1     M         1.833   1.843   1.858   2.180   2.192   2.220   1.976   1.987   2.007
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    S        -0.068  -0.063  -0.046  -0.108  -0.093  -0.072  -0.264  -0.256  -0.229
35    A        -0.068  -0.063  -0.046   0.100   0.108   0.137  -0.264  -0.256  -0.229
36    C        -0.068  -0.063  -0.046   0.223   0.231   0.259  -0.264  -0.256  -0.229
37    P        -1.180  -1.171  -1.160  -0.911  -0.879  -0.876  -1.011  -0.996  -0.975
38    C         0.088   0.035   0.034   0.185   0.117   0.120  -0.015  -0.097  -0.100
39    N        -1.180  -1.171  -1.160  -1.253  -1.224  -1.219  -1.011  -0.996  -0.975
40    I        -1.180  -1.171  -1.160  -1.318  -1.308  -1.284  -1.011  -0.996  -0.975
41    V         0.088   0.035   0.034  -0.117  -0.197  -0.193  -0.015  -0.097  -0.100
42    I        -1.180  -1.171  -1.160  -1.051  -1.052  -1.016  -1.011  -0.996  -0.975
43    L         1.833   1.843   1.858   1.614   1.632   1.653   1.976   1.987   2.007
44    P        -1.180  -1.171  -1.160  -1.106  -1.066  -1.071  -1.011  -0.996  -0.975
45    V        -1.180  -1.171  -1.160  -0.975  -0.971  -0.940  -1.011  -0.996  -0.975
46    E        -1.180  -1.171  -1.160  -1.271  -1.253  -1.237  -1.011  -0.996  -0.975
47    I         0.088   0.035   0.034   0.416   0.310   0.299  -0.015  -0.097  -0.100
48    L        -1.180  -1.171  -1.160  -1.283  -1.286  -1.248  -1.011  -0.996  -0.975
49    K        -1.180  -1.171  -1.160  -1.117  -1.115  -1.082  -1.011  -0.996  -0.975
50    N         0.088   0.035   0.034  -0.031  -0.115  -0.113  -0.015  -0.097  -0.100
51    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    S        -1.180  -1.171  -1.160  -1.179  -1.169  -1.144  -1.011  -0.996  -0.975
53    S         1.833   1.843   1.858   1.808   1.820   1.847   1.976   1.987   2.007
54    K        -1.180  -1.171  -1.160  -1.242  -1.238  -1.208  -1.011  -0.996  -0.975
55    D        -1.180  -1.171  -1.160  -1.248  -1.233  -1.213  -1.011  -0.996  -0.975
56    T        -1.180  -1.171  -1.160  -0.969  -0.956  -0.935  -1.011  -0.996  -0.975
57    K        -1.180  -1.171  -1.160  -1.162  -1.154  -1.127  -1.011  -0.996  -0.975
58    Y         0.088   0.035   0.034   0.099   0.017   0.019  -0.015  -0.097  -0.100
59    -         1.833   1.843   1.858   1.770   1.794   1.809   1.976   1.987   2.007
60    S        -1.180  -1.171  -1.160  -1.236  -1.225  -1.202  -1.011  -0.996  -0.975
61    L         1.833   1.843   1.858   1.614   1.632   1.653   1.976   1.987   2.007
62    Y        -1.180  -1.171  -1.160  -1.100  -1.081  -1.066  -1.011  -0.996  -0.975
63    T        -1.180  -1.171  -1.160  -1.040  -1.023  -1.005  -1.011  -0.996  -0.975
64    T         0.088   0.035   0.034  -0.117  -0.194  -0.193  -0.015  -0.097  -0.100
65    I         1.833   1.843   1.858   1.763   1.776   1.801   1.976   1.987   2.007
66    N         1.833   1.843   1.858   1.926   1.939   1.965   1.976   1.987   2.007
67    R        -1.180  -1.171  -1.160  -1.018  -0.984  -0.983  -1.011  -0.996  -0.975
68    G        -1.180  -1.171  -1.160  -0.969  -0.951  -0.935  -1.011  -0.996  -0.975
69    Y         1.833   1.843   1.858   2.006   2.014   2.045   1.976   1.987   2.007
70    D        -1.180  -1.171  -1.160  -1.179  -1.169  -1.144  -1.011  -0.996  -0.975
71    V         0.088   0.035   0.034  -0.022  -0.109  -0.103  -0.015  -0.097  -0.100
72    P         0.088   0.127   0.062   0.396   0.467   0.355  -0.015   0.047  -0.055
73    R         1.833   1.843   1.858   2.041   2.066   2.080   1.976   1.987   2.007
74    L         0.088   0.035   0.034   0.095  -0.017  -0.023  -0.015  -0.097  -0.100
75    K         0.088   0.127   0.061   0.024   0.085  -0.010  -0.015   0.047  -0.057
76    Y         0.088   0.035   0.034   0.099   0.017   0.019  -0.015  -0.097  -0.100
77    G         0.088   0.127   0.062   0.206   0.269   0.156  -0.015   0.047  -0.055
78    I         1.833   1.843   1.858   1.763   1.776   1.801   1.976   1.987   2.007
79    I         1.833   1.843   1.858   1.763   1.776   1.801   1.976   1.987   2.007
80    V        -1.180  -1.171  -1.160  -0.869  -0.868  -0.834  -1.011  -0.996  -0.975
81    S         0.088   0.127   0.062   0.062   0.120   0.023  -0.015   0.047  -0.055
82    P         0.088   0.127   0.062   0.450   0.516   0.414  -0.015   0.047  -0.055
83    R         1.833   1.843   1.858   2.041   2.066   2.080   1.976   1.987   2.007
84    V         0.088   0.035   0.034   0.020  -0.068  -0.063  -0.015  -0.097  -0.100
85    H         0.088   0.035   0.034   0.054  -0.017  -0.014  -0.015  -0.097  -0.100
86    S        -1.180  -1.171  -1.160  -1.179  -1.169  -1.144  -1.011  -0.996  -0.975
87    L        -1.180  -1.171  -1.160  -1.095  -1.100  -1.060  -1.011  -0.996  -0.975
88    E        -1.180  -1.171  -1.160  -1.184  -1.172  -1.150  -1.011  -0.996  -0.975
89    T         1.833   1.843   1.858   1.943   1.955   1.983   1.976   1.987   2.007
90    L        -1.180  -1.171  -1.160  -1.283  -1.286  -1.248  -1.011  -0.996  -0.975
91    F         0.088   0.035   0.034  -0.178  -0.260  -0.265  -0.015  -0.097  -0.100
92    S         0.088   0.127   0.062  -0.014   0.054  -0.061  -0.015   0.047  -0.055
93    D         1.833   1.843   1.858   1.808   1.823   1.847   1.976   1.987   2.007
94    L         0.088   0.127   0.062  -0.178  -0.111  -0.219  -0.015   0.047  -0.055
95    G        -1.180  -1.171  -1.160  -0.969  -0.951  -0.935  -1.011  -0.996  -0.975
96    F         0.088   0.035   0.034  -0.039  -0.129  -0.132  -0.015  -0.097  -0.100
97    D         1.833   1.843   1.858   1.808   1.823   1.847   1.976   1.987   2.007
98    K        -1.180  -1.171  -1.160  -1.089  -1.089  -1.055  -1.011  -0.996  -0.975
99    N         0.088   0.127   0.061   0.198   0.256   0.157  -0.015   0.047  -0.057
100   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
101   E        -1.180  -1.171  -1.160  -1.330  -1.309  -1.296  -1.011  -0.996  -0.975
102   K        -1.180  -1.171  -1.160  -1.179  -1.166  -1.144  -1.011  -0.996  -0.975
103   S        -1.180  -1.171  -1.160  -1.277  -1.261  -1.242  -1.011  -0.996  -0.975
104   S         0.088   0.035   0.034   0.349   0.247   0.240  -0.015  -0.097  -0.100
105   L        -1.180  -1.171  -1.160  -1.402  -1.395  -1.368  -1.011  -0.996  -0.975
106   Y         0.088   0.127   0.062   0.185   0.248   0.136  -0.015   0.047  -0.055
107   L         0.088   0.127   0.062  -0.204  -0.137  -0.248  -0.015   0.047  -0.055
108   L         1.833   1.843   1.858   1.614   1.632   1.653   1.976   1.987   2.007
109   L         1.833   1.843   1.858   1.614   1.632   1.653   1.976   1.987   2.007
110   N         0.088   0.035   0.034   0.258   0.162   0.163  -0.015  -0.097  -0.100
111   D        -1.180  -1.171  -1.160  -1.312  -1.296  -1.278  -1.011  -0.996  -0.975
112   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
113   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
114   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
115   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
116   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
117   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
118   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
119   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
120   H        -1.180  -1.171  -1.160  -0.869  -0.840  -0.834  -1.011  -0.996  -0.975
121   E         0.088   0.127   0.062  -0.027   0.045  -0.072  -0.015   0.047  -0.055
122   H        -1.180  -1.171  -1.160  -1.242  -1.194  -1.208  -1.011  -0.996  -0.975
123   F         1.833   1.843   1.858   1.817   1.833   1.856   1.976   1.987   2.007
124   E         0.088   0.035   0.034  -0.014  -0.103  -0.111  -0.015  -0.097  -0.100
125   Q        -1.180  -1.171  -1.160  -1.084  -1.045  -1.049  -1.011  -0.996  -0.975
126   L         0.088   0.127   0.062  -0.204  -0.137  -0.248  -0.015   0.047  -0.055
127   K        -1.180  -1.171  -1.160  -1.018  -1.015  -0.983  -1.011  -0.996  -0.975
128   G        -1.180  -1.171  -1.160  -1.156  -1.127  -1.122  -1.011  -0.996  -0.975
129   E         1.833   1.843   1.858   1.781   1.803   1.820   1.976   1.987   2.007
130   T        -1.180  -1.171  -1.160  -1.029  -1.017  -0.994  -1.011  -0.996  -0.975
131   N         0.088   0.127   0.061   0.198   0.256   0.157  -0.015   0.047  -0.057
132   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
133   -        -0.068  -0.063  -0.046  -0.310  -0.288  -0.274  -0.264  -0.256  -0.229
134   K         0.088   0.035   0.034   0.173   0.079   0.062  -0.015  -0.097  -0.100
135   D         1.833   1.843   1.858   1.808   1.823   1.847   1.976   1.987   2.007
136   L         0.088   0.127   0.062  -0.178  -0.111  -0.219  -0.015   0.047  -0.055
137   S         0.088   0.127   0.061   0.062   0.120   0.021  -0.015   0.047  -0.057
138   L        -1.180  -1.171  -1.160  -1.469  -1.461  -1.435  -1.011  -0.996  -0.975
139   P         0.088   0.127   0.061   0.353   0.422   0.305  -0.015   0.047  -0.057
140   T        -1.180  -1.171  -1.160  -0.953  -0.941  -0.919  -1.011  -0.996  -0.975
141   Y        -1.180  -1.171  -1.160  -0.906  -0.890  -0.871  -1.011  -0.996  -0.975
142   Y        -1.180  -1.171  -1.160  -0.975  -0.962  -0.940  -1.011  -0.996  -0.975
143   -        -0.068  -0.063  -0.046  -0.447  -0.444  -0.411  -0.264  -0.256  -0.229
144   -        -0.068  -0.063  -0.046  -0.248  -0.235  -0.212  -0.264  -0.256  -0.229
145   -        -0.068  -0.063  -0.046  -0.040  -0.026  -0.004  -0.264  -0.256  -0.229
146   -        -0.068  -0.063  -0.046  -0.134  -0.129  -0.098  -0.264  -0.256  -0.229
147   -        -0.068  -0.063  -0.046  -0.134  -0.129  -0.098  -0.264  -0.256  -0.229
148   -         1.833   1.843   1.858   1.996   2.010   2.035   1.976   1.987   2.007
149   -        -0.068  -0.063  -0.046   0.052   0.058   0.088  -0.264  -0.256  -0.229
150   -         1.833   1.843   1.858   1.770   1.782   1.809   1.976   1.987   2.007
151   I         1.833   1.843   1.858   1.763   1.776   1.801   1.976   1.987   2.007
152   P         1.833   1.843   1.858   2.128   2.149   2.168   1.976   1.987   2.007
153   K         0.088   0.035   0.034  -0.069  -0.160  -0.171  -0.015  -0.097  -0.100
154   V        -1.180  -1.171  -1.160  -1.078  -1.060  -1.043  -1.011  -0.996  -0.975
155   Q         0.088   0.035   0.034   0.341   0.259   0.266  -0.015  -0.097  -0.100
156   F         0.088   0.035   0.034   0.185   0.084   0.083  -0.015  -0.097  -0.100
157   L        -1.180  -1.171  -1.160  -1.378  -1.374  -1.343  -1.011  -0.996  -0.975
158   T        -1.180  -1.171  -1.160  -1.318  -1.286  -1.284  -1.011  -0.996  -0.975
159   E        -1.180  -1.171  -1.160  -1.390  -1.362  -1.356  -1.011  -0.996  -0.975
160   A        -1.180  -1.171  -1.160  -0.900  -0.883  -0.866  -1.011  -0.996  -0.975
161   F         0.088   0.127   0.061  -0.082  -0.008  -0.139  -0.015   0.047  -0.057
162   D         0.088   0.127   0.061  -0.014   0.056  -0.063  -0.015   0.047  -0.057
163   S        -1.180  -1.171  -1.160  -1.179  -1.169  -1.144  -1.011  -0.996  -0.975
164   -        -0.068  -0.063  -0.046  -0.239  -0.235  -0.203  -0.264  -0.256  -0.229
165   -        -0.068  -0.063  -0.046  -0.230  -0.226  -0.194  -0.264  -0.256  -0.229
166   -        -0.068  -0.063  -0.046  -0.195  -0.181  -0.159  -0.264  -0.256  -0.229
167   -        -0.068  -0.063  -0.046  -0.212  -0.208  -0.177  -0.264  -0.256  -0.229
168   -        -0.068  -0.063  -0.046  -0.310  -0.288  -0.274  -0.264  -0.256  -0.229
169   -         1.833   1.843   1.858   1.709   1.721   1.748   1.976   1.987   2.007
170   -        -0.068  -0.063  -0.046  -0.195  -0.181  -0.159  -0.264  -0.256  -0.229
171   -        -0.068  -0.063  -0.046  -0.346  -0.334  -0.310  -0.264  -0.256  -0.229
172   -        -0.068  -0.063  -0.046   0.010   0.017   0.046  -0.264  -0.256  -0.229
173   -         1.833   1.843   1.858   1.770   1.782   1.809   1.976   1.987   2.007
174   -        -0.068  -0.063  -0.046  -0.015  -0.009   0.021  -0.264  -0.256  -0.229
175   -        -0.068  -0.063  -0.046  -0.248  -0.243  -0.212  -0.264  -0.256  -0.229
176   -        -0.068  -0.063  -0.046  -0.134  -0.129  -0.098  -0.264  -0.256  -0.229
177   -        -0.068  -0.063  -0.046  -0.151  -0.138  -0.115  -0.264  -0.256  -0.229
178   -        -0.068  -0.063  -0.046  -0.447  -0.444  -0.411  -0.264  -0.256  -0.229
179   -        -0.068  -0.063  -0.046  -0.319  -0.315  -0.283  -0.264  -0.256  -0.229
180   -         1.833   1.843   1.858   1.770   1.782   1.809   1.976   1.987   2.007
181   -        -0.068  -0.063  -0.046  -0.195  -0.181  -0.159  -0.264  -0.256  -0.229
182   -        -0.068  -0.063  -0.046  -0.195  -0.190  -0.159  -0.264  -0.256  -0.229
183   -         1.833   1.843   1.858   1.636   1.646   1.674   1.976   1.987   2.007
184   E        -1.180  -1.171  -1.160  -1.253  -1.237  -1.219  -1.011  -0.996  -0.975
185   H         0.088   0.035   0.034   0.345   0.275   0.264  -0.015  -0.097  -0.100
186   T        -1.180  -1.171  -1.160  -0.854  -0.852  -0.819  -1.011  -0.996  -0.975
187   L         0.088   0.127   0.061  -0.204  -0.137  -0.250  -0.015   0.047  -0.057
188   A         0.088   0.127   0.062   0.314   0.378   0.274  -0.015   0.047  -0.055
189   T         0.088   0.127   0.061   0.124   0.188   0.074  -0.015   0.047  -0.057
190   I        -1.180  -1.171  -1.160  -1.051  -1.052  -1.016  -1.011  -0.996  -0.975
191   G         1.833   1.843   1.858   2.032   2.041   2.071   1.976   1.987   2.007
192   Y         0.088   0.035   0.034  -0.086  -0.161  -0.158  -0.015  -0.097  -0.100
193   K         0.088   0.127   0.061   0.024   0.085  -0.010  -0.015   0.047  -0.057
194   P        -1.180  -1.171  -1.160  -1.051  -1.013  -1.016  -1.011  -0.996  -0.975
195   N        -1.180  -1.171  -1.160  -0.937  -0.927  -0.903  -1.011  -0.996  -0.975
196   N        -1.180  -1.171  -1.160  -0.996  -0.983  -0.962  -1.011  -0.996  -0.975
197   K         0.088   0.127   0.061   0.020   0.074  -0.014  -0.015   0.047  -0.057
198   E         0.088   0.127   0.061  -0.069   0.005  -0.121  -0.015   0.047  -0.057
199   S        -1.180  -1.171  -1.160  -1.122  -1.108  -1.088  -1.011  -0.996  -0.975
200   -        -0.068  -0.063  -0.046  -0.074  -0.060  -0.038  -0.264  -0.256  -0.229
201   -        -0.068  -0.063  -0.046  -0.057  -0.034  -0.021  -0.264  -0.256  -0.229
202   -        -0.068  -0.063  -0.046   0.010   0.017   0.046  -0.264  -0.256  -0.229
203   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
204   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
205   -         1.833   1.843   1.858   1.961   1.974   2.000   1.976   1.987   2.007
206   -        -0.068  -0.063  -0.046  -0.292  -0.279  -0.256  -0.264  -0.256  -0.229
207   -        -0.068  -0.063  -0.046  -0.337  -0.324  -0.301  -0.264  -0.256  -0.229
208   Y        -1.180  -1.171  -1.160  -1.242  -1.210  -1.208  -1.011  -0.996  -0.975
209   E         0.088   0.127   0.062   0.083   0.150   0.049  -0.015   0.047  -0.055
210   I         0.088   0.035   0.034  -0.204  -0.291  -0.296  -0.015  -0.097  -0.100
211   T         1.833   1.843   1.858   1.943   1.955   1.983   1.976   1.987   2.007
212   G        -1.180  -1.171  -1.160  -0.746  -0.737  -0.711  -1.011  -0.996  -0.975
213   F         1.833   1.843   1.858   1.817   1.833   1.856   1.976   1.987   2.007
214   T         1.833   1.843   1.858   1.943   1.955   1.983   1.976   1.987   2.007
215   S         1.833   1.843   1.858   1.808   1.820   1.847   1.976   1.987   2.007
216   M         0.088   0.035   0.034   0.181   0.111   0.115  -0.015  -0.097  -0.100
217   G         0.088   0.035   0.034   0.439   0.345   0.347  -0.015  -0.097  -0.100
218   N         0.088   0.035   0.034   0.266   0.184   0.171  -0.015  -0.097  -0.100
219   G         0.088   0.035   0.034   0.210   0.124   0.128  -0.015  -0.097  -0.100
220   Y         0.088   0.035   0.034   0.214   0.124   0.129  -0.015  -0.097  -0.100
221   G         0.088   0.035   0.034   0.314   0.230   0.227  -0.015  -0.097  -0.100
222   I         0.088   0.035   0.034   0.274   0.177   0.163  -0.015  -0.097  -0.100
223   K        -1.180  -1.171  -1.160  -1.002  -1.014  -0.967  -1.011  -0.996  -0.975
224   L        -1.180  -1.171  -1.160  -1.402  -1.395  -1.368  -1.011  -0.996  -0.975
225   F         0.088   0.035   0.034  -0.178  -0.260  -0.265  -0.015  -0.097  -0.100
226   N         0.088   0.035   0.034   0.054  -0.031  -0.032  -0.015  -0.097  -0.100
227   Y        -1.180  -1.171  -1.160  -1.040  -1.022  -1.005  -1.011  -0.996  -0.975
228   S        -1.180  -1.171  -1.160  -1.196  -1.191  -1.161  -1.011  -0.996  -0.975
229   V         0.088   0.035   0.034   0.020  -0.068  -0.063  -0.015  -0.097  -0.100
230   I        -1.180  -1.171  -1.160  -1.084  -1.086  -1.049  -1.011  -0.996  -0.975
231   H        -1.180  -1.171  -1.160  -0.906  -0.880  -0.871  -1.011  -0.996  -0.975
232   -        -0.068  -0.063  -0.046   0.166   0.174   0.202  -0.264  -0.256  -0.229
233   M         0.088   0.035   0.034  -0.001  -0.064  -0.058  -0.015  -0.097  -0.100
234   M         0.088   0.035   0.034  -0.001  -0.064  -0.058  -0.015  -0.097  -0.100
235   R        -1.180  -1.171  -1.160  -1.122  -1.080  -1.088  -1.011  -0.996  -0.975
236   S         0.088   0.127   0.062   0.149   0.206   0.118  -0.015   0.047  -0.055
237   H        -1.180  -1.171  -1.160  -0.943  -0.903  -0.908  -1.011  -0.996  -0.975
238   K        -1.180  -1.171  -1.160  -1.040  -1.042  -1.005  -1.011  -0.996  -0.975
239   C        -1.180  -1.171  -1.160  -0.787  -0.761  -0.752  -1.011  -0.996  -0.975
240   K        -1.180  -1.171  -1.160  -1.330  -1.318  -1.296  -1.011  -0.996  -0.975
241   R        -0.068  -0.063  -0.046  -0.174  -0.166  -0.138  -0.264  -0.256  -0.229
242   V        -0.068  -0.063  -0.046  -0.255  -0.247  -0.219  -0.264  -0.256  -0.229
243   V         0.088   0.035   0.034   0.062  -0.028  -0.022  -0.015  -0.097  -0.100
244   -        -0.068  -0.063  -0.046  -0.057  -0.051  -0.021  -0.264  -0.256  -0.229
245   -         1.833   1.843   1.858   2.169   2.184   2.208   1.976   1.987   2.007
246   -        -0.068  -0.063  -0.046  -0.195  -0.190  -0.159  -0.264  -0.256  -0.229
247   -        -0.068  -0.063  -0.046  -0.419  -0.416  -0.383  -0.264  -0.256  -0.229
248   -        -0.068  -0.063  -0.046  -0.346  -0.343  -0.310  -0.264  -0.256  -0.229
249   -        -0.068  -0.063  -0.046  -0.108  -0.103  -0.072  -0.264  -0.256  -0.229
250   -        -0.068  -0.063  -0.046  -0.169  -0.164  -0.133  -0.264  -0.256  -0.229
251   -        -0.068  -0.063  -0.046  -0.204  -0.199  -0.168  -0.264  -0.256  -0.229
252   -        -0.068  -0.063  -0.046   0.262   0.271   0.298  -0.264  -0.256  -0.229
253   -        -0.068  -0.063  -0.046  -0.169  -0.155  -0.133  -0.264  -0.256  -0.229
254   -        -0.068  -0.063  -0.046  -0.195  -0.190  -0.159  -0.264  -0.256  -0.229
255   -        -0.068  -0.063  -0.046  -0.057  -0.051  -0.021  -0.264  -0.256  -0.229
256   -        -0.068  -0.063  -0.046  -0.484  -0.482  -0.448  -0.264  -0.256  -0.229
257   -         1.833   1.843   1.858   2.157   2.173   2.197   1.976   1.987   2.007
258   A         1.833   1.843   1.858   2.041   2.060   2.080   1.976   1.987   2.007
259   D         0.088   0.127   0.062  -0.014   0.056  -0.061  -0.015   0.047  -0.055
260   I         0.088   0.035   0.034   0.103  -0.002  -0.000  -0.015  -0.097  -0.100
261   I         1.833   1.843   1.858   1.763   1.776   1.801   1.976   1.987   2.007
262   M        -1.180  -1.171  -1.160  -0.932  -0.896  -0.897  -1.011  -0.996  -0.975
263   E         1.833   1.843   1.858   1.781   1.803   1.820   1.976   1.987   2.007
264   H         1.833   1.843   1.858   2.102   2.121   2.141   1.976   1.987   2.007
265   D        -1.180  -1.171  -1.160  -1.167  -1.161  -1.133  -1.011  -0.996  -0.975
266   L         1.833   1.843   1.858   1.614   1.632   1.653   1.976   1.987   2.007
267   L         0.088   0.035   0.034   0.037  -0.076  -0.079  -0.015  -0.097  -0.100
268   G         0.088   0.035   0.034   0.079   0.004   0.002  -0.015  -0.097  -0.100
269   Y         1.833   1.843   1.858   2.006   2.014   2.045   1.976   1.987   2.007
270   Y         1.833   1.843   1.858   2.006   2.014   2.045   1.976   1.987   2.007
271   E        -1.180  -1.171  -1.160  -1.184  -1.173  -1.150  -1.011  -0.996  -0.975
272   K         0.088   0.127   0.062  -0.086  -0.025  -0.130  -0.015   0.047  -0.055
273   K         1.833   1.843   1.858   1.716   1.729   1.755   1.976   1.987   2.007
274   L         0.088   0.035   0.034   0.266   0.156   0.142  -0.015  -0.097  -0.100
275   G         0.088   0.127   0.061   0.206   0.268   0.154  -0.015   0.047  -0.057
276   F         1.833   1.843   1.858   1.817   1.833   1.856   1.976   1.987   2.007
277   V        -1.180  -1.171  -1.160  -1.100  -1.083  -1.066  -1.011  -0.996  -0.975
278   E        -1.180  -1.171  -1.160  -1.324  -1.302  -1.290  -1.011  -0.996  -0.975
279   V         0.088   0.035   0.034   0.062  -0.028  -0.022  -0.015  -0.097  -0.100
280   Q         0.088   0.035   0.034   0.165   0.092   0.098  -0.015  -0.097  -0.100
281   R        -1.180  -1.171  -1.160  -0.906  -0.877  -0.871  -1.011  -0.996  -0.975
282   F        -0.068  -0.063  -0.046  -0.224  -0.216  -0.188  -0.264  -0.256  -0.229
283   K        -0.068  -0.063  -0.046  -0.358  -0.350  -0.322  -0.264  -0.256  -0.229
284   V         0.088   0.035   0.034   0.020  -0.068  -0.063  -0.015  -0.097  -0.100
285   L         1.833   1.843   1.858   1.614   1.632   1.653   1.976   1.987   2.007
286   K         0.088   0.035   0.034  -0.086  -0.184  -0.187  -0.015  -0.097  -0.100
287   E         0.088   0.127   0.061  -0.069   0.005  -0.121  -0.015   0.047  -0.057
288   Q         0.088   0.035   0.034   0.286   0.203   0.213  -0.015  -0.097  -0.100
289   H         0.088   0.035   0.034   0.136   0.065   0.065  -0.015  -0.097  -0.100
290   Q        -1.180  -1.171  -1.160  -0.959  -0.927  -0.924  -1.011  -0.996  -0.975
291   V        -1.180  -1.171  -1.160  -0.959  -0.955  -0.924  -1.011  -0.996  -0.975
292   K        -1.180  -1.171  -1.160  -0.948  -0.961  -0.913  -1.011  -0.996  -0.975
293   -         1.833   1.843   1.858   1.806   1.831   1.845   1.976   1.987   2.007
294   -        -0.068  -0.063  -0.046  -0.248  -0.243  -0.212  -0.264  -0.256  -0.229
295   -        -0.068  -0.063  -0.046  -0.310  -0.297  -0.274  -0.264  -0.256  -0.229
296   -        -0.068  -0.063  -0.046  -0.248  -0.243  -0.212  -0.264  -0.256  -0.229
297   -        -0.068  -0.063  -0.046  -0.015  -0.009   0.021  -0.264  -0.256  -0.229
298   V         0.088   0.127   0.062   0.270   0.324   0.236  -0.015   0.047  -0.055
299   F         0.088   0.127   0.061  -0.082  -0.008  -0.139  -0.015   0.047  -0.057
300   D         0.088   0.035   0.034  -0.027  -0.111  -0.121  -0.015  -0.097  -0.100
301   D         0.088   0.127   0.061  -0.044   0.024  -0.095  -0.015   0.047  -0.057
302   K        -1.180  -1.171  -1.160  -1.095  -1.101  -1.060  -1.011  -0.996  -0.975
303   V         0.088   0.035   0.034   0.020  -0.068  -0.063  -0.015  -0.097  -0.100
304   D         0.088   0.035   0.034  -0.182  -0.265  -0.270  -0.015  -0.097  -0.100
305   F         0.088   0.035   0.034   0.218   0.126   0.115  -0.015  -0.097  -0.100
306   T         0.088   0.127   0.061   0.124   0.188   0.074  -0.015   0.047  -0.057
307   K         0.088   0.127   0.062   0.020   0.074  -0.013  -0.015   0.047  -0.055
308   D         0.088   0.127   0.062   0.054   0.116   0.014  -0.015   0.047  -0.055
309   F         1.833   1.843   1.858   1.817   1.833   1.856   1.976   1.987   2.007
310   H         1.833   1.843   1.858   2.102   2.121   2.141   1.976   1.987   2.007
311   V         0.088   0.127   0.061   0.037   0.103  -0.023  -0.015   0.047  -0.057
312   I         0.088   0.035   0.034  -0.022  -0.119  -0.121  -0.015  -0.097  -0.100
313   K         0.088   0.035   0.034  -0.035  -0.132  -0.138  -0.015  -0.097  -0.100
314   M        -1.180  -1.171  -1.160  -1.162  -1.116  -1.127  -1.011  -0.996  -0.975
315   I        -1.180  -1.171  -1.160  -1.111  -1.101  -1.077  -1.011  -0.996  -0.975
316   K         0.088   0.035   0.034   0.173   0.079   0.062  -0.015  -0.097  -0.100
317   E         0.088   0.127   0.061  -0.048   0.025  -0.097  -0.015   0.047  -0.057
318   L         0.088   0.035   0.034  -0.134  -0.235  -0.244  -0.015  -0.097  -0.100
319   G         0.088   0.035   0.034   0.369   0.283   0.280  -0.015  -0.097  -0.100
320   N         0.088   0.035   0.034   0.012  -0.073  -0.072  -0.015  -0.097  -0.100
321   H        -0.068  -0.063  -0.046  -0.046  -0.037  -0.010  -0.264  -0.256  -0.229
322   R        -0.068  -0.063  -0.046   0.117   0.125   0.153  -0.264  -0.256  -0.229
323   L        -0.068  -0.063  -0.046  -0.496  -0.489  -0.460  -0.264  -0.256  -0.229
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P39975
Output conservation file - output/P39975
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
