1     M         1.086   1.091   1.102   1.313   1.316   1.332   1.126   1.131   1.143
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     V        -1.494  -1.477  -1.444  -1.500  -1.481  -1.413  -1.340  -1.313  -1.259
4     S        -0.409  -0.465  -0.474  -0.438  -0.529  -0.543  -0.518  -0.600  -0.611
5     D        -1.494  -1.477  -1.444  -1.349  -1.303  -1.266  -1.340  -1.313  -1.259
6     W        -0.409  -0.465  -0.474  -0.263  -0.343  -0.357  -0.518  -0.600  -0.611
7     K        -1.494  -1.477  -1.444  -1.481  -1.438  -1.394  -1.340  -1.313  -1.259
8     N        -1.494  -1.477  -1.444  -1.201  -1.168  -1.122  -1.340  -1.313  -1.259
9     F         1.086   1.091   1.102   0.998   1.009   1.025   1.126   1.131   1.143
10    C        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    L         1.086   1.091   1.102   0.774   0.782   0.806   1.126   1.131   1.143
12    E        -0.542  -0.536  -0.504  -0.364  -0.354  -0.305  -0.723  -0.710  -0.658
13    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    S         1.086   1.091   1.102   1.099   1.107   1.123   1.126   1.131   1.143
16    R        -0.542  -0.536  -0.504  -0.813  -0.802  -0.743  -0.723  -0.710  -0.658
17    F        -1.494  -1.477  -1.444  -1.327  -1.315  -1.244  -1.340  -1.313  -1.259
18    R        -0.409  -0.366  -0.454  -0.367  -0.296  -0.458  -0.518  -0.451  -0.581
19    P         1.086   1.091   1.102   1.164   1.176   1.187   1.126   1.131   1.143
20    T        -0.409  -0.366  -0.454  -0.426  -0.354  -0.500  -0.518  -0.451  -0.581
21    I        -1.494  -1.477  -1.444  -1.747  -1.706  -1.654  -1.340  -1.313  -1.259
22    D         1.086   1.091   1.102   1.313   1.321   1.332   1.126   1.131   1.143
23    R         1.086   1.091   1.102   1.182   1.191   1.205   1.126   1.131   1.143
24    P         1.086   1.091   1.102   1.164   1.176   1.187   1.126   1.131   1.143
25    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    F         1.086   1.091   1.102   0.998   1.009   1.025   1.126   1.131   1.143
27    N        -0.409  -0.465  -0.474  -0.293  -0.370  -0.380  -0.518  -0.600  -0.611
28    I         1.086   1.091   1.102   1.005   1.021   1.031   1.126   1.131   1.143
29    Y        -0.409  -0.362  -0.454  -0.331  -0.267  -0.383  -0.518  -0.444  -0.581
30    L         1.086   1.091   1.102   0.782   0.788   0.814   1.126   1.131   1.143
31    W         1.086   1.091   1.102   1.272   1.278   1.292   1.126   1.131   1.143
32    D        -1.494  -1.477  -1.444  -1.276  -1.231  -1.195  -1.340  -1.313  -1.259
33    Y        -0.409  -0.465  -0.474  -0.506  -0.593  -0.611  -0.518  -0.600  -0.611
34    F         1.086   1.091   1.102   0.998   1.009   1.025   1.126   1.131   1.143
35    N        -1.494  -1.477  -1.444  -1.180  -1.148  -1.101  -1.340  -1.313  -1.259
36    R        -1.494  -1.477  -1.444  -1.201  -1.182  -1.122  -1.340  -1.313  -1.259
37    A         1.086   1.091   1.102   1.060   1.067   1.085   1.126   1.131   1.143
38    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    W        -0.409  -0.362  -0.454  -0.287  -0.204  -0.385  -0.518  -0.444  -0.581
41    A        -0.409  -0.465  -0.474  -0.255  -0.359  -0.387  -0.518  -0.600  -0.611
42    T        -1.494  -1.477  -1.444  -1.405  -1.382  -1.320  -1.340  -1.313  -1.259
43    A        -1.494  -1.477  -1.444  -1.709  -1.672  -1.617  -1.340  -1.313  -1.259
44    G        -1.494  -1.477  -1.444  -1.531  -1.491  -1.444  -1.340  -1.313  -1.259
45    R        -0.409  -0.465  -0.474  -0.342  -0.425  -0.443  -0.518  -0.600  -0.611
46    F        -1.494  -1.477  -1.444  -1.401  -1.386  -1.316  -1.340  -1.313  -1.259
47    Q        -0.409  -0.465  -0.474  -0.255  -0.335  -0.346  -0.518  -0.600  -0.611
48    P        -0.409  -0.465  -0.474  -0.407  -0.492  -0.503  -0.518  -0.600  -0.611
49    K        -1.494  -1.477  -1.444  -1.258  -1.232  -1.177  -1.340  -1.313  -1.259
50    D        -0.409  -0.366  -0.454  -0.206  -0.133  -0.298  -0.518  -0.451  -0.581
51    F         1.086   1.091   1.102   0.998   1.009   1.025   1.126   1.131   1.143
52    E        -1.494  -1.477  -1.444  -1.319  -1.273  -1.237  -1.340  -1.313  -1.259
53    F         1.086   1.091   1.102   0.998   1.009   1.025   1.126   1.131   1.143
54    T        -0.409  -0.465  -0.474  -0.501  -0.598  -0.603  -0.518  -0.600  -0.611
55    V        -1.494  -1.477  -1.444  -1.390  -1.378  -1.305  -1.340  -1.313  -1.259
56    G        -0.409  -0.366  -0.454  -0.293  -0.226  -0.353  -0.518  -0.451  -0.581
57    K        -1.494  -1.477  -1.444  -1.132  -1.116  -1.054  -1.340  -1.313  -1.259
58    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
59    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
60    Q        -1.494  -1.477  -1.444  -1.378  -1.326  -1.295  -1.340  -1.313  -1.259
61    P         1.086   1.091   1.102   1.164   1.176   1.187   1.126   1.131   1.143
62    L        -1.494  -1.477  -1.444  -1.543  -1.549  -1.455  -1.340  -1.313  -1.259
63    S         1.086   1.091   1.102   1.097   1.108   1.121   1.126   1.131   1.143
64    E        -1.494  -1.477  -1.444  -1.330  -1.285  -1.248  -1.340  -1.313  -1.259
65    P        -1.494  -1.477  -1.444  -1.595  -1.541  -1.505  -1.340  -1.313  -1.259
66    R        -1.494  -1.477  -1.444  -1.276  -1.247  -1.195  -1.340  -1.313  -1.259
67    P        -0.409  -0.362  -0.454  -0.260  -0.185  -0.324  -0.518  -0.444  -0.581
68    V        -0.409  -0.362  -0.454  -0.501  -0.431  -0.571  -0.518  -0.444  -0.581
69    L        -1.494  -1.477  -1.444  -1.684  -1.673  -1.593  -1.340  -1.313  -1.259
70    L        -0.409  -0.465  -0.474  -0.635  -0.743  -0.778  -0.518  -0.600  -0.611
71    F        -0.409  -0.366  -0.454  -0.512  -0.440  -0.583  -0.518  -0.451  -0.581
72    I         1.086   1.091   1.102   1.005   1.021   1.031   1.126   1.131   1.143
73    A        -1.494  -1.477  -1.444  -1.567  -1.533  -1.478  -1.340  -1.313  -1.259
74    M        -1.494  -1.477  -1.444  -1.405  -1.355  -1.320  -1.340  -1.313  -1.259
75    Y         1.086   1.091   1.102   1.060   1.066   1.085   1.126   1.131   1.143
76    Y         1.086   1.091   1.102   1.060   1.066   1.085   1.126   1.131   1.143
77    V        -1.494  -1.477  -1.444  -1.559  -1.532  -1.470  -1.340  -1.313  -1.259
78    V        -0.409  -0.362  -0.454  -0.532  -0.457  -0.609  -0.518  -0.444  -0.581
79    I         1.086   1.091   1.102   1.005   1.021   1.031   1.126   1.131   1.143
80    F         1.086   1.091   1.102   0.998   1.009   1.025   1.126   1.131   1.143
81    G         1.086   1.091   1.102   1.122   1.135   1.145   1.126   1.131   1.143
82    G         1.086   1.091   1.102   1.122   1.135   1.145   1.126   1.131   1.143
83    R         1.086   1.091   1.102   1.182   1.191   1.205   1.126   1.131   1.143
84    S        -0.409  -0.465  -0.474  -0.239  -0.338  -0.366  -0.518  -0.600  -0.611
85    L        -0.409  -0.366  -0.454  -0.741  -0.678  -0.801  -0.518  -0.451  -0.581
86    V        -0.409  -0.465  -0.474  -0.247  -0.364  -0.389  -0.518  -0.600  -0.611
87    K        -0.409  -0.465  -0.474  -0.282  -0.373  -0.387  -0.518  -0.600  -0.611
88    S        -0.409  -0.465  -0.474  -0.228  -0.331  -0.356  -0.518  -0.600  -0.611
89    C        -1.494  -1.477  -1.444  -1.405  -1.350  -1.320  -1.340  -1.313  -1.259
90    K        -1.494  -1.477  -1.444  -1.258  -1.232  -1.177  -1.340  -1.313  -1.259
91    P         1.086   1.091   1.102   1.164   1.176   1.187   1.126   1.131   1.143
92    L        -1.494  -1.477  -1.444  -1.751  -1.735  -1.658  -1.340  -1.313  -1.259
93    K        -0.409  -0.366  -0.454  -0.277  -0.211  -0.352  -0.518  -0.451  -0.581
94    L         1.086   1.091   1.102   0.782   0.788   0.814   1.126   1.131   1.143
95    R        -0.409  -0.366  -0.454  -0.239  -0.175  -0.303  -0.518  -0.451  -0.581
96    F        -1.494  -1.477  -1.444  -1.393  -1.377  -1.309  -1.340  -1.313  -1.259
97    I        -0.409  -0.465  -0.474  -0.741  -0.827  -0.831  -0.518  -0.600  -0.611
98    S        -0.409  -0.465  -0.474  -0.495  -0.581  -0.594  -0.518  -0.600  -0.611
99    Q        -0.409  -0.362  -0.454  -0.365  -0.276  -0.483  -0.518  -0.444  -0.581
100   V        -0.409  -0.465  -0.474  -0.532  -0.626  -0.644  -0.518  -0.600  -0.611
101   H         1.086   1.091   1.102   1.325   1.332   1.344   1.126   1.131   1.143
102   N         1.086   1.091   1.102   1.290   1.294   1.309   1.126   1.131   1.143
103   L        -1.494  -1.477  -1.444  -1.751  -1.735  -1.658  -1.340  -1.313  -1.259
104   M        -1.494  -1.477  -1.444  -1.375  -1.327  -1.291  -1.340  -1.313  -1.259
105   L         1.086   1.091   1.102   0.782   0.788   0.814   1.126   1.131   1.143
106   T         1.086   1.091   1.102   1.073   1.082   1.098   1.126   1.131   1.143
107   S        -1.494  -1.477  -1.444  -1.647  -1.603  -1.557  -1.340  -1.313  -1.259
108   V        -1.494  -1.477  -1.444  -1.747  -1.709  -1.654  -1.340  -1.313  -1.259
109   S         1.086   1.091   1.102   1.097   1.108   1.121   1.126   1.131   1.143
110   F        -1.494  -1.477  -1.444  -1.496  -1.470  -1.409  -1.340  -1.313  -1.259
111   L        -1.494  -1.477  -1.444  -1.539  -1.541  -1.451  -1.340  -1.313  -1.259
112   W        -0.409  -0.465  -0.474  -0.609  -0.679  -0.661  -0.518  -0.600  -0.611
113   L         1.086   1.091   1.102   0.782   0.788   0.814   1.126   1.131   1.143
114   I        -1.494  -1.477  -1.444  -1.709  -1.668  -1.617  -1.340  -1.313  -1.259
115   L         1.086   1.091   1.102   0.782   0.788   0.814   1.126   1.131   1.143
116   M        -1.494  -1.477  -1.444  -1.543  -1.482  -1.455  -1.340  -1.313  -1.259
117   V        -0.409  -0.362  -0.454  -0.532  -0.457  -0.609  -0.518  -0.444  -0.581
118   E         1.086   1.091   1.102   1.278   1.285   1.298   1.126   1.131   1.143
119   Q         1.086   1.091   1.102   1.290   1.295   1.309   1.126   1.131   1.143
120   M        -0.409  -0.465  -0.474  -0.588  -0.657  -0.635  -0.518  -0.600  -0.611
121   L        -0.409  -0.366  -0.454  -0.744  -0.676  -0.805  -0.518  -0.451  -0.581
122   P         1.086   1.091   1.102   1.164   1.176   1.187   1.126   1.131   1.143
123   I         1.086   1.091   1.102   1.005   1.021   1.031   1.126   1.131   1.143
124   V        -0.409  -0.366  -0.454  -0.532  -0.464  -0.609  -0.518  -0.451  -0.581
125   Y        -0.409  -0.465  -0.474  -0.506  -0.607  -0.611  -0.518  -0.600  -0.611
126   R         1.086   1.091   1.102   1.182   1.191   1.205   1.126   1.131   1.143
127   H        -1.494  -1.477  -1.444  -1.159  -1.122  -1.081  -1.340  -1.313  -1.259
128   G         1.086   1.091   1.102   1.122   1.135   1.145   1.126   1.131   1.143
129   L        -0.409  -0.465  -0.474  -0.635  -0.743  -0.778  -0.518  -0.600  -0.611
130   Y        -1.494  -1.477  -1.444  -1.713  -1.670  -1.621  -1.340  -1.313  -1.259
131   F        -1.494  -1.477  -1.444  -1.367  -1.356  -1.284  -1.340  -1.313  -1.259
132   A         1.086   1.091   1.102   1.060   1.067   1.085   1.126   1.131   1.143
133   V        -0.409  -0.465  -0.474  -0.532  -0.626  -0.644  -0.518  -0.600  -0.611
134   C         1.086   1.091   1.102   1.349   1.355   1.367   1.126   1.131   1.143
135   N        -1.494  -1.477  -1.444  -1.050  -1.030  -0.974  -1.340  -1.313  -1.259
136   V        -1.494  -1.477  -1.444  -1.567  -1.542  -1.478  -1.340  -1.313  -1.259
137   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
138   E        -0.409  -0.465  -0.474  -0.298  -0.375  -0.387  -0.518  -0.600  -0.611
139   S        -0.409  -0.362  -0.454  -0.393  -0.312  -0.466  -0.518  -0.444  -0.581
140   W         1.086   1.091   1.102   1.272   1.278   1.292   1.126   1.131   1.143
141   T         1.086   1.091   1.102   1.073   1.082   1.098   1.126   1.131   1.143
142   Q         1.086   1.091   1.102   1.290   1.295   1.309   1.126   1.131   1.143
143   P         1.086   1.091   1.102   1.164   1.176   1.187   1.126   1.131   1.143
144   M        -1.494  -1.477  -1.444  -1.539  -1.474  -1.451  -1.340  -1.313  -1.259
145   E        -0.409  -0.465  -0.474  -0.404  -0.487  -0.480  -0.518  -0.600  -0.611
146   T        -1.494  -1.477  -1.444  -1.563  -1.529  -1.474  -1.340  -1.313  -1.259
147   L        -0.409  -0.366  -0.454  -0.570  -0.518  -0.596  -0.518  -0.451  -0.581
148   Y         1.086   1.091   1.102   1.060   1.066   1.085   1.126   1.131   1.143
149   Y         1.086   1.091   1.102   1.060   1.066   1.085   1.126   1.131   1.143
150   L         1.086   1.091   1.102   0.782   0.788   0.814   1.126   1.131   1.143
151   N         1.086   1.091   1.102   1.290   1.294   1.309   1.126   1.131   1.143
152   Y         1.086   1.091   1.102   1.060   1.066   1.085   1.126   1.131   1.143
153   M        -0.409  -0.465  -0.474  -0.588  -0.657  -0.635  -0.518  -0.600  -0.611
154   T         1.086   1.091   1.102   1.073   1.082   1.098   1.126   1.131   1.143
155   K         1.086   1.091   1.102   1.194   1.199   1.216   1.126   1.131   1.143
156   F        -0.409  -0.465  -0.474  -0.483  -0.584  -0.602  -0.518  -0.600  -0.611
157   V        -1.494  -1.477  -1.444  -1.751  -1.716  -1.658  -1.340  -1.313  -1.259
158   E         1.086   1.091   1.102   1.278   1.285   1.298   1.126   1.131   1.143
159   F        -0.409  -0.465  -0.474  -0.744  -0.834  -0.835  -0.518  -0.600  -0.611
160   A        -1.494  -1.477  -1.444  -1.709  -1.661  -1.617  -1.340  -1.313  -1.259
161   D         1.086   1.091   1.102   1.313   1.321   1.332   1.126   1.131   1.143
162   T         1.086   1.091   1.102   1.073   1.082   1.098   1.126   1.131   1.143
163   V        -0.409  -0.362  -0.454  -0.370  -0.313  -0.415  -0.518  -0.444  -0.581
164   L        -0.409  -0.465  -0.474  -0.641  -0.754  -0.783  -0.518  -0.600  -0.611
165   M        -0.409  -0.465  -0.474  -0.588  -0.657  -0.635  -0.518  -0.600  -0.611
166   V        -0.409  -0.362  -0.454  -0.535  -0.462  -0.613  -0.518  -0.444  -0.581
167   L         1.086   1.091   1.102   0.782   0.788   0.814   1.126   1.131   1.143
168   K        -0.409  -0.366  -0.454  -0.277  -0.211  -0.352  -0.518  -0.451  -0.581
169   H        -0.409  -0.465  -0.474  -0.212  -0.296  -0.302  -0.518  -0.600  -0.611
170   R        -0.409  -0.465  -0.474  -0.277  -0.370  -0.385  -0.518  -0.600  -0.611
171   K        -0.409  -0.362  -0.454  -0.285  -0.210  -0.361  -0.518  -0.444  -0.581
172   L         1.086   1.091   1.102   0.782   0.788   0.814   1.126   1.131   1.143
173   T         1.086   1.091   1.102   1.073   1.082   1.098   1.126   1.131   1.143
174   F         1.086   1.091   1.102   0.998   1.009   1.025   1.126   1.131   1.143
175   L         1.086   1.091   1.102   0.782   0.788   0.814   1.126   1.131   1.143
176   H         1.086   1.091   1.102   1.325   1.332   1.344   1.126   1.131   1.143
177   T        -0.409  -0.362  -0.454  -0.309  -0.242  -0.360  -0.518  -0.444  -0.581
178   Y         1.086   1.091   1.102   1.060   1.066   1.085   1.126   1.131   1.143
179   H         1.086   1.091   1.102   1.325   1.332   1.344   1.126   1.131   1.143
180   H         1.086   1.091   1.102   1.325   1.332   1.344   1.126   1.131   1.143
181   G         1.086   1.091   1.102   1.122   1.135   1.145   1.126   1.131   1.143
182   A         1.086   1.091   1.102   1.060   1.067   1.085   1.126   1.131   1.143
183   T         1.086   1.091   1.102   1.073   1.082   1.098   1.126   1.131   1.143
184   A         1.086   1.091   1.102   1.060   1.067   1.085   1.126   1.131   1.143
185   L         1.086   1.091   1.102   0.782   0.788   0.814   1.126   1.131   1.143
186   L         1.086   1.091   1.102   0.782   0.788   0.814   1.126   1.131   1.143
187   C         1.086   1.091   1.102   1.349   1.355   1.367   1.126   1.131   1.143
188   Y         1.086   1.091   1.102   1.060   1.066   1.085   1.126   1.131   1.143
189   N        -0.409  -0.465  -0.474  -0.337  -0.416  -0.419  -0.518  -0.600  -0.611
190   Q         1.086   1.091   1.102   1.290   1.295   1.309   1.126   1.131   1.143
191   L         1.086   1.091   1.102   0.782   0.788   0.814   1.126   1.131   1.143
192   V        -0.409  -0.465  -0.474  -0.532  -0.626  -0.644  -0.518  -0.600  -0.611
193   G         1.086   1.091   1.102   1.122   1.135   1.145   1.126   1.131   1.143
194   Y        -1.494  -1.477  -1.444  -1.390  -1.371  -1.305  -1.340  -1.313  -1.259
195   T         1.086   1.091   1.102   1.073   1.082   1.098   1.126   1.131   1.143
196   A        -0.409  -0.465  -0.474  -0.421  -0.515  -0.535  -0.518  -0.600  -0.611
197   V         1.086   1.091   1.102   1.005   1.005   1.031   1.126   1.131   1.143
198   T        -0.409  -0.465  -0.474  -0.415  -0.507  -0.527  -0.518  -0.600  -0.611
199   W         1.086   1.091   1.102   1.272   1.278   1.292   1.126   1.131   1.143
200   V         1.086   1.091   1.102   1.005   1.005   1.031   1.126   1.131   1.143
201   P         1.086   1.091   1.102   1.164   1.176   1.187   1.126   1.131   1.143
202   V        -0.409  -0.465  -0.474  -0.532  -0.626  -0.644  -0.518  -0.600  -0.611
203   T         1.086   1.091   1.102   1.073   1.082   1.098   1.126   1.131   1.143
204   L         1.086   1.091   1.102   0.782   0.788   0.814   1.126   1.131   1.143
205   N         1.086   1.091   1.102   1.290   1.294   1.309   1.126   1.131   1.143
206   L         1.086   1.091   1.102   0.782   0.788   0.814   1.126   1.131   1.143
207   A        -1.494  -1.477  -1.444  -1.527  -1.494  -1.440  -1.340  -1.313  -1.259
208   V         1.086   1.091   1.102   1.005   1.005   1.031   1.126   1.131   1.143
209   H         1.086   1.091   1.102   1.325   1.332   1.344   1.126   1.131   1.143
210   V         1.086   1.091   1.102   1.005   1.005   1.031   1.126   1.131   1.143
211   L        -0.409  -0.465  -0.474  -0.635  -0.758  -0.778  -0.518  -0.600  -0.611
212   M         1.086   1.091   1.102   1.313   1.316   1.332   1.126   1.131   1.143
213   Y         1.086   1.091   1.102   1.060   1.066   1.085   1.126   1.131   1.143
214   W        -0.409  -0.366  -0.454  -0.287  -0.212  -0.385  -0.518  -0.451  -0.581
215   Y         1.086   1.091   1.102   1.060   1.066   1.085   1.126   1.131   1.143
216   Y         1.086   1.091   1.102   1.060   1.066   1.085   1.126   1.131   1.143
217   F         1.086   1.091   1.102   0.998   1.009   1.025   1.126   1.131   1.143
218   L        -0.409  -0.362  -0.454  -0.600  -0.539  -0.631  -0.518  -0.444  -0.581
219   S        -0.409  -0.366  -0.454  -0.421  -0.348  -0.499  -0.518  -0.451  -0.581
220   A         1.086   1.091   1.102   1.060   1.067   1.085   1.126   1.131   1.143
221   S        -0.409  -0.465  -0.474  -0.326  -0.421  -0.444  -0.518  -0.600  -0.611
222   G         1.086   1.091   1.102   1.122   1.135   1.145   1.126   1.131   1.143
223   I         1.086   1.091   1.102   1.005   1.021   1.031   1.126   1.131   1.143
224   R         1.086   1.091   1.102   1.182   1.191   1.205   1.126   1.131   1.143
225   V        -0.409  -0.362  -0.454  -0.532  -0.457  -0.609  -0.518  -0.444  -0.581
226   W         1.086   1.091   1.102   1.272   1.278   1.292   1.126   1.131   1.143
227   W         1.086   1.091   1.102   1.272   1.278   1.292   1.126   1.131   1.143
228   K         1.086   1.091   1.102   1.194   1.199   1.216   1.126   1.131   1.143
229   A        -0.409  -0.465  -0.474  -0.255  -0.359  -0.387  -0.518  -0.600  -0.611
230   W         1.086   1.091   1.102   1.272   1.278   1.292   1.126   1.131   1.143
231   V        -0.409  -0.362  -0.454  -0.532  -0.457  -0.609  -0.518  -0.444  -0.581
232   T         1.086   1.091   1.102   1.073   1.082   1.098   1.126   1.131   1.143
233   R         1.086   1.091   1.102   1.182   1.191   1.205   1.126   1.131   1.143
234   L         1.086   1.091   1.102   0.782   0.788   0.814   1.126   1.131   1.143
235   Q         1.086   1.091   1.102   1.290   1.295   1.309   1.126   1.131   1.143
236   I         1.086   1.091   1.102   1.005   1.021   1.031   1.126   1.131   1.143
237   V        -0.409  -0.465  -0.474  -0.532  -0.626  -0.644  -0.518  -0.600  -0.611
238   Q         1.086   1.091   1.102   1.290   1.295   1.309   1.126   1.131   1.143
239   F         1.086   1.091   1.102   0.998   1.009   1.025   1.126   1.131   1.143
240   M        -1.494  -1.477  -1.444  -1.405  -1.355  -1.320  -1.340  -1.313  -1.259
241   L        -0.409  -0.465  -0.474  -0.635  -0.743  -0.778  -0.518  -0.600  -0.611
242   D         1.086   1.091   1.102   1.313   1.321   1.332   1.126   1.131   1.143
243   L         1.086   1.091   1.102   0.782   0.788   0.814   1.126   1.131   1.143
244   I        -0.409  -0.465  -0.474  -0.424  -0.515  -0.547  -0.518  -0.600  -0.611
245   V        -0.409  -0.465  -0.474  -0.538  -0.637  -0.650  -0.518  -0.600  -0.611
246   V         1.086   1.091   1.102   1.005   1.005   1.031   1.126   1.131   1.143
247   Y         1.086   1.091   1.102   1.060   1.066   1.085   1.126   1.131   1.143
248   Y        -0.409  -0.465  -0.474  -0.512  -0.603  -0.616  -0.518  -0.600  -0.611
249   V        -0.409  -0.465  -0.474  -0.480  -0.585  -0.598  -0.518  -0.600  -0.611
250   L        -0.409  -0.465  -0.474  -0.547  -0.663  -0.698  -0.518  -0.600  -0.611
251   Y         1.086   1.091   1.102   1.060   1.066   1.085   1.126   1.131   1.143
252   Q        -0.409  -0.465  -0.474  -0.337  -0.415  -0.419  -0.518  -0.600  -0.611
253   K        -0.409  -0.465  -0.474  -0.393  -0.482  -0.485  -0.518  -0.600  -0.611
254   I        -0.409  -0.465  -0.474  -0.538  -0.628  -0.650  -0.518  -0.600  -0.611
255   V        -0.409  -0.465  -0.474  -0.469  -0.571  -0.588  -0.518  -0.600  -0.611
256   A        -0.409  -0.465  -0.474  -0.421  -0.515  -0.535  -0.518  -0.600  -0.611
257   A        -0.409  -0.465  -0.474  -0.443  -0.538  -0.555  -0.518  -0.600  -0.611
258   Y         1.086   1.091   1.102   1.060   1.066   1.085   1.126   1.131   1.143
259   F        -0.409  -0.366  -0.454  -0.412  -0.348  -0.464  -0.518  -0.451  -0.581
260   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
261   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
262   A        -0.409  -0.465  -0.474  -0.359  -0.455  -0.480  -0.518  -0.600  -0.611
263   C        -0.409  -0.465  -0.474  -0.132  -0.216  -0.228  -0.518  -0.600  -0.611
264   T        -0.409  -0.465  -0.474  -0.217  -0.324  -0.351  -0.518  -0.600  -0.611
265   P         1.086   1.091   1.102   1.164   1.176   1.187   1.126   1.131   1.143
266   Q        -0.409  -0.465  -0.474  -0.143  -0.234  -0.247  -0.518  -0.600  -0.611
267   C        -1.494  -1.477  -1.444  -1.166  -1.131  -1.088  -1.340  -1.313  -1.259
268   E        -0.409  -0.465  -0.474  -0.298  -0.375  -0.387  -0.518  -0.600  -0.611
269   D        -1.494  -1.477  -1.444  -1.237  -1.197  -1.156  -1.340  -1.313  -1.259
270   C         1.086   1.091   1.102   1.349   1.355   1.367   1.126   1.131   1.143
271   L        -0.409  -0.465  -0.474  -0.582  -0.700  -0.729  -0.518  -0.600  -0.611
272   G         1.086   1.091   1.102   1.122   1.135   1.145   1.126   1.131   1.143
273   S        -0.409  -0.465  -0.474  -0.239  -0.338  -0.366  -0.518  -0.600  -0.611
274   M        -0.409  -0.465  -0.474  -0.143  -0.231  -0.243  -0.518  -0.600  -0.611
275   T        -0.409  -0.465  -0.474  -0.506  -0.594  -0.609  -0.518  -0.600  -0.611
276   A         1.086   1.091   1.102   1.060   1.067   1.085   1.126   1.131   1.143
277   I        -0.409  -0.465  -0.474  -0.480  -0.576  -0.598  -0.518  -0.600  -0.611
278   A        -1.494  -1.477  -1.444  -1.571  -1.530  -1.482  -1.340  -1.313  -1.259
279   A        -1.494  -1.477  -1.444  -1.473  -1.447  -1.387  -1.340  -1.313  -1.259
280   G         1.086   1.091   1.102   1.122   1.135   1.145   1.126   1.131   1.143
281   A        -1.494  -1.477  -1.444  -1.349  -1.327  -1.266  -1.340  -1.313  -1.259
282   A        -0.409  -0.465  -0.474  -0.398  -0.491  -0.515  -0.518  -0.600  -0.611
283   I        -0.409  -0.366  -0.454  -0.635  -0.548  -0.734  -0.518  -0.451  -0.581
284   L         1.086   1.091   1.102   0.782   0.788   0.814   1.126   1.131   1.143
285   T        -0.409  -0.362  -0.454  -0.426  -0.347  -0.500  -0.518  -0.444  -0.581
286   S         1.086   1.091   1.102   1.097   1.108   1.121   1.126   1.131   1.143
287   Y         1.086   1.091   1.102   1.060   1.066   1.085   1.126   1.131   1.143
288   L         1.086   1.091   1.102   0.782   0.788   0.814   1.126   1.131   1.143
289   F        -0.409  -0.362  -0.454  -0.538  -0.460  -0.615  -0.518  -0.444  -0.581
290   L         1.086   1.091   1.102   0.782   0.788   0.814   1.126   1.131   1.143
291   F         1.086   1.091   1.102   0.998   1.009   1.025   1.126   1.131   1.143
292   I         1.086   1.091   1.102   1.005   1.021   1.031   1.126   1.131   1.143
293   S        -0.409  -0.366  -0.454  -0.421  -0.348  -0.499  -0.518  -0.451  -0.581
294   F         1.086   1.091   1.102   0.998   1.009   1.025   1.126   1.131   1.143
295   Y         1.086   1.091   1.102   1.060   1.066   1.085   1.126   1.131   1.143
296   I        -0.409  -0.362  -0.454  -0.535  -0.446  -0.613  -0.518  -0.444  -0.581
297   E        -1.494  -1.477  -1.444  -1.222  -1.190  -1.142  -1.340  -1.313  -1.259
298   V        -1.494  -1.477  -1.444  -1.500  -1.481  -1.413  -1.340  -1.313  -1.259
299   Y         1.086   1.091   1.102   1.060   1.066   1.085   1.126   1.131   1.143
300   K        -0.409  -0.366  -0.454  -0.277  -0.211  -0.352  -0.518  -0.451  -0.581
301   R        -0.409  -0.465  -0.474  -0.277  -0.370  -0.385  -0.518  -0.600  -0.611
302   G        -1.494  -1.477  -1.444  -1.240  -1.217  -1.160  -1.340  -1.313  -1.259
303   S        -0.409  -0.362  -0.454  -0.393  -0.312  -0.466  -0.518  -0.444  -0.581
304   A        -1.494  -1.477  -1.444  -1.390  -1.370  -1.305  -1.340  -1.313  -1.259
305   -        -0.542  -0.536  -0.504  -0.493  -0.482  -0.430  -0.723  -0.710  -0.658
306   -        -0.542  -0.536  -0.504  -0.626  -0.615  -0.560  -0.723  -0.710  -0.658
307   S        -1.494  -1.477  -1.444  -1.401  -1.369  -1.316  -1.340  -1.313  -1.259
308   G        -0.409  -0.366  -0.454  -0.381  -0.305  -0.459  -0.518  -0.451  -0.581
309   K        -0.409  -0.362  -0.454  -0.277  -0.204  -0.352  -0.518  -0.444  -0.581
310   K        -0.409  -0.366  -0.454  -0.285  -0.218  -0.361  -0.518  -0.451  -0.581
311   K        -1.494  -1.477  -1.444  -1.423  -1.389  -1.338  -1.340  -1.313  -1.259
312   I        -1.494  -1.477  -1.444  -1.747  -1.706  -1.654  -1.340  -1.313  -1.259
313   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
314   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
315   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
316   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
317   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
318   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
319   -        -0.542  -0.536  -0.504  -0.645  -0.634  -0.579  -0.723  -0.710  -0.658
320   -        -0.542  -0.536  -0.504  -0.864  -0.853  -0.793  -0.723  -0.710  -0.658
321   -        -0.542  -0.536  -0.504  -0.462  -0.451  -0.400  -0.723  -0.710  -0.658
322   -        -0.542  -0.536  -0.504  -0.487  -0.476  -0.424  -0.723  -0.710  -0.658
323   -         1.086   1.091   1.102   1.120   1.128   1.144   1.126   1.131   1.143
324   -        -0.542  -0.536  -0.504  -0.562  -0.551  -0.498  -0.723  -0.710  -0.658
325   -        -0.542  -0.536  -0.504  -0.487  -0.476  -0.424  -0.723  -0.710  -0.658
326   -        -0.542  -0.536  -0.504  -0.750  -0.738  -0.681  -0.723  -0.710  -0.658
327   -         1.086   1.091   1.102   1.067   1.075   1.092   1.126   1.131   1.143
328   -        -0.542  -0.536  -0.504  -0.499  -0.489  -0.437  -0.723  -0.710  -0.658
329   -         1.086   1.091   1.102   1.058   1.066   1.084   1.126   1.131   1.143
330   -        -0.542  -0.536  -0.504  -0.395  -0.384  -0.335  -0.723  -0.710  -0.658
331   -        -0.542  -0.536  -0.504  -0.684  -0.673  -0.617  -0.723  -0.710  -0.658
332   -        -0.542  -0.536  -0.504  -0.664  -0.653  -0.598  -0.723  -0.710  -0.658
333   -        -0.542  -0.536  -0.504  -0.671  -0.660  -0.604  -0.723  -0.710  -0.658
334   -        -0.542  -0.536  -0.504  -0.684  -0.673  -0.617  -0.723  -0.710  -0.658
335   -         1.086   1.091   1.102   1.164   1.172   1.186   1.126   1.131   1.143
336   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
337   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   -         1.086   1.091   1.102   1.085   1.093   1.110   1.126   1.131   1.143
339   -        -0.542  -0.536  -0.504  -0.512  -0.501  -0.449  -0.723  -0.710  -0.658
340   -        -0.542  -0.536  -0.504  -0.684  -0.673  -0.617  -0.723  -0.710  -0.658
341   -         1.086   1.091   1.102   1.067   1.075   1.092   1.126   1.131   1.143
342   -        -0.542  -0.536  -0.504  -0.684  -0.673  -0.617  -0.723  -0.710  -0.658
343   -         1.086   1.091   1.102   1.164   1.172   1.186   1.126   1.131   1.143
344   N        -0.409  -0.465  -0.474  -0.315  -0.394  -0.399  -0.518  -0.600  -0.611
345   K        -0.409  -0.465  -0.474  -0.282  -0.373  -0.387  -0.518  -0.600  -0.611
346   N        -1.494  -1.477  -1.444  -1.201  -1.171  -1.122  -1.340  -1.313  -1.259
347   N        -0.409  -0.465  -0.474  -0.348  -0.429  -0.429  -0.518  -0.600  -0.611
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P39540
Output conservation file - output/P39540
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
