1     M         1.236   1.256   1.329   1.384   1.413   1.518   1.320   1.346   1.452
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     S        -1.503  -1.474  -1.340  -1.489  -1.445  -1.249  -1.342  -1.295  -1.108
4     L        -2.112  -2.101  -1.914  -1.949  -1.926  -1.617  -1.555  -1.527  -1.303
5     S        -1.808  -1.778  -1.640  -1.704  -1.656  -1.474  -1.449  -1.405  -1.214
6     L        -0.946  -0.865  -0.930  -1.117  -0.991  -1.077  -0.952  -0.847  -0.902
7     V        -1.505  -1.474  -1.352  -1.400  -1.360  -1.197  -1.331  -1.290  -1.117
8     S        -1.505  -1.401  -1.335  -1.497  -1.335  -1.271  -1.331  -1.215  -1.103
9     Y        -0.288  -0.365  -0.434  -0.175  -0.301  -0.440  -0.384  -0.501  -0.596
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    R        -0.288  -0.212  -0.418  -0.139  -0.034  -0.348  -0.384  -0.277  -0.574
13    L        -1.099  -1.036  -0.961  -1.268  -1.193  -1.037  -1.141  -1.064  -0.937
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    R         0.574   0.479   0.324   0.711   0.592   0.355   0.574   0.425   0.129
16    K        -0.475  -0.510  -0.452  -0.598  -0.630  -0.528  -0.703  -0.725  -0.627
17    N        -1.084  -1.023  -0.939  -1.153  -1.041  -0.923  -1.129  -1.040  -0.915
18    P        -0.056  -0.178  -0.361   0.093  -0.080  -0.406  -0.064  -0.231  -0.495
19    W        -0.969  -0.945  -0.916  -1.106  -1.076  -0.954  -1.023  -0.988  -0.895
20    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    N        -2.182  -2.115  -1.922  -2.108  -1.992  -1.743  -1.601  -1.535  -1.308
22    I        -0.969  -1.027  -0.930  -1.140  -1.182  -1.015  -1.023  -1.057  -0.908
23    F        -1.199  -1.089  -1.265  -1.246  -1.107  -1.329  -1.023  -0.903  -1.040
24    L        -0.665  -0.615  -0.484  -1.063  -0.993  -0.777  -0.916  -0.848  -0.666
25    P        -0.056  -0.224  -0.380   0.139  -0.088  -0.336  -0.064  -0.293  -0.521
26    V         0.019   0.043   0.171  -0.221  -0.183   0.019  -0.384  -0.346  -0.158
27    L        -1.834  -1.746  -1.643  -1.816  -1.679  -1.563  -1.462  -1.373  -1.216
28    A        -0.969  -0.865  -0.919  -1.246  -1.124  -1.122  -1.023  -0.911  -0.898
29    I        -0.650  -0.725  -0.885  -0.699  -0.809  -1.012  -0.597  -0.690  -0.853
30    F        -1.084  -1.034  -0.952  -1.306  -1.229  -1.076  -1.129  -1.071  -0.929
31    L        -1.808  -1.712  -1.630  -1.634  -1.501  -1.383  -1.449  -1.360  -1.208
32    I        -0.475  -0.528  -0.443  -0.567  -0.624  -0.491  -0.703  -0.748  -0.619
33    Y        -1.084  -1.116  -0.962  -1.208  -1.276  -1.041  -1.129  -1.141  -0.939
34    I        -1.808  -1.706  -1.642  -1.666  -1.510  -1.453  -1.449  -1.351  -1.216
35    I        -1.503  -1.460  -1.330  -1.579  -1.519  -1.311  -1.342  -1.288  -1.101
36    F        -0.895  -0.918  -0.930  -0.902  -0.997  -0.994  -0.916  -0.952  -0.907
37    F        -0.056  -0.083  -0.354   0.152   0.121  -0.290  -0.064  -0.103  -0.484
38    Q        -1.199  -1.178  -1.270  -0.936  -0.924  -1.030  -1.023  -0.997  -1.044
39    R        -1.486  -1.392  -1.332  -1.418  -1.289  -1.190  -1.323  -1.225  -1.101
40    D        -1.355  -1.231  -1.291  -1.222  -1.047  -1.148  -1.184  -1.047  -1.063
41    Q        -1.355  -1.285  -1.313  -1.252  -1.177  -1.185  -1.184  -1.111  -1.083
42    S        -1.486  -1.452  -1.328  -1.368  -1.315  -1.131  -1.323  -1.274  -1.099
43    L        -1.486  -1.444  -1.332  -1.615  -1.528  -1.346  -1.323  -1.268  -1.101
44    L        -0.443  -0.470  -0.432  -0.561  -0.552  -0.556  -0.627  -0.638  -0.595
45    G        -1.007  -1.043  -0.953  -1.018  -1.102  -0.954  -1.045  -1.075  -0.930
46    L        -1.099  -1.121  -0.975  -1.361  -1.395  -1.156  -1.141  -1.147  -0.951
47    N        -1.591  -1.531  -1.360  -1.654  -1.597  -1.319  -1.406  -1.337  -1.124
48    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
49    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
50    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    W        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
57    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
58    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
59    E        -1.505  -1.489  -1.350  -1.406  -1.380  -1.182  -1.331  -1.303  -1.116
60    K        -0.288  -0.203  -0.408  -0.293  -0.165  -0.487  -0.384  -0.263  -0.560
61    E        -0.946  -0.987  -0.958  -0.911  -1.002  -0.961  -0.952  -0.998  -0.933
62    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
63    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
64    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
65    Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
66    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
67    P         1.236   1.256   1.329   1.258   1.279   1.400   1.320   1.346   1.452
68    F        -1.104  -1.109  -0.974  -1.182  -1.233  -1.024  -1.134  -1.133  -0.949
69    T        -0.617  -0.626  -0.481  -0.749  -0.762  -0.547  -0.861  -0.858  -0.662
70    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
71    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
72    Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
73    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
74    M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
75    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
76    K         0.445   0.298   0.261   0.420   0.209   0.132   0.373   0.123   0.013
77    Y         0.445   0.298   0.261   0.538   0.322   0.225   0.373   0.123   0.013
78    S        -0.288  -0.395  -0.437  -0.220  -0.388  -0.467  -0.384  -0.539  -0.600
79    Y         0.445   0.298   0.261   0.546   0.334   0.243   0.373   0.123   0.013
80    K        -0.946  -0.987  -0.958  -0.942  -1.005  -0.966  -0.952  -0.998  -0.933
81    K         0.445   0.487   0.288   0.418   0.483   0.176   0.373   0.437   0.063
82    K        -0.288  -0.364  -0.433  -0.300  -0.422  -0.540  -0.384  -0.499  -0.595
83    S         1.236   1.256   1.329   1.214   1.243   1.359   1.320   1.346   1.452
84    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
85    G        -0.617  -0.600  -0.486  -0.746  -0.718  -0.545  -0.861  -0.830  -0.669
86    W         1.236   1.256   1.329   1.438   1.467   1.568   1.320   1.346   1.452
87    L        -0.617  -0.597  -0.496  -0.880  -0.833  -0.657  -0.861  -0.826  -0.682
88    F        -0.433  -0.448  -0.474  -0.406  -0.430  -0.499  -0.588  -0.606  -0.651
89    N        -0.617  -0.597  -0.496  -0.794  -0.767  -0.600  -0.861  -0.826  -0.682
90    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
91    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
92    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
93    D        -1.084  -1.108  -0.966  -1.158  -1.198  -0.988  -1.129  -1.135  -0.943
94    H        -1.693  -1.633  -1.622  -1.462  -1.398  -1.386  -1.342  -1.278  -1.200
95    V        -0.895  -0.883  -0.909  -0.832  -0.795  -0.848  -0.916  -0.885  -0.881
96    E        -1.808  -1.823  -1.651  -1.875  -1.885  -1.622  -1.449  -1.438  -1.222
97    D        -1.388  -1.446  -1.329  -1.291  -1.373  -1.214  -1.236  -1.269  -1.099
98    I        -1.808  -1.728  -1.642  -1.725  -1.598  -1.513  -1.449  -1.369  -1.216
99    I        -1.388  -1.472  -1.335  -1.412  -1.516  -1.316  -1.236  -1.287  -1.104
100   P        -0.345  -0.442  -0.446  -0.317  -0.492  -0.508  -0.490  -0.632  -0.618
101   E        -1.503  -1.474  -1.340  -1.490  -1.430  -1.230  -1.342  -1.295  -1.108
102   G        -0.475  -0.484  -0.445  -0.517  -0.501  -0.446  -0.703  -0.683  -0.617
103   H        -0.056  -0.224  -0.380   0.230   0.000  -0.278  -0.064  -0.293  -0.521
104   I        -0.345  -0.441  -0.438  -0.327  -0.462  -0.478  -0.490  -0.610  -0.608
105   A        -1.388  -1.472  -1.335  -1.397  -1.509  -1.299  -1.236  -1.287  -1.104
106   H        -0.895  -1.011  -0.933  -0.742  -0.912  -0.837  -0.916  -1.027  -0.910
107   Y         1.236   1.256   1.329   1.279   1.309   1.420   1.320   1.346   1.452
108   D         0.248   0.196   0.207   0.219   0.129   0.119   0.042  -0.059  -0.088
109   L         0.248   0.185   0.211   0.005  -0.088  -0.027   0.042  -0.079  -0.081
110   N         1.236   1.256   1.329   1.285   1.317   1.426   1.320   1.346   1.452
111   K         0.574   0.500   0.325   0.609   0.524   0.266   0.574   0.457   0.129
112   L        -0.056  -0.224  -0.380  -0.153  -0.376  -0.597  -0.064  -0.293  -0.521
113   H        -1.388  -1.279  -1.301  -1.202  -1.039  -1.086  -1.236  -1.111  -1.074
114   S        -0.969  -1.051  -0.945  -1.081  -1.185  -1.015  -1.023  -1.079  -0.923
115   T         0.074   0.067   0.177  -0.102  -0.128   0.035  -0.277  -0.299  -0.145
116   S        -0.650  -0.622  -0.874  -0.476  -0.439  -0.821  -0.597  -0.562  -0.841
117   E        -0.895  -0.789  -0.894  -0.799  -0.635  -0.791  -0.916  -0.779  -0.867
118   A         0.248   0.161   0.201   0.112  -0.044   0.015   0.042  -0.122  -0.099
119   A        -0.969  -1.053  -0.937  -1.246  -1.338  -1.136  -1.023  -1.081  -0.915
120   V        -1.388  -1.429  -1.326  -1.268  -1.330  -1.173  -1.236  -1.257  -1.097
121   N        -0.056  -0.039  -0.344   0.157   0.188  -0.262  -0.064  -0.040  -0.470
122   K        -0.475  -0.483  -0.450  -0.608  -0.610  -0.542  -0.703  -0.700  -0.626
123   E         1.236   1.256   1.329   1.213   1.245   1.358   1.320   1.346   1.452
124   H        -1.693  -1.633  -1.622  -1.421  -1.349  -1.321  -1.342  -1.278  -1.200
125   I         0.574   0.683   0.343   0.664   0.799   0.335   0.574   0.731   0.162
126   L         1.236   1.256   1.329   0.987   1.018   1.147   1.320   1.346   1.452
127   I         0.574   0.500   0.325   0.666   0.577   0.305   0.574   0.457   0.129
128   L         1.236   1.256   1.329   0.987   1.018   1.147   1.320   1.346   1.452
129   T         1.236   1.256   1.329   1.264   1.293   1.406   1.320   1.346   1.452
130   P         1.236   1.256   1.329   1.267   1.292   1.409   1.320   1.346   1.452
131   M        -0.056  -0.178  -0.361   0.203   0.032  -0.320  -0.064  -0.231  -0.495
132   Q        -0.665  -0.596  -0.487  -0.848  -0.762  -0.591  -0.916  -0.819  -0.668
133   T        -0.665  -0.596  -0.487  -0.826  -0.707  -0.558  -0.916  -0.819  -0.668
134   F         1.236   1.256   1.329   1.285   1.322   1.426   1.320   1.346   1.452
135   H        -0.665  -0.596  -0.487  -0.835  -0.715  -0.584  -0.916  -0.819  -0.668
136   Q        -0.475  -0.486  -0.447  -0.474  -0.487  -0.422  -0.703  -0.704  -0.623
137   Q        -0.475  -0.434  -0.439  -0.527  -0.482  -0.478  -0.703  -0.657  -0.614
138   Y         1.236   1.256   1.329   1.279   1.309   1.420   1.320   1.346   1.452
139   W         1.236   1.256   1.329   1.448   1.477   1.577   1.320   1.346   1.452
140   D        -0.895  -0.910  -0.913  -0.853  -0.884  -0.890  -0.916  -0.926  -0.888
141   N         1.236   1.256   1.329   1.285   1.317   1.426   1.320   1.346   1.452
142   L         0.574   0.634   0.342   0.412   0.492   0.108   0.574   0.661   0.161
143   L        -0.345  -0.283  -0.418  -0.567  -0.480  -0.638  -0.490  -0.405  -0.580
144   Q        -1.388  -1.385  -1.317  -1.333  -1.330  -1.242  -1.236  -1.211  -1.088
145   L         1.236   1.256   1.329   0.987   1.018   1.147   1.320   1.346   1.452
146   N        -0.895  -0.929  -0.928  -0.819  -0.898  -0.877  -0.916  -0.960  -0.905
147   Y         1.236   1.256   1.329   1.279   1.309   1.420   1.320   1.346   1.452
148   P        -0.056   0.060  -0.346   0.123   0.271  -0.313  -0.064   0.093  -0.473
149   R         0.019   0.043   0.171  -0.097  -0.058   0.137  -0.384  -0.346  -0.157
150   E        -1.503  -1.487  -1.334  -1.520  -1.485  -1.267  -1.342  -1.309  -1.103
151   L         1.236   1.256   1.329   0.987   1.018   1.147   1.320   1.346   1.452
152   I         0.574   0.638   0.344   0.631   0.721   0.253   0.574   0.667   0.164
153   E        -0.345  -0.436  -0.438  -0.365  -0.498  -0.517  -0.490  -0.607  -0.608
154   L         1.236   1.256   1.329   0.987   1.018   1.147   1.320   1.346   1.452
155   G         1.236   1.256   1.329   1.265   1.292   1.407   1.320   1.346   1.452
156   F         1.236   1.256   1.329   1.285   1.322   1.426   1.320   1.346   1.452
157   I         1.236   1.256   1.329   1.240   1.273   1.383   1.320   1.346   1.452
158   T        -1.503  -1.417  -1.333  -1.605  -1.493  -1.336  -1.342  -1.256  -1.104
159   P         1.236   1.256   1.329   1.267   1.292   1.409   1.320   1.346   1.452
160   R        -0.345  -0.441  -0.438  -0.325  -0.472  -0.506  -0.490  -0.610  -0.608
161   T         0.074   0.068   0.176  -0.102  -0.127   0.033  -0.277  -0.297  -0.147
162   A        -0.475  -0.441  -0.450  -0.694  -0.657  -0.615  -0.703  -0.667  -0.627
163   T        -1.388  -1.327  -1.307  -1.297  -1.208  -1.160  -1.236  -1.162  -1.079
164   G         1.236   1.256   1.329   1.265   1.292   1.407   1.320   1.346   1.452
165   D        -0.650  -0.827  -0.901  -0.439  -0.695  -0.825  -0.597  -0.803  -0.871
166   L        -1.693  -1.645  -1.614  -1.615  -1.545  -1.522  -1.342  -1.289  -1.194
167   A         0.574   0.479   0.324   0.565   0.440   0.214   0.574   0.425   0.129
168   L        -0.056  -0.224  -0.380  -0.125  -0.337  -0.533  -0.064  -0.293  -0.521
169   K        -1.388  -1.468  -1.320  -1.288  -1.387  -1.179  -1.236  -1.283  -1.092
170   K        -0.665  -0.607  -0.496  -0.853  -0.762  -0.587  -0.916  -0.836  -0.681
171   L         1.236   1.256   1.329   0.987   1.018   1.147   1.320   1.346   1.452
172   E        -0.650  -0.827  -0.901  -0.450  -0.690  -0.811  -0.597  -0.803  -0.871
173   N        -1.388  -1.386  -1.302  -1.307  -1.292  -1.200  -1.236  -1.211  -1.076
174   A        -0.056  -0.065  -0.356   0.040   0.023  -0.343  -0.064  -0.080  -0.487
175   I        -0.475  -0.439  -0.441  -0.628  -0.584  -0.589  -0.703  -0.664  -0.617
176   K        -0.895  -0.947  -0.930  -0.924  -1.023  -0.968  -0.916  -0.977  -0.907
177   K        -0.650  -0.637  -0.866  -0.532  -0.525  -0.873  -0.597  -0.582  -0.831
178   V        -0.969  -0.971  -0.931  -0.991  -0.989  -0.927  -1.023  -1.009  -0.909
179   Q         0.574   0.634   0.342   0.761   0.841   0.406   0.574   0.661   0.161
180   T        -0.969  -0.865  -0.928  -1.008  -0.868  -0.922  -1.023  -0.902  -0.905
181   D        -1.388  -1.324  -1.302  -1.253  -1.142  -1.122  -1.236  -1.155  -1.075
182   K        -0.056  -0.224  -0.380   0.046  -0.174  -0.417  -0.064  -0.293  -0.521
183   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
184   K        -1.104  -1.126  -0.976  -1.156  -1.195  -0.966  -1.134  -1.150  -0.951
185   T        -1.505  -1.440  -1.331  -1.441  -1.353  -1.201  -1.331  -1.256  -1.099
186   Q        -1.808  -1.746  -1.632  -1.749  -1.667  -1.503  -1.449  -1.385  -1.209
187   R        -0.345  -0.283  -0.418  -0.312  -0.224  -0.442  -0.490  -0.405  -0.580
188   F         1.236   1.256   1.329   1.285   1.322   1.426   1.320   1.346   1.452
189   S        -1.084  -1.039  -0.957  -1.243  -1.187  -1.042  -1.129  -1.074  -0.935
190   K        -0.056  -0.224  -0.380   0.034  -0.190  -0.446  -0.064  -0.293  -0.521
191   I         0.074   0.068   0.176  -0.110  -0.130   0.031  -0.277  -0.297  -0.147
192   T        -0.056  -0.224  -0.380   0.114  -0.117  -0.389  -0.064  -0.293  -0.521
193   I         1.236   1.256   1.329   1.240   1.273   1.383   1.320   1.346   1.452
194   L         1.236   1.256   1.329   0.987   1.018   1.147   1.320   1.346   1.452
195   R         0.574   0.479   0.324   0.705   0.584   0.339   0.574   0.425   0.129
196   Q         1.236   1.256   1.329   1.344   1.375   1.481   1.320   1.346   1.452
197   N        -0.650  -0.539  -0.853  -0.465  -0.317  -0.795  -0.597  -0.461  -0.817
198   S        -0.056  -0.160  -0.367   0.066  -0.071  -0.405  -0.064  -0.205  -0.503
199   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
200   Q        -1.808  -1.743  -1.642  -1.585  -1.503  -1.366  -1.449  -1.378  -1.216
201   S        -1.199  -1.314  -1.303  -1.079  -1.290  -1.308  -1.023  -1.133  -1.075
202   F        -0.969  -1.051  -0.945  -1.137  -1.239  -1.068  -1.023  -1.079  -0.923
203   D        -1.693  -1.741  -1.642  -1.476  -1.571  -1.438  -1.342  -1.370  -1.215
204   K        -0.895  -0.859  -0.915  -0.877  -0.809  -0.898  -0.916  -0.857  -0.889
205   L        -0.475  -0.446  -0.439  -0.614  -0.513  -0.499  -0.703  -0.639  -0.608
206   M        -2.112  -1.997  -1.903  -1.883  -1.728  -1.597  -1.555  -1.452  -1.296
207   E         1.236   1.256   1.329   1.213   1.245   1.358   1.320   1.346   1.452
208   K        -0.056  -0.224  -0.380   0.016  -0.216  -0.486  -0.064  -0.293  -0.521
209   E         0.074   0.110   0.185  -0.132  -0.069   0.030  -0.277  -0.217  -0.130
210   R         1.236   1.256   1.329   1.279   1.307   1.420   1.320   1.346   1.452
211   H         1.236   1.256   1.329   1.371   1.401   1.505   1.320   1.346   1.452
212   A         0.248   0.161   0.201   0.082  -0.080  -0.035   0.042  -0.122  -0.099
213   L        -0.590  -0.633  -0.500  -0.837  -0.873  -0.648  -0.810  -0.864  -0.686
214   D        -1.503  -1.408  -1.332  -1.597  -1.470  -1.331  -1.342  -1.250  -1.102
215   V        -0.056  -0.224  -0.380   0.090  -0.143  -0.407  -0.064  -0.293  -0.521
216   Q         1.236   1.256   1.329   1.344   1.375   1.481   1.320   1.346   1.452
217   K         1.236   1.256   1.329   1.177   1.210   1.324   1.320   1.346   1.452
218   E         0.248   0.196   0.207   0.142   0.041   0.017   0.042  -0.059  -0.088
219   R         1.236   1.256   1.329   1.279   1.307   1.420   1.320   1.346   1.452
220   R         1.236   1.256   1.329   1.279   1.307   1.420   1.320   1.346   1.452
221   A        -0.475  -0.526  -0.447  -0.654  -0.714  -0.583  -0.703  -0.744  -0.623
222   A        -0.345  -0.369  -0.417  -0.385  -0.415  -0.485  -0.490  -0.500  -0.575
223   M         0.574   0.479   0.324   0.775   0.643   0.345   0.574   0.425   0.129
224   A         0.574   0.552   0.336   0.561   0.532   0.225   0.574   0.538   0.150
225   L        -0.056  -0.224  -0.380  -0.182  -0.417  -0.664  -0.064  -0.293  -0.521
226   A         0.574   0.479   0.324   0.568   0.445   0.224   0.574   0.425   0.129
227   R         1.236   1.256   1.329   1.279   1.307   1.420   1.320   1.346   1.452
228   N         1.236   1.256   1.329   1.285   1.317   1.426   1.320   1.346   1.452
229   E        -0.475  -0.499  -0.446  -0.608  -0.610  -0.529  -0.703  -0.700  -0.618
230   L         1.236   1.256   1.329   0.987   1.018   1.147   1.320   1.346   1.452
231   L        -0.345  -0.309  -0.407  -0.567  -0.498  -0.620  -0.490  -0.423  -0.561
232   F         0.248   0.185   0.211   0.166   0.038   0.007   0.042  -0.079  -0.081
233   S         0.248   0.247   0.213   0.184   0.178   0.094   0.042   0.033  -0.078
234   T         1.236   1.256   1.329   1.264   1.293   1.406   1.320   1.346   1.452
235   I         0.248   0.161   0.201   0.121  -0.059  -0.055   0.042  -0.122  -0.099
236   G        -0.650  -0.638  -0.876  -0.493  -0.485  -0.910  -0.597  -0.584  -0.842
237   P         1.236   1.256   1.329   1.267   1.292   1.409   1.320   1.346   1.452
238   H        -0.665  -0.658  -0.503  -0.767  -0.768  -0.538  -0.916  -0.898  -0.689
239   T         1.236   1.256   1.329   1.264   1.293   1.406   1.320   1.346   1.452
240   S         0.574   0.552   0.336   0.626   0.600   0.267   0.574   0.538   0.150
241   W         1.236   1.256   1.329   1.448   1.477   1.577   1.320   1.346   1.452
242   V        -0.345  -0.264  -0.410  -0.286  -0.182  -0.358  -0.490  -0.384  -0.570
243   L         1.236   1.256   1.329   0.987   1.018   1.147   1.320   1.346   1.452
244   W         1.236   1.256   1.329   1.448   1.477   1.577   1.320   1.346   1.452
245   L         1.236   1.256   1.329   0.987   1.018   1.147   1.320   1.346   1.452
246   D         1.236   1.256   1.329   1.243   1.273   1.387   1.320   1.346   1.452
247   A         0.248   0.185   0.211   0.094  -0.023   0.003   0.042  -0.079  -0.081
248   D         1.236   1.256   1.329   1.243   1.273   1.387   1.320   1.346   1.452
249   I         0.574   0.552   0.336   0.666   0.645   0.324   0.574   0.538   0.150
250   I         0.019   0.044   0.171  -0.221  -0.180   0.020  -0.384  -0.344  -0.157
251   E         1.236   1.256   1.329   1.213   1.245   1.358   1.320   1.346   1.452
252   T         1.236   1.256   1.329   1.264   1.293   1.406   1.320   1.346   1.452
253   P         0.574   0.638   0.344   0.684   0.764   0.341   0.574   0.667   0.164
254   P        -0.895  -0.945  -0.913  -0.792  -0.853  -0.817  -0.916  -0.949  -0.888
255   S         0.248   0.347   0.256   0.216   0.371   0.192   0.042   0.207   0.003
256   L         0.574   0.655   0.342   0.412   0.516   0.108   0.574   0.691   0.161
257   I         0.574   0.658   0.342   0.631   0.745   0.250   0.574   0.695   0.161
258   Q         1.236   1.256   1.329   1.344   1.375   1.481   1.320   1.346   1.452
259   D         1.236   1.256   1.329   1.243   1.273   1.387   1.320   1.346   1.452
260   M         0.074   0.119   0.192  -0.252  -0.185  -0.049  -0.277  -0.200  -0.118
261   T        -0.345  -0.360  -0.436  -0.349  -0.427  -0.525  -0.490  -0.541  -0.605
262   K        -1.388  -1.371  -1.302  -1.382  -1.356  -1.263  -1.236  -1.204  -1.077
263   H         0.574   0.638   0.344   0.762   0.850   0.372   0.574   0.667   0.164
264   N        -0.056  -0.160  -0.367   0.142   0.005  -0.334  -0.064  -0.205  -0.503
265   K         0.574   0.479   0.324   0.599   0.483   0.239   0.574   0.425   0.129
266   A        -0.345  -0.321  -0.422  -0.326  -0.329  -0.476  -0.490  -0.488  -0.586
267   I        -0.056  -0.042  -0.354   0.058   0.061  -0.432  -0.064  -0.051  -0.485
268   L        -0.345  -0.352  -0.416  -0.571  -0.563  -0.642  -0.490  -0.479  -0.573
269   A        -0.665  -0.596  -0.487  -0.922  -0.800  -0.638  -0.916  -0.819  -0.668
270   A         0.574   0.500   0.325   0.569   0.472   0.226   0.574   0.457   0.129
271   N         1.236   1.256   1.329   1.285   1.317   1.426   1.320   1.346   1.452
272   I        -0.475  -0.409  -0.448  -0.418  -0.318  -0.347  -0.703  -0.638  -0.625
273   Y        -0.345  -0.379  -0.437  -0.255  -0.334  -0.390  -0.490  -0.562  -0.607
274   Q         1.236   1.256   1.329   1.344   1.375   1.481   1.320   1.346   1.452
275   R         0.248   0.233   0.207   0.218   0.186   0.090   0.042   0.009  -0.088
276   F        -0.345  -0.417  -0.426  -0.257  -0.341  -0.379  -0.490  -0.573  -0.590
277   Y        -1.388  -1.376  -1.310  -1.233  -1.215  -1.123  -1.236  -1.209  -1.084
278   D         0.074   0.072   0.176  -0.082  -0.093   0.062  -0.277  -0.290  -0.147
279   E        -1.808  -1.782  -1.638  -1.716  -1.691  -1.465  -1.449  -1.408  -1.213
280   E        -1.486  -1.451  -1.329  -1.439  -1.379  -1.208  -1.323  -1.275  -1.099
281   K        -1.486  -1.452  -1.334  -1.435  -1.390  -1.207  -1.323  -1.276  -1.103
282   K         0.516   0.579   0.311   0.531   0.619   0.240   0.485   0.578   0.106
283   Q        -0.540  -0.605  -0.475  -0.634  -0.744  -0.569  -0.763  -0.829  -0.654
284   P        -0.790  -0.777  -0.906  -0.627  -0.615  -0.834  -0.766  -0.753  -0.876
285   S        -0.528  -0.446  -0.458  -0.686  -0.559  -0.574  -0.766  -0.658  -0.635
286   I        -0.650  -0.827  -0.901  -0.507  -0.782  -0.956  -0.597  -0.803  -0.871
287   R         0.574   0.479   0.324   0.708   0.588   0.347   0.574   0.425   0.129
288   P         1.236   1.256   1.329   1.267   1.292   1.409   1.320   1.346   1.452
289   Y         1.236   1.256   1.329   1.279   1.309   1.420   1.320   1.346   1.452
290   D         1.236   1.256   1.329   1.243   1.273   1.387   1.320   1.346   1.452
291   F         0.574   0.552   0.336   0.717   0.701   0.378   0.574   0.538   0.150
292   N         1.236   1.256   1.329   1.285   1.317   1.426   1.320   1.346   1.452
293   N         0.248   0.185   0.211   0.237   0.123   0.123   0.042  -0.079  -0.081
294   W         1.236   1.256   1.329   1.448   1.477   1.577   1.320   1.346   1.452
295   Q        -0.590  -0.534  -0.482  -0.704  -0.611  -0.553  -0.810  -0.729  -0.662
296   E         0.074   0.059   0.172  -0.132  -0.168   0.006  -0.277  -0.315  -0.155
297   S         1.236   1.256   1.329   1.214   1.244   1.360   1.320   1.346   1.452
298   D        -0.969  -0.937  -0.924  -0.920  -0.861  -0.829  -1.023  -0.976  -0.902
299   T        -0.895  -0.834  -0.893  -0.801  -0.696  -0.794  -0.916  -0.829  -0.865
300   G         0.074   0.059   0.172  -0.140  -0.197  -0.024  -0.277  -0.315  -0.155
301   L        -0.475  -0.495  -0.447  -0.716  -0.705  -0.598  -0.703  -0.719  -0.623
302   E        -0.475  -0.397  -0.436  -0.615  -0.504  -0.515  -0.703  -0.604  -0.610
303   I        -0.345  -0.284  -0.405  -0.546  -0.435  -0.582  -0.490  -0.384  -0.561
304   A         0.574   0.638   0.344   0.568   0.645   0.257   0.574   0.667   0.164
305   S        -1.388  -1.301  -1.299  -1.351  -1.218  -1.200  -1.236  -1.134  -1.072
306   Q        -1.503  -1.482  -1.333  -1.417  -1.383  -1.162  -1.342  -1.305  -1.103
307   M         0.074   0.145   0.196  -0.111   0.038   0.047  -0.277  -0.152  -0.110
308   G        -1.199  -1.213  -1.287  -0.972  -1.004  -1.148  -1.023  -1.031  -1.060
309   D        -1.199  -1.301  -1.301  -0.985  -1.146  -1.174  -1.023  -1.121  -1.073
310   D         0.574   0.655   0.342   0.676   0.778   0.354   0.574   0.691   0.161
311   E         0.248   0.196   0.207   0.176   0.085   0.072   0.042  -0.059  -0.088
312   I         1.236   1.256   1.329   1.240   1.273   1.383   1.320   1.346   1.452
313   I        -0.345  -0.360  -0.436  -0.428  -0.517  -0.624  -0.490  -0.541  -0.605
314   V         0.074   0.049   0.172  -0.244  -0.339  -0.146  -0.277  -0.335  -0.156
315   E         1.236   1.256   1.329   1.213   1.245   1.358   1.320   1.346   1.452
316   G         1.236   1.256   1.329   1.265   1.292   1.407   1.320   1.346   1.452
317   Y         1.236   1.256   1.329   1.279   1.309   1.420   1.320   1.346   1.452
318   A        -0.345  -0.311  -0.409  -0.435  -0.373  -0.524  -0.490  -0.425  -0.567
319   E         0.574   0.500   0.325   0.639   0.550   0.283   0.574   0.457   0.129
320   I        -0.475  -0.499  -0.446  -0.507  -0.521  -0.488  -0.703  -0.700  -0.618
321   A        -0.056  -0.105  -0.357   0.004  -0.068  -0.421  -0.064  -0.135  -0.488
322   T         1.236   1.256   1.329   1.264   1.293   1.406   1.320   1.346   1.452
323   Y         0.574   0.634   0.342   0.723   0.800   0.414   0.574   0.661   0.161
324   R         1.236   1.256   1.329   1.279   1.307   1.420   1.320   1.346   1.452
325   P        -0.895  -0.995  -0.932  -0.883  -1.047  -0.981  -0.916  -1.015  -0.909
326   L         1.236   1.256   1.329   0.987   1.018   1.147   1.320   1.346   1.452
327   M         1.236   1.256   1.329   1.384   1.413   1.518   1.320   1.346   1.452
328   A         1.236   1.256   1.329   1.139   1.163   1.289   1.320   1.346   1.452
329   H        -0.345  -0.464  -0.446  -0.227  -0.423  -0.429  -0.490  -0.651  -0.618
330   F        -0.345  -0.464  -0.446  -0.264  -0.438  -0.419  -0.490  -0.651  -0.618
331   Y         1.236   1.256   1.329   1.279   1.309   1.420   1.320   1.346   1.452
332   D        -0.969  -0.932  -0.920  -0.983  -0.922  -0.879  -1.023  -0.966  -0.898
333   A        -0.345  -0.378  -0.418  -0.424  -0.465  -0.531  -0.490  -0.515  -0.580
334   N        -1.388  -1.420  -1.312  -1.244  -1.267  -1.127  -1.236  -1.241  -1.084
335   G        -0.056  -0.224  -0.380   0.099  -0.142  -0.426  -0.064  -0.293  -0.521
336   V        -0.650  -0.465  -0.859  -0.463  -0.216  -0.803  -0.597  -0.368  -0.824
337   P        -0.895  -0.829  -0.911  -0.801  -0.742  -0.829  -0.916  -0.856  -0.887
338   G        -1.084  -1.043  -0.960  -1.040  -0.996  -0.857  -1.129  -1.089  -0.938
339   E        -0.475  -0.393  -0.440  -0.578  -0.456  -0.505  -0.703  -0.596  -0.612
340   E        -0.345  -0.368  -0.413  -0.455  -0.456  -0.586  -0.490  -0.499  -0.571
341   M        -0.056  -0.160  -0.367   0.242   0.103  -0.246  -0.064  -0.205  -0.503
342   A        -1.199  -1.141  -1.264  -1.081  -1.007  -1.187  -1.023  -0.954  -1.039
343   L         1.236   1.256   1.329   0.987   1.018   1.147   1.320   1.346   1.452
344   D         1.236   1.256   1.329   1.243   1.273   1.387   1.320   1.346   1.452
345   G         1.236   1.256   1.329   1.265   1.292   1.407   1.320   1.346   1.452
346   V         1.236   1.256   1.329   1.238   1.267   1.382   1.320   1.346   1.452
347   G         1.236   1.256   1.329   1.265   1.292   1.407   1.320   1.346   1.452
348   G         0.574   0.479   0.324   0.695   0.574   0.336   0.574   0.425   0.129
349   G         0.074   0.049   0.172  -0.075  -0.137   0.056  -0.277  -0.335  -0.156
350   C         0.074   0.155   0.206  -0.058   0.052   0.149  -0.277  -0.134  -0.091
351   T        -0.665  -0.596  -0.487  -0.996  -0.918  -0.729  -0.916  -0.819  -0.668
352   L         0.574   0.634   0.342   0.435   0.511   0.161   0.574   0.661   0.161
353   V         1.236   1.256   1.329   1.238   1.267   1.382   1.320   1.346   1.452
354   K         1.236   1.256   1.329   1.177   1.210   1.324   1.320   1.346   1.452
355   A         0.574   0.552   0.336   0.561   0.532   0.225   0.574   0.538   0.150
356   E        -0.345  -0.369  -0.417  -0.363  -0.378  -0.479  -0.490  -0.500  -0.575
357   V         1.236   1.256   1.329   1.238   1.267   1.382   1.320   1.346   1.452
358   H         1.236   1.256   1.329   1.371   1.401   1.505   1.320   1.346   1.452
359   R         1.236   1.256   1.329   1.279   1.307   1.420   1.320   1.346   1.452
360   D         1.236   1.256   1.329   1.243   1.273   1.387   1.320   1.346   1.452
361   G         1.236   1.256   1.329   1.265   1.292   1.407   1.320   1.346   1.452
362   A         1.236   1.256   1.329   1.139   1.163   1.289   1.320   1.346   1.452
363   M         0.574   0.479   0.324   0.775   0.643   0.345   0.574   0.425   0.129
364   F         1.236   1.256   1.329   1.285   1.322   1.426   1.320   1.346   1.452
365   P         0.574   0.655   0.342   0.696   0.794   0.367   0.574   0.691   0.161
366   N        -1.503  -1.511  -1.338  -1.469  -1.479  -1.230  -1.342  -1.323  -1.107
367   F         1.236   1.256   1.329   1.285   1.322   1.426   1.320   1.346   1.452
368   P         1.236   1.256   1.329   1.267   1.292   1.409   1.320   1.346   1.452
369   F         1.236   1.256   1.329   1.285   1.322   1.426   1.320   1.346   1.452
370   Y         1.236   1.256   1.329   1.279   1.309   1.420   1.320   1.346   1.452
371   H         0.574   0.552   0.336   0.802   0.781   0.455   0.574   0.538   0.150
372   L         1.236   1.256   1.329   0.987   1.018   1.147   1.320   1.346   1.452
373   I         1.236   1.256   1.329   1.240   1.273   1.383   1.320   1.346   1.452
374   E         1.236   1.256   1.329   1.213   1.245   1.358   1.320   1.346   1.452
375   T         0.574   0.479   0.324   0.686   0.565   0.317   0.574   0.425   0.129
376   E         1.236   1.256   1.329   1.213   1.245   1.358   1.320   1.346   1.452
377   G         0.574   0.655   0.342   0.677   0.779   0.323   0.574   0.691   0.161
378   F         1.236   1.256   1.329   1.285   1.322   1.426   1.320   1.346   1.452
379   A         1.236   1.256   1.329   1.139   1.163   1.289   1.320   1.346   1.452
380   K         1.236   1.256   1.329   1.177   1.210   1.324   1.320   1.346   1.452
381   M         1.236   1.256   1.329   1.384   1.413   1.518   1.320   1.346   1.452
382   A         1.236   1.256   1.329   1.139   1.163   1.289   1.320   1.346   1.452
383   K         1.236   1.256   1.329   1.177   1.210   1.324   1.320   1.346   1.452
384   R         1.236   1.256   1.329   1.279   1.307   1.420   1.320   1.346   1.452
385   L         1.236   1.256   1.329   0.987   1.018   1.147   1.320   1.346   1.452
386   N         0.248   0.347   0.256   0.240   0.390   0.225   0.042   0.207   0.003
387   Y        -0.056  -0.224  -0.380   0.195  -0.012  -0.228  -0.064  -0.293  -0.521
388   D        -1.693  -1.716  -1.629  -1.484  -1.521  -1.413  -1.342  -1.352  -1.206
389   V        -0.056  -0.160  -0.367   0.087  -0.058  -0.392  -0.064  -0.205  -0.503
390   F        -0.475  -0.526  -0.451  -0.510  -0.570  -0.454  -0.703  -0.751  -0.628
391   G         1.236   1.256   1.329   1.265   1.292   1.407   1.320   1.346   1.452
392   L         1.236   1.256   1.329   0.987   1.018   1.147   1.320   1.346   1.452
393   P         1.236   1.256   1.329   1.267   1.292   1.409   1.320   1.346   1.452
394   N         0.574   0.479   0.324   0.717   0.602   0.359   0.574   0.425   0.129
395   Y         1.236   1.256   1.329   1.279   1.309   1.420   1.320   1.346   1.452
396   L         0.574   0.500   0.325   0.403   0.311   0.056   0.574   0.457   0.129
397   V         1.236   1.256   1.329   1.238   1.267   1.382   1.320   1.346   1.452
398   Y         0.074   0.085   0.178  -0.051  -0.035   0.091  -0.277  -0.265  -0.144
399   H         1.236   1.256   1.329   1.371   1.401   1.505   1.320   1.346   1.452
400   I        -0.475  -0.499  -0.446  -0.517  -0.510  -0.428  -0.703  -0.700  -0.618
401   E        -0.475  -0.365  -0.431  -0.554  -0.373  -0.458  -0.703  -0.549  -0.598
402   E         1.236   1.256   1.329   1.213   1.245   1.358   1.320   1.346   1.452
403   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
404   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
405   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P39107
Output conservation file - output/P39107
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
