1     M         1.930   1.938   1.958   2.169   2.186   2.214   2.095   2.104   2.131
2     A         0.143   0.105   0.092   0.271   0.206   0.189   0.036  -0.025  -0.047
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     R        -0.016  -0.012   0.007  -0.043  -0.037  -0.006  -0.221  -0.214  -0.186
7     R         1.930   1.938   1.958   1.966   1.980   2.010   2.095   2.104   2.131
8     P        -0.016  -0.012   0.007  -0.192  -0.186  -0.156  -0.221  -0.214  -0.186
9     D        -0.016  -0.012   0.007  -0.211  -0.205  -0.175  -0.221  -0.214  -0.186
10    N         1.930   1.938   1.958   1.825   1.839   1.869   2.095   2.104   2.131
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    Q        -0.016  -0.012   0.007   0.206   0.213   0.244  -0.221  -0.214  -0.186
19    N         1.930   1.938   1.958   1.825   1.839   1.869   2.095   2.104   2.131
20    P        -0.016  -0.012   0.007  -0.043  -0.037  -0.006  -0.221  -0.214  -0.186
21    E        -0.016  -0.012   0.007  -0.317  -0.312  -0.281  -0.221  -0.214  -0.186
22    G        -0.016  -0.012   0.007  -0.098  -0.092  -0.062  -0.221  -0.214  -0.186
23    E        -0.016  -0.012   0.007  -0.192  -0.186  -0.156  -0.221  -0.214  -0.186
24    N        -0.016  -0.012   0.007  -0.327  -0.321  -0.291  -0.221  -0.214  -0.186
25    L        -0.016  -0.012   0.007  -0.173  -0.167  -0.137  -0.221  -0.214  -0.186
26    R         1.930   1.938   1.958   1.966   1.980   2.010   2.095   2.104   2.131
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    I         1.930   1.938   1.958   2.067   2.081   2.111   2.095   2.104   2.131
35    K        -0.016  -0.012   0.007  -0.145  -0.139  -0.108  -0.221  -0.214  -0.186
36    R         1.930   1.938   1.958   1.966   1.980   2.010   2.095   2.104   2.131
37    V        -0.016  -0.012   0.007  -0.080  -0.074  -0.043  -0.221  -0.214  -0.186
38    R         1.930   1.938   1.958   1.966   1.980   2.010   2.095   2.104   2.131
39    L        -0.016  -0.012   0.007  -0.278  -0.273  -0.242  -0.221  -0.214  -0.186
40    E        -0.016  -0.012   0.007  -0.425  -0.421  -0.390  -0.221  -0.214  -0.186
41    S        -0.016  -0.012   0.007  -0.268  -0.263  -0.232  -0.221  -0.214  -0.186
42    V         1.930   1.938   1.958   1.953   1.967   1.997   2.095   2.104   2.131
43    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    Q        -0.016  -0.012   0.007  -0.192  -0.186  -0.156  -0.221  -0.214  -0.186
45    N         1.930   1.938   1.958   1.825   1.839   1.869   2.095   2.104   2.131
46    D        -0.016  -0.012   0.007  -0.297  -0.292  -0.261  -0.221  -0.214  -0.186
47    E        -0.016  -0.012   0.007  -0.317  -0.312  -0.281  -0.221  -0.214  -0.186
48    E        -0.016  -0.012   0.007  -0.145  -0.139  -0.108  -0.221  -0.214  -0.186
49    E        -0.016  -0.012   0.007  -0.376  -0.371  -0.340  -0.221  -0.214  -0.186
50    E        -1.154  -1.149  -1.135  -1.136  -1.108  -1.103  -0.993  -0.983  -0.958
51    N        -1.154  -1.149  -1.135  -1.027  -1.011  -0.994  -0.993  -0.983  -0.958
52    E         0.143   0.105   0.092  -0.112  -0.162  -0.179   0.036  -0.025  -0.047
53    V         0.143   0.171   0.127   0.093   0.141   0.061   0.036   0.081   0.010
54    S         0.143   0.171   0.127   0.103   0.140   0.085   0.036   0.081   0.010
55    R         0.143   0.171   0.119  -0.157  -0.108  -0.192   0.036   0.081  -0.003
56    T        -1.154  -1.149  -1.135  -0.971  -0.974  -0.937  -0.993  -0.983  -0.958
57    Q         0.143   0.171   0.119   0.290   0.333   0.253   0.036   0.081  -0.003
58    N        -1.154  -1.149  -1.135  -0.984  -0.980  -0.950  -0.993  -0.983  -0.958
59    I        -1.154  -1.149  -1.135  -1.175  -1.174  -1.142  -0.993  -0.983  -0.958
60    V         0.143   0.105   0.092   0.299   0.248   0.236   0.036  -0.025  -0.047
61    T         0.143   0.171   0.119   0.239   0.281   0.198   0.036   0.081  -0.003
62    D        -1.154  -1.149  -1.135  -1.228  -1.226  -1.195  -0.993  -0.983  -0.958
63    N        -1.154  -1.149  -1.135  -1.078  -1.059  -1.045  -0.993  -0.983  -0.958
64    R        -1.154  -1.149  -1.135  -0.953  -0.947  -0.919  -0.993  -0.983  -0.958
65    H        -1.154  -1.149  -1.135  -0.922  -0.921  -0.888  -0.993  -0.983  -0.958
66    D         0.143   0.105   0.092  -0.042  -0.109  -0.135   0.036  -0.025  -0.047
67    S         0.143   0.105   0.092  -0.132  -0.208  -0.239   0.036  -0.025  -0.047
68    P        -1.154  -1.149  -1.135  -1.130  -1.127  -1.096  -0.993  -0.983  -0.958
69    E         0.143   0.171   0.127  -0.072  -0.026  -0.087   0.036   0.081   0.010
70    A         0.143   0.171   0.119   0.065   0.102   0.031   0.036   0.081  -0.003
71    V        -1.154  -1.149  -1.135  -1.009  -1.005  -0.975  -0.993  -0.983  -0.958
72    V        -1.154  -1.149  -1.135  -0.996  -0.988  -0.962  -0.993  -0.983  -0.958
73    E        -1.154  -1.149  -1.135  -1.275  -1.257  -1.242  -0.993  -0.983  -0.958
74    I         0.143   0.105   0.092   0.216   0.146   0.122   0.036  -0.025  -0.047
75    I         0.143   0.171   0.119   0.193   0.237   0.157   0.036   0.081  -0.003
76    G        -1.154  -1.149  -1.135  -1.104  -1.085  -1.070  -0.993  -0.983  -0.958
77    E         0.143   0.105   0.092  -0.112  -0.162  -0.179   0.036  -0.025  -0.047
78    R         1.930   1.938   1.958   1.927   1.942   1.971   2.095   2.104   2.131
79    A         0.143   0.171   0.119   0.065   0.102   0.031   0.036   0.081  -0.003
80    L         0.143   0.171   0.127   0.112   0.155   0.084   0.036   0.081   0.010
81    E        -1.154  -1.149  -1.135  -1.364  -1.344  -1.332  -0.993  -0.983  -0.958
82    N        -1.154  -1.149  -1.135  -1.399  -1.399  -1.367  -0.993  -0.983  -0.958
83    T        -1.154  -1.149  -1.135  -0.898  -0.896  -0.863  -0.993  -0.983  -0.958
84    S        -1.154  -1.149  -1.135  -0.990  -0.982  -0.956  -0.993  -0.983  -0.958
85    E         0.143   0.171   0.119  -0.132  -0.083  -0.186   0.036   0.081  -0.003
86    E         1.930   1.938   1.958   1.601   1.621   1.643   2.095   2.104   2.131
87    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
88    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
89    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
90    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
91    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
92    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
93    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
94    L         0.143   0.171   0.127   0.248   0.288   0.231   0.036   0.081   0.010
95    F        -0.016  -0.012   0.007   0.177   0.185   0.215  -0.221  -0.214  -0.186
96    R        -0.016  -0.012   0.007  -0.115  -0.109  -0.079  -0.221  -0.214  -0.186
97    A        -0.016  -0.012   0.007   0.089   0.095   0.126  -0.221  -0.214  -0.186
98    L         1.930   1.938   1.958   1.950   1.963   1.994   2.095   2.104   2.131
99    E        -0.016  -0.012   0.007  -0.286  -0.280  -0.249  -0.221  -0.214  -0.186
100   E        -0.016  -0.012   0.007  -0.566  -0.562  -0.531  -0.221  -0.214  -0.186
101   D         1.930   1.938   1.958   1.718   1.731   1.761   2.095   2.104   2.131
102   P        -0.016  -0.012   0.007  -0.329  -0.324  -0.293  -0.221  -0.214  -0.186
103   G        -0.016  -0.012   0.007  -0.168  -0.162  -0.131  -0.221  -0.214  -0.186
104   S         1.930   1.938   1.958   1.849   1.863   1.893   2.095   2.104   2.131
105   D        -1.154  -1.149  -1.135  -1.015  -1.002  -0.981  -0.993  -0.983  -0.958
106   H        -1.154  -1.149  -1.135  -0.825  -0.816  -0.791  -0.993  -0.983  -0.958
107   N         0.143   0.171   0.119  -0.182  -0.134  -0.219   0.036   0.081  -0.003
108   T         0.143   0.105   0.092   0.016  -0.059  -0.096   0.036  -0.025  -0.047
109   S         0.143   0.105   0.092   0.031  -0.035  -0.049   0.036  -0.025  -0.047
110   -        -0.016  -0.012   0.007  -0.077  -0.071  -0.040  -0.221  -0.214  -0.186
111   N        -1.154  -1.149  -1.135  -1.130  -1.122  -1.096  -0.993  -0.983  -0.958
112   N        -1.154  -1.149  -1.135  -1.302  -1.283  -1.270  -0.993  -0.983  -0.958
113   D         0.143   0.105   0.092  -0.132  -0.201  -0.239   0.036  -0.025  -0.047
114   S        -1.154  -1.149  -1.135  -1.059  -1.054  -1.025  -0.993  -0.983  -0.958
115   G        -1.154  -1.149  -1.135  -0.984  -0.990  -0.950  -0.993  -0.983  -0.958
116   N        -1.154  -1.149  -1.135  -1.399  -1.386  -1.367  -0.993  -0.983  -0.958
117   H        -1.154  -1.149  -1.135  -0.898  -0.898  -0.863  -0.993  -0.983  -0.958
118   D         0.143   0.105   0.092  -0.003  -0.066  -0.089   0.036  -0.025  -0.047
119   R        -1.154  -1.149  -1.135  -1.015  -1.004  -0.981  -0.993  -0.983  -0.958
120   E         0.143   0.171   0.119  -0.132  -0.075  -0.186   0.036   0.081  -0.003
121   T        -1.154  -1.149  -1.135  -0.990  -0.984  -0.956  -0.993  -0.983  -0.958
122   M         0.143   0.171   0.119  -0.038   0.007  -0.060   0.036   0.081  -0.003
123   H         0.143   0.105   0.092   0.335   0.261   0.230   0.036  -0.025  -0.047
124   T        -1.154  -1.149  -1.135  -1.351  -1.354  -1.318  -0.993  -0.983  -0.958
125   E        -0.016  -0.012   0.007  -0.329  -0.324  -0.293  -0.221  -0.214  -0.186
126   E        -0.016  -0.012   0.007  -0.384  -0.379  -0.348  -0.221  -0.214  -0.186
127   P        -0.016  -0.012   0.007  -0.043  -0.037  -0.006  -0.221  -0.214  -0.186
128   E        -0.016  -0.012   0.007  -0.395  -0.390  -0.360  -0.221  -0.214  -0.186
129   A        -0.016  -0.012   0.007  -0.126  -0.120  -0.089  -0.221  -0.214  -0.186
130   S        -0.016  -0.012   0.007   0.018   0.025   0.055  -0.221  -0.214  -0.186
131   S        -0.016  -0.012   0.007  -0.126  -0.120  -0.089  -0.221  -0.214  -0.186
132   G        -1.154  -1.149  -1.135  -1.040  -1.034  -1.006  -0.993  -0.983  -0.958
133   N        -1.154  -1.149  -1.135  -0.802  -0.789  -0.767  -0.993  -0.983  -0.958
134   N        -1.154  -1.149  -1.135  -1.399  -1.386  -1.367  -0.993  -0.983  -0.958
135   I        -1.154  -1.149  -1.135  -0.910  -0.909  -0.876  -0.993  -0.983  -0.958
136   T         0.143   0.171   0.119  -0.147  -0.099  -0.180   0.036   0.081  -0.003
137   L        -1.154  -1.149  -1.135  -1.053  -1.053  -1.019  -0.993  -0.983  -0.958
138   T        -1.154  -1.149  -1.135  -1.078  -1.067  -1.045  -0.993  -0.983  -0.958
139   N         0.143   0.171   0.127   0.036   0.081   0.005   0.036   0.081   0.010
140   N        -1.154  -1.149  -1.135  -0.761  -0.751  -0.726  -0.993  -0.983  -0.958
141   V        -1.154  -1.149  -1.135  -1.065  -1.046  -1.032  -0.993  -0.983  -0.958
142   E        -1.154  -1.149  -1.135  -1.399  -1.380  -1.367  -0.993  -0.983  -0.958
143   E         0.143   0.171   0.119  -0.132  -0.075  -0.186   0.036   0.081  -0.003
144   L        -1.154  -1.149  -1.135  -1.104  -1.089  -1.070  -0.993  -0.983  -0.958
145   H         0.143   0.171   0.119   0.150   0.192   0.125   0.036   0.081  -0.003
146   T         0.143   0.171   0.119   0.031   0.077  -0.006   0.036   0.081  -0.003
147   M        -1.154  -1.149  -1.135  -0.867  -0.861  -0.833  -0.993  -0.983  -0.958
148   D        -1.154  -1.149  -1.135  -1.399  -1.380  -1.367  -0.993  -0.983  -0.958
149   V         0.143   0.105   0.092   0.216   0.159   0.139   0.036  -0.025  -0.047
150   L        -1.154  -1.149  -1.135  -1.065  -1.060  -1.032  -0.993  -0.983  -0.958
151   S        -1.154  -1.149  -1.135  -1.027  -1.011  -0.994  -0.993  -0.983  -0.958
152   Q        -1.154  -1.149  -1.135  -0.831  -0.830  -0.797  -0.993  -0.983  -0.958
153   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
154   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
155   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
156   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
157   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
158   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
159   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
160   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
161   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
162   M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
163   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
164   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
165   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
166   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
167   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
168   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
169   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
170   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
171   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
172   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
173   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
174   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
175   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
176   S        -1.154  -1.149  -1.135  -0.990  -0.971  -0.956  -0.993  -0.983  -0.958
177   K         0.143   0.105   0.092   0.160   0.093   0.068   0.036  -0.025  -0.047
178   E        -1.154  -1.149  -1.135  -1.309  -1.295  -1.277  -0.993  -0.983  -0.958
179   Q        -1.154  -1.149  -1.135  -0.825  -0.808  -0.791  -0.993  -0.983  -0.958
180   T        -1.154  -1.149  -1.135  -1.034  -1.028  -1.000  -0.993  -0.983  -0.958
181   V         0.143   0.171   0.119   0.234   0.280   0.193   0.036   0.081  -0.003
182   D         0.143   0.105   0.092  -0.042  -0.109  -0.135   0.036  -0.025  -0.047
183   L         0.143   0.105   0.092   0.141   0.076   0.056   0.036  -0.025  -0.047
184   T         0.143   0.105   0.092   0.016  -0.059  -0.096   0.036  -0.025  -0.047
185   A        -1.154  -1.149  -1.135  -0.990  -0.995  -0.956  -0.993  -0.983  -0.958
186   D        -1.154  -1.149  -1.135  -1.456  -1.441  -1.424  -0.993  -0.983  -0.958
187   A        -1.154  -1.149  -1.135  -1.009  -1.007  -0.975  -0.993  -0.983  -0.958
188   I         0.143   0.105   0.092   0.248   0.183   0.160   0.036  -0.025  -0.047
189   D         0.143   0.171   0.119   0.036   0.081  -0.010   0.036   0.081  -0.003
190   L         0.143   0.105   0.092   0.141   0.076   0.056   0.036  -0.025  -0.047
191   D        -1.154  -1.149  -1.135  -1.399  -1.380  -1.367  -0.993  -0.983  -0.958
192   A         0.143   0.105   0.092   0.169   0.095   0.069   0.036  -0.025  -0.047
193   E         0.143   0.105   0.092  -0.107  -0.154  -0.173   0.036  -0.025  -0.047
194   E         0.143   0.105   0.092  -0.023  -0.062  -0.076   0.036  -0.025  -0.047
195   Q         0.143   0.105   0.092   0.308   0.246   0.224   0.036  -0.025  -0.047
196   Q         1.930   1.938   1.958   2.060   2.074   2.104   2.095   2.104   2.131
197   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
198   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
199   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
200   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
201   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
202   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
203   V         0.143   0.105   0.092   0.267   0.215   0.199   0.036  -0.025  -0.047
204   L        -1.154  -1.149  -1.135  -1.009  -0.997  -0.975  -0.993  -0.983  -0.958
205   Q        -1.154  -1.149  -1.135  -1.275  -1.263  -1.242  -0.993  -0.983  -0.958
206   I         0.143   0.105   0.092   0.234   0.167   0.144   0.036  -0.025  -0.047
207   S        -1.154  -1.149  -1.135  -1.084  -1.081  -1.051  -0.993  -0.983  -0.958
208   D         1.930   1.938   1.958   1.792   1.809   1.836   2.095   2.104   2.131
209   D         0.143   0.171   0.119  -0.223  -0.170  -0.264   0.036   0.081  -0.003
210   D        -1.154  -1.149  -1.135  -1.351  -1.326  -1.318  -0.993  -0.983  -0.958
211   F        -1.154  -1.149  -1.135  -0.940  -0.950  -0.906  -0.993  -0.983  -0.958
212   Q        -1.154  -1.149  -1.135  -0.831  -0.815  -0.797  -0.993  -0.983  -0.958
213   E         0.143   0.171   0.119  -0.132  -0.075  -0.186   0.036   0.081  -0.003
214   E         0.143   0.105   0.092  -0.112  -0.162  -0.179   0.036  -0.025  -0.047
215   T        -1.154  -1.149  -1.135  -1.262  -1.243  -1.229  -0.993  -0.983  -0.958
216   K         0.143   0.171   0.127   0.122   0.171   0.090   0.036   0.081   0.010
217   E        -1.154  -1.149  -1.135  -1.162  -1.136  -1.129  -0.993  -0.983  -0.958
218   A         0.143   0.171   0.119   0.225   0.271   0.188   0.036   0.081  -0.003
219   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   K        -1.154  -1.149  -1.135  -0.892  -0.873  -0.857  -0.993  -0.983  -0.958
221   E         1.930   1.938   1.958   1.601   1.621   1.643   2.095   2.104   2.131
222   Y         0.143   0.105   0.092   0.487   0.423   0.400   0.036  -0.025  -0.047
223   G         0.143   0.171   0.127   0.322   0.371   0.294   0.036   0.081   0.010
224   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
228   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
229   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
230   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
231   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
232   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
233   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
234   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
235   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
236   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
237   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
238   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
239   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
240   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
241   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
242   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
243   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
244   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
245   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
246   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
247   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
248   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
249   A         0.143   0.171   0.119   0.188   0.232   0.152   0.036   0.081  -0.003
250   A        -1.154  -1.149  -1.135  -1.015  -1.011  -0.981  -0.993  -0.983  -0.958
251   K        -1.154  -1.149  -1.135  -0.990  -0.978  -0.956  -0.993  -0.983  -0.958
252   D         1.930   1.938   1.958   1.792   1.809   1.836   2.095   2.104   2.131
253   Y         1.930   1.938   1.958   2.238   2.251   2.283   2.095   2.104   2.131
254   R         0.143   0.171   0.119   0.183   0.232   0.142   0.036   0.081  -0.003
255   C         1.930   1.938   1.958   2.090   2.103   2.134   2.095   2.104   2.131
256   P         0.143   0.105   0.092   0.234   0.166   0.146   0.036  -0.025  -0.047
257   I         1.930   1.938   1.958   2.029   2.042   2.073   2.095   2.104   2.131
258   C         1.930   1.938   1.958   2.090   2.103   2.134   2.095   2.104   2.131
259   F         0.143   0.105   0.092   0.372   0.301   0.276   0.036  -0.025  -0.047
260   E         0.143   0.105   0.092  -0.223  -0.279  -0.309   0.036  -0.025  -0.047
261   P         0.143   0.105   0.092   0.169   0.092   0.069   0.036  -0.025  -0.047
262   P         1.930   1.938   1.958   2.019   2.028   2.063   2.095   2.104   2.131
263   E         0.143   0.171   0.127  -0.223  -0.170  -0.251   0.036   0.081   0.010
264   T        -1.154  -1.149  -1.135  -1.084  -1.082  -1.051  -0.993  -0.983  -0.958
265   A         0.143   0.105   0.092   0.225   0.157   0.135   0.036  -0.025  -0.047
266   L        -1.154  -1.149  -1.135  -1.097  -1.103  -1.064  -0.993  -0.983  -0.958
267   M         0.143   0.105   0.092   0.439   0.379   0.356   0.036  -0.025  -0.047
268   T         1.930   1.938   1.958   1.948   1.960   1.992   2.095   2.104   2.131
269   L         0.143   0.171   0.119   0.225   0.267   0.182   0.036   0.081  -0.003
270   C         1.930   1.938   1.958   2.090   2.103   2.134   2.095   2.104   2.131
271   G         1.930   1.938   1.958   2.100   2.115   2.144   2.095   2.104   2.131
272   H         1.930   1.938   1.958   2.199   2.214   2.244   2.095   2.104   2.131
273   V         0.143   0.105   0.092   0.202   0.143   0.123   0.036  -0.025  -0.047
274   F         1.930   1.938   1.958   2.179   2.192   2.224   2.095   2.104   2.131
275   C         1.930   1.938   1.958   2.090   2.103   2.134   2.095   2.104   2.131
276   C         0.143   0.105   0.092   0.271   0.200   0.176   0.036  -0.025  -0.047
277   P        -1.154  -1.149  -1.135  -1.053  -1.028  -1.019  -0.993  -0.983  -0.958
278   C         1.930   1.938   1.958   2.090   2.103   2.134   2.095   2.104   2.131
279   L         0.143   0.105   0.092   0.183   0.122   0.105   0.036  -0.025  -0.047
280   F         0.143   0.105   0.092   0.372   0.301   0.276   0.036  -0.025  -0.047
281   Q         0.143   0.105   0.092   0.207   0.133   0.106   0.036  -0.025  -0.047
282   M         0.143   0.105   0.092   0.407   0.345   0.320   0.036  -0.025  -0.047
283   V         0.143   0.105   0.092   0.150   0.086   0.063   0.036  -0.025  -0.047
284   N         0.143   0.105   0.092   0.178   0.120   0.107   0.036  -0.025  -0.047
285   S        -1.154  -1.149  -1.135  -1.175  -1.169  -1.142  -0.993  -0.983  -0.958
286   S         0.143   0.105   0.092   0.031  -0.035  -0.049   0.036  -0.025  -0.047
287   R         0.143   0.105   0.092   0.188   0.128   0.109   0.036  -0.025  -0.047
288   T         0.143   0.105   0.092   0.207   0.145   0.127   0.036  -0.025  -0.047
289   C        -1.154  -1.149  -1.135  -0.904  -0.904  -0.870  -0.993  -0.983  -0.958
290   R         0.143   0.105   0.092   0.207   0.149   0.130   0.036  -0.025  -0.047
291   Q         0.143   0.171   0.119   0.244   0.290   0.208   0.036   0.081  -0.003
292   F        -0.016  -0.012   0.007   0.187   0.194   0.225  -0.221  -0.214  -0.186
293   G         1.930   1.938   1.958   2.077   2.091   2.121   2.095   2.104   2.131
294   H        -0.016  -0.012   0.007   0.089   0.095   0.126  -0.221  -0.214  -0.186
295   C         1.930   1.938   1.958   2.090   2.103   2.134   2.095   2.104   2.131
296   A         0.143   0.105   0.092   0.271   0.206   0.189   0.036  -0.025  -0.047
297   L         0.143   0.105   0.092   0.141   0.076   0.056   0.036  -0.025  -0.047
298   C         1.930   1.938   1.958   2.090   2.103   2.134   2.095   2.104   2.131
299   R         1.930   1.938   1.958   1.927   1.942   1.971   2.095   2.104   2.131
300   S        -1.154  -1.149  -1.135  -1.130  -1.121  -1.096  -0.993  -0.983  -0.958
301   K         0.143   0.171   0.127   0.193   0.240   0.166   0.036   0.081   0.010
302   V         0.143   0.171   0.127   0.202   0.247   0.179   0.036   0.081   0.010
303   Y        -1.154  -1.149  -1.135  -0.749  -0.737  -0.714  -0.993  -0.983  -0.958
304   L        -1.154  -1.149  -1.135  -0.873  -0.870  -0.839  -0.993  -0.983  -0.958
305   K         0.143   0.105   0.092   0.160   0.093   0.068   0.036  -0.025  -0.047
306   D        -1.154  -1.149  -1.135  -1.046  -1.033  -1.013  -0.993  -0.983  -0.958
307   V         0.143   0.171   0.127   0.202   0.247   0.179   0.036   0.081   0.010
308   R        -0.016  -0.012   0.007  -0.105  -0.099  -0.068  -0.221  -0.214  -0.186
309   L        -0.016  -0.012   0.007   0.048   0.055   0.086  -0.221  -0.214  -0.186
310   I         0.143   0.171   0.127   0.234   0.280   0.206   0.036   0.081   0.010
311   I        -1.154  -1.149  -1.135  -0.904  -0.891  -0.870  -0.993  -0.983  -0.958
312   L         1.930   1.938   1.958   1.917   1.928   1.961   2.095   2.104   2.131
313   R         0.143   0.105   0.092  -0.003  -0.076  -0.115   0.036  -0.025  -0.047
314   K         0.143   0.105   0.092   0.294   0.243   0.225   0.036  -0.025  -0.047
315   K        -1.154  -1.149  -1.135  -0.892  -0.871  -0.857  -0.993  -0.983  -0.958
316   Q         0.143   0.105   0.092   0.262   0.195   0.171   0.036  -0.025  -0.047
317   V        -0.016  -0.012   0.007   0.038   0.045   0.076  -0.221  -0.214  -0.186
318   K        -0.016  -0.012   0.007  -0.192  -0.186  -0.156  -0.221  -0.214  -0.186
319   K        -0.016  -0.012   0.007   0.029   0.036   0.067  -0.221  -0.214  -0.186
320   K         1.930   1.938   1.958   2.004   2.018   2.048   2.095   2.104   2.131
321   V         0.143   0.171   0.119   0.188   0.237   0.147   0.036   0.081  -0.003
322   K         1.930   1.938   1.958   1.968   1.984   2.012   2.095   2.104   2.131
323   S         0.143   0.171   0.127   0.031   0.070   0.007   0.036   0.081   0.010
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P40072
Output conservation file - output/P40072
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
