1     M         1.515   1.585   1.656   1.670   1.777   1.886   1.661   1.767   1.881
2     -        -0.806  -0.840  -0.701  -0.989  -1.078  -0.857  -0.928  -0.938  -0.762
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -0.144  -0.164  -0.131  -0.376  -0.428  -0.356  -0.346  -0.380  -0.344
7     N         1.515   1.585   1.656   1.462   1.569   1.681   1.661   1.767   1.881
8     I        -0.602  -0.543  -0.623  -0.808  -0.752  -0.821  -0.691  -0.631  -0.679
9     S         0.231   0.094  -0.028   0.358   0.159  -0.024   0.205  -0.006  -0.189
10    G         0.534   0.489   0.513   0.475   0.369   0.396   0.317   0.211   0.200
11    T         0.231   0.050  -0.037   0.380   0.093  -0.028   0.205  -0.063  -0.203
12    L        -0.359  -0.413  -0.557  -0.385  -0.438  -0.647  -0.355  -0.431  -0.589
13    N         0.858   0.681   0.679   0.884   0.648   0.637   0.877   0.571   0.525
14    T        -1.093  -1.158  -1.062  -1.113  -1.190  -1.036  -1.027  -1.062  -0.925
15    L        -1.207  -1.219  -1.083  -1.233  -1.184  -1.009  -1.139  -1.117  -0.944
16    R        -0.056  -0.210  -0.139   0.000  -0.210  -0.158  -0.243  -0.443  -0.364
17    L         0.231   0.094  -0.028   0.130  -0.053  -0.252   0.205  -0.006  -0.189
18    L        -0.676  -0.552  -0.627  -0.852  -0.691  -0.709  -0.803  -0.650  -0.686
19    Y        -0.905  -1.019  -1.025  -0.592  -0.743  -0.806  -0.803  -0.914  -0.886
20    N         0.231   0.300   0.007   0.286   0.394  -0.059   0.205   0.312  -0.135
21    P         0.858   0.946   0.703   0.983   1.102   0.795   0.877   1.015   0.572
22    S        -0.056  -0.058  -0.119  -0.064  -0.088  -0.177  -0.243  -0.267  -0.340
23    L         0.858   0.681   0.679   0.733   0.524   0.513   0.877   0.571   0.525
24    C         0.534   0.453   0.506   0.636   0.445   0.511   0.317   0.139   0.187
25    K        -0.374  -0.310  -0.217  -0.825  -0.721  -0.577  -0.691  -0.594  -0.471
26    P         1.515   1.585   1.656   1.541   1.638   1.759   1.661   1.767   1.881
27    S        -0.056   0.077  -0.081   0.077   0.291   0.036  -0.243  -0.033  -0.276
28    L        -0.791  -0.772  -0.687  -1.106  -1.066  -0.930  -0.915  -0.874  -0.750
29    V        -0.359  -0.185  -0.518  -0.197   0.050  -0.460  -0.355  -0.116  -0.540
30    V        -0.359  -0.449  -0.569  -0.273  -0.393  -0.553  -0.355  -0.472  -0.603
31    P        -0.791  -0.704  -0.668  -0.925  -0.768  -0.729  -0.915  -0.785  -0.727
32    T        -0.300  -0.184  -0.172  -0.452  -0.270  -0.276  -0.579  -0.403  -0.405
33    F         1.515   1.585   1.656   1.619   1.728   1.835   1.661   1.767   1.881
34    N        -0.300  -0.278  -0.196  -0.511  -0.493  -0.370  -0.579  -0.552  -0.442
35    D        -0.602  -0.446  -0.594  -0.484  -0.240  -0.481  -0.691  -0.485  -0.641
36    L         0.534   0.473   0.505   0.240   0.117   0.158   0.317   0.179   0.184
37    P         0.231   0.388   0.020   0.394   0.606   0.090   0.205   0.438  -0.117
38    I        -0.602  -0.690  -0.632  -0.704  -0.810  -0.748  -0.691  -0.767  -0.684
39    P         0.858   0.681   0.679   0.955   0.705   0.694   0.877   0.571   0.525
40    I        -0.300  -0.187  -0.175  -0.531  -0.378  -0.371  -0.579  -0.408  -0.410
41    H        -1.510  -1.362  -1.378  -1.406  -1.210  -1.207  -1.251  -1.100  -1.052
42    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
45    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
46    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
47    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
48    -        -0.144  -0.161  -0.140  -0.151  -0.196  -0.166  -0.346  -0.379  -0.357
49    -        -1.294  -1.245  -1.112  -1.233  -1.151  -0.966  -1.206  -1.133  -0.968
50    -        -1.294  -1.245  -1.112  -1.494  -1.413  -1.222  -1.206  -1.133  -0.968
51    -        -0.810  -0.806  -0.698  -0.952  -0.946  -0.807  -0.920  -0.900  -0.756
52    D        -0.905  -0.767  -0.965  -0.847  -0.641  -0.942  -0.803  -0.624  -0.825
53    S        -1.207  -1.097  -1.071  -1.080  -0.951  -0.884  -1.139  -1.016  -0.935
54    I         1.515   1.585   1.656   1.472   1.540   1.691   1.661   1.767   1.881
55    K         0.858   0.681   0.679   0.825   0.611   0.600   0.877   0.571   0.525
56    A        -0.056   0.095  -0.069  -0.086   0.142  -0.119  -0.243  -0.003  -0.256
57    V         0.231   0.105  -0.024   0.202  -0.006  -0.210   0.205   0.009  -0.183
58    V         0.858   0.904   0.703   0.810   0.884   0.598   0.877   0.948   0.571
59    L         0.231   0.389   0.020   0.118   0.346  -0.196   0.205   0.438  -0.117
60    D         1.515   1.585   1.656   1.479   1.584   1.698   1.661   1.767   1.881
61    K         1.515   1.585   1.656   1.389   1.500   1.609   1.661   1.767   1.881
62    D         1.515   1.585   1.656   1.479   1.584   1.698   1.661   1.767   1.881
63    N         0.858   0.896   0.702   0.878   0.946   0.663   0.877   0.936   0.569
64    C         1.515   1.585   1.656   1.705   1.807   1.920   1.661   1.767   1.881
65    I        -0.056  -0.068  -0.129   0.038  -0.028  -0.091  -0.243  -0.280  -0.352
66    A         0.858   0.681   0.679   0.943   0.692   0.696   0.877   0.571   0.525
67    F        -1.093  -1.064  -1.051  -1.244  -1.214  -1.164  -1.027  -0.982  -0.917
68    P        -0.186  -0.095  -0.128  -0.290  -0.148  -0.162  -0.467  -0.327  -0.354
69    H        -0.602  -0.723  -0.648  -0.479  -0.680  -0.587  -0.691  -0.811  -0.706
70    D        -0.359  -0.529  -0.588  -0.189  -0.425  -0.508  -0.355  -0.566  -0.627
71    D         0.231   0.050  -0.037   0.324   0.070  -0.075   0.205  -0.063  -0.203
72    K        -0.359  -0.529  -0.588  -0.273  -0.506  -0.576  -0.355  -0.566  -0.627
73    I         0.534   0.489   0.513   0.337   0.235   0.258   0.317   0.211   0.200
74    W        -0.359  -0.529  -0.588   0.041  -0.208  -0.307  -0.355  -0.566  -0.627
75    P        -0.186  -0.140  -0.149  -0.236  -0.175  -0.145  -0.467  -0.409  -0.387
76    D        -0.676  -0.589  -0.627  -0.668  -0.545  -0.567  -0.803  -0.687  -0.686
77    Y         0.858   0.681   0.679   1.066   0.851   0.817   0.877   0.571   0.525
78    L        -1.813  -1.712  -1.656  -1.721  -1.582  -1.474  -1.363  -1.251  -1.148
79    Q        -1.093  -1.136  -1.044  -0.977  -1.058  -0.921  -1.027  -1.039  -0.908
80    H        -1.093  -0.952  -1.015  -1.032  -0.829  -0.873  -1.027  -0.848  -0.879
81    W        -0.056  -0.210  -0.139   0.159  -0.081   0.007  -0.243  -0.443  -0.364
82    E        -0.791  -0.833  -0.685  -0.899  -0.903  -0.726  -0.915  -0.926  -0.746
83    T        -1.093  -0.938  -1.015  -1.038  -0.775  -0.903  -1.027  -0.839  -0.880
84    L         0.858   0.681   0.679   0.733   0.524   0.514   0.877   0.571   0.525
85    R        -0.602  -0.641  -0.632  -0.616  -0.646  -0.619  -0.691  -0.723  -0.686
86    S        -1.813  -1.795  -1.671  -1.553  -1.556  -1.373  -1.363  -1.320  -1.159
87    K        -1.510  -1.424  -1.373  -1.559  -1.438  -1.371  -1.251  -1.150  -1.049
88    Y         1.515   1.585   1.656   1.638   1.758   1.854   1.661   1.767   1.881
89    S        -0.359  -0.414  -0.569  -0.139  -0.246  -0.446  -0.355  -0.432  -0.603
90    N        -1.396  -1.333  -1.353  -1.257  -1.163  -1.228  -1.139  -1.067  -1.029
91    K        -0.499  -0.342  -0.571  -0.471  -0.232  -0.571  -0.533  -0.318  -0.606
92    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
93    A        -1.510  -1.502  -1.395  -1.275  -1.275  -1.126  -1.251  -1.215  -1.064
94    L         0.534   0.468   0.507   0.214   0.091   0.117   0.317   0.169   0.188
95    L         0.858   0.681   0.679   0.711   0.474   0.463   0.877   0.571   0.525
96    I         0.231   0.057  -0.033   0.267  -0.043  -0.181   0.205  -0.054  -0.196
97    V         0.858   0.681   0.679   0.785   0.533   0.500   0.877   0.571   0.525
98    S         1.515   1.585   1.656   1.509   1.601   1.727   1.661   1.767   1.881
99    N         1.515   1.585   1.656   1.462   1.569   1.681   1.661   1.767   1.881
100   T         0.534   0.623   0.553   0.468   0.592   0.466   0.317   0.465   0.280
101   A         0.858   0.681   0.679   0.933   0.669   0.675   0.877   0.571   0.525
102   G         1.515   1.585   1.656   1.531   1.624   1.749   1.661   1.767   1.881
103   S        -0.056   0.027  -0.096  -0.053   0.074  -0.122  -0.243  -0.101  -0.298
104   N        -0.905  -0.971  -1.004  -0.816  -0.907  -1.000  -0.803  -0.867  -0.865
105   S        -0.056  -0.171  -0.129  -0.133  -0.310  -0.276  -0.243  -0.382  -0.349
106   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
107   D         1.515   1.585   1.656   1.479   1.584   1.698   1.661   1.767   1.881
108   K        -0.791  -0.835  -0.687  -0.982  -1.043  -0.807  -0.915  -0.929  -0.748
109   D        -0.791  -0.824  -0.681  -0.921  -0.953  -0.743  -0.915  -0.916  -0.741
110   Y        -0.791  -0.772  -0.687  -0.685  -0.669  -0.530  -0.915  -0.874  -0.750
111   S        -2.115  -2.058  -1.920  -2.020  -1.890  -1.739  -1.475  -1.403  -1.235
112   Q        -0.359  -0.529  -0.588  -0.083  -0.370  -0.473  -0.355  -0.566  -0.627
113   A         1.515   1.585   1.656   1.518   1.609   1.736   1.661   1.767   1.881
114   K        -0.602  -0.707  -0.641  -0.670  -0.815  -0.696  -0.691  -0.790  -0.697
115   L        -1.396  -1.408  -1.371  -1.229  -1.220  -1.226  -1.139  -1.132  -1.044
116   L        -0.056  -0.210  -0.139  -0.308  -0.500  -0.425  -0.243  -0.443  -0.364
117   E         0.858   0.681   0.679   1.003   0.793   0.774   0.877   0.571   0.525
118   D        -0.602  -0.531  -0.624  -0.647  -0.554  -0.657  -0.691  -0.629  -0.680
119   K        -1.093  -1.033  -1.036  -1.172  -1.105  -1.088  -1.027  -0.955  -0.903
120   T         0.858   0.681   0.679   0.987   0.763   0.772   0.877   0.571   0.525
121   G         0.858   0.681   0.679   0.945   0.691   0.684   0.877   0.571   0.525
122   I        -0.186  -0.124  -0.132  -0.472  -0.381  -0.392  -0.467  -0.359  -0.362
123   P        -0.602  -0.498  -0.608  -0.550  -0.394  -0.561  -0.691  -0.544  -0.659
124   V         1.515   1.585   1.656   1.395   1.504   1.616   1.661   1.767   1.881
125   L         0.231   0.057  -0.033   0.148  -0.092  -0.222   0.205  -0.054  -0.196
126   R        -0.359  -0.239  -0.524  -0.092   0.090  -0.354  -0.355  -0.186  -0.548
127   H         1.515   1.585   1.656   1.657   1.763   1.873   1.661   1.767   1.881
128   S        -0.905  -0.814  -0.974  -0.753  -0.627  -0.883  -0.803  -0.678  -0.834
129   T        -1.207  -1.223  -1.080  -1.417  -1.474  -1.246  -1.139  -1.120  -0.942
130   K         0.858   0.681   0.679   0.778   0.529   0.493   0.877   0.571   0.525
131   K         1.515   1.585   1.656   1.389   1.500   1.609   1.661   1.767   1.881
132   P         1.515   1.585   1.656   1.541   1.638   1.759   1.661   1.767   1.881
133   G         0.858   0.681   0.679   0.922   0.652   0.631   0.877   0.571   0.525
134   C         1.515   1.585   1.656   1.705   1.807   1.920   1.661   1.767   1.881
135   H        -0.905  -0.971  -1.004  -0.610  -0.723  -0.810  -0.803  -0.867  -0.865
136   N        -0.791  -0.687  -0.668  -0.919  -0.723  -0.741  -0.915  -0.775  -0.728
137   E         0.858   0.904   0.703   0.980   1.068   0.761   0.877   0.948   0.571
138   I         0.534   0.453   0.506   0.355   0.139   0.216   0.317   0.139   0.187
139   L        -1.813  -1.759  -1.663  -1.568  -1.457  -1.377  -1.363  -1.295  -1.153
140   D        -1.510  -1.513  -1.394  -1.376  -1.388  -1.187  -1.251  -1.223  -1.064
141   Y         1.515   1.585   1.656   1.638   1.758   1.854   1.661   1.767   1.881
142   F         0.534   0.453   0.506   0.499   0.316   0.345   0.317   0.139   0.187
143   Y        -0.905  -0.932  -1.001  -0.795  -0.848  -0.911  -0.803  -0.828  -0.861
144   R        -0.905  -0.962  -1.021  -0.825  -0.924  -0.985  -0.803  -0.858  -0.882
145   N        -1.396  -1.243  -1.337  -1.223  -0.981  -1.136  -1.139  -0.963  -1.015
146   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
147   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
148   K        -0.654  -0.697  -0.655  -0.737  -0.815  -0.745  -0.729  -0.771  -0.707
149   T        -1.510  -1.480  -1.389  -1.522  -1.442  -1.339  -1.251  -1.201  -1.060
150   I        -0.186  -0.134  -0.139  -0.385  -0.363  -0.282  -0.467  -0.405  -0.376
151   T        -0.714  -0.768  -0.666  -0.725  -0.815  -0.660  -0.826  -0.862  -0.725
152   N        -1.510  -1.387  -1.379  -1.477  -1.274  -1.263  -1.251  -1.117  -1.053
153   P         0.534   0.489   0.511   0.493   0.390   0.405   0.317   0.211   0.196
154   K        -1.093  -0.961  -1.024  -1.084  -0.859  -0.971  -1.027  -0.857  -0.888
155   E         0.534   0.450   0.502   0.556   0.418   0.476   0.317   0.133   0.179
156   V         0.360   0.443   0.492   0.052   0.163   0.238  -0.019   0.120   0.157
157   A        -0.359  -0.377  -0.554  -0.263  -0.352  -0.622  -0.355  -0.390  -0.585
158   V         0.858   0.681   0.679   0.832   0.615   0.607   0.877   0.571   0.525
159   V         0.305   0.356   0.464  -0.077  -0.025   0.171  -0.131  -0.057   0.101
160   G         1.515   1.585   1.656   1.531   1.624   1.749   1.661   1.767   1.881
161   D         1.515   1.585   1.656   1.479   1.584   1.698   1.661   1.767   1.881
162   R         1.515   1.585   1.656   1.616   1.729   1.832   1.661   1.767   1.881
163   L         1.515   1.585   1.656   1.296   1.411   1.518   1.661   1.767   1.881
164   F        -0.056  -0.133  -0.141  -0.053  -0.237  -0.263  -0.243  -0.373  -0.370
165   T         1.515   1.585   1.656   1.538   1.630   1.756   1.661   1.767   1.881
166   D         1.515   1.585   1.656   1.479   1.584   1.698   1.661   1.767   1.881
167   I        -0.374  -0.323  -0.219  -0.559  -0.514  -0.340  -0.691  -0.611  -0.473
168   L        -0.602  -0.722  -0.650  -0.798  -0.944  -0.824  -0.691  -0.808  -0.707
169   M         0.534   0.450   0.502   0.549   0.355   0.380   0.317   0.133   0.179
170   A         1.515   1.585   1.656   1.518   1.609   1.736   1.661   1.767   1.881
171   N         1.515   1.585   1.656   1.462   1.569   1.681   1.661   1.767   1.881
172   L        -0.905  -0.948  -1.011  -0.604  -0.703  -0.823  -0.803  -0.844  -0.872
173   M         0.858   0.904   0.703   1.085   1.158   0.860   0.877   0.948   0.571
174   G         1.515   1.585   1.656   1.531   1.624   1.749   1.661   1.767   1.881
175   S         0.231   0.307   0.001   0.362   0.461   0.033   0.205   0.322  -0.144
176   Y        -0.186  -0.167  -0.145  -0.095  -0.051  -0.016  -0.467  -0.437  -0.381
177   G         0.858   0.959   0.708   0.952   1.082   0.748   0.877   1.035   0.581
178   V        -0.056   0.081  -0.094  -0.165   0.023  -0.200  -0.243  -0.041  -0.298
179   W         1.515   1.585   1.656   1.711   1.823   1.926   1.661   1.767   1.881
180   I         0.305   0.361   0.467  -0.150  -0.092   0.096  -0.131  -0.045   0.106
181   R        -1.813  -1.778  -1.669  -1.591  -1.550  -1.384  -1.363  -1.308  -1.158
182   D        -0.676  -0.717  -0.648  -0.663  -0.694  -0.573  -0.803  -0.826  -0.708
183   G         1.515   1.585   1.656   1.531   1.624   1.749   1.661   1.767   1.881
184   V         1.515   1.585   1.656   1.395   1.504   1.616   1.661   1.767   1.881
185   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
186   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
187   K        -1.093  -1.144  -1.058  -1.041  -1.099  -0.979  -1.027  -1.047  -0.921
188   V        -1.510  -1.509  -1.400  -1.693  -1.656  -1.498  -1.251  -1.220  -1.068
189   S         0.231   0.050  -0.037   0.384   0.120   0.015   0.205  -0.063  -0.203
190   A        -1.813  -1.757  -1.663  -1.684  -1.613  -1.467  -1.363  -1.294  -1.153
191   N        -0.374  -0.327  -0.220  -0.710  -0.628  -0.468  -0.691  -0.617  -0.475
192   P        -1.510  -1.508  -1.390  -1.488  -1.468  -1.319  -1.251  -1.220  -1.061
193   L        -1.093  -1.162  -1.050  -1.046  -1.134  -0.980  -1.027  -1.061  -0.914
194   S        -0.791  -0.833  -0.685  -0.907  -0.943  -0.735  -0.915  -0.926  -0.746
195   K        -0.676  -0.733  -0.647  -0.798  -0.850  -0.750  -0.803  -0.837  -0.707
196   F        -0.676  -0.767  -0.651  -0.805  -0.879  -0.734  -0.803  -0.868  -0.711
197   E         1.515   1.585   1.656   1.566   1.669   1.783   1.661   1.767   1.881
198   K        -0.153  -0.094  -0.144  -0.157  -0.059  -0.152  -0.387  -0.292  -0.368
199   K        -1.536  -1.528  -1.404  -1.570  -1.554  -1.390  -1.265  -1.227  -1.071
200   L         0.471   0.484   0.500   0.090   0.088   0.087   0.198   0.201   0.173
201   Y         0.799   0.774   0.642   0.982   0.957   0.735   0.784   0.733   0.455
202   N        -0.499  -0.488  -0.613  -0.378  -0.356  -0.539  -0.533  -0.505  -0.657
203   F        -0.238  -0.189  -0.172  -0.191  -0.114  -0.058  -0.533  -0.458  -0.414
204   L         0.125   0.096  -0.073   0.073   0.048  -0.155   0.052   0.015  -0.257
205   G        -0.654  -0.589  -0.656  -0.658  -0.562  -0.650  -0.729  -0.630  -0.708
206   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
207   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
208   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
209   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
210   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
211   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
212   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
213   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
214   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
215   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
219   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
222   F        -1.536  -1.527  -1.405  -1.371  -1.333  -1.169  -1.265  -1.226  -1.071
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P38812
Output conservation file - output/P38812
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
