1     M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
2     M         2.251   2.280   2.398   2.575   2.620   2.826   2.595   2.643   2.863
3     S        -0.129  -0.232  -0.292   0.070  -0.085  -0.155  -0.119  -0.257  -0.331
4     D         0.842   0.866   0.958   0.631   0.674   0.804   0.424   0.457   0.581
5     L         1.405   1.434   1.290   1.276   1.316   1.127   1.509   1.555   1.269
6     T         2.251   2.280   2.398   2.375   2.413   2.620   2.595   2.643   2.863
7     P         0.608   0.532   0.404   1.021   0.896   0.671   0.605   0.483   0.272
8     I         0.608   0.585   0.427   0.491   0.451   0.219   0.605   0.560   0.308
9     F         2.251   2.280   2.398   2.498   2.549   2.747   2.595   2.643   2.863
10    R        -0.383  -0.464  -0.400  -0.335  -0.455  -0.365  -0.481  -0.565  -0.484
11    K        -0.383  -0.458  -0.399  -0.485  -0.566  -0.485  -0.481  -0.557  -0.480
12    Y         0.025   0.025   0.110   0.027  -0.031   0.108  -0.300  -0.304  -0.197
13    V         0.608   0.532   0.404   0.877   0.748   0.548   0.605   0.483   0.272
14    A        -0.968  -0.978  -0.915  -0.904  -0.909  -0.821  -0.853  -0.859  -0.774
15    V         0.165   0.117   0.186   0.182   0.138   0.241  -0.114  -0.174  -0.089
16    I         0.165   0.107   0.171   0.111   0.031   0.122  -0.114  -0.190  -0.108
17    D         0.165   0.224   0.207   0.086   0.174   0.154  -0.114  -0.035  -0.053
18    D         1.091   1.102   1.081   1.025   1.035   0.952   0.933   0.942   0.845
19    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    E         0.291   0.189   0.213   0.214   0.066   0.105   0.112  -0.051  -0.035
23    Q        -0.497  -0.486  -0.440  -0.699  -0.695  -0.632  -0.597  -0.585  -0.521
24    N        -1.069  -1.037  -0.974  -1.221  -1.176  -1.085  -0.951  -0.915  -0.832
25    G         1.219   1.186   1.155   1.506   1.449   1.374   1.176   1.106   0.998
26    I         0.075   0.068   0.151  -0.408  -0.431  -0.321  -0.242  -0.248  -0.140
27    D         1.091   1.184   1.103   1.050   1.197   1.027   0.933   1.101   0.891
28    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    E         0.106   0.071   0.132  -0.302  -0.398  -0.312  -0.176  -0.235  -0.162
32    R         0.106   0.097   0.150   0.148   0.116   0.186  -0.176  -0.197  -0.134
33    K         0.165   0.217   0.221  -0.059   0.043   0.025  -0.114  -0.032  -0.039
34    Q        -0.968  -0.975  -0.915  -0.974  -0.958  -0.898  -0.853  -0.857  -0.774
35    E        -0.312  -0.373  -0.400  -0.336  -0.411  -0.467  -0.360  -0.443  -0.471
36    D        -0.968  -0.899  -0.902  -0.949  -0.839  -0.856  -0.853  -0.775  -0.760
37    F        -1.445  -1.413  -1.356  -1.311  -1.262  -1.178  -1.099  -1.065  -0.986
38    G        -0.968  -0.944  -0.913  -0.779  -0.722  -0.685  -0.853  -0.827  -0.772
39    N        -0.968  -0.975  -0.915  -0.846  -0.837  -0.755  -0.853  -0.857  -0.774
40    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
45    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
46    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
47    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
48    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
49    S        -0.968  -0.942  -0.913  -1.211  -1.154  -1.160  -0.853  -0.825  -0.772
50    N        -0.968  -0.992  -0.947  -1.113  -1.153  -1.123  -0.853  -0.873  -0.806
51    E        -0.492  -0.453  -0.440  -0.470  -0.371  -0.358  -0.607  -0.556  -0.526
52    T        -0.492  -0.405  -0.434  -0.341  -0.209  -0.261  -0.607  -0.509  -0.520
53    C        -1.445  -1.413  -1.356  -1.108  -1.084  -0.969  -1.099  -1.065  -0.986
54    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    F        -1.354  -1.319  -1.292  -1.149  -1.087  -1.054  -1.024  -0.986  -0.932
57    R        -0.383  -0.383  -0.362  -0.388  -0.383  -0.343  -0.481  -0.466  -0.430
58    D         1.405   1.359   1.287   1.628   1.578   1.501   1.509   1.424   1.263
59    S        -0.383  -0.440  -0.398  -0.458  -0.553  -0.489  -0.481  -0.531  -0.476
60    F         2.251   2.280   2.398   2.498   2.549   2.747   2.595   2.643   2.863
61    I        -0.383  -0.414  -0.390  -0.529  -0.582  -0.566  -0.481  -0.515  -0.473
62    K         2.251   2.280   2.398   2.304   2.354   2.546   2.595   2.643   2.863
63    E         2.251   2.280   2.398   2.190   2.237   2.429   2.595   2.643   2.863
64    C        -0.383  -0.380  -0.396  -0.099  -0.141  -0.143  -0.481  -0.486  -0.478
65    A        -1.762  -1.736  -1.679  -1.453  -1.407  -1.324  -1.205  -1.177  -1.096
66    R        -0.946  -0.914  -0.889  -0.961  -0.922  -0.871  -0.843  -0.808  -0.755
67    L        -0.383  -0.461  -0.419  -0.557  -0.657  -0.580  -0.481  -0.561  -0.502
68    L        -1.762  -1.736  -1.679  -1.434  -1.403  -1.304  -1.205  -1.177  -1.096
69    K         0.280   0.254   0.236   0.222   0.150   0.161   0.062  -0.001  -0.015
70    F        -0.383  -0.380  -0.396  -0.354  -0.410  -0.375  -0.481  -0.486  -0.478
71    L         0.280   0.191   0.221  -0.007  -0.125  -0.083   0.062  -0.067  -0.040
72    V        -1.354  -1.347  -1.329  -1.065  -1.083  -1.011  -1.024  -1.012  -0.964
73    E        -0.129  -0.156  -0.289  -0.158  -0.207  -0.432  -0.119  -0.157  -0.328
74    L         1.405   1.434   1.290   1.286   1.329   1.144   1.509   1.555   1.269
75    N        -0.383  -0.424  -0.399  -0.417  -0.463  -0.440  -0.481  -0.529  -0.483
76    K        -0.791  -0.789  -0.812  -0.721  -0.728  -0.786  -0.662  -0.658  -0.665
77    V         0.180   0.135   0.197   0.172   0.108   0.194  -0.119  -0.165  -0.081
78    I         0.842   0.850   0.948   0.442   0.436   0.561   0.424   0.423   0.558
79    K        -0.537  -0.538  -0.461  -0.640  -0.627  -0.508  -0.662  -0.652  -0.552
80    Q        -0.537  -0.476  -0.467  -0.868  -0.751  -0.759  -0.662  -0.596  -0.561
81    I        -0.537  -0.507  -0.454  -0.766  -0.739  -0.650  -0.662  -0.625  -0.549
82    E        -0.946  -0.860  -0.914  -0.859  -0.743  -0.792  -0.843  -0.756  -0.777
83    K        -0.946  -0.910  -0.909  -0.908  -0.845  -0.860  -0.843  -0.805  -0.772
84    N        -1.354  -1.308  -1.296  -1.194  -1.130  -1.101  -1.024  -0.977  -0.936
85    Y         2.251   2.280   2.398   2.593   2.643   2.845   2.595   2.643   2.863
86    L         0.608   0.708   0.453   0.494   0.627   0.266   0.605   0.755   0.350
87    D        -0.129   0.024  -0.218   0.002   0.225  -0.135  -0.119   0.087  -0.233
88    D        -0.946  -0.991  -0.935  -0.849  -0.909  -0.817  -0.843  -0.875  -0.797
89    F        -1.354  -1.380  -1.332  -1.106  -1.161  -1.090  -1.024  -1.039  -0.966
90    -         0.106   0.076   0.136  -0.026  -0.095  -0.009  -0.176  -0.226  -0.156
91    -        -0.608  -0.587  -0.507  -0.869  -0.829  -0.722  -0.730  -0.701  -0.601
92    -        -0.608  -0.587  -0.507  -0.800  -0.771  -0.651  -0.730  -0.701  -0.601
93    -         0.106   0.134   0.183  -0.128  -0.089  -0.034  -0.176  -0.137  -0.082
94    -        -0.608  -0.587  -0.507  -0.730  -0.694  -0.579  -0.730  -0.701  -0.601
95    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
96    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
97    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
98    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
99    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
100   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
101   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
102   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
103   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
104   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
105   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
106   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
107   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
108   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
109   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
110   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
111   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
112   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
113   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
114   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
115   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
116   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
117   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
118   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
119   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
120   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
121   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
122   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
123   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
124   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
125   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
126   N        -0.946  -0.883  -0.899  -0.791  -0.668  -0.716  -0.843  -0.774  -0.764
127   M         0.280   0.284   0.235   0.352   0.320   0.231   0.062   0.054  -0.019
128   S         1.017   1.085   1.058   0.945   1.055   0.974   0.786   0.910   0.796
129   D         0.280   0.388   0.298   0.225   0.404   0.245   0.062   0.217   0.091
130   A        -0.946  -0.991  -0.935  -0.908  -0.990  -0.907  -0.843  -0.875  -0.797
131   E         0.180   0.160   0.202  -0.108  -0.119  -0.066  -0.119  -0.134  -0.073
132   K         1.017   0.953   1.013   0.932   0.810   0.893   0.786   0.641   0.700
133   D         0.280   0.234   0.251   0.219   0.154   0.147   0.062   0.007   0.016
134   E        -0.383  -0.296  -0.359  -0.583  -0.448  -0.537  -0.481  -0.373  -0.428
135   F         0.180   0.160   0.202   0.175   0.165   0.229  -0.119  -0.134  -0.073
136   D         2.251   2.280   2.398   2.378   2.426   2.622   2.595   2.643   2.863
137   M        -0.946  -0.930  -0.905  -0.841  -0.824  -0.732  -0.843  -0.821  -0.768
138   E         1.405   1.316   1.271   1.397   1.279   1.208   1.509   1.348   1.233
139   C        -1.354  -1.319  -1.292  -1.138  -1.111  -1.047  -1.024  -0.986  -0.932
140   R        -0.383  -0.290  -0.358  -0.447  -0.293  -0.413  -0.481  -0.353  -0.426
141   L        -0.383  -0.461  -0.419  -0.523  -0.633  -0.553  -0.481  -0.561  -0.502
142   Q        -0.383  -0.461  -0.419  -0.525  -0.633  -0.566  -0.481  -0.561  -0.502
143   I         0.025   0.056   0.118  -0.349  -0.298  -0.206  -0.300  -0.257  -0.184
144   Q         1.405   1.316   1.271   1.451   1.339   1.274   1.509   1.348   1.233
145   Q        -0.129  -0.187  -0.285  -0.126  -0.207  -0.400  -0.119  -0.201  -0.322
146   Y         0.180   0.221   0.215   0.047   0.069   0.100  -0.119  -0.062  -0.055
147   F        -0.946  -0.962  -0.924  -0.658  -0.692  -0.628  -0.843  -0.852  -0.786
148   K        -0.383  -0.464  -0.400  -0.508  -0.627  -0.536  -0.481  -0.565  -0.484
149   K         1.017   0.992   1.020   0.932   0.882   0.907   0.786   0.722   0.715
150   F        -0.383  -0.356  -0.396  -0.547  -0.500  -0.517  -0.481  -0.461  -0.478
151   E        -0.383  -0.346  -0.382  -0.459  -0.408  -0.468  -0.481  -0.450  -0.462
152   F        -0.946  -0.879  -0.899  -0.798  -0.718  -0.743  -0.843  -0.771  -0.764
153   L         2.251   2.280   2.398   2.057   2.100   2.292   2.595   2.643   2.863
154   E         1.405   1.463   1.303   1.374   1.460   1.222   1.509   1.604   1.296
155   N        -1.354  -1.347  -1.329  -1.339  -1.329  -1.330  -1.024  -1.012  -0.964
156   Y         0.608   0.467   0.381   1.097   0.899   0.790   0.605   0.385   0.234
157   E         1.405   1.359   1.287   1.398   1.337   1.237   1.509   1.424   1.263
158   M        -1.354  -1.297  -1.295  -1.327  -1.260  -1.237  -1.024  -0.965  -0.935
159   E        -1.354  -1.347  -1.329  -1.454  -1.481  -1.449  -1.024  -1.012  -0.964
160   R         1.405   1.359   1.287   1.620   1.545   1.439   1.509   1.424   1.263
161   H        -0.129  -0.051  -0.239  -0.015   0.088  -0.167  -0.119  -0.018  -0.262
162   N        -0.312  -0.189  -0.352  -0.385  -0.180  -0.491  -0.360  -0.197  -0.410
163   L        -0.312  -0.376  -0.384  -0.417  -0.532  -0.499  -0.360  -0.446  -0.450
164   S        -0.608  -0.566  -0.507  -0.803  -0.749  -0.654  -0.730  -0.678  -0.601
165   L        -0.608  -0.566  -0.507  -0.912  -0.836  -0.767  -0.730  -0.678  -0.601
166   K         0.106   0.093   0.150  -0.209  -0.240  -0.161  -0.176  -0.207  -0.134
167   R        -0.608  -0.566  -0.507  -0.959  -0.931  -0.815  -0.730  -0.678  -0.601
168   F        -0.537  -0.545  -0.456  -0.723  -0.725  -0.595  -0.662  -0.660  -0.550
169   Q        -0.946  -0.921  -0.904  -0.882  -0.869  -0.855  -0.843  -0.814  -0.767
170   S         1.405   1.494   1.304   1.499   1.629   1.359   1.509   1.657   1.298
171   K        -0.791  -0.686  -0.804  -0.617  -0.453  -0.630  -0.662  -0.538  -0.656
172   S         0.608   0.467   0.381   0.740   0.537   0.394   0.605   0.385   0.234
173   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
174   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
175   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
176   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
177   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
178   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
179   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
180   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
181   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
182   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
183   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
184   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
185   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
186   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
187   H         0.608   0.691   0.450   1.068   1.175   0.862   0.605   0.729   0.345
188   R        -1.354  -1.347  -1.329  -0.841  -0.823  -0.819  -1.024  -1.012  -0.964
189   W        -0.791  -0.699  -0.810  -0.748  -0.629  -0.740  -0.662  -0.552  -0.663
190   S        -0.383  -0.331  -0.362  -0.261  -0.191  -0.202  -0.481  -0.427  -0.439
191   K        -0.383  -0.386  -0.380  -0.323  -0.347  -0.334  -0.481  -0.489  -0.461
192   I        -0.383  -0.374  -0.393  -0.600  -0.595  -0.605  -0.481  -0.462  -0.472
193   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
194   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
195   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
196   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
197   K         0.106   0.156   0.186   0.055   0.133   0.176  -0.176  -0.104  -0.077
198   N         0.863   0.953   1.013   0.572   0.738   0.812   0.467   0.640   0.701
199   D        -0.791  -0.831  -0.852  -0.569  -0.635  -0.664  -0.662  -0.706  -0.708
200   N        -0.791  -0.725  -0.834  -0.855  -0.754  -0.940  -0.662  -0.585  -0.689
201   T        -1.762  -1.736  -1.679  -1.598  -1.514  -1.473  -1.205  -1.177  -1.096
202   K        -1.354  -1.340  -1.302  -1.267  -1.263  -1.199  -1.024  -1.006  -0.941
203   H        -0.129  -0.201  -0.290   0.068  -0.071  -0.195  -0.119  -0.219  -0.328
204   V        -0.946  -0.923  -0.901  -0.854  -0.840  -0.776  -0.843  -0.817  -0.766
205   I        -0.537  -0.504  -0.470  -0.766  -0.725  -0.678  -0.662  -0.619  -0.563
206   H        -1.354  -1.360  -1.319  -1.190  -1.195  -1.125  -1.024  -1.022  -0.956
207   P        -0.537  -0.483  -0.460  -0.303  -0.240  -0.165  -0.662  -0.601  -0.554
208   Q        -0.791  -0.867  -0.855  -0.679  -0.802  -0.761  -0.662  -0.742  -0.712
209   D        -1.354  -1.300  -1.298  -1.325  -1.236  -1.247  -1.024  -0.970  -0.937
210   I        -0.791  -0.751  -0.846  -0.609  -0.569  -0.705  -0.662  -0.617  -0.702
211   E        -0.946  -0.915  -0.900  -1.258  -1.219  -1.218  -0.843  -0.807  -0.765
212   N        -0.791  -0.851  -0.878  -0.623  -0.712  -0.773  -0.662  -0.725  -0.736
213   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
214   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
215   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   E        -1.354  -1.300  -1.298  -1.415  -1.318  -1.338  -1.024  -0.970  -0.937
217   F         0.842   0.895   0.975   0.916   1.015   1.134   0.424   0.518   0.618
218   R         2.251   2.280   2.398   2.442   2.479   2.689   2.595   2.643   2.863
219   L        -1.354  -1.336  -1.302  -1.284  -1.269  -1.240  -1.024  -1.003  -0.941
220   G        -0.383  -0.461  -0.419  -0.293  -0.424  -0.365  -0.481  -0.561  -0.502
221   V         0.842   0.875   0.962   0.712   0.777   0.894   0.424   0.476   0.588
222   L         1.405   1.316   1.271   1.265   1.146   1.077   1.509   1.348   1.233
223   R         0.280   0.241   0.222   0.440   0.374   0.354   0.062  -0.017  -0.037
224   C        -0.383  -0.346  -0.382  -0.201  -0.149  -0.153  -0.481  -0.450  -0.462
225   L         2.251   2.280   2.398   2.057   2.100   2.292   2.595   2.643   2.863
226   N         0.608   0.548   0.422   0.852   0.772   0.601   0.605   0.506   0.301
227   L        -0.946  -0.956  -0.911  -1.172  -1.168  -1.096  -0.843  -0.844  -0.774
228   W        -0.383  -0.364  -0.411  -0.160  -0.170  -0.259  -0.481  -0.469  -0.496
229   I         0.608   0.717   0.472   0.491   0.643   0.290   0.605   0.769   0.380
230   K        -0.946  -0.991  -0.935  -0.919  -0.980  -0.885  -0.843  -0.875  -0.797
231   Y        -0.946  -0.991  -0.935  -0.657  -0.756  -0.671  -0.843  -0.875  -0.797
232   V         0.608   0.532   0.404   0.898   0.786   0.584   0.605   0.483   0.272
233   S         0.280   0.234   0.251   0.204   0.147   0.165   0.062   0.007   0.016
234   S        -0.946  -0.991  -0.935  -1.051  -1.118  -1.038  -0.843  -0.875  -0.797
235   K        -1.354  -1.336  -1.302  -1.217  -1.182  -1.150  -1.024  -1.003  -0.941
236   F         0.280   0.241   0.222   0.241   0.136   0.066   0.062  -0.017  -0.037
237   T        -0.537  -0.483  -0.468  -0.888  -0.811  -0.780  -0.662  -0.602  -0.561
238   T         0.025   0.051   0.114  -0.122  -0.093   0.006  -0.300  -0.266  -0.190
239   I         0.180   0.223   0.222   0.136   0.218   0.195  -0.119  -0.064  -0.050
240   Q         1.405   1.316   1.271   1.475   1.370   1.315   1.509   1.348   1.233
241   Q         0.280   0.261   0.232   0.060  -0.008  -0.039   0.062   0.008  -0.021
242   E        -0.537  -0.503  -0.454  -0.861  -0.796  -0.726  -0.662  -0.621  -0.547
243   R         2.251   2.280   2.398   2.442   2.479   2.689   2.595   2.643   2.863
244   L         1.405   1.463   1.303   1.303   1.381   1.194   1.509   1.604   1.296
245   I        -0.791  -0.783  -0.809  -0.530  -0.546  -0.564  -0.662  -0.651  -0.662
246   L         0.608   0.764   0.454   0.798   1.020   0.528   0.605   0.840   0.353
247   E         1.017   1.085   1.073   0.741   0.862   0.795   0.786   0.909   0.828
248   N        -0.129  -0.124  -0.241   0.155   0.161  -0.020  -0.119  -0.116  -0.265
249   K        -0.537  -0.504  -0.470  -0.799  -0.750  -0.673  -0.662  -0.619  -0.563
250   M        -1.354  -1.347  -1.329  -1.337  -1.340  -1.252  -1.024  -1.012  -0.964
251   N         0.461   0.558   0.370   0.478   0.644   0.289   0.378   0.525   0.216
252   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
253   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
254   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
255   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
256   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
257   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
258   M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
259   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
260   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
261   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
262   -        -0.492  -0.453  -0.447  -0.753  -0.667  -0.671  -0.607  -0.558  -0.536
263   -        -0.312  -0.299  -0.352  -0.427  -0.403  -0.467  -0.360  -0.342  -0.410
264   -        -0.492  -0.524  -0.459  -0.546  -0.594  -0.501  -0.607  -0.634  -0.549
265   L        -0.383  -0.440  -0.398  -0.453  -0.511  -0.476  -0.481  -0.531  -0.476
266   S        -0.383  -0.382  -0.381  -0.472  -0.454  -0.461  -0.481  -0.474  -0.455
267   N         1.321   1.253   1.218   1.454   1.364   1.302   1.363   1.232   1.127
268   N        -1.445  -1.423  -1.356  -1.341  -1.313  -1.208  -1.099  -1.073  -0.986
269   A        -0.537  -0.545  -0.462  -0.721  -0.736  -0.591  -0.662  -0.661  -0.554
270   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
271   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
272   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
273   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
274   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
275   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
276   D        -0.497  -0.363  -0.429  -0.692  -0.434  -0.612  -0.597  -0.425  -0.508
277   D        -1.069  -1.031  -0.974  -0.992  -0.905  -0.849  -0.951  -0.910  -0.832
278   F        -0.497  -0.436  -0.425  -0.255  -0.153  -0.139  -0.597  -0.521  -0.503
279   S        -0.968  -0.991  -0.932  -1.218  -1.223  -1.160  -0.853  -0.873  -0.791
280   A        -0.968  -0.876  -0.905  -0.803  -0.685  -0.693  -0.853  -0.753  -0.764
281   D        -0.492  -0.442  -0.442  -0.652  -0.555  -0.570  -0.607  -0.545  -0.531
282   A        -0.497  -0.498  -0.440  -0.485  -0.495  -0.389  -0.597  -0.598  -0.521
283   I        -0.497  -0.538  -0.475  -0.341  -0.397  -0.287  -0.597  -0.645  -0.564
284   D        -0.968  -0.945  -0.902  -0.981  -0.945  -0.883  -0.853  -0.824  -0.761
285   I        -0.492  -0.527  -0.439  -0.694  -0.721  -0.608  -0.607  -0.638  -0.527
286   S        -0.312  -0.280  -0.326  -0.225  -0.179  -0.238  -0.360  -0.322  -0.376
287   V         1.321   1.291   1.245   1.579   1.537   1.474   1.363   1.302   1.182
288   S         0.461   0.369   0.325   0.508   0.370   0.292   0.378   0.231   0.145
289   Q         0.842   0.862   0.958   0.517   0.551   0.690   0.424   0.447   0.581
290   S         0.280   0.212   0.233   0.254   0.148   0.181   0.062  -0.042  -0.022
291   A        -1.354  -1.347  -1.329  -1.261  -1.248  -1.195  -1.024  -1.012  -0.964
292   P        -0.946  -0.952  -0.909  -0.827  -0.867  -0.794  -0.843  -0.840  -0.772
293   V        -0.946  -0.991  -0.935  -1.087  -1.165  -1.070  -0.843  -0.875  -0.797
294   E        -0.791  -0.861  -0.863  -0.723  -0.809  -0.814  -0.662  -0.736  -0.720
295   T        -0.383  -0.369  -0.376  -0.396  -0.415  -0.382  -0.481  -0.461  -0.449
296   V        -1.354  -1.359  -1.305  -1.073  -1.067  -1.000  -1.024  -1.022  -0.944
297   Q        -0.946  -0.928  -0.902  -0.891  -0.859  -0.793  -0.843  -0.816  -0.765
298   D         0.608   0.653   0.447   0.828   0.894   0.597   0.605   0.672   0.341
299   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
300   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
301   E         1.321   1.313   1.240   1.273   1.271   1.150   1.363   1.342   1.171
302   V        -1.354  -1.360  -1.319  -1.133  -1.127  -1.076  -1.024  -1.022  -0.956
303   K         0.608   0.679   0.433   0.645   0.758   0.327   0.605   0.712   0.318
304   H        -0.946  -0.970  -0.926  -0.941  -0.987  -0.892  -0.843  -0.858  -0.788
305   Y        -0.791  -0.851  -0.878  -0.532  -0.646  -0.746  -0.662  -0.725  -0.736
306   E         0.608   0.548   0.422   0.644   0.563   0.375   0.605   0.506   0.301
307   E        -0.383  -0.364  -0.411  -0.421  -0.366  -0.441  -0.481  -0.469  -0.496
308   T         0.280   0.266   0.268   0.226   0.217   0.215   0.062   0.052   0.043
309   I        -0.968  -0.994  -0.947  -0.900  -0.940  -0.870  -0.853  -0.874  -0.806
310   S         0.280   0.284   0.235   0.190   0.175   0.116   0.062   0.054  -0.019
311   K        -0.946  -0.985  -0.906  -1.123  -1.168  -1.072  -0.843  -0.870  -0.771
312   L         1.405   1.359   1.287   1.265   1.206   1.102   1.509   1.424   1.263
313   T         0.842   0.858   0.951   0.586   0.595   0.738   0.424   0.439   0.565
314   Q        -0.129  -0.246  -0.314  -0.029  -0.192  -0.300  -0.119  -0.274  -0.360
315   E         1.405   1.452   1.301   1.374   1.445   1.217   1.509   1.586   1.290
316   Q         1.405   1.359   1.287   1.475   1.427   1.339   1.509   1.424   1.263
317   L         0.842   0.895   0.975   0.442   0.568   0.652   0.424   0.518   0.618
318   Q         2.251   2.280   2.398   2.232   2.285   2.472   2.595   2.643   2.863
319   V        -0.946  -0.952  -0.909  -0.933  -0.926  -0.886  -0.843  -0.840  -0.772
320   L         1.405   1.316   1.271   1.286   1.171   1.115   1.509   1.348   1.233
321   E         0.608   0.662   0.448   0.639   0.714   0.407   0.605   0.686   0.342
322   T         0.280   0.199   0.230   0.211   0.069   0.096   0.062  -0.052  -0.025
323   E         1.405   1.316   1.271   1.433   1.322   1.275   1.509   1.348   1.233
324   H         0.842   0.855   0.951   0.838   0.851   0.989   0.424   0.434   0.565
325   S        -0.383  -0.348  -0.383  -0.613  -0.544  -0.613  -0.481  -0.431  -0.461
326   E         1.405   1.316   1.271   1.398   1.279   1.212   1.509   1.348   1.233
327   L         0.280   0.234   0.251   0.078   0.030   0.070   0.062   0.007   0.016
328   L         0.608   0.602   0.431   0.510   0.501   0.257   0.605   0.585   0.315
329   N         0.608   0.467   0.381   0.786   0.583   0.423   0.605   0.385   0.234
330   Q        -0.946  -0.984  -0.914  -1.090  -1.114  -1.007  -0.843  -0.869  -0.777
331   K         0.608   0.467   0.381   0.700   0.489   0.321   0.605   0.385   0.234
332   N        -0.383  -0.461  -0.419  -0.482  -0.615  -0.577  -0.481  -0.561  -0.502
333   E        -0.383  -0.406  -0.406  -0.526  -0.555  -0.537  -0.481  -0.510  -0.492
334   Q        -0.129  -0.246  -0.314  -0.143  -0.328  -0.477  -0.119  -0.274  -0.360
335   L         2.251   2.280   2.398   2.057   2.100   2.292   2.595   2.643   2.863
336   K        -0.129  -0.246  -0.314   0.008  -0.163  -0.286  -0.119  -0.274  -0.360
337   K         1.017   1.069   1.083   0.851   0.946   0.926   0.786   0.876   0.848
338   V         1.405   1.434   1.290   1.685   1.728   1.540   1.509   1.555   1.269
339   E        -0.129  -0.187  -0.285   0.013  -0.075  -0.174  -0.119  -0.201  -0.322
340   T        -1.354  -1.284  -1.288  -1.396  -1.278  -1.317  -1.024  -0.954  -0.928
341   I        -0.537  -0.497  -0.462  -0.750  -0.683  -0.637  -0.662  -0.613  -0.555
342   N        -0.946  -0.894  -0.916  -0.976  -0.913  -0.917  -0.843  -0.783  -0.779
343   K        -0.383  -0.364  -0.390  -0.430  -0.419  -0.427  -0.481  -0.463  -0.474
344   T         0.842   0.895   0.975   0.571   0.656   0.776   0.424   0.518   0.618
345   I        -0.383  -0.375  -0.401  -0.477  -0.518  -0.507  -0.481  -0.480  -0.485
346   L        -0.383  -0.349  -0.356  -0.474  -0.431  -0.397  -0.481  -0.438  -0.430
347   D         0.842   0.850   0.948   0.522   0.515   0.654   0.424   0.423   0.558
348   I         2.251   2.280   2.398   2.380   2.440   2.625   2.595   2.643   2.863
349   V         0.280   0.241   0.222   0.327   0.222   0.209   0.062  -0.017  -0.037
350   N        -0.383  -0.345  -0.394  -0.457  -0.442  -0.476  -0.481  -0.449  -0.476
351   I        -0.383  -0.336  -0.353  -0.562  -0.488  -0.492  -0.481  -0.417  -0.426
352   Q         2.251   2.280   2.398   2.232   2.285   2.472   2.595   2.643   2.863
353   N         0.280   0.360   0.297   0.236   0.375   0.269   0.062   0.186   0.086
354   E         1.405   1.316   1.271   1.433   1.322   1.274   1.509   1.348   1.233
355   L         2.251   2.280   2.398   2.057   2.100   2.292   2.595   2.643   2.863
356   S        -0.383  -0.452  -0.382  -0.342  -0.450  -0.343  -0.481  -0.548  -0.462
357   N        -1.762  -1.736  -1.679  -1.351  -1.327  -1.219  -1.205  -1.177  -1.096
358   H        -0.129  -0.156  -0.289   0.253   0.210  -0.048  -0.119  -0.157  -0.328
359   L         2.251   2.280   2.398   2.057   2.100   2.292   2.595   2.643   2.863
360   T        -0.383  -0.401  -0.379  -0.537  -0.566  -0.535  -0.481  -0.501  -0.461
361   V        -0.383  -0.411  -0.407  -0.328  -0.392  -0.386  -0.481  -0.514  -0.492
362   Q         2.251   2.280   2.398   2.232   2.285   2.472   2.595   2.643   2.863
363   S         0.608   0.653   0.447   0.773   0.834   0.554   0.605   0.672   0.341
364   Q         0.280   0.199   0.230   0.061  -0.064  -0.044   0.062  -0.052  -0.025
365   N        -0.383  -0.461  -0.419  -0.417  -0.501  -0.454  -0.481  -0.561  -0.502
366   I         2.251   2.280   2.398   2.380   2.440   2.625   2.595   2.643   2.863
367   N        -0.383  -0.411  -0.407  -0.481  -0.526  -0.554  -0.481  -0.514  -0.492
368   L        -0.791  -0.783  -0.809  -0.851  -0.843  -0.923  -0.662  -0.651  -0.662
369   M         1.017   1.120   1.102   0.751   0.904   0.881   0.786   0.977   0.890
370   L        -0.383  -0.461  -0.419  -0.504  -0.598  -0.522  -0.481  -0.561  -0.502
371   N         0.280   0.209   0.236   0.276   0.174   0.196   0.062  -0.035  -0.018
372   N        -0.383  -0.461  -0.419  -0.485  -0.606  -0.564  -0.481  -0.561  -0.502
373   Q        -0.129  -0.232  -0.292  -0.015  -0.178  -0.247  -0.119  -0.257  -0.331
374   D        -1.354  -1.380  -1.332  -1.176  -1.214  -1.144  -1.024  -1.039  -0.966
375   D        -0.383  -0.390  -0.381  -0.512  -0.543  -0.535  -0.481  -0.492  -0.461
376   I         0.025   0.047   0.121  -0.081  -0.055   0.055  -0.300  -0.274  -0.179
377   E         0.280   0.254   0.236   0.058  -0.005  -0.033   0.062  -0.001  -0.015
378   L        -1.354  -1.366  -1.303  -1.297  -1.324  -1.234  -1.024  -1.028  -0.942
379   N        -0.537  -0.555  -0.460  -0.685  -0.683  -0.555  -0.662  -0.670  -0.553
380   I         0.280   0.365   0.281   0.392   0.549   0.418   0.062   0.203   0.064
381   K        -1.762  -1.736  -1.679  -1.645  -1.591  -1.522  -1.205  -1.177  -1.096
382   K        -0.791  -0.851  -0.878  -0.710  -0.804  -0.864  -0.662  -0.725  -0.736
383   G         1.405   1.359   1.287   1.795   1.730   1.646   1.509   1.424   1.263
384   N         2.251   2.280   2.398   2.367   2.424   2.611   2.595   2.643   2.863
385   K         0.842   0.875   0.962   0.617   0.665   0.799   0.424   0.476   0.588
386   E        -0.383  -0.360  -0.382  -0.586  -0.549  -0.590  -0.481  -0.454  -0.463
387   L         2.251   2.280   2.398   2.057   2.100   2.292   2.595   2.643   2.863
388   R        -0.791  -0.747  -0.812  -0.758  -0.699  -0.814  -0.662  -0.608  -0.665
389   K         0.180   0.156   0.207  -0.116  -0.138  -0.069  -0.119  -0.141  -0.069
390   A         1.405   1.316   1.271   1.640   1.496   1.445   1.509   1.348   1.233
391   K        -0.383  -0.314  -0.379  -0.466  -0.362  -0.479  -0.481  -0.401  -0.460
392   R        -0.383  -0.411  -0.407  -0.373  -0.432  -0.436  -0.481  -0.514  -0.492
393   A         0.025   0.092   0.140  -0.102  -0.003   0.065  -0.300  -0.202  -0.150
394   A         0.180   0.201   0.209   0.154   0.177   0.231  -0.119  -0.090  -0.067
395   G        -0.946  -0.991  -0.935  -0.821  -0.906  -0.810  -0.843  -0.875  -0.797
396   R         0.180   0.133   0.221   0.124   0.072   0.218  -0.119  -0.169  -0.051
397   T        -0.492  -0.519  -0.468  -0.443  -0.483  -0.432  -0.607  -0.630  -0.559
398   A         1.017   1.019   1.034   1.011   0.987   0.989   0.786   0.776   0.745
399   K        -0.537  -0.493  -0.462  -0.664  -0.582  -0.545  -0.662  -0.609  -0.555
400   M        -0.129  -0.109  -0.237   0.233   0.279   0.045  -0.119  -0.097  -0.258
401   T        -0.383  -0.360  -0.382  -0.442  -0.409  -0.460  -0.481  -0.454  -0.463
402   T        -0.946  -0.956  -0.911  -0.767  -0.766  -0.683  -0.843  -0.844  -0.774
403   Y        -1.354  -1.380  -1.332  -0.784  -0.820  -0.734  -1.024  -1.039  -0.966
404   G        -1.354  -1.334  -1.301  -1.181  -1.155  -1.102  -1.024  -0.999  -0.940
405   A         0.280   0.266   0.268   0.457   0.422   0.444   0.062   0.052   0.043
406   I        -0.129  -0.187  -0.285   0.013  -0.093  -0.270  -0.119  -0.201  -0.322
407   I        -0.791  -0.851  -0.878  -0.503  -0.573  -0.617  -0.662  -0.725  -0.736
408   M        -0.129   0.009  -0.254  -0.111   0.077  -0.249  -0.119   0.066  -0.281
409   G         0.608   0.467   0.381   1.082   0.884   0.775   0.605   0.385   0.234
410   V        -0.791  -0.831  -0.852  -0.583  -0.653  -0.713  -0.662  -0.706  -0.708
411   F         1.017   1.011   1.020   0.720   0.706   0.712   0.786   0.759   0.715
412   I         1.017   1.120   1.102   0.671   0.842   0.790   0.786   0.977   0.890
413   L         1.017   0.992   1.020   0.707   0.661   0.694   0.786   0.722   0.715
414   F         0.842   0.862   0.952   0.544   0.568   0.678   0.424   0.447   0.567
415   L        -0.791  -0.867  -0.855  -0.680  -0.745  -0.702  -0.662  -0.742  -0.712
416   D         2.251   2.280   2.398   2.378   2.426   2.622   2.595   2.643   2.863
417   Y         1.405   1.316   1.271   1.750   1.617   1.527   1.509   1.348   1.233
418   V         0.280   0.278   0.279   0.354   0.382   0.369   0.062   0.074   0.052
419   G        -0.791  -0.843  -0.855  -0.580  -0.655  -0.655  -0.662  -0.717  -0.712
420   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P41834
Output conservation file - output/P41834
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
