1     M         1.961   2.023   2.148   2.227   2.321   2.525   2.215   2.318   2.554
2     S         0.495   0.311   0.193   0.565   0.302   0.129   0.522   0.241   0.046
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     A        -1.148  -1.130  -1.073  -1.206  -1.167  -1.133  -1.026  -1.003  -0.912
7     F         1.063   1.130   0.971   1.312   1.411   1.191   1.058   1.162   0.829
8     A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     S        -1.361  -1.396  -1.382  -1.168  -1.220  -1.190  -1.040  -1.067  -1.010
10    S        -0.540  -0.629  -0.556  -0.516  -0.574  -0.444  -0.650  -0.726  -0.619
11    L         0.167   0.084   0.110   0.283   0.197   0.183   0.001  -0.104  -0.091
12    S        -1.016  -0.948  -0.998  -0.928  -0.823  -0.884  -0.910  -0.827  -0.843
13    K        -0.801  -0.794  -0.899  -0.612  -0.589  -0.759  -0.650  -0.649  -0.733
14    K        -1.146  -1.160  -1.034  -1.143  -1.137  -0.988  -1.040  -1.033  -0.877
15    L         0.495   0.382   0.215   0.492   0.352   0.135   0.522   0.340   0.080
16    Q         0.620   0.692   0.788   0.325   0.436   0.564   0.215   0.327   0.448
17    E        -0.141  -0.075  -0.015  -0.564  -0.474  -0.382  -0.452  -0.367  -0.284
18    I        -0.141  -0.093  -0.009  -0.317  -0.259  -0.117  -0.452  -0.389  -0.277
19    S         0.620   0.692   0.788   0.392   0.493   0.644   0.215   0.327   0.448
20    T        -0.141  -0.083  -0.030  -0.265  -0.178  -0.119  -0.452  -0.376  -0.303
21    S        -0.141  -0.083  -0.030  -0.508  -0.431  -0.339  -0.452  -0.376  -0.303
22    V         0.068   0.167   0.013   0.188   0.332   0.093  -0.118   0.027  -0.236
23    S         1.961   2.023   2.148   1.818   1.903   2.108   2.215   2.318   2.554
24    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    -        -0.514  -0.431  -0.469  -0.432  -0.296  -0.380  -0.563  -0.457  -0.502
37    -        -0.688  -0.666  -0.583  -0.856  -0.855  -0.733  -0.794  -0.767  -0.648
38    -        -0.583  -0.616  -0.544  -0.585  -0.626  -0.482  -0.676  -0.696  -0.598
39    -        -1.127  -1.147  -1.039  -1.102  -1.114  -0.963  -1.016  -1.020  -0.880
40    -        -0.978  -0.940  -0.987  -0.821  -0.787  -0.864  -0.846  -0.810  -0.827
41    -        -1.127  -1.135  -1.054  -1.237  -1.237  -1.116  -1.016  -1.010  -0.895
42    L        -0.671  -0.541  -0.539  -0.650  -0.441  -0.436  -0.780  -0.626  -0.599
43    P        -1.361  -1.360  -1.396  -1.109  -1.140  -1.284  -1.040  -1.036  -1.022
44    S        -0.178  -0.030  -0.375   0.151   0.366  -0.197  -0.129   0.071  -0.380
45    L        -0.178  -0.330  -0.468  -0.039  -0.222  -0.345  -0.129  -0.332  -0.500
46    A         1.961   2.023   2.148   1.782   1.855   2.071   2.215   2.318   2.554
47    Q        -0.456  -0.484  -0.527  -0.436  -0.516  -0.591  -0.519  -0.568  -0.587
48    S         0.020  -0.060   0.040  -0.048  -0.154  -0.015  -0.259  -0.341  -0.208
49    T         1.961   2.023   2.148   1.967   2.053   2.260   2.215   2.318   2.554
50    Q        -0.456  -0.529  -0.509  -0.416  -0.502  -0.489  -0.519  -0.587  -0.554
51    R         0.495   0.311   0.193   0.878   0.645   0.481   0.522   0.241   0.046
52    M        -0.178  -0.276  -0.415   0.327   0.204  -0.032  -0.129  -0.269  -0.432
53    V         0.167   0.094   0.074   0.139  -0.023  -0.085   0.001  -0.125  -0.161
54    Q         0.495   0.311   0.193   0.709   0.469   0.282   0.522   0.241   0.046
55    E         1.210   1.052   1.026   1.138   0.925   0.892   1.304   1.026   0.937
56    R         0.167   0.230   0.146   0.167   0.267   0.148   0.001   0.107  -0.043
57    L         0.167   0.120   0.123   0.101   0.056   0.078   0.001  -0.046  -0.066
58    G         1.961   2.023   2.148   2.153   2.237   2.449   2.215   2.318   2.554
59    Q        -0.456  -0.467  -0.508  -0.414  -0.435  -0.529  -0.519  -0.527  -0.563
60    V        -0.178  -0.276  -0.415   0.108  -0.044  -0.241  -0.129  -0.269  -0.432
61    T        -1.016  -1.000  -1.022  -1.031  -1.027  -1.059  -0.910  -0.894  -0.867
62    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
63    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
64    D         1.210   1.052   1.026   1.375   1.171   1.095   1.304   1.026   0.937
65    I        -0.178  -0.330  -0.468   0.128  -0.123  -0.373  -0.129  -0.332  -0.500
66    S         0.167   0.030   0.060   0.034  -0.188  -0.180   0.001  -0.190  -0.171
67    Q         0.495   0.362   0.205   0.650   0.452   0.178   0.522   0.312   0.065
68    L         1.961   2.023   2.148   1.748   1.835   2.038   2.215   2.318   2.554
69    P         1.961   2.023   2.148   2.138   2.226   2.434   2.215   2.318   2.554
70    R        -1.491  -1.505  -1.407  -1.450  -1.508  -1.320  -1.170  -1.164  -1.032
71    E         1.210   1.052   1.026   1.150   0.951   0.921   1.304   1.026   0.937
72    Y         1.961   2.023   2.148   2.162   2.252   2.458   2.215   2.318   2.554
73    T        -0.671  -0.591  -0.549  -0.747  -0.617  -0.567  -0.780  -0.681  -0.613
74    E         1.210   1.301   1.073   1.141   1.257   0.975   1.304   1.448   1.029
75    L         1.961   2.023   2.148   1.748   1.835   2.038   2.215   2.318   2.554
76    E         0.841   0.991   0.970   0.553   0.781   0.729   0.653   0.913   0.826
77    D        -1.837  -1.819  -1.718  -1.615  -1.585  -1.458  -1.301  -1.272  -1.140
78    K         0.020  -0.075   0.038  -0.060  -0.173   0.005  -0.259  -0.366  -0.217
79    V         0.841   0.991   0.970   0.938   1.146   1.139   0.653   0.913   0.826
80    D         0.167   0.328   0.182   0.231   0.505   0.241   0.001   0.249   0.026
81    T        -0.671  -0.708  -0.592  -0.854  -0.928  -0.773  -0.780  -0.801  -0.657
82    I         0.841   0.779   0.811   0.842   0.701   0.675   0.653   0.506   0.498
83    K         0.841   0.991   0.970   0.650   0.889   0.827   0.653   0.913   0.826
84    L        -1.491  -1.470  -1.398  -1.565  -1.584  -1.449  -1.170  -1.141  -1.026
85    I        -0.671  -0.690  -0.558  -0.795  -0.826  -0.626  -0.780  -0.778  -0.618
86    Y         0.841   0.873   0.870   1.062   1.108   1.100   0.653   0.691   0.622
87    N        -0.801  -0.742  -0.611  -1.050  -0.935  -0.762  -0.910  -0.839  -0.678
88    H        -0.671  -0.723  -0.592  -0.678  -0.784  -0.594  -0.780  -0.819  -0.658
89    F        -0.540  -0.515  -0.543  -0.399  -0.353  -0.388  -0.650  -0.609  -0.605
90    L         1.961   2.023   2.148   1.748   1.835   2.038   2.215   2.318   2.554
91    G        -1.016  -1.040  -1.016  -0.987  -1.018  -0.940  -0.910  -0.929  -0.861
92    V         0.841   0.807   0.819   0.870   0.805   0.803   0.653   0.561   0.515
93    T         1.210   1.052   1.026   1.323   1.116   1.083   1.304   1.026   0.937
94    A        -1.146  -1.150  -1.053  -1.399  -1.439  -1.293  -1.040  -1.026  -0.895
95    I        -1.016  -1.062  -1.014  -0.824  -0.887  -0.814  -0.910  -0.944  -0.858
96    Y         1.210   1.052   1.026   1.516   1.313   1.274   1.304   1.026   0.937
97    E         1.210   1.220   1.064   1.122   1.136   0.921   1.304   1.315   1.012
98    N         0.495   0.311   0.193   0.741   0.508   0.358   0.522   0.241   0.046
99    G         0.495   0.375   0.218   0.542   0.382   0.198   0.522   0.330   0.086
100   S         0.167   0.088   0.053   0.183   0.073   0.063   0.001  -0.138  -0.191
101   Y         1.961   2.023   2.148   2.162   2.252   2.458   2.215   2.318   2.554
102   D         1.961   2.023   2.148   2.051   2.158   2.345   2.215   2.318   2.554
103   Y         1.961   2.023   2.148   2.162   2.252   2.458   2.215   2.318   2.554
104   P         1.961   2.023   2.148   2.138   2.226   2.434   2.215   2.318   2.554
105   K        -0.671  -0.598  -0.577  -0.717  -0.602  -0.580  -0.780  -0.692  -0.641
106   Y         0.841   0.945   0.932   0.865   1.027   1.000   0.653   0.827   0.750
107   I        -0.671  -0.720  -0.575  -0.703  -0.733  -0.555  -0.780  -0.816  -0.643
108   N        -1.146  -1.059  -1.019  -1.094  -0.944  -0.905  -1.040  -0.948  -0.865
109   E         1.210   1.052   1.026   1.150   0.951   0.921   1.304   1.026   0.937
110   S         1.210   1.220   1.064   1.208   1.234   1.024   1.304   1.315   1.012
111   V        -0.540  -0.600  -0.552  -0.430  -0.491  -0.443  -0.650  -0.699  -0.614
112   N        -1.016  -0.957  -1.001  -0.916  -0.812  -0.893  -0.910  -0.834  -0.844
113   E         0.643   0.641   0.759   0.323   0.321   0.502   0.262   0.222   0.387
114   F         0.841   0.873   0.870   0.883   0.929   0.853   0.653   0.691   0.622
115   S         0.580   0.634   0.763   0.369   0.461   0.659   0.132   0.208   0.395
116   R         0.841   0.881   0.847   0.760   0.816   0.755   0.653   0.706   0.574
117   S        -0.540  -0.444  -0.513  -0.630  -0.476  -0.608  -0.650  -0.529  -0.572
118   V        -0.456  -0.268  -0.444  -0.207   0.044  -0.152  -0.519  -0.281  -0.484
119   A        -0.801  -0.735  -0.621  -0.980  -0.909  -0.711  -0.910  -0.831  -0.689
120   S        -1.491  -1.353  -1.380  -1.438  -1.215  -1.271  -1.170  -1.044  -1.012
121   K         0.841   0.991   0.970   0.760   0.979   0.953   0.653   0.913   0.826
122   L         0.841   0.928   0.900   0.761   0.895   0.798   0.653   0.797   0.684
123   T        -1.016  -1.016  -0.984  -0.842  -0.810  -0.733  -0.910  -0.895  -0.825
124   E        -1.016  -0.957  -1.001  -0.994  -0.887  -0.961  -0.910  -0.834  -0.844
125   L         1.210   1.346   1.091   1.104   1.277   0.969   1.304   1.519   1.065
126   T        -0.178  -0.219  -0.386  -0.061  -0.108  -0.368  -0.129  -0.197  -0.394
127   H        -0.801  -0.907  -0.963  -0.590  -0.752  -0.818  -0.650  -0.768  -0.801
128   A         0.167   0.065   0.085  -0.023  -0.202  -0.180   0.001  -0.134  -0.137
129   T         1.210   1.278   1.073   1.301   1.395   1.115   1.304   1.411   1.029
130   S        -0.456  -0.474  -0.490  -0.454  -0.443  -0.467  -0.519  -0.526  -0.530
131   A        -1.016  -1.014  -0.989  -1.046  -1.106  -0.979  -0.910  -0.903  -0.837
132   S        -0.456  -0.413  -0.512  -0.683  -0.681  -0.807  -0.519  -0.490  -0.571
133   E         0.841   0.789   0.809   0.622   0.519   0.532   0.653   0.524   0.494
134   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
135   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
136   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
137   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
138   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
139   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
140   A         1.210   1.052   1.026   1.158   0.955   0.949   1.304   1.026   0.937
141   Q         1.210   1.052   1.026   1.327   1.116   1.065   1.304   1.026   0.937
142   N         0.020   0.094   0.063  -0.222  -0.093  -0.153  -0.259  -0.152  -0.178
143   I        -0.671  -0.711  -0.583  -0.847  -0.937  -0.727  -0.780  -0.804  -0.649
144   L         1.210   1.052   1.026   1.071   0.847   0.792   1.304   1.026   0.937
145   V        -1.146  -1.150  -1.053  -1.141  -1.184  -1.063  -1.040  -1.026  -0.895
146   A        -1.016  -1.024  -0.994  -1.130  -1.157  -1.113  -0.910  -0.903  -0.835
147   P         0.495   0.382   0.215   0.798   0.617   0.340   0.522   0.340   0.080
148   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
149   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
150   G         0.167   0.039   0.077   0.384   0.170   0.210   0.001  -0.175  -0.151
151   P        -1.146  -1.150  -1.053  -1.245  -1.281  -1.117  -1.040  -1.026  -0.895
152   I        -1.491  -1.382  -1.390  -1.241  -1.143  -1.106  -1.170  -1.059  -1.018
153   K         1.961   2.023   2.148   1.884   1.974   2.176   2.215   2.318   2.554
154   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
155   E        -1.016  -0.977  -1.002  -0.995  -0.919  -0.934  -0.910  -0.870  -0.849
156   P         1.210   1.052   1.026   1.472   1.256   1.203   1.304   1.026   0.937
157   K         1.210   1.052   1.026   1.257   1.066   1.040   1.304   1.026   0.937
158   T         1.961   2.023   2.148   1.967   2.053   2.260   2.215   2.318   2.554
159   L         0.495   0.513   0.235   0.531   0.566   0.240   0.522   0.549   0.113
160   N         0.643   0.672   0.777   0.551   0.596   0.748   0.262   0.287   0.426
161   Y         0.020  -0.060   0.040   0.245   0.145   0.291  -0.259  -0.341  -0.208
162   A         1.961   2.023   2.148   1.782   1.855   2.071   2.215   2.318   2.554
163   L         0.167   0.154   0.077   0.074   0.032  -0.003   0.001  -0.067  -0.155
164   S         0.495   0.513   0.235   0.567   0.595   0.202   0.522   0.549   0.113
165   K         0.643   0.729   0.821   0.531   0.675   0.799   0.262   0.405   0.520
166   V         0.643   0.729   0.821   0.294   0.411   0.558   0.262   0.405   0.520
167   A         0.167   0.258   0.173  -0.019   0.116  -0.015   0.001   0.154   0.012
168   L         0.167   0.120   0.123  -0.017  -0.075  -0.091   0.001  -0.046  -0.066
169   N        -1.146  -1.155  -1.030  -1.168  -1.223  -1.012  -1.040  -1.030  -0.875
170   S         0.167   0.148   0.083   0.042  -0.031  -0.113   0.001  -0.054  -0.145
171   S        -0.456  -0.490  -0.498  -0.428  -0.469  -0.475  -0.519  -0.543  -0.540
172   E        -1.016  -1.068  -1.030  -1.258  -1.320  -1.281  -0.910  -0.943  -0.871
173   C        -1.837  -1.827  -1.748  -1.476  -1.516  -1.336  -1.301  -1.277  -1.162
174   L        -0.801  -0.766  -0.930  -0.725  -0.652  -0.892  -0.650  -0.619  -0.767
175   N        -1.127  -1.038  -1.019  -0.930  -0.774  -0.765  -1.016  -0.916  -0.862
176   K        -1.521  -1.498  -1.404  -1.463  -1.484  -1.285  -1.186  -1.156  -1.029
177   M        -1.148  -1.094  -1.025  -1.133  -1.056  -0.972  -1.026  -0.961  -0.866
178   F        -1.148  -1.104  -1.063  -0.841  -0.738  -0.729  -1.026  -0.973  -0.903
179   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
180   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
181   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
182   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
183   E        -1.016  -0.998  -0.984  -0.888  -0.848  -0.848  -0.910  -0.892  -0.832
184   Q        -0.801  -0.819  -0.950  -0.558  -0.579  -0.866  -0.650  -0.675  -0.788
185   P         0.495   0.635   0.284   0.813   1.007   0.492   0.522   0.728   0.189
186   L         1.961   2.023   2.148   1.748   1.835   2.038   2.215   2.318   2.554
187   A        -0.195  -0.108   0.014  -0.541  -0.431  -0.247  -0.519  -0.407  -0.245
188   S        -1.016  -1.004  -0.992  -1.104  -1.101  -1.094  -0.910  -0.894  -0.840
189   A        -1.016  -0.866  -0.928  -0.940  -0.761  -0.818  -0.910  -0.733  -0.766
190   L         1.210   1.052   1.026   1.123   0.934   0.910   1.304   1.026   0.937
191   L        -1.491  -1.510  -1.429  -1.495  -1.486  -1.423  -1.170  -1.167  -1.050
192   Q        -0.671  -0.590  -0.553  -0.900  -0.765  -0.698  -0.780  -0.692  -0.617
193   F         0.495   0.375   0.218   0.914   0.757   0.553   0.522   0.330   0.086
194   S         0.841   0.873   0.870   0.622   0.660   0.604   0.653   0.691   0.622
195   D        -1.016  -1.068  -1.030  -0.924  -0.973  -0.958  -0.910  -0.943  -0.871
196   V        -1.146  -1.150  -1.053  -1.309  -1.363  -1.221  -1.040  -1.026  -0.895
197   Q        -0.671  -0.651  -0.579  -0.854  -0.826  -0.703  -0.780  -0.749  -0.644
198   A        -0.671  -0.542  -0.542  -0.919  -0.731  -0.746  -0.780  -0.615  -0.599
199   K         1.210   1.220   1.064   1.218   1.241   1.017   1.304   1.315   1.012
200   I         0.643   0.647   0.760   0.569   0.546   0.704   0.262   0.235   0.388
201   A         0.580   0.640   0.769   0.315   0.419   0.630   0.132   0.220   0.408
202   Q        -0.195  -0.155  -0.043  -0.454  -0.396  -0.253  -0.519  -0.468  -0.322
203   A         0.167   0.140   0.078  -0.046  -0.148  -0.210   0.001  -0.069  -0.154
204   R         1.210   1.052   1.026   1.476   1.266   1.231   1.304   1.026   0.937
205   I         0.495   0.375   0.218   0.510   0.361   0.175   0.522   0.330   0.086
206   Q        -1.016  -1.068  -1.030  -0.928  -1.056  -1.033  -0.910  -0.943  -0.871
207   Q         1.210   1.052   1.026   1.362   1.170   1.143   1.304   1.026   0.937
208   D         1.961   2.023   2.148   2.051   2.158   2.345   2.215   2.318   2.554
209   T        -0.456  -0.529  -0.509  -0.454  -0.575  -0.579  -0.519  -0.587  -0.554
210   L        -0.456  -0.527  -0.502  -0.569  -0.701  -0.613  -0.519  -0.601  -0.557
211   I         1.961   2.023   2.148   2.093   2.187   2.389   2.215   2.318   2.554
212   Q        -0.456  -0.490  -0.498  -0.482  -0.528  -0.589  -0.519  -0.543  -0.540
213   T        -0.540  -0.600  -0.552  -0.658  -0.741  -0.664  -0.650  -0.699  -0.614
214   K         0.495   0.311   0.193   0.621   0.377   0.216   0.522   0.241   0.046
215   F         1.961   2.023   2.148   2.135   2.231   2.431   2.215   2.318   2.554
216   N         0.495   0.311   0.193   0.709   0.493   0.290   0.522   0.241   0.046
217   K         0.167   0.030   0.060  -0.006  -0.243  -0.249   0.001  -0.190  -0.171
218   N        -1.491  -1.495  -1.408  -1.268  -1.284  -1.152  -1.170  -1.157  -1.033
219   L        -1.016  -1.082  -1.012  -0.873  -0.929  -0.778  -0.910  -0.959  -0.857
220   R        -1.361  -1.227  -1.349  -0.985  -0.770  -1.009  -1.040  -0.898  -0.982
221   E        -0.195  -0.177  -0.048  -0.609  -0.611  -0.409  -0.519  -0.497  -0.328
222   R        -0.801  -0.819  -0.950  -0.529  -0.571  -0.761  -0.650  -0.675  -0.788
223   L         1.961   2.023   2.148   1.748   1.835   2.038   2.215   2.318   2.554
224   S        -1.491  -1.467  -1.419  -1.324  -1.260  -1.271  -1.170  -1.135  -1.042
225   F        -1.491  -1.452  -1.397  -1.315  -1.227  -1.176  -1.170  -1.126  -1.026
226   E        -1.491  -1.505  -1.407  -1.553  -1.507  -1.386  -1.170  -1.164  -1.032
227   I         0.167   0.030   0.060   0.251   0.062   0.050   0.001  -0.190  -0.171
228   G        -1.491  -1.434  -1.390  -1.578  -1.508  -1.422  -1.170  -1.103  -1.018
229   K        -1.491  -1.467  -1.419  -1.255  -1.252  -1.167  -1.170  -1.135  -1.042
230   A         0.643   0.754   0.820   0.210   0.386   0.469   0.262   0.455   0.516
231   D        -1.016  -1.063  -1.002  -0.861  -0.889  -0.829  -0.910  -0.947  -0.849
232   K        -0.111  -0.085   0.003  -0.239  -0.194  -0.062  -0.389  -0.369  -0.258
233   C        -0.456  -0.480  -0.486  -0.418  -0.457  -0.396  -0.519  -0.532  -0.525
234   R         0.167   0.120   0.123   0.321   0.260   0.237   0.001  -0.046  -0.066
235   K         0.167   0.088   0.053   0.034  -0.134  -0.202   0.001  -0.138  -0.191
236   D        -0.671  -0.575  -0.558  -0.761  -0.575  -0.609  -0.780  -0.663  -0.618
237   V         1.961   2.023   2.148   2.010   2.095   2.304   2.215   2.318   2.554
238   H        -1.016  -0.938  -0.958  -0.910  -0.819  -0.779  -0.910  -0.835  -0.808
239   S        -1.146  -1.111  -1.023  -1.148  -1.058  -0.950  -1.040  -0.990  -0.869
240   M         0.167   0.220   0.122   0.082   0.141   0.027   0.001   0.066  -0.076
241   R         1.961   2.023   2.148   2.124   2.208   2.420   2.215   2.318   2.554
242   L         0.841   0.991   0.970   0.618   0.837   0.809   0.653   0.913   0.826
243   R        -1.016  -0.940  -0.961  -0.811  -0.681  -0.713  -0.910  -0.810  -0.801
244   Y         0.643   0.641   0.759   0.496   0.423   0.574   0.262   0.222   0.387
245   D         1.210   1.052   1.026   1.375   1.171   1.095   1.304   1.026   0.937
246   V        -0.671  -0.708  -0.592  -0.841  -0.849  -0.698  -0.780  -0.801  -0.657
247   A        -0.540  -0.400  -0.513  -0.692  -0.531  -0.645  -0.650  -0.501  -0.575
248   R         0.643   0.641   0.759   0.531   0.473   0.639   0.262   0.222   0.387
249   T        -1.146  -1.134  -1.039  -1.294  -1.335  -1.128  -1.040  -1.015  -0.883
250   N        -0.178  -0.330  -0.468   0.085  -0.110  -0.340  -0.129  -0.332  -0.500
251   L        -0.456  -0.457  -0.525  -0.585  -0.607  -0.665  -0.519  -0.544  -0.586
252   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
253   N        -1.016  -0.983  -0.983  -1.061  -1.036  -1.034  -0.910  -0.869  -0.830
254   N        -1.016  -1.068  -1.030  -0.755  -0.850  -0.805  -0.910  -0.943  -0.871
255   K        -0.540  -0.430  -0.482  -0.746  -0.617  -0.663  -0.650  -0.528  -0.542
256   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
257   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
258   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
259   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
260   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
261   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
262   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
263   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
264   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
265   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
266   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
267   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
268   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
269   K         0.167   0.258   0.173   0.072   0.225   0.066   0.001   0.154   0.012
270   P         1.210   1.220   1.064   1.525   1.552   1.381   1.304   1.315   1.012
271   E         0.495   0.699   0.274   0.480   0.743   0.164   0.522   0.820   0.173
272   K        -0.178  -0.330  -0.468  -0.073  -0.299  -0.549  -0.129  -0.332  -0.500
273   E        -0.456  -0.570  -0.532  -0.630  -0.830  -0.782  -0.519  -0.642  -0.590
274   A        -0.540  -0.600  -0.552  -0.565  -0.678  -0.549  -0.650  -0.699  -0.614
275   S        -1.837  -1.787  -1.719  -1.705  -1.595  -1.525  -1.301  -1.250  -1.141
276   L         0.167   0.030   0.060  -0.034  -0.200  -0.165   0.001  -0.190  -0.171
277   R         0.167   0.039   0.077   0.321   0.119   0.138   0.001  -0.175  -0.151
278   V        -0.178  -0.330  -0.468  -0.005  -0.262  -0.548  -0.129  -0.332  -0.500
279   Q        -1.016  -0.975  -0.991  -1.053  -1.045  -1.002  -0.910  -0.864  -0.834
280   M        -0.456  -0.484  -0.527  -0.156  -0.232  -0.317  -0.519  -0.568  -0.587
281   E         0.495   0.382   0.215   0.504   0.355   0.117   0.522   0.340   0.080
282   T        -1.016  -1.068  -1.030  -0.962  -1.049  -1.011  -0.910  -0.943  -0.871
283   L         0.167   0.287   0.147  -0.027   0.140  -0.024   0.001   0.180  -0.032
284   E         1.961   2.023   2.148   1.789   1.870   2.079   2.215   2.318   2.554
285   D         1.210   1.301   1.073   1.375   1.519   1.178   1.304   1.448   1.029
286   Q         0.841   0.945   0.932   0.622   0.771   0.745   0.653   0.827   0.750
287   F         1.210   1.052   1.026   1.455   1.236   1.167   1.304   1.026   0.937
288   A         0.167   0.030   0.060   0.022  -0.180  -0.134   0.001  -0.190  -0.171
289   Q        -1.491  -1.510  -1.429  -1.352  -1.344  -1.276  -1.170  -1.167  -1.050
290   V        -0.456  -0.363  -0.436  -0.553  -0.418  -0.500  -0.519  -0.383  -0.461
291   T         0.167   0.120   0.123   0.220   0.181   0.177   0.001  -0.046  -0.066
292   E         1.210   1.301   1.073   1.150   1.268   0.994   1.304   1.448   1.029
293   D         0.167   0.030   0.060   0.246   0.080   0.075   0.001  -0.190  -0.171
294   A         1.961   2.023   2.148   1.782   1.855   2.071   2.215   2.318   2.554
295   T        -0.671  -0.723  -0.592  -0.638  -0.725  -0.539  -0.780  -0.819  -0.658
296   V        -1.146  -1.103  -1.027  -1.015  -0.937  -0.821  -1.040  -0.982  -0.870
297   C        -1.016  -1.016  -0.984  -0.833  -0.873  -0.798  -0.910  -0.895  -0.825
298   L         0.167   0.094   0.107   0.383   0.319   0.254   0.001  -0.088  -0.103
299   Q        -0.456  -0.541  -0.534  -0.480  -0.647  -0.667  -0.519  -0.621  -0.591
300   E        -0.456  -0.502  -0.516  -0.480  -0.531  -0.594  -0.519  -0.565  -0.565
301   V         0.495   0.362   0.205   0.708   0.528   0.276   0.522   0.312   0.065
302   I         0.167   0.287   0.147   0.030   0.201   0.020   0.001   0.180  -0.032
303   S        -1.016  -1.040  -1.016  -1.107  -1.120  -1.123  -0.910  -0.929  -0.861
304   H        -1.491  -1.467  -1.419  -1.384  -1.357  -1.294  -1.170  -1.135  -1.042
305   A        -0.456  -0.508  -0.517  -0.492  -0.558  -0.560  -0.519  -0.587  -0.570
306   N        -1.146  -1.150  -1.053  -1.190  -1.149  -1.010  -1.040  -1.026  -0.895
307   F         0.020  -0.060   0.040   0.146   0.054   0.195  -0.259  -0.341  -0.208
308   S         0.167   0.071   0.102  -0.073  -0.200  -0.185   0.001  -0.123  -0.106
309   E        -1.016  -1.036  -1.011  -0.960  -0.974  -0.922  -0.910  -0.925  -0.856
310   D        -1.016  -1.000  -0.989  -1.081  -1.057  -1.054  -0.910  -0.880  -0.830
311   L         0.841   0.991   0.970   0.633   0.850   0.826   0.653   0.913   0.826
312   K        -1.491  -1.510  -1.429  -1.453  -1.447  -1.293  -1.170  -1.167  -1.050
313   E         1.210   1.052   1.026   1.122   0.901   0.856   1.304   1.026   0.937
314   L         1.210   1.052   1.026   1.116   0.924   0.896   1.304   1.026   0.937
315   A        -0.195  -0.122  -0.001  -0.364  -0.240  -0.066  -0.519  -0.422  -0.265
316   K        -0.456  -0.365  -0.484  -0.587  -0.465  -0.666  -0.519  -0.410  -0.535
317   A         1.210   1.052   1.026   1.132   0.917   0.890   1.304   1.026   0.937
318   Q         1.961   2.023   2.148   1.990   2.080   2.283   2.215   2.318   2.554
319   A         0.495   0.527   0.269   0.469   0.522   0.171   0.522   0.569   0.165
320   E         0.020  -0.071   0.046  -0.385  -0.526  -0.345  -0.259  -0.359  -0.205
321   Y         0.841   0.756   0.802   1.028   0.880   0.927   0.653   0.459   0.480
322   F         0.495   0.628   0.279   1.003   1.176   0.740   0.522   0.717   0.181
323   E         0.167   0.084   0.110   0.037  -0.066  -0.066   0.001  -0.104  -0.091
324   T        -1.361  -1.388  -1.384  -1.280  -1.292  -1.289  -1.040  -1.060  -1.012
325   S         0.643   0.729   0.821   0.210   0.338   0.473   0.262   0.405   0.520
326   A        -0.456  -0.374  -0.472  -0.455  -0.331  -0.399  -0.519  -0.396  -0.507
327   G        -0.178  -0.233  -0.420  -0.149  -0.272  -0.520  -0.129  -0.213  -0.439
328   L        -0.456  -0.550  -0.530  -0.583  -0.742  -0.682  -0.519  -0.627  -0.589
329   M         0.841   0.945   0.932   0.665   0.812   0.808   0.653   0.827   0.750
330   K        -1.016  -0.903  -0.983  -1.027  -0.906  -0.975  -0.910  -0.807  -0.831
331   E        -0.111  -0.073   0.009  -0.277  -0.231  -0.101  -0.389  -0.349  -0.249
332   F        -0.671  -0.683  -0.560  -0.645  -0.650  -0.470  -0.780  -0.771  -0.619
333   L        -1.016  -1.066  -1.005  -1.024  -1.127  -1.049  -0.910  -0.948  -0.851
334   S        -1.127  -1.044  -1.047  -1.006  -0.867  -0.875  -1.016  -0.927  -0.889
335   N        -0.978  -0.936  -0.966  -0.987  -0.920  -0.978  -0.846  -0.795  -0.805
336   -        -0.693  -0.587  -0.581  -0.469  -0.327  -0.296  -0.785  -0.656  -0.642
337   -         0.620   0.636   0.759   0.308   0.344   0.520   0.215   0.211   0.387
338   -        -0.141  -0.139  -0.004  -0.336  -0.337  -0.141  -0.452  -0.447  -0.270
339   S        -0.054   0.038   0.033  -0.375  -0.252  -0.220  -0.331  -0.212  -0.209
340   F        -0.688  -0.638  -0.603  -0.635  -0.559  -0.522  -0.794  -0.729  -0.668
341   A        -1.148  -1.160  -1.073  -1.132  -1.152  -1.086  -1.026  -1.026  -0.912
342   E         0.232   0.275   0.124   0.164   0.222  -0.006   0.132   0.190  -0.063
343   E        -0.514  -0.425  -0.514  -0.553  -0.425  -0.627  -0.563  -0.447  -0.559
344   P        -0.688  -0.582  -0.600  -0.728  -0.610  -0.603  -0.794  -0.675  -0.666
345   E        -0.688  -0.668  -0.580  -1.012  -1.008  -0.876  -0.794  -0.760  -0.642
346   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
347   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
348   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
349   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
350   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
351   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
352   A        -1.246  -1.187  -1.078  -1.483  -1.399  -1.249  -1.118  -1.052  -0.917
353   E        -0.693  -0.686  -0.580  -0.758  -0.739  -0.588  -0.785  -0.777  -0.640
354   E         0.068   0.125   0.028   0.173   0.253   0.032  -0.118  -0.038  -0.212
355   E         0.964   1.048   0.919   0.822   0.934   0.729   0.882   1.018   0.723
356   K         1.063   1.092   0.966   1.003   1.046   0.838   1.058   1.096   0.818
357   P        -0.688  -0.638  -0.603  -0.479  -0.403  -0.359  -0.794  -0.729  -0.668
358   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
359   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
360   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
361   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
362   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
363   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
364   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
365   M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
366   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
367   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
368   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
369   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
370   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
371   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
372   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
373   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
374   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
375   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
376   A        -0.978  -0.890  -0.991  -0.856  -0.733  -0.966  -0.846  -0.745  -0.831
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P40531
Output conservation file - output/P40531
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
