1     M         2.288   2.320   2.420   2.740   2.782   2.965   2.679   2.730   2.947
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     D         2.288   2.320   2.420   2.400   2.446   2.619   2.679   2.730   2.947
4     Y        -0.416  -0.454  -0.522  -0.128  -0.170  -0.319  -0.415  -0.470  -0.552
5     F         2.288   2.320   2.420   2.491   2.540   2.711   2.679   2.730   2.947
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    N         0.903   0.865   0.927   0.858   0.789   0.856   0.616   0.522   0.595
14    I         0.903   0.964   0.992   0.924   1.027   1.057   0.616   0.726   0.736
15    K         0.087   0.015   0.084   0.151   0.033   0.130  -0.158  -0.246  -0.160
16    Q         0.087   0.015   0.084   0.045  -0.052   0.036  -0.158  -0.246  -0.160
17    N        -0.416  -0.457  -0.492  -0.168  -0.203  -0.281  -0.415  -0.474  -0.515
18    Y         1.307   1.364   1.208   1.577   1.665   1.450   1.390   1.483   1.181
19    Y         1.307   1.382   1.219   1.613   1.726   1.497   1.390   1.514   1.202
20    T         0.400   0.317   0.240   0.618   0.492   0.359   0.358   0.218   0.092
21    G         0.903   0.966   1.019   0.924   1.035   1.107   0.616   0.730   0.792
22    N         0.087   0.159   0.100  -0.070   0.067  -0.100  -0.158  -0.053  -0.141
23    F         0.087   0.152   0.141   0.322   0.429   0.414  -0.158  -0.059  -0.071
24    V        -0.605  -0.554  -0.551  -0.663  -0.574  -0.560  -0.673  -0.610  -0.595
25    Q         0.087   0.095   0.102  -0.051  -0.061  -0.049  -0.158  -0.161  -0.144
26    C         0.400   0.474   0.282   0.702   0.795   0.534   0.358   0.472   0.159
27    L         0.087   0.102   0.086  -0.312  -0.261  -0.260  -0.158  -0.150  -0.166
28    Q        -1.611  -1.581  -1.513  -1.596  -1.535  -1.452  -1.189  -1.155  -1.076
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    E         0.087   0.102   0.086  -0.108  -0.089  -0.108  -0.158  -0.150  -0.166
31    I        -1.108  -1.111  -1.096  -1.342  -1.323  -1.255  -0.931  -0.931  -0.900
32    E        -0.605  -0.641  -0.586  -0.678  -0.707  -0.656  -0.673  -0.706  -0.633
33    K        -0.416  -0.454  -0.522  -0.330  -0.391  -0.540  -0.415  -0.470  -0.552
34    F         1.307   1.385   1.213   1.466   1.593   1.282   1.390   1.520   1.190
35    S         0.400   0.493   0.288   0.566   0.714   0.400   0.358   0.500   0.169
36    K         0.087   0.015   0.084   0.140   0.011   0.120  -0.158  -0.246  -0.160
37    V        -0.605  -0.640  -0.589  -0.645  -0.695  -0.604  -0.673  -0.705  -0.637
38    T        -0.605  -0.549  -0.551  -0.645  -0.537  -0.538  -0.673  -0.605  -0.595
39    D         0.087   0.015   0.084  -0.006  -0.137  -0.028  -0.158  -0.246  -0.160
40    N        -0.416  -0.320  -0.490  -0.728  -0.573  -0.836  -0.415  -0.287  -0.511
41    T        -0.605  -0.640  -0.589  -0.539  -0.555  -0.496  -0.673  -0.705  -0.637
42    L        -0.605  -0.632  -0.583  -0.892  -0.964  -0.873  -0.673  -0.697  -0.629
43    L        -0.416  -0.457  -0.490  -0.593  -0.604  -0.657  -0.415  -0.473  -0.511
44    F        -0.605  -0.641  -0.586  -0.568  -0.603  -0.506  -0.673  -0.706  -0.633
45    Y         0.400   0.307   0.246   0.605   0.420   0.304   0.358   0.203   0.101
46    K         0.400   0.474   0.282   0.660   0.764   0.498   0.358   0.472   0.159
47    A        -1.108  -1.026  -1.038  -1.355  -1.251  -1.240  -0.931  -0.837  -0.842
48    K         1.307   1.364   1.208   1.763   1.839   1.619   1.390   1.483   1.181
49    T         0.400   0.299   0.240   0.512   0.333   0.240   0.358   0.193   0.091
50    L        -0.605  -0.632  -0.583  -0.839  -0.817  -0.792  -0.673  -0.697  -0.629
51    L         0.903   0.963   0.998   0.687   0.816   0.810   0.616   0.725   0.747
52    A         2.288   2.320   2.420   2.276   2.275   2.492   2.679   2.730   2.947
53    L         2.288   2.320   2.420   1.954   2.003   2.165   2.679   2.730   2.947
54    G        -0.416  -0.317  -0.460  -0.216  -0.053  -0.320  -0.415  -0.282  -0.473
55    Q         1.307   1.382   1.219   1.493   1.595   1.368   1.390   1.514   1.202
56    Y        -1.108  -1.111  -1.096  -1.154  -1.180  -1.182  -0.931  -0.931  -0.900
57    Q        -1.108  -1.111  -1.096  -1.172  -1.221  -1.161  -0.931  -0.931  -0.900
58    S        -0.416  -0.457  -0.490  -0.398  -0.471  -0.561  -0.415  -0.473  -0.511
59    Q        -1.108  -1.110  -1.077  -0.864  -0.863  -0.831  -0.931  -0.929  -0.881
60    D        -1.108  -1.024  -1.040  -1.185  -1.079  -1.059  -0.931  -0.835  -0.844
61    P        -0.605  -0.546  -0.552  -0.555  -0.510  -0.466  -0.673  -0.602  -0.593
62    T         0.087   0.096   0.116  -0.048  -0.057  -0.016  -0.158  -0.159  -0.124
63    S        -0.611  -0.572  -0.577  -0.575  -0.494  -0.535  -0.663  -0.619  -0.620
64    -         1.064   0.993   1.034   1.143   0.972   1.037   0.938   0.784   0.823
65    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
66    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
67    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
68    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
69    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
70    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
71    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
72    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
73    K        -1.108  -1.110  -1.077  -0.960  -1.000  -0.910  -0.931  -0.929  -0.881
74    L         1.307   1.159   1.160   1.034   0.829   0.827   1.390   1.110   1.084
75    G         0.087   0.168   0.147   0.160   0.295   0.264  -0.158  -0.039  -0.062
76    K        -1.108  -1.113  -1.039  -1.101  -1.142  -1.013  -0.931  -0.932  -0.843
77    V         0.087   0.159   0.100  -0.356  -0.264  -0.333  -0.158  -0.053  -0.141
78    L         0.087   0.014   0.101  -0.354  -0.472  -0.332  -0.158  -0.248  -0.139
79    D        -1.108  -1.111  -1.096  -1.132  -1.137  -1.145  -0.931  -0.931  -0.900
80    L         0.779   0.807   0.901   0.127   0.128   0.297   0.358   0.399   0.537
81    Y         0.087   0.015   0.084   0.328   0.228   0.322  -0.158  -0.246  -0.160
82    V        -1.108  -1.111  -1.096  -1.012  -1.047  -1.014  -0.931  -0.931  -0.900
83    Q        -1.108  -1.111  -1.096  -0.936  -0.921  -0.914  -0.931  -0.931  -0.900
84    F         0.087   0.015   0.084  -0.157  -0.240  -0.169  -0.158  -0.246  -0.160
85    L         0.087   0.015   0.084  -0.410  -0.524  -0.421  -0.158  -0.246  -0.160
86    D        -0.605  -0.632  -0.538  -0.696  -0.738  -0.597  -0.673  -0.697  -0.582
87    -        -0.611  -0.653  -0.604  -0.573  -0.636  -0.598  -0.663  -0.712  -0.652
88    -        -0.611  -0.653  -0.604  -0.504  -0.623  -0.522  -0.663  -0.712  -0.652
89    T         0.087   0.109   0.115   0.105   0.131   0.146  -0.158  -0.142  -0.124
90    K        -1.108  -1.111  -1.096  -0.894  -0.925  -0.863  -0.931  -0.931  -0.900
91    N        -0.416  -0.470  -0.490  -0.278  -0.353  -0.411  -0.415  -0.490  -0.511
92    I         0.087   0.168   0.147  -0.044   0.119   0.027  -0.158  -0.039  -0.062
93    E         0.087   0.108   0.101  -0.025  -0.015  -0.034  -0.158  -0.144  -0.146
94    E        -1.108  -1.111  -1.096  -0.998  -1.011  -1.034  -0.931  -0.931  -0.900
95    L         0.903   0.966   1.019   0.431   0.537   0.606   0.616   0.730   0.792
96    E         1.307   1.159   1.160   1.305   1.059   1.062   1.390   1.110   1.084
97    N        -1.108  -1.111  -1.096  -1.058  -1.093  -1.062  -0.931  -0.931  -0.900
98    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
99    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
100   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
101   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
102   K        -1.611  -1.581  -1.513  -1.365  -1.322  -1.217  -1.189  -1.155  -1.076
103   Q        -1.108  -1.113  -1.039  -0.934  -0.938  -0.830  -0.931  -0.932  -0.843
104   N        -1.108  -1.109  -1.081  -0.912  -0.949  -0.872  -0.931  -0.929  -0.885
105   S        -0.605  -0.632  -0.583  -0.557  -0.604  -0.457  -0.673  -0.697  -0.629
106   P        -0.605  -0.545  -0.549  -0.682  -0.590  -0.645  -0.673  -0.601  -0.593
107   Y         0.087   0.014   0.100   0.188   0.102   0.218  -0.158  -0.248  -0.139
108   E        -0.416  -0.457  -0.490  -0.314  -0.391  -0.410  -0.415  -0.473  -0.511
109   L         1.307   1.159   1.160   1.036   0.835   0.830   1.390   1.110   1.084
110   Y        -0.605  -0.641  -0.586  -0.519  -0.553  -0.467  -0.673  -0.706  -0.633
111   L         0.087   0.015   0.084  -0.442  -0.549  -0.428  -0.158  -0.246  -0.160
112   L         0.087   0.107   0.086  -0.288  -0.244  -0.227  -0.158  -0.145  -0.166
113   A         0.087   0.015   0.084  -0.326  -0.443  -0.317  -0.158  -0.246  -0.160
114   T         0.087   0.014   0.101   0.077  -0.005   0.108  -0.158  -0.248  -0.139
115   A         1.307   1.159   1.160   1.363   1.109   1.158   1.390   1.110   1.084
116   Q        -0.605  -0.633  -0.555  -0.868  -0.884  -0.799  -0.673  -0.699  -0.599
117   A        -0.605  -0.640  -0.589  -0.576  -0.637  -0.544  -0.673  -0.705  -0.637
118   I         0.779   0.806   0.901   0.301   0.326   0.467   0.358   0.398   0.538
119   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
120   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
121   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
122   L        -0.416  -0.465  -0.462  -0.467  -0.575  -0.609  -0.415  -0.484  -0.475
123   G         0.903   0.966   1.019   0.915   1.024   1.097   0.616   0.730   0.792
124   D         0.400   0.300   0.231   0.523   0.367   0.226   0.358   0.194   0.078
125   L        -1.108  -1.111  -1.096  -1.095  -1.139  -1.141  -0.931  -0.931  -0.900
126   D         0.555   0.690   0.378   0.737   0.923   0.468   0.595   0.799   0.313
127   K        -0.491  -0.366  -0.478  -0.514  -0.315  -0.476  -0.542  -0.379  -0.501
128   S         0.986   1.081   1.053   0.796   0.919   0.890   0.784   0.959   0.865
129   L         0.986   1.081   1.067   0.560   0.713   0.679   0.784   0.961   0.892
130   E        -1.515  -1.515  -1.477  -1.430  -1.450  -1.372  -1.110  -1.105  -1.047
131   T        -0.491  -0.366  -0.478  -0.749  -0.574  -0.703  -0.542  -0.379  -0.505
132   C         0.208   0.324   0.183  -0.041   0.111  -0.068   0.027   0.207  -0.009
133   V        -0.922  -0.985  -1.022  -0.654  -0.784  -0.843  -0.731  -0.803  -0.825
134   E        -0.922  -0.985  -1.022  -0.719  -0.800  -0.848  -0.731  -0.803  -0.825
135   G         0.823   0.846   0.933   0.848   0.883   1.017   0.451   0.483   0.607
136   I         2.288   2.320   2.420   2.475   2.517   2.695   2.679   2.730   2.947
137   D         2.288   2.320   2.420   2.398   2.439   2.616   2.679   2.730   2.947
138   N         0.823   0.844   0.912   0.600   0.629   0.722   0.451   0.477   0.563
139   D        -0.008   0.006   0.067   0.008   0.032   0.139  -0.292  -0.271  -0.190
140   E         0.823   0.843   0.922   0.560   0.587   0.695   0.451   0.477   0.583
141   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
142   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
143   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
144   A        -1.515  -1.357  -1.466  -1.162  -0.851  -1.121  -1.110  -0.954  -1.038
145   E        -1.515  -1.430  -1.450  -1.088  -0.997  -0.967  -1.110  -1.026  -1.024
146   G         0.555   0.698   0.337   0.915   1.116   0.587   0.595   0.811   0.247
147   T        -1.084  -1.131  -1.073  -1.003  -1.045  -0.960  -0.921  -0.956  -0.879
148   T        -0.491  -0.518  -0.515  -0.610  -0.632  -0.599  -0.542  -0.563  -0.552
149   E         1.395   1.495   1.272   1.468   1.600   1.306   1.542   1.707   1.306
150   L        -0.491  -0.435  -0.532  -0.847  -0.799  -0.843  -0.542  -0.495  -0.575
151   L        -0.060  -0.052   0.031  -0.466  -0.416  -0.305  -0.352  -0.345  -0.239
152   L         1.395   1.330   1.236   1.107   1.013   0.866   1.542   1.424   1.236
153   L         0.208   0.325   0.198  -0.147   0.027  -0.143   0.027   0.209   0.019
154   A        -0.491  -0.601  -0.540  -0.816  -0.956  -0.853  -0.542  -0.653  -0.578
155   I         0.103   0.017   0.105   0.077  -0.070   0.079  -0.163  -0.257  -0.142
156   E        -0.491  -0.602  -0.517  -0.320  -0.415  -0.297  -0.542  -0.654  -0.554
157   V        -0.060   0.034   0.079  -0.340  -0.138  -0.095  -0.352  -0.211  -0.164
158   A        -0.491  -0.520  -0.515  -0.517  -0.598  -0.598  -0.542  -0.565  -0.551
159   L         1.395   1.235   1.252   1.150   0.937   0.968   1.542   1.252   1.267
160   L        -0.491  -0.601  -0.540  -0.846  -1.012  -0.920  -0.542  -0.653  -0.578
161   N        -0.654  -0.589  -0.588  -0.681  -0.559  -0.574  -0.731  -0.654  -0.637
162   N         0.986   1.081   1.067   1.034   1.204   1.158   0.784   0.961   0.892
163   N        -0.491  -0.520  -0.507  -0.336  -0.358  -0.337  -0.542  -0.578  -0.547
164   V        -1.946  -1.907  -1.851  -1.711  -1.618  -1.569  -1.299  -1.262  -1.191
165   S        -1.084  -1.131  -1.044  -0.996  -1.058  -0.936  -0.921  -0.955  -0.853
166   T        -1.084  -1.053  -1.041  -1.155  -1.171  -1.110  -0.921  -0.882  -0.849
167   A         2.288   2.320   2.420   2.235   2.240   2.450   2.679   2.730   2.947
168   S        -0.922  -0.985  -1.022  -0.570  -0.625  -0.698  -0.731  -0.803  -0.825
169   T         0.802   0.862   0.928   0.634   0.748   0.833   0.406   0.516   0.597
170   I        -1.084  -1.136  -1.041  -0.870  -1.031  -0.850  -0.921  -0.960  -0.850
171   F        -0.491  -0.601  -0.540  -0.567  -0.684  -0.617  -0.542  -0.653  -0.578
172   D        -1.515  -1.520  -1.481  -1.535  -1.498  -1.498  -1.110  -1.110  -1.051
173   N         0.555   0.335   0.301   0.808   0.499   0.420   0.595   0.255   0.190
174   Y        -0.491  -0.462  -0.506  -0.428  -0.360  -0.506  -0.542  -0.494  -0.546
175   T        -1.515  -1.523  -1.485  -1.209  -1.235  -1.166  -1.110  -1.112  -1.054
176   N        -1.084  -0.973  -1.033  -0.823  -0.607  -0.759  -0.921  -0.804  -0.843
177   A        -0.611  -0.597  -0.604  -0.748  -0.726  -0.818  -0.663  -0.642  -0.652
178   I        -0.611  -0.597  -0.604  -0.345  -0.318  -0.385  -0.663  -0.642  -0.652
179   E         0.220   0.253   0.185   0.157   0.210   0.083   0.080   0.129   0.003
180   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
181   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
182   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
183   S         0.555   0.335   0.301   0.711   0.381   0.272   0.595   0.255   0.190
184   G        -0.491  -0.435  -0.507  -0.543  -0.491  -0.541  -0.542  -0.486  -0.547
185   D        -0.491  -0.450  -0.489  -0.328  -0.275  -0.335  -0.542  -0.480  -0.515
186   N         1.395   1.480   1.267   1.566   1.674   1.403   1.542   1.681   1.297
187   E        -0.491  -0.548  -0.524  -0.542  -0.620  -0.580  -0.542  -0.607  -0.567
188   M        -0.491  -0.549  -0.507  -0.509  -0.618  -0.548  -0.542  -0.608  -0.547
189   I        -0.223  -0.365  -0.398  -0.042  -0.332  -0.390  -0.163  -0.355  -0.392
190   L        -0.491  -0.457  -0.507  -0.508  -0.397  -0.528  -0.542  -0.491  -0.543
191   N         0.208   0.139   0.199   0.162   0.056   0.108   0.027  -0.052   0.020
192   L         0.986   1.081   1.067   0.557   0.705   0.676   0.784   0.961   0.892
193   A         0.986   1.081   1.067   0.622   0.768   0.719   0.784   0.961   0.892
194   E         1.395   1.235   1.252   1.472   1.250   1.282   1.542   1.252   1.267
195   S         1.395   1.235   1.252   1.560   1.324   1.349   1.542   1.252   1.267
196   Y         0.103   0.017   0.105   0.396   0.300   0.430  -0.163  -0.257  -0.142
197   I         0.208   0.195   0.160   0.224   0.169   0.097   0.027  -0.035  -0.052
198   K        -1.084  -1.139  -1.079  -1.311  -1.384  -1.255  -0.921  -0.962  -0.885
199   F        -0.491  -0.601  -0.540  -0.388  -0.513  -0.473  -0.542  -0.653  -0.578
200   A        -0.654  -0.589  -0.588  -0.579  -0.450  -0.455  -0.731  -0.654  -0.637
201   T        -0.922  -0.990  -0.970  -0.840  -1.019  -0.983  -0.731  -0.808  -0.771
202   N         0.802   0.813   0.919   0.731   0.749   0.913   0.406   0.412   0.576
203   K        -0.491  -0.347  -0.478  -0.351  -0.116  -0.327  -0.542  -0.361  -0.507
204   E        -0.060   0.026   0.070  -0.288  -0.130  -0.091  -0.352  -0.222  -0.179
205   T        -0.491  -0.465  -0.508  -0.421  -0.370  -0.432  -0.542  -0.497  -0.542
206   A        -1.515  -1.523  -1.498  -1.164  -1.110  -1.127  -1.110  -1.112  -1.065
207   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
208   T        -1.515  -1.528  -1.450  -1.115  -1.082  -1.006  -1.110  -1.116  -1.024
209   S         0.208   0.211   0.173   0.242   0.289   0.199   0.027   0.052  -0.020
210   N        -0.060  -0.052   0.031  -0.273  -0.298  -0.164  -0.352  -0.345  -0.239
211   F         0.802   0.813   0.911   0.781   0.809   0.951   0.406   0.413   0.560
212   Y         2.288   2.320   2.420   2.559   2.609   2.781   2.679   2.730   2.947
213   Y        -0.922  -0.986  -0.995  -0.442  -0.545  -0.530  -0.731  -0.804  -0.797
214   Y         0.802   0.864   0.920   0.781   0.902   0.967   0.406   0.520   0.579
215   E         0.986   1.081   1.067   0.838   0.994   0.955   0.784   0.961   0.892
216   E         1.395   1.235   1.252   1.468   1.239   1.274   1.542   1.252   1.267
217   L         1.395   1.481   1.262   1.151   1.270   0.985   1.542   1.684   1.286
218   S        -0.060  -0.013   0.056  -0.533  -0.429  -0.351  -0.352  -0.284  -0.204
219   Q         0.986   1.081   1.067   0.985   1.152   1.103   0.784   0.961   0.892
220   T        -0.922  -0.985  -1.022  -0.599  -0.689  -0.758  -0.731  -0.803  -0.825
221   F        -0.491  -0.601  -0.540  -0.302  -0.432  -0.340  -0.542  -0.653  -0.578
222   P        -0.491  -0.601  -0.540  -0.195  -0.366  -0.294  -0.542  -0.653  -0.578
223   T        -0.491  -0.520  -0.489  -0.384  -0.393  -0.352  -0.542  -0.565  -0.515
224   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
228   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
229   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
230   W         0.087   0.015   0.084   0.388   0.288   0.384  -0.158  -0.246  -0.160
231   K         0.555   0.335   0.301   0.847   0.547   0.508   0.595   0.255   0.190
232   T        -0.654  -0.694  -0.575  -0.530  -0.527  -0.382  -0.731  -0.760  -0.622
233   Q         0.802   0.862   0.928   0.253   0.345   0.440   0.406   0.516   0.597
234   L         0.208   0.211   0.173  -0.163  -0.129  -0.190   0.027   0.052  -0.020
235   G         0.208   0.211   0.173   0.371   0.394   0.323   0.027   0.052  -0.020
236   L         0.986   0.884   0.976   0.540   0.379   0.509   0.784   0.562   0.701
237   L        -0.060  -0.052   0.031  -0.602  -0.606  -0.470  -0.352  -0.345  -0.239
238   N        -0.491  -0.548  -0.524  -0.554  -0.693  -0.663  -0.542  -0.607  -0.567
239   L         0.555   0.335   0.301   0.310  -0.011  -0.080   0.595   0.255   0.190
240   H        -0.654  -0.581  -0.586  -0.553  -0.476  -0.445  -0.731  -0.648  -0.635
241   L         0.986   0.884   0.976   0.560   0.404   0.537   0.784   0.562   0.701
242   Q         1.395   1.330   1.236   1.665   1.593   1.488   1.542   1.424   1.236
243   Q         0.802   0.862   0.928   0.253   0.345   0.440   0.406   0.516   0.597
244   R        -0.491  -0.366  -0.478  -0.259  -0.057  -0.196  -0.542  -0.379  -0.501
245   N        -0.060  -0.052   0.030   0.176   0.200   0.316  -0.352  -0.346  -0.240
246   I        -1.084  -0.993  -1.021  -0.968  -0.806  -0.876  -0.921  -0.830  -0.832
247   A        -0.922  -0.986  -0.995  -0.527  -0.671  -0.706  -0.731  -0.804  -0.797
248   E         2.288   2.320   2.420   2.290   2.331   2.507   2.679   2.730   2.947
249   A         1.395   1.473   1.254   1.417   1.487   1.230   1.542   1.670   1.271
250   Q         0.986   0.937   0.983   0.983   0.890   0.941   0.784   0.671   0.716
251   G        -0.491  -0.403  -0.498  -0.602  -0.503  -0.610  -0.542  -0.443  -0.538
252   I        -0.491  -0.601  -0.540  -0.665  -0.816  -0.752  -0.542  -0.653  -0.578
253   V         0.208   0.324   0.183  -0.140   0.030  -0.153   0.027   0.207  -0.009
254   E        -0.491  -0.510  -0.482  -0.581  -0.602  -0.584  -0.542  -0.556  -0.518
255   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
256   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
257   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
258   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
259   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
260   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
261   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
262   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
263   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
264   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
265   Q         0.400   0.349   0.288   0.611   0.534   0.430   0.358   0.271   0.169
266   K        -1.515  -1.515  -1.477  -1.362  -1.381  -1.318  -1.110  -1.105  -1.047
267   E        -1.084  -1.139  -1.079  -1.229  -1.335  -1.263  -0.921  -0.962  -0.885
268   N        -1.515  -1.426  -1.450  -1.392  -1.254  -1.294  -1.110  -1.023  -1.024
269   A        -0.654  -0.661  -0.578  -1.052  -1.027  -0.879  -0.731  -0.726  -0.626
270   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
271   V        -1.084  -1.137  -1.076  -0.955  -1.088  -0.971  -0.921  -0.960  -0.882
272   L        -1.084  -0.973  -1.056  -1.051  -0.788  -0.966  -0.921  -0.804  -0.864
273   Y        -0.922  -0.985  -1.022  -0.487  -0.586  -0.651  -0.731  -0.803  -0.825
274   K         0.103   0.073   0.109   0.017  -0.008   0.058  -0.163  -0.188  -0.135
275   P        -0.060  -0.012   0.022  -0.010   0.054   0.089  -0.352  -0.283  -0.252
276   T         0.103   0.158   0.158   0.027   0.114   0.127  -0.163  -0.095  -0.076
277   F         0.208   0.179   0.148   0.136   0.014  -0.044   0.027  -0.054  -0.071
278   L         0.986   0.990   0.975   0.560   0.570   0.534   0.784   0.780   0.698
279   A         1.395   1.235   1.252   1.476   1.243   1.328   1.542   1.252   1.267
280   N         1.395   1.235   1.252   1.587   1.359   1.376   1.542   1.252   1.267
281   Q         0.802   0.812   0.912   0.628   0.642   0.795   0.406   0.411   0.563
282   I         1.395   1.330   1.236   1.590   1.492   1.317   1.542   1.424   1.236
283   T         0.986   0.884   0.976   1.029   0.840   0.982   0.784   0.562   0.701
284   L        -1.515  -1.523  -1.485  -1.246  -1.205  -1.101  -1.110  -1.112  -1.054
285   A        -1.084  -1.139  -1.079  -1.063  -1.127  -1.025  -0.921  -0.962  -0.885
286   L        -1.084  -1.043  -1.041  -1.154  -1.129  -1.086  -0.921  -0.873  -0.850
287   M        -0.491  -0.602  -0.517  -0.597  -0.728  -0.599  -0.542  -0.654  -0.554
288   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
289   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
290   Q        -1.515  -1.437  -1.452  -1.376  -1.237  -1.278  -1.110  -1.032  -1.026
291   G         2.288   2.320   2.420   2.536   2.576   2.757   2.679   2.730   2.947
292   L        -1.515  -1.528  -1.450  -1.609  -1.618  -1.528  -1.110  -1.116  -1.024
293   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
294   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
295   D         0.103   0.182   0.134   0.014   0.134   0.078  -0.163  -0.058  -0.104
296   T        -0.654  -0.661  -0.570  -0.737  -0.737  -0.590  -0.731  -0.726  -0.620
297   E        -0.491  -0.555  -0.493  -0.619  -0.726  -0.622  -0.542  -0.615  -0.531
298   D         1.395   1.480   1.267   1.468   1.580   1.299   1.542   1.681   1.297
299   L         1.395   1.330   1.236   1.166   1.094   0.972   1.542   1.424   1.236
300   T        -0.654  -0.587  -0.587  -0.774  -0.652  -0.628  -0.731  -0.652  -0.636
301   N        -0.922  -0.986  -0.963  -0.756  -0.884  -0.847  -0.731  -0.804  -0.762
302   Q         0.555   0.546   0.358   0.644   0.616   0.339   0.595   0.577   0.280
303   L         2.288   2.320   2.420   1.957   2.005   2.168   2.679   2.730   2.947
304   V        -0.922  -0.849  -0.925  -0.713  -0.602  -0.728  -0.731  -0.647  -0.721
305   K         0.103   0.159   0.147   0.103   0.176   0.206  -0.163  -0.094  -0.089
306   L        -0.491  -0.540  -0.487  -0.886  -0.960  -0.852  -0.542  -0.599  -0.524
307   D         0.555   0.690   0.378   0.773   0.951   0.523   0.595   0.799   0.313
308   H        -0.491  -0.423  -0.481  -0.251  -0.209  -0.249  -0.542  -0.474  -0.517
309   E        -0.654  -0.694  -0.568  -0.759  -0.777  -0.626  -0.731  -0.760  -0.619
310   H         2.288   2.320   2.420   2.705   2.744   2.929   2.679   2.730   2.947
311   A        -0.922  -0.734  -0.944  -0.488  -0.179  -0.554  -0.731  -0.511  -0.742
312   F         0.103   0.018   0.124  -0.217  -0.277  -0.142  -0.163  -0.257  -0.118
313   I        -1.515  -1.464  -1.448  -1.398  -1.317  -1.267  -1.110  -1.061  -1.022
314   K        -0.223  -0.371  -0.412   0.012  -0.229  -0.293  -0.163  -0.362  -0.411
315   H        -1.084  -0.994  -1.019  -1.039  -0.932  -0.933  -0.921  -0.831  -0.831
316   H        -1.084  -0.973  -1.056  -1.052  -0.980  -1.022  -0.921  -0.804  -0.864
317   Q        -1.515  -1.357  -1.466  -1.683  -1.421  -1.631  -1.110  -0.954  -1.038
318   E         1.395   1.481   1.262   1.399   1.522   1.171   1.542   1.684   1.286
319   I        -0.922  -0.740  -0.945  -0.795  -0.474  -0.863  -0.731  -0.517  -0.743
320   D        -0.491  -0.460  -0.464  -0.404  -0.318  -0.361  -0.542  -0.491  -0.497
321   A        -0.491  -0.521  -0.506  -0.549  -0.637  -0.591  -0.542  -0.580  -0.547
322   K        -0.491  -0.448  -0.498  -0.662  -0.683  -0.676  -0.542  -0.508  -0.534
323   F         2.288   2.320   2.420   2.503   2.557   2.723   2.679   2.730   2.947
324   D         2.288   2.320   2.420   2.379   2.413   2.597   2.679   2.730   2.947
325   E        -0.491  -0.448  -0.498  -0.544  -0.489  -0.546  -0.542  -0.508  -0.534
326   L        -0.223  -0.366  -0.404  -0.042  -0.284  -0.403  -0.163  -0.356  -0.400
327   V         1.395   1.330   1.236   1.627   1.516   1.389   1.542   1.424   1.236
328   R        -1.515  -1.464  -1.448  -1.318  -1.323  -1.225  -1.110  -1.061  -1.022
329   K         2.288   2.320   2.420   2.402   2.447   2.621   2.679   2.730   2.947
330   Y         2.288   2.320   2.420   2.559   2.609   2.781   2.679   2.730   2.947
331   D         0.025   0.039   0.099  -0.196  -0.178  -0.109  -0.222  -0.203  -0.133
332   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
333   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
334   T        -0.729  -0.715  -0.623  -0.841  -0.814  -0.683  -0.802  -0.782  -0.674
335   S        -0.922  -0.895  -0.915  -0.721  -0.675  -0.722  -0.731  -0.705  -0.710
336   N        -0.491  -0.350  -0.476  -0.532  -0.352  -0.487  -0.542  -0.361  -0.502
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P40509
Output conservation file - output/P40509
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
