1     M         1.328   1.347   1.421   1.492   1.511   1.632   1.424   1.454   1.569
2     S        -0.052  -0.120  -0.387   0.073  -0.025  -0.422  -0.018  -0.116  -0.480
3     F        -0.686  -0.783  -0.958  -0.553  -0.692  -0.996  -0.572  -0.690  -0.870
4     L         0.087   0.152   0.205  -0.252  -0.133  -0.082  -0.240  -0.132  -0.082
5     Q         1.328   1.347   1.421   1.267   1.300   1.420   1.424   1.454   1.569
6     N         0.483   0.347   0.280   0.440   0.246   0.104   0.438   0.212   0.057
7     F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     I        -0.465  -0.349  -0.456  -0.697  -0.529  -0.661  -0.604  -0.451  -0.575
10    S        -0.556  -0.605  -0.513  -0.757  -0.809  -0.672  -0.749  -0.792  -0.656
11    P         0.047   0.106   0.188  -0.222  -0.117  -0.005  -0.314  -0.216  -0.114
12    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    Q        -1.067  -1.146  -1.032  -1.034  -1.142  -0.993  -1.039  -1.107  -0.949
14    T        -0.702  -0.685  -0.544  -0.945  -0.921  -0.710  -0.905  -0.883  -0.692
15    I        -1.475  -1.534  -1.433  -1.469  -1.550  -1.427  -1.238  -1.277  -1.125
16    R         0.273   0.227   0.208   0.314   0.239   0.165   0.093   0.004  -0.076
17    S         0.087   0.067   0.182  -0.155  -0.207  -0.026  -0.240  -0.290  -0.125
18    T        -0.052  -0.199  -0.424   0.110  -0.087  -0.419  -0.018  -0.217  -0.530
19    R        -0.052  -0.199  -0.424   0.194   0.006  -0.371  -0.018  -0.217  -0.530
20    G        -0.361  -0.446  -0.479  -0.277  -0.431  -0.501  -0.461  -0.585  -0.612
21    F         1.328   1.347   1.421   1.267   1.293   1.420   1.424   1.454   1.569
22    K         0.273   0.196   0.206   0.308   0.173   0.158   0.093  -0.052  -0.080
23    W        -1.150  -1.183  -1.036  -1.119  -1.170  -0.979  -1.127  -1.147  -0.954
24    N        -1.150  -1.139  -1.034  -1.165  -1.140  -0.992  -1.127  -1.112  -0.953
25    T        -1.475  -1.488  -1.420  -1.383  -1.397  -1.298  -1.238  -1.240  -1.114
26    A        -1.027  -1.034  -1.012  -1.023  -1.044  -0.971  -1.016  -1.017  -0.932
27    N        -0.454  -0.439  -0.494  -0.516  -0.496  -0.616  -0.563  -0.544  -0.626
28    A        -0.651  -0.619  -0.534  -0.899  -0.855  -0.701  -0.847  -0.808  -0.679
29    A        -1.171  -1.129  -1.056  -1.192  -1.132  -1.052  -1.131  -1.083  -0.972
30    N         0.066   0.083   0.195  -0.277  -0.256  -0.075  -0.279  -0.259  -0.100
31    N        -1.171  -1.129  -1.056  -1.226  -1.168  -1.066  -1.131  -1.083  -0.972
32    A        -1.171  -1.129  -1.056  -1.099  -1.047  -0.913  -1.131  -1.083  -0.972
33    G        -0.651  -0.605  -0.532  -0.771  -0.709  -0.580  -0.847  -0.793  -0.678
34    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
45    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
46    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
47    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
48    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
49    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
50    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
57    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
58    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
59    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
60    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
61    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
62    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
63    D        -1.171  -1.148  -1.046  -1.272  -1.243  -1.071  -1.131  -1.104  -0.963
64    F        -1.171  -1.164  -1.052  -1.240  -1.236  -1.079  -1.131  -1.121  -0.968
65    T         0.389   0.422   0.261   0.281   0.328   0.059   0.288   0.337   0.023
66    N        -0.651  -0.634  -0.538  -0.895  -0.869  -0.701  -0.847  -0.825  -0.685
67    N        -1.691  -1.658  -1.460  -1.844  -1.801  -1.512  -1.415  -1.379  -1.147
68    P        -1.171  -1.164  -1.052  -1.353  -1.354  -1.210  -1.131  -1.121  -0.968
69    V        -0.651  -0.619  -0.534  -0.940  -0.895  -0.746  -0.847  -0.808  -0.679
70    N        -0.454  -0.459  -0.490  -0.609  -0.624  -0.702  -0.563  -0.573  -0.621
71    G        -1.171  -1.156  -1.030  -1.253  -1.239  -1.060  -1.131  -1.112  -0.947
72    Y        -1.171  -1.129  -1.056  -1.240  -1.183  -1.081  -1.131  -1.083  -0.972
73    N        -0.454  -0.446  -0.507  -0.606  -0.600  -0.727  -0.563  -0.555  -0.644
74    E        -0.454  -0.425  -0.478  -0.413  -0.374  -0.514  -0.563  -0.526  -0.605
75    S         0.389   0.422   0.261   0.276   0.322   0.048   0.288   0.337   0.023
76    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
77    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
78    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
79    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
80    M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
81    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
82    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
83    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
84    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
85    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
86    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
87    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
88    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
89    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
90    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
91    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
92    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
93    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
94    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
95    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
96    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
97    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
98    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
99    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
100   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
101   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
102   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
103   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
104   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
105   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
106   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
107   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
108   V        -0.454  -0.446  -0.507  -0.352  -0.344  -0.451  -0.563  -0.555  -0.644
109   T        -0.454  -0.446  -0.507  -0.554  -0.548  -0.713  -0.563  -0.555  -0.644
110   D         0.389   0.406   0.266   0.468   0.490   0.222   0.288   0.310   0.032
111   F        -0.454  -0.446  -0.507  -0.516  -0.509  -0.641  -0.563  -0.555  -0.644
112   N        -0.454  -0.446  -0.507  -0.596  -0.590  -0.712  -0.563  -0.555  -0.644
113   Y        -0.454  -0.446  -0.507  -0.331  -0.325  -0.464  -0.563  -0.555  -0.644
114   T         0.066   0.083   0.195  -0.207  -0.185  -0.013  -0.279  -0.259  -0.100
115   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
116   S        -0.454  -0.446  -0.507  -0.497  -0.490  -0.609  -0.563  -0.555  -0.644
117   H         0.066   0.083   0.195   0.010   0.030   0.196  -0.279  -0.259  -0.100
118   Q         1.328   1.347   1.421   1.260   1.289   1.414   1.424   1.454   1.569
119   K        -0.651  -0.634  -0.538  -0.736  -0.715  -0.559  -0.847  -0.825  -0.685
120   P         0.066   0.083   0.195  -0.182  -0.161   0.016  -0.279  -0.259  -0.100
121   F        -0.651  -0.634  -0.538  -0.883  -0.860  -0.683  -0.847  -0.825  -0.685
122   L        -0.651  -0.632  -0.520  -0.920  -0.896  -0.726  -0.847  -0.822  -0.663
123   Q         0.066   0.083   0.195  -0.271  -0.249  -0.074  -0.279  -0.259  -0.100
124   P        -0.651  -0.634  -0.538  -0.946  -0.926  -0.770  -0.847  -0.825  -0.685
125   Q        -0.651  -0.634  -0.538  -0.808  -0.782  -0.649  -0.847  -0.825  -0.685
126   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
127   G         1.328   1.347   1.421   1.383   1.402   1.529   1.424   1.454   1.569
128   T        -1.475  -1.534  -1.433  -1.399  -1.484  -1.340  -1.238  -1.277  -1.125
129   T        -1.922  -1.927  -1.766  -1.770  -1.776  -1.543  -1.460  -1.451  -1.247
130   V        -0.361  -0.432  -0.479  -0.295  -0.422  -0.490  -0.461  -0.574  -0.612
131   T        -1.027  -1.038  -1.002  -1.079  -1.089  -1.016  -1.016  -1.015  -0.923
132   T        -0.947  -1.024  -0.995  -0.908  -1.016  -0.973  -0.905  -0.981  -0.915
133   H         0.621   0.589   0.342   0.826   0.790   0.404   0.648   0.599   0.168
134   Q        -0.696  -0.675  -0.534  -0.820  -0.793  -0.578  -0.894  -0.871  -0.680
135   D        -0.361  -0.432  -0.479  -0.321  -0.450  -0.570  -0.461  -0.574  -0.612
136   I         0.028   0.065   0.189  -0.329  -0.286  -0.081  -0.350  -0.294  -0.112
137   K         0.273   0.369   0.275   0.314   0.468   0.288   0.093   0.250   0.047
138   Q        -0.686  -0.524  -0.913  -0.475  -0.257  -0.818  -0.572  -0.381  -0.819
139   I         0.087   0.152   0.205  -0.027   0.077   0.139  -0.240  -0.132  -0.082
140   V         0.087   0.152   0.205  -0.061   0.041   0.107  -0.240  -0.132  -0.082
141   E         0.621   0.622   0.347   0.706   0.708   0.330   0.648   0.648   0.177
142   M        -1.272  -1.225  -1.051  -1.280  -1.229  -0.971  -1.238  -1.186  -0.968
143   T         1.328   1.347   1.421   1.299   1.323   1.450   1.424   1.454   1.569
144   L         1.328   1.347   1.421   1.146   1.173   1.306   1.424   1.454   1.569
145   G         1.328   1.347   1.421   1.408   1.432   1.553   1.424   1.454   1.569
146   S        -0.052  -0.096  -0.406   0.096   0.044  -0.401  -0.018  -0.077  -0.507
147   E        -1.150  -1.052  -1.015  -1.093  -0.938  -0.893  -1.127  -1.014  -0.932
148   G        -0.499  -0.421  -0.473  -0.590  -0.476  -0.532  -0.683  -0.579  -0.604
149   V         0.066   0.083   0.195  -0.068  -0.046   0.123  -0.279  -0.259  -0.100
150   L         1.328   1.347   1.421   1.146   1.173   1.306   1.424   1.454   1.569
151   N        -1.475  -1.534  -1.433  -1.307  -1.365  -1.212  -1.238  -1.277  -1.125
152   Q        -0.052  -0.199  -0.424   0.107  -0.086  -0.438  -0.018  -0.217  -0.530
153   A         0.621   0.589   0.342   0.756   0.712   0.357   0.648   0.599   0.168
154   V         1.328   1.347   1.421   1.347   1.373   1.496   1.424   1.454   1.569
155   K         1.328   1.347   1.421   1.387   1.410   1.533   1.424   1.454   1.569
156   L         1.328   1.347   1.421   1.146   1.173   1.306   1.424   1.454   1.569
157   P         1.328   1.347   1.421   1.299   1.330   1.450   1.424   1.454   1.569
158   R        -1.150  -1.119  -1.029  -1.122  -1.097  -0.957  -1.127  -1.102  -0.949
159   G         0.273   0.351   0.292   0.325   0.442   0.329   0.093   0.219   0.079
160   E         1.328   1.347   1.421   1.304   1.328   1.456   1.424   1.454   1.569
161   D         0.273   0.342   0.258   0.275   0.391   0.204   0.093   0.203   0.016
162   E        -1.150  -1.111  -1.031  -1.280  -1.259  -1.105  -1.127  -1.089  -0.951
163   N        -0.052  -0.033  -0.385   0.096   0.127  -0.372  -0.018   0.007  -0.477
164   E         1.328   1.347   1.421   1.304   1.328   1.456   1.424   1.454   1.569
165   W         1.328   1.347   1.421   1.546   1.572   1.683   1.424   1.454   1.569
166   L        -0.361  -0.339  -0.463  -0.467  -0.467  -0.576  -0.461  -0.459  -0.593
167   A         1.328   1.347   1.421   1.360   1.380   1.508   1.424   1.454   1.569
168   V        -0.361  -0.401  -0.444  -0.278  -0.315  -0.382  -0.461  -0.498  -0.559
169   H         0.273   0.196   0.206   0.323   0.181   0.138   0.093  -0.052  -0.080
170   C        -1.150  -1.153  -1.034  -1.006  -1.030  -0.850  -1.127  -1.123  -0.953
171   V         0.621   0.507   0.337   0.764   0.623   0.390   0.648   0.472   0.159
172   D         1.328   1.347   1.421   1.390   1.426   1.536   1.424   1.454   1.569
173   F         1.328   1.347   1.421   1.267   1.293   1.420   1.424   1.454   1.569
174   Y         1.328   1.347   1.421   1.395   1.415   1.541   1.424   1.454   1.569
175   N         0.621   0.507   0.337   0.674   0.533   0.264   0.648   0.472   0.159
176   Q         1.328   1.347   1.421   1.307   1.342   1.458   1.424   1.454   1.569
177   I         0.621   0.622   0.347   0.751   0.756   0.360   0.648   0.648   0.177
178   N         1.328   1.347   1.421   1.286   1.320   1.438   1.424   1.454   1.569
179   M         0.621   0.589   0.342   0.859   0.810   0.403   0.648   0.599   0.168
180   L         1.328   1.347   1.421   1.146   1.173   1.306   1.424   1.454   1.569
181   Y         1.328   1.347   1.421   1.395   1.415   1.541   1.424   1.454   1.569
182   G         0.621   0.622   0.347   0.794   0.795   0.385   0.648   0.648   0.177
183   S        -0.702  -0.656  -0.525  -0.892  -0.832  -0.634  -0.905  -0.849  -0.668
184   I         1.328   1.347   1.421   1.355   1.384   1.503   1.424   1.454   1.569
185   T         1.328   1.347   1.421   1.299   1.323   1.450   1.424   1.454   1.569
186   E         0.621   0.622   0.347   0.691   0.691   0.292   0.648   0.648   0.177
187   F         1.328   1.347   1.421   1.267   1.293   1.420   1.424   1.454   1.569
188   C         1.328   1.347   1.421   1.520   1.547   1.659   1.424   1.454   1.569
189   S         0.621   0.507   0.337   0.672   0.528   0.261   0.648   0.472   0.159
190   P         0.621   0.507   0.337   0.697   0.554   0.299   0.648   0.472   0.159
191   Q        -0.499  -0.446  -0.482  -0.579  -0.523  -0.519  -0.683  -0.633  -0.620
192   T         0.273   0.210   0.210   0.186   0.068   0.032   0.093  -0.026  -0.073
193   C         1.328   1.347   1.421   1.520   1.547   1.659   1.424   1.454   1.569
194   P         1.328   1.347   1.421   1.299   1.330   1.450   1.424   1.454   1.569
195   R        -0.052  -0.199  -0.424   0.184  -0.008  -0.395  -0.018  -0.217  -0.530
196   M         1.328   1.347   1.421   1.492   1.511   1.632   1.424   1.454   1.569
197   I        -0.686  -0.827  -0.966  -0.439  -0.645  -0.887  -0.572  -0.739  -0.878
198   A         1.328   1.347   1.421   1.360   1.380   1.508   1.424   1.454   1.569
199   T         0.621   0.507   0.337   0.704   0.558   0.316   0.648   0.472   0.159
200   N        -1.027  -1.048  -1.005  -1.025  -1.039  -0.978  -1.016  -1.027  -0.925
201   E         0.621   0.507   0.337   0.691   0.540   0.274   0.648   0.472   0.159
202   Y         0.621   0.589   0.342   0.779   0.733   0.358   0.648   0.599   0.168
203   E         1.328   1.347   1.421   1.304   1.328   1.456   1.424   1.454   1.569
204   Y         1.328   1.347   1.421   1.395   1.415   1.541   1.424   1.454   1.569
205   L         0.621   0.507   0.337   0.549   0.406   0.176   0.648   0.472   0.159
206   W         1.328   1.347   1.421   1.546   1.572   1.683   1.424   1.454   1.569
207   -         1.328   1.347   1.421   1.349   1.383   1.497   1.424   1.454   1.569
208   -        -0.651  -0.618  -0.521  -0.784  -0.711  -0.580  -0.847  -0.798  -0.663
209   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
210   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
211   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
212   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
213   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
214   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
215   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   A        -0.299  -0.237  -0.457  -0.199  -0.116  -0.504  -0.350  -0.267  -0.576
218   F        -1.922  -1.930  -1.760  -1.850  -1.850  -1.633  -1.460  -1.454  -1.243
219   Q        -1.067  -1.076  -1.014  -1.036  -1.055  -0.943  -1.039  -1.045  -0.933
220   K        -1.951  -1.936  -1.765  -1.729  -1.728  -1.498  -1.473  -1.454  -1.245
221   G        -1.150  -1.139  -1.034  -1.122  -1.118  -0.968  -1.127  -1.112  -0.953
222   Q        -0.947  -0.982  -0.995  -0.821  -0.860  -0.905  -0.905  -0.927  -0.911
223   P        -0.702  -0.699  -0.545  -0.820  -0.810  -0.588  -0.905  -0.900  -0.694
224   P         1.328   1.347   1.421   1.299   1.330   1.450   1.424   1.454   1.569
225   V        -0.499  -0.480  -0.487  -0.590  -0.586  -0.552  -0.683  -0.668  -0.626
226   S        -0.361  -0.446  -0.479  -0.342  -0.468  -0.510  -0.461  -0.585  -0.612
227   V        -0.702  -0.702  -0.544  -0.908  -0.896  -0.648  -0.905  -0.904  -0.693
228   S         0.087   0.085   0.182  -0.150  -0.163  -0.025  -0.240  -0.255  -0.125
229   A         1.328   1.347   1.421   1.360   1.380   1.508   1.424   1.454   1.569
230   P         0.273   0.351   0.292   0.264   0.378   0.290   0.093   0.219   0.079
231   K        -1.027  -1.097  -1.021  -0.978  -1.066  -0.939  -1.016  -1.069  -0.940
232   Y         1.328   1.347   1.421   1.395   1.415   1.541   1.424   1.454   1.569
233   V        -0.499  -0.402  -0.468  -0.566  -0.423  -0.498  -0.683  -0.559  -0.597
234   E        -0.052  -0.138  -0.398   0.102  -0.020  -0.404  -0.018  -0.138  -0.495
235   C        -1.800  -1.729  -1.752  -1.471  -1.384  -1.397  -1.349  -1.282  -1.236
236   L         1.328   1.347   1.421   1.146   1.173   1.306   1.424   1.454   1.569
237   M        -0.686  -0.773  -0.962  -0.328  -0.483  -0.821  -0.572  -0.678  -0.874
238   R        -1.597  -1.579  -1.439  -1.522  -1.485  -1.280  -1.349  -1.323  -1.131
239   W         1.328   1.347   1.421   1.546   1.572   1.683   1.424   1.454   1.569
240   C        -1.027  -1.033  -1.001  -0.876  -0.901  -0.847  -1.016  -1.014  -0.921
241   Q         1.328   1.347   1.421   1.307   1.342   1.458   1.424   1.454   1.569
242   D        -1.922  -1.946  -1.778  -1.719  -1.751  -1.520  -1.460  -1.463  -1.255
243   Q        -0.947  -1.015  -1.005  -0.918  -0.995  -1.006  -0.905  -0.964  -0.921
244   F        -0.361  -0.446  -0.479  -0.460  -0.620  -0.675  -0.461  -0.585  -0.612
245   D         1.328   1.347   1.421   1.390   1.426   1.536   1.424   1.454   1.569
246   D         0.028   0.055   0.182  -0.202  -0.148   0.042  -0.350  -0.312  -0.125
247   E        -0.361  -0.401  -0.444  -0.325  -0.368  -0.440  -0.461  -0.498  -0.559
248   S        -1.150  -1.183  -1.036  -1.212  -1.246  -1.025  -1.127  -1.147  -0.954
249   L        -1.150  -1.139  -1.031  -1.232  -1.244  -1.067  -1.127  -1.116  -0.951
250   F         0.621   0.589   0.342   0.634   0.592   0.199   0.648   0.599   0.168
251   P         1.328   1.347   1.421   1.299   1.330   1.450   1.424   1.454   1.569
252   S        -0.947  -0.925  -0.984  -0.896  -0.886  -0.937  -0.905  -0.892  -0.903
253   K        -0.361  -0.476  -0.478  -0.260  -0.433  -0.462  -0.461  -0.609  -0.610
254   V        -1.272  -1.156  -1.386  -1.052  -0.892  -1.298  -1.016  -0.894  -1.083
255   T        -0.052   0.088  -0.371   0.190   0.365  -0.304  -0.018   0.166  -0.458
256   G        -0.622  -0.610  -0.522  -0.661  -0.668  -0.536  -0.794  -0.785  -0.664
257   T        -0.686  -0.667  -0.940  -0.506  -0.493  -0.913  -0.572  -0.560  -0.850
258   F         1.328   1.347   1.421   1.267   1.293   1.420   1.424   1.454   1.569
259   P         1.328   1.347   1.421   1.299   1.330   1.450   1.424   1.454   1.569
260   E        -1.272  -1.079  -1.347  -0.939  -0.679  -1.082  -1.016  -0.812  -1.048
261   G        -1.922  -1.846  -1.764  -1.745  -1.644  -1.512  -1.460  -1.393  -1.245
262   F         1.328   1.347   1.421   1.267   1.293   1.420   1.424   1.454   1.569
263   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
264   Q        -1.800  -1.772  -1.760  -1.562  -1.520  -1.535  -1.349  -1.323  -1.242
265   R        -1.475  -1.497  -1.409  -1.342  -1.366  -1.245  -1.238  -1.246  -1.105
266   V        -1.027  -0.950  -0.994  -1.109  -1.012  -0.991  -1.016  -0.940  -0.913
267   I        -0.361  -0.363  -0.462  -0.303  -0.325  -0.470  -0.461  -0.477  -0.590
268   Q        -1.597  -1.545  -1.424  -1.484  -1.413  -1.245  -1.349  -1.298  -1.120
269   P        -0.702  -0.641  -0.519  -0.922  -0.821  -0.646  -0.905  -0.828  -0.661
270   I         1.328   1.347   1.421   1.355   1.384   1.503   1.424   1.454   1.569
271   L         0.028   0.056   0.181  -0.396  -0.350  -0.142  -0.350  -0.311  -0.126
272   R         0.087   0.103   0.192  -0.012   0.009   0.131  -0.240  -0.221  -0.107
273   R         1.328   1.347   1.421   1.398   1.434   1.543   1.424   1.454   1.569
274   L         0.621   0.589   0.342   0.563   0.529   0.221   0.648   0.599   0.168
275   F         0.621   0.589   0.342   0.669   0.631   0.291   0.648   0.599   0.168
276   R         1.328   1.347   1.421   1.398   1.434   1.543   1.424   1.454   1.569
277   V         0.087   0.097   0.198  -0.069  -0.063   0.087  -0.240  -0.233  -0.096
278   Y         1.328   1.347   1.421   1.395   1.415   1.541   1.424   1.454   1.569
279   A         1.328   1.347   1.421   1.360   1.380   1.508   1.424   1.454   1.569
280   H         1.328   1.347   1.421   1.440   1.469   1.583   1.424   1.454   1.569
281   I         1.328   1.347   1.421   1.355   1.384   1.503   1.424   1.454   1.569
282   Y         1.328   1.347   1.421   1.395   1.415   1.541   1.424   1.454   1.569
283   C         1.328   1.347   1.421   1.520   1.547   1.659   1.424   1.454   1.569
284   H         0.621   0.507   0.337   0.826   0.679   0.395   0.648   0.472   0.159
285   H         1.328   1.347   1.421   1.440   1.469   1.583   1.424   1.454   1.569
286   F         0.621   0.589   0.342   0.669   0.631   0.291   0.648   0.599   0.168
287   N        -1.027  -1.036  -1.016  -0.968  -0.960  -0.932  -1.016  -1.013  -0.935
288   E        -0.361  -0.432  -0.479  -0.357  -0.488  -0.552  -0.461  -0.574  -0.612
289   I        -0.052  -0.120  -0.387   0.180   0.092  -0.285  -0.018  -0.116  -0.480
290   L        -1.027  -1.097  -1.021  -1.170  -1.241  -1.102  -1.016  -1.069  -0.940
291   E         0.621   0.507   0.337   0.702   0.553   0.303   0.648   0.472   0.159
292   L         0.621   0.507   0.337   0.563   0.426   0.214   0.648   0.472   0.159
293   N        -0.499  -0.545  -0.493  -0.559  -0.602  -0.538  -0.683  -0.715  -0.630
294   L         1.328   1.347   1.421   1.146   1.173   1.306   1.424   1.454   1.569
295   Q         0.273   0.196   0.206   0.201   0.066   0.043   0.093  -0.052  -0.080
296   T        -0.702  -0.685  -0.544  -0.939  -0.916  -0.703  -0.905  -0.883  -0.692
297   V        -0.499  -0.545  -0.493  -0.478  -0.519  -0.446  -0.683  -0.715  -0.630
298   L         1.328   1.347   1.421   1.146   1.173   1.306   1.424   1.454   1.569
299   N         1.328   1.347   1.421   1.286   1.320   1.438   1.424   1.454   1.569
300   T         1.328   1.347   1.421   1.299   1.323   1.450   1.424   1.454   1.569
301   S         1.328   1.347   1.421   1.283   1.315   1.435   1.424   1.454   1.569
302   F         0.087   0.131   0.212  -0.252  -0.177  -0.066  -0.240  -0.170  -0.069
303   R         0.087   0.152   0.205  -0.012   0.096   0.156  -0.240  -0.132  -0.082
304   H         0.621   0.589   0.342   0.829   0.794   0.413   0.648   0.599   0.168
305   F        -0.499  -0.457  -0.476  -0.599  -0.547  -0.534  -0.683  -0.629  -0.609
306   C         0.087   0.152   0.205   0.018   0.115   0.194  -0.240  -0.132  -0.082
307   L         0.621   0.507   0.337   0.530   0.381   0.126   0.648   0.472   0.159
308   F         1.328   1.347   1.421   1.267   1.293   1.420   1.424   1.454   1.569
309   A        -1.475  -1.488  -1.402  -1.327  -1.329  -1.206  -1.238  -1.240  -1.101
310   Q        -1.922  -1.946  -1.778  -1.741  -1.748  -1.522  -1.460  -1.463  -1.255
311   E         1.328   1.347   1.421   1.304   1.328   1.456   1.424   1.454   1.569
312   F         0.621   0.589   0.342   0.676   0.640   0.308   0.648   0.599   0.168
313   E        -1.597  -1.528  -1.430  -1.511  -1.408  -1.264  -1.349  -1.285  -1.125
314   L        -0.052  -0.033  -0.385  -0.052  -0.027  -0.508  -0.018   0.007  -0.477
315   L        -1.475  -1.534  -1.433  -1.435  -1.498  -1.317  -1.238  -1.277  -1.125
316   R        -1.597  -1.522  -1.434  -1.486  -1.384  -1.255  -1.349  -1.281  -1.128
317   P        -2.247  -2.227  -2.059  -1.939  -1.922  -1.717  -1.571  -1.547  -1.339
318   A        -0.686  -0.541  -0.943  -0.416  -0.228  -0.840  -0.572  -0.401  -0.853
319   D         0.273   0.210   0.210   0.281   0.171   0.116   0.093  -0.026  -0.073
320   F         0.028   0.052   0.180  -0.212  -0.182   0.026  -0.350  -0.317  -0.129
321   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
322   G         0.273   0.210   0.210   0.316   0.197   0.161   0.093  -0.026  -0.073
323   P         1.328   1.347   1.421   1.299   1.330   1.450   1.424   1.454   1.569
324   L         0.621   0.507   0.337   0.563   0.426   0.214   0.648   0.472   0.159
325   L        -1.475  -1.534  -1.433  -1.492  -1.563  -1.383  -1.238  -1.277  -1.125
326   E         0.028   0.056   0.181  -0.189  -0.140   0.052  -0.350  -0.311  -0.126
327   L         1.328   1.347   1.421   1.146   1.173   1.306   1.424   1.454   1.569
328   V         0.621   0.622   0.347   0.744   0.746   0.356   0.648   0.648   0.177
329   M        -1.272  -1.156  -1.386  -0.934  -0.773  -1.135  -1.016  -0.894  -1.083
330   E        -1.150  -1.139  -1.034  -1.237  -1.232  -1.062  -1.127  -1.112  -0.953
331   L        -0.499  -0.445  -0.487  -0.580  -0.488  -0.563  -0.683  -0.609  -0.623
332   R        -0.947  -0.957  -0.999  -0.989  -0.995  -1.025  -0.905  -0.901  -0.916
333   D        -0.836  -0.847  -0.996  -0.581  -0.610  -0.854  -0.749  -0.768  -0.910
334   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
335   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
336   R        -0.836  -0.930  -0.980  -0.584  -0.744  -0.837  -0.749  -0.864  -0.893
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P40484
Output conservation file - output/P40484
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
