1     M         1.226   1.238   1.298   1.406   1.424   1.506   1.304   1.321   1.413
2     S         0.501   0.394   0.198   0.364   0.231  -0.058   0.525   0.365   0.016
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     F        -0.505  -0.617  -0.621  -0.372  -0.549  -0.571  -0.588  -0.741  -0.731
5     F        -0.505  -0.385  -0.568  -0.342  -0.172  -0.424  -0.588  -0.422  -0.658
6     N        -0.992  -0.810  -1.090  -0.838  -0.593  -0.987  -0.877  -0.665  -0.969
7     R        -1.106  -1.055  -1.118  -1.169  -1.088  -1.160  -1.034  -0.963  -0.999
8     S        -0.087  -0.085   0.053  -0.566  -0.566  -0.323  -0.441  -0.445  -0.244
9     N        -0.442  -0.538  -0.608  -0.358  -0.497  -0.677  -0.477  -0.614  -0.710
10    T         0.002   0.055   0.082  -0.275  -0.178  -0.187  -0.279  -0.192  -0.192
11    T        -1.331  -1.271  -1.161  -1.524  -1.432  -1.291  -1.269  -1.203  -1.045
12    S        -0.719  -0.651  -0.635  -1.049  -0.949  -0.899  -0.873  -0.782  -0.749
13    A        -0.719  -0.685  -0.645  -1.049  -1.009  -0.914  -0.873  -0.843  -0.761
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    G        -0.305  -0.195  -0.553  -0.249  -0.097  -0.676  -0.295  -0.152  -0.637
19    T        -0.188  -0.347  -0.551  -0.060  -0.274  -0.607  -0.143  -0.352  -0.635
20    S        -1.647  -1.608  -1.548  -1.717  -1.679  -1.535  -1.368  -1.331  -1.205
21    T        -0.046  -0.064   0.054  -0.372  -0.426  -0.253  -0.366  -0.407  -0.242
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    A        -1.314  -1.283  -1.164  -1.566  -1.533  -1.316  -1.256  -1.224  -1.049
24    M        -0.855  -0.855  -0.672  -1.027  -1.067  -0.797  -1.034  -1.030  -0.793
25    A        -1.647  -1.602  -1.563  -1.645  -1.585  -1.548  -1.368  -1.332  -1.217
26    N        -0.505  -0.461  -0.582  -0.505  -0.427  -0.638  -0.588  -0.513  -0.681
27    E        -1.647  -1.718  -1.570  -1.405  -1.498  -1.335  -1.368  -1.412  -1.222
28    K        -0.855  -0.855  -0.672  -1.032  -1.043  -0.770  -1.034  -1.030  -0.793
29    D         0.145   0.247   0.145   0.128   0.271   0.121  -0.032   0.133  -0.077
30    L         0.501   0.443   0.201   0.699   0.634   0.315   0.525   0.438   0.021
31    A        -1.647  -1.533  -1.545  -1.557  -1.435  -1.395  -1.368  -1.275  -1.202
32    N        -0.188  -0.331  -0.554   0.032  -0.149  -0.510  -0.143  -0.331  -0.639
33    D         0.501   0.573   0.217   0.594   0.675   0.233   0.525   0.625   0.049
34    I        -0.505  -0.617  -0.621  -0.448  -0.621  -0.633  -0.588  -0.741  -0.731
35    V        -0.855  -0.855  -0.672  -0.980  -0.969  -0.697  -1.034  -1.030  -0.793
36    I        -0.647  -0.676  -0.618  -0.666  -0.698  -0.603  -0.811  -0.840  -0.732
37    N        -0.505  -0.635  -0.622  -0.481  -0.690  -0.713  -0.588  -0.756  -0.732
38    S        -0.505  -0.513  -0.604  -0.470  -0.506  -0.677  -0.588  -0.627  -0.709
39    P         0.501   0.548   0.213   0.637   0.695   0.205   0.525   0.590   0.041
40    A        -0.046   0.016   0.086  -0.232  -0.121  -0.043  -0.366  -0.261  -0.184
41    E         0.501   0.573   0.217   0.724   0.813   0.310   0.525   0.625   0.049
42    D         1.226   1.238   1.298   1.181   1.195   1.301   1.304   1.321   1.413
43    S         1.226   1.238   1.298   0.987   1.011   1.123   1.304   1.321   1.413
44    I         0.501   0.443   0.201   0.604   0.542   0.177   0.525   0.438   0.021
45    S         0.501   0.579   0.218   0.401   0.498   0.067   0.525   0.634   0.051
46    D         1.226   1.238   1.298   1.181   1.195   1.301   1.304   1.321   1.413
47    I         0.145   0.067   0.088   0.140   0.021   0.025  -0.032  -0.170  -0.181
48    A        -0.188  -0.180  -0.527  -0.118  -0.107  -0.590  -0.143  -0.136  -0.602
49    F         1.226   1.238   1.298   1.270   1.288   1.383   1.304   1.321   1.413
50    S         0.501   0.394   0.198   0.386   0.264   0.000   0.525   0.365   0.016
51    P         1.226   1.238   1.298   1.258   1.276   1.371   1.304   1.321   1.413
52    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    Q         1.226   1.238   1.298   1.193   1.214   1.312   1.304   1.321   1.413
57    Q        -1.647  -1.651  -1.554  -1.564  -1.604  -1.449  -1.368  -1.369  -1.210
58    D         0.145   0.093   0.085   0.128   0.044   0.026  -0.032  -0.127  -0.185
59    F        -0.505  -0.459  -0.575  -0.342  -0.262  -0.435  -0.588  -0.511  -0.668
60    M         0.145   0.215   0.125   0.242   0.339   0.198  -0.032   0.080  -0.114
61    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
62    S        -0.647  -0.582  -0.618  -0.975  -0.905  -0.875  -0.811  -0.749  -0.731
63    A        -0.046  -0.005   0.064  -0.307  -0.241  -0.155  -0.366  -0.299  -0.224
64    S        -0.107  -0.084   0.054  -0.584  -0.548  -0.309  -0.477  -0.444  -0.243
65    S         1.226   1.238   1.298   0.987   1.011   1.123   1.304   1.321   1.413
66    W         1.226   1.238   1.298   1.399   1.417   1.500   1.304   1.321   1.413
67    D         1.226   1.238   1.298   1.181   1.195   1.301   1.304   1.321   1.413
68    G        -0.773  -0.715  -0.642  -0.975  -0.885  -0.826  -0.922  -0.847  -0.756
69    K         1.226   1.238   1.298   1.199   1.215   1.317   1.304   1.321   1.413
70    V         0.501   0.394   0.198   0.564   0.429   0.135   0.525   0.365   0.016
71    R         1.226   1.238   1.298   1.276   1.296   1.388   1.304   1.321   1.413
72    I         1.226   1.238   1.298   1.213   1.240   1.330   1.304   1.321   1.413
73    W        -0.046   0.016   0.086  -0.000   0.098   0.182  -0.366  -0.261  -0.184
74    D        -0.046   0.016   0.086  -0.119  -0.007   0.064  -0.366  -0.261  -0.184
75    V        -0.647  -0.583  -0.608  -0.754  -0.669  -0.684  -0.811  -0.739  -0.718
76    -        -1.335  -1.366  -1.185  -1.405  -1.470  -1.216  -1.261  -1.288  -1.067
77    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
78    Q        -1.647  -1.718  -1.570  -1.544  -1.662  -1.485  -1.368  -1.412  -1.222
79    N        -1.314  -1.302  -1.163  -1.414  -1.369  -1.204  -1.256  -1.229  -1.047
80    G         1.226   1.238   1.298   1.139   1.158   1.262   1.304   1.321   1.413
81    V        -1.314  -1.195  -1.149  -1.365  -1.174  -1.152  -1.256  -1.122  -1.032
82    P        -1.314  -1.338  -1.171  -1.372  -1.429  -1.202  -1.256  -1.266  -1.054
83    Q        -0.838  -0.870  -1.085  -0.536  -0.582  -0.866  -0.700  -0.738  -0.964
84    G         1.226   1.238   1.298   1.139   1.158   1.262   1.304   1.321   1.413
85    R        -1.106  -1.214  -1.139  -0.938  -1.096  -1.023  -1.034  -1.136  -1.024
86    A         1.226   1.238   1.298   1.087   1.099   1.215   1.304   1.321   1.413
87    Q        -0.855  -0.849  -0.672  -0.831  -0.819  -0.573  -1.034  -1.023  -0.793
88    H        -0.838  -0.800  -1.071  -0.403  -0.371  -0.754  -0.700  -0.663  -0.949
89    E         0.145   0.137   0.093   0.225   0.208   0.078  -0.032  -0.051  -0.172
90    S         0.501   0.577   0.216   0.736   0.830   0.276   0.525   0.630   0.047
91    S        -1.647  -1.582  -1.537  -1.470  -1.379  -1.356  -1.368  -1.297  -1.194
92    S        -0.505  -0.436  -0.592  -0.635  -0.549  -0.800  -0.588  -0.507  -0.695
93    P         1.226   1.238   1.298   1.258   1.276   1.371   1.304   1.321   1.413
94    V         1.226   1.238   1.298   1.175   1.191   1.296   1.304   1.321   1.413
95    L        -0.046  -0.026   0.067  -0.122  -0.095   0.032  -0.366  -0.336  -0.219
96    C        -0.505  -0.400  -0.575  -0.596  -0.450  -0.665  -0.588  -0.444  -0.669
97    T        -1.439  -1.435  -1.531  -1.224  -1.209  -1.416  -1.145  -1.144  -1.188
98    R        -0.838  -1.015  -1.117  -0.477  -0.717  -0.892  -0.700  -0.902  -0.997
99    W         0.501   0.394   0.198   0.802   0.672   0.365   0.525   0.365   0.016
100   S         0.501   0.394   0.198   0.391   0.269   0.013   0.525   0.365   0.016
101   N        -1.647  -1.681  -1.554  -1.403  -1.449  -1.277  -1.368  -1.389  -1.210
102   D         1.226   1.238   1.298   1.181   1.195   1.301   1.304   1.321   1.413
103   G         1.226   1.238   1.298   1.139   1.158   1.262   1.304   1.321   1.413
104   T         0.501   0.573   0.217   0.541   0.632   0.130   0.525   0.625   0.049
105   K         0.501   0.573   0.217   0.604   0.688   0.228   0.525   0.625   0.049
106   V         0.145   0.232   0.111   0.083   0.214   0.003  -0.032   0.108  -0.139
107   A        -0.046  -0.026   0.067  -0.317  -0.290  -0.141  -0.366  -0.336  -0.219
108   S         1.226   1.238   1.298   0.987   1.011   1.123   1.304   1.321   1.413
109   G         0.501   0.394   0.198   0.517   0.379   0.075   0.525   0.365   0.016
110   G         0.501   0.461   0.205   0.503   0.454   0.050   0.525   0.465   0.028
111   C        -0.647  -0.663  -0.623  -0.634  -0.658  -0.607  -0.811  -0.819  -0.737
112   D         1.226   1.238   1.298   1.181   1.195   1.301   1.304   1.321   1.413
113   N        -0.046  -0.053   0.057  -0.193  -0.211  -0.059  -0.366  -0.386  -0.237
114   A        -1.647  -1.561  -1.529  -1.664  -1.550  -1.517  -1.368  -1.275  -1.187
115   L        -0.773  -0.773  -0.652  -0.892  -0.924  -0.737  -0.922  -0.926  -0.768
116   K         0.501   0.443   0.201   0.604   0.536   0.202   0.525   0.438   0.021
117   L        -0.647  -0.537  -0.600  -0.689  -0.537  -0.593  -0.811  -0.667  -0.707
118   Y        -0.505  -0.529  -0.581  -0.330  -0.349  -0.439  -0.588  -0.600  -0.675
119   D         1.226   1.238   1.298   1.181   1.195   1.301   1.304   1.321   1.413
120   I        -1.314  -1.320  -1.156  -1.223  -1.213  -0.976  -1.256  -1.250  -1.040
121   A        -0.505  -0.516  -0.605  -0.579  -0.621  -0.727  -0.588  -0.620  -0.711
122   S        -0.107  -0.083   0.055  -0.526  -0.476  -0.251  -0.477  -0.441  -0.241
123   G        -0.046  -0.010   0.069  -0.283  -0.223  -0.110  -0.366  -0.308  -0.214
124   Q         1.226   1.238   1.298   1.193   1.214   1.312   1.304   1.321   1.413
125   T        -1.314  -1.299  -1.159  -1.525  -1.507  -1.285  -1.256  -1.230  -1.044
126   Q         0.501   0.394   0.198   0.618   0.498   0.242   0.525   0.365   0.016
127   Q         1.226   1.238   1.298   1.193   1.214   1.312   1.304   1.321   1.413
128   I        -0.046  -0.076   0.054  -0.226  -0.292  -0.097  -0.366  -0.428  -0.244
129   G         0.145   0.067   0.088   0.007  -0.135  -0.133  -0.032  -0.170  -0.181
130   M        -1.188  -1.092  -1.125  -1.237  -1.129  -1.116  -1.145  -1.053  -1.012
131   H         1.226   1.238   1.298   1.371   1.388   1.475   1.304   1.321   1.413
132   S        -1.106  -1.058  -1.124  -1.017  -0.935  -1.058  -1.034  -0.972  -1.007
133   A        -1.314  -1.320  -1.160  -1.493  -1.471  -1.214  -1.256  -1.246  -1.044
134   P        -0.647  -0.675  -0.608  -0.819  -0.861  -0.750  -0.811  -0.832  -0.720
135   I         0.145   0.122   0.085   0.083   0.044  -0.043  -0.032  -0.076  -0.187
136   K        -0.647  -0.610  -0.611  -0.674  -0.630  -0.599  -0.811  -0.771  -0.724
137   V        -1.188  -1.063  -1.129  -1.195  -0.985  -1.096  -1.145  -1.021  -1.016
138   L        -0.046   0.016   0.086  -0.206  -0.109  -0.008  -0.366  -0.261  -0.184
139   R         1.226   1.238   1.298   1.276   1.296   1.388   1.304   1.321   1.413
140   F         0.145   0.123   0.093   0.216   0.179   0.111  -0.032  -0.074  -0.171
141   V         0.501   0.394   0.198   0.580   0.449   0.175   0.525   0.365   0.016
142   Q        -1.106  -1.068  -1.122  -0.953  -0.884  -1.058  -1.034  -0.977  -1.004
143   C        -0.046  -0.076   0.054  -0.115  -0.214  -0.032  -0.366  -0.428  -0.244
144   G        -0.188  -0.331  -0.554  -0.023  -0.198  -0.491  -0.143  -0.331  -0.639
145   P         0.145   0.067   0.088   0.140   0.001  -0.012  -0.032  -0.170  -0.181
146   S         0.145   0.151   0.092  -0.002   0.008  -0.157  -0.032  -0.026  -0.172
147   N         0.360   0.212   0.134   0.437   0.233   0.075   0.315   0.075  -0.098
148   T        -0.305  -0.377  -0.574  -0.240  -0.359  -0.695  -0.295  -0.398  -0.665
149   E        -0.855  -0.779  -0.652  -0.874  -0.761  -0.594  -1.034  -0.939  -0.769
150   C        -1.314  -1.338  -1.171  -1.122  -1.141  -0.927  -1.256  -1.266  -1.054
151   I        -1.188  -1.175  -1.127  -1.119  -1.106  -1.036  -1.145  -1.125  -1.014
152   V        -0.107  -0.085   0.054  -0.442  -0.420  -0.183  -0.477  -0.446  -0.243
153   T        -0.046  -0.010   0.069  -0.372  -0.303  -0.211  -0.366  -0.308  -0.214
154   G         0.501   0.443   0.201   0.517   0.445   0.080   0.525   0.438   0.021
155   S         0.145   0.059   0.080  -0.125  -0.265  -0.240  -0.032  -0.185  -0.195
156   W         1.226   1.238   1.298   1.399   1.417   1.500   1.304   1.321   1.413
157   D         1.226   1.238   1.298   1.181   1.195   1.301   1.304   1.321   1.413
158   K         1.226   1.238   1.298   1.199   1.215   1.317   1.304   1.321   1.413
159   T        -0.188  -0.347  -0.551  -0.042  -0.247  -0.564  -0.143  -0.352  -0.635
160   I        -0.647  -0.605  -0.616  -0.653  -0.599  -0.599  -0.811  -0.763  -0.729
161   K         0.501   0.443   0.201   0.618   0.552   0.237   0.525   0.438   0.021
162   Y         0.501   0.573   0.217   0.743   0.828   0.346   0.525   0.625   0.049
163   W         1.226   1.238   1.298   1.399   1.417   1.500   1.304   1.321   1.413
164   D         1.226   1.238   1.298   1.181   1.195   1.301   1.304   1.321   1.413
165   M        -1.188  -1.186  -1.130  -0.944  -0.947  -0.874  -1.145  -1.131  -1.016
166   R         1.226   1.238   1.298   1.276   1.296   1.388   1.304   1.321   1.413
167   Q        -1.188  -1.154  -1.130  -1.350  -1.306  -1.248  -1.145  -1.107  -1.016
168   P        -0.188  -0.331  -0.554   0.002  -0.200  -0.613  -0.143  -0.331  -0.639
169   Q        -0.505  -0.609  -0.622  -0.462  -0.623  -0.652  -0.588  -0.735  -0.733
170   P         1.226   1.238   1.298   1.258   1.276   1.371   1.304   1.321   1.413
171   V        -0.647  -0.705  -0.616  -0.754  -0.827  -0.698  -0.811  -0.861  -0.729
172   S        -1.106  -1.076  -1.127  -1.208  -1.202  -1.184  -1.034  -1.020  -1.012
173   T         1.226   1.238   1.298   1.163   1.184   1.284   1.304   1.321   1.413
174   V        -0.647  -0.596  -0.602  -0.715  -0.645  -0.612  -0.811  -0.748  -0.713
175   M        -1.773  -1.730  -1.562  -1.723  -1.687  -1.429  -1.479  -1.433  -1.217
176   M        -0.647  -0.686  -0.618  -0.553  -0.604  -0.524  -0.811  -0.832  -0.728
177   P         0.501   0.394   0.198   0.651   0.519   0.217   0.525   0.365   0.016
178   E         1.226   1.238   1.298   1.332   1.353   1.439   1.304   1.321   1.413
179   R         1.226   1.238   1.298   1.276   1.296   1.388   1.304   1.321   1.413
180   V         0.501   0.443   0.201   0.554   0.478   0.112   0.525   0.438   0.021
181   Y         1.226   1.238   1.298   1.339   1.357   1.446   1.304   1.321   1.413
182   S        -1.314  -1.306  -1.156  -1.424  -1.422  -1.183  -1.256  -1.237  -1.041
183   M         1.226   1.238   1.298   1.406   1.424   1.506   1.304   1.321   1.413
184   D         1.226   1.238   1.298   1.181   1.195   1.301   1.304   1.321   1.413
185   N        -1.980  -2.018  -1.888  -1.697  -1.757  -1.647  -1.479  -1.505  -1.328
186   K        -1.106  -1.163  -1.128  -1.184  -1.241  -1.172  -1.034  -1.076  -1.010
187   Q        -0.838  -1.015  -1.117  -0.564  -0.806  -0.965  -0.700  -0.902  -0.997
188   S        -1.647  -1.681  -1.554  -1.522  -1.565  -1.417  -1.368  -1.389  -1.210
189   L         1.226   1.238   1.298   1.276   1.292   1.388   1.304   1.321   1.413
190   L         0.501   0.548   0.213   0.699   0.753   0.333   0.525   0.590   0.041
191   V         0.501   0.461   0.205   0.564   0.515   0.146   0.525   0.465   0.028
192   V         1.226   1.238   1.298   1.175   1.191   1.296   1.304   1.321   1.413
193   A        -0.046  -0.045   0.056  -0.339  -0.353  -0.200  -0.366  -0.372  -0.238
194   T        -0.505  -0.385  -0.568  -0.385  -0.223  -0.433  -0.588  -0.422  -0.658
195   A         1.226   1.238   1.298   1.087   1.099   1.215   1.304   1.321   1.413
196   E         0.145   0.123   0.093   0.225   0.185   0.079  -0.032  -0.074  -0.171
197   R         1.226   1.238   1.298   1.276   1.296   1.388   1.304   1.321   1.413
198   H        -0.838  -0.894  -1.092  -0.389  -0.468  -0.794  -0.700  -0.770  -0.971
199   I         1.226   1.238   1.298   1.213   1.240   1.330   1.304   1.321   1.413
200   A        -1.647  -1.718  -1.570  -1.612  -1.674  -1.434  -1.368  -1.412  -1.222
201   I        -0.647  -0.687  -0.620  -0.746  -0.806  -0.704  -0.811  -0.850  -0.734
202   I         1.226   1.238   1.298   1.213   1.240   1.330   1.304   1.321   1.413
203   N        -0.046   0.025   0.081  -0.203  -0.073  -0.020  -0.366  -0.245  -0.193
204   L         1.226   1.238   1.298   1.276   1.292   1.388   1.304   1.321   1.413
205   A        -1.314  -1.344  -1.167  -1.453  -1.509  -1.255  -1.256  -1.272  -1.051
206   N        -0.188  -0.331  -0.554   0.052  -0.126  -0.464  -0.143  -0.331  -0.639
207   P         1.226   1.238   1.298   1.258   1.276   1.371   1.304   1.321   1.413
208   T        -0.855  -0.789  -0.648  -1.070  -0.973  -0.760  -1.034  -0.953  -0.764
209   T        -1.314  -1.325  -1.169  -1.366  -1.388  -1.170  -1.256  -1.257  -1.052
210   I        -0.188  -0.347  -0.551   0.018  -0.180  -0.503  -0.143  -0.352  -0.635
211   F        -0.188  -0.347  -0.551   0.072  -0.136  -0.464  -0.143  -0.352  -0.635
212   K         1.226   1.238   1.298   1.199   1.215   1.317   1.304   1.321   1.413
213   A        -1.647  -1.535  -1.530  -1.637  -1.450  -1.469  -1.368  -1.255  -1.190
214   T        -1.439  -1.541  -1.538  -1.324  -1.452  -1.431  -1.145  -1.245  -1.194
215   T        -1.106  -1.008  -1.106  -0.902  -0.776  -0.899  -1.034  -0.927  -0.991
216   S         1.226   1.238   1.298   0.987   1.011   1.123   1.304   1.321   1.413
217   P         0.501   0.443   0.201   0.623   0.549   0.148   0.525   0.438   0.021
218   L         1.226   1.238   1.298   1.276   1.292   1.388   1.304   1.321   1.413
219   K         1.226   1.238   1.298   1.199   1.215   1.317   1.304   1.321   1.413
220   W         0.145   0.093   0.085   0.316   0.227   0.160  -0.032  -0.127  -0.185
221   Q         1.226   1.238   1.298   1.193   1.214   1.312   1.304   1.321   1.413
222   T         1.226   1.238   1.298   1.163   1.184   1.284   1.304   1.321   1.413
223   R         1.226   1.238   1.298   1.276   1.296   1.388   1.304   1.321   1.413
224   C        -0.855  -0.796  -0.664  -1.071  -0.990  -0.766  -1.034  -0.961  -0.784
225   V        -0.505  -0.476  -0.585  -0.466  -0.409  -0.579  -0.588  -0.535  -0.685
226   A        -0.046  -0.012   0.070  -0.477  -0.421  -0.288  -0.366  -0.311  -0.214
227   C         1.226   1.238   1.298   1.390   1.409   1.492   1.304   1.321   1.413
228   Y        -0.505  -0.617  -0.621  -0.269  -0.439  -0.444  -0.588  -0.741  -0.731
229   N        -0.647  -0.655  -0.620  -0.650  -0.643  -0.590  -0.811  -0.806  -0.732
230   E        -1.647  -1.718  -1.570  -1.415  -1.527  -1.367  -1.368  -1.412  -1.222
231   A        -0.505  -0.526  -0.589  -0.605  -0.624  -0.781  -0.588  -0.595  -0.691
232   D        -0.647  -0.680  -0.614  -0.713  -0.737  -0.638  -0.811  -0.824  -0.724
233   G         1.226   1.238   1.298   1.139   1.158   1.262   1.304   1.321   1.413
234   Y        -0.046  -0.012   0.070  -0.090  -0.039   0.072  -0.366  -0.311  -0.214
235   A         1.226   1.238   1.298   1.087   1.099   1.215   1.304   1.321   1.413
236   I        -0.046  -0.010   0.069  -0.226  -0.161  -0.064  -0.366  -0.308  -0.214
237   G         1.226   1.238   1.298   1.139   1.158   1.262   1.304   1.321   1.413
238   S         1.226   1.238   1.298   0.987   1.011   1.123   1.304   1.321   1.413
239   V        -0.046  -0.012   0.070  -0.226  -0.165  -0.064  -0.366  -0.311  -0.214
240   E         1.226   1.238   1.298   1.332   1.353   1.439   1.304   1.321   1.413
241   G         1.226   1.238   1.298   1.139   1.158   1.262   1.304   1.321   1.413
242   R         1.226   1.238   1.298   1.276   1.296   1.388   1.304   1.321   1.413
243   C         1.226   1.238   1.298   1.390   1.409   1.492   1.304   1.321   1.413
244   S        -0.188  -0.183  -0.529  -0.162  -0.162  -0.690  -0.143  -0.140  -0.605
245   I         0.501   0.548   0.213   0.604   0.670   0.197   0.525   0.590   0.041
246   R        -0.188  -0.062  -0.517   0.003   0.159  -0.455  -0.143   0.019  -0.589
247   Y         0.501   0.461   0.205   0.738   0.693   0.314   0.525   0.465   0.028
248   I        -0.046  -0.060   0.055  -0.226  -0.260  -0.094  -0.366  -0.400  -0.241
249   D        -0.188  -0.225  -0.531  -0.006  -0.055  -0.479  -0.143  -0.199  -0.608
250   D        -0.107  -0.083   0.054  -0.259  -0.230  -0.017  -0.477  -0.441  -0.243
251   G        -2.439  -2.311  -2.181  -2.174  -1.981  -1.855  -1.702  -1.601  -1.419
252   M        -1.980  -2.016  -1.892  -1.524  -1.606  -1.477  -1.479  -1.504  -1.330
253   Q        -0.505  -0.635  -0.622  -0.551  -0.773  -0.804  -0.588  -0.756  -0.732
254   K        -1.106  -1.137  -1.126  -1.105  -1.163  -1.168  -1.034  -1.060  -1.011
255   K        -0.838  -1.015  -1.117  -0.624  -0.887  -1.093  -0.700  -0.902  -0.997
256   S        -1.331  -1.347  -1.183  -1.428  -1.444  -1.201  -1.269  -1.276  -1.065
257   G        -0.046  -0.076   0.054  -0.259  -0.311  -0.108  -0.366  -0.428  -0.244
258   F         1.226   1.238   1.298   1.270   1.288   1.383   1.304   1.321   1.413
259   S         1.226   1.238   1.298   0.987   1.011   1.123   1.304   1.321   1.413
260   F         1.226   1.238   1.298   1.270   1.288   1.383   1.304   1.321   1.413
261   K         0.145   0.173   0.100   0.126   0.166   0.034  -0.032   0.011  -0.159
262   C         1.226   1.238   1.298   1.390   1.409   1.492   1.304   1.321   1.413
263   H         1.226   1.238   1.298   1.371   1.388   1.475   1.304   1.321   1.413
264   R         1.226   1.238   1.298   1.276   1.296   1.388   1.304   1.321   1.413
265   Q        -1.106  -1.152  -1.134  -1.001  -1.050  -1.047  -1.034  -1.063  -1.016
266   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
267   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
268   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
269   T        -1.647  -1.688  -1.552  -1.596  -1.662  -1.495  -1.368  -1.396  -1.208
270   N        -2.106  -2.076  -1.894  -2.038  -2.013  -1.766  -1.590  -1.555  -1.332
271   P        -1.647  -1.564  -1.540  -1.537  -1.423  -1.404  -1.368  -1.281  -1.197
272   N         1.226   1.238   1.298   1.237   1.262   1.352   1.304   1.321   1.413
273   R        -0.802  -0.783  -0.668  -0.906  -0.881  -0.711  -0.976  -0.949  -0.788
274   A        -0.802  -0.783  -0.668  -1.025  -0.997  -0.826  -0.976  -0.949  -0.788
275   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
276   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
277   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
278   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
279   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
280   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
281   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
282   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
283   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
284   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
285   G        -0.802  -0.775  -0.659  -1.101  -1.061  -0.901  -0.976  -0.940  -0.777
286   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
287   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
288   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
289   S        -0.068  -0.034   0.066  -0.429  -0.367  -0.227  -0.406  -0.352  -0.220
290   N        -0.601  -0.578  -0.624  -0.801  -0.770  -0.833  -0.691  -0.661  -0.731
291   G        -1.335  -1.301  -1.168  -1.585  -1.537  -1.331  -1.261  -1.219  -1.050
292   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
293   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
294   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
295   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
296   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
297   Q        -1.106  -1.163  -1.128  -0.937  -1.011  -1.042  -1.034  -1.076  -1.010
298   S        -1.106  -1.215  -1.144  -1.245  -1.400  -1.284  -1.034  -1.140  -1.029
299   L        -1.773  -1.755  -1.574  -1.572  -1.582  -1.334  -1.479  -1.449  -1.225
300   V        -0.505  -0.432  -0.596  -0.502  -0.407  -0.663  -0.588  -0.502  -0.699
301   Y         0.501   0.394   0.198   0.757   0.632   0.351   0.525   0.365   0.016
302   P        -0.855  -0.857  -0.673  -1.157  -1.177  -0.894  -1.034  -1.032  -0.795
303   V         1.226   1.238   1.298   1.175   1.191   1.296   1.304   1.321   1.413
304   N         1.226   1.238   1.298   1.237   1.262   1.352   1.304   1.321   1.413
305   S        -0.505  -0.590  -0.602  -0.716  -0.833  -0.850  -0.588  -0.689  -0.708
306   I         1.226   1.238   1.298   1.213   1.240   1.330   1.304   1.321   1.413
307   A        -0.647  -0.618  -0.612  -0.953  -0.938  -0.866  -0.811  -0.784  -0.725
308   F         1.226   1.238   1.298   1.270   1.288   1.383   1.304   1.321   1.413
309   H         1.226   1.238   1.298   1.371   1.388   1.475   1.304   1.321   1.413
310   P         1.226   1.238   1.298   1.258   1.276   1.371   1.304   1.321   1.413
311   L        -1.188  -1.063  -1.129  -1.133  -0.972  -1.026  -1.145  -1.021  -1.016
312   Y        -0.505  -0.586  -0.609  -0.244  -0.358  -0.401  -0.588  -0.695  -0.718
313   G         1.226   1.238   1.298   1.139   1.158   1.262   1.304   1.321   1.413
314   T         1.226   1.238   1.298   1.163   1.184   1.284   1.304   1.321   1.413
315   F         1.226   1.238   1.298   1.270   1.288   1.383   1.304   1.321   1.413
316   V        -1.106  -1.068  -1.122  -1.188  -1.113  -1.164  -1.034  -0.977  -1.004
317   T         1.226   1.238   1.298   1.163   1.184   1.284   1.304   1.321   1.413
318   A         1.226   1.238   1.298   1.087   1.099   1.215   1.304   1.321   1.413
319   G         1.226   1.238   1.298   1.139   1.158   1.262   1.304   1.321   1.413
320   G        -0.647  -0.651  -0.617  -0.960  -0.951  -0.880  -0.811  -0.794  -0.726
321   D         1.226   1.238   1.298   1.181   1.195   1.301   1.304   1.321   1.413
322   G         1.226   1.238   1.298   1.139   1.158   1.262   1.304   1.321   1.413
323   T        -0.046  -0.025   0.066  -0.372  -0.335  -0.219  -0.366  -0.335  -0.220
324   F         0.501   0.443   0.201   0.675   0.607   0.263   0.525   0.438   0.021
325   N        -1.647  -1.621  -1.544  -1.299  -1.273  -1.229  -1.368  -1.329  -1.200
326   F         1.226   1.238   1.298   1.270   1.288   1.383   1.304   1.321   1.413
327   W         1.226   1.238   1.298   1.399   1.417   1.500   1.304   1.321   1.413
328   D         1.226   1.238   1.298   1.181   1.195   1.301   1.304   1.321   1.413
329   K         1.226   1.238   1.298   1.199   1.215   1.317   1.304   1.321   1.413
330   N        -0.046   0.016   0.086  -0.223  -0.119  -0.024  -0.366  -0.261  -0.184
331   Q        -1.314  -1.265  -1.162  -1.469  -1.429  -1.218  -1.256  -1.205  -1.046
332   R        -0.647  -0.663  -0.623  -0.622  -0.634  -0.547  -0.811  -0.819  -0.737
333   H        -0.046  -0.004   0.072  -0.078  -0.006   0.070  -0.366  -0.298  -0.210
334   R         1.226   1.238   1.298   1.276   1.296   1.388   1.304   1.321   1.413
335   L         1.226   1.238   1.298   1.276   1.292   1.388   1.304   1.321   1.413
336   K         1.226   1.238   1.298   1.199   1.215   1.317   1.304   1.321   1.413
337   G        -0.505  -0.415  -0.592  -0.609  -0.490  -0.777  -0.588  -0.483  -0.695
338   Y        -0.107  -0.073   0.061  -0.190  -0.131   0.066  -0.477  -0.423  -0.230
339   P         1.226   1.238   1.298   1.258   1.276   1.371   1.304   1.321   1.413
340   T        -2.439  -2.311  -2.181  -2.179  -1.973  -1.870  -1.702  -1.601  -1.419
341   L        -0.647  -0.598  -0.611  -0.629  -0.590  -0.536  -0.811  -0.763  -0.724
342   Q        -1.314  -1.185  -1.152  -1.329  -1.145  -1.081  -1.256  -1.116  -1.035
343   A        -1.106  -1.016  -1.108  -0.959  -0.846  -0.949  -1.034  -0.937  -0.993
344   S        -0.647  -0.587  -0.615  -0.945  -0.866  -0.855  -0.811  -0.749  -0.728
345   I         1.226   1.238   1.298   1.213   1.240   1.330   1.304   1.321   1.413
346   P        -0.505  -0.582  -0.607  -0.493  -0.601  -0.714  -0.588  -0.677  -0.714
347   V        -1.188  -1.254  -1.151  -1.255  -1.349  -1.169  -1.145  -1.191  -1.035
348   C        -0.647  -0.638  -0.613  -0.673  -0.657  -0.640  -0.811  -0.781  -0.722
349   S        -2.106  -1.978  -1.893  -1.979  -1.817  -1.681  -1.590  -1.488  -1.332
350   F         1.226   1.238   1.298   1.270   1.288   1.383   1.304   1.321   1.413
351   N         1.226   1.238   1.298   1.237   1.262   1.352   1.304   1.321   1.413
352   R        -0.046  -0.026   0.067  -0.159  -0.129  -0.009  -0.366  -0.336  -0.219
353   N        -0.647  -0.640  -0.604  -0.730  -0.696  -0.641  -0.811  -0.777  -0.712
354   G         1.226   1.238   1.298   1.139   1.158   1.262   1.304   1.321   1.413
355   S        -0.505  -0.459  -0.575  -0.685  -0.599  -0.765  -0.588  -0.511  -0.668
356   V         0.145   0.215   0.125   0.108   0.222   0.042  -0.032   0.080  -0.114
357   F         0.501   0.573   0.217   0.675   0.759   0.289   0.525   0.625   0.049
358   A         1.226   1.238   1.298   1.087   1.099   1.215   1.304   1.321   1.413
359   Y         1.226   1.238   1.298   1.339   1.357   1.446   1.304   1.321   1.413
360   A         1.226   1.238   1.298   1.087   1.099   1.215   1.304   1.321   1.413
361   L        -1.647  -1.556  -1.540  -1.385  -1.268  -1.236  -1.368  -1.276  -1.197
362   S         1.226   1.238   1.298   0.987   1.011   1.123   1.304   1.321   1.413
363   Y         1.226   1.238   1.298   1.339   1.357   1.446   1.304   1.321   1.413
364   D         1.226   1.238   1.298   1.181   1.195   1.301   1.304   1.321   1.413
365   W         1.226   1.238   1.298   1.399   1.417   1.500   1.304   1.321   1.413
366   H        -0.046   0.016   0.086  -0.318  -0.225  -0.100  -0.366  -0.261  -0.184
367   Q        -0.647  -0.600  -0.621  -0.709  -0.667  -0.633  -0.811  -0.770  -0.734
368   G         1.226   1.238   1.298   1.139   1.158   1.262   1.304   1.321   1.413
369   H        -0.046  -0.056   0.056  -0.004  -0.031   0.120  -0.366  -0.391  -0.239
370   M        -1.647  -1.698  -1.553  -1.390  -1.488  -1.338  -1.368  -1.401  -1.209
371   G        -0.188  -0.287  -0.548  -0.028  -0.148  -0.495  -0.143  -0.272  -0.631
372   N         1.226   1.238   1.298   1.237   1.262   1.352   1.304   1.321   1.413
373   R        -1.106  -1.147  -1.138  -0.961  -1.054  -1.067  -1.034  -1.086  -1.023
374   P        -0.838  -0.870  -1.085  -0.554  -0.609  -0.969  -0.700  -0.738  -0.964
375   D        -0.188  -0.331  -0.554  -0.030  -0.222  -0.568  -0.143  -0.331  -0.639
376   Y        -0.188  -0.287  -0.548   0.149   0.024  -0.383  -0.143  -0.272  -0.631
377   P         1.226   1.238   1.298   1.258   1.276   1.371   1.304   1.321   1.413
378   N        -0.188  -0.347  -0.551   0.056  -0.141  -0.451  -0.143  -0.352  -0.635
379   V        -1.647  -1.602  -1.563  -1.515  -1.478  -1.408  -1.368  -1.332  -1.217
380   I         0.145   0.059   0.080   0.108  -0.034  -0.043  -0.032  -0.185  -0.195
381   R        -0.773  -0.753  -0.650  -0.703  -0.668  -0.539  -0.922  -0.902  -0.766
382   L         0.501   0.443   0.201   0.680   0.611   0.265   0.525   0.438   0.021
383   H         1.226   1.238   1.298   1.371   1.388   1.475   1.304   1.321   1.413
384   A        -0.647  -0.686  -0.620  -0.776  -0.821  -0.689  -0.811  -0.849  -0.733
385   T         0.145   0.067   0.088   0.059  -0.073  -0.068  -0.032  -0.170  -0.181
386   T        -1.188  -1.254  -1.151  -1.166  -1.242  -1.080  -1.145  -1.191  -1.035
387   D        -0.505  -0.617  -0.621  -0.504  -0.692  -0.713  -0.588  -0.741  -0.731
388   E        -0.505  -0.510  -0.605  -0.331  -0.382  -0.512  -0.588  -0.625  -0.711
389   E         1.226   1.238   1.298   1.332   1.353   1.439   1.304   1.321   1.413
390   V        -0.647  -0.697  -0.624  -0.691  -0.728  -0.597  -0.811  -0.850  -0.737
391   K         1.226   1.238   1.298   1.199   1.215   1.317   1.304   1.321   1.413
392   E        -1.439  -1.390  -1.185  -1.444  -1.384  -1.098  -1.368  -1.313  -1.067
393   K         0.145   0.067   0.088   0.126  -0.000   0.014  -0.032  -0.170  -0.181
394   K        -0.647  -0.600  -0.621  -0.676  -0.627  -0.606  -0.811  -0.770  -0.734
395   K         0.501   0.394   0.198   0.563   0.420   0.091   0.525   0.365   0.016
396   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
397   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
398   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
399   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
400   -        -1.335  -1.323  -1.162  -1.355  -1.341  -1.116  -1.261  -1.244  -1.044
401   R         1.226   1.238   1.298   1.276   1.296   1.388   1.304   1.321   1.413
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P40066
Output conservation file - output/P40066
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
