1     M         2.699   2.729   2.887   2.948   2.995   3.264   3.207   3.264   3.581
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    S         0.510   0.524   0.577   0.346   0.362   0.438   0.155   0.180   0.238
14    N         0.010  -0.027  -0.044  -0.055  -0.113  -0.159  -0.123  -0.175  -0.208
15    -        -0.785  -0.764  -0.699  -0.833  -0.770  -0.713  -0.789  -0.766  -0.686
16    -        -0.185  -0.168  -0.121  -0.308  -0.297  -0.232  -0.389  -0.370  -0.314
17    -        -0.785  -0.764  -0.699  -0.771  -0.733  -0.647  -0.789  -0.766  -0.686
18    -        -0.785  -0.764  -0.699  -0.829  -0.801  -0.708  -0.789  -0.766  -0.686
19    -        -0.185  -0.164  -0.115  -0.329  -0.312  -0.245  -0.389  -0.365  -0.306
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    E        -1.084  -1.024  -1.031  -0.966  -0.881  -0.891  -0.870  -0.810  -0.796
24    L        -0.494  -0.550  -0.556  -0.457  -0.542  -0.591  -0.463  -0.529  -0.528
25    R        -0.656  -0.597  -0.599  -0.680  -0.606  -0.599  -0.667  -0.607  -0.587
26    L         2.699   2.729   2.887   2.443   2.489   2.733   3.207   3.264   3.581
27    E        -0.535  -0.577  -0.563  -0.470  -0.539  -0.520  -0.539  -0.576  -0.547
28    D         0.357   0.350   0.451   0.031   0.009   0.148  -0.071  -0.084   0.044
29    N        -0.019  -0.038  -0.019  -0.072  -0.096  -0.057  -0.227  -0.242  -0.205
30    Y        -0.302  -0.411  -0.473   0.013  -0.172  -0.287  -0.227  -0.361  -0.428
31    V         0.750   0.765   0.693   0.758   0.747   0.651   0.553   0.539   0.432
32    P         0.202   0.086   0.044   0.309   0.115   0.006   0.149  -0.017  -0.083
33    T        -0.494  -0.400  -0.490  -0.423  -0.293  -0.416  -0.463  -0.349  -0.449
34    S         0.010  -0.048  -0.052  -0.194  -0.274  -0.298  -0.123  -0.206  -0.218
35    D        -1.427  -1.419  -1.398  -1.192  -1.182  -1.149  -1.007  -0.998  -0.952
36    T        -1.052  -1.015  -1.010  -0.945  -0.901  -0.884  -0.851  -0.816  -0.784
37    L        -0.910  -0.910  -0.969  -0.884  -0.875  -1.005  -0.695  -0.693  -0.735
38    V        -0.302  -0.391  -0.458  -0.162  -0.313  -0.457  -0.227  -0.337  -0.409
39    V        -0.677  -0.670  -0.622  -0.917  -0.886  -0.815  -0.695  -0.682  -0.614
40    F        -1.052  -1.054  -1.016  -0.757  -0.758  -0.699  -0.851  -0.849  -0.789
41    K         0.590   0.606   0.615   0.350   0.367   0.383   0.241   0.253   0.273
42    Q        -0.535  -0.554  -0.557  -0.648  -0.690  -0.695  -0.539  -0.557  -0.543
43    L         2.699   2.729   2.887   2.437   2.482   2.726   3.207   3.264   3.581
44    M        -0.302  -0.166  -0.365  -0.065   0.136  -0.150  -0.227  -0.054  -0.294
45    K         1.482   1.524   1.502   1.414   1.475   1.397   1.334   1.411   1.285
46    L         1.107   1.027   0.908   1.071   0.974   0.846   1.178   1.047   0.835
47    P        -0.535  -0.489  -0.520  -0.546  -0.482  -0.522  -0.539  -0.492  -0.503
48    V        -0.535  -0.493  -0.531  -0.401  -0.341  -0.377  -0.539  -0.486  -0.510
49    T        -1.052  -1.016  -1.007  -0.932  -0.880  -0.860  -0.851  -0.817  -0.781
50    V        -0.910  -0.931  -0.968  -0.677  -0.708  -0.742  -0.695  -0.715  -0.734
51    L         1.482   1.527   1.511   1.096   1.169   1.094   1.334   1.416   1.307
52    Y        -0.160  -0.150  -0.119  -0.335  -0.326  -0.236  -0.383  -0.375  -0.328
53    D        -1.052  -1.022  -1.014  -1.007  -0.973  -0.947  -0.851  -0.820  -0.787
54    L         1.884   1.963   1.832   1.731   1.834   1.698   2.114   2.255   1.997
55    T        -1.052  -1.057  -1.016  -0.831  -0.827  -0.756  -0.851  -0.852  -0.789
56    L        -1.052  -1.002  -1.007  -1.066  -1.001  -0.993  -0.851  -0.805  -0.781
57    S        -1.427  -1.421  -1.387  -1.617  -1.601  -1.573  -1.007  -0.999  -0.942
58    W         2.699   2.729   2.887   3.012   3.061   3.332   3.207   3.264   3.581
59    F        -0.535  -0.485  -0.518  -0.684  -0.635  -0.651  -0.539  -0.480  -0.499
60    A        -1.052  -1.049  -1.029  -0.941  -0.927  -0.882  -0.851  -0.843  -0.799
61    K        -0.535  -0.540  -0.546  -0.782  -0.761  -0.797  -0.539  -0.531  -0.525
62    F        -1.052  -1.067  -1.025  -0.908  -0.913  -0.873  -0.851  -0.860  -0.797
63    G        -0.535  -0.577  -0.563  -0.456  -0.502  -0.485  -0.539  -0.576  -0.547
64    G        -1.427  -1.451  -1.420  -1.139  -1.184  -1.126  -1.007  -1.023  -0.969
65    S        -1.427  -1.451  -1.420  -1.232  -1.277  -1.255  -1.007  -1.023  -0.969
66    F        -0.302  -0.291  -0.428  -0.084  -0.083  -0.307  -0.227  -0.213  -0.372
67    D        -0.785  -0.769  -0.699  -0.805  -0.803  -0.684  -0.789  -0.770  -0.686
68    G        -0.785  -0.769  -0.699  -0.845  -0.822  -0.726  -0.789  -0.770  -0.686
69    D         0.416   0.418   0.508   0.225   0.219   0.360   0.010   0.013   0.128
70    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
71    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
72    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
73    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
74    I        -0.227  -0.222  -0.151  -0.509  -0.470  -0.392  -0.463  -0.450  -0.362
75    Y        -0.494  -0.425  -0.498  -0.373  -0.280  -0.374  -0.463  -0.382  -0.459
76    -        -0.679  -0.690  -0.627  -0.645  -0.680  -0.586  -0.678  -0.689  -0.610
77    -        -0.179  -0.130  -0.104  -0.384  -0.310  -0.283  -0.400  -0.344  -0.305
78    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
79    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
80    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
81    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
82    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
83    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
84    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
85    L        -0.656  -0.670  -0.621  -0.871  -0.878  -0.834  -0.667  -0.676  -0.609
86    L         0.525   0.556   0.586   0.239   0.261   0.315   0.149   0.191   0.236
87    T        -0.677  -0.709  -0.623  -0.830  -0.879  -0.756  -0.695  -0.717  -0.617
88    E         0.590   0.626   0.613   0.531   0.554   0.562   0.241   0.272   0.271
89    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
90    T        -1.052  -1.075  -1.029  -0.971  -1.003  -0.940  -0.851  -0.866  -0.799
91    L        -0.910  -0.908  -0.937  -0.975  -0.980  -1.017  -0.695  -0.690  -0.701
92    D         0.073   0.140   0.077   0.052   0.168   0.064  -0.071   0.034  -0.049
93    L        -0.535  -0.459  -0.517  -0.600  -0.459  -0.570  -0.539  -0.442  -0.492
94    L        -1.052  -1.035  -1.027  -1.115  -1.072  -1.080  -0.851  -0.830  -0.797
95    I        -0.677  -0.633  -0.622  -0.939  -0.873  -0.859  -0.695  -0.651  -0.615
96    E        -1.427  -1.381  -1.387  -1.206  -1.119  -1.148  -1.007  -0.966  -0.943
97    K        -0.535  -0.497  -0.519  -0.534  -0.468  -0.501  -0.539  -0.490  -0.499
98    G        -1.052  -1.087  -1.035  -0.935  -0.972  -0.902  -0.851  -0.876  -0.805
99    V         0.375   0.259   0.152   0.606   0.437   0.269   0.397   0.231   0.073
100   R        -1.052  -1.036  -1.018  -1.014  -0.990  -0.969  -0.851  -0.833  -0.791
101   -         0.642   0.588   0.606   0.627   0.539   0.554   0.410   0.313   0.309
102   -        -0.185  -0.171  -0.115  -0.102  -0.076  -0.006  -0.389  -0.375  -0.306
103   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
104   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
105   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
106   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
107   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
108   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
109   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
110   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
111   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
112   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
113   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
114   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
115   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
116   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
117   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
118   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
119   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
120   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
121   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
122   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
123   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
124   -         0.642   0.677   0.667   0.545   0.606   0.568   0.410   0.462   0.415
125   -        -0.185  -0.128  -0.117  -0.266  -0.181  -0.174  -0.389  -0.318  -0.308
126   -         0.642   0.679   0.668   0.326   0.373   0.344   0.410   0.462   0.417
127   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
128   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
129   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
130   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
131   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
132   -        -0.185  -0.189  -0.121  -0.321  -0.334  -0.247  -0.389  -0.397  -0.314
133   -        -0.785  -0.764  -0.699  -0.968  -0.935  -0.854  -0.789  -0.766  -0.686
134   -         0.010   0.021   0.011  -0.048  -0.035  -0.067  -0.123  -0.110  -0.130
135   -        -1.180  -1.163  -1.105  -0.845  -0.817  -0.726  -0.955  -0.937  -0.864
136   -        -0.679  -0.710  -0.662  -0.733  -0.807  -0.747  -0.678  -0.710  -0.648
137   R         0.375   0.409   0.196   0.472   0.522   0.204   0.397   0.446   0.137
138   N         1.107   1.188   0.952   1.300   1.407   1.088   1.178   1.309   0.910
139   V        -0.910  -0.951  -0.978  -0.843  -0.917  -0.965  -0.695  -0.737  -0.743
140   I         0.073   0.103   0.042  -0.023   0.026  -0.091  -0.071  -0.040  -0.112
141   V         0.375   0.409   0.196   0.553   0.613   0.315   0.397   0.446   0.137
142   N        -0.535  -0.567  -0.559  -0.369  -0.403  -0.370  -0.539  -0.568  -0.545
143   R        -0.160  -0.122  -0.087  -0.191  -0.124  -0.056  -0.383  -0.328  -0.283
144   I        -0.160  -0.157  -0.103  -0.369  -0.344  -0.285  -0.383  -0.378  -0.308
145   L        -0.160  -0.129  -0.105  -0.408  -0.365  -0.320  -0.383  -0.353  -0.310
146   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
147   Y        -1.052  -1.097  -1.050  -0.716  -0.792  -0.706  -0.851  -0.884  -0.818
148   V        -1.052  -1.097  -1.050  -0.969  -1.020  -0.965  -0.851  -0.884  -0.818
149   Y         0.750   0.692   0.659   0.932   0.818   0.793   0.553   0.439   0.374
150   W         2.699   2.729   2.887   3.012   3.061   3.332   3.207   3.264   3.581
151   P        -0.302  -0.244  -0.408  -0.040   0.044  -0.213  -0.227  -0.155  -0.348
152   D        -1.084  -1.064  -1.040  -0.782  -0.753  -0.698  -0.870  -0.848  -0.805
153   G         1.884   1.894   1.802   2.035   2.071   1.946   2.114   2.132   1.936
154   L         1.884   1.814   1.794   1.731   1.650   1.644   2.114   1.986   1.920
155   N         0.375   0.259   0.143   0.582   0.429   0.245   0.397   0.231   0.061
156   V         0.375   0.434   0.207   0.317   0.393   0.083   0.397   0.483   0.154
157   F        -0.535  -0.560  -0.561  -0.604  -0.631  -0.602  -0.539  -0.567  -0.548
158   Q         2.699   2.729   2.887   2.867   2.916   3.179   3.207   3.264   3.581
159   L         1.482   1.479   1.496   1.096   1.088   1.065   1.334   1.316   1.272
160   A         1.267   1.321   1.409   1.041   1.135   1.248   0.866   0.970   1.070
161   E         0.750   0.755   0.722   0.890   0.916   0.864   0.553   0.573   0.491
162   I        -0.019   0.015   0.003  -0.347  -0.308  -0.314  -0.227  -0.186  -0.180
163   D         1.884   1.814   1.794   2.003   1.913   1.908   2.114   1.986   1.920
164   C         1.199   1.229   1.354   1.045   1.080   1.257   0.710   0.760   0.942
165   H        -0.535  -0.543  -0.555  -0.281  -0.313  -0.310  -0.539  -0.548  -0.541
166   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
167   L        -0.302  -0.411  -0.473  -0.349  -0.509  -0.597  -0.227  -0.361  -0.428
168   M        -0.160  -0.089  -0.084  -0.491  -0.397  -0.368  -0.383  -0.296  -0.278
169   I        -1.427  -1.451  -1.420  -1.141  -1.177  -1.126  -1.007  -1.023  -0.969
170   S        -0.535  -0.553  -0.555  -0.392  -0.410  -0.398  -0.539  -0.557  -0.542
171   K        -0.535  -0.589  -0.543  -0.455  -0.517  -0.455  -0.539  -0.586  -0.526
172   P         0.375   0.347   0.204   0.668   0.633   0.427   0.397   0.354   0.150
173   E        -1.052  -1.087  -1.035  -0.984  -1.034  -0.955  -0.851  -0.876  -0.805
174   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
175   K        -1.052  -1.019  -1.032  -0.937  -0.902  -0.909  -0.851  -0.815  -0.802
176   F        -1.052  -1.063  -1.018  -0.764  -0.781  -0.708  -0.851  -0.856  -0.790
177   K        -1.052  -1.054  -1.016  -0.988  -0.996  -0.920  -0.851  -0.849  -0.789
178   W         2.699   2.729   2.887   3.012   3.061   3.332   3.207   3.264   3.581
179   L        -1.427  -1.451  -1.420  -1.462  -1.484  -1.478  -1.007  -1.023  -0.969
180   P        -0.535  -0.429  -0.512  -0.430  -0.271  -0.405  -0.539  -0.419  -0.494
181   S         1.107   1.091   0.928   1.198   1.185   0.962   1.178   1.151   0.870
182   K        -0.160  -0.159  -0.123  -0.254  -0.276  -0.207  -0.383  -0.387  -0.333
183   A        -0.302  -0.291  -0.428  -0.060  -0.046  -0.259  -0.227  -0.213  -0.372
184   L        -0.535  -0.553  -0.537  -0.618  -0.627  -0.599  -0.539  -0.556  -0.519
185   R        -0.302  -0.346  -0.444  -0.024  -0.089  -0.224  -0.227  -0.283  -0.393
186   G        -0.535  -0.501  -0.519  -0.515  -0.482  -0.505  -0.539  -0.490  -0.494
187   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
188   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
189   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
190   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
191   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
192   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
193   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
194   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
195   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
196   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
197   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
198   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
199   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
200   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
201   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
202   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
203   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
204   D        -0.910  -0.949  -0.949  -0.645  -0.726  -0.700  -0.695  -0.735  -0.714
205   G         0.073   0.133   0.027   0.113   0.179   0.030  -0.071  -0.021  -0.131
206   K         1.107   1.091   0.928   1.188   1.173   0.950   1.178   1.151   0.870
207   P        -1.427  -1.429  -1.391  -1.334  -1.347  -1.292  -1.007  -1.006  -0.946
208   Y        -0.302  -0.263  -0.428  -0.040   0.014  -0.232  -0.227  -0.177  -0.373
209   V        -0.677  -0.685  -0.625  -0.810  -0.838  -0.758  -0.695  -0.696  -0.617
210   V        -0.019   0.043   0.001  -0.008   0.081   0.040  -0.227  -0.154  -0.184
211   K        -1.084  -1.087  -1.045  -1.245  -1.237  -1.215  -0.870  -0.871  -0.810
212   L        -0.494  -0.514  -0.521  -0.556  -0.571  -0.586  -0.463  -0.487  -0.486
213   Q        -0.302  -0.312  -0.436  -0.061  -0.068  -0.255  -0.227  -0.240  -0.383
214   P         1.884   1.893   1.801   2.061   2.083   1.973   2.114   2.131   1.933
215   A        -1.427  -1.439  -1.398  -1.439  -1.490  -1.411  -1.007  -1.013  -0.951
216   K        -0.160  -0.175  -0.096  -0.317  -0.329  -0.223  -0.383  -0.389  -0.295
217   F         1.107   1.100   0.912   1.378   1.374   1.079   1.178   1.167   0.842
218   I         0.073   0.101   0.023  -0.200  -0.155  -0.275  -0.071  -0.029  -0.134
219   E        -1.052  -1.031  -1.011  -1.059  -1.031  -1.007  -0.851  -0.829  -0.784
220   N        -0.910  -0.916  -0.934  -0.739  -0.773  -0.787  -0.695  -0.701  -0.699
221   L         1.482   1.488   1.483   1.199   1.205   1.191   1.334   1.334   1.243
222   Q        -1.052  -1.002  -1.007  -0.935  -0.881  -0.868  -0.851  -0.805  -0.781
223   T        -1.052  -1.063  -1.032  -1.059  -1.075  -1.023  -0.851  -0.856  -0.802
224   D        -0.535  -0.485  -0.528  -0.426  -0.360  -0.406  -0.539  -0.489  -0.513
225   L         0.375   0.322   0.167   0.307   0.236   0.008   0.397   0.322   0.096
226   A        -1.802  -1.784  -1.746  -1.539  -1.515  -1.455  -1.164  -1.146  -1.086
227   K        -0.677  -0.638  -0.622  -0.886  -0.820  -0.817  -0.695  -0.658  -0.615
228   I         0.073   0.024   0.005  -0.207  -0.282  -0.316  -0.071  -0.138  -0.163
229   Y         0.750   0.676   0.661   0.941   0.822   0.801   0.553   0.424   0.375
230   H        -1.084  -1.087  -1.045  -1.095  -1.125  -1.025  -0.870  -0.871  -0.810
231   C        -0.656  -0.667  -0.613  -0.539  -0.565  -0.487  -0.667  -0.674  -0.601
232   H         0.630   0.668   0.662   0.796   0.866   0.856   0.353   0.427   0.392
233   V         0.073   0.110   0.075   0.147   0.231   0.186  -0.071  -0.005  -0.052
234   Y         0.073   0.065   0.011   0.298   0.275   0.212  -0.071  -0.090  -0.155
235   M        -1.052  -1.041  -1.016  -0.953  -0.933  -0.892  -0.851  -0.838  -0.788
236   F        -0.910  -0.967  -0.982  -0.347  -0.456  -0.461  -0.695  -0.753  -0.748
237   K        -0.160  -0.134  -0.099  -0.293  -0.262  -0.205  -0.383  -0.353  -0.302
238   H         1.107   1.028   0.901   1.507   1.408   1.242   1.178   1.048   0.822
239   P         0.073   0.042  -0.002   0.184   0.106   0.066  -0.071  -0.129  -0.171
240   S        -1.427  -1.439  -1.398  -1.312  -1.334  -1.286  -1.007  -1.013  -0.951
241   L         1.107   1.110   0.945   1.001   0.999   0.786   1.178   1.177   0.899
242   P         1.811   1.799   1.734   1.958   1.943   1.856   1.984   1.958   1.794
243   V        -0.160  -0.159  -0.114  -0.404  -0.403  -0.354  -0.383  -0.381  -0.321
244   L        -0.535  -0.597  -0.571  -0.654  -0.717  -0.693  -0.539  -0.598  -0.555
245   I         0.375   0.347   0.208   0.441   0.415   0.169   0.397   0.354   0.156
246   T        -0.535  -0.519  -0.555  -0.623  -0.603  -0.650  -0.539  -0.523  -0.542
247   R         1.884   1.814   1.794   2.062   1.973   1.987   2.114   1.986   1.920
248   I         0.750   0.679   0.674   0.681   0.590   0.557   0.553   0.443   0.400
249   Q         0.375   0.259   0.152   0.719   0.555   0.387   0.397   0.231   0.073
250   L        -1.052  -1.087  -1.041  -1.184  -1.242  -1.185  -0.851  -0.876  -0.810
251   F         0.750   0.724   0.685   0.882   0.841   0.756   0.553   0.515   0.418
252   D         1.107   1.028   0.901   1.280   1.170   0.994   1.178   1.048   0.822
253   S         0.073   0.139   0.072  -0.110   0.018  -0.093  -0.071   0.034  -0.056
254   N        -0.656  -0.639  -0.612  -0.562  -0.543  -0.483  -0.667  -0.646  -0.600
255   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
256   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
257   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
258   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
259   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
260   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
261   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
262   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
263   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
264   G        -0.185  -0.193  -0.131  -0.164  -0.172  -0.087  -0.389  -0.403  -0.327
265   S        -0.185  -0.182  -0.115  -0.327  -0.323  -0.232  -0.389  -0.388  -0.306
266   I         1.242   1.298   1.399   0.636   0.727   0.853   0.809   0.918   1.047
267   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
268   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
269   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
270   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
271   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
272   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
273   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
274   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
275   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
276   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
277   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
278   N         0.821   0.793   0.727   0.852   0.816   0.690   0.710   0.657   0.520
279   K        -0.679  -0.673  -0.649  -0.700  -0.698  -0.650  -0.678  -0.673  -0.634
280   L        -0.179  -0.179  -0.124  -0.477  -0.483  -0.377  -0.400  -0.400  -0.327
281   D        -0.679  -0.687  -0.633  -0.841  -0.891  -0.809  -0.678  -0.688  -0.616
282   K         0.010   0.059  -0.009  -0.238  -0.167  -0.326  -0.123  -0.061  -0.158
283   F        -0.679  -0.660  -0.626  -0.439  -0.407  -0.353  -0.678  -0.657  -0.608
284   Q        -1.180  -1.154  -1.105  -1.104  -1.053  -0.998  -0.955  -0.930  -0.864
285   G        -0.679  -0.652  -0.626  -0.687  -0.645  -0.623  -0.678  -0.647  -0.608
286   K        -0.227  -0.188  -0.147  -0.377  -0.319  -0.271  -0.463  -0.418  -0.359
287   P        -0.494  -0.501  -0.549  -0.137  -0.158  -0.231  -0.463  -0.470  -0.519
288   L        -0.019  -0.040  -0.026  -0.336  -0.356  -0.332  -0.227  -0.245  -0.214
289   I        -0.910  -0.953  -0.960  -0.789  -0.845  -0.874  -0.695  -0.739  -0.725
290   S         0.750   0.725   0.673   0.662   0.614   0.533   0.553   0.502   0.396
291   R        -0.535  -0.597  -0.570  -0.440  -0.557  -0.540  -0.539  -0.598  -0.554
292   R         1.221   1.249   1.355   0.842   0.880   1.032   0.760   0.805   0.945
293   P         0.975   0.964   0.840   1.190   1.167   1.004   0.964   0.941   0.716
294   Y         0.375   0.322   0.167   0.714   0.637   0.394   0.397   0.322   0.096
295   Y         1.267   1.296   1.400   1.234   1.279   1.437   0.866   0.913   1.051
296   V        -0.535  -0.567  -0.541  -0.661  -0.707  -0.658  -0.539  -0.569  -0.525
297   A         0.073   0.062   0.041   0.164   0.132   0.108  -0.071  -0.088  -0.112
298   F         0.448   0.471   0.510   0.370   0.409   0.428   0.085   0.116   0.143
299   P        -0.302  -0.315  -0.398   0.045   0.016  -0.083  -0.227  -0.245  -0.336
300   L        -1.802  -1.784  -1.746  -1.414  -1.369  -1.324  -1.164  -1.146  -1.086
301   N        -0.302  -0.411  -0.473   0.017  -0.122  -0.199  -0.227  -0.361  -0.428
302   S         0.750   0.720   0.680   0.696   0.642   0.593   0.553   0.492   0.408
303   P         1.107   1.028   0.901   1.360   1.258   1.084   1.178   1.048   0.822
304   I        -0.535  -0.587  -0.567  -0.235  -0.295  -0.258  -0.539  -0.589  -0.553
305   I         0.750   0.710   0.703   0.694   0.663   0.623   0.553   0.500   0.448
306   F        -0.160  -0.133  -0.109  -0.187  -0.143  -0.098  -0.383  -0.360  -0.314
307   H         1.107   0.992   0.887   1.501   1.351   1.208   1.178   0.990   0.798
308   S         1.107   1.027   0.908   1.146   1.038   0.846   1.178   1.047   0.835
309   V        -1.427  -1.404  -1.390  -1.416  -1.391  -1.388  -1.007  -0.984  -0.945
310   D        -1.513  -1.494  -1.449  -1.192  -1.150  -1.090  -1.074  -1.055  -0.991
311   K        -0.494  -0.548  -0.563  -0.433  -0.513  -0.569  -0.463  -0.528  -0.536
312   D         0.975   0.877   0.801   1.087   0.934   0.815   0.964   0.800   0.649
313   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
314   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
315   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
316   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
317   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
318   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
319   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
320   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
321   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
322   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
323   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
324   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
325   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
326   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
327   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
328   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
329   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
330   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
331   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
332   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
333   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
334   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
335   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
336   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
337   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
339   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
340   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
341   I        -0.910  -0.965  -0.966  -0.694  -0.774  -0.764  -0.695  -0.751  -0.732
342   Y        -0.535  -0.583  -0.555  -0.334  -0.398  -0.352  -0.539  -0.578  -0.535
343   A        -0.302  -0.363  -0.434   0.078  -0.022  -0.099  -0.227  -0.305  -0.380
344   R        -1.427  -1.395  -1.387  -1.129  -1.074  -1.073  -1.007  -0.978  -0.942
345   L        -0.535  -0.544  -0.533  -0.676  -0.667  -0.639  -0.539  -0.537  -0.510
346   V         0.073  -0.013  -0.002   0.060  -0.066  -0.082  -0.071  -0.179  -0.170
347   L         0.375   0.372   0.227   0.356   0.337   0.168   0.397   0.389   0.184
348   Q        -1.427  -1.450  -1.399  -1.163  -1.209  -1.132  -1.007  -1.022  -0.952
349   S         0.073   0.044   0.010   0.200   0.142   0.106  -0.071  -0.113  -0.157
350   I        -0.160  -0.176  -0.109  -0.237  -0.245  -0.151  -0.383  -0.392  -0.314
351   S        -0.535  -0.603  -0.570  -0.624  -0.745  -0.703  -0.539  -0.605  -0.556
352   R         0.375   0.322   0.167   0.639   0.557   0.342   0.397   0.322   0.096
353   T        -1.427  -1.421  -1.387  -1.368  -1.364  -1.316  -1.007  -0.999  -0.942
354   I        -0.019  -0.020  -0.001  -0.314  -0.306  -0.271  -0.227  -0.225  -0.186
355   S         0.630   0.656   0.663   0.492   0.541   0.547   0.353   0.409   0.394
356   E        -0.679  -0.704  -0.662  -0.513  -0.570  -0.500  -0.678  -0.705  -0.648
357   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
358   R         0.010   0.063  -0.009   0.048   0.120  -0.006  -0.123  -0.052  -0.158
359   E        -0.656  -0.623  -0.606  -0.701  -0.656  -0.623  -0.667  -0.633  -0.595
360   T        -0.227  -0.193  -0.147  -0.315  -0.281  -0.198  -0.463  -0.426  -0.360
361   I         0.630   0.633   0.652   0.485   0.530   0.529   0.353   0.374   0.374
362   I        -0.656  -0.702  -0.642  -0.847  -0.874  -0.798  -0.667  -0.707  -0.630
363   F         1.811   1.890   1.752   1.650   1.762   1.591   1.984   2.125   1.832
364   K        -0.065  -0.043  -0.039  -0.227  -0.202  -0.190  -0.259  -0.235  -0.221
365   P        -0.227  -0.201  -0.147  -0.511  -0.462  -0.375  -0.463  -0.432  -0.358
366   V        -1.084  -1.068  -1.041  -1.139  -1.112  -1.090  -0.870  -0.853  -0.806
367   Q         0.510   0.531   0.541   0.359   0.354   0.387   0.155   0.168   0.177
368   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
369   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
370   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
371   K        -1.052  -1.097  -1.050  -0.944  -1.025  -0.945  -0.851  -0.884  -0.818
372   I        -0.535  -0.437  -0.517  -0.780  -0.642  -0.752  -0.539  -0.425  -0.498
373   P         1.107   0.992   0.887   1.372   1.218   1.081   1.178   0.990   0.798
374   V        -0.160  -0.152  -0.093  -0.312  -0.284  -0.219  -0.383  -0.357  -0.292
375   K        -0.019  -0.003   0.003  -0.207  -0.190  -0.181  -0.227  -0.207  -0.182
376   S         1.267   1.257   1.358   0.921   0.896   1.023   0.866   0.824   0.950
377   I         0.750   0.808   0.730   0.446   0.550   0.411   0.553   0.659   0.500
378   H        -0.677  -0.672  -0.624  -0.575  -0.571  -0.487  -0.695  -0.686  -0.618
379   N        -0.677  -0.632  -0.620  -0.812  -0.742  -0.727  -0.695  -0.650  -0.613
380   I        -0.160  -0.151  -0.084  -0.405  -0.389  -0.295  -0.383  -0.357  -0.275
381   M        -1.052  -1.060  -1.030  -0.847  -0.869  -0.809  -0.851  -0.853  -0.800
382   T        -0.019  -0.038  -0.012  -0.198  -0.215  -0.189  -0.227  -0.242  -0.197
383   L        -0.910  -0.986  -0.986  -1.046  -1.161  -1.176  -0.695  -0.771  -0.752
384   L        -0.910  -0.898  -0.939  -0.944  -0.944  -0.983  -0.695  -0.684  -0.704
385   G         1.884   1.893   1.801   2.035   2.070   1.945   2.114   2.131   1.933
386   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
387   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
388   P        -0.535  -0.548  -0.552  -0.359  -0.385  -0.367  -0.539  -0.550  -0.538
389   S         0.590   0.563   0.620   0.340   0.308   0.390   0.241   0.203   0.280
390   R         1.107   1.028   0.901   1.308   1.191   1.019   1.178   1.048   0.822
391   F        -1.427  -1.450  -1.399  -1.120  -1.164  -1.087  -1.007  -1.022  -0.952
392   A        -0.019  -0.002  -0.007  -0.018   0.010   0.013  -0.227  -0.204  -0.192
393   E        -0.535  -0.508  -0.556  -0.493  -0.456  -0.528  -0.539  -0.513  -0.542
394   S         0.590   0.583   0.611   0.406   0.396   0.457   0.241   0.223   0.267
395   M        -0.019  -0.042  -0.029  -0.097  -0.126  -0.076  -0.227  -0.248  -0.217
396   G         2.699   2.729   2.887   2.778   2.840   3.085   3.207   3.264   3.581
397   P        -0.910  -0.952  -0.976  -0.728  -0.781  -0.821  -0.695  -0.737  -0.742
398   W         2.699   2.729   2.887   3.012   3.061   3.332   3.207   3.264   3.581
399   E         0.073   0.108   0.075   0.043   0.109   0.063  -0.071  -0.010  -0.053
400   C        -0.677  -0.631  -0.625  -0.651  -0.600  -0.565  -0.695  -0.648  -0.617
401   Y         1.884   1.893   1.801   2.181   2.202   2.120   2.114   2.131   1.933
402   A         1.884   1.894   1.802   2.074   2.086   1.986   2.114   2.132   1.936
403   S        -0.910  -0.931  -0.968  -0.765  -0.809  -0.882  -0.695  -0.715  -0.734
404   A        -0.535  -0.584  -0.537  -0.456  -0.516  -0.465  -0.539  -0.580  -0.519
405   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
406   N        -1.427  -1.451  -1.420  -1.186  -1.252  -1.181  -1.007  -1.023  -0.969
407   F         0.375   0.376   0.190   0.592   0.586   0.309   0.397   0.398   0.129
408   E         1.267   1.302   1.390   1.007   1.061   1.174   0.866   0.928   1.026
409   R        -1.052  -1.061  -1.029  -0.765  -0.801  -0.733  -0.851  -0.853  -0.799
410   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
411   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
412   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
413   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
414   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
415   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
416   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
417   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
418   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
419   S         0.448   0.501   0.551   0.064   0.161   0.203   0.085   0.165   0.211
420   P         2.699   2.729   2.887   2.802   2.850   3.110   3.207   3.264   3.581
421   L         1.884   1.923   1.816   1.731   1.787   1.675   2.114   2.186   1.965
422   H        -0.535  -0.535  -0.565  -0.403  -0.417  -0.439  -0.539  -0.545  -0.552
423   D        -1.052  -0.997  -1.026  -0.833  -0.771  -0.775  -0.851  -0.799  -0.797
424   Y        -0.227  -0.185  -0.147  -0.340  -0.280  -0.216  -0.463  -0.416  -0.359
425   K         0.525   0.498   0.573   0.159   0.112   0.203   0.149   0.118   0.219
426   K        -0.065  -0.088  -0.046  -0.250  -0.283  -0.230  -0.259  -0.285  -0.230
427   H         0.375   0.259   0.152   0.784   0.611   0.449   0.397   0.231   0.073
428   Q         0.073   0.198   0.080   0.199   0.389   0.217  -0.071   0.104  -0.055
429   G        -1.084  -1.005  -1.031  -1.191  -1.038  -1.128  -0.870  -0.792  -0.796
430   L         0.202   0.264   0.121   0.098   0.178  -0.012   0.149   0.237   0.029
431   T        -0.179  -0.100  -0.114  -0.393  -0.280  -0.296  -0.400  -0.306  -0.315
432   G         0.416   0.457   0.502   0.138   0.200   0.250   0.010   0.065   0.119
433   K         0.416   0.443   0.508   0.054   0.091   0.182   0.010   0.049   0.127
434   K        -0.785  -0.759  -0.699  -0.907  -0.889  -0.791  -0.789  -0.760  -0.686
435   V         0.642   0.677   0.618   0.533   0.587   0.457   0.410   0.464   0.329
436   M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
437   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
438   R        -0.185  -0.169  -0.146  -0.168  -0.141  -0.127  -0.389  -0.373  -0.347
439   E         0.642   0.583   0.596   0.563   0.458   0.443   0.410   0.304   0.292
440   F        -0.785  -0.764  -0.699  -1.031  -1.031  -0.921  -0.789  -0.766  -0.686
441   D        -0.785  -0.764  -0.699  -0.839  -0.820  -0.719  -0.789  -0.766  -0.686
442   D         1.616   1.676   1.608   1.635   1.722   1.610   1.609   1.720   1.524
443   S        -0.185  -0.128  -0.131  -0.455  -0.376  -0.407  -0.389  -0.314  -0.327
444   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
445   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
446   N        -0.185  -0.149  -0.120  -0.361  -0.311  -0.291  -0.389  -0.345  -0.312
447   D         2.699   2.729   2.887   2.746   2.788   3.052   3.207   3.264   3.581
448   D        -0.179  -0.156  -0.124  -0.284  -0.253  -0.200  -0.400  -0.372  -0.327
449   E        -0.185  -0.218  -0.160  -0.440  -0.532  -0.472  -0.389  -0.438  -0.366
450   N         0.416   0.374   0.503   0.126   0.053   0.240   0.010  -0.049   0.120
451   F        -0.185  -0.113  -0.112  -0.579  -0.471  -0.492  -0.389  -0.295  -0.302
452   Y        -0.785  -0.754  -0.699  -0.888  -0.853  -0.771  -0.789  -0.756  -0.686
453   G        -0.179  -0.189  -0.126  -0.458  -0.434  -0.357  -0.400  -0.408  -0.329
454   K        -0.679  -0.701  -0.636  -0.675  -0.715  -0.606  -0.678  -0.702  -0.620
455   E        -0.679  -0.673  -0.649  -0.784  -0.778  -0.763  -0.678  -0.673  -0.634
456   E        -0.179  -0.185  -0.125  -0.504  -0.496  -0.408  -0.400  -0.405  -0.327
457   P        -0.494  -0.524  -0.548  -0.404  -0.449  -0.477  -0.463  -0.499  -0.518
458   E        -0.656  -0.634  -0.602  -0.744  -0.720  -0.666  -0.667  -0.644  -0.591
459   I        -0.494  -0.573  -0.567  -0.359  -0.457  -0.457  -0.463  -0.556  -0.541
460   R        -0.910  -0.951  -0.978  -0.604  -0.682  -0.716  -0.695  -0.737  -0.743
461   R         0.590   0.550   0.614   0.408   0.359   0.446   0.241   0.196   0.278
462   L         0.073  -0.008  -0.011  -0.174  -0.290  -0.289  -0.071  -0.181  -0.184
463   R         1.107   1.063   0.905   1.317   1.253   1.039   1.178   1.107   0.828
464   L        -0.179  -0.188  -0.122  -0.530  -0.536  -0.449  -0.400  -0.409  -0.325
465   E        -1.180  -1.164  -1.105  -0.972  -0.939  -0.859  -0.955  -0.938  -0.864
466   K        -0.179  -0.188  -0.122  -0.356  -0.366  -0.275  -0.400  -0.409  -0.325
467   N        -0.179  -0.168  -0.117  -0.331  -0.312  -0.249  -0.400  -0.385  -0.318
468   M         0.010  -0.030  -0.029   0.245   0.177   0.165  -0.123  -0.180  -0.187
469   I        -0.679  -0.698  -0.649  -0.863  -0.898  -0.856  -0.678  -0.697  -0.634
470   K         1.199   1.222   1.344   0.828   0.862   1.038   0.710   0.743   0.916
471   F         1.884   1.854   1.801   2.117   2.083   2.012   2.114   2.059   1.933
472   K         0.375   0.259   0.152   0.496   0.336   0.171   0.397   0.231   0.073
473   G         0.375   0.259   0.152   0.621   0.465   0.282   0.397   0.231   0.073
474   S         0.375   0.259   0.152   0.487   0.321   0.152   0.397   0.231   0.073
475   A        -0.679  -0.665  -0.628  -0.784  -0.736  -0.716  -0.678  -0.663  -0.610
476   N         0.510   0.532   0.551   0.248   0.254   0.289   0.155   0.165   0.192
477   G         1.724   1.621   1.659   1.870   1.741   1.790   1.819   1.610   1.634
478   V         0.010   0.129   0.010  -0.034   0.172  -0.077  -0.123   0.045  -0.132
479   M        -0.679  -0.632  -0.626  -0.930  -0.870  -0.860  -0.678  -0.624  -0.608
480   D        -0.679  -0.618  -0.618  -0.575  -0.488  -0.483  -0.678  -0.609  -0.599
481   Q        -0.179  -0.204  -0.137  -0.339  -0.381  -0.287  -0.400  -0.427  -0.341
482   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
483   K         0.202   0.131   0.083   0.145   0.020  -0.090   0.149   0.048  -0.026
484   Y         0.525   0.582   0.591   0.089   0.158   0.189   0.149   0.220   0.241
485   N        -1.084  -1.092  -1.049  -0.874  -0.898  -0.832  -0.870  -0.875  -0.813
486   D         0.321   0.341   0.440   0.048   0.066   0.217  -0.123  -0.097   0.026
487   L        -1.180  -1.157  -1.105  -1.273  -1.203  -1.176  -0.955  -0.932  -0.864
488   K         0.821   0.787   0.737   0.770   0.722   0.633   0.710   0.643   0.536
489   E         0.510   0.477   0.539   0.248   0.174   0.261   0.155   0.097   0.174
490   F        -0.679  -0.639  -0.626  -0.571  -0.515  -0.493  -0.678  -0.632  -0.608
491   N        -0.679  -0.653  -0.636  -0.708  -0.677  -0.655  -0.678  -0.650  -0.619
492   E        -0.179  -0.112  -0.112  -0.335  -0.243  -0.243  -0.400  -0.324  -0.313
493   H        -0.179  -0.117  -0.112  -0.193  -0.115  -0.106  -0.400  -0.326  -0.313
494   V         0.010   0.029  -0.029   0.058   0.083  -0.038  -0.123  -0.102  -0.187
495   H        -0.179  -0.113  -0.112  -0.023   0.062   0.088  -0.400  -0.325  -0.313
496   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
497   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
498   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
499   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
500   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
501   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
502   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
503   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
504   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
505   N         1.724   1.621   1.659   1.740   1.597   1.649   1.819   1.610   1.634
506   I         1.724   1.795   1.685   1.459   1.561   1.379   1.819   1.951   1.691
507   R        -0.679  -0.623  -0.619  -0.770  -0.688  -0.700  -0.678  -0.614  -0.600
508   N        -0.679  -0.680  -0.632  -0.582  -0.572  -0.524  -0.678  -0.681  -0.614
509   G        -0.785  -0.754  -0.699  -0.899  -0.845  -0.782  -0.789  -0.756  -0.686
510   K        -0.785  -0.754  -0.699  -0.809  -0.748  -0.688  -0.789  -0.756  -0.686
511   K        -0.785  -0.754  -0.699  -1.002  -0.978  -0.891  -0.789  -0.756  -0.686
512   N         1.242   1.270   1.371   0.896   0.944   1.068   0.809   0.853   0.980
513   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
514   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
515   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
516   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
517   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
518   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
519   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
520   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
521   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
522   I        -1.084  -1.068  -1.049  -1.144  -1.116  -1.106  -0.870  -0.855  -0.813
523   S        -0.656  -0.669  -0.620  -0.837  -0.875  -0.807  -0.667  -0.678  -0.608
524   R        -0.656  -0.679  -0.628  -0.712  -0.747  -0.668  -0.667  -0.686  -0.616
525   Y         0.630   0.620   0.652   0.742   0.738   0.784   0.353   0.356   0.374
526   S        -0.656  -0.681  -0.613  -0.653  -0.703  -0.594  -0.667  -0.688  -0.601
527   S         2.699   2.729   2.887   2.646   2.694   2.946   3.207   3.264   3.581
528   L        -0.494  -0.494  -0.542  -0.657  -0.650  -0.736  -0.463  -0.467  -0.511
529   V        -0.227  -0.179  -0.146  -0.529  -0.477  -0.433  -0.463  -0.408  -0.357
530   P         2.699   2.729   2.887   2.817   2.867   3.126   3.207   3.264   3.581
531   I        -0.535  -0.583  -0.566  -0.442  -0.504  -0.455  -0.539  -0.591  -0.554
532   E        -1.052  -1.061  -1.029  -0.926  -0.952  -0.906  -0.851  -0.853  -0.799
533   K        -0.065  -0.075  -0.049  -0.073  -0.081  -0.029  -0.259  -0.259  -0.226
534   V         0.525   0.588   0.588   0.383   0.454   0.478   0.149   0.226   0.237
535   G        -0.494  -0.510  -0.558  -0.356  -0.392  -0.463  -0.463  -0.483  -0.530
536   F         1.811   1.851   1.747   2.090   2.153   2.039   1.984   2.054   1.821
537   T        -0.065  -0.102  -0.065  -0.116  -0.160  -0.107  -0.259  -0.293  -0.247
538   L        -0.656  -0.679  -0.612  -0.876  -0.883  -0.806  -0.667  -0.685  -0.600
539   K         0.525   0.528   0.581   0.266   0.285   0.364   0.149   0.160   0.231
540   N        -0.656  -0.673  -0.621  -0.662  -0.693  -0.607  -0.667  -0.680  -0.609
541   E        -0.679  -0.700  -0.636  -0.730  -0.776  -0.682  -0.678  -0.701  -0.620
542   I        -0.679  -0.700  -0.636  -0.816  -0.840  -0.767  -0.678  -0.701  -0.620
543   N        -1.180  -1.157  -1.105  -0.944  -0.892  -0.829  -0.955  -0.932  -0.864
544   S        -0.679  -0.680  -0.649  -0.748  -0.779  -0.713  -0.678  -0.680  -0.634
545   R         0.010   0.137   0.018   0.038   0.250   0.032  -0.123   0.057  -0.120
546   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
547   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
548   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
549   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
550   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
551   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
552   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
553   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
554   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
555   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
556   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
557   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
558   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
559   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
560   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
561   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
562   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
563   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
564   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
565   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
566   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
567   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
568   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
569   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
570   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
571   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
572   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
573   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
574   -        -0.179  -0.203  -0.116  -0.139  -0.150  -0.030  -0.400  -0.425  -0.318
575   -         0.510   0.583   0.581   0.353   0.438   0.456   0.155   0.248   0.242
576   -        -0.679  -0.614  -0.623  -0.622  -0.513  -0.547  -0.678  -0.604  -0.605
577   T        -1.052  -1.020  -1.010  -1.171  -1.150  -1.127  -0.851  -0.821  -0.784
578   I         1.267   1.252   1.356   0.960   0.931   1.066   0.866   0.812   0.947
579   K        -0.535  -0.561  -0.530  -0.544  -0.577  -0.531  -0.539  -0.561  -0.514
580   L         0.073   0.108   0.038  -0.063  -0.022  -0.095  -0.071  -0.031  -0.116
581   K        -0.302  -0.411  -0.473  -0.150  -0.305  -0.401  -0.227  -0.361  -0.428
582   F         0.073   0.114   0.045  -0.078  -0.020  -0.101  -0.071  -0.020  -0.107
583   N        -1.427  -1.429  -1.392  -1.270  -1.264  -1.215  -1.007  -1.006  -0.946
584   G         2.699   2.729   2.887   2.778   2.840   3.085   3.207   3.264   3.581
585   N        -1.052  -1.054  -1.025  -1.132  -1.112  -1.109  -0.851  -0.849  -0.796
586   D         1.482   1.424   1.470   1.482   1.383   1.450   1.334   1.197   1.214
587   I         1.199   1.221   1.343   0.839   0.877   1.045   0.710   0.742   0.915
588   F         1.107   1.027   0.908   1.417   1.302   1.137   1.178   1.047   0.835
589   G         0.590   0.543   0.618   0.507   0.452   0.558   0.241   0.183   0.279
590   G         2.699   2.729   2.887   2.778   2.840   3.085   3.207   3.264   3.581
591   L         1.107   1.063   0.905   0.978   0.922   0.688   1.178   1.107   0.828
592   H         0.375   0.259   0.152   0.800   0.626   0.473   0.397   0.231   0.073
593   E         0.375   0.259   0.152   0.592   0.426   0.277   0.397   0.231   0.073
594   L         0.750   0.745   0.708   0.459   0.452   0.391   0.553   0.540   0.458
595   C        -0.019  -0.040  -0.026   0.086   0.074   0.113  -0.227  -0.245  -0.214
596   D        -0.910  -0.915  -0.963  -0.633  -0.660  -0.706  -0.695  -0.701  -0.728
597   K         0.073  -0.014  -0.000   0.059  -0.059  -0.037  -0.071  -0.179  -0.169
598   N        -0.535  -0.484  -0.521  -0.487  -0.394  -0.462  -0.539  -0.479  -0.499
599   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
600   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
601   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
602   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
603   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
604   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
605   L        -0.019  -0.062  -0.032  -0.354  -0.402  -0.361  -0.227  -0.271  -0.221
606   I         0.590   0.563   0.618   0.175   0.136   0.195   0.241   0.203   0.278
607   N         1.267   1.314   1.388   1.009   1.090   1.173   0.866   0.953   1.022
608   I         0.073   0.063   0.021   0.122   0.127   0.042  -0.071  -0.074  -0.132
609   D        -0.910  -0.896  -0.930  -0.654  -0.640  -0.676  -0.695  -0.680  -0.694
610   K        -1.052  -1.040  -1.016  -0.933  -0.921  -0.868  -0.851  -0.836  -0.788
611   V         0.750   0.886   0.760   0.930   1.141   0.946   0.553   0.773   0.551
612   P         2.699   2.729   2.887   2.802   2.850   3.110   3.207   3.264   3.581
613   G        -0.910  -0.894  -0.945  -0.600  -0.588  -0.648  -0.695  -0.678  -0.710
614   W         1.884   1.814   1.794   2.303   2.224   2.237   2.114   1.986   1.920
615   L         1.884   1.893   1.801   1.740   1.759   1.669   2.114   2.131   1.933
616   A         1.107   1.160   0.936   1.389   1.459   1.202   1.178   1.264   0.883
617   G         2.699   2.729   2.887   2.778   2.840   3.085   3.207   3.264   3.581
618   E         1.884   1.894   1.802   1.981   2.002   1.899   2.114   2.132   1.936
619   N         0.073   0.036   0.022   0.101   0.061   0.039  -0.071  -0.109  -0.132
620   G         1.884   1.893   1.801   2.035   2.070   1.945   2.114   2.131   1.933
621   S        -1.052  -1.067  -1.019  -1.057  -1.119  -1.022  -0.851  -0.860  -0.791
622   F         0.590   0.633   0.618   0.401   0.445   0.464   0.241   0.287   0.278
623   S         0.073   0.089   0.027   0.040   0.047  -0.018  -0.071  -0.059  -0.133
624   G         1.884   1.814   1.794   2.008   1.929   1.887   2.114   1.986   1.920
625   T        -1.802  -1.784  -1.746  -1.551  -1.517  -1.468  -1.164  -1.146  -1.086
626   I         1.199   1.229   1.354   0.839   0.903   1.080   0.710   0.760   0.942
627   M        -0.535  -0.489  -0.521  -0.478  -0.406  -0.446  -0.539  -0.479  -0.502
628   N         0.357   0.383   0.465   0.064   0.105   0.214  -0.071  -0.035   0.066
629   G         1.884   1.923   1.816   2.046   2.121   1.987   2.114   2.186   1.965
630   D        -1.802  -1.784  -1.746  -1.728  -1.729  -1.655  -1.164  -1.146  -1.086
631   F         0.375   0.259   0.152   0.752   0.586   0.428   0.397   0.231   0.073
632   Q        -1.427  -1.406  -1.393  -1.288  -1.300  -1.250  -1.007  -0.988  -0.947
633   R        -1.427  -1.406  -1.388  -1.133  -1.092  -1.074  -1.007  -0.988  -0.943
634   E        -1.052  -1.036  -1.016  -0.991  -0.971  -0.944  -0.851  -0.834  -0.788
635   Q        -1.052  -0.991  -1.008  -1.046  -0.940  -0.992  -0.851  -0.795  -0.782
636   V        -0.185  -0.189  -0.131  -0.338  -0.359  -0.288  -0.389  -0.399  -0.327
637   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
638   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
639   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
640   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
641   G         0.642   0.643   0.661   0.625   0.629   0.633   0.410   0.403   0.404
642   G         0.642   0.591   0.624   0.577   0.484   0.505   0.410   0.318   0.340
643   L         0.416   0.421   0.510  -0.108  -0.091   0.022   0.010   0.017   0.131
644   L         0.416   0.404   0.510  -0.109  -0.123   0.010   0.010  -0.007   0.130
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P38907
Output conservation file - output/P38907
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
