1     M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
2     K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    M         0.789   0.713   0.602   1.052   0.956   0.760   0.791   0.663   0.438
30    Q        -0.620  -0.548  -0.607  -0.787  -0.695  -0.728  -0.748  -0.665  -0.691
31    G        -1.002  -1.004  -0.995  -1.130  -1.142  -1.129  -0.953  -0.947  -0.900
32    T        -0.654  -0.727  -0.658  -0.723  -0.803  -0.705  -0.769  -0.833  -0.742
33    A        -0.774  -0.752  -0.675  -0.899  -0.850  -0.756  -0.903  -0.863  -0.761
34    D        -1.092  -1.115  -1.033  -0.949  -0.948  -0.854  -1.037  -1.040  -0.932
35    L         1.393   1.421   1.481   1.279   1.316   1.419   1.510   1.549   1.642
36    S        -0.829  -0.942  -0.968  -0.634  -0.804  -0.882  -0.748  -0.865  -0.870
37    T        -0.620  -0.710  -0.636  -0.698  -0.820  -0.698  -0.748  -0.819  -0.721
38    S         1.393   1.421   1.481   1.361   1.394   1.498   1.510   1.549   1.642
39    K         1.393   1.421   1.481   1.374   1.432   1.510   1.510   1.549   1.642
40    L         1.393   1.421   1.481   1.279   1.316   1.419   1.510   1.549   1.642
41    G         1.393   1.421   1.481   1.341   1.377   1.478   1.510   1.549   1.642
42    T         0.789   0.852   0.622   0.874   0.965   0.630   0.791   0.887   0.475
43    K         1.393   1.421   1.481   1.374   1.432   1.510   1.510   1.549   1.642
44    K        -0.050  -0.058  -0.140  -0.158  -0.179  -0.290  -0.235  -0.269  -0.371
45    Y         1.393   1.421   1.481   1.578   1.623   1.709   1.510   1.549   1.642
46    W         1.393   1.421   1.481   1.606   1.646   1.737   1.510   1.549   1.642
47    D         0.491   0.563   0.506   0.368   0.483   0.376   0.278   0.400   0.255
48    E        -1.107  -1.089  -1.016  -1.245  -1.183  -1.088  -1.056  -1.021  -0.919
49    L        -0.050  -0.157  -0.156  -0.123  -0.300  -0.332  -0.235  -0.380  -0.393
50    Y         1.393   1.421   1.481   1.578   1.623   1.709   1.510   1.549   1.642
51    A        -1.385  -1.400  -1.314  -1.353  -1.382  -1.263  -1.158  -1.152  -1.038
52    L        -0.274  -0.286  -0.220  -0.475  -0.483  -0.375  -0.543  -0.565  -0.478
53    E         1.393   1.421   1.481   1.285   1.330   1.424   1.510   1.549   1.642
54    L        -1.385  -1.341  -1.296  -1.313  -1.257  -1.175  -1.158  -1.108  -1.025
55    E        -1.385  -1.298  -1.303  -1.331  -1.217  -1.234  -1.158  -1.065  -1.030
56    N         1.393   1.421   1.481   1.458   1.512   1.593   1.510   1.549   1.642
57    F         0.214   0.129  -0.041   0.402   0.302   0.079   0.176   0.053  -0.211
58    R        -1.385  -1.344  -1.302  -1.259  -1.184  -1.104  -1.158  -1.107  -1.029
59    R        -0.829  -0.762  -0.923  -0.808  -0.723  -0.961  -0.748  -0.669  -0.824
60    N         0.789   0.687   0.602   0.918   0.795   0.645   0.791   0.618   0.438
61    P         0.434   0.482   0.469   0.474   0.553   0.481   0.169   0.249   0.182
62    Q        -0.552  -0.610  -0.623  -0.631  -0.724  -0.717  -0.645  -0.718  -0.706
63    D         1.393   1.421   1.481   1.328   1.370   1.466   1.510   1.549   1.642
64    T        -0.050  -0.131  -0.157  -0.119  -0.292  -0.340  -0.235  -0.371  -0.395
65    G         1.393   1.421   1.481   1.341   1.377   1.478   1.510   1.549   1.642
66    D         0.214   0.183  -0.037   0.200   0.162  -0.181   0.176   0.126  -0.206
67    C         0.491   0.401   0.436   0.628   0.445   0.469   0.278   0.093   0.115
68    W         1.393   1.421   1.481   1.606   1.646   1.737   1.510   1.549   1.642
69    F         1.393   1.421   1.481   1.409   1.453   1.545   1.510   1.549   1.642
70    S        -1.002  -0.947  -0.984  -1.068  -1.017  -1.030  -0.953  -0.892  -0.889
71    D         0.789   0.687   0.602   0.770   0.629   0.483   0.791   0.618   0.438
72    S         0.434   0.545   0.486   0.317   0.494   0.383   0.169   0.367   0.215
73    D         0.214   0.105  -0.042   0.222   0.059  -0.190   0.176   0.017  -0.213
74    A         1.393   1.421   1.481   1.488   1.531   1.622   1.510   1.549   1.642
75    E         1.393   1.421   1.481   1.285   1.330   1.424   1.510   1.549   1.642
76    Q        -0.829  -0.792  -0.938  -0.817  -0.761  -0.997  -0.748  -0.701  -0.840
77    K         0.789   0.687   0.602   0.859   0.747   0.620   0.791   0.618   0.438
78    M         0.491   0.401   0.436   0.617   0.446   0.460   0.278   0.093   0.115
79    I         0.332   0.393   0.422   0.142   0.247   0.270  -0.030   0.078   0.087
80    D        -0.274  -0.173  -0.190  -0.421  -0.231  -0.321  -0.543  -0.394  -0.435
81    F         0.789   0.687   0.602   0.897   0.777   0.660   0.791   0.618   0.438
82    L         0.789   0.852   0.622   0.740   0.821   0.510   0.791   0.887   0.475
83    V        -1.385  -1.368  -1.310  -1.387  -1.399  -1.292  -1.158  -1.130  -1.035
84    D         0.789   0.713   0.602   0.770   0.668   0.483   0.791   0.663   0.438
85    N        -1.385  -1.404  -1.313  -1.239  -1.225  -1.116  -1.158  -1.154  -1.038
86    I        -0.725  -0.648  -0.647  -0.907  -0.806  -0.777  -0.851  -0.764  -0.733
87    G        -1.002  -1.087  -1.009  -1.003  -1.113  -1.001  -0.953  -1.014  -0.911
88    A        -1.280  -1.245  -1.260  -1.171  -1.132  -1.127  -1.056  -1.013  -0.993
89    -        -0.743  -0.774  -0.684  -1.082  -1.158  -1.017  -0.855  -0.881  -0.769
90    -        -0.298  -0.269  -0.215  -0.547  -0.479  -0.399  -0.592  -0.544  -0.473
91    -        -0.743  -0.774  -0.684  -0.961  -1.017  -0.869  -0.855  -0.881  -0.769
92    -        -0.298  -0.288  -0.215  -0.469  -0.487  -0.371  -0.592  -0.568  -0.472
93    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
94    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
95    Y        -1.385  -1.356  -1.296  -1.172  -1.164  -1.055  -1.158  -1.118  -1.025
96    R        -1.107  -1.037  -1.011  -1.203  -1.139  -1.055  -1.056  -0.979  -0.915
97    I        -0.552  -0.607  -0.619  -0.608  -0.717  -0.755  -0.645  -0.708  -0.702
98    S        -1.002  -1.032  -0.994  -0.910  -0.946  -0.877  -0.953  -0.968  -0.897
99    E        -1.280  -1.320  -1.278  -1.298  -1.380  -1.311  -1.056  -1.083  -1.008
100   N        -1.002  -0.963  -0.976  -1.009  -0.929  -0.959  -0.953  -0.901  -0.882
101   A        -1.385  -1.336  -1.297  -1.172  -1.113  -1.070  -1.158  -1.105  -1.026
102   S        -1.107  -1.078  -1.014  -1.075  -1.016  -0.924  -1.056  -1.014  -0.917
103   V        -0.725  -0.707  -0.665  -0.684  -0.682  -0.626  -0.851  -0.829  -0.752
104   V        -1.107  -1.109  -1.015  -1.109  -1.096  -0.940  -1.056  -1.035  -0.918
105   D         1.393   1.421   1.481   1.328   1.370   1.466   1.510   1.549   1.642
106   L         1.393   1.421   1.481   1.279   1.316   1.419   1.510   1.549   1.642
107   G         1.393   1.421   1.481   1.341   1.377   1.478   1.510   1.549   1.642
108   T         0.789   0.713   0.602   0.911   0.829   0.675   0.791   0.663   0.438
109   G         1.393   1.421   1.481   1.341   1.377   1.478   1.510   1.549   1.642
110   N         1.393   1.421   1.481   1.458   1.512   1.593   1.510   1.549   1.642
111   G         1.393   1.421   1.481   1.341   1.377   1.478   1.510   1.549   1.642
112   H         0.214   0.129  -0.041   0.577   0.451   0.191   0.176   0.053  -0.211
113   M         0.789   0.857   0.617   0.768   0.852   0.561   0.791   0.893   0.466
114   L         1.393   1.421   1.481   1.279   1.316   1.419   1.510   1.549   1.642
115   F         1.393   1.421   1.481   1.409   1.453   1.545   1.510   1.549   1.642
116   E        -1.385  -1.357  -1.304  -1.217  -1.173  -1.118  -1.158  -1.120  -1.031
117   L         0.789   0.797   0.614   0.740   0.752   0.498   0.791   0.800   0.461
118   H        -1.002  -0.935  -0.969  -0.836  -0.760  -0.808  -0.953  -0.881  -0.877
119   Q         0.214   0.183  -0.037   0.216   0.169  -0.149   0.176   0.126  -0.206
120   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
121   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
122   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
123   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
124   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
125   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
126   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
127   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
128   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
129   T        -1.107  -1.098  -1.013  -1.373  -1.367  -1.222  -1.056  -1.029  -0.916
130   E        -0.829  -0.810  -0.941  -0.732  -0.702  -0.909  -0.748  -0.723  -0.842
131   F        -0.829  -0.906  -0.964  -0.660  -0.777  -0.881  -0.748  -0.828  -0.866
132   Q        -1.385  -1.384  -1.299  -1.227  -1.221  -1.081  -1.158  -1.140  -1.027
133   G        -0.050  -0.093  -0.121  -0.099  -0.138  -0.179  -0.235  -0.277  -0.336
134   K        -1.385  -1.365  -1.296  -1.259  -1.192  -1.112  -1.158  -1.123  -1.025
135   L        -0.552  -0.399  -0.570  -0.541  -0.336  -0.543  -0.645  -0.439  -0.638
136   V        -1.385  -1.312  -1.293  -1.242  -1.128  -1.101  -1.158  -1.087  -1.023
137   G         1.393   1.421   1.481   1.341   1.377   1.478   1.510   1.549   1.642
138   I        -0.169  -0.136  -0.160  -0.325  -0.266  -0.311  -0.440  -0.380  -0.403
139   D         1.393   1.421   1.481   1.328   1.370   1.466   1.510   1.549   1.642
140   Y         1.393   1.421   1.481   1.578   1.623   1.709   1.510   1.549   1.642
141   S         1.393   1.421   1.481   1.361   1.394   1.498   1.510   1.549   1.642
142   E        -0.050  -0.003  -0.109  -0.097  -0.023  -0.157  -0.235  -0.154  -0.318
143   E        -1.385  -1.357  -1.304  -1.289  -1.224  -1.159  -1.158  -1.120  -1.031
144   S         0.491   0.437   0.447   0.410   0.306   0.315   0.278   0.164   0.137
145   V         0.789   0.687   0.602   0.872   0.734   0.602   0.791   0.618   0.438
146   K        -0.169  -0.207  -0.155  -0.429  -0.454  -0.385  -0.440  -0.462  -0.398
147   L         0.332   0.318   0.395   0.069   0.007   0.123  -0.030  -0.074   0.031
148   A         0.789   0.797   0.614   0.941   0.956   0.680   0.791   0.800   0.461
149   S        -1.385  -1.368  -1.298  -1.279  -1.256  -1.139  -1.158  -1.130  -1.027
150   N        -1.107  -1.091  -1.015  -1.192  -1.119  -1.028  -1.056  -1.022  -0.918
151   I         0.491   0.477   0.450   0.436   0.410   0.327   0.278   0.241   0.143
152   A        -0.050   0.027  -0.127  -0.047   0.049  -0.208  -0.235  -0.139  -0.351
153   E        -0.725  -0.679  -0.664  -0.813  -0.736  -0.703  -0.851  -0.804  -0.751
154   A        -1.385  -1.343  -1.295  -1.100  -1.037  -0.958  -1.158  -1.110  -1.024
155   T        -0.552  -0.574  -0.623  -0.531  -0.563  -0.640  -0.645  -0.685  -0.706
156   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
157   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
158   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
159   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
160   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
161   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
162   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
163   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
164   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
165   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
166   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
167   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
168   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
169   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
170   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
171   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
172   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
173   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
174   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
175   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
176   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
177   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
178   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
179   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
180   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
181   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
182   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
183   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
184   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
185   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
186   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
187   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
188   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
189   G        -1.385  -1.382  -1.311  -1.342  -1.341  -1.259  -1.158  -1.139  -1.035
190   V        -1.940  -1.889  -1.785  -1.715  -1.667  -1.501  -1.364  -1.311  -1.187
191   D        -1.409  -1.332  -1.303  -1.469  -1.367  -1.320  -1.171  -1.092  -1.029
192   N        -1.385  -1.349  -1.296  -1.490  -1.437  -1.347  -1.158  -1.113  -1.025
193   F        -1.385  -1.330  -1.297  -1.256  -1.195  -1.122  -1.158  -1.098  -1.025
194   I        -0.620  -0.525  -0.604  -0.716  -0.587  -0.691  -0.748  -0.646  -0.689
195   S        -1.663  -1.637  -1.558  -1.499  -1.499  -1.357  -1.261  -1.226  -1.118
196   F         1.393   1.421   1.481   1.409   1.453   1.545   1.510   1.549   1.642
197   Q        -0.725  -0.733  -0.658  -0.842  -0.841  -0.729  -0.851  -0.841  -0.744
198   Q        -0.328  -0.330  -0.526  -0.036  -0.048  -0.334  -0.338  -0.342  -0.582
199   A        -0.552  -0.655  -0.621  -0.465  -0.617  -0.579  -0.645  -0.745  -0.700
200   D         1.393   1.421   1.481   1.328   1.370   1.466   1.510   1.549   1.642
201   I        -0.552  -0.583  -0.603  -0.608  -0.639  -0.694  -0.645  -0.664  -0.678
202   F        -0.169  -0.196  -0.157  -0.410  -0.429  -0.367  -0.440  -0.443  -0.396
203   S        -1.663  -1.613  -1.549  -1.563  -1.482  -1.419  -1.261  -1.207  -1.112
204   G        -1.107  -1.025  -1.010  -1.328  -1.208  -1.169  -1.056  -0.972  -0.915
205   D        -1.385  -1.285  -1.290  -1.395  -1.272  -1.247  -1.158  -1.065  -1.021
206   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
207   -        -0.298  -0.282  -0.207  -0.523  -0.491  -0.377  -0.592  -0.565  -0.464
208   -        -0.130  -0.158  -0.164  -0.097  -0.140  -0.157  -0.329  -0.369  -0.396
209   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
210   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
211   W         0.373   0.338   0.402   0.423   0.334   0.418   0.050  -0.032   0.047
212   K        -1.109  -1.086  -1.023  -1.023  -0.982  -0.907  -1.044  -1.012  -0.922
213   P         0.373   0.372   0.415   0.391   0.374   0.406   0.050   0.036   0.072
214   G        -0.457  -0.511  -0.604  -0.394  -0.472  -0.610  -0.501  -0.570  -0.677
215   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
219   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
222   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
223   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
224   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   K        -0.552  -0.672  -0.617  -0.571  -0.751  -0.686  -0.645  -0.768  -0.698
228   Y        -0.169  -0.131  -0.169  -0.148  -0.085  -0.098  -0.440  -0.399  -0.418
229   D         0.789   0.894   0.620   0.795   0.930   0.567   0.791   0.950   0.472
230   I        -0.342  -0.344  -0.243  -0.608  -0.642  -0.478  -0.645  -0.642  -0.511
231   V        -0.050  -0.093  -0.121  -0.120  -0.172  -0.247  -0.235  -0.277  -0.336
232   L         1.393   1.421   1.481   1.279   1.316   1.419   1.510   1.549   1.642
233   D         1.393   1.421   1.481   1.328   1.370   1.466   1.510   1.549   1.642
234   K         1.393   1.421   1.481   1.374   1.432   1.510   1.510   1.549   1.642
235   G         1.393   1.421   1.481   1.341   1.377   1.478   1.510   1.549   1.642
236   T         1.393   1.421   1.481   1.421   1.469   1.557   1.510   1.549   1.642
237   L         0.491   0.401   0.436   0.305   0.135   0.183   0.278   0.093   0.115
238   D         1.393   1.421   1.481   1.328   1.370   1.466   1.510   1.549   1.642
239   A         1.393   1.421   1.481   1.488   1.531   1.622   1.510   1.549   1.642
240   I         0.789   0.713   0.602   0.874   0.783   0.604   0.791   0.663   0.438
241   S         0.332   0.318   0.395   0.182   0.120   0.237  -0.030  -0.074   0.031
242   L         1.393   1.421   1.481   1.279   1.316   1.419   1.510   1.549   1.642
243   S         0.491   0.563   0.506   0.400   0.506   0.406   0.278   0.400   0.255
244   G        -0.274  -0.261  -0.209  -0.473  -0.477  -0.396  -0.543  -0.525  -0.463
245   M        -1.385  -1.330  -1.297  -1.450  -1.380  -1.323  -1.158  -1.098  -1.025
246   K        -0.829  -0.906  -0.964  -0.677  -0.804  -0.881  -0.748  -0.828  -0.866
247   I        -1.107  -1.109  -1.015  -1.207  -1.217  -1.061  -1.056  -1.035  -0.918
248   N        -1.107  -1.050  -1.009  -1.235  -1.146  -1.077  -1.056  -0.992  -0.914
249   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
250   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
251   G        -0.739  -0.737  -0.664  -0.840  -0.823  -0.722  -0.862  -0.851  -0.749
252   K        -0.552  -0.381  -0.568  -0.651  -0.389  -0.676  -0.645  -0.425  -0.641
253   L        -0.552  -0.503  -0.609  -0.562  -0.497  -0.669  -0.645  -0.615  -0.691
254   D        -1.002  -1.058  -1.005  -0.898  -0.944  -0.875  -0.953  -0.989  -0.907
255   V        -0.725  -0.746  -0.662  -0.918  -0.961  -0.830  -0.851  -0.853  -0.748
256   V        -0.552  -0.655  -0.621  -0.408  -0.534  -0.478  -0.645  -0.745  -0.700
257   D        -0.328  -0.500  -0.566  -0.280  -0.552  -0.663  -0.338  -0.551  -0.631
258   V         0.214   0.129  -0.041   0.348   0.233  -0.027   0.176   0.053  -0.211
259   Y         1.393   1.421   1.481   1.578   1.623   1.709   1.510   1.549   1.642
260   A        -1.002  -1.041  -0.995  -0.851  -0.934  -0.867  -0.953  -0.975  -0.900
261   G        -1.385  -1.415  -1.320  -1.348  -1.382  -1.232  -1.158  -1.161  -1.042
262   V        -0.725  -0.669  -0.658  -0.641  -0.582  -0.513  -0.851  -0.793  -0.744
263   V         0.789   0.904   0.625   0.872   1.015   0.641   0.791   0.965   0.481
264   E        -0.829  -0.942  -0.958  -0.784  -0.959  -0.976  -0.748  -0.864  -0.860
265   R        -1.107  -1.120  -1.015  -0.968  -0.990  -0.827  -1.056  -1.044  -0.918
266   I        -0.342  -0.284  -0.223  -0.505  -0.399  -0.325  -0.645  -0.566  -0.485
267   L        -0.169  -0.128  -0.153  -0.286  -0.233  -0.245  -0.440  -0.365  -0.392
268   K        -1.663  -1.619  -1.556  -1.519  -1.453  -1.367  -1.261  -1.214  -1.116
269   K        -1.002  -0.891  -0.970  -0.816  -0.632  -0.799  -0.953  -0.826  -0.874
270   D        -0.620  -0.583  -0.600  -0.680  -0.626  -0.628  -0.748  -0.699  -0.685
271   G         0.282   0.325   0.400  -0.052   0.010   0.137  -0.132  -0.058   0.042
272   I        -0.169  -0.200  -0.159  -0.298  -0.325  -0.270  -0.440  -0.458  -0.404
273   F        -0.169  -0.126  -0.151  -0.383  -0.289  -0.332  -0.440  -0.361  -0.390
274   L         1.393   1.421   1.481   1.279   1.316   1.419   1.510   1.549   1.642
275   I         0.789   0.713   0.602   0.874   0.783   0.604   0.791   0.663   0.438
276   T         1.393   1.421   1.481   1.421   1.469   1.557   1.510   1.549   1.642
277   S         1.393   1.421   1.481   1.361   1.394   1.498   1.510   1.549   1.642
278   C         1.393   1.421   1.481   1.613   1.656   1.744   1.510   1.549   1.642
279   N         1.393   1.421   1.481   1.458   1.512   1.593   1.510   1.549   1.642
280   F         0.491   0.401   0.436   0.495   0.349   0.399   0.278   0.093   0.115
281   T         1.393   1.421   1.481   1.421   1.469   1.557   1.510   1.549   1.642
282   Q        -1.002  -1.010  -0.974  -1.056  -1.065  -1.016  -0.953  -0.941  -0.879
283   D        -0.620  -0.640  -0.620  -0.827  -0.841  -0.793  -0.748  -0.756  -0.705
284   E         1.393   1.421   1.481   1.285   1.330   1.424   1.510   1.549   1.642
285   L         1.393   1.421   1.481   1.279   1.316   1.419   1.510   1.549   1.642
286   V        -0.552  -0.672  -0.625  -0.585  -0.775  -0.733  -0.645  -0.768  -0.707
287   K         0.214   0.032  -0.066   0.268   0.011  -0.192   0.176  -0.087  -0.250
288   I         0.214   0.032  -0.066   0.403   0.174   0.039   0.176  -0.087  -0.250
289   I        -0.050  -0.131  -0.157  -0.033  -0.176  -0.194  -0.235  -0.371  -0.395
290   E         0.282   0.310   0.393  -0.048   0.006   0.131  -0.132  -0.090   0.028
291   T        -0.050  -0.037  -0.140  -0.056  -0.051  -0.206  -0.235  -0.233  -0.370
292   D         0.214   0.201  -0.025   0.243   0.226  -0.122   0.176   0.145  -0.188
293   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
294   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
295   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
296   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
297   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
298   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
299   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
300   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
301   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
302   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
303   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
304   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
305   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
306   N        -1.107  -1.032  -1.013  -1.132  -1.032  -0.973  -1.056  -0.972  -0.917
307   L         0.789   0.687   0.602   0.739   0.601   0.476   0.791   0.618   0.438
308   K        -0.829  -0.906  -0.964  -0.721  -0.825  -0.952  -0.748  -0.828  -0.866
309   M        -1.002  -0.965  -0.987  -0.895  -0.840  -0.885  -0.953  -0.899  -0.892
310   W         0.214   0.032  -0.066   0.567   0.319   0.157   0.176  -0.087  -0.250
311   K        -1.280  -1.289  -1.282  -1.277  -1.305  -1.333  -1.056  -1.056  -1.011
312   T        -1.663  -1.584  -1.549  -1.396  -1.273  -1.235  -1.261  -1.185  -1.111
313   I         0.282   0.307   0.392   0.039   0.077   0.210  -0.132  -0.095   0.026
314   K        -1.002  -1.067  -0.997  -0.971  -1.049  -0.979  -0.953  -0.999  -0.902
315   Y         0.789   0.687   0.602   1.037   0.903   0.758   0.791   0.618   0.438
316   P         1.393   1.421   1.481   1.599   1.636   1.730   1.510   1.549   1.642
317   V        -0.169  -0.084  -0.157  -0.340  -0.245  -0.305  -0.440  -0.342  -0.402
318   F         1.393   1.421   1.481   1.409   1.453   1.545   1.510   1.549   1.642
319   Q        -0.620  -0.659  -0.626  -0.670  -0.732  -0.652  -0.748  -0.770  -0.711
320   F         1.393   1.421   1.481   1.409   1.453   1.545   1.510   1.549   1.642
321   G         0.789   0.687   0.602   0.816   0.683   0.568   0.791   0.618   0.438
322   G         1.393   1.421   1.481   1.341   1.377   1.478   1.510   1.549   1.642
323   V         0.214   0.105  -0.042   0.332   0.170  -0.061   0.176   0.017  -0.213
324   Q        -0.328  -0.390  -0.540  -0.214  -0.295  -0.544  -0.338  -0.416  -0.599
325   G         1.393   1.421   1.481   1.341   1.377   1.478   1.510   1.549   1.642
326   A        -0.552  -0.505  -0.585  -0.549  -0.467  -0.575  -0.645  -0.567  -0.656
327   T         0.789   0.687   0.602   0.874   0.740   0.595   0.791   0.618   0.438
328   I        -0.050  -0.122  -0.134  -0.067  -0.161  -0.212  -0.235  -0.322  -0.360
329   C        -0.050  -0.089  -0.152   0.101  -0.024  -0.113  -0.235  -0.322  -0.387
330   S        -0.169  -0.235  -0.170  -0.335  -0.427  -0.318  -0.440  -0.509  -0.419
331   V        -0.169  -0.177  -0.157  -0.324  -0.314  -0.303  -0.440  -0.419  -0.396
332   A         0.789   0.713   0.602   0.977   0.890   0.736   0.791   0.663   0.438
333   F         1.393   1.421   1.481   1.409   1.453   1.545   1.510   1.549   1.642
334   V        -1.002  -0.943  -0.982  -0.973  -0.883  -0.959  -0.953  -0.896  -0.888
335   K         0.214   0.155  -0.034   0.331   0.258  -0.012   0.176   0.084  -0.201
336   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
337   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
339   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
340   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
341   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
342   N        -1.002  -1.009  -0.990  -0.952  -0.971  -0.945  -0.953  -0.950  -0.895
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P40516
Output conservation file - output/P40516
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
