1     M         0.926   0.937   0.974   1.124   1.137   1.180   0.978   0.991   1.043
2     E        -1.352  -1.372  -1.236  -1.399  -1.402  -1.188  -1.379  -1.384  -1.196
3     E        -1.748  -1.694  -1.597  -1.729  -1.650  -1.483  -1.561  -1.496  -1.351
4     Q        -1.203  -1.225  -1.216  -1.166  -1.205  -1.196  -1.198  -1.219  -1.175
5     E        -1.203  -1.216  -1.219  -1.194  -1.206  -1.238  -1.198  -1.210  -1.177
6     I        -2.144  -2.101  -1.904  -2.128  -2.044  -1.766  -1.742  -1.693  -1.462
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -0.702  -0.708  -0.757  -0.675  -0.686  -0.844  -0.850  -0.854  -0.918
12    G        -0.807  -0.836  -0.766  -1.107  -1.148  -1.017  -1.017  -1.034  -0.930
13    V        -0.807  -0.812  -0.765  -1.011  -1.022  -0.893  -1.017  -1.021  -0.930
14    P         0.926   0.937   0.974   0.998   1.014   1.065   0.978   0.991   1.043
15    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    A        -0.702  -0.717  -0.760  -0.729  -0.754  -0.816  -0.850  -0.867  -0.921
17    S         0.926   0.937   0.974   0.872   0.889   0.952   0.978   0.991   1.043
18    L         0.223   0.320  -0.029   0.115   0.246  -0.257   0.179   0.321  -0.258
19    A        -1.602  -1.437  -1.569  -1.493  -1.228  -1.515  -1.420  -1.243  -1.327
20    G        -2.069  -2.003  -1.889  -2.041  -1.966  -1.739  -1.687  -1.622  -1.452
21    I        -0.244  -0.208  -0.135  -0.605  -0.540  -0.407  -0.621  -0.555  -0.451
22    K         0.926   0.937   0.974   0.913   0.932   0.989   0.978   0.991   1.043
23    H         0.223   0.160  -0.038   0.555   0.472   0.138   0.179   0.079  -0.275
24    I         0.926   0.937   0.974   0.901   0.924   0.977   0.978   0.991   1.043
25    I        -0.712  -0.724  -0.754  -0.915  -0.976  -1.018  -0.887  -0.925  -0.917
26    L         0.926   0.937   0.974   0.766   0.784   0.856   0.978   0.991   1.043
27    I        -0.244  -0.189  -0.130  -0.605  -0.505  -0.398  -0.621  -0.521  -0.442
28    L         0.926   0.937   0.974   0.766   0.784   0.856   0.978   0.991   1.043
29    S         0.926   0.937   0.974   0.872   0.889   0.952   0.978   0.991   1.043
30    G         0.926   0.937   0.974   0.777   0.790   0.865   0.978   0.991   1.043
31    K         0.926   0.937   0.974   0.913   0.932   0.989   0.978   0.991   1.043
32    G         0.926   0.937   0.974   0.777   0.790   0.865   0.978   0.991   1.043
33    G         0.926   0.937   0.974   0.777   0.790   0.865   0.978   0.991   1.043
34    V         0.926   0.937   0.974   0.816   0.824   0.901   0.978   0.991   1.043
35    G         0.926   0.937   0.974   0.777   0.790   0.865   0.978   0.991   1.043
36    K         0.926   0.937   0.974   0.913   0.932   0.989   0.978   0.991   1.043
37    S         0.926   0.937   0.974   0.872   0.889   0.952   0.978   0.991   1.043
38    S         0.926   0.937   0.974   0.872   0.889   0.952   0.978   0.991   1.043
39    V         0.926   0.937   0.974   0.816   0.824   0.901   0.978   0.991   1.043
40    T         0.926   0.937   0.974   0.974   0.986   1.044   0.978   0.991   1.043
41    T         0.926   0.937   0.974   0.974   0.986   1.044   0.978   0.991   1.043
42    Q         0.926   0.937   0.974   1.068   1.083   1.129   0.978   0.991   1.043
43    T        -0.712  -0.700  -0.749  -0.856  -0.902  -0.961  -0.887  -0.900  -0.910
44    A         0.926   0.937   0.974   1.046   1.047   1.109   0.978   0.991   1.043
45    L         0.926   0.937   0.974   0.766   0.784   0.856   0.978   0.991   1.043
46    T         0.223   0.097  -0.038   0.318   0.135  -0.108   0.179  -0.021  -0.274
47    L         0.926   0.937   0.974   0.766   0.784   0.856   0.978   0.991   1.043
48    C        -1.262  -1.330  -1.227  -1.194  -1.292  -1.156  -1.287  -1.336  -1.186
49    S        -1.730  -1.688  -1.595  -1.815  -1.762  -1.617  -1.553  -1.501  -1.350
50    M        -1.262  -1.343  -1.231  -1.164  -1.262  -1.076  -1.287  -1.351  -1.191
51    G         0.926   0.937   0.974   0.777   0.790   0.865   0.978   0.991   1.043
52    F        -1.262  -1.346  -1.228  -1.032  -1.137  -0.975  -1.287  -1.355  -1.189
53    K        -0.795  -0.850  -0.757  -0.891  -0.965  -0.824  -1.020  -1.064  -0.920
54    V         0.223   0.299  -0.029   0.177   0.269  -0.185   0.179   0.291  -0.258
55    G         0.926   0.937   0.974   0.777   0.790   0.865   0.978   0.991   1.043
56    V         0.926   0.937   0.974   0.816   0.824   0.901   0.978   0.991   1.043
57    L         0.926   0.937   0.974   0.766   0.784   0.856   0.978   0.991   1.043
58    D         0.926   0.937   0.974   0.981   0.995   1.050   0.978   0.991   1.043
59    I         0.223   0.097  -0.038   0.236   0.057  -0.193   0.179  -0.021  -0.274
60    D         0.926   0.937   0.974   0.981   0.995   1.050   0.978   0.991   1.043
61    L         0.926   0.937   0.974   0.766   0.784   0.856   0.978   0.991   1.043
62    T         0.926   0.937   0.974   0.974   0.986   1.044   0.978   0.991   1.043
63    G         0.926   0.937   0.974   0.777   0.790   0.865   0.978   0.991   1.043
64    P         0.926   0.937   0.974   0.996   1.012   1.064   0.978   0.991   1.043
65    S         0.926   0.937   0.974   0.872   0.889   0.952   0.978   0.991   1.043
66    L        -0.099  -0.182  -0.122  -0.382  -0.527  -0.422  -0.354  -0.506  -0.427
67    P         0.926   0.937   0.974   0.996   1.012   1.064   0.978   0.991   1.043
68    R         0.926   0.937   0.974   1.109   1.118   1.167   0.978   0.991   1.043
69    M         0.223   0.160  -0.038   0.499   0.414   0.092   0.179   0.079  -0.275
70    F         0.926   0.937   0.974   1.065   1.076   1.127   0.978   0.991   1.043
71    G         0.926   0.937   0.974   0.777   0.790   0.865   0.978   0.991   1.043
72    L        -1.390  -1.385  -1.241  -1.666  -1.616  -1.368  -1.420  -1.396  -1.201
73    E         0.926   0.937   0.974   0.951   0.973   1.023   0.978   0.991   1.043
74    N        -0.795  -0.726  -0.755  -0.819  -0.723  -0.738  -1.020  -0.934  -0.919
75    E        -1.051  -1.071  -1.198  -0.959  -0.985  -1.192  -1.020  -1.045  -1.156
76    S        -0.712  -0.765  -0.748  -0.700  -0.766  -0.789  -0.887  -0.937  -0.907
77    I        -0.099  -0.038  -0.101  -0.334  -0.233  -0.345  -0.354  -0.249  -0.388
78    Y        -0.712  -0.741  -0.741  -0.474  -0.511  -0.544  -0.887  -0.902  -0.897
79    Q         0.926   0.937   0.974   1.068   1.083   1.129   0.978   0.991   1.043
80    G        -0.712  -0.711  -0.751  -0.830  -0.842  -0.893  -0.887  -0.898  -0.912
81    P        -1.262  -1.182  -1.215  -1.294  -1.194  -1.184  -1.287  -1.206  -1.176
82    E        -2.069  -2.014  -1.891  -1.918  -1.876  -1.680  -1.687  -1.630  -1.454
83    G         0.926   0.937   0.974   0.777   0.790   0.865   0.978   0.991   1.043
84    W         0.926   0.937   0.974   1.184   1.197   1.234   0.978   0.991   1.043
85    Q        -1.602  -1.595  -1.585  -1.595  -1.623  -1.544  -1.420  -1.407  -1.341
86    P         0.926   0.937   0.974   0.996   1.012   1.064   0.978   0.991   1.043
87    V        -0.099  -0.134  -0.115  -0.334  -0.403  -0.372  -0.354  -0.420  -0.415
88    K        -1.203  -1.240  -1.228  -1.225  -1.290  -1.263  -1.198  -1.240  -1.187
89    V         0.926   0.937   0.974   0.813   0.818   0.898   0.978   0.991   1.043
90    E        -1.262  -1.289  -1.227  -1.046  -1.056  -0.990  -1.287  -1.299  -1.187
91    T        -0.712  -0.741  -0.741  -0.691  -0.719  -0.734  -0.887  -0.902  -0.897
92    N        -1.051  -1.174  -1.206  -0.785  -0.971  -1.050  -1.020  -1.160  -1.164
93    S        -1.730  -1.742  -1.594  -1.804  -1.807  -1.540  -1.553  -1.548  -1.349
94    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
95    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
96    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
97    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
98    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
99    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
100   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
101   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
102   T        -2.069  -2.070  -1.900  -1.998  -2.055  -1.812  -1.687  -1.672  -1.459
103   G         0.223   0.160  -0.038   0.162   0.082  -0.176   0.179   0.079  -0.275
104   S        -1.262  -1.220  -1.224  -1.247  -1.196  -1.208  -1.287  -1.242  -1.184
105   L         0.926   0.937   0.974   0.766   0.784   0.856   0.978   0.991   1.043
106   S        -1.262  -1.312  -1.227  -1.210  -1.255  -1.113  -1.287  -1.327  -1.187
107   V        -0.244  -0.238  -0.138  -0.702  -0.696  -0.503  -0.621  -0.612  -0.457
108   I        -0.439  -0.344  -0.700  -0.185  -0.050  -0.669  -0.488  -0.357  -0.841
109   S         0.926   0.937   0.974   0.872   0.889   0.952   0.978   0.991   1.043
110   L         0.926   0.937   0.974   0.766   0.784   0.856   0.978   0.991   1.043
111   G         0.926   0.937   0.974   0.777   0.790   0.865   0.978   0.991   1.043
112   F         0.926   0.937   0.974   1.065   1.076   1.127   0.978   0.991   1.043
113   L         0.926   0.937   0.974   0.766   0.784   0.856   0.978   0.991   1.043
114   L         0.223   0.299  -0.029   0.115   0.220  -0.257   0.179   0.291  -0.258
115   G        -1.051  -1.174  -1.206  -1.097  -1.285  -1.309  -1.020  -1.160  -1.164
116   D        -1.262  -1.288  -1.222  -1.284  -1.339  -1.208  -1.287  -1.307  -1.183
117   R         0.926   0.937   0.974   1.109   1.118   1.167   0.978   0.991   1.043
118   G         0.223   0.299  -0.029   0.154   0.250  -0.181   0.179   0.291  -0.258
119   N        -1.262  -1.205  -1.221  -1.193  -1.129  -1.150  -1.287  -1.233  -1.182
120   S         0.223   0.097  -0.038   0.246   0.076  -0.122   0.179  -0.021  -0.274
121   V         0.926   0.937   0.974   0.816   0.824   0.901   0.978   0.991   1.043
122   I         0.223   0.273  -0.033   0.165   0.228  -0.221   0.179   0.253  -0.265
123   W         0.926   0.937   0.974   1.184   1.197   1.234   0.978   0.991   1.043
124   R         0.926   0.937   0.974   1.109   1.118   1.167   0.978   0.991   1.043
125   G         0.926   0.937   0.974   0.777   0.790   0.865   0.978   0.991   1.043
126   P         0.926   0.937   0.974   0.996   1.012   1.064   0.978   0.991   1.043
127   K         0.223   0.160  -0.038   0.298   0.222  -0.063   0.179   0.079  -0.275
128   K         0.926   0.937   0.974   0.913   0.932   0.989   0.978   0.991   1.043
129   T         0.223   0.257  -0.037   0.318   0.364  -0.105   0.179   0.230  -0.272
130   S        -0.099  -0.038  -0.101  -0.125  -0.029  -0.176  -0.354  -0.249  -0.388
131   M         0.926   0.937   0.974   1.124   1.137   1.180   0.978   0.991   1.043
132   I         0.223   0.097  -0.038   0.236   0.057  -0.193   0.179  -0.021  -0.274
133   K        -0.244  -0.200  -0.133  -0.353  -0.263  -0.185  -0.621  -0.541  -0.448
134   Q         0.926   0.937   0.974   1.068   1.083   1.129   0.978   0.991   1.043
135   F         0.926   0.937   0.974   1.065   1.076   1.127   0.978   0.991   1.043
136   I        -0.244  -0.231  -0.136  -0.618  -0.590  -0.432  -0.621  -0.599  -0.453
137   S        -0.712  -0.788  -0.753  -0.796  -0.914  -0.834  -0.887  -0.984  -0.915
138   D         0.926   0.937   0.974   0.981   0.995   1.050   0.978   0.991   1.043
139   V         0.926   0.937   0.974   0.816   0.824   0.901   0.978   0.991   1.043
140   A        -1.602  -1.595  -1.585  -1.532  -1.529  -1.460  -1.420  -1.407  -1.341
141   W         0.926   0.937   0.974   1.184   1.197   1.234   0.978   0.991   1.043
142   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
143   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
144   G         0.223   0.097  -0.038   0.140  -0.034  -0.229   0.179  -0.021  -0.274
145   E        -0.439  -0.328  -0.695  -0.330  -0.169  -0.742  -0.488  -0.337  -0.834
146   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
147   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
148   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
149   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
150   L         0.223   0.097  -0.038   0.128  -0.042  -0.241   0.179  -0.021  -0.274
151   D         0.926   0.937   0.974   0.981   0.995   1.050   0.978   0.991   1.043
152   Y         0.926   0.937   0.974   1.155   1.170   1.208   0.978   0.991   1.043
153   L         0.926   0.937   0.974   0.766   0.784   0.856   0.978   0.991   1.043
154   L         0.223   0.257  -0.037   0.115   0.167  -0.270   0.179   0.230  -0.272
155   I         0.926   0.937   0.974   0.901   0.924   0.977   0.978   0.991   1.043
156   D         0.926   0.937   0.974   0.981   0.995   1.050   0.978   0.991   1.043
157   T         0.926   0.937   0.974   0.974   0.986   1.044   0.978   0.991   1.043
158   P         0.926   0.937   0.974   0.996   1.012   1.064   0.978   0.991   1.043
159   P         0.926   0.937   0.974   0.996   1.012   1.064   0.978   0.991   1.043
160   G         0.926   0.937   0.974   0.777   0.790   0.865   0.978   0.991   1.043
161   T         0.926   0.937   0.974   0.974   0.986   1.044   0.978   0.991   1.043
162   S         0.926   0.937   0.974   0.872   0.889   0.952   0.978   0.991   1.043
163   D         0.926   0.937   0.974   0.981   0.995   1.050   0.978   0.991   1.043
164   E         0.926   0.937   0.974   0.951   0.973   1.023   0.978   0.991   1.043
165   H         0.926   0.937   0.974   1.182   1.194   1.232   0.978   0.991   1.043
166   I         0.926   0.937   0.974   0.901   0.924   0.977   0.978   0.991   1.043
167   S        -0.099  -0.005  -0.090  -0.223  -0.076  -0.208  -0.354  -0.192  -0.369
168   I         0.223   0.097  -0.038   0.228   0.048  -0.212   0.179  -0.021  -0.274
169   A         0.926   0.937   0.974   1.046   1.047   1.109   0.978   0.991   1.043
170   E         0.926   0.937   0.974   0.951   0.973   1.023   0.978   0.991   1.043
171   E         0.223   0.097  -0.038   0.327   0.168  -0.050   0.179  -0.021  -0.274
172   L         0.926   0.937   0.974   0.766   0.784   0.856   0.978   0.991   1.043
173   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
174   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
175   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
176   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
177   R         0.926   0.937   0.974   1.109   1.118   1.167   0.978   0.991   1.043
178   Y        -1.262  -1.303  -1.228  -0.973  -1.048  -0.935  -1.287  -1.320  -1.189
179   S        -1.602  -1.649  -1.590  -1.413  -1.524  -1.447  -1.420  -1.459  -1.345
180   K        -1.602  -1.665  -1.587  -1.329  -1.426  -1.339  -1.420  -1.473  -1.342
181   P        -0.439  -0.610  -0.713  -0.288  -0.551  -0.745  -0.488  -0.720  -0.858
182   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
183   D        -0.439  -0.610  -0.713  -0.307  -0.567  -0.766  -0.488  -0.720  -0.858
184   G         0.926   0.937   0.974   0.777   0.790   0.865   0.978   0.991   1.043
185   G         0.223   0.273  -0.033   0.375   0.431  -0.073   0.179   0.253  -0.265
186   I        -0.099  -0.182  -0.122  -0.285  -0.452  -0.368  -0.354  -0.506  -0.427
187   V        -0.244  -0.238  -0.138  -0.587  -0.581  -0.407  -0.621  -0.612  -0.457
188   V         0.926   0.937   0.974   0.816   0.824   0.901   0.978   0.991   1.043
189   T         0.926   0.937   0.974   0.974   0.986   1.044   0.978   0.991   1.043
190   T         0.926   0.937   0.974   0.974   0.986   1.044   0.978   0.991   1.043
191   P         0.926   0.937   0.974   0.996   1.012   1.064   0.978   0.991   1.043
192   Q         0.926   0.937   0.974   1.068   1.083   1.129   0.978   0.991   1.043
193   S        -1.262  -1.264  -1.219  -1.360  -1.357  -1.256  -1.287  -1.270  -1.178
194   V         0.926   0.937   0.974   0.816   0.824   0.901   0.978   0.991   1.043
195   A         0.926   0.937   0.974   1.046   1.047   1.109   0.978   0.991   1.043
196   T         0.223   0.160  -0.038   0.301   0.208  -0.150   0.179   0.079  -0.275
197   A         0.926   0.937   0.974   1.046   1.047   1.109   0.978   0.991   1.043
198   D         0.926   0.937   0.974   0.981   0.995   1.050   0.978   0.991   1.043
199   V         0.926   0.937   0.974   0.816   0.824   0.901   0.978   0.991   1.043
200   K        -0.099  -0.038  -0.101  -0.049   0.053  -0.106  -0.354  -0.249  -0.388
201   K         0.926   0.937   0.974   0.913   0.932   0.989   0.978   0.991   1.043
202   E         0.926   0.937   0.974   0.951   0.973   1.023   0.978   0.991   1.043
203   I        -0.099  -0.182  -0.122  -0.304  -0.472  -0.396  -0.354  -0.506  -0.427
204   N         0.223   0.160  -0.038   0.407   0.326  -0.033   0.179   0.079  -0.275
205   F         0.926   0.937   0.974   1.065   1.076   1.127   0.978   0.991   1.043
206   C         0.926   0.937   0.974   1.143   1.154   1.197   0.978   0.991   1.043
207   K        -0.439  -0.502  -0.703  -0.321  -0.418  -0.693  -0.488  -0.580  -0.844
208   K         0.926   0.937   0.974   0.913   0.932   0.989   0.978   0.991   1.043
209   V        -0.439  -0.610  -0.713  -0.460  -0.715  -0.870  -0.488  -0.720  -0.858
210   D        -0.439  -0.459  -0.703  -0.237  -0.269  -0.705  -0.488  -0.515  -0.845
211   L        -0.712  -0.765  -0.748  -0.751  -0.818  -0.849  -0.887  -0.937  -0.907
212   K        -2.069  -1.987  -1.891  -1.751  -1.627  -1.519  -1.687  -1.606  -1.454
213   I        -0.099  -0.130  -0.118  -0.285  -0.344  -0.358  -0.354  -0.411  -0.419
214   L         0.926   0.937   0.974   0.766   0.784   0.856   0.978   0.991   1.043
215   G         0.926   0.937   0.974   0.777   0.790   0.865   0.978   0.991   1.043
216   I        -0.244  -0.223  -0.136  -0.605  -0.568  -0.409  -0.621  -0.583  -0.454
217   I        -0.244  -0.231  -0.136  -0.587  -0.564  -0.401  -0.621  -0.599  -0.453
218   E         0.926   0.937   0.974   0.951   0.973   1.023   0.978   0.991   1.043
219   N         0.926   0.937   0.974   1.063   1.085   1.124   0.978   0.991   1.043
220   M         0.926   0.937   0.974   1.124   1.137   1.180   0.978   0.991   1.043
221   S         0.223   0.097  -0.038   0.263   0.103  -0.082   0.179  -0.021  -0.274
222   G         0.926   0.937   0.974   0.777   0.790   0.865   0.978   0.991   1.043
223   F         0.223   0.160  -0.038   0.456   0.374   0.080   0.179   0.079  -0.275
224   V        -0.244  -0.194  -0.130  -0.605  -0.513  -0.399  -0.621  -0.529  -0.442
225   C         0.926   0.937   0.974   1.143   1.154   1.197   0.978   0.991   1.043
226   P         0.926   0.937   0.974   0.996   1.012   1.064   0.978   0.991   1.043
227   H        -0.439  -0.502  -0.703  -0.035  -0.132  -0.443  -0.488  -0.580  -0.844
228   C         0.926   0.937   0.974   1.143   1.154   1.197   0.978   0.991   1.043
229   A        -0.712  -0.631  -0.746  -0.785  -0.670  -0.811  -0.887  -0.775  -0.905
230   E         0.926   0.937   0.974   0.951   0.973   1.023   0.978   0.991   1.043
231   C         0.926   0.937   0.974   1.143   1.154   1.197   0.978   0.991   1.043
232   T         0.223   0.160  -0.038   0.351   0.268  -0.030   0.179   0.079  -0.275
233   N         0.223   0.257  -0.037   0.425   0.478   0.012   0.179   0.230  -0.272
234   I         0.926   0.937   0.974   0.901   0.924   0.977   0.978   0.991   1.043
235   F         0.926   0.937   0.974   1.065   1.076   1.127   0.978   0.991   1.043
236   S        -0.439  -0.492  -0.699  -0.399  -0.464  -0.793  -0.488  -0.567  -0.839
237   S        -0.712  -0.691  -0.748  -0.815  -0.787  -0.831  -0.887  -0.859  -0.908
238   G         0.926   0.937   0.974   0.777   0.790   0.865   0.978   0.991   1.043
239   G         0.926   0.937   0.974   0.777   0.790   0.865   0.978   0.991   1.043
240   G         0.926   0.937   0.974   0.777   0.790   0.865   0.978   0.991   1.043
241   K        -0.795  -0.749  -0.757  -0.926  -0.840  -0.812  -1.020  -0.954  -0.921
242   R        -2.408  -2.355  -2.152  -2.212  -2.155  -1.842  -1.820  -1.766  -1.534
243   L         0.223   0.097  -0.038   0.155  -0.004  -0.177   0.179  -0.021  -0.274
244   S        -0.244  -0.189  -0.130  -0.430  -0.324  -0.245  -0.621  -0.521  -0.442
245   E        -1.262  -1.312  -1.227  -1.298  -1.352  -1.229  -1.287  -1.327  -1.187
246   Q        -1.051  -1.074  -1.192  -0.816  -0.856  -1.083  -1.020  -1.048  -1.149
247   F        -0.923  -0.878  -0.781  -0.998  -0.900  -0.774  -1.154  -1.089  -0.949
248   S        -1.730  -1.759  -1.595  -1.701  -1.766  -1.526  -1.553  -1.560  -1.349
249   V        -0.712  -0.693  -0.740  -0.927  -0.862  -0.911  -0.887  -0.839  -0.896
250   P        -1.602  -1.615  -1.584  -1.371  -1.398  -1.351  -1.420  -1.430  -1.340
251   Y        -0.244  -0.245  -0.139  -0.226  -0.241  -0.080  -0.621  -0.625  -0.460
252   L         0.926   0.937   0.974   0.766   0.784   0.856   0.978   0.991   1.043
253   G         0.926   0.937   0.974   0.777   0.790   0.865   0.978   0.991   1.043
254   N        -0.439  -0.610  -0.713  -0.175  -0.412  -0.597  -0.488  -0.720  -0.858
255   V        -0.244  -0.202  -0.135  -0.605  -0.529  -0.407  -0.621  -0.544  -0.451
256   P         0.926   0.937   0.974   0.996   1.012   1.064   0.978   0.991   1.043
257   I         0.926   0.937   0.974   0.901   0.924   0.977   0.978   0.991   1.043
258   D         0.926   0.937   0.974   0.981   0.995   1.050   0.978   0.991   1.043
259   P         0.926   0.937   0.974   0.996   1.012   1.064   0.978   0.991   1.043
260   K        -1.262  -1.206  -1.219  -1.268  -1.182  -1.190  -1.287  -1.226  -1.180
261   F         0.926   0.937   0.974   1.065   1.076   1.127   0.978   0.991   1.043
262   V         0.223   0.097  -0.038   0.142  -0.051  -0.286   0.179  -0.021  -0.274
263   E        -1.051  -1.153  -1.203  -0.996  -1.184  -1.301  -1.020  -1.139  -1.161
264   M        -0.244  -0.226  -0.137  -0.502  -0.471  -0.300  -0.621  -0.589  -0.455
265   I        -0.244  -0.218  -0.133  -0.587  -0.534  -0.395  -0.621  -0.575  -0.449
266   E         0.926   0.937   0.974   0.951   0.973   1.023   0.978   0.991   1.043
267   N        -1.602  -1.558  -1.579  -1.395  -1.329  -1.413  -1.420  -1.374  -1.336
268   Q        -0.439  -0.610  -0.713  -0.220  -0.490  -0.695  -0.488  -0.720  -0.858
269   V        -1.602  -1.446  -1.573  -1.515  -1.280  -1.477  -1.420  -1.253  -1.330
270   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
271   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
272   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
273   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
274   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
275   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
276   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
277   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
278   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
279   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
280   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
281   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
282   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
283   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
284   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
285   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
286   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
287   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
288   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
289   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
290   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
291   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
292   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
293   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
294   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
295   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
296   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
297   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
298   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
299   S        -1.748  -1.644  -1.597  -1.820  -1.637  -1.592  -1.561  -1.449  -1.350
300   S        -1.748  -1.647  -1.593  -1.572  -1.426  -1.341  -1.561  -1.452  -1.348
301   K        -1.352  -1.368  -1.236  -1.471  -1.512  -1.279  -1.379  -1.382  -1.196
302   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
303   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
304   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
305   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
306   K        -1.262  -1.312  -1.227  -1.441  -1.528  -1.378  -1.287  -1.327  -1.187
307   T        -1.730  -1.764  -1.603  -1.755  -1.792  -1.558  -1.553  -1.564  -1.355
308   L         0.926   0.937   0.974   0.766   0.784   0.856   0.978   0.991   1.043
309   V        -0.439  -0.417  -0.697  -0.441  -0.414  -0.806  -0.488  -0.462  -0.837
310   E        -0.712  -0.767  -0.746  -0.696  -0.740  -0.708  -0.887  -0.939  -0.905
311   M        -1.051  -1.163  -1.201  -1.085  -1.257  -1.271  -1.020  -1.149  -1.159
312   Y         0.926   0.937   0.974   1.155   1.170   1.208   0.978   0.991   1.043
313   R        -1.730  -1.688  -1.595  -1.723  -1.675  -1.513  -1.553  -1.501  -1.350
314   E        -0.712  -0.672  -0.750  -0.744  -0.691  -0.817  -0.887  -0.841  -0.911
315   S        -0.795  -0.820  -0.760  -0.837  -0.854  -0.759  -1.020  -1.033  -0.925
316   S        -1.262  -1.237  -1.221  -1.394  -1.333  -1.323  -1.287  -1.239  -1.181
317   L         0.223   0.160  -0.038   0.155   0.080  -0.178   0.179   0.079  -0.275
318   C        -1.390  -1.330  -1.241  -1.278  -1.190  -1.030  -1.420  -1.346  -1.201
319   P        -1.051  -1.027  -1.188  -0.965  -0.928  -1.261  -1.020  -0.989  -1.145
320   I         0.926   0.937   0.974   0.901   0.924   0.977   0.978   0.991   1.043
321   F        -1.051  -0.875  -1.182  -0.770  -0.524  -0.989  -1.020  -0.806  -1.139
322   E        -1.730  -1.671  -1.591  -1.758  -1.669  -1.528  -1.553  -1.490  -1.346
323   E        -0.923  -0.907  -0.786  -1.257  -1.225  -1.011  -1.154  -1.128  -0.956
324   I         0.926   0.937   0.974   0.901   0.924   0.977   0.978   0.991   1.043
325   M        -1.730  -1.764  -1.603  -1.673  -1.702  -1.471  -1.553  -1.564  -1.355
326   K        -0.712  -0.765  -0.748  -0.731  -0.791  -0.777  -0.887  -0.937  -0.907
327   K        -0.439  -0.528  -0.710  -0.329  -0.454  -0.720  -0.488  -0.612  -0.854
328   L        -1.051  -0.998  -1.184  -1.093  -1.017  -1.306  -1.020  -0.956  -1.141
329   R        -1.602  -1.649  -1.590  -1.551  -1.623  -1.460  -1.420  -1.459  -1.345
330   K        -1.730  -1.629  -1.591  -1.731  -1.585  -1.497  -1.553  -1.451  -1.347
331   Q        -1.352  -1.293  -1.234  -1.439  -1.356  -1.273  -1.379  -1.310  -1.194
332   D        -1.748  -1.649  -1.596  -1.679  -1.532  -1.444  -1.561  -1.454  -1.350
333   T        -2.144  -2.101  -1.904  -2.086  -1.993  -1.728  -1.742  -1.693  -1.462
334   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
335   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
336   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
337   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
339   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
340   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
341   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
342   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
343   Q        -2.069  -2.070  -1.900  -1.931  -1.929  -1.697  -1.687  -1.672  -1.459
344   P        -2.069  -2.049  -1.898  -1.969  -1.973  -1.734  -1.687  -1.658  -1.458
345   Q        -1.262  -1.237  -1.221  -1.107  -1.065  -1.064  -1.287  -1.239  -1.181
346   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
347   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
348   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
349   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
350   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
351   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
352   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
353   K        -1.602  -1.426  -1.570  -1.376  -1.099  -1.374  -1.420  -1.231  -1.328
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P40558
Output conservation file - output/P40558
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
