1     M         2.049   2.074   2.180   2.405   2.440   2.604   2.340   2.378   2.577
2     S         2.049   2.074   2.180   1.979   2.012   2.175   2.340   2.378   2.577
3     -         0.666   0.726   0.803   0.763   0.856   0.969   0.281   0.390   0.486
4     -        -0.087   0.019  -0.014  -0.457  -0.314  -0.343  -0.342  -0.183  -0.251
5     -         0.666   0.726   0.803   0.472   0.567   0.676   0.281   0.390   0.486
6     -         2.049   2.074   2.180   1.781   1.822   1.976   2.340   2.378   2.577
7     N         2.049   2.074   2.180   2.071   2.111   2.268   2.340   2.378   2.577
8     P         0.820   0.900   0.892   0.905   1.027   1.002   0.589   0.733   0.670
9     F         0.646   0.672   0.769   0.850   0.893   1.034   0.238   0.279   0.414
10    D         0.413   0.400   0.231   0.683   0.667   0.456   0.414   0.393   0.128
11    L         1.206   1.169   1.068   1.494   1.456   1.352   1.289   1.222   1.018
12    L         2.049   2.074   2.180   2.176   2.209   2.373   2.340   2.378   2.577
13    G         2.049   2.074   2.180   2.032   2.072   2.229   2.340   2.378   2.577
14    N         1.206   1.109   1.060   1.322   1.197   1.118   1.289   1.117   1.003
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    D         2.049   2.074   2.180   2.081   2.122   2.278   2.340   2.378   2.577
32    V         1.206   1.109   1.060   1.419   1.280   1.192   1.289   1.117   1.003
33    E         1.206   1.109   1.060   1.170   1.029   0.945   1.289   1.117   1.003
34    D         0.086   0.019   0.054   0.077  -0.013   0.012  -0.112  -0.195  -0.162
35    A        -0.981  -0.984  -1.030  -0.795  -0.797  -0.910  -0.812  -0.813  -0.838
36    D        -1.134  -1.076  -1.062  -1.021  -0.925  -0.906  -0.988  -0.928  -0.877
37    V        -0.981  -1.021  -1.008  -0.973  -1.040  -0.979  -0.812  -0.853  -0.816
38    V        -0.321  -0.264  -0.450  -0.114  -0.042  -0.357  -0.287  -0.212  -0.445
39    V        -1.541  -1.519  -1.461  -1.275  -1.242  -1.173  -1.163  -1.136  -1.048
40    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    L        -0.574  -0.651  -0.580  -0.444  -0.522  -0.435  -0.637  -0.711  -0.619
42    P         0.413   0.425   0.229   0.651   0.667   0.370   0.414   0.428   0.124
43    P        -1.541  -1.515  -1.459  -1.199  -1.177  -1.084  -1.163  -1.133  -1.047
44    K         0.086   0.053   0.083  -0.181  -0.216  -0.181  -0.112  -0.139  -0.110
45    E         0.413   0.306   0.194   0.586   0.452   0.338   0.414   0.251   0.071
46    I         0.413   0.433   0.233   0.826   0.849   0.616   0.414   0.440   0.131
47    V        -0.321  -0.455  -0.511  -0.024  -0.249  -0.368  -0.287  -0.456  -0.522
48    K         1.206   1.109   1.060   1.087   0.980   0.929   1.289   1.117   1.003
49    S        -0.727  -0.718  -0.634  -0.900  -0.852  -0.739  -0.812  -0.793  -0.681
50    N        -0.167  -0.137  -0.062  -0.275  -0.222  -0.115  -0.462  -0.419  -0.324
51    T         1.206   1.169   1.068   1.429   1.383   1.247   1.289   1.222   1.018
52    S         1.206   1.205   1.074   1.307   1.312   1.183   1.289   1.283   1.029
53    S         0.413   0.306   0.194   0.553   0.405   0.259   0.414   0.251   0.071
54    K         1.206   1.205   1.074   1.072   1.081   0.920   1.289   1.283   1.029
55    K         1.206   1.109   1.060   1.050   0.930   0.862   1.289   1.117   1.003
56    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
57    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
58    A        -0.028  -0.075  -0.001  -0.301  -0.339  -0.245  -0.282  -0.330  -0.238
59    D         0.820   0.755   0.813   0.794   0.684   0.746   0.589   0.449   0.507
60    V        -0.574  -0.638  -0.580  -0.505  -0.585  -0.523  -0.637  -0.700  -0.619
61    P         0.086   0.092   0.065   0.063   0.071   0.011  -0.112  -0.098  -0.145
62    P         0.413   0.306   0.194   0.645   0.489   0.303   0.414   0.251   0.071
63    P         0.086   0.100   0.088  -0.033   0.007  -0.057  -0.112  -0.075  -0.103
64    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
65    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
66    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
67    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
68    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
69    S         0.413   0.274   0.187   0.541   0.358   0.229   0.414   0.205   0.060
70    A         0.086   0.010   0.025  -0.315  -0.446  -0.413  -0.112  -0.227  -0.206
71    D        -0.321  -0.455  -0.511  -0.205  -0.426  -0.585  -0.287  -0.456  -0.522
72    P         0.820   0.755   0.813   0.716   0.558   0.611   0.589   0.449   0.507
73    S         0.413   0.379   0.220   0.272   0.223   0.007   0.414   0.355   0.112
74    K         0.086   0.010   0.025   0.022  -0.048   0.016  -0.112  -0.227  -0.206
75    A         0.086  -0.014   0.026  -0.190  -0.322  -0.249  -0.112  -0.251  -0.204
76    R        -0.574  -0.584  -0.571  -0.778  -0.782  -0.797  -0.637  -0.633  -0.603
77    K        -0.321  -0.455  -0.511  -0.381  -0.567  -0.662  -0.287  -0.456  -0.522
78    N        -0.118  -0.113  -0.038  -0.354  -0.343  -0.252  -0.406  -0.393  -0.292
79    R         0.646   0.653   0.753   0.215   0.225   0.380   0.238   0.239   0.382
80    P        -1.541  -1.484  -1.469  -1.480  -1.347  -1.383  -1.163  -1.106  -1.055
81    R        -1.134  -1.104  -1.072  -1.322  -1.278  -1.241  -0.988  -0.953  -0.887
82    P        -0.028   0.002   0.018  -0.034   0.005   0.014  -0.282  -0.240  -0.217
83    S        -0.028  -0.075  -0.001   0.025  -0.012   0.088  -0.282  -0.330  -0.238
84    G         2.049   2.074   2.180   2.040   2.077   2.236   2.340   2.378   2.577
85    N         2.049   2.074   2.180   2.053   2.095   2.250   2.340   2.378   2.577
86    E         2.049   2.074   2.180   1.939   1.966   2.135   2.340   2.378   2.577
87    G         0.625   0.651   0.755   0.155   0.173   0.333   0.195   0.235   0.385
88    A         1.123   1.002   0.994   0.942   0.786   0.800   1.148   0.924   0.875
89    I        -0.682  -0.686  -0.623  -0.353  -0.401  -0.290  -0.759  -0.758  -0.664
90    R         0.741   0.805   0.847   0.503   0.615   0.646   0.433   0.548   0.578
91    D        -0.028  -0.081   0.005  -0.089  -0.157  -0.047  -0.282  -0.341  -0.229
92    K        -0.028  -0.109  -0.011  -0.307  -0.406  -0.262  -0.282  -0.386  -0.259
93    T        -0.687  -0.657  -0.605  -0.708  -0.653  -0.574  -0.749  -0.709  -0.639
94    A         0.097   0.030   0.051  -0.177  -0.290  -0.249  -0.063  -0.166  -0.151
95    G         0.097   0.030   0.051   0.072  -0.053  -0.039  -0.063  -0.166  -0.151
96    R         1.021   1.035   0.975   0.995   1.010   0.916   0.967   0.985   0.838
97    R         0.097   0.112   0.088   0.047   0.058  -0.015  -0.063  -0.045  -0.094
98    N         0.097   0.081   0.059   0.182   0.171   0.119  -0.063  -0.088  -0.139
99    N         1.206   1.252   1.086   1.353   1.418   1.211   1.289   1.361   1.052
100   R        -0.321  -0.315  -0.450  -0.101  -0.134  -0.296  -0.287  -0.282  -0.445
101   S        -0.727  -0.720  -0.632  -0.979  -0.975  -0.847  -0.812  -0.795  -0.677
102   K         0.413   0.370   0.213   0.409   0.376   0.182   0.414   0.343   0.101
103   D        -0.574  -0.604  -0.586  -0.446  -0.492  -0.460  -0.637  -0.672  -0.626
104   V         0.820   0.799   0.827   0.933   0.893   0.918   0.589   0.537   0.537
105   T        -1.541  -1.484  -1.469  -1.487  -1.378  -1.385  -1.163  -1.106  -1.055
106   D        -1.134  -1.084  -1.062  -1.215  -1.171  -1.112  -0.988  -0.934  -0.878
107   S        -1.134  -1.190  -1.106  -0.888  -0.941  -0.810  -0.988  -1.026  -0.916
108   A        -0.321  -0.315  -0.450  -0.379  -0.383  -0.541  -0.287  -0.282  -0.445
109   T        -0.727  -0.725  -0.643  -0.944  -0.974  -0.841  -0.812  -0.797  -0.688
110   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
111   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
112   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
113   T        -0.981  -1.053  -1.040  -0.834  -0.974  -1.018  -0.812  -0.885  -0.848
114   K        -1.541  -1.519  -1.461  -1.624  -1.558  -1.499  -1.163  -1.136  -1.048
115   K        -1.134  -1.052  -1.063  -1.091  -0.969  -0.988  -0.988  -0.907  -0.879
116   S        -0.981  -0.984  -1.030  -1.124  -1.129  -1.223  -0.812  -0.813  -0.838
117   N         0.086   0.100   0.088   0.292   0.322   0.318  -0.112  -0.075  -0.103
118   T        -0.981  -0.825  -0.997  -0.901  -0.699  -0.878  -0.812  -0.633  -0.803
119   R         0.820   0.896   0.900   0.650   0.776   0.745   0.589   0.726   0.686
120   R        -0.981  -1.048  -1.040  -1.046  -1.162  -1.134  -0.812  -0.880  -0.849
121   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
122   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
123   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
124   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
125   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
126   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
127   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
128   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
129   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
130   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
131   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
132   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
133   A        -1.541  -1.557  -1.493  -1.276  -1.330  -1.227  -1.163  -1.168  -1.075
134   T        -0.574  -0.582  -0.572  -0.203  -0.196  -0.189  -0.637  -0.631  -0.605
135   D         2.049   2.074   2.180   2.083   2.121   2.279   2.340   2.378   2.577
136   R         2.049   2.074   2.180   2.044   2.068   2.241   2.340   2.378   2.577
137   H         1.206   1.169   1.068   1.662   1.616   1.476   1.289   1.222   1.018
138   S         2.049   2.074   2.180   1.979   2.012   2.175   2.340   2.378   2.577
139   R         0.086   0.026   0.025   0.124   0.029   0.021  -0.112  -0.212  -0.207
140   T         0.820   0.840   0.837   0.838   0.864   0.819   0.589   0.617   0.557
141   G         0.413   0.432   0.234   0.650   0.690   0.438   0.414   0.442   0.133
142   K         0.413   0.306   0.194   0.351   0.210   0.061   0.414   0.251   0.071
143   T        -0.014  -0.062   0.020  -0.024  -0.080   0.052  -0.287  -0.333  -0.219
144   D         1.206   1.205   1.074   1.348   1.356   1.176   1.289   1.283   1.029
145   T         0.086   0.095   0.068   0.080   0.089   0.061  -0.112  -0.109  -0.144
146   K        -0.321  -0.329  -0.460  -0.412  -0.433  -0.632  -0.287  -0.295  -0.458
147   K         1.206   1.252   1.086   1.050   1.115   0.901   1.289   1.361   1.052
148   K         0.267   0.198   0.133   0.129   0.017  -0.085   0.195   0.089  -0.025
149   V        -1.157  -1.150  -1.079  -0.819  -0.819  -0.707  -0.997  -0.984  -0.888
150   N        -1.157  -1.194  -1.114  -1.110  -1.179  -1.075  -0.997  -1.026  -0.922
151   Q        -0.503  -0.583  -0.576  -0.229  -0.370  -0.391  -0.521  -0.617  -0.603
152   G         0.267   0.334   0.177   0.290   0.402   0.117   0.195   0.294   0.044
153   W         1.206   1.252   1.086   1.714   1.775   1.585   1.289   1.361   1.052
154   G         1.206   1.252   1.086   1.257   1.328   1.076   1.289   1.361   1.052
155   D         0.413   0.486   0.247   0.613   0.706   0.371   0.414   0.519   0.153
156   D        -1.157  -1.124  -1.086  -1.022  -0.958  -0.910  -0.997  -0.957  -0.895
157   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
158   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
159   K         0.267   0.271   0.135   0.172   0.188   0.011   0.195   0.198  -0.022
160   K        -0.503  -0.564  -0.569  -0.541  -0.660  -0.734  -0.521  -0.596  -0.596
161   E         1.123   1.042   0.994   1.044   0.914   0.815   1.148   0.998   0.875
162   L         1.206   1.252   1.086   1.486   1.545   1.363   1.289   1.361   1.052
163   S        -1.541  -1.557  -1.493  -1.546  -1.577  -1.492  -1.163  -1.168  -1.075
164   A        -1.134  -1.107  -1.072  -1.144  -1.079  -1.028  -0.988  -0.956  -0.887
165   E         1.206   1.109   1.060   1.202   1.069   1.003   1.289   1.117   1.003
166   K        -1.134  -1.151  -1.080  -1.156  -1.209  -1.105  -0.988  -0.993  -0.893
167   E        -0.014   0.046   0.022  -0.355  -0.299  -0.266  -0.287  -0.208  -0.218
168   A         0.086   0.019   0.054  -0.206  -0.286  -0.236  -0.112  -0.195  -0.162
169   Q        -1.948  -1.924  -1.832  -1.541  -1.504  -1.367  -1.338  -1.311  -1.196
170   A        -1.134  -1.135  -1.067  -1.325  -1.324  -1.212  -0.988  -0.980  -0.882
171   D         0.086  -0.014   0.026   0.296   0.181   0.250  -0.112  -0.251  -0.204
172   A         2.049   2.074   2.180   1.730   1.758   1.925   2.340   2.378   2.577
173   A        -0.981  -0.966  -0.998  -0.939  -0.908  -0.990  -0.812  -0.791  -0.805
174   A        -1.541  -1.569  -1.474  -1.709  -1.728  -1.598  -1.163  -1.178  -1.059
175   E         1.206   1.169   1.068   1.220   1.173   1.047   1.289   1.222   1.018
176   I        -0.981  -1.048  -1.040  -0.510  -0.622  -0.588  -0.812  -0.880  -0.849
177   A        -0.574  -0.619  -0.571  -0.927  -0.979  -0.924  -0.637  -0.674  -0.604
178   E         0.086   0.129   0.061  -0.019   0.034  -0.073  -0.112  -0.073  -0.155
179   D        -1.134  -1.077  -1.082  -1.068  -0.973  -1.014  -0.988  -0.925  -0.894
180   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
181   A        -0.574  -0.628  -0.588  -0.722  -0.780  -0.699  -0.637  -0.696  -0.628
182   E        -0.321  -0.421  -0.477  -0.256  -0.404  -0.517  -0.287  -0.415  -0.480
183   A        -0.981  -0.952  -1.017  -0.997  -0.949  -1.019  -0.812  -0.776  -0.825
184   E        -0.981  -0.941  -0.995  -0.838  -0.770  -0.859  -0.812  -0.768  -0.802
185   D        -1.134  -1.129  -1.075  -1.141  -1.139  -1.031  -0.988  -0.973  -0.889
186   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
187   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
188   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
189   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
190   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
191   A        -0.981  -0.825  -0.997  -0.748  -0.500  -0.805  -0.812  -0.633  -0.803
192   G        -1.541  -1.517  -1.464  -1.399  -1.392  -1.281  -1.163  -1.135  -1.051
193   K        -1.134  -1.067  -1.067  -1.320  -1.230  -1.207  -0.988  -0.920  -0.882
194   P        -0.321  -0.149  -0.423  -0.246  -0.005  -0.412  -0.287  -0.060  -0.410
195   K        -1.134  -1.092  -1.083  -1.387  -1.287  -1.284  -0.988  -0.939  -0.895
196   T        -1.541  -1.460  -1.464  -1.282  -1.187  -1.154  -1.163  -1.082  -1.051
197   A        -1.134  -1.075  -1.082  -1.054  -0.961  -1.001  -0.988  -0.923  -0.894
198   Q        -0.981  -1.048  -1.040  -0.726  -0.786  -0.717  -0.812  -0.880  -0.849
199   L        -0.981  -0.897  -0.985  -0.720  -0.615  -0.664  -0.812  -0.713  -0.791
200   S         0.820   0.755   0.813   0.732   0.624   0.705   0.589   0.449   0.507
201   L         1.206   1.205   1.074   1.499   1.504   1.369   1.289   1.283   1.029
202   Q        -1.134  -1.162  -1.072  -1.038  -1.082  -0.968  -0.988  -1.002  -0.886
203   D         0.646   0.692   0.776   0.375   0.446   0.567   0.238   0.320   0.429
204   Y         2.049   2.074   2.180   2.385   2.421   2.584   2.340   2.378   2.577
205   L         0.413   0.500   0.250   0.845   0.952   0.676   0.414   0.542   0.158
206   N         0.086   0.056   0.066  -0.210  -0.243  -0.230  -0.112  -0.135  -0.136
207   Q        -0.014   0.020   0.030  -0.011   0.023   0.063  -0.287  -0.242  -0.208
208   Q        -0.574  -0.599  -0.576  -0.256  -0.298  -0.240  -0.637  -0.662  -0.615
209   A        -1.134  -1.050  -1.065  -1.381  -1.263  -1.249  -0.988  -0.903  -0.880
210   -        -0.687  -0.674  -0.612  -1.002  -0.994  -0.884  -0.749  -0.731  -0.648
211   -        -0.118  -0.057  -0.028  -0.725  -0.638  -0.590  -0.406  -0.328  -0.282
212   -        -0.687  -0.704  -0.620  -0.871  -0.914  -0.762  -0.749  -0.766  -0.657
213   -        -0.118  -0.138  -0.042  -0.419  -0.485  -0.358  -0.406  -0.426  -0.298
214   -        -0.687  -0.723  -0.651  -1.032  -1.092  -1.025  -0.749  -0.787  -0.693
215   -         1.021   0.959   0.950   1.235   1.147   1.134   0.967   0.845   0.787
216   -        -0.087  -0.084  -0.021  -0.419  -0.442  -0.342  -0.342  -0.340  -0.261
217   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
219   -        -0.087  -0.127  -0.054  -0.404  -0.489  -0.418  -0.342  -0.402  -0.312
220   N        -1.134  -1.077  -1.082  -1.230  -1.123  -1.196  -0.988  -0.925  -0.894
221   N        -0.727  -0.709  -0.643  -0.854  -0.800  -0.693  -0.812  -0.782  -0.687
222   Q        -1.541  -1.541  -1.469  -1.383  -1.363  -1.246  -1.163  -1.154  -1.055
223   F        -0.014   0.052   0.022   0.161   0.246   0.255  -0.287  -0.202  -0.218
224   N         0.741   0.801   0.831   0.641   0.737   0.761   0.433   0.540   0.544
225   K        -0.028  -0.011   0.001  -0.231  -0.196  -0.163  -0.282  -0.262  -0.241
226   V         0.741   0.801   0.831   0.410   0.490   0.544   0.433   0.540   0.544
227   P         0.741   0.801   0.831   0.681   0.782   0.806   0.433   0.540   0.544
228   E         0.741   0.724   0.786   0.375   0.315   0.377   0.433   0.386   0.451
229   A         0.741   0.801   0.831   0.448   0.559   0.553   0.433   0.540   0.544
230   K        -0.503  -0.469  -0.558  -0.692  -0.634  -0.777  -0.521  -0.475  -0.582
231   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
232   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
233   -         0.894   0.879   0.875   0.738   0.711   0.699   0.731   0.693   0.637
234   K        -0.981  -1.008  -1.025  -0.972  -1.025  -1.016  -0.812  -0.839  -0.833
235   V         0.820   0.900   0.892   0.558   0.680   0.665   0.589   0.733   0.670
236   E        -0.574  -0.638  -0.583  -0.143  -0.199  -0.117  -0.637  -0.694  -0.618
237   L        -1.134  -1.072  -1.059  -1.147  -1.083  -1.030  -0.988  -0.925  -0.875
238   D        -1.541  -1.460  -1.464  -1.415  -1.262  -1.316  -1.163  -1.082  -1.051
239   A         0.413   0.554   0.257   0.285   0.465   0.081   0.414   0.621   0.168
240   E        -0.981  -1.053  -1.040  -0.840  -0.953  -0.930  -0.812  -0.885  -0.848
241   R        -0.321  -0.236  -0.443  -0.419  -0.286  -0.615  -0.287  -0.174  -0.437
242   I        -0.574  -0.612  -0.584  -0.178  -0.234  -0.202  -0.637  -0.680  -0.623
243   E        -0.321  -0.329  -0.460  -0.332  -0.339  -0.601  -0.287  -0.295  -0.458
244   T         1.206   1.289   1.089   1.072   1.180   0.942   1.289   1.421   1.058
245   A        -0.574  -0.487  -0.550  -0.548  -0.431  -0.521  -0.637  -0.544  -0.587
246   E        -0.574  -0.574  -0.552  -0.556  -0.584  -0.539  -0.637  -0.625  -0.580
247   K        -0.687  -0.677  -0.609  -0.570  -0.540  -0.467  -0.749  -0.734  -0.644
248   E         0.413   0.425   0.229   0.451   0.452   0.168   0.414   0.428   0.124
249   A        -0.727  -0.674  -0.633  -0.938  -0.863  -0.776  -0.812  -0.755  -0.680
250   Y        -0.167  -0.170  -0.077   0.149   0.132   0.270  -0.462  -0.467  -0.346
251   V        -0.574  -0.553  -0.550  -0.247  -0.202  -0.203  -0.637  -0.613  -0.586
252   P         0.820   0.900   0.892   0.482   0.593   0.586   0.589   0.733   0.670
253   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
254   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
255   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
256   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
257   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
258   A        -0.574  -0.511  -0.568  -0.789  -0.707  -0.751  -0.637  -0.571  -0.605
259   T         0.646   0.649   0.753   0.492   0.478   0.628   0.238   0.232   0.380
260   K        -0.981  -0.987  -1.018  -0.861  -0.869  -0.866  -0.812  -0.817  -0.826
261   V        -1.134  -1.145  -1.072  -1.187  -1.250  -1.101  -0.988  -0.988  -0.886
262   K         2.049   2.074   2.180   1.783   1.823   1.978   2.340   2.378   2.577
263   N        -0.574  -0.599  -0.576  -0.842  -0.860  -0.850  -0.637  -0.662  -0.615
264   V        -0.014  -0.012   0.019  -0.163  -0.163  -0.074  -0.287  -0.278  -0.223
265   K         0.086  -0.014   0.026  -0.233  -0.395  -0.350  -0.112  -0.251  -0.204
266   S        -0.981  -1.069  -1.046  -0.990  -1.151  -1.161  -0.812  -0.901  -0.855
267   K         0.086  -0.014   0.026  -0.181  -0.326  -0.268  -0.112  -0.251  -0.204
268   Q        -0.574  -0.618  -0.581  -0.709  -0.781  -0.714  -0.637  -0.672  -0.616
269   L        -1.134  -1.117  -1.087  -1.041  -1.057  -1.001  -0.988  -0.964  -0.899
270   K         1.206   1.109   1.060   1.066   0.950   0.890   1.289   1.117   1.003
271   T        -0.574  -0.618  -0.581  -0.561  -0.635  -0.568  -0.637  -0.672  -0.616
272   K         2.049   2.074   2.180   1.783   1.823   1.978   2.340   2.378   2.577
273   E        -0.574  -0.530  -0.543  -0.457  -0.360  -0.396  -0.637  -0.572  -0.570
274   Y        -0.574  -0.567  -0.582  -0.104  -0.115  -0.087  -0.637  -0.636  -0.622
275   L         2.049   2.074   2.180   2.176   2.209   2.373   2.340   2.378   2.577
276   E        -0.014   0.034   0.027  -0.093  -0.035   0.001  -0.287  -0.230  -0.213
277   F         0.820   0.900   0.892   1.136   1.262   1.239   0.589   0.733   0.670
278   D         0.646   0.647   0.752   0.404   0.386   0.539   0.238   0.226   0.378
279   A         0.086   0.010   0.025  -0.081  -0.169  -0.108  -0.112  -0.227  -0.206
280   T        -0.981  -0.952  -1.017  -0.745  -0.715  -0.851  -0.812  -0.776  -0.825
281   F         2.049   2.074   2.180   2.307   2.344   2.505   2.340   2.378   2.577
282   V        -1.541  -1.532  -1.463  -1.257  -1.227  -1.159  -1.163  -1.147  -1.050
283   E        -0.167  -0.174  -0.080  -0.487  -0.539  -0.403  -0.462  -0.472  -0.350
284   S        -1.157  -1.111  -1.077  -0.948  -0.859  -0.829  -0.997  -0.944  -0.886
285   N        -0.687  -0.698  -0.651  -0.648  -0.679  -0.603  -0.749  -0.760  -0.693
286   T        -0.687  -0.629  -0.614  -0.560  -0.473  -0.452  -0.749  -0.673  -0.650
287   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
288   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
289   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
290   R         1.021   1.072   0.991   1.036   1.107   0.986   0.967   1.051   0.870
291   K        -0.687  -0.651  -0.604  -0.745  -0.680  -0.641  -0.749  -0.701  -0.638
292   N        -0.118  -0.098  -0.028  -0.520  -0.490  -0.379  -0.406  -0.378  -0.282
293   F         0.097   0.117   0.082   0.167   0.195   0.144  -0.063  -0.032  -0.104
294   G         0.267   0.319   0.181   0.381   0.461   0.245   0.195   0.272   0.050
295   D        -0.682  -0.648  -0.606  -0.664  -0.604  -0.547  -0.759  -0.717  -0.648
296   R         2.049   2.074   2.180   2.014   2.044   2.210   2.340   2.378   2.577
297   N        -1.157  -1.125  -1.082  -1.007  -0.951  -0.898  -0.997  -0.960  -0.891
298   N        -0.682  -0.653  -0.605  -0.682  -0.622  -0.565  -0.759  -0.723  -0.647
299   N        -0.687  -0.698  -0.651  -0.586  -0.590  -0.529  -0.749  -0.760  -0.693
300   S        -0.798  -0.786  -0.678  -0.831  -0.813  -0.652  -0.878  -0.858  -0.724
301   R         2.049   2.074   2.180   2.067   2.095   2.264   2.340   2.378   2.577
302   N         0.267   0.235   0.132   0.296   0.233   0.051   0.195   0.141  -0.026
303   N        -0.503  -0.564  -0.569  -0.349  -0.431  -0.447  -0.521  -0.596  -0.596
304   F         1.021   0.931   0.918   1.238   1.080   1.008   0.967   0.793   0.722
305   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
306   N        -0.118  -0.068  -0.034  -0.245  -0.162  -0.120  -0.406  -0.341  -0.289
307   N        -0.687  -0.730  -0.651  -0.812  -0.892  -0.802  -0.749  -0.795  -0.693
308   R         0.267   0.234   0.129   0.401   0.350   0.178   0.195   0.140  -0.030
309   R         0.625   0.644   0.751   0.387   0.412   0.575   0.195   0.220   0.377
310   G         1.123   1.085   1.000   1.118   1.060   0.896   1.148   1.075   0.886
311   G        -0.028  -0.030   0.010  -0.248  -0.219  -0.168  -0.282  -0.271  -0.221
312   R         2.049   2.074   2.180   2.044   2.068   2.241   2.340   2.378   2.577
313   G         0.413   0.274   0.187   0.528   0.327   0.167   0.414   0.205   0.060
314   A         0.086   0.026   0.052  -0.047  -0.115  -0.128  -0.112  -0.185  -0.166
315   R        -1.134  -1.114  -1.066  -1.367  -1.335  -1.266  -0.988  -0.960  -0.881
316   K         1.206   1.289   1.089   1.269   1.371   1.093   1.289   1.421   1.058
317   G         2.049   2.074   2.180   2.032   2.072   2.229   2.340   2.378   2.577
318   N        -0.321  -0.367  -0.467  -0.160  -0.224  -0.404  -0.287  -0.348  -0.467
319   N        -1.134  -1.141  -1.080  -1.038  -1.046  -0.953  -0.988  -0.983  -0.892
320   T        -0.981  -1.021  -1.008  -0.816  -0.912  -0.884  -0.812  -0.853  -0.816
321   A        -0.321  -0.394  -0.473  -0.222  -0.319  -0.507  -0.287  -0.382  -0.475
322   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
323   N         0.267   0.338   0.163   0.299   0.409   0.111   0.195   0.301   0.022
324   A        -0.503  -0.516  -0.536  -0.620  -0.616  -0.652  -0.521  -0.536  -0.554
325   T        -1.157  -1.160  -1.088  -1.000  -0.989  -0.920  -0.997  -0.995  -0.897
326   N        -0.682  -0.701  -0.627  -0.562  -0.573  -0.455  -0.759  -0.771  -0.669
327   S        -0.574  -0.570  -0.578  -0.694  -0.717  -0.694  -0.637  -0.639  -0.618
328   A        -0.574  -0.488  -0.544  -0.725  -0.604  -0.696  -0.637  -0.546  -0.577
329   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
330   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
331   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
332   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
333   N        -0.981  -1.008  -1.025  -0.927  -0.979  -1.071  -0.812  -0.839  -0.833
334   T        -0.574  -0.511  -0.568  -0.577  -0.505  -0.588  -0.637  -0.571  -0.605
335   V        -0.981  -0.936  -0.990  -0.956  -0.883  -0.937  -0.812  -0.762  -0.797
336   Q        -0.574  -0.578  -0.575  -0.663  -0.653  -0.615  -0.637  -0.641  -0.614
337   K        -1.134  -1.131  -1.067  -1.371  -1.368  -1.241  -0.988  -0.975  -0.882
338   N        -1.134  -1.190  -1.106  -0.976  -1.005  -0.860  -0.988  -1.026  -0.916
339   R        -0.574  -0.508  -0.569  -0.498  -0.409  -0.512  -0.637  -0.567  -0.606
340   N        -1.948  -1.924  -1.832  -1.817  -1.724  -1.645  -1.338  -1.311  -1.196
341   I        -1.134  -1.190  -1.106  -0.678  -0.753  -0.645  -0.988  -1.026  -0.916
342   D        -0.167  -0.159  -0.061  -0.291  -0.284  -0.146  -0.462  -0.452  -0.323
343   V        -1.134  -1.092  -1.083  -1.065  -1.035  -0.988  -0.988  -0.939  -0.895
344   S         0.086   0.053   0.083  -0.066  -0.075  -0.052  -0.112  -0.139  -0.110
345   N        -0.574  -0.572  -0.581  -0.578  -0.580  -0.620  -0.637  -0.641  -0.621
346   L         0.820   0.900   0.892   1.044   1.172   1.141   0.589   0.733   0.670
347   P         2.049   2.074   2.180   2.132   2.157   2.329   2.340   2.378   2.577
348   S         0.820   0.755   0.813   0.565   0.418   0.468   0.589   0.449   0.507
349   L         2.049   2.074   2.180   2.176   2.209   2.373   2.340   2.378   2.577
350   A        -0.118  -0.074  -0.029  -0.357  -0.309  -0.206  -0.406  -0.350  -0.283
351   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P39015
Output conservation file - output/P39015
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
