1     M         2.257   2.285   2.427   2.560   2.603   2.833   2.584   2.629   2.881
2     F        -0.445  -0.474  -0.365  -0.551  -0.586  -0.423  -0.611  -0.636  -0.498
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     L         0.277   0.330   0.312  -0.123  -0.064  -0.056  -0.043   0.011   0.012
5     R         2.257   2.285   2.427   2.416   2.455   2.686   2.584   2.629   2.881
6     S        -1.264  -1.219  -1.181  -1.316  -1.237  -1.181  -1.011  -0.966  -0.887
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     V        -0.427  -0.359  -0.335  -0.625  -0.523  -0.488  -0.596  -0.518  -0.466
10    N        -1.616  -1.607  -1.525  -1.488  -1.499  -1.368  -1.149  -1.135  -1.020
11    R         0.075   0.149  -0.103   0.339   0.448   0.034   0.095   0.196  -0.148
12    A        -1.131  -1.095  -1.135  -0.844  -0.807  -0.857  -0.873  -0.835  -0.838
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    V         0.144   0.179   0.232  -0.246  -0.192  -0.135  -0.181  -0.131  -0.082
23    T         0.277   0.346   0.328   0.153   0.237   0.240  -0.043   0.037   0.035
24    R        -0.779  -0.814  -0.797  -0.668  -0.739  -0.722  -0.734  -0.768  -0.716
25    S         0.494   0.533   0.456   0.469   0.527   0.413   0.372   0.429   0.280
26    I        -0.914  -0.899  -0.817  -0.770  -0.738  -0.610  -0.857  -0.836  -0.728
27    L        -0.445  -0.458  -0.368  -0.586  -0.588  -0.438  -0.611  -0.619  -0.502
28    T        -0.912  -0.850  -0.814  -0.763  -0.681  -0.602  -0.873  -0.814  -0.736
29    T         0.075   0.119  -0.096   0.065   0.120  -0.193   0.095   0.149  -0.139
30    P        -0.779  -0.726  -0.744  -0.662  -0.572  -0.605  -0.734  -0.673  -0.661
31    K         0.913   0.955   1.037   0.833   0.902   1.007   0.510   0.584   0.662
32    P        -1.295  -1.313  -1.234  -1.100  -1.139  -1.037  -1.028  -1.038  -0.928
33    A        -0.740  -0.719  -0.756  -0.703  -0.681  -0.742  -0.667  -0.640  -0.663
34    V         0.639   0.767   0.522   0.720   0.905   0.541   0.598   0.793   0.388
35    V        -0.740  -0.745  -0.755  -0.613  -0.622  -0.627  -0.667  -0.673  -0.663
36    K        -0.892  -0.816  -0.805  -0.920  -0.819  -0.786  -0.847  -0.768  -0.723
37    S        -1.384  -1.363  -1.256  -1.312  -1.269  -1.124  -1.103  -1.078  -0.946
38    S         0.494   0.440   0.403   0.409   0.329   0.228   0.372   0.283   0.194
39    W        -0.338  -0.272  -0.295  -0.120  -0.045  -0.021  -0.486  -0.412  -0.418
40    R        -0.779  -0.747  -0.760  -0.703  -0.684  -0.654  -0.734  -0.707  -0.680
41    V        -0.779  -0.769  -0.764  -0.897  -0.898  -0.884  -0.734  -0.727  -0.683
42    F        -0.560  -0.559  -0.668  -0.213  -0.227  -0.389  -0.458  -0.457  -0.566
43    T         0.075   0.079  -0.090   0.354   0.361   0.115   0.095   0.099  -0.130
44    V        -0.208  -0.290  -0.280  -0.238  -0.367  -0.380  -0.319  -0.422  -0.399
45    -        -0.087  -0.087  -0.164  -0.142  -0.138  -0.253  -0.125  -0.125  -0.231
46    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
47    -        -0.450  -0.456  -0.363  -0.527  -0.540  -0.420  -0.602  -0.609  -0.491
48    -        -1.013  -0.994  -0.881  -1.192  -1.158  -1.001  -0.956  -0.930  -0.793
49    -         2.257   2.285   2.427   2.443   2.483   2.714   2.584   2.629   2.881
50    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    -        -0.450  -0.407  -0.356  -0.449  -0.378  -0.319  -0.602  -0.545  -0.482
54    -         0.202   0.248   0.284  -0.129  -0.052  -0.015  -0.120  -0.050  -0.015
55    -         0.869   0.877   1.005   0.681   0.681   0.875   0.417   0.416   0.591
56    A         0.277   0.365   0.333  -0.014   0.120   0.094  -0.043   0.085   0.049
57    N        -0.892  -0.896  -0.823  -0.888  -0.877  -0.786  -0.847  -0.843  -0.739
58    S         0.963   0.941   1.031   0.677   0.635   0.756   0.618   0.553   0.650
59    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
60    K        -0.450  -0.443  -0.363  -0.635  -0.628  -0.500  -0.602  -0.593  -0.491
61    R         2.257   2.285   2.427   2.430   2.475   2.701   2.584   2.629   2.881
62    C        -0.914  -0.893  -0.823  -0.799  -0.788  -0.652  -0.857  -0.833  -0.735
63    F        -0.268  -0.301  -0.301  -0.329  -0.394  -0.459  -0.366  -0.411  -0.411
64    T         0.113   0.178   0.224   0.003   0.085   0.166  -0.248  -0.165  -0.104
65    P        -1.013  -0.973  -0.881  -0.770  -0.691  -0.570  -0.956  -0.912  -0.793
66    A         0.326   0.480   0.349   0.403   0.652   0.420   0.106   0.347   0.106
67    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
68    A        -0.450  -0.462  -0.394  -0.517  -0.529  -0.448  -0.602  -0.616  -0.529
69    I         0.326   0.334   0.312   0.366   0.364   0.315   0.106   0.111   0.047
70    M        -1.013  -0.991  -0.881  -0.760  -0.732  -0.560  -0.956  -0.928  -0.793
71    R        -1.264  -1.170  -1.179  -1.151  -1.050  -1.001  -1.011  -0.927  -0.885
72    N        -0.779  -0.846  -0.794  -0.693  -0.799  -0.716  -0.734  -0.795  -0.713
73    Q        -0.779  -0.856  -0.809  -0.685  -0.813  -0.781  -0.734  -0.804  -0.726
74    E        -0.912  -0.864  -0.822  -0.903  -0.819  -0.719  -0.873  -0.823  -0.741
75    T        -1.264  -1.272  -1.196  -1.268  -1.280  -1.192  -1.011  -1.008  -0.898
76    Q        -0.427  -0.366  -0.342  -0.550  -0.473  -0.405  -0.596  -0.529  -0.477
77    R        -0.912  -0.861  -0.816  -0.951  -0.912  -0.799  -0.873  -0.822  -0.737
78    V         0.913   0.993   1.085   0.486   0.628   0.747   0.510   0.664   0.768
79    G        -1.616  -1.592  -1.544  -1.358  -1.341  -1.261  -1.149  -1.123  -1.035
80    D        -0.912  -0.945  -0.819  -1.049  -1.104  -0.915  -0.873  -0.889  -0.739
81    I        -0.779  -0.850  -0.773  -0.660  -0.764  -0.650  -0.734  -0.796  -0.691
82    L         2.257   2.285   2.427   2.090   2.132   2.353   2.584   2.629   2.881
83    Q        -1.264  -1.250  -1.200  -1.182  -1.166  -1.069  -1.011  -0.990  -0.902
84    S        -0.208  -0.240  -0.274  -0.240  -0.285  -0.310  -0.319  -0.365  -0.394
85    E         2.257   2.285   2.427   2.021   2.063   2.282   2.584   2.629   2.881
86    L         0.277   0.315   0.305  -0.004   0.045   0.063  -0.043  -0.010   0.001
87    K        -1.264  -1.202  -1.179  -1.128  -1.033  -1.001  -1.011  -0.950  -0.885
88    I        -0.294  -0.220  -0.270  -0.353  -0.227  -0.285  -0.458  -0.374  -0.396
89    E         0.762   0.784   0.543   0.631   0.666   0.298   0.787   0.820   0.422
90    K        -1.264  -1.207  -1.173  -1.219  -1.117  -1.095  -1.011  -0.956  -0.881
91    E        -0.779  -0.769  -0.738  -1.035  -0.982  -0.952  -0.734  -0.708  -0.650
92    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
93    L         0.064   0.081   0.200  -0.245  -0.221  -0.051  -0.305  -0.286  -0.134
94    P        -0.740  -0.768  -0.753  -0.648  -0.728  -0.741  -0.667  -0.696  -0.661
95    E        -0.892  -0.867  -0.821  -1.102  -1.064  -1.022  -0.847  -0.817  -0.737
96    S         0.075   0.187  -0.070   0.003   0.162  -0.209   0.095   0.246  -0.103
97    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
98    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
99    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
100   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
101   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
102   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
103   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
104   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
105   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
106   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
107   T        -1.384  -1.353  -1.256  -1.282  -1.236  -1.093  -1.103  -1.071  -0.946
108   S        -0.445  -0.436  -0.346  -0.535  -0.527  -0.388  -0.611  -0.599  -0.479
109   L         1.491   1.498   1.376   1.401   1.416   1.253   1.616   1.624   1.367
110   D         0.848   0.875   1.006   0.664   0.707   0.910   0.372   0.411   0.593
111   -        -0.892  -0.891  -0.820  -0.934  -0.920  -0.795  -0.847  -0.839  -0.736
112   S        -0.560  -0.540  -0.422  -0.965  -0.935  -0.771  -0.734  -0.708  -0.563
113   F        -1.295  -1.324  -1.234  -1.047  -1.083  -0.951  -1.028  -1.047  -0.928
114   N        -1.295  -1.286  -1.204  -1.122  -1.112  -1.000  -1.028  -1.015  -0.902
115   D        -0.338  -0.352  -0.292  -0.528  -0.544  -0.471  -0.486  -0.497  -0.415
116   F         0.639   0.623   0.478   0.801   0.760   0.543   0.598   0.563   0.316
117   L         1.423   1.423   1.332   1.304   1.305   1.170   1.501   1.494   1.282
118   N        -0.892  -0.870  -0.805  -1.119  -1.083  -0.992  -0.847  -0.821  -0.723
119   K         0.639   0.623   0.475   0.861   0.843   0.612   0.598   0.570   0.311
120   Y        -0.338  -0.335  -0.279  -0.371  -0.363  -0.279  -0.486  -0.468  -0.391
121   K         0.075   0.090  -0.095   0.458   0.476   0.220   0.095   0.114  -0.138
122   F         1.114   1.097   1.119   1.168   1.142   1.159   0.925   0.878   0.840
123   S        -0.427  -0.411  -0.330  -0.794  -0.756  -0.641  -0.596  -0.564  -0.457
124   L        -0.208  -0.123  -0.204  -0.190  -0.061  -0.190  -0.319  -0.207  -0.302
125   V         0.762   0.718   0.554   0.871   0.810   0.553   0.787   0.717   0.440
126   E        -0.779  -0.747  -0.748  -0.885  -0.791  -0.816  -0.734  -0.688  -0.660
127   T        -1.131  -1.132  -1.115  -0.856  -0.881  -0.842  -0.873  -0.870  -0.820
128   P         0.428   0.417   0.387   0.484   0.483   0.384   0.234   0.227   0.148
129   G         1.491   1.417   1.360   1.729   1.629   1.544   1.616   1.484   1.336
130   K        -0.208  -0.196  -0.236  -0.114  -0.101  -0.160  -0.319  -0.303  -0.339
131   N        -0.779  -0.839  -0.798  -0.872  -0.976  -0.961  -0.734  -0.789  -0.716
132   E        -0.779  -0.778  -0.769  -1.035  -1.022  -1.030  -0.734  -0.728  -0.685
133   A        -0.294  -0.330  -0.287  -0.458  -0.508  -0.434  -0.458  -0.485  -0.411
134   E        -0.208  -0.187  -0.234  -0.350  -0.334  -0.343  -0.319  -0.303  -0.340
135   I         1.114   1.213   1.204   0.881   1.031   1.007   0.925   1.105   1.021
136   V         1.240   1.324   1.244   1.242   1.370   1.239   1.168   1.316   1.104
137   R         1.114   1.213   1.204   1.171   1.324   1.301   0.925   1.105   1.021
138   R        -0.779  -0.783  -0.768  -0.669  -0.694  -0.683  -0.734  -0.738  -0.688
139   T        -0.779  -0.820  -0.779  -0.690  -0.770  -0.693  -0.734  -0.770  -0.696
140   E        -1.131  -1.148  -1.140  -1.175  -1.176  -1.177  -0.873  -0.885  -0.844
141   S        -0.912  -0.866  -0.815  -0.903  -0.827  -0.750  -0.873  -0.827  -0.736
142   G         0.428   0.427   0.380   0.552   0.548   0.460   0.234   0.231   0.138
143   E         0.762   0.703   0.533   0.718   0.640   0.436   0.787   0.693   0.405
144   T        -0.560  -0.658  -0.719  -0.263  -0.413  -0.511  -0.458  -0.569  -0.622
145   V         0.428   0.434   0.413   0.483   0.514   0.466   0.234   0.266   0.201
146   H        -0.208  -0.132  -0.204   0.072   0.183   0.094  -0.319  -0.214  -0.302
147   V         0.913   0.913   1.019   0.695   0.683   0.838   0.510   0.493   0.623
148   F        -0.560  -0.546  -0.656  -0.333  -0.304  -0.505  -0.458  -0.439  -0.551
149   F         0.762   0.638   0.525   1.026   0.868   0.714   0.787   0.594   0.393
150   D         0.428   0.346   0.335   0.369   0.223   0.180   0.234   0.102   0.065
151   V         0.428   0.355   0.349   0.375   0.261   0.220   0.234   0.128   0.085
152   A        -0.560  -0.653  -0.713  -0.482  -0.629  -0.769  -0.458  -0.564  -0.616
153   Q        -0.208  -0.268  -0.275  -0.143  -0.243  -0.305  -0.319  -0.389  -0.394
154   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
155   I         0.762   0.836   0.575   0.882   0.983   0.607   0.787   0.897   0.473
156   A        -0.294  -0.249  -0.281  -0.363  -0.295  -0.327  -0.458  -0.407  -0.408
157   N         0.277   0.222   0.293   0.172   0.104   0.220  -0.043  -0.111  -0.013
158   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
159   L        -0.338  -0.410  -0.352  -0.621  -0.734  -0.663  -0.486  -0.565  -0.484
160   P         2.257   2.285   2.427   2.444   2.483   2.714   2.584   2.629   2.881
161   Y        -0.490  -0.495  -0.376  -0.645  -0.677  -0.509  -0.667  -0.661  -0.514
162   N        -0.338  -0.327  -0.287  -0.585  -0.556  -0.489  -0.486  -0.468  -0.409
163   N        -1.616  -1.592  -1.544  -1.517  -1.479  -1.370  -1.149  -1.123  -1.035
164   A        -1.131  -1.125  -1.142  -0.980  -0.963  -1.006  -0.873  -0.860  -0.846
165   M        -1.131  -1.001  -1.118  -0.968  -0.753  -0.980  -0.873  -0.734  -0.822
166   D        -0.912  -0.949  -0.817  -1.048  -1.078  -0.893  -0.873  -0.893  -0.738
167   E         2.257   2.285   2.427   2.021   2.063   2.282   2.584   2.629   2.881
168   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
169   N        -0.914  -0.802  -0.817  -1.128  -0.968  -0.981  -0.857  -0.732  -0.728
170   T        -0.445  -0.427  -0.348  -0.665  -0.642  -0.532  -0.611  -0.589  -0.481
171   E         0.428   0.479   0.384   0.161   0.239   0.098   0.234   0.313   0.144
172   Q        -1.131  -1.120  -1.113  -0.899  -0.878  -0.907  -0.873  -0.858  -0.818
173   N        -0.560  -0.471  -0.619  -0.556  -0.431  -0.623  -0.458  -0.350  -0.508
174   E        -1.131  -1.107  -1.116  -1.148  -1.116  -1.131  -0.873  -0.846  -0.821
175   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
176   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
177   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
178   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
179   E         0.428   0.333   0.337   0.197   0.062   0.067   0.234   0.090   0.070
180   D         0.144   0.188   0.258  -0.257  -0.188  -0.094  -0.181  -0.119  -0.041
181   D         0.277   0.288   0.333  -0.070  -0.039   0.046  -0.043  -0.003   0.058
182   F        -1.616  -1.636  -1.553  -1.323  -1.340  -1.229  -1.149  -1.156  -1.041
183   D         0.848   0.878   1.008   0.355   0.381   0.577   0.372   0.417   0.597
184   A         0.144   0.176   0.244  -0.056   0.009   0.107  -0.181  -0.140  -0.064
185   L        -0.087  -0.143  -0.222  -0.078  -0.166  -0.246  -0.125  -0.201  -0.308
186   S         0.064   0.054   0.173  -0.433  -0.474  -0.305  -0.305  -0.326  -0.174
187   D         0.075   0.014  -0.147   0.305   0.218  -0.019   0.095   0.012  -0.207
188   N        -0.779  -0.796  -0.795  -0.875  -0.941  -0.939  -0.734  -0.752  -0.714
189   F         0.075  -0.009  -0.141   0.366   0.260   0.056   0.095  -0.019  -0.200
190   A        -0.560  -0.653  -0.713  -0.262  -0.376  -0.438  -0.458  -0.564  -0.616
191   N         0.762   0.677   0.520   0.981   0.873   0.651   0.787   0.654   0.384
192   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
193   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
194   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
195   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
196   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
197   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
198   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
199   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
200   V         0.075  -0.050  -0.165   0.289   0.123  -0.051   0.095  -0.073  -0.232
201   N        -0.208  -0.191  -0.241  -0.101  -0.069  -0.140  -0.319  -0.295  -0.352
202   V         0.913   0.927   1.028   0.695   0.710   0.854   0.510   0.524   0.642
203   V         0.428   0.397   0.375   0.256   0.211   0.113   0.234   0.193   0.135
204   I         1.114   1.206   1.184   1.114   1.257   1.198   0.925   1.094   0.979
205   S        -0.294  -0.300  -0.279  -0.683  -0.688  -0.645  -0.458  -0.459  -0.407
206   K         0.762   0.703   0.533   1.038   0.964   0.725   0.787   0.693   0.405
207   E        -0.208  -0.168  -0.230  -0.182  -0.089  -0.223  -0.319  -0.254  -0.328
208   S        -0.779  -0.816  -0.769  -0.775  -0.825  -0.739  -0.734  -0.766  -0.688
209   A        -1.616  -1.589  -1.525  -1.295  -1.249  -1.160  -1.149  -1.121  -1.021
210   S         0.058   0.115   0.210  -0.146  -0.033   0.086  -0.319  -0.242  -0.122
211   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
212   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
213   A         0.428   0.502   0.395   0.429   0.526   0.391   0.234   0.335   0.168
214   V         0.762   0.903   0.590   0.738   0.924   0.506   0.787   0.999   0.498
215   S        -1.131  -1.125  -1.142  -1.095  -1.088  -1.123  -0.873  -0.860  -0.846
216   F         0.428   0.387   0.351   0.454   0.377   0.299   0.234   0.156   0.090
217   E        -0.560  -0.624  -0.710  -0.580  -0.651  -0.784  -0.458  -0.530  -0.613
218   L         2.257   2.285   2.427   2.070   2.104   2.333   2.584   2.629   2.881
219   L         0.326   0.257   0.257   0.174   0.068   0.086   0.106  -0.007  -0.042
220   M        -0.427  -0.474  -0.376  -0.433  -0.520  -0.389  -0.596  -0.641  -0.515
221   N        -0.294  -0.314  -0.291  -0.249  -0.251  -0.214  -0.458  -0.467  -0.416
222   L        -0.208  -0.112  -0.238  -0.192  -0.071  -0.231  -0.319  -0.210  -0.349
223   Q        -0.208  -0.300  -0.277  -0.180  -0.329  -0.337  -0.319  -0.425  -0.391
224   E         1.114   1.093   1.120   0.790   0.749   0.765   0.925   0.870   0.844
225   G         0.428   0.397   0.375   0.496   0.452   0.388   0.234   0.193   0.135
226   S         0.075  -0.027  -0.142   0.096  -0.060  -0.258   0.095  -0.043  -0.201
227   F         1.491   1.498   1.376   1.672   1.689   1.538   1.616   1.624   1.367
228   Y        -0.779  -0.856  -0.809  -0.676  -0.808  -0.753  -0.734  -0.804  -0.726
229   V         0.913   0.896   1.012   0.695   0.653   0.824   0.510   0.458   0.606
230   D         0.762   0.638   0.525   0.870   0.681   0.474   0.787   0.594   0.393
231   S        -0.779  -0.827  -0.800  -0.763  -0.815  -0.745  -0.734  -0.780  -0.718
232   A        -0.208  -0.201  -0.255  -0.138  -0.146  -0.190  -0.319  -0.332  -0.369
233   T        -0.208  -0.246  -0.267  -0.074  -0.117  -0.143  -0.319  -0.361  -0.378
234   P        -0.208  -0.235  -0.267   0.054   0.013  -0.028  -0.319  -0.352  -0.385
235   Y         0.428   0.397   0.375   0.624   0.581   0.523   0.234   0.193   0.135
236   P        -1.616  -1.532  -1.521  -1.288  -1.148  -1.145  -1.149  -1.072  -1.017
237   S        -0.208  -0.099  -0.205  -0.216  -0.037  -0.187  -0.319  -0.168  -0.294
238   V        -0.779  -0.807  -0.761  -0.739  -0.771  -0.699  -0.734  -0.756  -0.680
239   D        -1.264  -1.203  -1.178  -1.223  -1.120  -1.107  -1.011  -0.953  -0.885
240   A        -1.616  -1.550  -1.524  -1.490  -1.384  -1.339  -1.149  -1.088  -1.020
241   A         0.428   0.424   0.359   0.296   0.271   0.151   0.234   0.214   0.103
242   L        -0.208  -0.245  -0.280  -0.260  -0.315  -0.312  -0.319  -0.379  -0.402
243   N        -0.294  -0.339  -0.272  -0.399  -0.448  -0.335  -0.458  -0.497  -0.398
244   Q        -0.294  -0.221  -0.261  -0.506  -0.398  -0.410  -0.458  -0.375  -0.386
245   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
246   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
247   S         0.428   0.398   0.345   0.242   0.186   0.076   0.234   0.177   0.079
248   A         0.075   0.044  -0.130   0.215   0.165  -0.102   0.095   0.054  -0.185
249   E         0.762   0.684   0.535   0.679   0.579   0.371   0.787   0.664   0.409
250   A        -0.208  -0.228  -0.275  -0.178  -0.219  -0.264  -0.319  -0.355  -0.394
251   E         0.075   0.052  -0.128   0.018  -0.019  -0.274   0.095   0.060  -0.182
252   I        -0.912  -0.921  -0.828  -0.723  -0.719  -0.554  -0.873  -0.869  -0.746
253   T        -1.264  -1.235  -1.183  -1.177  -1.167  -1.057  -1.011  -0.980  -0.889
254   R         0.428   0.433   0.376   0.522   0.527   0.423   0.234   0.242   0.137
255   E        -0.912  -0.869  -0.828  -0.954  -0.860  -0.790  -0.873  -0.826  -0.746
256   L        -0.912  -0.946  -0.832  -1.052  -1.069  -0.908  -0.873  -0.891  -0.749
257   V        -1.131  -1.173  -1.155  -0.876  -0.941  -0.901  -0.873  -0.909  -0.857
258   Y         2.257   2.285   2.427   2.491   2.532   2.763   2.584   2.629   2.881
259   H        -0.779  -0.856  -0.809  -0.503  -0.655  -0.614  -0.734  -0.804  -0.726
260   G         2.257   2.285   2.427   2.433   2.473   2.703   2.584   2.629   2.881
261   P         2.257   2.285   2.427   2.444   2.483   2.714   2.584   2.629   2.881
262   P        -0.560  -0.653  -0.713  -0.160  -0.302  -0.398  -0.458  -0.564  -0.616
263   F         2.257   2.285   2.427   2.345   2.391   2.614   2.584   2.629   2.881
264   S        -0.208  -0.302  -0.281  -0.191  -0.304  -0.252  -0.319  -0.428  -0.402
265   N        -1.131  -1.210  -1.192  -1.110  -1.269  -1.307  -0.873  -0.943  -0.892
266   L         2.257   2.285   2.427   2.090   2.132   2.353   2.584   2.629   2.881
267   D         2.257   2.285   2.427   2.297   2.333   2.564   2.584   2.629   2.881
268   E         1.491   1.454   1.377   1.359   1.320   1.236   1.616   1.549   1.370
269   E        -0.427  -0.393  -0.348  -0.766  -0.728  -0.650  -0.596  -0.565  -0.486
270   L         1.491   1.506   1.378   1.401   1.426   1.257   1.616   1.637   1.373
271   Q         2.257   2.285   2.427   2.424   2.468   2.694   2.584   2.629   2.881
272   E        -0.779  -0.854  -0.798  -0.940  -1.023  -0.916  -0.734  -0.802  -0.716
273   S        -0.208  -0.217  -0.268  -0.450  -0.478  -0.581  -0.319  -0.337  -0.384
274   L        -0.294  -0.335  -0.303  -0.388  -0.407  -0.322  -0.458  -0.490  -0.430
275   E         0.762   0.638   0.525   0.740   0.591   0.465   0.787   0.594   0.393
276   A        -1.616  -1.591  -1.527  -1.526  -1.481  -1.388  -1.149  -1.122  -1.022
277   Y         1.491   1.581   1.386   1.814   1.931   1.694   1.616   1.762   1.388
278   L         1.491   1.417   1.360   1.416   1.325   1.257   1.616   1.484   1.336
279   E         0.428   0.407   0.344   0.201   0.167   0.085   0.234   0.184   0.077
280   S         0.762   0.711   0.546   0.748   0.676   0.407   0.787   0.707   0.426
281   R         1.114   1.138   1.150   1.198   1.230   1.227   0.925   0.959   0.906
282   G         1.491   1.454   1.377   1.760   1.716   1.629   1.616   1.549   1.370
283   V         1.114   1.119   1.112   1.114   1.109   1.056   0.925   0.922   0.825
284   N         0.277   0.358   0.325   0.153   0.274   0.249  -0.043   0.072   0.037
285   E        -0.208  -0.228  -0.243  -0.383  -0.410  -0.409  -0.319  -0.346  -0.354
286   E        -1.264  -1.303  -1.197  -1.383  -1.439  -1.286  -1.011  -1.032  -0.899
287   L         1.491   1.417   1.360   1.413   1.324   1.251   1.616   1.484   1.336
288   A         0.075   0.007  -0.125   0.163   0.044  -0.178   0.095  -0.000  -0.179
289   S        -0.208  -0.228  -0.275  -0.484  -0.544  -0.650  -0.319  -0.355  -0.394
290   F         1.491   1.417   1.360   1.633   1.537   1.439   1.616   1.484   1.336
291   I         0.762   0.677   0.520   0.968   0.836   0.586   0.787   0.654   0.384
292   S        -0.912  -0.887  -0.831  -0.874  -0.827  -0.723  -0.873  -0.842  -0.748
293   A        -1.616  -1.566  -1.525  -1.617  -1.567  -1.485  -1.149  -1.102  -1.020
294   Y         0.428   0.336   0.350   0.633   0.492   0.494   0.234   0.095   0.088
295   S         0.075  -0.050  -0.165   0.109  -0.071  -0.274   0.095  -0.073  -0.232
296   E         0.428   0.394   0.362   0.114   0.062  -0.015   0.234   0.187   0.108
297   F        -0.208  -0.245  -0.280  -0.066  -0.131  -0.163  -0.319  -0.379  -0.402
298   K         1.491   1.417   1.360   1.697   1.606   1.536   1.616   1.484   1.336
299   E         2.257   2.285   2.427   2.021   2.063   2.282   2.584   2.629   2.881
300   N        -0.208  -0.246  -0.267  -0.312  -0.368  -0.437  -0.319  -0.361  -0.378
301   N        -0.294  -0.317  -0.285  -0.249  -0.259  -0.191  -0.458  -0.472  -0.408
302   E         1.491   1.417   1.360   1.315   1.219   1.126   1.616   1.484   1.336
303   Y         2.257   2.285   2.427   2.491   2.532   2.763   2.584   2.629   2.881
304   I        -0.779  -0.790  -0.774  -0.658  -0.683  -0.665  -0.734  -0.741  -0.690
305   S        -1.131  -1.070  -1.141  -0.886  -0.785  -0.910  -0.873  -0.809  -0.845
306   W         1.491   1.417   1.360   1.974   1.888   1.831   1.616   1.484   1.336
307   L         2.257   2.285   2.427   2.090   2.132   2.353   2.584   2.629   2.881
308   E        -1.264  -1.243  -1.179  -1.359  -1.325  -1.230  -1.011  -0.987  -0.885
309   K        -0.294  -0.283  -0.278  -0.401  -0.390  -0.371  -0.458  -0.434  -0.400
310   M        -0.427  -0.475  -0.372  -0.439  -0.531  -0.414  -0.596  -0.642  -0.512
311   K        -0.208  -0.240  -0.276  -0.047  -0.109  -0.149  -0.319  -0.373  -0.396
312   K        -0.560  -0.622  -0.692  -0.284  -0.372  -0.512  -0.458  -0.529  -0.593
313   F         1.491   1.417   1.360   1.657   1.567   1.485   1.616   1.484   1.336
314   F         0.144   0.103   0.194  -0.084  -0.177  -0.079  -0.181  -0.250  -0.142
315   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
316   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
317   H        -1.264  -1.261  -1.197  -1.178  -1.163  -1.031  -1.011  -1.000  -0.899
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P40513
Output conservation file - output/P40513
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
