1     M         1.002   1.019   1.067   1.284   1.304   1.349   1.050   1.072   1.143
2     A        -1.382  -1.430  -1.351  -1.367  -1.463  -1.361  -1.311  -1.350  -1.212
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     A         0.117   0.167  -0.068   0.066   0.139  -0.254   0.051   0.124  -0.285
6     V         0.196   0.030  -0.083   0.253   0.014  -0.173   0.169  -0.086  -0.310
7     T        -1.723  -1.851  -1.752  -1.444  -1.641  -1.544  -1.423  -1.536  -1.380
8     L         1.002   1.019   1.067   0.805   0.830   0.934   1.050   1.072   1.143
9     H         0.262   0.122  -0.054   0.580   0.405   0.130   0.263   0.057  -0.261
10    L         1.002   1.019   1.067   0.805   0.830   0.934   1.050   1.072   1.143
11    R         1.002   1.019   1.067   1.068   1.096   1.162   1.050   1.072   1.143
12    A        -0.444  -0.452  -0.774  -0.414  -0.428  -0.878  -0.411  -0.429  -0.846
13    E         1.002   1.019   1.067   0.953   0.980   1.063   1.050   1.072   1.143
14    T         1.002   1.019   1.067   1.036   1.062   1.134   1.050   1.072   1.143
15    K         1.002   1.019   1.067   0.963   1.001   1.071   1.050   1.072   1.143
16    P         0.262   0.155  -0.048   0.320   0.191  -0.083   0.263   0.106  -0.251
17    L         1.002   1.019   1.067   0.805   0.830   0.934   1.050   1.072   1.143
18    E         1.002   1.019   1.067   0.953   0.980   1.063   1.050   1.072   1.143
19    A        -0.913  -0.983  -0.842  -1.049  -1.132  -0.895  -1.086  -1.140  -0.938
20    R         1.002   1.019   1.067   1.068   1.096   1.162   1.050   1.072   1.143
21    A        -0.913  -0.862  -0.840  -1.126  -1.046  -0.949  -1.086  -1.028  -0.936
22    A         1.002   1.019   1.067   0.861   0.888   0.983   1.050   1.072   1.143
23    L         1.002   1.019   1.067   0.805   0.830   0.934   1.050   1.072   1.143
24    T         1.002   1.019   1.067   1.036   1.062   1.134   1.050   1.072   1.143
25    P         1.002   1.019   1.067   0.938   0.962   1.050   1.050   1.072   1.143
26    T        -0.767  -0.826  -0.818  -0.710  -0.776  -0.798  -0.861  -0.912  -0.905
27    T         1.002   1.019   1.067   1.036   1.062   1.134   1.050   1.072   1.143
28    V        -0.767  -0.773  -0.815  -0.774  -0.770  -0.900  -0.861  -0.839  -0.901
29    K        -0.444  -0.489  -0.776  -0.332  -0.394  -0.848  -0.411  -0.473  -0.849
30    K        -1.935  -1.967  -1.762  -1.749  -1.811  -1.509  -1.648  -1.650  -1.389
31    L         1.002   1.019   1.067   0.805   0.830   0.934   1.050   1.072   1.143
32    I        -0.913  -0.979  -0.843  -1.241  -1.327  -1.090  -1.086  -1.133  -0.939
33    A        -1.108  -1.021  -1.310  -0.928  -0.812  -1.304  -0.973  -0.878  -1.168
34    K        -0.298  -0.195  -0.136  -0.663  -0.477  -0.391  -0.636  -0.461  -0.405
35    G         1.002   1.019   1.067   1.002   1.033   1.105   1.050   1.072   1.143
36    F         0.262   0.155  -0.048   0.456   0.328   0.031   0.263   0.106  -0.251
37    K        -1.382  -1.523  -1.357  -1.357  -1.529  -1.298  -1.311  -1.431  -1.217
38    I        -0.298  -0.264  -0.153  -0.536  -0.486  -0.318  -0.636  -0.583  -0.435
39    Y        -1.382  -1.503  -1.358  -1.085  -1.256  -1.105  -1.311  -1.407  -1.218
40    V         0.262   0.122  -0.054   0.330   0.141  -0.138   0.263   0.057  -0.261
41    E         1.002   1.019   1.067   0.953   0.980   1.063   1.050   1.072   1.143
42    D        -1.594  -1.491  -1.370  -1.699  -1.544  -1.352  -1.535  -1.430  -1.230
43    S         1.002   1.019   1.067   1.043   1.074   1.141   1.050   1.072   1.143
44    P        -0.360  -0.324  -0.162  -0.657  -0.595  -0.330  -0.749  -0.691  -0.450
45    Q        -0.444  -0.489  -0.776  -0.125  -0.197  -0.733  -0.411  -0.473  -0.849
46    S        -0.298  -0.316  -0.162  -0.446  -0.487  -0.250  -0.636  -0.676  -0.451
47    T        -1.125  -1.100  -0.877  -1.387  -1.363  -1.023  -1.311  -1.267  -0.978
48    F         1.002   1.019   1.067   1.071   1.095   1.165   1.050   1.072   1.143
49    N        -0.767  -0.692  -0.825  -0.748  -0.668  -0.844  -0.861  -0.785  -0.917
50    I        -0.913  -0.817  -0.838  -1.069  -0.950  -0.951  -1.086  -0.989  -0.934
51    N        -2.063  -1.928  -1.764  -2.009  -1.843  -1.552  -1.760  -1.630  -1.391
52    E         1.002   1.019   1.067   0.953   0.980   1.063   1.050   1.072   1.143
53    Y        -0.298  -0.316  -0.162  -0.294  -0.357  -0.139  -0.636  -0.676  -0.451
54    R        -1.382  -1.194  -1.330  -1.372  -1.089  -1.307  -1.311  -1.081  -1.189
55    Q        -1.935  -1.831  -1.744  -1.839  -1.707  -1.565  -1.648  -1.544  -1.376
56    A        -0.913  -0.979  -0.843  -1.194  -1.301  -1.087  -1.086  -1.133  -0.939
57    G         1.002   1.019   1.067   1.002   1.033   1.105   1.050   1.072   1.143
58    A         0.262   0.122  -0.054   0.226   0.050  -0.200   0.263   0.057  -0.261
59    I        -1.382  -1.398  -1.339  -1.338  -1.347  -1.313  -1.311  -1.296  -1.198
60    I        -0.767  -0.900  -0.840  -0.794  -0.982  -0.899  -0.861  -1.017  -0.935
61    V         1.002   1.019   1.067   0.976   0.994   1.082   1.050   1.072   1.143
62    P         0.262   0.333  -0.036   0.286   0.376  -0.153   0.263   0.362  -0.230
63    A        -0.444  -0.237  -0.761  -0.341  -0.076  -0.829  -0.411  -0.148  -0.830
64    G         0.262   0.155  -0.048   0.384   0.261  -0.032   0.263   0.106  -0.251
65    S         1.002   1.019   1.067   1.043   1.074   1.141   1.050   1.072   1.143
66    W         1.002   1.019   1.067   1.255   1.274   1.324   1.050   1.072   1.143
67    K        -1.382  -1.415  -1.354  -1.377  -1.434  -1.334  -1.311  -1.342  -1.215
68    T        -1.935  -1.944  -1.759  -1.770  -1.766  -1.527  -1.648  -1.631  -1.387
69    A         1.002   1.019   1.067   0.861   0.888   0.983   1.050   1.072   1.143
70    P         1.002   1.019   1.067   0.938   0.962   1.050   1.050   1.072   1.143
71    R        -0.913  -0.790  -0.829  -1.045  -0.846  -0.897  -1.086  -0.916  -0.921
72    D        -0.103  -0.159  -0.137  -0.172  -0.272  -0.287  -0.299  -0.398  -0.407
73    R        -0.444  -0.675  -0.800  -0.206  -0.528  -0.763  -0.411  -0.708  -0.879
74    I        -0.444  -0.519  -0.782  -0.202  -0.298  -0.619  -0.411  -0.514  -0.857
75    I         1.002   1.019   1.067   0.997   1.025   1.100   1.050   1.072   1.143
76    I        -0.767  -0.800  -0.813  -0.754  -0.791  -0.839  -0.861  -0.880  -0.898
77    G         1.002   1.019   1.067   1.002   1.033   1.105   1.050   1.072   1.143
78    L         1.002   1.019   1.067   0.805   0.830   0.934   1.050   1.072   1.143
79    K         1.002   1.019   1.067   0.963   1.001   1.071   1.050   1.072   1.143
80    E         1.002   1.019   1.067   0.953   0.980   1.063   1.050   1.072   1.143
81    M        -0.298  -0.195  -0.136  -0.534  -0.392  -0.258  -0.636  -0.461  -0.405
82    P         0.262   0.155  -0.048   0.286   0.145  -0.176   0.263   0.106  -0.251
83    E         1.002   1.019   1.067   0.953   0.980   1.063   1.050   1.072   1.143
84    T        -2.044  -1.934  -1.767  -1.938  -1.778  -1.575  -1.740  -1.625  -1.393
85    D        -0.298  -0.229  -0.140  -0.533  -0.405  -0.292  -0.636  -0.521  -0.411
86    T        -1.265  -1.315  -1.350  -1.066  -1.150  -1.236  -1.152  -1.212  -1.208
87    F         0.262   0.122  -0.054   0.432   0.251  -0.044   0.263   0.057  -0.261
88    P         1.002   1.019   1.067   0.938   0.962   1.050   1.050   1.072   1.143
89    L         1.002   1.019   1.067   0.805   0.830   0.934   1.050   1.072   1.143
90    V        -1.382  -1.398  -1.354  -1.376  -1.442  -1.344  -1.311  -1.336  -1.215
91    H         1.002   1.019   1.067   1.190   1.210   1.268   1.050   1.072   1.143
92    E        -0.444  -0.675  -0.800  -0.328  -0.649  -0.864  -0.411  -0.708  -0.879
93    H         1.002   1.019   1.067   1.190   1.210   1.268   1.050   1.072   1.143
94    I         0.262   0.155  -0.048   0.348   0.211  -0.120   0.263   0.106  -0.251
95    Q         1.002   1.019   1.067   1.198   1.220   1.274   1.050   1.072   1.143
96    F         1.002   1.019   1.067   1.071   1.095   1.165   1.050   1.072   1.143
97    A         1.002   1.019   1.067   0.861   0.888   0.983   1.050   1.072   1.143
98    H         1.002   1.019   1.067   1.190   1.210   1.268   1.050   1.072   1.143
99    C         1.002   1.019   1.067   1.264   1.282   1.332   1.050   1.072   1.143
100   Y         1.002   1.019   1.067   1.216   1.240   1.290   1.050   1.072   1.143
101   K         1.002   1.019   1.067   0.963   1.001   1.071   1.050   1.072   1.143
102   D        -0.767  -0.891  -0.839  -0.671  -0.838  -0.752  -0.861  -1.011  -0.934
103   Q         1.002   1.019   1.067   1.198   1.220   1.274   1.050   1.072   1.143
104   A        -0.767  -0.790  -0.817  -0.914  -0.927  -0.982  -0.861  -0.861  -0.904
105   G         1.002   1.019   1.067   1.002   1.033   1.105   1.050   1.072   1.143
106   W         1.002   1.019   1.067   1.255   1.274   1.324   1.050   1.072   1.143
107   Q        -1.594  -1.626  -1.371  -1.614  -1.645  -1.276  -1.535  -1.537  -1.231
108   N        -0.767  -0.882  -0.835  -0.717  -0.883  -0.836  -0.861  -0.991  -0.929
109   V         1.002   1.019   1.067   0.976   0.994   1.082   1.050   1.072   1.143
110   L         1.002   1.019   1.067   0.805   0.830   0.934   1.050   1.072   1.143
111   M        -1.935  -1.860  -1.748  -1.763  -1.672  -1.512  -1.648  -1.552  -1.378
112   R         1.002   1.019   1.067   1.068   1.096   1.162   1.050   1.072   1.143
113   F         1.002   1.019   1.067   1.071   1.095   1.165   1.050   1.072   1.143
114   I        -0.767  -0.599  -0.805  -0.841  -0.583  -0.906  -0.861  -0.626  -0.888
115   K        -2.404  -2.232  -2.084  -2.252  -2.031  -1.794  -1.873  -1.724  -1.497
116   G         1.002   1.019   1.067   1.002   1.033   1.105   1.050   1.072   1.143
117   H        -1.108  -1.003  -1.302  -0.742  -0.629  -1.084  -0.973  -0.859  -1.159
118   G         1.002   1.019   1.067   1.002   1.033   1.105   1.050   1.072   1.143
119   T        -1.108  -1.186  -1.321  -0.915  -1.058  -1.325  -0.973  -1.060  -1.179
120   L         1.002   1.019   1.067   0.805   0.830   0.934   1.050   1.072   1.143
121   Y         0.262   0.155  -0.048   0.543   0.394  -0.006   0.263   0.106  -0.251
122   D         1.002   1.019   1.067   1.013   1.045   1.115   1.050   1.072   1.143
123   L         1.002   1.019   1.067   0.805   0.830   0.934   1.050   1.072   1.143
124   E         1.002   1.019   1.067   0.953   0.980   1.063   1.050   1.072   1.143
125   F         1.002   1.019   1.067   1.071   1.095   1.165   1.050   1.072   1.143
126   L         1.002   1.019   1.067   0.805   0.830   0.934   1.050   1.072   1.143
127   E        -0.444  -0.675  -0.800  -0.300  -0.608  -0.798  -0.411  -0.708  -0.879
128   N        -0.360  -0.314  -0.156  -0.534  -0.468  -0.219  -0.749  -0.673  -0.440
129   D         0.262   0.155  -0.048   0.361   0.228  -0.115   0.263   0.106  -0.251
130   Q        -0.913  -0.966  -0.840  -0.767  -0.835  -0.649  -1.086  -1.124  -0.936
131   G         1.002   1.019   1.067   1.002   1.033   1.105   1.050   1.072   1.143
132   R         1.002   1.019   1.067   1.068   1.096   1.162   1.050   1.072   1.143
133   R         1.002   1.019   1.067   1.068   1.096   1.162   1.050   1.072   1.143
134   V         1.002   1.019   1.067   0.976   0.994   1.082   1.050   1.072   1.143
135   A         1.002   1.019   1.067   0.861   0.888   0.983   1.050   1.072   1.143
136   A         1.002   1.019   1.067   0.861   0.888   0.983   1.050   1.072   1.143
137   F         1.002   1.019   1.067   1.071   1.095   1.165   1.050   1.072   1.143
138   G         1.002   1.019   1.067   1.002   1.033   1.105   1.050   1.072   1.143
139   F         0.262   0.122  -0.054   0.456   0.286   0.023   0.263   0.057  -0.261
140   Y        -0.298  -0.316  -0.162  -0.234  -0.285  -0.067  -0.636  -0.676  -0.451
141   A         1.002   1.019   1.067   0.861   0.888   0.983   1.050   1.072   1.143
142   G         1.002   1.019   1.067   1.002   1.033   1.105   1.050   1.072   1.143
143   F         1.002   1.019   1.067   1.071   1.095   1.165   1.050   1.072   1.143
144   A         1.002   1.019   1.067   0.861   0.888   0.983   1.050   1.072   1.143
145   G         1.002   1.019   1.067   1.002   1.033   1.105   1.050   1.072   1.143
146   A         0.262   0.122  -0.054   0.222   0.046  -0.211   0.263   0.057  -0.261
147   A         1.002   1.019   1.067   0.861   0.888   0.983   1.050   1.072   1.143
148   L        -0.913  -0.838  -0.836  -1.176  -1.065  -1.026  -1.086  -0.989  -0.931
149   G        -0.444  -0.675  -0.800  -0.296  -0.620  -0.870  -0.411  -0.708  -0.879
150   V        -1.382  -1.437  -1.350  -1.395  -1.480  -1.334  -1.311  -1.356  -1.211
151   R        -2.063  -1.913  -1.767  -2.127  -1.972  -1.675  -1.760  -1.621  -1.394
152   D        -0.767  -0.810  -0.840  -0.763  -0.882  -0.899  -0.861  -0.947  -0.935
153   W         1.002   1.019   1.067   1.255   1.274   1.324   1.050   1.072   1.143
154   A         0.262   0.262  -0.040   0.222   0.228  -0.189   0.263   0.262  -0.237
155   F        -0.444  -0.675  -0.800  -0.138  -0.434  -0.611  -0.411  -0.708  -0.879
156   K        -0.298  -0.316  -0.162  -0.447  -0.462  -0.219  -0.636  -0.676  -0.451
157   Q        -0.103  -0.221  -0.146  -0.039  -0.295  -0.250  -0.299  -0.507  -0.422
158   T        -0.767  -0.911  -0.840  -0.785  -1.036  -0.933  -0.861  -1.040  -0.934
159   H         0.262   0.262  -0.040   0.563   0.560   0.109   0.263   0.262  -0.237
160   S        -1.508  -1.464  -1.363  -1.548  -1.519  -1.361  -1.446  -1.396  -1.223
161   D        -0.174  -0.259  -0.153  -0.230  -0.378  -0.222  -0.418  -0.573  -0.435
162   D        -1.723  -1.656  -1.731  -1.431  -1.365  -1.498  -1.423  -1.355  -1.363
163   E        -0.444  -0.582  -0.786  -0.302  -0.476  -0.784  -0.411  -0.590  -0.863
164   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
165   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
166   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
167   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
168   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
169   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
170   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
171   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
172   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
173   D        -1.508  -1.582  -1.369  -1.484  -1.608  -1.305  -1.446  -1.496  -1.228
174   L        -0.103  -0.221  -0.146  -0.335  -0.532  -0.387  -0.299  -0.507  -0.422
175   P        -0.444  -0.271  -0.759  -0.333  -0.118  -0.788  -0.411  -0.191  -0.827
176   A        -0.360  -0.325  -0.162  -0.744  -0.684  -0.407  -0.749  -0.693  -0.450
177   V        -0.103  -0.147  -0.142  -0.194  -0.282  -0.300  -0.299  -0.378  -0.415
178   S        -1.594  -1.625  -1.370  -1.636  -1.674  -1.308  -1.535  -1.535  -1.229
179   P        -0.444  -0.489  -0.776  -0.361  -0.424  -0.877  -0.411  -0.473  -0.849
180   Y         0.262   0.122  -0.054   0.579   0.398   0.080   0.263   0.057  -0.261
181   P         0.262   0.328  -0.039   0.286   0.370  -0.159   0.263   0.355  -0.235
182   N         1.002   1.019   1.067   1.138   1.155   1.222   1.050   1.072   1.143
183   E         1.002   1.019   1.067   0.953   0.980   1.063   1.050   1.072   1.143
184   K        -1.935  -1.855  -1.748  -1.855  -1.737  -1.580  -1.648  -1.559  -1.379
185   A        -0.913  -0.966  -0.839  -1.182  -1.229  -1.006  -1.086  -1.114  -0.934
186   L         0.262   0.328  -0.039   0.202   0.282  -0.137   0.263   0.355  -0.235
187   V        -0.298  -0.277  -0.158  -0.536  -0.510  -0.329  -0.636  -0.605  -0.444
188   K        -1.382  -1.428  -1.351  -1.425  -1.490  -1.383  -1.311  -1.347  -1.212
189   D        -0.444  -0.519  -0.782  -0.244  -0.333  -0.736  -0.411  -0.514  -0.857
190   V        -0.103   0.005  -0.115  -0.194  -0.032  -0.250  -0.299  -0.127  -0.368
191   T        -1.723  -1.625  -1.737  -1.553  -1.438  -1.627  -1.423  -1.323  -1.368
192   K        -0.767  -0.809  -0.830  -0.783  -0.845  -0.883  -0.861  -0.919  -0.923
193   D        -1.935  -1.926  -1.755  -1.896  -1.885  -1.639  -1.648  -1.623  -1.384
194   Y        -1.125  -1.111  -0.880  -1.338  -1.343  -0.974  -1.311  -1.281  -0.982
195   K        -2.275  -2.207  -2.079  -2.073  -1.977  -1.830  -1.760  -1.687  -1.494
196   E        -1.935  -1.843  -1.747  -2.029  -1.934  -1.756  -1.648  -1.556  -1.378
197   A         0.262   0.155  -0.048   0.216   0.082  -0.218   0.263   0.106  -0.251
198   L        -0.103  -0.125  -0.130  -0.368  -0.414  -0.416  -0.299  -0.342  -0.395
199   A        -1.382  -1.316  -1.334  -1.426  -1.338  -1.378  -1.311  -1.242  -1.195
200   T        -1.382  -1.328  -1.341  -1.380  -1.287  -1.335  -1.311  -1.224  -1.200
201   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
202   G        -0.444  -0.675  -0.800  -0.280  -0.599  -0.832  -0.411  -0.708  -0.879
203   A        -1.465  -1.469  -1.357  -1.563  -1.532  -1.331  -1.423  -1.400  -1.218
204   R        -1.594  -1.483  -1.366  -1.559  -1.388  -1.240  -1.535  -1.421  -1.226
205   K        -1.125  -1.088  -0.877  -1.309  -1.240  -0.957  -1.311  -1.252  -0.978
206   P         1.002   1.019   1.067   0.938   0.962   1.050   1.050   1.072   1.143
207   T        -1.594  -1.488  -1.370  -1.606  -1.466  -1.247  -1.535  -1.428  -1.230
208   V        -0.767  -0.826  -0.818  -0.695  -0.781  -0.766  -0.861  -0.912  -0.905
209   L         0.262   0.155  -0.048   0.158   0.023  -0.266   0.263   0.106  -0.251
210   I        -0.298  -0.195  -0.136  -0.543  -0.367  -0.289  -0.636  -0.461  -0.405
211   I         1.002   1.019   1.067   0.997   1.025   1.100   1.050   1.072   1.143
212   G         1.002   1.019   1.067   1.002   1.033   1.105   1.050   1.072   1.143
213   A         1.002   1.019   1.067   0.861   0.888   0.983   1.050   1.072   1.143
214   L         0.262   0.155  -0.048   0.169   0.037  -0.238   0.263   0.106  -0.251
215   G         1.002   1.019   1.067   1.002   1.033   1.105   1.050   1.072   1.143
216   R         1.002   1.019   1.067   1.068   1.096   1.162   1.050   1.072   1.143
217   C         1.002   1.019   1.067   1.264   1.282   1.332   1.050   1.072   1.143
218   G         1.002   1.019   1.067   1.002   1.033   1.105   1.050   1.072   1.143
219   S         0.262   0.122  -0.054   0.403   0.227  -0.069   0.263   0.057  -0.261
220   G         1.002   1.019   1.067   1.002   1.033   1.105   1.050   1.072   1.143
221   A         1.002   1.019   1.067   0.861   0.888   0.983   1.050   1.072   1.143
222   I        -1.723  -1.767  -1.743  -1.532  -1.595  -1.635  -1.423  -1.463  -1.373
223   D         0.262   0.155  -0.048   0.374   0.246  -0.080   0.263   0.106  -0.251
224   L        -0.767  -0.741  -0.813  -0.958  -0.912  -1.016  -0.861  -0.797  -0.898
225   L        -1.041  -1.015  -0.860  -1.393  -1.371  -1.104  -1.198  -1.159  -0.957
226   H        -1.382  -1.348  -1.343  -1.296  -1.244  -1.211  -1.311  -1.259  -1.204
227   K         1.002   1.019   1.067   0.963   1.001   1.071   1.050   1.072   1.143
228   V        -1.382  -1.448  -1.353  -1.339  -1.483  -1.289  -1.311  -1.377  -1.214
229   G         1.002   1.019   1.067   1.002   1.033   1.105   1.050   1.072   1.143
230   I        -0.103   0.002  -0.107  -0.235  -0.060  -0.307  -0.299  -0.132  -0.354
231   P         1.002   1.019   1.067   0.938   0.962   1.050   1.050   1.072   1.143
232   D        -0.913  -0.957  -0.838  -1.050  -1.073  -0.897  -1.086  -1.100  -0.933
233   A        -0.767  -0.733  -0.826  -0.839  -0.825  -0.961  -0.861  -0.850  -0.918
234   N         0.262   0.396  -0.034   0.486   0.645   0.016   0.263   0.446  -0.226
235   I         0.262   0.396  -0.034   0.324   0.497  -0.155   0.263   0.446  -0.226
236   L        -0.913  -0.905  -0.835  -1.200  -1.218  -1.079  -1.086  -1.067  -0.930
237   K        -0.767  -0.889  -0.840  -0.780  -0.949  -0.892  -0.861  -1.008  -0.935
238   W         1.002   1.019   1.067   1.255   1.274   1.324   1.050   1.072   1.143
239   D         1.002   1.019   1.067   1.013   1.045   1.115   1.050   1.072   1.143
240   I        -0.298  -0.267  -0.156  -0.272  -0.230  -0.118  -0.636  -0.588  -0.441
241   K        -1.594  -1.536  -1.372  -1.657  -1.601  -1.300  -1.535  -1.473  -1.232
242   E         1.002   1.019   1.067   0.953   0.980   1.063   1.050   1.072   1.143
243   T         1.002   1.019   1.067   1.036   1.062   1.134   1.050   1.072   1.143
244   S        -1.041  -0.973  -0.858  -1.311  -1.208  -1.024  -1.198  -1.107  -0.954
245   R        -0.298  -0.195  -0.136  -0.517  -0.330  -0.262  -0.636  -0.461  -0.405
246   G         1.002   1.019   1.067   1.002   1.033   1.105   1.050   1.072   1.143
247   G         1.002   1.019   1.067   1.002   1.033   1.105   1.050   1.072   1.143
248   P         1.002   1.019   1.067   0.938   0.962   1.050   1.050   1.072   1.143
249   F         1.002   1.019   1.067   1.071   1.095   1.165   1.050   1.072   1.143
250   D        -1.723  -1.743  -1.747  -1.332  -1.398  -1.503  -1.423  -1.442  -1.376
251   E         1.002   1.019   1.067   0.953   0.980   1.063   1.050   1.072   1.143
252   I         1.002   1.019   1.067   0.997   1.025   1.100   1.050   1.072   1.143
253   P        -1.594  -1.507  -1.369  -1.801  -1.675  -1.441  -1.535  -1.445  -1.229
254   Q        -1.382  -1.307  -1.334  -1.285  -1.177  -1.255  -1.311  -1.206  -1.194
255   A        -0.298  -0.210  -0.143  -0.554  -0.381  -0.326  -0.636  -0.486  -0.418
256   D         1.002   1.019   1.067   1.013   1.045   1.115   1.050   1.072   1.143
257   I         0.262   0.328  -0.039   0.348   0.434  -0.103   0.263   0.355  -0.235
258   F         1.002   1.019   1.067   1.071   1.095   1.165   1.050   1.072   1.143
259   I        -0.298  -0.310  -0.161  -0.536  -0.578  -0.336  -0.636  -0.664  -0.450
260   N         1.002   1.019   1.067   1.138   1.155   1.222   1.050   1.072   1.143
261   C         1.002   1.019   1.067   1.264   1.282   1.332   1.050   1.072   1.143
262   I         1.002   1.019   1.067   0.997   1.025   1.100   1.050   1.072   1.143
263   Y         1.002   1.019   1.067   1.216   1.240   1.290   1.050   1.072   1.143
264   L         1.002   1.019   1.067   0.805   0.830   0.934   1.050   1.072   1.143
265   S         0.262   0.155  -0.048   0.403   0.272  -0.059   0.263   0.106  -0.251
266   K        -1.382  -1.480  -1.353  -1.215  -1.311  -1.126  -1.311  -1.382  -1.213
267   P         0.262   0.155  -0.048   0.287   0.149  -0.172   0.263   0.106  -0.251
268   I         1.002   1.019   1.067   0.997   1.025   1.100   1.050   1.072   1.143
269   A        -0.103   0.038  -0.094  -0.275  -0.049  -0.301  -0.299  -0.075  -0.331
270   P        -0.444  -0.675  -0.800  -0.328  -0.643  -0.839  -0.411  -0.708  -0.879
271   F         1.002   1.019   1.067   1.071   1.095   1.165   1.050   1.072   1.143
272   T        -1.108  -1.223  -1.328  -0.855  -1.019  -1.174  -0.973  -1.107  -1.186
273   N        -0.444  -0.462  -0.775  -0.138  -0.186  -0.673  -0.411  -0.448  -0.848
274   M        -1.935  -1.961  -1.756  -1.524  -1.587  -1.342  -1.648  -1.647  -1.385
275   E         0.262   0.333  -0.036   0.309   0.402  -0.118   0.263   0.362  -0.230
276   K        -1.935  -1.812  -1.755  -2.019  -1.836  -1.723  -1.648  -1.537  -1.384
277   L         1.002   1.019   1.067   0.805   0.830   0.934   1.050   1.072   1.143
278   N         0.262   0.155  -0.048   0.519   0.383   0.076   0.263   0.106  -0.251
279   N        -1.125  -1.052  -0.870  -1.325  -1.215  -0.926  -1.311  -1.209  -0.969
280   P        -0.103  -0.062  -0.117  -0.245  -0.185  -0.303  -0.299  -0.236  -0.371
281   N        -1.125  -1.059  -0.872  -1.228  -1.125  -0.856  -1.311  -1.220  -0.972
282   R         1.002   1.019   1.067   1.068   1.096   1.162   1.050   1.072   1.143
283   R        -0.767  -0.771  -0.816  -0.745  -0.708  -0.786  -0.861  -0.838  -0.902
284   L         1.002   1.019   1.067   0.805   0.830   0.934   1.050   1.072   1.143
285   R        -0.444  -0.391  -0.764  -0.203  -0.131  -0.694  -0.411  -0.342  -0.833
286   T        -0.298  -0.316  -0.162  -0.501  -0.563  -0.312  -0.636  -0.676  -0.451
287   V        -0.298  -0.229  -0.140  -0.543  -0.430  -0.296  -0.636  -0.521  -0.411
288   V        -0.103  -0.221  -0.146  -0.106  -0.293  -0.161  -0.299  -0.507  -0.422
289   D         1.002   1.019   1.067   1.013   1.045   1.115   1.050   1.072   1.143
290   V         1.002   1.019   1.067   0.976   0.994   1.082   1.050   1.072   1.143
291   S         1.002   1.019   1.067   1.043   1.074   1.141   1.050   1.072   1.143
292   A         0.262   0.122  -0.054   0.255   0.092  -0.121   0.263   0.057  -0.261
293   D         1.002   1.019   1.067   1.013   1.042   1.114   1.050   1.072   1.143
294   T         1.002   1.019   1.067   1.026   1.051   1.125   1.050   1.072   1.143
295   T         1.002   1.019   1.067   1.026   1.051   1.125   1.050   1.072   1.143
296   N         0.196   0.096  -0.064   0.418   0.277  -0.007   0.169   0.017  -0.278
297   P         1.002   1.019   1.067   0.931   0.954   1.044   1.050   1.072   1.143
298   H        -0.563  -0.780  -0.819  -0.223  -0.542  -0.653  -0.565  -0.846  -0.904
299   N         0.196   0.096  -0.064   0.416   0.272  -0.014   0.169   0.017  -0.278
300   P         1.002   1.019   1.067   0.931   0.954   1.044   1.050   1.072   1.143
301   I        -0.340  -0.314  -0.160  -0.621  -0.586  -0.334  -0.712  -0.671  -0.447
302   P         1.002   1.019   1.067   0.931   0.954   1.044   1.050   1.072   1.143
303   I        -0.174  -0.084  -0.122  -0.299  -0.150  -0.256  -0.418  -0.272  -0.379
304   Y         1.002   1.019   1.067   1.216   1.240   1.290   1.050   1.072   1.143
305   T        -0.876  -0.820  -0.836  -0.849  -0.787  -0.795  -1.006  -0.944  -0.930
306   V        -0.340  -0.326  -0.161  -0.621  -0.615  -0.338  -0.712  -0.693  -0.449
307   A        -0.174  -0.208  -0.149  -0.371  -0.429  -0.315  -0.418  -0.483  -0.428
308   T         1.002   1.019   1.067   1.026   1.051   1.125   1.050   1.072   1.143
309   V        -0.340  -0.247  -0.145  -0.603  -0.433  -0.286  -0.712  -0.552  -0.420
310   F         1.002   1.019   1.067   1.071   1.095   1.165   1.050   1.072   1.143
311   N        -0.360  -0.309  -0.154  -0.534  -0.459  -0.217  -0.749  -0.663  -0.437
312   K        -1.935  -1.833  -1.751  -1.838  -1.691  -1.601  -1.648  -1.548  -1.381
313   P         1.002   1.019   1.067   0.938   0.962   1.050   1.050   1.072   1.143
314   T         1.002   1.019   1.067   1.036   1.062   1.134   1.050   1.072   1.143
315   V         1.002   1.019   1.067   0.976   0.994   1.082   1.050   1.072   1.143
316   L        -1.935  -1.783  -1.750  -1.954  -1.763  -1.686  -1.648  -1.511  -1.380
317   V         1.002   1.019   1.067   0.976   0.994   1.082   1.050   1.072   1.143
318   P        -2.063  -1.993  -1.769  -2.112  -2.002  -1.657  -1.760  -1.674  -1.395
319   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
320   T        -0.767  -0.923  -0.840  -0.816  -1.091  -0.998  -0.861  -1.050  -0.934
321   T        -0.767  -0.651  -0.807  -0.720  -0.529  -0.799  -0.861  -0.686  -0.891
322   A        -1.935  -1.961  -1.755  -1.967  -1.992  -1.686  -1.648  -1.648  -1.384
323   G         0.262   0.122  -0.054   0.348   0.166  -0.140   0.263   0.057  -0.261
324   P         0.262   0.262  -0.040   0.265   0.265  -0.217   0.263   0.262  -0.237
325   K        -0.103  -0.221  -0.146  -0.226  -0.438  -0.349  -0.299  -0.507  -0.422
326   L         1.002   1.019   1.067   0.805   0.830   0.934   1.050   1.072   1.143
327   S         0.262   0.122  -0.054   0.391   0.210  -0.101   0.263   0.057  -0.261
328   V         1.002   1.019   1.067   0.976   0.994   1.082   1.050   1.072   1.143
329   I        -0.360  -0.319  -0.158  -0.454  -0.406  -0.158  -0.749  -0.681  -0.443
330   S         1.002   1.019   1.067   1.043   1.074   1.141   1.050   1.072   1.143
331   I         1.002   1.019   1.067   0.997   1.025   1.100   1.050   1.072   1.143
332   D         1.002   1.019   1.067   1.013   1.045   1.115   1.050   1.072   1.143
333   H         1.002   1.019   1.067   1.190   1.210   1.268   1.050   1.072   1.143
334   L         1.002   1.019   1.067   0.805   0.830   0.934   1.050   1.072   1.143
335   P         1.002   1.019   1.067   0.938   0.962   1.050   1.050   1.072   1.143
336   S         0.262   0.122  -0.054   0.403   0.227  -0.069   0.263   0.057  -0.261
337   L         1.002   1.019   1.067   0.805   0.830   0.934   1.050   1.072   1.143
338   L         1.002   1.019   1.067   0.805   0.830   0.934   1.050   1.072   1.143
339   P         1.002   1.019   1.067   0.938   0.962   1.050   1.050   1.072   1.143
340   R         0.262   0.328  -0.039   0.417   0.506  -0.051   0.263   0.355  -0.235
341   E         1.002   1.019   1.067   0.953   0.980   1.063   1.050   1.072   1.143
342   A         0.262   0.122  -0.054   0.222   0.046  -0.211   0.263   0.057  -0.261
343   S         1.002   1.019   1.067   1.043   1.074   1.141   1.050   1.072   1.143
344   E         1.002   1.019   1.067   0.953   0.980   1.063   1.050   1.072   1.143
345   F        -0.913  -0.862  -0.840  -1.063  -1.033  -0.938  -1.086  -1.028  -0.936
346   F         1.002   1.019   1.067   1.071   1.095   1.165   1.050   1.072   1.143
347   S        -0.298  -0.216  -0.138  -0.554  -0.395  -0.313  -0.636  -0.498  -0.408
348   H        -1.594  -1.528  -1.366  -1.560  -1.479  -1.247  -1.535  -1.456  -1.226
349   D        -0.103  -0.145  -0.136  -0.201  -0.281  -0.330  -0.299  -0.374  -0.404
350   L         1.002   1.019   1.067   0.805   0.830   0.934   1.050   1.072   1.143
351   L        -0.767  -0.826  -0.818  -0.845  -0.923  -0.872  -0.861  -0.912  -0.905
352   P         1.002   1.019   1.067   0.938   0.962   1.050   1.050   1.072   1.143
353   S         1.002   1.019   1.067   1.043   1.074   1.141   1.050   1.072   1.143
354   L         1.002   1.019   1.067   0.805   0.830   0.934   1.050   1.072   1.143
355   E        -0.298  -0.195  -0.136  -0.719  -0.541  -0.438  -0.636  -0.461  -0.405
356   L        -1.935  -1.961  -1.762  -1.807  -1.875  -1.649  -1.648  -1.646  -1.388
357   L         1.002   1.019   1.067   0.805   0.830   0.934   1.050   1.072   1.143
358   P        -0.444  -0.675  -0.800  -0.328  -0.643  -0.839  -0.411  -0.708  -0.879
359   Q        -1.594  -1.513  -1.370  -1.446  -1.375  -1.160  -1.535  -1.450  -1.229
360   R        -0.444  -0.675  -0.800  -0.177  -0.487  -0.694  -0.411  -0.708  -0.879
361   K        -1.723  -1.602  -1.734  -1.443  -1.275  -1.497  -1.423  -1.298  -1.365
362   T        -0.767  -0.778  -0.836  -0.691  -0.754  -0.814  -0.861  -0.915  -0.929
363   A        -0.360  -0.326  -0.162  -0.713  -0.656  -0.381  -0.749  -0.693  -0.450
364   P         0.262   0.328  -0.039   0.299   0.382  -0.125   0.263   0.355  -0.235
365   V         1.002   1.019   1.067   0.976   0.994   1.082   1.050   1.072   1.143
366   W         1.002   1.019   1.067   1.255   1.274   1.324   1.050   1.072   1.143
367   V        -0.444  -0.489  -0.776  -0.324  -0.406  -0.851  -0.411  -0.473  -0.849
368   R         0.262   0.328  -0.039   0.417   0.506  -0.051   0.263   0.355  -0.235
369   A         1.002   1.019   1.067   0.861   0.888   0.983   1.050   1.072   1.143
370   K        -0.444  -0.291  -0.762  -0.317  -0.108  -0.791  -0.411  -0.216  -0.831
371   K        -1.465  -1.367  -1.346  -1.392  -1.254  -1.223  -1.423  -1.315  -1.208
372   L         1.002   1.019   1.067   0.805   0.830   0.934   1.050   1.072   1.143
373   F        -0.103  -0.147  -0.142  -0.031  -0.104  -0.117  -0.299  -0.378  -0.415
374   D        -0.767  -0.719  -0.826  -0.752  -0.720  -0.851  -0.861  -0.822  -0.918
375   R        -1.382  -1.469  -1.353  -1.352  -1.455  -1.316  -1.311  -1.368  -1.212
376   H        -1.108  -1.267  -1.334  -0.660  -0.891  -1.044  -0.973  -1.151  -1.193
377   C        -1.108  -0.874  -1.301  -0.896  -0.606  -1.188  -0.973  -0.700  -1.159
378   A        -0.444  -0.519  -0.782  -0.420  -0.512  -0.905  -0.411  -0.514  -0.857
379   R        -0.767  -0.891  -0.839  -0.716  -0.907  -0.870  -0.861  -1.011  -0.934
380   V        -1.382  -1.180  -1.331  -1.573  -1.276  -1.484  -1.311  -1.073  -1.191
381   K        -2.044  -1.981  -1.774  -2.067  -1.992  -1.692  -1.740  -1.666  -1.398
382   R        -0.986  -1.009  -0.862  -1.106  -1.164  -0.947  -1.148  -1.168  -0.960
383   S        -1.071  -1.002  -0.862  -1.249  -1.152  -0.923  -1.252  -1.160  -0.961
384   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
385   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
386   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
387   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P38998
Output conservation file - output/P38998
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
