1     M         0.911   0.954   1.011   1.085   1.131   1.202   0.956   1.011   1.092
2     G        -1.131  -1.190  -0.980  -1.325  -1.381  -1.033  -1.355  -1.348  -1.053
3     K         0.911   0.954   1.011   0.709   0.779   0.894   0.956   1.011   1.092
4     A         0.122   0.026  -0.166   0.154   0.033  -0.264   0.105  -0.038  -0.373
5     A        -2.221  -1.929  -1.910  -2.230  -1.819  -1.759  -1.964  -1.634  -1.493
6     K        -1.339  -1.285  -1.478  -1.383  -1.326  -1.585  -1.234  -1.150  -1.300
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     K         0.122   0.026  -0.166   0.017  -0.087  -0.356   0.105  -0.038  -0.373
10    K         0.122   0.026  -0.166   0.017  -0.089  -0.358   0.105  -0.038  -0.373
11    Y        -1.720  -1.774  -1.517  -1.558  -1.619  -1.275  -1.720  -1.673  -1.340
12    S        -0.631  -0.943  -0.956  -0.431  -0.871  -0.935  -0.625  -1.021  -1.021
13    G        -0.976  -0.849  -0.942  -0.974  -0.771  -0.940  -1.112  -0.892  -1.004
14    A        -0.976  -0.900  -0.975  -1.040  -1.006  -1.020  -1.112  -1.052  -1.048
15    T        -1.631  -1.616  -1.507  -1.572  -1.524  -1.402  -1.599  -1.510  -1.329
16    S        -2.358  -2.092  -1.925  -2.267  -1.880  -1.624  -2.085  -1.776  -1.504
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    S        -2.181  -1.786  -1.907  -2.047  -1.497  -1.682  -1.904  -1.466  -1.489
23    K        -2.181  -2.080  -1.938  -2.242  -2.108  -1.817  -1.904  -1.761  -1.513
24    Q        -2.753  -2.500  -2.277  -2.607  -2.250  -1.970  -2.222  -1.935  -1.626
25    V        -0.758  -1.029  -0.980  -0.805  -1.222  -1.127  -0.792  -1.143  -1.051
26    S        -1.922  -1.587  -1.519  -2.055  -1.540  -1.419  -1.904  -1.493  -1.341
27    A        -0.343  -0.426  -0.261  -0.526  -0.715  -0.416  -0.633  -0.792  -0.539
28    E        -0.631  -0.943  -0.956  -0.490  -0.986  -1.063  -0.625  -1.021  -1.021
29    K        -1.339  -1.601  -1.511  -1.327  -1.708  -1.518  -1.234  -1.494  -1.333
30    H        -1.339  -1.601  -1.511  -0.923  -1.363  -1.330  -1.234  -1.494  -1.333
31    L        -1.339  -1.601  -1.511  -1.371  -1.740  -1.611  -1.234  -1.494  -1.333
32    S        -1.131  -0.903  -0.961  -1.235  -0.890  -0.936  -1.355  -1.049  -1.031
33    S        -1.631  -1.719  -1.515  -1.571  -1.687  -1.413  -1.599  -1.625  -1.338
34    V         0.122  -0.115  -0.190   0.046  -0.265  -0.386   0.105  -0.258  -0.414
35    F         0.911   0.954   1.011   0.972   1.029   1.110   0.956   1.011   1.092
36    K         0.911   0.954   1.011   0.709   0.779   0.894   0.956   1.011   1.092
37    F         0.122   0.136  -0.171   0.301   0.330  -0.111   0.105   0.126  -0.381
38    N         0.122  -0.115  -0.190   0.246  -0.074  -0.213   0.105  -0.258  -0.414
39    T        -0.267  -0.395  -0.258  -0.369  -0.655  -0.468  -0.504  -0.735  -0.533
40    D        -0.267   0.001  -0.197  -0.274   0.130  -0.210  -0.504  -0.076  -0.425
41    L        -0.267  -0.395  -0.258  -0.522  -0.714  -0.476  -0.504  -0.735  -0.533
42    G         0.911   0.954   1.011   0.930   0.972   1.075   0.956   1.011   1.092
43    Q         0.911   0.954   1.011   1.014   1.074   1.144   0.956   1.011   1.092
44    H         0.911   0.954   1.011   1.153   1.201   1.258   0.956   1.011   1.092
45    I         0.911   0.954   1.011   0.899   0.969   1.050   0.956   1.011   1.092
46    L         0.911   0.954   1.011   0.712   0.793   0.896   0.956   1.011   1.092
47    K         0.911   0.954   1.011   0.709   0.779   0.894   0.956   1.011   1.092
48    N         0.911   0.954   1.011   0.932   0.987   1.077   0.956   1.011   1.092
49    P         0.911   0.954   1.011   0.925   0.981   1.071   0.956   1.011   1.092
50    L         0.122  -0.115  -0.190   0.019  -0.282  -0.396   0.105  -0.258  -0.414
51    V         0.122  -0.115  -0.190   0.046  -0.265  -0.386   0.105  -0.258  -0.414
52    A         0.122  -0.115  -0.190   0.161  -0.159  -0.288   0.105  -0.258  -0.414
53    Q         0.122  -0.115  -0.190   0.328   0.010  -0.154   0.105  -0.258  -0.414
54    G         0.122  -0.115  -0.190   0.226  -0.126  -0.269   0.105  -0.258  -0.414
55    I         0.911   0.954   1.011   0.899   0.969   1.050   0.956   1.011   1.092
56    V         0.911   0.954   1.011   0.744   0.812   0.922   0.956   1.011   1.092
57    D         0.911   0.954   1.011   0.981   1.035   1.117   0.956   1.011   1.092
58    K         0.911   0.954   1.011   0.709   0.779   0.894   0.956   1.011   1.092
59    A         0.122   0.136  -0.171   0.161   0.188  -0.255   0.105   0.126  -0.381
60    Q        -1.631  -1.634  -1.514  -1.472  -1.511  -1.321  -1.599  -1.566  -1.337
61    I        -0.267  -0.395  -0.258  -0.424  -0.698  -0.504  -0.504  -0.735  -0.533
62    R         0.122   0.311  -0.157   0.017   0.265  -0.341   0.105   0.367  -0.358
63    P         0.122   0.026  -0.166   0.244   0.130  -0.165   0.105  -0.038  -0.373
64    S         0.122  -0.115  -0.190   0.254  -0.046  -0.216   0.105  -0.258  -0.414
65    D         0.911   0.954   1.011   0.981   1.035   1.117   0.956   1.011   1.092
66    V        -1.268  -1.245  -1.005  -1.510  -1.487  -1.126  -1.477  -1.412  -1.082
67    V         0.911   0.954   1.011   0.744   0.812   0.922   0.956   1.011   1.092
68    L         0.122  -0.115  -0.190  -0.009  -0.329  -0.477   0.105  -0.258  -0.414
69    E         0.911   0.954   1.011   0.934   0.991   1.079   0.956   1.011   1.092
70    V         0.122   0.329  -0.158   0.046   0.314  -0.332   0.105   0.390  -0.359
71    G         0.911   0.954   1.011   0.930   0.972   1.075   0.956   1.011   1.092
72    P         0.911   0.954   1.011   0.925   0.981   1.071   0.956   1.011   1.092
73    G         0.911   0.954   1.011   0.930   0.972   1.075   0.956   1.011   1.092
74    T         0.911   0.954   1.011   0.956   1.027   1.096   0.956   1.011   1.092
75    G         0.911   0.954   1.011   0.930   0.972   1.075   0.956   1.011   1.092
76    N         0.911   0.954   1.011   0.932   0.987   1.077   0.956   1.011   1.092
77    L         0.122  -0.115  -0.190   0.014  -0.283  -0.410   0.105  -0.258  -0.414
78    T         0.911   0.954   1.011   0.956   1.027   1.096   0.956   1.011   1.092
79    V         0.911   0.954   1.011   0.744   0.812   0.922   0.956   1.011   1.092
80    R         0.911   0.954   1.011   0.937   0.997   1.081   0.956   1.011   1.092
81    I        -0.631  -0.943  -0.956  -0.463  -0.901  -0.932  -0.625  -1.021  -1.021
82    L         0.911   0.954   1.011   0.712   0.793   0.896   0.956   1.011   1.092
83    E         0.911   0.954   1.011   0.934   0.991   1.079   0.956   1.011   1.092
84    Q        -0.542  -0.369  -0.241  -0.928  -0.659  -0.436  -0.990  -0.689  -0.503
85    A         0.911   0.954   1.011   0.852   0.905   1.011   0.956   1.011   1.092
86    K        -0.267  -0.307  -0.254  -0.388  -0.490  -0.469  -0.504  -0.581  -0.526
87    N         0.122   0.311  -0.157   0.017   0.263  -0.343   0.105   0.367  -0.358
88    V         0.911   0.954   1.011   0.744   0.812   0.922   0.956   1.011   1.092
89    V        -0.475  -0.228  -0.220  -0.824  -0.352  -0.399  -0.869  -0.446  -0.467
90    A         0.911   0.954   1.011   0.852   0.905   1.011   0.956   1.011   1.092
91    V        -0.631  -0.693  -0.940  -0.634  -0.736  -1.050  -0.625  -0.728  -1.001
92    E         0.911   0.954   1.011   0.934   0.991   1.079   0.956   1.011   1.092
93    M        -0.631  -0.689  -0.941  -0.320  -0.475  -0.882  -0.625  -0.724  -1.002
94    D         0.911   0.954   1.011   0.981   1.035   1.117   0.956   1.011   1.092
95    P         0.911   0.954   1.011   0.925   0.981   1.071   0.956   1.011   1.092
96    R         0.911   0.954   1.011   0.937   0.997   1.081   0.956   1.011   1.092
97    M         0.911   0.954   1.011   1.085   1.131   1.202   0.956   1.011   1.092
98    A         0.122  -0.115  -0.190   0.159  -0.172  -0.293   0.105  -0.258  -0.414
99    A         0.911   0.954   1.011   0.852   0.905   1.011   0.956   1.011   1.092
100   E         0.911   0.954   1.011   0.934   0.991   1.079   0.956   1.011   1.092
101   L        -0.631  -0.943  -0.956  -0.701  -1.148  -1.180  -0.625  -1.021  -1.021
102   T         0.911   0.954   1.011   0.956   1.027   1.096   0.956   1.011   1.092
103   K         0.911   0.954   1.011   0.709   0.779   0.894   0.956   1.011   1.092
104   R         0.911   0.954   1.011   0.937   0.997   1.081   0.956   1.011   1.092
105   V         0.911   0.954   1.011   0.744   0.812   0.922   0.956   1.011   1.092
106   R        -1.131  -0.906  -0.966  -1.029  -0.741  -0.804  -1.355  -1.055  -1.036
107   G         0.911   0.954   1.011   0.930   0.972   1.075   0.956   1.011   1.092
108   T         0.122   0.136  -0.171   0.232   0.270  -0.268   0.105   0.126  -0.381
109   P         0.911   0.954   1.011   0.925   0.981   1.071   0.956   1.011   1.092
110   V        -3.084  -2.814  -2.560  -3.150  -2.828  -2.357  -2.329  -2.040  -1.703
111   E        -0.976  -1.071  -0.977  -0.948  -1.088  -0.967  -1.112  -1.186  -1.048
112   K         0.911   0.954   1.011   0.709   0.779   0.894   0.956   1.011   1.092
113   K         0.911   0.954   1.011   0.709   0.779   0.894   0.956   1.011   1.092
114   L         0.911   0.954   1.011   0.712   0.793   0.896   0.956   1.011   1.092
115   E        -0.631  -0.565  -0.916  -0.419  -0.339  -0.826  -0.625  -0.543  -0.970
116   I        -0.267  -0.395  -0.258  -0.414  -0.687  -0.486  -0.504  -0.735  -0.533
117   M        -1.720  -1.774  -1.516  -1.843  -1.871  -1.510  -1.720  -1.673  -1.338
118   L         0.911   0.954   1.011   0.712   0.793   0.896   0.956   1.011   1.092
119   G         0.911   0.954   1.011   0.930   0.972   1.075   0.956   1.011   1.092
120   D         0.911   0.954   1.011   0.981   1.035   1.117   0.956   1.011   1.092
121   F        -0.976  -1.053  -0.983  -0.949  -1.152  -0.970  -1.112  -1.209  -1.057
122   M        -0.542  -0.361  -0.239  -0.741  -0.450  -0.270  -0.990  -0.675  -0.500
123   K         0.911   0.954   1.011   0.709   0.779   0.894   0.956   1.011   1.092
124   T         0.122  -0.115  -0.190   0.285  -0.008  -0.154   0.105  -0.258  -0.414
125   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
126   E        -0.267  -0.199  -0.230  -0.304  -0.203  -0.282  -0.504  -0.397  -0.484
127   L         0.122  -0.115  -0.190   0.042  -0.235  -0.329   0.105  -0.258  -0.414
128   P         0.911   0.954   1.011   0.925   0.981   1.071   0.956   1.011   1.092
129   Y         0.122  -0.115  -0.190   0.461   0.119  -0.074   0.105  -0.258  -0.414
130   F         0.122  -0.115  -0.190   0.315   0.019  -0.101   0.105  -0.258  -0.414
131   D         0.911   0.954   1.011   0.981   1.035   1.117   0.956   1.011   1.092
132   I        -1.131  -1.119  -0.969  -1.450  -1.373  -1.130  -1.355  -1.251  -1.039
133   C         0.122  -0.115  -0.190   0.461   0.086  -0.136   0.105  -0.258  -0.414
134   I         0.122   0.026  -0.166   0.180   0.064  -0.288   0.105  -0.038  -0.373
135   S         0.911   0.954   1.011   0.944   1.018   1.087   0.956   1.011   1.092
136   N         0.911   0.954   1.011   0.932   0.987   1.077   0.956   1.011   1.092
137   T         0.911   0.954   1.011   0.956   1.027   1.096   0.956   1.011   1.092
138   P         0.911   0.954   1.011   0.925   0.981   1.071   0.956   1.011   1.092
139   Y         0.911   0.954   1.011   1.155   1.202   1.260   0.956   1.011   1.092
140   Q         0.911   0.954   1.011   1.014   1.074   1.144   0.956   1.011   1.092
141   I         0.911   0.954   1.011   0.899   0.969   1.050   0.956   1.011   1.092
142   S         0.911   0.954   1.011   0.944   1.018   1.087   0.956   1.011   1.092
143   S         0.911   0.954   1.011   0.944   1.018   1.087   0.956   1.011   1.092
144   P         0.911   0.954   1.011   0.925   0.981   1.071   0.956   1.011   1.092
145   L         0.911   0.954   1.011   0.712   0.793   0.896   0.956   1.011   1.092
146   V         0.122  -0.115  -0.190   0.046  -0.265  -0.386   0.105  -0.258  -0.414
147   F         0.911   0.954   1.011   0.972   1.029   1.110   0.956   1.011   1.092
148   K         0.911   0.954   1.011   0.709   0.779   0.894   0.956   1.011   1.092
149   L         0.122  -0.115  -0.190   0.042  -0.235  -0.329   0.105  -0.258  -0.414
150   I        -0.475  -0.228  -0.220  -0.908  -0.464  -0.461  -0.869  -0.446  -0.467
151   N        -0.631  -0.943  -0.956  -0.442  -0.899  -0.940  -0.625  -1.021  -1.021
152   Q         0.122  -0.115  -0.190   0.342   0.037  -0.112   0.105  -0.258  -0.414
153   P         0.122   0.026  -0.166   0.233   0.113  -0.194   0.105  -0.038  -0.373
154   R        -1.339  -1.466  -1.498  -1.148  -1.362  -1.458  -1.234  -1.368  -1.320
155   P         0.122   0.026  -0.166   0.221   0.094  -0.227   0.105  -0.038  -0.373
156   P         0.911   0.954   1.011   0.925   0.981   1.071   0.956   1.011   1.092
157   R         0.911   0.954   1.011   0.937   0.997   1.081   0.956   1.011   1.092
158   V         0.122   0.026  -0.166   0.039  -0.074  -0.364   0.105  -0.038  -0.373
159   S        -0.267  -0.395  -0.258  -0.336  -0.592  -0.397  -0.504  -0.735  -0.533
160   I        -0.267  -0.363  -0.258  -0.414  -0.618  -0.488  -0.504  -0.679  -0.534
161   L         0.911   0.954   1.011   0.712   0.793   0.896   0.956   1.011   1.092
162   M         0.911   0.954   1.011   1.085   1.131   1.202   0.956   1.011   1.092
163   F         0.911   0.954   1.011   0.972   1.029   1.110   0.956   1.011   1.092
164   Q         0.911   0.954   1.011   1.014   1.074   1.144   0.956   1.011   1.092
165   R         0.122   0.136  -0.171   0.276   0.309  -0.110   0.105   0.126  -0.381
166   E         0.911   0.954   1.011   0.934   0.991   1.079   0.956   1.011   1.092
167   F         0.911   0.954   1.011   0.972   1.029   1.110   0.956   1.011   1.092
168   A         0.911   0.954   1.011   0.852   0.905   1.011   0.956   1.011   1.092
169   L        -1.631  -1.588  -1.505  -1.563  -1.607  -1.458  -1.599  -1.520  -1.329
170   R         0.911   0.954   1.011   0.937   0.997   1.081   0.956   1.011   1.092
171   L         0.911   0.954   1.011   0.712   0.793   0.896   0.956   1.011   1.092
172   L        -0.475  -0.435  -0.261  -0.994  -0.926  -0.614  -0.869  -0.808  -0.538
173   A         0.911   0.954   1.011   0.852   0.905   1.011   0.956   1.011   1.092
174   R         0.911   0.954   1.011   0.937   0.997   1.081   0.956   1.011   1.092
175   P         0.911   0.954   1.011   0.925   0.981   1.071   0.956   1.011   1.092
176   G         0.911   0.954   1.011   0.930   0.972   1.075   0.956   1.011   1.092
177   D         0.122   0.358  -0.155   0.289   0.572  -0.134   0.105   0.429  -0.354
178   S        -1.339  -1.444  -1.496  -1.113  -1.314  -1.395  -1.234  -1.348  -1.319
179   L         0.911   0.954   1.011   0.712   0.793   0.896   0.956   1.011   1.092
180   Y         0.911   0.954   1.011   1.155   1.202   1.260   0.956   1.011   1.092
181   C         0.122  -0.115  -0.190   0.492   0.146  -0.046   0.105  -0.258  -0.414
182   R         0.911   0.954   1.011   0.937   0.997   1.081   0.956   1.011   1.092
183   L         0.911   0.954   1.011   0.712   0.793   0.896   0.956   1.011   1.092
184   S         0.911   0.954   1.011   0.944   1.018   1.087   0.956   1.011   1.092
185   A        -0.267  -0.363  -0.258  -0.460  -0.676  -0.519  -0.504  -0.679  -0.534
186   N         0.911   0.954   1.011   0.932   0.987   1.077   0.956   1.011   1.092
187   V         0.911   0.954   1.011   0.744   0.812   0.922   0.956   1.011   1.092
188   Q         0.122  -0.115  -0.190   0.321  -0.003  -0.174   0.105  -0.258  -0.414
189   M         0.122  -0.115  -0.190   0.397   0.064  -0.107   0.105  -0.258  -0.414
190   W         0.911   0.954   1.011   1.214   1.254   1.308   0.956   1.011   1.092
191   A         0.911   0.954   1.011   0.852   0.905   1.011   0.956   1.011   1.092
192   N        -1.339  -1.601  -1.511  -1.102  -1.478  -1.381  -1.234  -1.494  -1.333
193   V         0.122  -0.115  -0.190   0.089  -0.190  -0.262   0.105  -0.258  -0.414
194   T        -0.976  -1.053  -0.983  -1.024  -1.225  -1.094  -1.112  -1.209  -1.057
195   H         0.911   0.954   1.011   1.153   1.201   1.258   0.956   1.011   1.092
196   I         0.122   0.136  -0.171   0.180   0.218  -0.298   0.105   0.126  -0.381
197   M         0.911   0.954   1.011   1.085   1.131   1.202   0.956   1.011   1.092
198   K         0.911   0.954   1.011   0.709   0.779   0.894   0.956   1.011   1.092
199   V         0.911   0.954   1.011   0.744   0.812   0.922   0.956   1.011   1.092
200   G         0.122   0.325  -0.157   0.239   0.476  -0.173   0.105   0.385  -0.358
201   K        -0.267  -0.118  -0.228  -0.536  -0.294  -0.456  -0.504  -0.263  -0.480
202   N        -0.631  -0.854  -0.956  -0.430  -0.741  -0.908  -0.625  -0.911  -1.020
203   N         0.911   0.954   1.011   0.932   0.987   1.077   0.956   1.011   1.092
204   F         0.911   0.954   1.011   0.972   1.029   1.110   0.956   1.011   1.092
205   R         0.122  -0.115  -0.190   0.213  -0.136  -0.322   0.105  -0.258  -0.414
206   P         0.911   0.954   1.011   0.925   0.981   1.071   0.956   1.011   1.092
207   P         0.911   0.954   1.011   0.925   0.981   1.071   0.956   1.011   1.092
208   P         0.911   0.954   1.011   0.925   0.981   1.071   0.956   1.011   1.092
209   Q        -1.631  -1.680  -1.509  -1.648  -1.792  -1.552  -1.599  -1.590  -1.333
210   V         0.911   0.954   1.011   0.744   0.812   0.922   0.956   1.011   1.092
211   E         0.911   0.954   1.011   0.934   0.991   1.079   0.956   1.011   1.092
212   S         0.911   0.954   1.011   0.944   1.018   1.087   0.956   1.011   1.092
213   S         0.122  -0.115  -0.190   0.258  -0.044  -0.205   0.105  -0.258  -0.414
214   V         0.911   0.954   1.011   0.744   0.812   0.922   0.956   1.011   1.092
215   V         0.911   0.954   1.011   0.744   0.812   0.922   0.956   1.011   1.092
216   R         0.122   0.136  -0.171   0.213   0.240  -0.283   0.105   0.126  -0.381
217   L         0.122   0.311  -0.157   0.175   0.433  -0.283   0.105   0.367  -0.358
218   E         0.911   0.954   1.011   0.934   0.991   1.079   0.956   1.011   1.092
219   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   I        -1.131  -1.110  -0.970  -1.401  -1.345  -1.102  -1.355  -1.261  -1.041
222   K         0.122  -0.115  -0.190   0.016  -0.296  -0.398   0.105  -0.258  -0.414
223   N        -0.631  -0.693  -0.940  -0.471  -0.578  -0.982  -0.625  -0.728  -1.001
224   P         0.122  -0.115  -0.190   0.221  -0.117  -0.272   0.105  -0.258  -0.414
225   R         0.122   0.026  -0.166   0.243   0.126  -0.190   0.105  -0.038  -0.373
226   P         0.911   0.954   1.011   0.925   0.981   1.071   0.956   1.011   1.092
227   Q        -1.357  -1.222  -0.998  -1.523  -1.316  -0.979  -1.599  -1.383  -1.074
228   V        -0.976  -0.872  -0.945  -1.110  -0.901  -1.108  -1.112  -0.923  -1.007
229   D        -0.267  -0.395  -0.258  -0.300  -0.577  -0.373  -0.504  -0.735  -0.533
230   Y         0.122   0.311  -0.157   0.311   0.538  -0.062   0.105   0.367  -0.358
231   N        -0.267  -0.395  -0.258  -0.321  -0.570  -0.358  -0.504  -0.735  -0.533
232   E         0.911   0.954   1.011   0.934   0.991   1.079   0.956   1.011   1.092
233   W         0.122  -0.115  -0.190   0.525   0.182  -0.014   0.105  -0.258  -0.414
234   D         0.911   0.954   1.011   0.981   1.035   1.117   0.956   1.011   1.092
235   G         0.911   0.954   1.011   0.930   0.972   1.075   0.956   1.011   1.092
236   L         0.911   0.954   1.011   0.712   0.793   0.896   0.956   1.011   1.092
237   L         0.911   0.954   1.011   0.712   0.793   0.896   0.956   1.011   1.092
238   R         0.911   0.954   1.011   0.937   0.997   1.081   0.956   1.011   1.092
239   I         0.122   0.136  -0.171   0.180   0.218  -0.298   0.105   0.126  -0.381
240   V        -0.976  -1.071  -0.977  -1.059  -1.189  -0.993  -1.112  -1.186  -1.048
241   F         0.911   0.954   1.011   0.972   1.029   1.110   0.956   1.011   1.092
242   V        -0.631  -0.943  -0.956  -0.668  -1.115  -1.157  -0.625  -1.021  -1.021
243   R         0.911   0.954   1.011   0.937   0.997   1.081   0.956   1.011   1.092
244   K         0.911   0.954   1.011   0.709   0.779   0.894   0.956   1.011   1.092
245   N         0.911   0.954   1.011   0.932   0.987   1.077   0.956   1.011   1.092
246   R        -0.475  -0.228  -0.220  -0.889  -0.467  -0.444  -0.869  -0.446  -0.467
247   T         0.911   0.954   1.011   0.956   1.027   1.096   0.956   1.011   1.092
248   I         0.122  -0.115  -0.190   0.175  -0.160  -0.349   0.105  -0.258  -0.414
249   S        -2.221  -2.220  -1.935  -2.120  -2.038  -1.649  -1.964  -1.862  -1.512
250   A         0.911   0.954   1.011   0.852   0.905   1.011   0.956   1.011   1.092
251   G         0.122   0.026  -0.166   0.274   0.152  -0.095   0.105  -0.038  -0.373
252   F         0.911   0.954   1.011   0.972   1.029   1.110   0.956   1.011   1.092
253   K         0.122  -0.115  -0.190   0.017  -0.292  -0.397   0.105  -0.258  -0.414
254   S        -0.976  -1.165  -0.986  -0.930  -1.182  -0.942  -1.112  -1.314  -1.060
255   T        -1.720  -1.614  -1.506  -1.773  -1.625  -1.451  -1.720  -1.541  -1.329
256   T        -2.221  -2.220  -1.937  -2.121  -2.096  -1.717  -1.964  -1.862  -1.513
257   V        -0.267  -0.214  -0.233  -0.515  -0.423  -0.460  -0.504  -0.422  -0.489
258   M        -0.976  -0.779  -0.949  -1.157  -0.872  -1.034  -1.112  -0.854  -1.014
259   D        -1.631  -1.634  -1.508  -1.568  -1.566  -1.395  -1.599  -1.530  -1.330
260   I        -0.976  -1.053  -0.983  -0.973  -1.083  -0.994  -1.112  -1.209  -1.057
261   L        -0.631  -0.943  -0.956  -0.650  -1.040  -1.054  -0.625  -1.021  -1.021
262   E         0.911   0.954   1.011   0.934   0.991   1.079   0.956   1.011   1.092
263   K        -0.631  -0.943  -0.956  -0.664  -1.088  -1.085  -0.625  -1.021  -1.021
264   N         0.911   0.954   1.011   0.932   0.987   1.077   0.956   1.011   1.092
265   Y         0.911   0.954   1.011   1.155   1.202   1.260   0.956   1.011   1.092
266   K        -0.631  -0.733  -0.933  -0.650  -0.764  -1.020  -0.625  -0.743  -0.992
267   T        -0.631  -0.689  -0.941  -0.463  -0.588  -1.005  -0.625  -0.724  -1.002
268   F        -0.976  -1.165  -0.986  -0.781  -1.003  -0.740  -1.112  -1.314  -1.060
269   L        -0.267  -0.395  -0.258  -0.449  -0.600  -0.352  -0.504  -0.735  -0.533
270   A        -1.131  -1.189  -0.979  -1.310  -1.321  -1.007  -1.355  -1.348  -1.052
271   M        -1.995  -1.935  -1.918  -1.726  -1.723  -1.666  -1.720  -1.637  -1.498
272   N        -1.131  -0.858  -0.963  -1.223  -0.820  -0.944  -1.355  -0.984  -1.033
273   N        -1.631  -1.444  -1.493  -1.571  -1.315  -1.363  -1.599  -1.356  -1.317
274   E        -2.721  -2.493  -2.267  -2.594  -2.280  -1.923  -2.207  -1.941  -1.619
275   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
276   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
277   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
278   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
279   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
280   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
281   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
282   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
283   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
284   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
285   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
286   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
287   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
288   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
289   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
290   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
291   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
292   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
293   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
294   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
295   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
296   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
297   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
298   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
299   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
300   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
301   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
302   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
303   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
304   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
305   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
306   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
307   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
308   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
309   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
310   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
311   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
312   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
313   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
314   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
315   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
316   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
317   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
318   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
319   M        -1.995  -1.856  -1.915  -1.620  -1.509  -1.614  -1.720  -1.560  -1.495
320   V        -1.631  -1.557  -1.506  -1.719  -1.570  -1.440  -1.599  -1.473  -1.329
321   D        -1.631  -1.519  -1.510  -1.528  -1.422  -1.367  -1.599  -1.459  -1.333
322   D        -1.131  -0.795  -0.949  -1.222  -0.712  -0.904  -1.355  -0.887  -1.014
323   T        -1.995  -1.709  -1.526  -2.204  -1.706  -1.472  -1.964  -1.604  -1.347
324   K        -2.221  -2.019  -1.919  -2.147  -1.856  -1.717  -1.964  -1.720  -1.500
325   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
326   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
327   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
328   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
329   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
330   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
331   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
332   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
333   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
334   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
335   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
336   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
337   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
339   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
340   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
341   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
342   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
343   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
344   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
345   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
346   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
347   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
348   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
349   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
350   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
351   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
352   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
353   S        -1.092  -1.191  -0.991  -1.197  -1.391  -1.094  -1.268  -1.343  -1.066
354   M        -1.092  -1.138  -0.983  -1.318  -1.394  -1.113  -1.268  -1.276  -1.056
355   H        -3.168  -2.797  -2.562  -2.951  -2.438  -2.108  -2.381  -2.019  -1.704
356   D        -1.507  -1.398  -1.503  -1.346  -1.303  -1.431  -1.427  -1.316  -1.325
357   V        -1.766  -1.468  -1.506  -2.015  -1.571  -1.584  -1.745  -1.415  -1.330
358   V         0.122   0.373  -0.155   0.046   0.362  -0.327   0.105   0.448  -0.354
359   K         0.911   0.954   1.011   0.709   0.779   0.894   0.956   1.011   1.092
360   E        -2.358  -2.125  -1.927  -2.327  -1.995  -1.687  -2.085  -1.798  -1.505
361   K         0.122   0.026  -0.166  -0.016  -0.131  -0.446   0.105  -0.038  -0.373
362   I         0.122  -0.115  -0.190   0.175  -0.160  -0.349   0.105  -0.258  -0.414
363   D        -1.858  -1.632  -1.519  -1.895  -1.589  -1.375  -1.842  -1.570  -1.341
364   T        -1.858  -1.734  -1.520  -1.980  -1.829  -1.476  -1.842  -1.634  -1.342
365   V         0.122   0.136  -0.171   0.046   0.086  -0.354   0.105   0.126  -0.381
366   L         0.911   0.954   1.011   0.712   0.793   0.896   0.956   1.011   1.092
367   K        -1.631  -1.385  -1.482  -1.631  -1.197  -1.388  -1.599  -1.268  -1.305
368   E        -1.339  -1.601  -1.511  -1.078  -1.454  -1.336  -1.234  -1.494  -1.333
369   T         0.122   0.026  -0.166   0.299   0.206  -0.076   0.105  -0.038  -0.373
370   D        -0.631  -0.577  -0.916  -0.437  -0.392  -0.858  -0.625  -0.557  -0.970
371   L        -0.976  -0.755  -0.944  -1.165  -0.795  -1.064  -1.112  -0.773  -1.007
372   G        -1.858  -1.700  -1.511  -1.963  -1.695  -1.405  -1.842  -1.596  -1.334
373   D        -0.475  -0.303  -0.244  -0.651  -0.356  -0.300  -0.869  -0.574  -0.509
374   K        -0.631  -0.733  -0.933  -0.652  -0.775  -1.025  -0.625  -0.743  -0.992
375   R         0.911   0.954   1.011   0.937   0.997   1.081   0.956   1.011   1.092
376   A         0.122   0.136  -0.171   0.161   0.188  -0.255   0.105   0.126  -0.381
377   G        -1.631  -1.751  -1.518  -1.609  -1.781  -1.439  -1.599  -1.648  -1.340
378   K         0.122  -0.115  -0.190   0.029  -0.266  -0.362   0.105  -0.258  -0.414
379   C        -0.267   0.001  -0.197  -0.146   0.271  -0.151  -0.504  -0.076  -0.425
380   D         0.122   0.026  -0.166   0.288   0.162  -0.155   0.105  -0.038  -0.373
381   Q         0.911   0.954   1.011   1.014   1.074   1.144   0.956   1.011   1.092
382   N        -0.267  -0.307  -0.254  -0.299  -0.372  -0.337  -0.504  -0.581  -0.526
383   D        -0.267  -0.297  -0.245  -0.274  -0.344  -0.302  -0.504  -0.563  -0.510
384   F         0.911   0.954   1.011   0.972   1.029   1.110   0.956   1.011   1.092
385   L         0.911   0.954   1.011   0.712   0.793   0.896   0.956   1.011   1.092
386   R        -1.339  -1.296  -1.477  -1.320  -1.247  -1.464  -1.234  -1.161  -1.299
387   L         0.911   0.954   1.011   0.712   0.793   0.896   0.956   1.011   1.092
388   L         0.911   0.954   1.011   0.712   0.793   0.896   0.956   1.011   1.092
389   Y        -1.339  -1.601  -1.511  -0.890  -1.335  -1.265  -1.234  -1.494  -1.333
390   A        -0.631  -0.459  -0.921  -0.523  -0.306  -0.938  -0.625  -0.398  -0.976
391   F         0.911   0.954   1.011   0.972   1.029   1.110   0.956   1.011   1.092
392   H         0.911   0.954   1.011   1.153   1.201   1.258   0.956   1.011   1.092
393   Q        -0.631  -0.854  -0.956  -0.397  -0.726  -0.974  -0.625  -0.911  -1.020
394   V        -0.631  -0.854  -0.956  -0.644  -0.952  -1.096  -0.625  -0.911  -1.020
395   G         0.911   0.954   1.011   0.930   0.972   1.075   0.956   1.011   1.092
396   I        -0.631  -0.565  -0.916  -0.543  -0.453  -1.050  -0.625  -0.543  -0.970
397   H         0.122   0.136  -0.171   0.490   0.511   0.047   0.105   0.126  -0.381
398   F         0.911   0.954   1.011   0.972   1.029   1.110   0.956   1.011   1.092
399   S        -0.475  -0.401  -0.259  -0.760  -0.636  -0.406  -0.869  -0.747  -0.535
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P41819
Output conservation file - output/P41819
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
