1     M         2.103   2.105   2.172   2.443   2.446   2.557   2.339   2.342   2.445
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     S        -0.615  -0.612  -0.570  -0.677  -0.668  -0.604  -0.700  -0.696  -0.631
4     Y        -0.615  -0.612  -0.570  -0.847  -0.840  -0.776  -0.700  -0.696  -0.631
5     K         0.528   0.533   0.532   0.540   0.545   0.545   0.313   0.321   0.303
6     K        -0.469  -0.468  -0.479  -0.245  -0.238  -0.260  -0.510  -0.508  -0.513
7     F        -0.469  -0.468  -0.479  -0.812  -0.827  -0.842  -0.510  -0.508  -0.513
8     V        -0.469  -0.457  -0.481  -0.606  -0.599  -0.614  -0.510  -0.494  -0.515
9     Y        -1.327  -1.324  -1.288  -1.237  -1.235  -1.171  -1.080  -1.077  -1.015
10    F        -1.327  -1.324  -1.288  -1.529  -1.545  -1.466  -1.080  -1.077  -1.015
11    I        -0.469  -0.467  -0.482  -0.529  -0.540  -0.575  -0.510  -0.507  -0.516
12    N        -1.327  -1.324  -1.288  -1.217  -1.211  -1.150  -1.080  -1.077  -1.015
13    L        -0.469  -0.443  -0.462  -0.606  -0.578  -0.588  -0.510  -0.475  -0.490
14    F         0.712   0.741   0.655   0.527   0.568   0.419   0.629   0.678   0.521
15    F         0.712   0.741   0.655   0.527   0.568   0.419   0.629   0.678   0.521
16    L         0.388   0.390   0.442   0.112   0.100   0.197   0.060   0.062   0.138
17    L        -0.469  -0.468  -0.479  -0.731  -0.732  -0.754  -0.510  -0.508  -0.513
18    G         0.712   0.687   0.625   0.713   0.670   0.583   0.629   0.588   0.469
19    A         0.388   0.390   0.442  -0.042  -0.038   0.042   0.060   0.062   0.139
20    T        -0.469  -0.477  -0.492  -0.634  -0.648  -0.684  -0.510  -0.521  -0.530
21    L         0.712   0.687   0.625   0.579   0.527   0.452   0.629   0.588   0.469
22    L         2.103   2.105   2.172   1.925   1.914   2.032   2.339   2.342   2.445
23    T        -0.469  -0.457  -0.481  -0.745  -0.736  -0.770  -0.510  -0.494  -0.515
24    F        -0.469  -0.477  -0.492  -0.438  -0.453  -0.448  -0.510  -0.521  -0.530
25    F         0.712   0.725   0.646   0.527   0.540   0.403   0.629   0.650   0.506
26    L        -0.469  -0.468  -0.479  -0.601  -0.590  -0.634  -0.510  -0.508  -0.513
27    I         0.712   0.741   0.655   0.788   0.829   0.678   0.629   0.678   0.521
28    L         0.712   0.725   0.646   0.579   0.581   0.485   0.629   0.650   0.506
29    A        -0.469  -0.477  -0.492  -0.631  -0.648  -0.663  -0.510  -0.521  -0.530
30    G         2.103   2.105   2.172   2.063   2.063   2.172   2.339   2.342   2.445
31    G        -0.469  -0.490  -0.487  -0.615  -0.652  -0.636  -0.510  -0.538  -0.523
32    R        -0.469  -0.477  -0.492  -0.519  -0.532  -0.569  -0.510  -0.521  -0.530
33    T        -0.469  -0.467  -0.482  -0.422  -0.412  -0.429  -0.510  -0.507  -0.516
34    T         0.388   0.391   0.444   0.038   0.048   0.126   0.060   0.064   0.141
35    G        -0.469  -0.457  -0.481  -0.688  -0.667  -0.719  -0.510  -0.494  -0.515
36    V         0.388   0.390   0.442   0.309   0.325   0.396   0.060   0.062   0.138
37    L         2.103   2.105   2.172   1.925   1.914   2.032   2.339   2.342   2.445
38    K        -1.327  -1.324  -1.288  -1.153  -1.150  -1.086  -1.080  -1.077  -1.015
39    N        -0.469  -0.477  -0.492  -0.180  -0.187  -0.199  -0.510  -0.521  -0.530
40    F         0.712   0.687   0.625   0.571   0.530   0.422   0.629   0.588   0.469
41    Y         2.103   2.105   2.172   2.337   2.350   2.449   2.339   2.342   2.445
42    W         0.712   0.687   0.625   0.951   0.905   0.787   0.629   0.588   0.469
43    F        -0.469  -0.468  -0.479  -0.780  -0.794  -0.806  -0.510  -0.508  -0.513
44    Q        -0.469  -0.490  -0.487  -0.141  -0.170  -0.164  -0.510  -0.538  -0.523
45    A         0.712   0.725   0.646   0.540   0.560   0.428   0.629   0.650   0.506
46    S        -0.469  -0.457  -0.481  -0.213  -0.180  -0.235  -0.510  -0.494  -0.515
47    T         2.103   2.105   2.172   2.057   2.066   2.165   2.339   2.342   2.445
48    S         2.103   2.105   2.172   2.020   2.026   2.128   2.339   2.342   2.445
49    G         0.712   0.741   0.655   0.715   0.754   0.633   0.629   0.678   0.521
50    F        -0.469  -0.468  -0.479  -0.529  -0.539  -0.570  -0.510  -0.508  -0.513
51    N        -1.327  -1.324  -1.288  -1.217  -1.214  -1.150  -1.080  -1.077  -1.015
52    S         0.712   0.703   0.639   0.639   0.620   0.509   0.629   0.614   0.493
53    A         0.712   0.725   0.646   0.565   0.588   0.460   0.629   0.650   0.506
54    P        -0.469  -0.467  -0.482  -0.183  -0.183  -0.195  -0.510  -0.507  -0.516
55    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    S        -0.469  -0.468  -0.479  -0.260  -0.245  -0.285  -0.510  -0.508  -0.513
57    V        -0.469  -0.443  -0.462  -0.473  -0.415  -0.462  -0.510  -0.475  -0.490
58    T         0.712   0.687   0.625   0.632   0.597   0.478   0.629   0.588   0.469
59    R         0.712   0.687   0.625   0.863   0.833   0.749   0.629   0.588   0.469
60    W         2.103   2.105   2.172   2.396   2.398   2.509   2.339   2.342   2.445
61    Y         0.712   0.703   0.639   0.737   0.732   0.637   0.629   0.614   0.493
62    N        -1.327  -1.324  -1.288  -1.224  -1.207  -1.157  -1.080  -1.077  -1.015
63    Y         0.712   0.687   0.625   0.894   0.859   0.730   0.629   0.588   0.469
64    N        -0.469  -0.477  -0.492  -0.296  -0.305  -0.330  -0.510  -0.521  -0.530
65    W        -1.327  -1.324  -1.288  -1.046  -1.037  -0.977  -1.080  -1.077  -1.015
66    C         2.103   2.105   2.172   2.420   2.424   2.533   2.339   2.342   2.445
67    G         2.103   2.105   2.172   2.063   2.063   2.172   2.339   2.342   2.445
68    W        -0.469  -0.490  -0.487  -0.449  -0.481  -0.477  -0.510  -0.538  -0.523
69    E        -1.327  -1.324  -1.288  -1.014  -0.995  -0.945  -1.080  -1.077  -1.015
70    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
71    R        -0.615  -0.613  -0.570  -0.321  -0.321  -0.243  -0.700  -0.698  -0.631
72    G         0.528   0.540   0.525   0.505   0.521   0.484   0.313   0.333   0.290
73    I         0.528   0.540   0.525   0.602   0.618   0.587   0.313   0.333   0.290
74    A         0.712   0.703   0.639   0.802   0.788   0.663   0.629   0.614   0.493
75    V        -1.327  -1.324  -1.288  -1.602  -1.602  -1.540  -1.080  -1.077  -1.015
76    N        -1.327  -1.324  -1.288  -0.804  -0.793  -0.732  -1.080  -1.077  -1.015
77    C         2.103   2.105   2.172   2.420   2.424   2.533   2.339   2.342   2.445
78    S         0.388   0.390   0.442   0.043   0.044   0.127   0.060   0.062   0.139
79    S        -0.469  -0.490  -0.487  -0.311  -0.343  -0.344  -0.510  -0.538  -0.523
80    K        -1.327  -1.324  -1.288  -1.289  -1.289  -1.223  -1.080  -1.077  -1.015
81    M        -0.469  -0.490  -0.487  -0.083  -0.115  -0.108  -0.510  -0.538  -0.523
82    A         0.712   0.687   0.625   0.626   0.591   0.506   0.629   0.588   0.469
83    A         0.712   0.741   0.655   0.649   0.693   0.579   0.629   0.678   0.521
84    Q        -0.469  -0.490  -0.487  -0.562  -0.605  -0.582  -0.510  -0.538  -0.523
85    P         2.103   2.105   2.172   2.313   2.320   2.425   2.339   2.342   2.445
86    F        -0.469  -0.477  -0.492  -0.606  -0.631  -0.639  -0.510  -0.521  -0.530
87    S        -0.469  -0.467  -0.482  -0.494  -0.491  -0.504  -0.510  -0.507  -0.516
88    P         0.712   0.687   0.625   0.995   0.966   0.872   0.629   0.588   0.469
89    R        -1.327  -1.324  -1.288  -1.237  -1.229  -1.171  -1.080  -1.077  -1.015
90    D        -0.469  -0.467  -0.482  -0.146  -0.127  -0.163  -0.510  -0.507  -0.516
91    N         0.712   0.687   0.625   0.938   0.909   0.816   0.629   0.588   0.469
92    F         2.103   2.105   2.172   1.965   1.963   2.072   2.339   2.342   2.445
93    G         0.712   0.687   0.625   0.639   0.594   0.484   0.629   0.588   0.469
94    S        -1.327  -1.324  -1.288  -1.306  -1.295  -1.241  -1.080  -1.077  -1.015
95    S        -1.327  -1.324  -1.288  -1.049  -1.045  -0.980  -1.080  -1.077  -1.015
96    P        -1.327  -1.324  -1.288  -1.210  -1.210  -1.143  -1.080  -1.077  -1.015
97    L         0.712   0.703   0.639   0.608   0.583   0.469   0.629   0.614   0.493
98    M        -0.469  -0.490  -0.487  -0.319  -0.362  -0.347  -0.510  -0.538  -0.523
99    P         2.103   2.105   2.172   2.313   2.320   2.425   2.339   2.342   2.445
100   S        -0.469  -0.490  -0.487  -0.339  -0.380  -0.398  -0.510  -0.538  -0.523
101   T        -1.327  -1.324  -1.288  -1.163  -1.166  -1.096  -1.080  -1.077  -1.015
102   F         0.712   0.687   0.625   0.527   0.478   0.364   0.629   0.588   0.469
103   L        -0.469  -0.490  -0.487  -0.497  -0.548  -0.549  -0.510  -0.538  -0.523
104   N        -0.469  -0.468  -0.479  -0.375  -0.371  -0.374  -0.510  -0.508  -0.513
105   N        -1.327  -1.324  -1.288  -1.037  -1.018  -0.967  -1.080  -1.077  -1.015
106   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
107   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
108   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
109   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
110   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
111   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
112   R         0.528   0.509   0.530   0.386   0.355   0.373   0.313   0.279   0.299
113   N        -0.469  -0.468  -0.479  -0.066  -0.060  -0.077  -0.510  -0.508  -0.513
114   A        -1.327  -1.324  -1.288  -1.220  -1.210  -1.153  -1.080  -1.077  -1.015
115   Y        -0.469  -0.467  -0.482  -0.250  -0.250  -0.274  -0.510  -0.507  -0.516
116   Y         0.712   0.687   0.625   1.023   0.995   0.901   0.629   0.588   0.469
117   Y         2.103   2.105   2.172   2.337   2.350   2.449   2.339   2.342   2.445
118   L         0.712   0.687   0.625   0.647   0.598   0.541   0.629   0.588   0.469
119   S        -0.469  -0.467  -0.482  -0.489  -0.478  -0.498  -0.510  -0.507  -0.516
120   R         2.103   2.105   2.172   2.156   2.163   2.266   2.339   2.342   2.445
121   V         0.388   0.390   0.442   0.066   0.078   0.149   0.060   0.062   0.138
122   G         0.712   0.741   0.655   0.616   0.659   0.509   0.629   0.678   0.521
123   W         0.712   0.741   0.655   0.951   0.997   0.844   0.629   0.678   0.521
124   A        -0.469  -0.467  -0.482  -0.554  -0.547  -0.561  -0.510  -0.507  -0.516
125   M         0.712   0.703   0.639   0.701   0.686   0.613   0.629   0.614   0.493
126   L        -1.327  -1.324  -1.288  -1.299  -1.316  -1.234  -1.080  -1.077  -1.015
127   L         2.103   2.105   2.172   1.925   1.914   2.032   2.339   2.342   2.445
128   I        -0.469  -0.477  -0.492  -0.465  -0.488  -0.522  -0.510  -0.521  -0.530
129   G        -0.469  -0.467  -0.482  -0.668  -0.671  -0.705  -0.510  -0.507  -0.516
130   L         2.103   2.105   2.172   1.925   1.914   2.032   2.339   2.342   2.445
131   F         2.103   2.105   2.172   1.982   1.983   2.089   2.339   2.342   2.445
132   F         2.103   2.105   2.172   1.982   1.983   2.089   2.339   2.342   2.445
133   L        -1.327  -1.324  -1.288  -1.345  -1.343  -1.280  -1.080  -1.077  -1.015
134   L        -0.469  -0.490  -0.487  -0.601  -0.632  -0.649  -0.510  -0.538  -0.523
135   I        -0.469  -0.477  -0.492  -0.497  -0.525  -0.559  -0.510  -0.521  -0.530
136   T         0.388   0.390   0.442  -0.013  -0.009   0.068   0.060   0.062   0.139
137   L        -0.469  -0.477  -0.492  -0.581  -0.615  -0.602  -0.510  -0.521  -0.530
138   V         0.388   0.390   0.442   0.066   0.078   0.149   0.060   0.062   0.138
139   S        -0.469  -0.443  -0.462  -0.657  -0.605  -0.651  -0.510  -0.475  -0.490
140   V        -1.327  -1.324  -1.288  -1.495  -1.482  -1.431  -1.080  -1.077  -1.015
141   I        -1.327  -1.324  -1.288  -1.313  -1.322  -1.248  -1.080  -1.077  -1.015
142   A        -0.469  -0.457  -0.481  -0.812  -0.809  -0.845  -0.510  -0.494  -0.515
143   S        -0.469  -0.477  -0.492  -0.601  -0.617  -0.639  -0.510  -0.521  -0.530
144   L        -0.469  -0.477  -0.492  -0.592  -0.614  -0.614  -0.510  -0.521  -0.530
145   I        -0.469  -0.490  -0.487  -0.265  -0.318  -0.312  -0.510  -0.538  -0.523
146   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
147   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
148   N        -1.327  -1.324  -1.288  -1.200  -1.194  -1.133  -1.080  -1.077  -1.015
149   R         0.712   0.725   0.646   0.717   0.740   0.596   0.629   0.650   0.506
150   R        -0.469  -0.457  -0.481  -0.557  -0.524  -0.587  -0.510  -0.494  -0.515
151   T        -0.469  -0.468  -0.479  -0.651  -0.652  -0.681  -0.510  -0.508  -0.513
152   A        -0.469  -0.443  -0.462  -0.719  -0.678  -0.712  -0.510  -0.475  -0.490
153   A         0.712   0.725   0.646   0.604   0.620   0.509   0.629   0.650   0.506
154   L         0.388   0.390   0.442   0.024   0.030   0.110   0.060   0.062   0.139
155   A        -0.469  -0.477  -0.492  -0.719  -0.737  -0.763  -0.510  -0.521  -0.530
156   T        -1.327  -1.324  -1.288  -1.363  -1.366  -1.298  -1.080  -1.077  -1.015
157   A        -1.327  -1.324  -1.288  -1.310  -1.298  -1.244  -1.080  -1.077  -1.015
158   M        -1.327  -1.324  -1.288  -1.183  -1.174  -1.116  -1.080  -1.077  -1.015
159   S        -0.469  -0.457  -0.481  -0.631  -0.616  -0.646  -0.510  -0.494  -0.515
160   W        -1.327  -1.324  -1.288  -1.381  -1.376  -1.316  -1.080  -1.077  -1.015
161   I        -0.469  -0.477  -0.492  -0.465  -0.488  -0.522  -0.510  -0.521  -0.530
162   T        -0.469  -0.490  -0.487  -0.691  -0.727  -0.733  -0.510  -0.538  -0.523
163   L         0.712   0.741   0.655   0.540   0.575   0.450   0.629   0.678   0.521
164   F        -0.469  -0.477  -0.492  -0.702  -0.717  -0.749  -0.510  -0.521  -0.530
165   F         0.712   0.687   0.625   0.701   0.664   0.594   0.629   0.588   0.469
166   I        -1.327  -1.324  -1.288  -1.193  -1.202  -1.126  -1.080  -1.077  -1.015
167   T        -0.469  -0.477  -0.492  -0.540  -0.554  -0.577  -0.510  -0.521  -0.530
168   L        -0.469  -0.468  -0.479  -0.497  -0.505  -0.533  -0.510  -0.508  -0.513
169   S         0.712   0.703   0.639   0.527   0.512   0.399   0.629   0.614   0.493
170   A         0.712   0.687   0.625   0.565   0.531   0.425   0.629   0.588   0.469
171   C         0.388   0.390   0.442   0.309   0.313   0.395   0.060   0.062   0.138
172   L         0.712   0.725   0.646   0.639   0.641   0.560   0.629   0.650   0.506
173   Y        -1.327  -1.324  -1.288  -0.999  -0.985  -0.929  -1.080  -1.077  -1.015
174   T         2.103   2.105   2.172   2.057   2.066   2.165   2.339   2.342   2.445
175   G         0.712   0.703   0.639   0.542   0.525   0.418   0.629   0.614   0.493
176   C        -0.469  -0.477  -0.492  -0.334  -0.350  -0.401  -0.510  -0.521  -0.530
177   Y        -0.469  -0.477  -0.492  -0.233  -0.248  -0.272  -0.510  -0.521  -0.530
178   A        -1.327  -1.324  -1.288  -1.498  -1.481  -1.435  -1.080  -1.077  -1.015
179   K         0.712   0.741   0.655   0.989   1.035   0.918   0.629   0.678   0.521
180   A        -0.469  -0.477  -0.492  -0.524  -0.535  -0.541  -0.510  -0.521  -0.530
181   V        -0.469  -0.457  -0.481  -0.388  -0.362  -0.402  -0.510  -0.494  -0.515
182   K        -1.327  -1.324  -1.288  -1.153  -1.145  -1.086  -1.080  -1.077  -1.015
183   A        -1.327  -1.324  -1.288  -0.999  -0.995  -0.929  -1.080  -1.077  -1.015
184   F         0.712   0.725   0.646   0.685   0.699   0.603   0.629   0.650   0.506
185   H        -0.469  -0.443  -0.462  -0.066  -0.020  -0.048  -0.510  -0.475  -0.490
186   H        -0.469  -0.457  -0.481  -0.198  -0.179  -0.190  -0.510  -0.494  -0.515
187   E        -0.615  -0.612  -0.570  -0.525  -0.499  -0.449  -0.700  -0.696  -0.631
188   N         0.528   0.523   0.531   0.383   0.375   0.385   0.313   0.303   0.301
189   R         0.528   0.561   0.548   0.383   0.446   0.404   0.313   0.369   0.332
190   D        -0.615  -0.612  -0.570  -0.329  -0.303  -0.251  -0.700  -0.696  -0.631
191   A         0.712   0.725   0.646   0.540   0.560   0.428   0.629   0.650   0.506
192   R        -0.469  -0.468  -0.479  -0.205  -0.197  -0.232  -0.510  -0.508  -0.513
193   L         2.103   2.105   2.172   1.925   1.914   2.032   2.339   2.342   2.445
194   G         2.103   2.105   2.172   2.063   2.063   2.172   2.339   2.342   2.445
195   P        -1.327  -1.324  -1.288  -1.310  -1.298  -1.244  -1.080  -1.077  -1.015
196   K         0.712   0.687   0.625   0.959   0.928   0.832   0.629   0.588   0.469
197   N        -0.469  -0.457  -0.481  -0.441  -0.430  -0.434  -0.510  -0.494  -0.515
198   F         2.103   2.105   2.172   1.982   1.983   2.089   2.339   2.342   2.445
199   G         0.712   0.741   0.655   0.616   0.659   0.509   0.629   0.678   0.521
200   L        -0.469  -0.468  -0.479  -0.648  -0.661  -0.667  -0.510  -0.508  -0.513
201   I        -0.469  -0.477  -0.492  -0.543  -0.572  -0.612  -0.510  -0.521  -0.530
202   W         2.103   2.105   2.172   2.396   2.398   2.509   2.339   2.342   2.445
203   T         0.712   0.687   0.625   0.647   0.610   0.497   0.629   0.588   0.469
204   T         0.388   0.390   0.442  -0.013  -0.009   0.068   0.060   0.062   0.139
205   V        -0.469  -0.467  -0.482  -0.263  -0.245  -0.261  -0.510  -0.507  -0.516
206   F         0.388   0.390   0.442  -0.070  -0.072   0.011   0.060   0.062   0.139
207   L        -1.327  -1.324  -1.288  -1.268  -1.289  -1.202  -1.080  -1.077  -1.015
208   L         2.103   2.105   2.172   1.925   1.914   2.032   2.339   2.342   2.445
209   I        -0.469  -0.490  -0.487  -0.688  -0.741  -0.715  -0.510  -0.538  -0.523
210   V        -0.469  -0.457  -0.481  -0.465  -0.444  -0.500  -0.510  -0.494  -0.515
211   N        -0.469  -0.457  -0.481  -0.554  -0.529  -0.569  -0.510  -0.494  -0.515
212   A        -1.327  -1.324  -1.288  -1.650  -1.654  -1.588  -1.080  -1.077  -1.015
213   I        -0.469  -0.457  -0.481  -0.492  -0.458  -0.514  -0.510  -0.494  -0.515
214   C        -1.327  -1.324  -1.288  -1.381  -1.386  -1.316  -1.080  -1.077  -1.015
215   C        -0.469  -0.468  -0.479  -0.568  -0.572  -0.577  -0.510  -0.508  -0.513
216   T        -1.327  -1.324  -1.288  -1.487  -1.489  -1.424  -1.080  -1.077  -1.015
217   I        -1.327  -1.324  -1.288  -1.421  -1.423  -1.356  -1.080  -1.077  -1.015
218   M        -0.469  -0.468  -0.479  -0.584  -0.588  -0.591  -0.510  -0.508  -0.513
219   V        -1.327  -1.324  -1.288  -0.996  -0.983  -0.926  -1.080  -1.077  -1.015
220   A        -0.469  -0.490  -0.487  -0.388  -0.444  -0.452  -0.510  -0.538  -0.523
221   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
222   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
223   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
224   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   T        -0.469  -0.467  -0.482  -0.521  -0.508  -0.539  -0.510  -0.507  -0.516
227   H         0.712   0.703   0.639   0.865   0.855   0.772   0.629   0.614   0.493
228   K        -0.469  -0.477  -0.492  -0.228  -0.229  -0.258  -0.510  -0.521  -0.530
229   R        -0.469  -0.467  -0.482  -0.260  -0.254  -0.261  -0.510  -0.507  -0.516
230   N         2.103   2.105   2.172   2.240   2.249   2.351   2.339   2.342   2.445
231   E        -0.615  -0.612  -0.570  -0.405  -0.385  -0.328  -0.700  -0.696  -0.631
232   Y         0.528   0.561   0.548   0.564   0.637   0.583   0.313   0.369   0.332
233   I         0.528   0.523   0.531   0.442   0.455   0.444   0.313   0.303   0.301
234   Y        -0.615  -0.612  -0.570  -0.606  -0.584  -0.531  -0.700  -0.696  -0.631
235   D        -0.615  -0.612  -0.570  -0.620  -0.580  -0.545  -0.700  -0.696  -0.631
236   R         0.528   0.561   0.548   0.394   0.458   0.416   0.313   0.369   0.332
237   S        -0.615  -0.612  -0.570  -0.808  -0.822  -0.736  -0.700  -0.696  -0.631
238   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
239   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
240   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
241   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
242   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
243   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
244   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
245   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
246   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
247   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
248   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
249   P         0.528   0.523   0.531   0.464   0.458   0.469   0.313   0.303   0.301
250   T         0.528   0.523   0.531   0.589   0.590   0.576   0.313   0.303   0.301
251   P         0.528   0.523   0.531   0.360   0.340   0.368   0.313   0.303   0.301
252   V        -0.615  -0.612  -0.570  -0.688  -0.672  -0.614  -0.700  -0.696  -0.631
253   P         0.528   0.523   0.531   0.739   0.739   0.739   0.313   0.303   0.301
254   T        -0.615  -0.612  -0.570  -0.880  -0.879  -0.809  -0.700  -0.696  -0.631
255   N        -0.615  -0.612  -0.570  -0.520  -0.507  -0.445  -0.700  -0.696  -0.631
256   G         0.528   0.509   0.530   0.445   0.427   0.455   0.313   0.279   0.299
257   G        -0.615  -0.612  -0.570  -0.460  -0.455  -0.384  -0.700  -0.696  -0.631
258   I         0.528   0.509   0.530   0.525   0.497   0.510   0.313   0.279   0.299
259   P         0.528   0.509   0.530   0.568   0.547   0.552   0.313   0.279   0.299
260   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
261   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
262   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
263   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
264   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
265   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
266   S        -0.615  -0.612  -0.570  -0.954  -0.964  -0.884  -0.700  -0.696  -0.631
267   S        -0.469  -0.477  -0.492  -0.412  -0.412  -0.425  -0.510  -0.521  -0.530
268   V        -1.327  -1.324  -1.288  -1.210  -1.204  -1.143  -1.080  -1.077  -1.015
269   P         0.712   0.741   0.655   0.966   1.013   0.884   0.629   0.678   0.521
270   V         2.103   2.105   2.172   2.131   2.152   2.241   2.339   2.342   2.445
271   T         0.712   0.741   0.655   0.747   0.795   0.674   0.629   0.678   0.521
272   E        -0.469  -0.457  -0.481  -0.481  -0.460  -0.493  -0.510  -0.494  -0.515
273   V        -0.469  -0.457  -0.481  -0.235  -0.206  -0.252  -0.510  -0.494  -0.515
274   Q        -0.469  -0.468  -0.479  -0.470  -0.463  -0.473  -0.510  -0.508  -0.513
275   Q         0.712   0.703   0.639   1.062   1.057   0.965   0.629   0.614   0.493
276   S        -1.327  -1.324  -1.288  -1.282  -1.282  -1.216  -1.080  -1.077  -1.015
277   Q        -0.469  -0.477  -0.492  -0.114  -0.124  -0.152  -0.510  -0.521  -0.530
278   S        -1.327  -1.324  -1.288  -1.143  -1.138  -1.076  -1.080  -1.077  -1.015
279   H        -0.469  -0.468  -0.479  -0.409  -0.409  -0.423  -0.510  -0.508  -0.513
280   Q        -0.615  -0.613  -0.570  -0.713  -0.703  -0.640  -0.700  -0.698  -0.631
281   N         2.103   2.105   2.172   2.222   2.224   2.333   2.339   2.342   2.445
282   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
283   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
284   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
285   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
286   K        -0.469  -0.477  -0.492  -0.360  -0.376  -0.409  -0.510  -0.521  -0.530
287   K        -0.469  -0.490  -0.487  -0.537  -0.564  -0.554  -0.510  -0.538  -0.523
288   L         0.712   0.703   0.639   0.527   0.504   0.390   0.629   0.614   0.493
289   R         0.712   0.687   0.625   0.804   0.771   0.672   0.629   0.588   0.469
290   T        -0.469  -0.477  -0.492  -0.425  -0.425  -0.446  -0.510  -0.521  -0.530
291   K        -0.469  -0.467  -0.482  -0.417  -0.413  -0.455  -0.510  -0.507  -0.516
292   K         0.712   0.703   0.639   0.816   0.807   0.710   0.629   0.614   0.493
293   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
294   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
295   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
296   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
297   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
298   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
299   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
300   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
301   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
302   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
303   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
304   R         0.528   0.556   0.548   0.540   0.582   0.571   0.313   0.361   0.332
305   V        -0.469  -0.468  -0.479  -0.657  -0.645  -0.681  -0.510  -0.508  -0.513
306   Q        -0.469  -0.490  -0.487  -0.166  -0.194  -0.180  -0.510  -0.538  -0.523
307   E         0.712   0.703   0.639   0.711   0.703   0.615   0.629   0.614   0.493
308   E        -0.469  -0.467  -0.482  -0.334  -0.327  -0.372  -0.510  -0.507  -0.516
309   R        -1.327  -1.324  -1.288  -1.085  -1.071  -1.016  -1.080  -1.077  -1.015
310   V         0.712   0.687   0.625   0.705   0.681   0.549   0.629   0.588   0.469
311   Y        -0.615  -0.612  -0.570  -0.730  -0.725  -0.656  -0.700  -0.696  -0.631
312   T        -0.615  -0.612  -0.570  -0.672  -0.654  -0.598  -0.700  -0.696  -0.631
313   E        -0.615  -0.612  -0.570  -0.693  -0.687  -0.619  -0.700  -0.696  -0.631
314   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
315   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
316   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
317   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
318   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
319   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
320   S        -0.615  -0.612  -0.570  -0.809  -0.792  -0.737  -0.700  -0.696  -0.631
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P40169
Output conservation file - output/P40169
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
