098   0.337  -0.006  -0.153   0.165  -0.196  -0.324
423   R        -1.741  -1.721  -1.435  -1.950  -1.911  -1.475  -1.668  -1.609  -1.263
424   S        -0.603  -0.819  -0.867  -0.396  -0.718  -0.835  -0.599  -0.887  -0.938
425   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
426   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
427   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
428   A        -1.044  -0.861  -0.865  -1.196  -0.927  -0.928  -1.206  -0.965  -0.936
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P42942
Output conservation file - output/P42942
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
