1     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    M        -0.014  -0.075  -0.321   0.372   0.273  -0.113  -0.008  -0.099  -0.446
24    N        -1.082  -1.031  -0.937  -1.139  -1.005  -0.916  -1.122  -1.040  -0.909
25    S        -1.834  -1.848  -1.673  -1.779  -1.792  -1.537  -1.456  -1.442  -1.229
26    V        -1.102  -1.104  -0.975  -1.163  -1.182  -1.023  -1.127  -1.121  -0.947
27    K         0.506   0.550   0.356   0.489   0.558   0.287   0.450   0.516   0.146
28    R        -0.517  -0.436  -0.430  -0.586  -0.451  -0.445  -0.738  -0.618  -0.602
29    V        -0.939  -0.788  -0.920  -0.882  -0.651  -0.887  -0.937  -0.749  -0.887
30    K         1.328   1.350   1.440   1.225   1.267   1.405   1.440   1.470   1.617
31    L        -0.255  -0.390  -0.415  -0.317  -0.517  -0.580  -0.342  -0.545  -0.579
32    N        -0.939  -0.788  -0.920  -0.951  -0.738  -0.948  -0.937  -0.749  -0.887
33    S        -1.102  -1.076  -0.965  -1.300  -1.259  -1.096  -1.127  -1.093  -0.936
34    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    S        -1.002  -1.026  -0.945  -0.944  -1.027  -0.937  -1.034  -1.054  -0.918
37    K        -1.002  -0.937  -0.922  -1.199  -1.089  -1.069  -1.034  -0.947  -0.892
38    Q        -0.646  -0.641  -0.481  -0.749  -0.743  -0.507  -0.899  -0.884  -0.670
39    I         1.328   1.350   1.440   1.326   1.365   1.500   1.440   1.470   1.617
40    C        -0.314  -0.424  -0.419  -0.099  -0.320  -0.348  -0.454  -0.614  -0.590
41    T         1.328   1.350   1.440   1.418   1.443   1.587   1.440   1.470   1.617
42    H         1.328   1.350   1.440   1.501   1.527   1.666   1.440   1.470   1.617
43    S         0.641   0.523   0.396   0.627   0.506   0.308   0.660   0.472   0.221
44    G         1.328   1.350   1.440   1.281   1.304   1.458   1.440   1.470   1.617
45    S        -1.201  -1.306  -1.312  -1.015  -1.149  -1.139  -1.011  -1.114  -1.072
46    F         1.328   1.350   1.440   1.332   1.366   1.506   1.440   1.470   1.617
47    H         1.328   1.350   1.440   1.501   1.527   1.666   1.440   1.470   1.617
48    A         1.328   1.350   1.440   1.271   1.292   1.448   1.440   1.470   1.617
49    D         1.328   1.350   1.440   1.258   1.285   1.435   1.440   1.470   1.617
50    E         1.328   1.350   1.440   1.260   1.289   1.437   1.440   1.470   1.617
51    S         0.121   0.111   0.228  -0.208  -0.229  -0.054  -0.231  -0.262  -0.097
52    L         1.328   1.350   1.440   1.188   1.223   1.370   1.440   1.470   1.617
53    A         1.328   1.350   1.440   1.271   1.292   1.448   1.440   1.470   1.617
54    V         1.328   1.350   1.440   1.306   1.339   1.482   1.440   1.470   1.617
55    Y        -0.314  -0.418  -0.409  -0.149  -0.292  -0.309  -0.454  -0.582  -0.577
56    M         0.641   0.760   0.424   0.938   1.087   0.590   0.660   0.833   0.273
57    L         0.641   0.711   0.418   0.593   0.687   0.291   0.660   0.763   0.261
58    R         0.121   0.161   0.245  -0.053   0.012   0.110  -0.231  -0.166  -0.065
59    L        -0.314  -0.424  -0.419  -0.362  -0.514  -0.470  -0.454  -0.614  -0.590
60    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
61    L         0.641   0.523   0.396   0.590   0.442   0.248   0.660   0.472   0.221
62    P         0.641   0.603   0.412   0.838   0.788   0.489   0.660   0.600   0.250
63    E        -0.885  -0.874  -0.901  -0.894  -0.876  -0.888  -0.899  -0.878  -0.872
64    F        -0.449  -0.397  -0.411  -0.429  -0.362  -0.322  -0.677  -0.610  -0.585
65    K        -0.885  -0.909  -0.914  -0.914  -0.929  -0.925  -0.899  -0.915  -0.885
66    D        -0.885  -0.816  -0.913  -0.859  -0.821  -0.869  -0.899  -0.844  -0.885
67    A         0.302   0.376   0.294   0.157   0.270   0.093   0.103   0.225   0.031
68    K        -1.398  -1.427  -1.338  -1.315  -1.348  -1.216  -1.234  -1.246  -1.099
69    L        -0.314  -0.235  -0.381  -0.442  -0.337  -0.541  -0.454  -0.358  -0.539
70    V         0.641   0.711   0.418   0.711   0.804   0.399   0.660   0.763   0.261
71    R         1.328   1.350   1.440   1.405   1.428   1.575   1.440   1.470   1.617
72    S         0.641   0.523   0.396   0.627   0.502   0.307   0.660   0.472   0.221
73    R         1.328   1.350   1.440   1.405   1.428   1.575   1.440   1.470   1.617
74    N         0.121   0.097   0.227  -0.027  -0.102   0.086  -0.231  -0.288  -0.100
75    P         0.641   0.581   0.410   0.879   0.810   0.585   0.660   0.566   0.246
76    K        -1.201  -1.217  -1.291  -1.073  -1.105  -1.243  -1.011  -1.024  -1.053
77    D        -0.631  -0.826  -0.894  -0.511  -0.805  -0.926  -0.565  -0.795  -0.858
78    W         0.121   0.097   0.227   0.048  -0.054   0.129  -0.231  -0.288  -0.100
79    E         0.302   0.251   0.274   0.161   0.061   0.068   0.103   0.002  -0.007
80    A        -0.963  -1.043  -0.935  -1.109  -1.192  -1.032  -1.011  -1.065  -0.908
81    S         0.121   0.097   0.227  -0.042  -0.039   0.156  -0.231  -0.288  -0.100
82    D         1.328   1.350   1.440   1.258   1.285   1.435   1.440   1.470   1.617
83    I         0.641   0.711   0.418   0.728   0.826   0.410   0.660   0.763   0.261
84    L        -0.014   0.033  -0.295   0.102   0.167  -0.334  -0.008   0.052  -0.408
85    V         0.641   0.711   0.418   0.711   0.804   0.399   0.660   0.763   0.261
86    D         1.328   1.350   1.440   1.258   1.285   1.435   1.440   1.470   1.617
87    V         1.328   1.350   1.440   1.306   1.339   1.482   1.440   1.470   1.617
88    G         0.302   0.329   0.283   0.167   0.203   0.078   0.103   0.142   0.008
89    A         0.302   0.423   0.332   0.187   0.365   0.204   0.103   0.307   0.102
90    Q        -0.314  -0.404  -0.403  -0.347  -0.465  -0.469  -0.454  -0.561  -0.569
91    Y         1.328   1.350   1.440   1.458   1.486   1.625   1.440   1.470   1.617
92    D         0.641   0.523   0.396   0.653   0.494   0.294   0.660   0.472   0.221
93    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
94    G         0.641   0.523   0.396   0.703   0.550   0.381   0.660   0.472   0.221
95    V        -0.885  -1.007  -0.929  -0.843  -1.021  -0.911  -0.899  -1.018  -0.902
96    K         0.641   0.523   0.396   0.650   0.513   0.325   0.660   0.472   0.221
97    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
98    F        -0.963  -0.971  -0.921  -0.816  -0.814  -0.702  -1.011  -1.000  -0.893
99    F         0.641   0.523   0.396   0.756   0.615   0.432   0.660   0.472   0.221
100   D         1.328   1.350   1.440   1.258   1.285   1.435   1.440   1.470   1.617
101   H         1.328   1.350   1.440   1.501   1.527   1.666   1.440   1.470   1.617
102   H         1.328   1.350   1.440   1.501   1.527   1.666   1.440   1.470   1.617
103   Q         1.328   1.350   1.440   1.480   1.507   1.646   1.440   1.470   1.617
104   R         1.328   1.350   1.440   1.405   1.428   1.575   1.440   1.470   1.617
105   G        -0.449  -0.511  -0.417  -0.622  -0.697  -0.532  -0.677  -0.730  -0.592
106   F         1.328   1.350   1.440   1.332   1.366   1.506   1.440   1.470   1.617
107   F        -1.834  -1.809  -1.672  -1.685  -1.629  -1.478  -1.456  -1.415  -1.228
108   E        -0.314  -0.365  -0.397  -0.348  -0.428  -0.477  -0.454  -0.519  -0.562
109   T         0.641   0.581   0.410   0.823   0.745   0.486   0.660   0.566   0.246
110   F         1.328   1.350   1.440   1.332   1.366   1.506   1.440   1.470   1.617
111   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
112   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
113   N        -0.416  -0.516  -0.435  -0.466  -0.629  -0.563  -0.597  -0.721  -0.612
114   E        -1.517  -1.428  -1.345  -1.529  -1.387  -1.280  -1.345  -1.249  -1.106
115   K        -0.963  -0.949  -0.914  -1.092  -1.080  -0.985  -1.011  -0.986  -0.889
116   Y        -0.014  -0.190  -0.340   0.304   0.071  -0.169  -0.008  -0.251  -0.472
117   K        -1.714  -1.730  -1.653  -1.562  -1.584  -1.482  -1.345  -1.348  -1.213
118   T         1.328   1.350   1.440   1.418   1.443   1.587   1.440   1.470   1.617
119   K         0.641   0.603   0.412   0.650   0.618   0.351   0.660   0.600   0.250
120   L         1.328   1.350   1.440   1.188   1.223   1.370   1.440   1.470   1.617
121   S         1.328   1.350   1.440   1.208   1.261   1.389   1.440   1.470   1.617
122   S         1.328   1.350   1.440   1.208   1.261   1.389   1.440   1.470   1.617
123   A         1.328   1.350   1.440   1.271   1.292   1.448   1.440   1.470   1.617
124   G         1.328   1.350   1.440   1.281   1.304   1.458   1.440   1.470   1.617
125   L         1.328   1.350   1.440   1.188   1.223   1.370   1.440   1.470   1.617
126   I         0.121   0.165   0.243  -0.091  -0.014   0.083  -0.231  -0.158  -0.068
127   F         0.641   0.749   0.424   0.863   0.994   0.548   0.660   0.817   0.272
128   K         0.641   0.523   0.396   0.673   0.545   0.380   0.660   0.472   0.221
129   H         1.328   1.350   1.440   1.501   1.527   1.666   1.440   1.470   1.617
130   Y         0.641   0.749   0.424   0.756   0.888   0.476   0.660   0.817   0.272
131   G         1.328   1.350   1.440   1.281   1.304   1.458   1.440   1.470   1.617
132   R         0.121   0.174   0.249  -0.113  -0.024   0.083  -0.231  -0.141  -0.056
133   D        -0.314  -0.404  -0.403  -0.405  -0.541  -0.567  -0.454  -0.561  -0.569
134   I         0.302   0.251   0.274   0.242   0.155   0.149   0.103   0.002  -0.007
135   I         1.328   1.350   1.440   1.326   1.365   1.500   1.440   1.470   1.617
136   K        -1.398  -1.410  -1.329  -1.355  -1.361  -1.211  -1.234  -1.232  -1.091
137   T        -1.714  -1.603  -1.634  -1.473  -1.344  -1.362  -1.345  -1.236  -1.198
138   I        -0.963  -0.983  -0.925  -1.059  -1.078  -1.016  -1.011  -1.013  -0.899
139   L         0.580   0.671   0.401   0.509   0.631   0.252   0.567   0.703   0.231
140   N        -1.098  -0.986  -0.948  -1.130  -0.960  -0.910  -1.135  -1.011  -0.921
141   N        -1.098  -1.039  -0.959  -1.127  -1.045  -0.936  -1.135  -1.056  -0.931
142   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
143   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
144   -        -0.597  -0.569  -0.450  -0.801  -0.759  -0.588  -0.841  -0.798  -0.632
145   K        -1.398  -1.360  -1.315  -1.514  -1.452  -1.396  -1.234  -1.187  -1.079
146   V        -1.398  -1.365  -1.318  -1.399  -1.358  -1.315  -1.234  -1.192  -1.082
147   S        -0.963  -0.949  -0.917  -1.026  -0.993  -0.947  -1.011  -0.985  -0.891
148   S        -1.201  -1.156  -0.981  -1.399  -1.308  -1.063  -1.234  -1.173  -0.953
149   S        -1.834  -1.769  -1.662  -1.766  -1.675  -1.498  -1.456  -1.385  -1.221
150   D        -0.885  -0.874  -0.903  -0.838  -0.824  -0.848  -0.899  -0.866  -0.870
151   L        -0.646  -0.611  -0.474  -0.942  -0.877  -0.671  -0.899  -0.847  -0.661
152   D        -0.449  -0.507  -0.415  -0.666  -0.742  -0.594  -0.677  -0.723  -0.590
153   L        -0.014   0.026  -0.298   0.022   0.078  -0.362  -0.008   0.044  -0.413
154   L         0.641   0.523   0.396   0.593   0.447   0.255   0.660   0.472   0.221
155   Y         0.641   0.523   0.396   0.893   0.750   0.574   0.660   0.472   0.221
156   D        -0.885  -0.981  -0.927  -0.850  -0.983  -0.895  -0.899  -0.997  -0.900
157   K         0.641   0.701   0.418   0.650   0.736   0.360   0.660   0.748   0.260
158   V        -0.314  -0.399  -0.402  -0.352  -0.475  -0.524  -0.454  -0.554  -0.568
159   Y         1.328   1.350   1.440   1.458   1.486   1.625   1.440   1.470   1.617
160   K        -0.631  -0.735  -0.874  -0.527  -0.668  -0.899  -0.565  -0.690  -0.835
161   Q        -1.082  -1.087  -0.961  -1.132  -1.159  -0.996  -1.122  -1.108  -0.934
162   F         1.328   1.350   1.440   1.332   1.366   1.506   1.440   1.470   1.617
163   V         0.121   0.196   0.254  -0.091   0.042   0.104  -0.231  -0.100  -0.046
164   E         1.328   1.350   1.440   1.260   1.289   1.437   1.440   1.470   1.617
165   A        -0.314  -0.273  -0.371  -0.413  -0.334  -0.520  -0.454  -0.376  -0.521
166   L         0.641   0.581   0.410   0.593   0.526   0.278   0.660   0.566   0.246
167   D         1.328   1.350   1.440   1.258   1.285   1.435   1.440   1.470   1.617
168   A         1.328   1.350   1.440   1.271   1.292   1.448   1.440   1.470   1.617
169   N         0.641   0.523   0.396   0.849   0.716   0.525   0.660   0.472   0.221
170   D         1.328   1.350   1.440   1.258   1.285   1.435   1.440   1.470   1.617
171   N         1.328   1.350   1.440   1.420   1.461   1.589   1.440   1.470   1.617
172   G         1.328   1.350   1.440   1.281   1.304   1.458   1.440   1.470   1.617
173   I         1.328   1.350   1.440   1.326   1.365   1.500   1.440   1.470   1.617
174   S        -0.885  -0.837  -0.886  -0.967  -0.870  -0.955  -0.899  -0.825  -0.853
175   K        -1.834  -1.861  -1.684  -1.631  -1.662  -1.407  -1.456  -1.450  -1.237
176   Y         0.641   0.701   0.418   0.863   0.939   0.537   0.660   0.748   0.260
177   T        -1.517  -1.414  -1.342  -1.528  -1.402  -1.269  -1.345  -1.246  -1.103
178   I        -2.150  -2.122  -1.959  -2.022  -2.006  -1.752  -1.568  -1.526  -1.322
179   P        -0.416  -0.344  -0.409  -0.502  -0.406  -0.500  -0.597  -0.512  -0.578
180   K        -1.102  -1.122  -0.977  -1.270  -1.306  -1.094  -1.127  -1.138  -0.949
181   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
182   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
183   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
184   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
185   N        -1.098  -1.034  -0.953  -1.235  -1.153  -1.012  -1.135  -1.055  -0.925
186   L        -0.885  -0.960  -0.915  -0.985  -1.076  -1.025  -0.899  -0.957  -0.884
187   E        -1.398  -1.262  -1.312  -1.399  -1.228  -1.262  -1.234  -1.107  -1.076
188   P         0.302   0.270   0.264   0.332   0.264   0.187   0.103   0.036  -0.026
189   N        -0.885  -0.874  -0.909  -0.886  -0.880  -0.910  -0.899  -0.892  -0.881
190   F         1.328   1.350   1.440   1.332   1.366   1.506   1.440   1.470   1.617
191   R        -1.398  -1.253  -1.309  -1.379  -1.197  -1.220  -1.234  -1.097  -1.074
192   D        -0.777  -0.918  -0.925  -0.656  -0.857  -0.864  -0.743  -0.910  -0.893
193   N        -1.834  -1.858  -1.680  -1.702  -1.750  -1.494  -1.456  -1.448  -1.233
194   A        -0.569  -0.554  -0.460  -0.718  -0.730  -0.572  -0.788  -0.772  -0.642
195   I        -0.014  -0.171  -0.332   0.183  -0.013  -0.245  -0.008  -0.225  -0.461
196   S         0.121   0.174   0.249  -0.054   0.046   0.117  -0.231  -0.141  -0.056
197   I         0.302   0.423   0.332   0.115   0.305   0.146   0.103   0.307   0.102
198   P         0.641   0.523   0.396   0.841   0.681   0.469   0.660   0.472   0.221
199   G        -1.082  -1.073  -0.958  -1.304  -1.285  -1.112  -1.122  -1.096  -0.931
200   I        -0.885  -0.914  -0.923  -0.765  -0.808  -0.828  -0.899  -0.941  -0.896
201   I         0.121   0.209   0.266  -0.091   0.065   0.126  -0.231  -0.076  -0.024
202   S         0.641   0.523   0.396   0.607   0.473   0.257   0.660   0.472   0.221
203   G        -0.885  -0.895  -0.898  -0.788  -0.784  -0.825  -0.899  -0.882  -0.864
204   M        -0.646  -0.568  -0.456  -0.817  -0.710  -0.525  -0.899  -0.795  -0.639
205   N         0.641   0.603   0.412   0.805   0.769   0.446   0.660   0.600   0.250
206   P         0.302   0.212   0.261   0.347   0.167   0.203   0.103  -0.070  -0.034
207   N        -1.398  -1.429  -1.329  -1.430  -1.455  -1.332  -1.234  -1.245  -1.092
208   W         0.641   0.581   0.410   0.945   0.870   0.592   0.660   0.566   0.246
209   N         0.641   0.581   0.410   0.812   0.748   0.457   0.660   0.566   0.246
210   E        -1.714  -1.696  -1.645  -1.632  -1.632  -1.576  -1.345  -1.317  -1.206
211   D        -0.963  -0.939  -0.917  -1.087  -1.039  -0.990  -1.011  -0.972  -0.890
212   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
213   T        -1.500  -1.430  -1.347  -1.238  -1.144  -1.022  -1.325  -1.244  -1.105
214   S        -0.416  -0.404  -0.403  -0.563  -0.521  -0.542  -0.597  -0.558  -0.564
215   D         0.580   0.681   0.395   0.582   0.708   0.304   0.567   0.719   0.219
216   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
219   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   E        -0.963  -1.002  -0.927  -1.061  -1.104  -0.971  -1.011  -1.025  -0.900
222   S        -1.517  -1.397  -1.349  -1.574  -1.408  -1.332  -1.345  -1.228  -1.108
223   F        -0.885  -0.960  -0.913  -0.710  -0.814  -0.783  -0.899  -0.958  -0.884
224   D        -0.014  -0.011  -0.305   0.075   0.072  -0.346  -0.008  -0.004  -0.422
225   R        -1.834  -1.807  -1.666  -1.657  -1.666  -1.426  -1.456  -1.413  -1.224
226   C        -1.398  -1.365  -1.319  -1.025  -0.993  -0.931  -1.234  -1.191  -1.082
227   F         1.328   1.350   1.440   1.332   1.366   1.506   1.440   1.470   1.617
228   A        -1.834  -1.812  -1.667  -1.733  -1.687  -1.505  -1.456  -1.418  -1.225
229   R        -1.398  -1.419  -1.328  -1.280  -1.295  -1.148  -1.234  -1.230  -1.089
230   A         0.302   0.411   0.323   0.157   0.326   0.151   0.103   0.285   0.086
231   S         1.328   1.350   1.440   1.208   1.261   1.389   1.440   1.470   1.617
232   E        -1.398  -1.281  -1.308  -1.275  -1.073  -1.179  -1.234  -1.097  -1.071
233   F        -0.885  -0.865  -0.902  -0.907  -0.862  -0.885  -0.899  -0.855  -0.869
234   I         0.064   0.093   0.227  -0.023   0.026   0.221  -0.342  -0.297  -0.100
235   G         1.328   1.350   1.440   1.281   1.304   1.458   1.440   1.470   1.617
236   G        -0.885  -0.788  -0.897  -0.755  -0.653  -0.795  -0.899  -0.798  -0.869
237   V        -1.201  -1.306  -1.312  -0.977  -1.148  -1.159  -1.011  -1.114  -1.072
238   F         1.328   1.350   1.440   1.332   1.366   1.506   1.440   1.470   1.617
239   V        -0.631  -0.751  -0.879  -0.427  -0.602  -0.794  -0.565  -0.711  -0.840
240   T        -1.517  -1.394  -1.345  -1.440  -1.259  -1.187  -1.345  -1.228  -1.105
241   L        -0.014  -0.171  -0.332  -0.023  -0.239  -0.515  -0.008  -0.225  -0.461
242   V         0.121   0.143   0.236  -0.164  -0.134  -0.016  -0.231  -0.201  -0.081
243   R        -1.714  -1.703  -1.644  -1.519  -1.524  -1.429  -1.345  -1.324  -1.206
244   G        -0.631  -0.826  -0.894  -0.395  -0.659  -0.727  -0.565  -0.795  -0.858
245   Y         0.641   0.581   0.410   0.855   0.775   0.504   0.660   0.566   0.246
246   G        -0.885  -0.921  -0.912  -0.879  -0.939  -0.913  -0.899  -0.929  -0.883
247   Q        -1.398  -1.338  -1.319  -1.368  -1.284  -1.211  -1.234  -1.164  -1.082
248   S        -0.014  -0.190  -0.340   0.014  -0.211  -0.474  -0.008  -0.251  -0.472
249   W         1.328   1.350   1.440   1.544   1.573   1.707   1.440   1.470   1.617
250   L         0.641   0.742   0.421   0.593   0.722   0.297   0.660   0.807   0.268
251   P         1.328   1.350   1.440   1.443   1.470   1.611   1.440   1.470   1.617
252   A         1.328   1.350   1.440   1.271   1.292   1.448   1.440   1.470   1.617
253   K         0.302   0.212   0.261   0.185   0.040   0.101   0.103  -0.070  -0.034
254   A        -1.517  -1.498  -1.347  -1.516  -1.487  -1.252  -1.345  -1.305  -1.107
255   L        -0.885  -0.956  -0.919  -0.987  -1.072  -1.039  -0.899  -0.953  -0.888
256   V         0.641   0.603   0.412   0.704   0.659   0.370   0.660   0.600   0.250
257   A        -1.517  -1.512  -1.350  -1.588  -1.581  -1.340  -1.345  -1.312  -1.109
258   Q        -2.150  -2.082  -1.945  -1.828  -1.728  -1.538  -1.568  -1.500  -1.313
259   A         1.328   1.350   1.440   1.271   1.292   1.448   1.440   1.470   1.617
260   I        -1.082  -1.088  -0.948  -1.119  -1.097  -0.903  -1.122  -1.102  -0.921
261   D        -1.517  -1.511  -1.348  -1.599  -1.589  -1.365  -1.345  -1.311  -1.108
262   E        -1.834  -1.717  -1.667  -1.738  -1.587  -1.526  -1.456  -1.344  -1.225
263   R         0.302   0.251   0.274   0.307   0.196   0.196   0.103   0.002  -0.007
264   M        -1.363  -1.383  -1.337  -1.255  -1.328  -1.269  -1.179  -1.195  -1.096
265   D        -1.002  -0.988  -0.921  -1.120  -1.098  -0.995  -1.034  -0.998  -0.892
266   V        -0.777  -0.918  -0.925  -0.607  -0.802  -0.823  -0.743  -0.910  -0.893
267   D         0.580   0.489   0.382   0.574   0.443   0.274   0.567   0.417   0.196
268   K        -0.569  -0.580  -0.472  -0.827  -0.857  -0.704  -0.788  -0.801  -0.658
269   S        -0.314  -0.424  -0.419  -0.459  -0.634  -0.641  -0.454  -0.614  -0.590
270   G        -0.014  -0.119  -0.315   0.106  -0.035  -0.326  -0.008  -0.151  -0.436
271   K        -1.082  -1.077  -0.962  -1.175  -1.137  -0.959  -1.122  -1.100  -0.935
272   I         0.641   0.581   0.410   0.750   0.689   0.448   0.660   0.566   0.246
273   I         0.064   0.107   0.233  -0.289  -0.220  -0.025  -0.342  -0.268  -0.087
274   V        -0.569  -0.562  -0.464  -0.739  -0.734  -0.608  -0.788  -0.776  -0.646
275   L        -0.014  -0.119  -0.315   0.004  -0.130  -0.426  -0.008  -0.151  -0.436
276   P        -1.201  -1.126  -1.285  -1.033  -0.960  -1.170  -1.011  -0.931  -1.048
277   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
278   Q        -0.314  -0.272  -0.382  -0.169  -0.129  -0.308  -0.454  -0.405  -0.540
279   F         0.302   0.212   0.261   0.216   0.051   0.073   0.103  -0.070  -0.034
280   C        -0.014  -0.171  -0.332   0.382   0.158  -0.139  -0.008  -0.225  -0.461
281   P         0.641   0.581   0.410   0.869   0.797   0.560   0.660   0.566   0.246
282   W         1.328   1.350   1.440   1.544   1.573   1.707   1.440   1.470   1.617
283   K         1.328   1.350   1.440   1.234   1.275   1.413   1.440   1.470   1.617
284   E        -0.314  -0.424  -0.419  -0.405  -0.606  -0.594  -0.454  -0.614  -0.590
285   H         1.328   1.350   1.440   1.501   1.527   1.666   1.440   1.470   1.617
286   L         1.328   1.350   1.440   1.188   1.223   1.370   1.440   1.470   1.617
287   Y         0.121   0.122   0.232   0.044   0.029   0.177  -0.231  -0.240  -0.090
288   E        -1.834  -1.726  -1.671  -1.659  -1.492  -1.424  -1.456  -1.349  -1.227
289   L        -0.569  -0.522  -0.458  -0.761  -0.687  -0.635  -0.788  -0.722  -0.639
290   E         1.328   1.350   1.440   1.260   1.289   1.437   1.440   1.470   1.617
291   R        -0.569  -0.562  -0.462  -0.767  -0.776  -0.617  -0.788  -0.782  -0.644
292   E        -0.014   0.127  -0.289   0.057   0.237  -0.361  -0.008   0.183  -0.400
293   K        -1.714  -1.686  -1.651  -1.558  -1.548  -1.475  -1.345  -1.309  -1.211
294   N        -0.449  -0.340  -0.394  -0.561  -0.396  -0.471  -0.677  -0.518  -0.560
295   I        -0.631  -0.601  -0.859  -0.472  -0.441  -0.868  -0.565  -0.536  -0.817
296   E        -0.014  -0.075  -0.321   0.117   0.030  -0.285  -0.008  -0.099  -0.446
297   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
298   K        -0.885  -0.900  -0.910  -0.817  -0.833  -0.839  -0.899  -0.914  -0.881
299   Q        -1.714  -1.697  -1.653  -1.393  -1.395  -1.386  -1.345  -1.319  -1.213
300   I        -0.314  -0.456  -0.418  -0.309  -0.522  -0.491  -0.454  -0.642  -0.590
301   E        -0.646  -0.641  -0.481  -1.008  -1.009  -0.765  -0.899  -0.884  -0.670
302   F         0.121   0.097   0.227   0.001  -0.042   0.159  -0.231  -0.288  -0.100
303   V         0.641   0.603   0.412   0.704   0.659   0.370   0.660   0.600   0.250
304   L         0.302   0.312   0.280   0.115   0.132   0.054   0.103   0.113   0.003
305   F         0.121   0.097   0.227   0.001  -0.042   0.159  -0.231  -0.288  -0.100
306   T        -1.398  -1.273  -1.308  -1.229  -1.026  -1.100  -1.234  -1.090  -1.072
307   D         0.580   0.424   0.361   0.580   0.354   0.239   0.567   0.308   0.156
308   S        -0.416  -0.527  -0.438  -0.559  -0.709  -0.590  -0.597  -0.737  -0.616
309   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
310   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
311   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
312   S        -0.631  -0.826  -0.894  -0.546  -0.811  -0.938  -0.565  -0.795  -0.858
313   G        -1.714  -1.755  -1.660  -1.611  -1.715  -1.585  -1.345  -1.368  -1.218
314   A        -1.082  -1.011  -0.951  -1.280  -1.183  -1.067  -1.122  -1.043  -0.925
315   W        -0.014  -0.031  -0.304   0.377   0.349  -0.063  -0.008  -0.033  -0.422
316   R         1.328   1.350   1.440   1.405   1.428   1.575   1.440   1.470   1.617
317   V         0.641   0.711   0.418   0.711   0.804   0.399   0.660   0.763   0.261
318   S         0.121   0.097   0.227  -0.094  -0.108   0.090  -0.231  -0.288  -0.100
319   T        -0.314  -0.456  -0.418  -0.194  -0.413  -0.357  -0.454  -0.642  -0.590
320   V         1.328   1.350   1.440   1.306   1.339   1.482   1.440   1.470   1.617
321   P        -0.449  -0.467  -0.412  -0.514  -0.506  -0.433  -0.677  -0.677  -0.585
322   I        -0.646  -0.640  -0.480  -0.878  -0.874  -0.635  -0.899  -0.882  -0.669
323   N        -1.201  -1.156  -1.281  -0.938  -0.890  -1.131  -1.011  -0.958  -1.043
324   S        -0.631  -0.826  -0.894  -0.546  -0.813  -0.938  -0.565  -0.795  -0.858
325   T        -0.014  -0.190  -0.340   0.205  -0.050  -0.335  -0.008  -0.251  -0.472
326   S         0.641   0.581   0.410   0.605   0.551   0.277   0.660   0.566   0.246
327   F         1.328   1.350   1.440   1.332   1.366   1.506   1.440   1.470   1.617
328   Q        -1.398  -1.389  -1.322  -1.237  -1.213  -1.153  -1.234  -1.201  -1.083
329   F        -0.314  -0.424  -0.419  -0.297  -0.477  -0.454  -0.454  -0.614  -0.590
330   R         1.328   1.350   1.440   1.405   1.428   1.575   1.440   1.470   1.617
331   R        -0.449  -0.345  -0.401  -0.705  -0.552  -0.586  -0.677  -0.545  -0.571
332   G         0.121   0.097   0.227  -0.051  -0.100   0.114  -0.231  -0.288  -0.100
333   L         1.328   1.350   1.440   1.188   1.223   1.370   1.440   1.470   1.617
334   P         1.328   1.350   1.440   1.443   1.470   1.611   1.440   1.470   1.617
335   E         0.641   0.760   0.424   0.687   0.826   0.419   0.660   0.833   0.273
336   P        -1.398  -1.368  -1.323  -1.242  -1.230  -1.157  -1.234  -1.194  -1.086
337   L         0.064   0.114   0.237  -0.126  -0.000   0.171  -0.342  -0.256  -0.080
338   R         1.328   1.350   1.440   1.405   1.428   1.575   1.440   1.470   1.617
339   G         1.328   1.350   1.440   1.281   1.304   1.458   1.440   1.470   1.617
340   L        -0.314  -0.408  -0.403  -0.437  -0.559  -0.565  -0.454  -0.567  -0.568
341   R         1.328   1.350   1.440   1.405   1.428   1.575   1.440   1.470   1.617
342   D         1.328   1.350   1.440   1.258   1.285   1.435   1.440   1.470   1.617
343   E         0.302   0.430   0.312   0.235   0.417   0.244   0.103   0.318   0.064
344   E         0.302   0.222   0.261   0.154   0.003   0.028   0.103  -0.052  -0.034
345   L         1.328   1.350   1.440   1.188   1.223   1.370   1.440   1.470   1.617
346   S         0.641   0.523   0.396   0.603   0.469   0.248   0.660   0.472   0.221
347   T        -0.014   0.162  -0.288   0.082   0.301  -0.308  -0.008   0.230  -0.398
348   K        -0.314  -0.408  -0.403  -0.448  -0.571  -0.608  -0.454  -0.567  -0.568
349   S         0.121   0.112   0.229  -0.128  -0.131   0.046  -0.231  -0.259  -0.096
350   G         0.641   0.523   0.396   0.709   0.557   0.395   0.660   0.472   0.221
351   V        -0.449  -0.349  -0.396  -0.599  -0.424  -0.511  -0.677  -0.530  -0.562
352   P        -0.631  -0.609  -0.853  -0.322  -0.294  -0.695  -0.565  -0.545  -0.811
353   G        -0.014   0.173  -0.282   0.068   0.304  -0.350  -0.008   0.244  -0.389
354   C         0.302   0.212   0.261   0.474   0.292   0.310   0.103  -0.070  -0.034
355   I         0.064   0.098   0.229  -0.203  -0.142   0.056  -0.342  -0.286  -0.095
356   F         1.328   1.350   1.440   1.332   1.366   1.506   1.440   1.470   1.617
357   I         0.064   0.114   0.237  -0.203  -0.112   0.071  -0.342  -0.256  -0.080
358   H         1.328   1.350   1.440   1.501   1.527   1.666   1.440   1.470   1.617
359   A         1.328   1.350   1.440   1.271   1.292   1.448   1.440   1.470   1.617
360   A         0.641   0.603   0.412   0.659   0.606   0.316   0.660   0.600   0.250
361   G         1.328   1.350   1.440   1.281   1.304   1.458   1.440   1.470   1.617
362   F         1.328   1.350   1.440   1.332   1.366   1.506   1.440   1.470   1.617
363   I         1.328   1.350   1.440   1.326   1.365   1.500   1.440   1.470   1.617
364   G         1.328   1.350   1.440   1.281   1.304   1.458   1.440   1.470   1.617
365   G         1.328   1.350   1.440   1.281   1.304   1.458   1.440   1.470   1.617
366   A         0.121   0.097   0.227  -0.072  -0.115   0.091  -0.231  -0.288  -0.100
367   K        -0.314  -0.268  -0.367  -0.328  -0.232  -0.372  -0.454  -0.368  -0.514
368   S        -0.014   0.124  -0.286   0.235   0.410  -0.175  -0.008   0.179  -0.395
369   K        -1.398  -1.368  -1.333  -1.357  -1.330  -1.238  -1.234  -1.199  -1.095
370   E         0.064   0.092   0.227  -0.288  -0.248  -0.029  -0.342  -0.298  -0.100
371   A        -0.646  -0.561  -0.466  -0.957  -0.815  -0.684  -0.899  -0.780  -0.650
372   V         0.064   0.115   0.240  -0.243  -0.164   0.037  -0.342  -0.253  -0.074
373   Y        -0.314  -0.173  -0.357  -0.386  -0.181  -0.432  -0.454  -0.245  -0.500
374   E        -1.201  -1.154  -1.280  -1.056  -1.013  -1.199  -1.011  -0.958  -1.043
375   L         0.121   0.097   0.227  -0.071  -0.084   0.127  -0.231  -0.288  -0.100
376   A         1.328   1.350   1.440   1.271   1.292   1.448   1.440   1.470   1.617
377   K         0.302   0.342   0.288   0.185   0.252   0.147   0.103   0.167   0.019
378   M        -0.646  -0.556  -0.461  -0.800  -0.675  -0.550  -0.899  -0.775  -0.643
379   S        -0.314  -0.433  -0.419  -0.449  -0.638  -0.626  -0.454  -0.622  -0.591
380   L         0.641   0.581   0.410   0.585   0.513   0.258   0.660   0.566   0.246
381   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
382   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
383   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
384   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
385   A        -1.102  -1.072  -0.954  -1.241  -1.201  -1.030  -1.127  -1.082  -0.924
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P40093
Output conservation file - output/P40093
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
