1     M         1.998   2.010   2.115   2.258   2.271   2.445   2.256   2.274   2.458
2     E        -0.316  -0.347  -0.294  -0.399  -0.456  -0.396  -0.504  -0.543  -0.477
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    L        -0.316  -0.347  -0.294  -0.370  -0.442  -0.397  -0.504  -0.543  -0.477
29    A        -0.312  -0.265  -0.264  -0.425  -0.363  -0.352  -0.513  -0.462  -0.446
30    N        -0.160  -0.151  -0.183  -0.174  -0.161  -0.229  -0.300  -0.289  -0.333
31    V         0.241   0.231   0.262  -0.172  -0.188  -0.144  -0.087  -0.104  -0.068
32    K        -0.713  -0.744  -0.690  -0.663  -0.708  -0.624  -0.726  -0.757  -0.685
33    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    I         0.241   0.241   0.272  -0.097  -0.069  -0.055  -0.087  -0.077  -0.047
39    D         0.892   0.869   0.933   0.688   0.642   0.731   0.552   0.495   0.561
40    P        -0.312  -0.301  -0.269  -0.393  -0.378  -0.328  -0.513  -0.502  -0.451
41    S        -0.312  -0.289  -0.263  -0.536  -0.499  -0.479  -0.513  -0.487  -0.445
42    L         0.241   0.241   0.272  -0.076  -0.075  -0.022  -0.087  -0.077  -0.047
43    T         0.241   0.264   0.276   0.257   0.297   0.315  -0.087  -0.045  -0.041
44    S         0.241   0.217   0.258   0.112   0.068   0.121  -0.087  -0.124  -0.074
45    R        -0.713  -0.694  -0.671  -0.710  -0.676  -0.653  -0.726  -0.706  -0.666
46    I         0.241   0.241   0.272   0.235   0.237   0.289  -0.087  -0.077  -0.047
47    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
48    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
49    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
50    S        -1.114  -1.108  -1.039  -1.182  -1.171  -1.071  -0.939  -0.932  -0.844
51    Q        -0.713  -0.721  -0.671  -0.822  -0.835  -0.763  -0.726  -0.734  -0.666
52    I        -0.713  -0.744  -0.690  -0.609  -0.671  -0.605  -0.726  -0.757  -0.685
53    D        -1.114  -1.108  -1.039  -1.094  -1.076  -0.981  -0.939  -0.932  -0.844
54    S         0.124   0.132   0.200   0.017   0.034   0.136  -0.248  -0.237  -0.155
55    F         0.133   0.100  -0.041   0.057   0.020  -0.182   0.100   0.054  -0.142
56    K        -1.313  -1.314  -1.274  -1.094  -1.093  -1.027  -0.979  -0.978  -0.913
57    L        -0.109  -0.096  -0.164  -0.005   0.013  -0.095  -0.260  -0.245  -0.321
58    S        -1.313  -1.292  -1.273  -1.134  -1.088  -1.066  -0.979  -0.960  -0.911
59    E         0.849   0.843   0.915   0.726   0.711   0.799   0.459   0.440   0.520
60    L         1.343   1.313   1.234   1.178   1.145   1.036   1.417   1.363   1.189
61    M        -0.296  -0.305  -0.267  -0.311  -0.320  -0.259  -0.499  -0.510  -0.452
62    V        -1.313  -1.296  -1.269  -1.176  -1.162  -1.120  -0.979  -0.963  -0.908
63    L        -0.597  -0.542  -0.604  -0.621  -0.550  -0.623  -0.619  -0.566  -0.603
64    K         1.343   1.317   1.231   1.513   1.477   1.368   1.417   1.370   1.184
65    T        -0.597  -0.621  -0.604  -0.630  -0.667  -0.630  -0.619  -0.641  -0.603
66    D        -0.109  -0.127  -0.173  -0.140  -0.168  -0.254  -0.260  -0.284  -0.335
67    I         0.720   0.658   0.528   0.804   0.720   0.488   0.699   0.602   0.378
68    E         1.343   1.317   1.231   1.453   1.421   1.307   1.417   1.370   1.184
69    T        -1.313  -1.325  -1.276  -1.226  -1.253  -1.175  -0.979  -0.986  -0.914
70    Q        -0.183  -0.200  -0.189  -0.187  -0.209  -0.184  -0.380  -0.395  -0.365
71    L         0.720   0.700   0.533   0.575   0.554   0.299   0.699   0.667   0.387
72    E        -1.012  -1.023  -0.986  -0.999  -1.018  -0.960  -0.859  -0.866  -0.803
73    A        -0.898  -0.862  -0.919  -0.820  -0.754  -0.884  -0.739  -0.701  -0.737
74    Y         0.133   0.108  -0.049   0.130   0.105  -0.082   0.100   0.065  -0.152
75    F        -0.410  -0.442  -0.533  -0.093  -0.133  -0.311  -0.380  -0.416  -0.513
76    S        -0.109  -0.110  -0.171  -0.158  -0.165  -0.252  -0.260  -0.263  -0.330
77    V         0.133   0.189  -0.031   0.181   0.260  -0.100   0.100   0.174  -0.128
78    L         1.998   2.010   2.115   1.768   1.789   1.945   2.256   2.274   2.458
79    E        -1.313  -1.326  -1.273  -1.314  -1.342  -1.274  -0.979  -0.987  -0.911
80    Q        -1.012  -1.006  -0.980  -0.884  -0.886  -0.815  -0.859  -0.852  -0.798
81    Q        -0.597  -0.553  -0.595  -0.380  -0.309  -0.381  -0.619  -0.570  -0.594
82    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
83    G        -0.296  -0.299  -0.257  -0.371  -0.383  -0.308  -0.499  -0.502  -0.441
84    I        -0.109  -0.064  -0.137  -0.155  -0.083  -0.195  -0.260  -0.191  -0.282
85    G         0.133   0.100  -0.041   0.233   0.181  -0.027   0.100   0.054  -0.142
86    M         1.998   2.010   2.115   2.258   2.271   2.445   2.256   2.274   2.458
87    D        -0.296  -0.283  -0.257  -0.460  -0.455  -0.397  -0.499  -0.491  -0.442
88    S         1.021   1.031   1.023   0.988   0.998   0.956   0.818   0.832   0.757
89    A         0.720   0.712   0.532   0.953   0.946   0.683   0.699   0.685   0.386
90    L         1.998   2.010   2.115   1.768   1.789   1.945   2.256   2.274   2.458
91    V         0.338   0.342   0.318  -0.015  -0.004  -0.048   0.065   0.080   0.019
92    T         1.998   2.010   2.115   2.076   2.086   2.260   2.256   2.274   2.458
93    P        -0.898  -0.913  -0.920  -0.716  -0.739  -0.770  -0.739  -0.753  -0.738
94    D         1.343   1.313   1.234   1.379   1.339   1.235   1.417   1.363   1.189
95    G         1.998   2.010   2.115   2.093   2.105   2.277   2.256   2.274   2.458
96    Y         1.021   1.053   1.017   1.232   1.281   1.220   0.818   0.876   0.744
97    P         1.998   2.010   2.115   2.130   2.150   2.316   2.256   2.274   2.458
98    R         1.998   2.010   2.115   2.064   2.078   2.248   2.256   2.274   2.458
99    S        -0.109  -0.139  -0.156  -0.131  -0.167  -0.200  -0.260  -0.289  -0.312
100   D         1.998   2.010   2.115   1.973   1.987   2.155   2.256   2.274   2.458
101   V         0.434   0.443   0.375   0.293   0.317   0.157   0.219   0.233   0.113
102   D         1.998   2.010   2.115   1.973   1.987   2.155   2.256   2.274   2.458
103   V         1.343   1.313   1.234   1.361   1.310   1.187   1.417   1.363   1.189
104   L        -0.898  -0.926  -0.944  -0.726  -0.767  -0.783  -0.739  -0.765  -0.761
105   Q        -0.109  -0.073  -0.156  -0.015   0.038  -0.092  -0.260  -0.215  -0.312
106   V         1.021   1.031   1.023   0.946   0.963   0.913   0.818   0.832   0.757
107   T         1.343   1.349   1.234   1.475   1.481   1.335   1.417   1.425   1.190
108   M        -0.597  -0.617  -0.620  -0.671  -0.691  -0.648  -0.619  -0.638  -0.620
109   I        -0.597  -0.574  -0.603  -0.665  -0.621  -0.693  -0.619  -0.598  -0.602
110   R         1.343   1.313   1.234   1.479   1.439   1.342   1.417   1.363   1.189
111   K        -1.313  -1.292  -1.271  -1.034  -0.993  -0.981  -0.979  -0.960  -0.910
112   N        -0.711  -0.722  -0.665  -0.712  -0.728  -0.634  -0.739  -0.745  -0.667
113   V         0.849   0.847   0.920   0.613   0.605   0.698   0.459   0.448   0.533
114   N         0.849   0.847   0.920   0.635   0.628   0.723   0.459   0.448   0.533
115   M        -0.597  -0.627  -0.621  -0.412  -0.456  -0.428  -0.619  -0.647  -0.620
116   L         1.998   2.010   2.115   1.768   1.789   1.945   2.256   2.274   2.458
117   K         0.720   0.691   0.527   0.893   0.853   0.620   0.699   0.653   0.378
118   N         1.998   2.010   2.115   2.035   2.043   2.218   2.256   2.274   2.458
119   D         1.998   2.010   2.115   1.973   1.987   2.155   2.256   2.274   2.458
120   L        -0.898  -0.870  -0.931  -0.925  -0.871  -0.944  -0.739  -0.710  -0.748
121   N        -0.597  -0.606  -0.610  -0.563  -0.578  -0.587  -0.619  -0.625  -0.610
122   H        -1.012  -1.020  -0.982  -0.949  -0.950  -0.904  -0.859  -0.863  -0.800
123   L         0.118   0.111   0.190  -0.347  -0.359  -0.248  -0.260  -0.270  -0.170
124   L        -1.012  -1.010  -0.978  -0.819  -0.812  -0.764  -0.859  -0.855  -0.797
125   Q        -1.313  -1.307  -1.273  -1.112  -1.115  -1.038  -0.979  -0.973  -0.912
126   R        -0.296  -0.320  -0.265  -0.581  -0.598  -0.516  -0.499  -0.525  -0.450
127   S        -0.109  -0.142  -0.170  -0.398  -0.439  -0.494  -0.260  -0.301  -0.330
128   H        -0.109  -0.070  -0.152  -0.023   0.035  -0.081  -0.260  -0.212  -0.306
129   V        -1.012  -1.016  -0.982  -0.877  -0.876  -0.826  -0.859  -0.861  -0.800
130   L        -0.711  -0.693  -0.663  -0.915  -0.903  -0.837  -0.739  -0.722  -0.665
131   L         0.720   0.745   0.544   0.615   0.646   0.381   0.699   0.733   0.404
132   N        -1.614  -1.610  -1.545  -1.277  -1.254  -1.168  -1.098  -1.093  -1.009
133   Q        -1.012  -1.036  -0.976  -0.991  -1.031  -0.948  -0.859  -0.876  -0.795
134   H        -0.109  -0.073  -0.156   0.073   0.125  -0.011  -0.260  -0.215  -0.312
135   F         1.343   1.317   1.231   1.678   1.649   1.563   1.417   1.370   1.184
136   D        -1.012  -1.024  -0.978  -0.986  -1.003  -0.939  -0.859  -0.866  -0.797
137   N        -0.597  -0.549  -0.594  -0.581  -0.521  -0.565  -0.619  -0.573  -0.593
138   M        -1.012  -1.032  -0.981  -0.870  -0.897  -0.818  -0.859  -0.872  -0.799
139   N        -0.711  -0.692  -0.666  -0.737  -0.716  -0.659  -0.739  -0.722  -0.667
140   V        -1.012  -0.997  -0.977  -0.975  -0.952  -0.925  -0.859  -0.844  -0.795
141   K        -0.711  -0.708  -0.664  -0.771  -0.753  -0.687  -0.739  -0.733  -0.665
142   S        -0.597  -0.593  -0.609  -0.630  -0.628  -0.649  -0.619  -0.614  -0.608
143   N        -1.313  -1.297  -1.268  -1.296  -1.267  -1.246  -0.979  -0.964  -0.907
144   Q        -1.012  -1.025  -0.980  -1.051  -1.062  -1.007  -0.859  -0.867  -0.798
145   D        -1.012  -1.012  -0.979  -1.025  -1.037  -0.984  -0.859  -0.857  -0.797
146   A        -0.597  -0.579  -0.607  -0.540  -0.518  -0.556  -0.619  -0.600  -0.605
147   -        -0.316  -0.321  -0.270  -0.312  -0.320  -0.237  -0.504  -0.510  -0.447
148   -        -0.797  -0.794  -0.718  -0.848  -0.839  -0.729  -0.811  -0.806  -0.712
149   -        -0.316  -0.321  -0.270  -0.273  -0.279  -0.198  -0.504  -0.510  -0.447
150   -        -0.316  -0.305  -0.267  -0.419  -0.408  -0.356  -0.504  -0.491  -0.444
151   -        -0.316  -0.313  -0.267  -0.701  -0.697  -0.636  -0.504  -0.500  -0.443
152   -        -0.797  -0.794  -0.718  -0.860  -0.857  -0.742  -0.811  -0.806  -0.712
153   -        -0.797  -0.794  -0.718  -0.762  -0.755  -0.642  -0.811  -0.806  -0.712
154   -        -0.316  -0.297  -0.267  -0.423  -0.392  -0.363  -0.504  -0.480  -0.443
155   -        -0.797  -0.794  -0.718  -0.865  -0.864  -0.747  -0.811  -0.806  -0.712
156   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
157   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
158   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
159   -        -0.316  -0.297  -0.260  -0.553  -0.515  -0.490  -0.504  -0.479  -0.434
160   -        -0.160  -0.163  -0.184  -0.040  -0.045  -0.085  -0.300  -0.304  -0.335
161   -        -0.350  -0.346  -0.287  -0.512  -0.504  -0.418  -0.560  -0.555  -0.475
162   R        -1.313  -1.342  -1.288  -1.194  -1.242  -1.160  -0.979  -0.999  -0.923
163   R        -1.313  -1.292  -1.271  -1.168  -1.142  -1.108  -0.979  -0.960  -0.910
164   N        -0.898  -0.889  -0.931  -0.787  -0.776  -0.851  -0.739  -0.729  -0.748
165   N        -1.614  -1.610  -1.545  -1.383  -1.384  -1.276  -1.098  -1.093  -1.009
166   D        -0.183  -0.187  -0.192  -0.279  -0.294  -0.291  -0.380  -0.382  -0.368
167   D        -1.012  -1.005  -0.978  -1.132  -1.120  -1.069  -0.859  -0.851  -0.796
168   Q        -1.313  -1.296  -1.269  -1.212  -1.186  -1.141  -0.979  -0.963  -0.908
169   A        -1.012  -1.041  -0.995  -0.941  -0.987  -0.916  -0.859  -0.879  -0.810
170   I        -0.694  -0.685  -0.655  -0.815  -0.807  -0.764  -0.717  -0.708  -0.654
171   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
172   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
173   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
174   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
175   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
176   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
177   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
178   Q        -1.114  -1.109  -1.039  -1.099  -1.098  -0.986  -0.939  -0.933  -0.844
179   Y         0.241   0.217   0.261   0.367   0.327   0.396  -0.087  -0.122  -0.069
180   T        -0.312  -0.291  -0.265  -0.373  -0.363  -0.290  -0.513  -0.489  -0.447
181   I         0.338   0.316   0.310   0.221   0.184   0.161   0.065   0.029   0.006
182   P         1.343   1.313   1.234   1.541   1.506   1.402   1.417   1.363   1.189
183   F         1.998   2.010   2.115   2.232   2.248   2.420   2.256   2.274   2.458
184   A         1.343   1.345   1.230   1.525   1.523   1.408   1.417   1.419   1.182
185   F        -1.012  -0.971  -0.976  -0.871  -0.824  -0.801  -0.859  -0.824  -0.795
186   I         1.343   1.349   1.234   1.399   1.400   1.255   1.417   1.425   1.190
187   S        -1.614  -1.610  -1.545  -1.396  -1.412  -1.290  -1.098  -1.093  -1.009
188   E        -0.109  -0.164  -0.175  -0.159  -0.245  -0.283  -0.260  -0.327  -0.336
189   V         1.998   2.010   2.115   1.994   2.001   2.176   2.256   2.274   2.458
190   V        -0.410  -0.460  -0.525  -0.292  -0.376  -0.472  -0.380  -0.438  -0.504
191   P        -0.597  -0.599  -0.610  -0.662  -0.678  -0.718  -0.619  -0.624  -0.609
192   G        -0.109  -0.082  -0.157  -0.135  -0.090  -0.239  -0.260  -0.227  -0.313
193   S         1.021   1.088   1.059   0.952   1.060   0.995   0.818   0.945   0.834
194   P         1.998   2.010   2.115   2.130   2.150   2.316   2.256   2.274   2.458
195   S         0.434   0.425   0.365   0.423   0.395   0.292   0.219   0.198   0.096
196   D        -0.898  -0.901  -0.928  -0.675  -0.678  -0.702  -0.739  -0.741  -0.745
197   K        -1.614  -1.610  -1.545  -1.519  -1.524  -1.415  -1.098  -1.093  -1.009
198   A         0.434   0.460   0.394   0.423   0.473   0.352   0.219   0.273   0.149
199   D         1.343   1.349   1.234   1.489   1.493   1.339   1.417   1.425   1.190
200   I         1.021   1.031   1.023   0.696   0.718   0.671   0.818   0.832   0.757
201   K         0.133   0.105  -0.041   0.419   0.379   0.186   0.100   0.060  -0.141
202   V        -0.711  -0.723  -0.671  -0.798  -0.811  -0.728  -0.739  -0.746  -0.672
203   D         0.434   0.391   0.362   0.430   0.354   0.292   0.219   0.151   0.090
204   D         1.998   2.010   2.115   1.973   1.987   2.155   2.256   2.274   2.458
205   K        -0.296  -0.281  -0.247  -0.558  -0.536  -0.479  -0.499  -0.478  -0.427
206   L         0.849   0.855   0.921   0.494   0.511   0.561   0.459   0.466   0.534
207   I        -0.006  -0.066  -0.125   0.130   0.037  -0.045  -0.091  -0.174  -0.256
208   S        -1.038  -1.023  -0.994  -1.010  -0.984  -0.944  -0.873  -0.860  -0.807
209   I        -0.220  -0.218  -0.218  -0.157  -0.168  -0.167  -0.404  -0.402  -0.391
210   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
211   G         0.959   1.030   1.018   0.868   0.995   0.938   0.691   0.830   0.748
212   N        -0.350  -0.350  -0.287  -0.462  -0.448  -0.343  -0.560  -0.557  -0.474
213   V         0.849   0.887   0.939   0.598   0.664   0.725   0.459   0.534   0.575
214   H         0.133   0.103  -0.047   0.477   0.430   0.184   0.100   0.059  -0.149
215   A         0.720   0.708   0.519   0.893   0.871   0.596   0.699   0.680   0.364
216   A        -0.597  -0.633  -0.615  -0.608  -0.676  -0.654  -0.619  -0.655  -0.615
217   N         1.343   1.317   1.231   1.446   1.405   1.301   1.417   1.370   1.184
218   H         0.133   0.148  -0.029   0.497   0.515   0.244   0.100   0.118  -0.126
219   S        -0.410  -0.449  -0.533  -0.287  -0.353  -0.497  -0.380  -0.424  -0.513
220   K        -0.597  -0.600  -0.604  -0.589  -0.589  -0.596  -0.619  -0.617  -0.604
221   L         1.343   1.317   1.231   1.186   1.161   1.046   1.417   1.370   1.184
222   Q        -1.012  -0.974  -0.973  -0.894  -0.843  -0.829  -0.859  -0.827  -0.793
223   N        -0.597  -0.581  -0.601  -0.577  -0.561  -0.582  -0.619  -0.604  -0.601
224   I         0.306   0.303   0.314  -0.028  -0.020  -0.023  -0.020  -0.022  -0.003
225   Q        -0.898  -0.871  -0.920  -0.677  -0.626  -0.724  -0.739  -0.711  -0.738
226   M        -1.313  -1.312  -1.273  -1.309  -1.297  -1.225  -0.979  -0.976  -0.912
227   V        -1.313  -1.296  -1.269  -1.220  -1.197  -1.127  -0.979  -0.963  -0.908
228   V         1.021   1.029   1.015   0.917   0.921   0.874   0.818   0.828   0.740
229   M        -1.012  -1.021  -0.988  -0.858  -0.868  -0.811  -0.859  -0.863  -0.804
230   K        -1.038  -1.054  -0.997  -1.026  -1.049  -0.966  -0.873  -0.887  -0.809
231   N        -0.564  -0.513  -0.592  -0.427  -0.353  -0.466  -0.560  -0.501  -0.581
232   E        -0.109  -0.080  -0.156  -0.120  -0.072  -0.193  -0.260  -0.220  -0.313
233   D         0.118   0.114   0.196  -0.148  -0.161  -0.035  -0.260  -0.266  -0.162
234   R        -1.012  -1.026  -0.982  -0.925  -0.944  -0.876  -0.859  -0.868  -0.800
235   P        -1.012  -0.998  -0.978  -0.958  -0.929  -0.909  -0.859  -0.846  -0.796
236   L         0.118   0.118   0.194  -0.336  -0.329  -0.233  -0.260  -0.262  -0.165
237   P        -1.012  -1.012  -0.979  -1.065  -1.077  -1.026  -0.859  -0.856  -0.797
238   V         0.720   0.697   0.542   0.767   0.724   0.481   0.699   0.661   0.402
239   L        -0.711  -0.685  -0.663  -0.961  -0.924  -0.888  -0.739  -0.716  -0.665
240   L         0.192   0.182   0.229  -0.245  -0.258  -0.203  -0.140  -0.158  -0.109
241   L        -0.296  -0.298  -0.259  -0.538  -0.543  -0.503  -0.499  -0.500  -0.443
242   R         1.998   2.010   2.115   2.064   2.078   2.248   2.256   2.274   2.458
243   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
244   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
245   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
246   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
247   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
248   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
249   E        -0.898  -0.896  -0.927  -0.765  -0.763  -0.819  -0.739  -0.735  -0.744
250   G        -0.711  -0.719  -0.666  -0.710  -0.723  -0.633  -0.739  -0.744  -0.667
251   Q        -0.597  -0.591  -0.606  -0.533  -0.525  -0.555  -0.619  -0.611  -0.605
252   I        -0.711  -0.722  -0.671  -0.936  -0.941  -0.874  -0.739  -0.745  -0.671
253   L        -0.597  -0.543  -0.598  -0.774  -0.705  -0.746  -0.619  -0.567  -0.598
254   K        -0.410  -0.420  -0.534  -0.218  -0.237  -0.421  -0.380  -0.390  -0.515
255   T         0.133   0.108  -0.049   0.005  -0.025  -0.273   0.100   0.065  -0.152
256   S        -0.597  -0.582  -0.599  -0.521  -0.495  -0.519  -0.619  -0.600  -0.597
257   L         1.998   2.010   2.115   1.768   1.789   1.945   2.256   2.274   2.458
258   T        -0.898  -0.878  -0.925  -0.829  -0.810  -0.905  -0.739  -0.718  -0.742
259   P         1.998   2.010   2.115   2.130   2.150   2.316   2.256   2.274   2.458
260   S        -0.597  -0.602  -0.606  -0.536  -0.547  -0.530  -0.619  -0.627  -0.606
261   R         0.829   0.860   0.931   0.552   0.614   0.702   0.416   0.476   0.557
262   N        -0.183  -0.207  -0.189  -0.253  -0.291  -0.259  -0.380  -0.403  -0.365
263   W         1.998   2.010   2.115   2.335   2.350   2.525   2.256   2.274   2.458
264   N        -1.012  -1.023  -0.988  -0.931  -0.934  -0.879  -0.859  -0.864  -0.804
265   G         1.998   2.010   2.115   2.093   2.105   2.277   2.256   2.274   2.458
266   R        -0.597  -0.627  -0.601  -0.499  -0.540  -0.496  -0.619  -0.644  -0.600
267   G         1.343   1.340   1.232   1.504   1.496   1.361   1.417   1.409   1.185
268   L         1.343   1.340   1.232   1.182   1.184   1.040   1.417   1.409   1.185
269   L         0.720   0.683   0.523   0.590   0.547   0.308   0.699   0.640   0.371
270   G         1.343   1.340   1.232   1.511   1.505   1.374   1.417   1.409   1.185
271   C         0.720   0.683   0.523   1.153   1.101   0.871   0.699   0.640   0.371
272   R         0.133   0.092  -0.055   0.366   0.307   0.105   0.100   0.044  -0.161
273   I         0.434   0.410   0.366   0.137   0.106   0.022   0.219   0.177   0.097
274   Q        -0.711  -0.696  -0.667  -0.773  -0.734  -0.715  -0.739  -0.725  -0.668
275   E        -0.694  -0.731  -0.672  -0.752  -0.824  -0.741  -0.717  -0.748  -0.670
276   L         0.254   0.246   0.284  -0.105  -0.113  -0.048  -0.091  -0.100  -0.046
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P40555
Output conservation file - output/P40555
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
