1     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    M         1.245   1.404   1.163   1.575   1.799   1.479   1.328   1.586   1.143
33    A         0.825   0.812   0.859   0.666   0.600   0.628   0.557   0.494   0.521
34    S         0.315   0.261   0.194   0.259   0.173   0.096   0.184   0.085  -0.036
35    S         0.753   0.834   0.863   0.385   0.518   0.521   0.410   0.540   0.529
36    S        -0.396  -0.428  -0.431  -0.546  -0.600  -0.619  -0.494  -0.536  -0.535
37    H         0.042   0.130   0.111   0.103   0.245   0.206  -0.268  -0.134  -0.176
38    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    N         0.825   0.773   0.846   0.850   0.757   0.860   0.557   0.412   0.493
44    P         0.148   0.199   0.147   0.030   0.071  -0.020  -0.107  -0.051  -0.125
45    V        -0.997  -0.958  -0.892  -1.240  -1.188  -1.094  -0.960  -0.903  -0.805
46    I        -0.340  -0.403  -0.398  -0.407  -0.558  -0.555  -0.452  -0.536  -0.507
47    L         1.959   2.041   2.143   1.715   1.827   1.999   2.218   2.351   2.538
48    L         1.245   1.224   1.133   1.088   1.067   0.954   1.328   1.286   1.085
49    K        -0.873  -0.900  -0.862  -0.759  -0.783  -0.735  -0.833  -0.846  -0.776
50    R         1.245   1.224   1.133   1.493   1.476   1.356   1.328   1.286   1.085
51    I         0.056   0.119   0.122  -0.351  -0.269  -0.251  -0.273  -0.188  -0.169
52    L         1.182   1.278   1.091   1.010   1.139   0.893   1.221   1.379   1.003
53    S        -0.076  -0.284  -0.323  -0.007  -0.266  -0.325  -0.071  -0.340  -0.396
54    L         1.245   1.135   1.124   1.073   0.923   0.911   1.328   1.126   1.068
55    T        -0.012   0.010   0.077  -0.116  -0.083   0.003  -0.325  -0.307  -0.223
56    E         0.705   0.705   0.814   0.389   0.361   0.527   0.311   0.268   0.421
57    S        -0.873  -0.829  -0.829  -0.991  -0.965  -0.931  -0.833  -0.766  -0.737
58    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
59    S         1.245   1.382   1.153   1.164   1.356   1.056   1.328   1.551   1.124
60    P         0.253   0.315   0.236   0.223   0.348   0.173   0.057   0.169   0.018
61    F         0.645   0.709   0.818   0.216   0.279   0.454   0.184   0.277   0.430
62    I        -0.421  -0.277  -0.376  -0.560  -0.340  -0.480  -0.579  -0.399  -0.484
63    L         0.893   0.831   0.876   0.582   0.456   0.518   0.692   0.535   0.557
64    C        -0.545  -0.532  -0.440  -0.589  -0.599  -0.452  -0.706  -0.660  -0.555
65    L        -0.669  -0.708  -0.781  -0.817  -0.879  -1.025  -0.579  -0.618  -0.680
66    D         1.959   2.041   2.143   1.976   2.098   2.266   2.218   2.351   2.538
67    S         0.112   0.043   0.149  -0.206  -0.276  -0.129  -0.198  -0.271  -0.134
68    I        -0.076   0.037  -0.234  -0.112   0.036  -0.316  -0.071   0.088  -0.277
69    A        -0.873  -0.866  -0.864  -0.874  -0.880  -0.878  -0.833  -0.822  -0.777
70    Q         1.959   2.041   2.143   2.082   2.212   2.375   2.218   2.351   2.538
71    T         0.253   0.180   0.181   0.070  -0.034  -0.044   0.057  -0.055  -0.077
72    S         0.705   0.705   0.814   0.332   0.317   0.485   0.311   0.268   0.421
73    Y        -0.669  -0.810  -0.814  -0.354  -0.576  -0.595  -0.579  -0.730  -0.717
74    K        -1.326  -1.209  -1.240  -1.069  -0.898  -0.928  -1.088  -0.964  -0.949
75    L         0.253   0.297   0.212  -0.027   0.011  -0.099   0.057   0.100  -0.028
76    I        -0.092  -0.013   0.066  -0.518  -0.426  -0.299  -0.452  -0.341  -0.243
77    Q        -0.669  -0.693  -0.771  -0.412  -0.457  -0.605  -0.579  -0.602  -0.670
78    E         1.245   1.135   1.124   1.258   1.127   1.118   1.328   1.126   1.068
79    F         0.253   0.300   0.207   0.343   0.391   0.264   0.057   0.098  -0.036
80    V        -0.545  -0.484  -0.451  -0.800  -0.730  -0.673  -0.706  -0.638  -0.572
81    H        -0.669  -0.714  -0.780  -0.251  -0.331  -0.439  -0.579  -0.628  -0.679
82    Q        -0.873  -0.780  -0.828  -0.625  -0.490  -0.537  -0.833  -0.726  -0.742
83    S        -1.326  -1.234  -1.237  -1.070  -0.944  -0.968  -1.088  -0.985  -0.947
84    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
85    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
86    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
87    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
88    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
89    K        -0.040  -0.049   0.080  -0.332  -0.347  -0.152  -0.386  -0.392  -0.223
90    G        -0.979  -0.984  -0.888  -1.042  -1.106  -0.929  -0.937  -0.924  -0.800
91    N        -1.654  -1.655  -1.571  -1.521  -1.496  -1.428  -1.215  -1.193  -1.080
92    E        -1.326  -1.323  -1.247  -1.343  -1.300  -1.198  -1.088  -1.064  -0.956
93    Y        -1.654  -1.599  -1.549  -1.456  -1.405  -1.283  -1.215  -1.151  -1.063
94    P        -0.340  -0.237  -0.349  -0.261  -0.091  -0.264  -0.452  -0.298  -0.439
95    I         0.893   0.831   0.876   0.810   0.690   0.732   0.692   0.535   0.557
96    V        -0.092   0.016   0.079  -0.501  -0.375  -0.276  -0.452  -0.297  -0.222
97    Y         0.645   0.709   0.818   0.486   0.582   0.745   0.184   0.277   0.430
98    I         0.112   0.201   0.172  -0.077   0.046  -0.006  -0.198  -0.087  -0.104
99    S         0.565   0.632   0.368   0.547   0.651   0.280   0.565   0.668   0.243
100   F         0.893   0.831   0.876   0.926   0.808   0.856   0.692   0.535   0.557
101   E         1.245   1.224   1.133   1.236   1.220   1.087   1.328   1.286   1.085
102   T         1.959   2.041   2.143   1.934   2.062   2.223   2.218   2.351   2.538
103   V        -0.873  -0.783  -0.820  -1.031  -0.913  -0.944  -0.833  -0.713  -0.729
104   N        -0.076  -0.284  -0.323   0.161  -0.148  -0.235  -0.071  -0.340  -0.396
105   K         0.565   0.619   0.373   0.771   0.852   0.520   0.565   0.648   0.251
106   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
107   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
108   P         1.245   1.257   1.134   1.401   1.433   1.260   1.328   1.342   1.087
109   S        -0.997  -0.992  -0.892  -1.011  -1.003  -0.838  -0.960  -0.933  -0.806
110   Y        -0.669  -0.786  -0.810  -0.290  -0.451  -0.489  -0.579  -0.707  -0.712
111   C        -0.997  -0.981  -0.895  -0.866  -0.858  -0.722  -0.960  -0.922  -0.808
112   T        -0.873  -0.750  -0.815  -0.903  -0.680  -0.786  -0.833  -0.677  -0.722
113   Q        -1.326  -1.313  -1.243  -1.144  -1.064  -1.017  -1.088  -1.056  -0.952
114   F         1.245   1.257   1.134   1.396   1.423   1.243   1.328   1.342   1.087
115   I         1.245   1.135   1.124   1.276   1.121   1.081   1.328   1.126   1.068
116   D        -0.669  -0.786  -0.810  -0.483  -0.665  -0.718  -0.579  -0.707  -0.712
117   A         0.253   0.334   0.250   0.386   0.514   0.412   0.057   0.201   0.046
118   T        -0.340  -0.433  -0.397  -0.436  -0.552  -0.482  -0.452  -0.557  -0.506
119   Q        -1.202  -1.178  -1.186  -0.948  -0.963  -0.971  -0.960  -0.925  -0.898
120   M        -1.202  -1.093  -1.163  -0.926  -0.732  -0.868  -0.960  -0.842  -0.876
121   D        -1.354  -1.336  -1.263  -1.350  -1.371  -1.229  -1.103  -1.070  -0.967
122   F        -1.326  -1.267  -1.241  -1.276  -1.182  -1.174  -1.088  -1.017  -0.951
123   V        -0.997  -0.923  -0.886  -0.940  -0.848  -0.757  -0.960  -0.878  -0.802
124   H        -0.997  -0.961  -0.890  -0.956  -0.913  -0.782  -0.960  -0.907  -0.804
125   L        -0.076  -0.049  -0.250  -0.202  -0.200  -0.487  -0.071  -0.041  -0.299
126   V        -1.202  -1.253  -1.216  -1.125  -1.265  -1.219  -0.960  -0.996  -0.925
127   K        -0.873  -0.862  -0.829  -0.857  -0.815  -0.787  -0.833  -0.794  -0.740
128   Q        -0.545  -0.472  -0.462  -0.656  -0.591  -0.540  -0.706  -0.625  -0.582
129   I         0.253   0.293   0.205   0.110   0.124  -0.024   0.057   0.087  -0.039
130   I        -1.982  -1.938  -1.848  -1.729  -1.620  -1.535  -1.342  -1.286  -1.170
131   S        -0.340  -0.417  -0.370  -0.472  -0.577  -0.510  -0.452  -0.521  -0.468
132   Y        -0.997  -0.885  -0.893  -1.013  -0.822  -0.856  -0.960  -0.840  -0.807
133   L         0.042   0.022   0.099  -0.265  -0.282  -0.140  -0.268  -0.299  -0.200
134   P        -0.396  -0.472  -0.436  -0.465  -0.629  -0.628  -0.494  -0.588  -0.542
135   A        -1.437  -1.394  -1.296  -1.492  -1.438  -1.291  -1.172  -1.114  -0.993
136   A        -0.561  -0.542  -0.468  -0.513  -0.449  -0.354  -0.720  -0.687  -0.585
137   T        -0.566  -0.554  -0.485  -0.532  -0.511  -0.430  -0.711  -0.691  -0.602
138   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
139   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
140   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
141   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
142   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
143   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
144   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
145   A        -0.603  -0.534  -0.475  -0.700  -0.590  -0.496  -0.771  -0.685  -0.596
146   T        -0.076   0.129  -0.209   0.066   0.366  -0.128  -0.071   0.216  -0.244
147   Q        -1.326  -1.299  -1.231  -1.203  -1.117  -1.058  -1.088  -1.040  -0.943
148   A        -1.202  -1.186  -1.188  -1.130  -1.096  -1.097  -0.960  -0.933  -0.900
149   K        -0.873  -0.809  -0.833  -0.845  -0.743  -0.771  -0.833  -0.751  -0.745
150   K        -0.545  -0.484  -0.451  -0.460  -0.384  -0.298  -0.706  -0.634  -0.571
151   H        -0.873  -0.799  -0.831  -0.573  -0.453  -0.527  -0.833  -0.742  -0.745
152   M        -0.076  -0.052  -0.249  -0.112  -0.107  -0.338  -0.071  -0.045  -0.297
153   V         0.645   0.701   0.813   0.365   0.445   0.614   0.184   0.260   0.420
154   I        -0.340  -0.384  -0.376  -0.346  -0.384  -0.408  -0.452  -0.501  -0.478
155   I        -0.012   0.028   0.082  -0.162  -0.103  -0.038  -0.325  -0.269  -0.215
156   D         1.959   2.041   2.143   1.976   2.098   2.266   2.218   2.351   2.538
157   S         0.705   0.721   0.818   0.294   0.301   0.438   0.311   0.302   0.431
158   L         0.565   0.507   0.354   0.455   0.363   0.160   0.565   0.467   0.221
159   N         1.245   1.257   1.134   1.409   1.448   1.272   1.328   1.342   1.087
160   Y        -0.340  -0.364  -0.400  -0.149  -0.216  -0.229  -0.452  -0.498  -0.509
161   I         0.565   0.602   0.368   0.648   0.699   0.337   0.565   0.619   0.243
162   S        -1.326  -1.282  -1.237  -1.280  -1.263  -1.166  -1.088  -1.033  -0.948
163   T        -0.873  -0.796  -0.835  -0.892  -0.785  -0.858  -0.833  -0.742  -0.750
164   E        -1.326  -1.369  -1.263  -1.297  -1.348  -1.194  -1.088  -1.098  -0.968
165   Y        -0.340  -0.239  -0.365  -0.460  -0.357  -0.506  -0.452  -0.343  -0.467
166   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
167   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
168   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
169   I         0.565   0.533   0.359   0.455   0.405   0.168   0.565   0.503   0.229
170   T        -0.340  -0.344  -0.359  -0.336  -0.311  -0.348  -0.452  -0.426  -0.449
171   R        -1.326  -1.324  -1.248  -1.010  -1.015  -0.904  -1.088  -1.064  -0.956
172   F         1.245   1.257   1.134   1.374   1.397   1.198   1.328   1.342   1.087
173   L        -0.545  -0.500  -0.464  -0.777  -0.715  -0.664  -0.706  -0.656  -0.585
174   S        -0.421  -0.360  -0.379  -0.486  -0.354  -0.376  -0.579  -0.490  -0.488
175   E        -0.076   0.141  -0.205  -0.091   0.222  -0.288  -0.071   0.233  -0.237
176   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
177   I         0.112   0.204   0.162  -0.238  -0.153  -0.191  -0.198  -0.097  -0.120
178   A         0.112   0.197   0.161  -0.029   0.076   0.053  -0.198  -0.095  -0.118
179   S        -0.873  -0.835  -0.840  -1.103  -1.074  -1.051  -0.833  -0.786  -0.754
180   P         0.565   0.409   0.328   0.802   0.601   0.480   0.565   0.326   0.179
181   H        -0.873  -0.855  -0.845  -0.694  -0.706  -0.690  -0.833  -0.807  -0.760
182   C        -0.873  -0.802  -0.837  -0.783  -0.694  -0.710  -0.833  -0.747  -0.751
183   T         0.253   0.157   0.190   0.172   0.063   0.065   0.057  -0.075  -0.058
184   M        -0.873  -0.892  -0.858  -0.984  -1.011  -0.910  -0.833  -0.832  -0.769
185   V         0.705   0.743   0.831   0.378   0.401   0.511   0.311   0.350   0.459
186   A        -0.340  -0.404  -0.371  -0.191  -0.273  -0.208  -0.452  -0.502  -0.465
187   T         0.112   0.072   0.158  -0.071  -0.115  -0.006  -0.198  -0.220  -0.114
188   Y         0.253   0.309   0.218   0.311   0.385   0.213   0.057   0.115  -0.018
189   H         1.959   2.041   2.143   2.191   2.315   2.486   2.218   2.351   2.538
190   K        -1.326  -1.298  -1.240  -1.121  -1.064  -0.962  -1.088  -1.039  -0.949
191   D        -0.076   0.148  -0.207   0.092   0.413  -0.108  -0.071   0.242  -0.241
192   I        -0.873  -0.753  -0.841  -0.776  -0.628  -0.708  -0.833  -0.715  -0.755
193   K        -0.669  -0.688  -0.777  -0.358  -0.405  -0.511  -0.579  -0.597  -0.675
194   D        -1.354  -1.354  -1.273  -1.414  -1.495  -1.329  -1.103  -1.084  -0.975
195   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
196   E        -1.354  -1.297  -1.255  -1.498  -1.469  -1.358  -1.103  -1.034  -0.960
197   N        -0.837  -0.743  -0.829  -0.617  -0.486  -0.610  -0.771  -0.652  -0.733
198   R        -0.461  -0.393  -0.429  -0.563  -0.470  -0.484  -0.605  -0.523  -0.543
199   T        -0.603  -0.543  -0.482  -0.957  -0.866  -0.774  -0.771  -0.695  -0.603
200   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
201   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
202   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
203   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
204   W        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
205   N        -0.873  -0.791  -0.830  -1.049  -0.955  -0.974  -0.833  -0.734  -0.743
206   N        -1.654  -1.606  -1.551  -1.416  -1.384  -1.271  -1.215  -1.156  -1.065
207   N         0.565   0.489   0.343   0.806   0.722   0.506   0.565   0.452   0.202
208   Y         1.959   2.041   2.143   2.089   2.221   2.382   2.218   2.351   2.538
209   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
210   P         1.959   2.041   2.143   2.039   2.161   2.330   2.218   2.351   2.538
211   D        -0.076   0.009  -0.232  -0.048   0.087  -0.263  -0.071   0.048  -0.275
212   K        -1.326  -1.365  -1.264  -1.318  -1.334  -1.204  -1.088  -1.095  -0.969
213   L         0.253   0.420   0.260  -0.056   0.194  -0.058   0.057   0.316   0.059
214   T        -0.873  -0.861  -0.836  -0.970  -0.939  -0.915  -0.833  -0.807  -0.748
215   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
219   L         1.245   1.135   1.124   1.088   0.944   0.941   1.328   1.126   1.068
220   L         1.959   2.041   2.143   1.715   1.827   1.999   2.218   2.351   2.538
221   Q        -0.873  -0.897  -0.857  -0.862  -0.893  -0.800  -0.833  -0.835  -0.769
222   F         0.112   0.111   0.158   0.125   0.150   0.232  -0.198  -0.179  -0.118
223   M        -0.421  -0.501  -0.408  -0.339  -0.431  -0.296  -0.579  -0.642  -0.521
224   A         1.245   1.135   1.124   1.341   1.185   1.159   1.328   1.126   1.068
225   T         0.253   0.429   0.272   0.130   0.425   0.163   0.057   0.334   0.082
226   T        -0.340  -0.468  -0.399  -0.388  -0.535  -0.471  -0.452  -0.587  -0.505
227   I        -0.076  -0.075  -0.255   0.032   0.031  -0.268  -0.071  -0.074  -0.305
228   V        -0.545  -0.499  -0.460  -0.732  -0.680  -0.630  -0.706  -0.650  -0.582
229   D        -0.873  -0.975  -0.873  -0.991  -1.157  -1.011  -0.833  -0.906  -0.784
230   I        -0.012   0.055   0.088  -0.274  -0.194  -0.185  -0.325  -0.232  -0.206
231   D        -1.654  -1.646  -1.570  -1.564  -1.554  -1.448  -1.215  -1.187  -1.079
232   V        -0.076  -0.178  -0.289   0.160   0.005  -0.174  -0.071  -0.210  -0.350
233   V        -0.837  -0.760  -0.810  -0.892  -0.775  -0.829  -0.771  -0.678  -0.712
234   L        -0.979  -0.948  -0.885  -1.128  -1.046  -1.004  -0.937  -0.892  -0.797
235   T        -1.326  -1.327  -1.248  -1.081  -1.036  -0.937  -1.088  -1.065  -0.956
236   G        -1.654  -1.656  -1.576  -1.550  -1.612  -1.453  -1.215  -1.194  -1.083
237   T        -0.669  -0.613  -0.748  -0.668  -0.582  -0.797  -0.579  -0.504  -0.644
238   L        -0.040  -0.047   0.073  -0.448  -0.452  -0.279  -0.386  -0.389  -0.234
239   D         1.105   1.030   1.000   1.195   1.102   1.060   1.088   0.931   0.818
240   T        -0.396  -0.402  -0.430  -0.480  -0.488  -0.563  -0.494  -0.499  -0.533
241   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
242   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
243   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
244   E         0.253   0.216   0.224   0.141   0.109   0.096   0.057   0.025   0.002
245   E        -0.340  -0.305  -0.353  -0.424  -0.367  -0.442  -0.452  -0.399  -0.449
246   V        -0.340  -0.369  -0.396  -0.458  -0.485  -0.483  -0.452  -0.503  -0.505
247   S        -0.340  -0.307  -0.365  -0.371  -0.312  -0.412  -0.452  -0.400  -0.463
248   E        -0.340  -0.178  -0.330  -0.283  -0.047  -0.268  -0.452  -0.242  -0.418
249   L        -0.873  -0.802  -0.837  -0.799  -0.679  -0.756  -0.833  -0.747  -0.751
250   L        -0.545  -0.499  -0.470  -0.744  -0.629  -0.582  -0.706  -0.655  -0.592
251   N        -0.340  -0.275  -0.374  -0.409  -0.331  -0.430  -0.452  -0.402  -0.477
252   E        -0.997  -0.928  -0.894  -1.069  -1.004  -0.932  -0.960  -0.871  -0.808
253   F         0.253   0.324   0.239   0.070   0.189   0.092   0.057   0.184   0.024
254   R        -1.202  -1.194  -1.191  -0.869  -0.871  -0.877  -0.960  -0.940  -0.903
255   I        -0.340  -0.426  -0.380  -0.338  -0.444  -0.402  -0.452  -0.528  -0.476
256   P         1.959   2.041   2.143   2.039   2.161   2.330   2.218   2.351   2.538
257   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
258   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
259   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
260   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
261   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
262   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
263   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
264   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
265   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
266   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
267   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
268   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
269   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
270   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
271   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
272   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
273   R        -1.654  -1.655  -1.571  -1.230  -1.228  -1.109  -1.215  -1.193  -1.080
274   G        -0.012   0.040   0.083  -0.097  -0.037  -0.007  -0.325  -0.253  -0.214
275   L        -0.076  -0.284  -0.323  -0.049  -0.315  -0.328  -0.071  -0.340  -0.396
276   N         0.565   0.381   0.318   0.839   0.622   0.529   0.565   0.284   0.163
277   N        -0.421  -0.518  -0.421  -0.589  -0.722  -0.582  -0.579  -0.659  -0.535
278   D        -0.873  -0.808  -0.820  -0.874  -0.785  -0.800  -0.833  -0.753  -0.734
279   I        -0.873  -0.975  -0.860  -0.843  -0.961  -0.805  -0.833  -0.907  -0.772
280   F        -0.340  -0.430  -0.376  -0.288  -0.430  -0.379  -0.452  -0.534  -0.474
281   Q        -0.873  -0.827  -0.857  -0.772  -0.729  -0.744  -0.833  -0.782  -0.771
282   L         0.112   0.193   0.172  -0.174  -0.076  -0.095  -0.198  -0.096  -0.104
283   R        -1.654  -1.653  -1.563  -1.484  -1.440  -1.348  -1.215  -1.192  -1.074
284   L         0.565   0.381   0.318   0.498   0.255   0.187   0.565   0.284   0.163
285   V        -0.340  -0.355  -0.398  -0.414  -0.485  -0.526  -0.452  -0.488  -0.507
286   N        -0.340  -0.474  -0.402  -0.161  -0.324  -0.226  -0.452  -0.595  -0.509
287   K         0.705   0.827   0.876   0.623   0.829   0.884   0.311   0.526   0.557
288   R         1.245   1.135   1.124   1.493   1.349   1.341   1.328   1.126   1.068
289   K         1.245   1.224   1.133   1.390   1.381   1.269   1.328   1.286   1.085
290   S         1.959   2.041   2.143   1.798   1.922   2.083   2.218   2.351   2.538
291   G         1.959   2.041   2.143   2.137   2.253   2.431   2.218   2.351   2.538
292   R         1.959   2.041   2.143   2.128   2.244   2.421   2.218   2.351   2.538
293   S        -0.340  -0.386  -0.383  -0.521  -0.593  -0.597  -0.452  -0.505  -0.488
294   L        -0.012  -0.050   0.048  -0.409  -0.475  -0.322  -0.325  -0.389  -0.266
295   E        -0.997  -0.959  -0.891  -1.098  -1.022  -0.940  -0.960  -0.905  -0.805
296   Y        -0.340  -0.373  -0.399  -0.260  -0.365  -0.386  -0.452  -0.507  -0.508
297   D        -1.326  -1.326  -1.250  -1.263  -1.283  -1.145  -1.088  -1.066  -0.958
298   F        -0.076  -0.167  -0.275   0.191   0.086  -0.106  -0.071  -0.192  -0.332
299   I        -1.202  -1.180  -1.186  -1.070  -1.045  -1.067  -0.960  -0.927  -0.898
300   V        -0.012  -0.002   0.070  -0.274  -0.328  -0.223  -0.325  -0.323  -0.233
301   N        -0.340  -0.474  -0.402  -0.313  -0.518  -0.450  -0.452  -0.595  -0.509
302   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
303   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
304   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
305   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
306   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
307   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
308   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
309   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
310   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
311   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
312   S        -0.076  -0.164  -0.279  -0.014  -0.124  -0.275  -0.071  -0.189  -0.337
313   N        -0.997  -0.944  -0.889  -1.217  -1.151  -1.077  -0.960  -0.893  -0.803
314   T        -0.340  -0.366  -0.395  -0.526  -0.652  -0.682  -0.452  -0.500  -0.503
315   H         0.565   0.381   0.318   0.878   0.602   0.465   0.565   0.284   0.163
316   E        -1.326  -1.310  -1.235  -1.286  -1.246  -1.140  -1.088  -1.054  -0.946
317   Y         0.565   0.489   0.343   0.863   0.787   0.571   0.565   0.452   0.202
318   E        -1.202  -1.253  -1.216  -1.092  -1.181  -1.114  -0.960  -0.996  -0.925
319   L        -1.326  -1.277  -1.235  -1.354  -1.291  -1.202  -1.088  -1.029  -0.947
320   L        -1.202  -1.046  -1.168  -0.953  -0.709  -0.918  -0.960  -0.783  -0.880
321   S        -1.654  -1.656  -1.576  -1.483  -1.506  -1.383  -1.215  -1.194  -1.083
322   T        -0.873  -0.844  -0.831  -0.911  -0.848  -0.839  -0.833  -0.778  -0.742
323   T        -0.012  -0.008   0.066  -0.170  -0.182  -0.093  -0.325  -0.325  -0.240
324   K        -0.012   0.005   0.072  -0.106  -0.103  -0.005  -0.325  -0.312  -0.231
325   Q        -0.545  -0.598  -0.469  -0.651  -0.699  -0.514  -0.706  -0.743  -0.591
326   E        -1.654  -1.662  -1.564  -1.508  -1.475  -1.366  -1.215  -1.198  -1.074
327   E        -1.326  -1.318  -1.240  -1.257  -1.237  -1.119  -1.088  -1.059  -0.950
328   E         0.450   0.493   0.336   0.475   0.543   0.311   0.391   0.454   0.192
329   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
330   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
331   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
332   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
333   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
334   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
335   E        -0.076  -0.284  -0.323   0.029  -0.266  -0.332  -0.071  -0.340  -0.396
336   T        -0.997  -0.986  -0.901  -1.187  -1.159  -1.059  -0.960  -0.925  -0.812
337   P        -0.873  -0.974  -0.879  -0.803  -0.934  -0.801  -0.833  -0.906  -0.790
338   E        -0.340  -0.404  -0.371  -0.497  -0.555  -0.542  -0.452  -0.502  -0.465
339   M         0.253   0.162   0.197   0.379   0.250   0.237   0.057  -0.065  -0.047
340   L        -0.076  -0.200  -0.292  -0.153  -0.347  -0.468  -0.071  -0.236  -0.354
341   Q        -0.545  -0.481  -0.462  -0.619  -0.541  -0.510  -0.706  -0.631  -0.582
342   G         0.056  -0.019   0.110   0.013  -0.094   0.106  -0.273  -0.352  -0.184
343   L         1.182   1.027   1.063   1.029   0.814   0.863   1.221   0.925   0.947
344   T         0.565   0.381   0.318   0.645   0.390   0.259   0.565   0.284   0.163
345   T         1.245   1.135   1.124   1.271   1.125   1.088   1.328   1.126   1.068
346   F         1.959   2.041   2.143   2.048   2.167   2.339   2.218   2.351   2.538
347   N         1.959   2.041   2.143   2.043   2.173   2.335   2.218   2.351   2.538
348   L         1.959   2.041   2.143   1.715   1.827   1.999   2.218   2.351   2.538
349   G        -0.545  -0.498  -0.463  -0.631  -0.557  -0.511  -0.706  -0.652  -0.585
350   T         0.565   0.381   0.318   0.631   0.370   0.232   0.565   0.284   0.163
351   S         1.245   1.224   1.133   1.154   1.143   1.004   1.328   1.286   1.085
352   N        -0.873  -0.740  -0.813  -1.024  -0.798  -0.914  -0.833  -0.667  -0.720
353   K         1.245   1.257   1.134   1.390   1.424   1.270   1.328   1.342   1.087
354   Q         0.565   0.409   0.328   0.809   0.595   0.454   0.565   0.326   0.179
355   K         0.253   0.153   0.160   0.330   0.168   0.195   0.057  -0.117  -0.108
356   L        -0.669  -0.801  -0.815  -0.698  -0.886  -0.889  -0.579  -0.721  -0.718
357   A         0.565   0.381   0.318   0.721   0.450   0.339   0.565   0.284   0.163
358   K         0.645   0.707   0.815   0.484   0.575   0.744   0.184   0.272   0.424
359   D         0.705   0.778   0.851   0.424   0.538   0.623   0.311   0.424   0.502
360   Q         0.253   0.138   0.158   0.366   0.174   0.201   0.057  -0.131  -0.112
361   V         1.245   1.224   1.133   1.379   1.363   1.233   1.328   1.286   1.085
362   A        -0.076  -0.178  -0.289   0.026  -0.125  -0.283  -0.071  -0.210  -0.350
363   L         1.959   2.041   2.143   1.715   1.827   1.999   2.218   2.351   2.538
364   P         1.959   2.041   2.143   2.039   2.161   2.330   2.218   2.351   2.538
365   F         0.705   0.716   0.817   0.597   0.593   0.744   0.311   0.291   0.428
366   L        -0.012   0.011   0.081  -0.272  -0.259  -0.126  -0.325  -0.305  -0.217
367   E        -0.076  -0.192  -0.286  -0.017  -0.213  -0.353  -0.071  -0.226  -0.346
368   A         1.245   1.257   1.134   1.341   1.365   1.176   1.328   1.342   1.087
369   Q         1.959   2.041   2.143   2.082   2.212   2.375   2.218   2.351   2.538
370   S        -0.873  -0.974  -0.879  -0.993  -1.078  -0.962  -0.833  -0.906  -0.790
371   F        -1.654  -1.650  -1.568  -1.601  -1.586  -1.515  -1.215  -1.190  -1.078
372   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
373   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
374   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
375   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
376   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
377   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
378   -        -0.566  -0.487  -0.454  -0.666  -0.568  -0.530  -0.711  -0.610  -0.563
379   -         1.011   0.970   1.001   1.168   1.093   1.136   0.916   0.814   0.820
380   G        -1.326  -1.184  -1.222  -1.177  -0.962  -1.036  -1.088  -0.947  -0.936
381   Q        -0.997  -1.043  -0.900  -1.108  -1.157  -0.966  -0.960  -0.973  -0.813
382   G         1.245   1.135   1.124   1.485   1.331   1.315   1.328   1.126   1.068
383   G         1.959   2.041   2.143   2.137   2.253   2.431   2.218   2.351   2.538
384   A         0.565   0.381   0.318   0.755   0.498   0.405   0.565   0.284   0.163
385   I         1.959   2.041   2.143   1.950   2.078   2.240   2.218   2.351   2.538
386   V         0.565   0.381   0.318   0.706   0.431   0.294   0.565   0.284   0.163
387   Y         1.959   2.041   2.143   2.089   2.221   2.382   2.218   2.351   2.538
388   E        -0.076  -0.284  -0.323   0.062  -0.212  -0.272  -0.071  -0.340  -0.396
389   Y        -0.421  -0.518  -0.412  -0.307  -0.414  -0.253  -0.579  -0.659  -0.526
390   E         0.565   0.381   0.318   0.640   0.390   0.302   0.565   0.284   0.163
391   K         0.565   0.381   0.318   0.748   0.489   0.390   0.565   0.284   0.163
392   D         0.565   0.381   0.318   0.697   0.438   0.320   0.565   0.284   0.163
393   D         1.959   2.041   2.143   1.976   2.098   2.266   2.218   2.351   2.538
394   D         1.959   2.041   2.143   1.976   2.098   2.266   2.218   2.351   2.538
395   Y         0.893   0.818   0.880   0.952   0.808   0.878   0.692   0.507   0.565
396   D         1.959   2.041   2.143   1.976   2.098   2.266   2.218   2.351   2.538
397   E         1.959   2.041   2.143   1.880   1.999   2.167   2.218   2.351   2.538
398   E         1.959   2.041   2.143   1.880   1.999   2.167   2.218   2.351   2.538
399   D         1.182   1.027   1.063   1.231   0.994   1.038   1.221   0.925   0.947
400   P         1.182   1.027   1.063   1.323   1.099   1.144   1.221   0.925   0.947
401   Y         1.182   1.027   1.063   1.358   1.145   1.189   1.221   0.925   0.947
402   E         1.245   1.135   1.124   1.242   1.100   1.084   1.328   1.126   1.068
403   D         1.245   1.135   1.124   1.325   1.177   1.154   1.328   1.126   1.068
404   P         0.565   0.381   0.318   0.755   0.493   0.372   0.565   0.284   0.163
405   F         0.565   0.381   0.318   0.734   0.448   0.322   0.565   0.284   0.163
406   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
407   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P38874
Output conservation file - output/P38874
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
