1     M         2.025   2.066   2.144   2.315   2.372   2.506   2.279   2.348   2.482
2     A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    S        -0.113  -0.068  -0.084  -0.100  -0.035  -0.038  -0.333  -0.266  -0.300
22    V        -0.714  -0.710  -0.677  -0.764  -0.757  -0.713  -0.730  -0.719  -0.671
23    D        -0.714  -0.713  -0.699  -0.985  -0.989  -1.008  -0.730  -0.723  -0.695
24    A        -1.284  -1.287  -1.204  -0.957  -0.953  -0.830  -1.065  -1.060  -0.955
25    A        -0.714  -0.704  -0.702  -0.771  -0.758  -0.743  -0.730  -0.713  -0.700
26    D        -0.714  -0.707  -0.690  -0.764  -0.754  -0.737  -0.730  -0.716  -0.686
27    G        -0.714  -0.713  -0.699  -0.565  -0.558  -0.533  -0.730  -0.723  -0.695
28    S        -0.714  -0.704  -0.702  -0.773  -0.758  -0.744  -0.730  -0.713  -0.700
29    V         0.641   0.662   0.725   0.448   0.472   0.560   0.273   0.298   0.381
30    S        -0.529  -0.585  -0.603  -0.584  -0.667  -0.696  -0.508  -0.575  -0.583
31    K        -1.184  -1.121  -1.140  -0.914  -0.821  -0.847  -0.972  -0.901  -0.896
32    I         0.600   0.626   0.704   0.085   0.133   0.236   0.189   0.226   0.337
33    E        -0.529  -0.445  -0.564  -0.245  -0.096  -0.335  -0.508  -0.396  -0.535
34    P         2.025   2.066   2.144   2.052   2.110   2.238   2.279   2.348   2.482
35    I        -0.709  -0.670  -0.668  -0.869  -0.789  -0.811  -0.740  -0.693  -0.667
36    A         0.716   0.770   0.767   0.646   0.724   0.715   0.421   0.512   0.466
37    D        -1.184  -1.200  -1.171  -0.942  -0.986  -0.946  -0.972  -0.983  -0.926
38    F         1.099   0.976   0.960   1.389   1.229   1.210   1.118   0.900   0.843
39    V         1.099   0.976   0.960   1.251   1.076   1.065   1.118   0.900   0.843
40    I         1.099   1.171   0.996   1.014   1.128   0.868   1.118   1.238   0.910
41    K         2.025   2.066   2.144   1.902   1.958   2.085   2.279   2.348   2.482
42    T         0.716   0.772   0.783   0.657   0.743   0.739   0.421   0.517   0.499
43    K         1.099   0.976   0.960   1.072   0.906   0.892   1.118   0.900   0.843
44    L        -0.054  -0.040  -0.046  -0.403  -0.394  -0.400  -0.275  -0.268  -0.260
45    L        -0.709  -0.741  -0.670  -0.857  -0.881  -0.793  -0.740  -0.768  -0.670
46    S        -0.709  -0.743  -0.683  -0.766  -0.804  -0.727  -0.740  -0.770  -0.683
47    A        -0.709  -0.667  -0.668  -0.753  -0.704  -0.705  -0.740  -0.690  -0.667
48    N        -0.113  -0.114  -0.077  -0.271  -0.284  -0.251  -0.333  -0.335  -0.290
49    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
50    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    G        -0.144  -0.134  -0.100  -0.222  -0.212  -0.166  -0.396  -0.382  -0.328
54    P        -0.714  -0.706  -0.682  -0.696  -0.680  -0.652  -0.730  -0.720  -0.677
55    E        -0.529  -0.574  -0.599  -0.648  -0.743  -0.777  -0.508  -0.562  -0.578
56    K        -0.709  -0.742  -0.677  -0.787  -0.824  -0.707  -0.740  -0.769  -0.676
57    L        -0.529  -0.568  -0.621  -0.492  -0.579  -0.603  -0.508  -0.556  -0.605
58    Q        -1.184  -1.115  -1.133  -0.921  -0.801  -0.848  -0.972  -0.894  -0.890
59    D        -1.184  -1.200  -1.171  -1.150  -1.149  -1.106  -0.972  -0.983  -0.926
60    G         0.071   0.133   0.043   0.258   0.351   0.193  -0.062   0.031  -0.111
61    R        -0.529  -0.455  -0.588  -0.239  -0.133  -0.327  -0.508  -0.408  -0.564
62    K         2.025   2.066   2.144   1.902   1.958   2.085   2.279   2.348   2.482
63    V         0.716   0.772   0.783   0.520   0.614   0.596   0.421   0.517   0.499
64    F         2.025   2.066   2.144   2.216   2.280   2.405   2.279   2.348   2.482
65    I         0.241   0.153   0.084   0.133  -0.008  -0.132   0.189   0.055  -0.050
66    N         2.025   2.066   2.144   2.112   2.180   2.300   2.279   2.348   2.482
67    V         0.241   0.320   0.115   0.292   0.412   0.053   0.189   0.308  -0.003
68    C         2.025   2.066   2.144   2.289   2.355   2.480   2.279   2.348   2.482
69    H         1.099   0.976   0.960   1.517   1.355   1.335   1.118   0.900   0.843
70    S        -0.054   0.008  -0.017  -0.221  -0.129  -0.160  -0.275  -0.187  -0.215
71    P        -0.529  -0.564  -0.594  -0.431  -0.511  -0.541  -0.508  -0.551  -0.572
72    L        -0.529  -0.578  -0.598  -0.307  -0.387  -0.454  -0.508  -0.567  -0.577
73    V         0.241   0.320   0.115   0.374   0.487   0.171   0.189   0.308  -0.003
74    P         2.025   2.066   2.144   2.052   2.110   2.238   2.279   2.348   2.482
75    K         0.241   0.167   0.088   0.132   0.004  -0.141   0.189   0.075  -0.044
76    P         2.025   2.066   2.144   2.052   2.110   2.238   2.279   2.348   2.482
77    E        -0.054  -0.041  -0.058  -0.235  -0.236  -0.228  -0.275  -0.268  -0.275
78    V        -0.709  -0.742  -0.683  -0.746  -0.782  -0.672  -0.740  -0.769  -0.683
79    D         0.716   0.687   0.734   0.530   0.455   0.522   0.421   0.349   0.399
80    F         2.025   2.066   2.144   2.216   2.280   2.405   2.279   2.348   2.482
81    N        -0.709  -0.748  -0.689  -0.748  -0.781  -0.697  -0.740  -0.774  -0.688
82    A         1.099   1.153   0.994   1.216   1.291   1.083   1.118   1.208   0.907
83    R        -1.184  -1.121  -1.140  -1.073  -0.985  -0.994  -0.972  -0.901  -0.896
84    I         0.241   0.164   0.082   0.208   0.107  -0.021   0.189   0.070  -0.053
85    V         0.241   0.164   0.082   0.292   0.149  -0.011   0.189   0.070  -0.053
86    F        -0.054  -0.121  -0.054   0.151   0.070   0.172  -0.275  -0.353  -0.265
87    P         1.099   0.976   0.960   1.193   1.018   0.992   1.118   0.900   0.843
88    L         2.025   2.066   2.144   1.889   1.952   2.072   2.279   2.348   2.482
89    I         1.099   0.976   0.960   0.983   0.810   0.758   1.118   0.900   0.843
90    I         1.099   0.976   0.960   1.049   0.900   0.870   1.118   0.900   0.843
91    Q        -0.709  -0.748  -0.694  -0.616  -0.656  -0.557  -0.740  -0.774  -0.694
92    N         1.099   0.976   0.960   1.207   1.024   0.972   1.118   0.900   0.843
93    E        -0.709  -0.748  -0.673  -0.769  -0.839  -0.724  -0.740  -0.774  -0.673
94    W         2.025   2.066   2.144   2.367   2.432   2.559   2.279   2.348   2.482
95    E         1.099   0.976   0.960   1.130   0.977   0.964   1.118   0.900   0.843
96    I         1.099   0.976   0.960   1.062   0.916   0.892   1.118   0.900   0.843
97    P         2.025   2.066   2.144   2.052   2.110   2.238   2.279   2.348   2.482
98    I         0.241   0.164   0.082   0.133   0.026  -0.135   0.189   0.070  -0.053
99    I         0.600   0.626   0.704   0.237   0.284   0.397   0.189   0.226   0.337
100   T        -0.709  -0.669  -0.670  -0.715  -0.684  -0.650  -0.740  -0.692  -0.669
101   S         1.099   0.976   0.960   1.155   0.985   0.974   1.118   0.900   0.843
102   C        -0.709  -0.669  -0.674  -0.765  -0.728  -0.681  -0.740  -0.692  -0.673
103   Y        -0.054  -0.003  -0.037  -0.295  -0.202  -0.245  -0.275  -0.199  -0.240
104   R         0.716   0.775   0.789   0.680   0.787   0.770   0.421   0.523   0.510
105   M        -1.184  -1.121  -1.140  -1.039  -0.965  -0.953  -0.972  -0.901  -0.896
106   D         0.241   0.326   0.116   0.316   0.434   0.122   0.189   0.318  -0.002
107   H        -0.709  -0.666  -0.672  -0.663  -0.598  -0.566  -0.740  -0.689  -0.670
108   D         2.025   2.066   2.144   2.013   2.068   2.198   2.279   2.348   2.482
109   K         1.099   0.976   0.960   1.044   0.868   0.844   1.118   0.900   0.843
110   K         2.025   2.066   2.144   1.902   1.958   2.085   2.279   2.348   2.482
111   G         1.099   0.976   0.960   1.350   1.152   1.118   1.118   0.900   0.843
112   Q         0.241   0.330   0.140   0.586   0.720   0.441   0.189   0.323   0.035
113   E        -0.709  -0.748  -0.694  -0.840  -0.926  -0.844  -0.740  -0.774  -0.694
114   C         0.716   0.775   0.789   0.754   0.860   0.848   0.421   0.523   0.510
115   Y         0.716   0.775   0.789   0.852   0.953   0.957   0.421   0.523   0.510
116   V         2.025   2.066   2.144   2.088   2.141   2.275   2.279   2.348   2.482
117   W        -0.709  -0.666  -0.671  -0.476  -0.389  -0.431  -0.740  -0.688  -0.669
118   D         2.025   2.066   2.144   2.013   2.068   2.198   2.279   2.348   2.482
119   C         2.025   2.066   2.144   2.289   2.355   2.480   2.279   2.348   2.482
120   C         1.099   0.976   0.960   1.422   1.245   1.215   1.118   0.900   0.843
121   I         0.716   0.687   0.734   0.421   0.367   0.427   0.421   0.349   0.399
122   N         0.241   0.153   0.084   0.423   0.279   0.179   0.189   0.055  -0.050
123   S        -0.054  -0.118  -0.044  -0.193  -0.311  -0.186  -0.275  -0.348  -0.254
124   D        -1.184  -1.189  -1.160  -1.376  -1.393  -1.378  -0.972  -0.973  -0.916
125   C         1.099   0.976   0.960   1.422   1.245   1.215   1.118   0.900   0.843
126   S        -0.709  -0.748  -0.694  -0.707  -0.796  -0.711  -0.740  -0.774  -0.694
127   R        -1.184  -1.200  -1.171  -1.019  -1.070  -1.036  -0.972  -0.983  -0.926
128   W         1.099   0.976   0.960   1.525   1.356   1.334   1.118   0.900   0.843
129   I        -0.709  -0.748  -0.689  -0.687  -0.748  -0.657  -0.740  -0.774  -0.688
130   C        -0.529  -0.585  -0.603  -0.110  -0.187  -0.208  -0.508  -0.575  -0.583
131   D        -1.184  -1.200  -1.171  -1.241  -1.271  -1.208  -0.972  -0.983  -0.926
132   D        -0.054  -0.041  -0.058  -0.221  -0.227  -0.234  -0.275  -0.268  -0.275
133   I        -1.184  -1.115  -1.133  -1.162  -1.052  -1.076  -0.972  -0.894  -0.890
134   Q        -0.054  -0.120  -0.059  -0.048  -0.157  -0.079  -0.275  -0.350  -0.271
135   L         1.099   0.976   0.960   1.026   0.851   0.823   1.118   0.900   0.843
136   R         0.600   0.626   0.703   0.376   0.395   0.522   0.189   0.227   0.336
137   E         0.600   0.625   0.704   0.205   0.239   0.360   0.189   0.225   0.338
138   I         1.099   0.976   0.960   0.973   0.796   0.740   1.118   0.900   0.843
139   L         0.716   0.772   0.783   0.433   0.518   0.522   0.421   0.517   0.499
140   V         0.600   0.625   0.704   0.237   0.267   0.384   0.189   0.225   0.338
141   E         2.025   2.066   2.144   1.939   2.001   2.123   2.279   2.348   2.482
142   W         1.099   0.976   0.960   1.517   1.345   1.321   1.118   0.900   0.843
143   C         2.025   2.066   2.144   2.289   2.355   2.480   2.279   2.348   2.482
144   L        -0.054  -0.120  -0.059  -0.329  -0.382  -0.306  -0.275  -0.350  -0.271
145   E         1.099   0.976   0.960   1.109   0.947   0.929   1.118   0.900   0.843
146   S         0.241   0.153   0.084   0.276   0.117   0.026   0.189   0.055  -0.050
147   C        -0.709  -0.669  -0.670  -0.580  -0.529  -0.528  -0.740  -0.692  -0.669
148   E         2.025   2.066   2.144   1.939   2.001   2.123   2.279   2.348   2.482
149   I         0.241   0.152   0.082   0.202   0.092  -0.036   0.189   0.054  -0.052
150   R        -0.529  -0.568  -0.621  -0.290  -0.354  -0.474  -0.508  -0.556  -0.605
151   D        -1.184  -1.121  -1.140  -0.874  -0.761  -0.813  -0.972  -0.901  -0.896
152   S        -1.184  -1.194  -1.153  -1.150  -1.150  -1.103  -0.972  -0.977  -0.909
153   V        -0.054  -0.004  -0.025  -0.336  -0.257  -0.302  -0.275  -0.201  -0.226
154   V        -0.709  -0.663  -0.669  -0.837  -0.761  -0.767  -0.740  -0.686  -0.668
155   L         0.716   0.772   0.783   0.332   0.434   0.409   0.421   0.517   0.499
156   C        -0.054  -0.001  -0.032  -0.219  -0.134  -0.157  -0.275  -0.195  -0.232
157   R         2.025   2.066   2.144   2.248   2.312   2.438   2.279   2.348   2.482
158   D         0.600   0.625   0.704   0.225   0.255   0.377   0.189   0.225   0.338
159   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
160   I        -0.054  -0.120  -0.059  -0.131  -0.197  -0.106  -0.275  -0.350  -0.271
161   A         0.241   0.152   0.082   0.348   0.212   0.132   0.189   0.054  -0.052
162   F        -0.529  -0.568  -0.621  -0.319  -0.405  -0.501  -0.508  -0.556  -0.605
163   P         2.025   2.066   2.144   2.052   2.110   2.238   2.279   2.348   2.482
164   K         1.099   0.976   0.960   1.044   0.868   0.844   1.118   0.900   0.843
165   M         0.716   0.692   0.736   0.736   0.657   0.694   0.421   0.360   0.403
166   K        -0.709  -0.748  -0.689  -0.871  -0.911  -0.802  -0.740  -0.774  -0.688
167   K        -0.054  -0.041  -0.058  -0.213  -0.196  -0.204  -0.275  -0.268  -0.275
168   K         2.025   2.066   2.144   1.902   1.958   2.085   2.279   2.348   2.482
169   G         2.025   2.066   2.144   2.251   2.307   2.441   2.279   2.348   2.482
170   A        -0.709  -0.748  -0.694  -0.767  -0.815  -0.711  -0.740  -0.774  -0.694
171   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
172   L         0.641   0.666   0.726   0.134   0.164   0.241   0.273   0.308   0.382
173   P         0.716   0.775   0.789   0.535   0.630   0.630   0.421   0.523   0.510
174   A        -1.184  -1.115  -1.133  -0.949  -0.827  -0.877  -0.972  -0.894  -0.890
175   L        -0.054  -0.120  -0.059  -0.178  -0.258  -0.156  -0.275  -0.350  -0.271
176   E        -0.529  -0.568  -0.621  -0.653  -0.735  -0.841  -0.508  -0.556  -0.605
177   V        -0.054  -0.123  -0.046  -0.340  -0.449  -0.337  -0.275  -0.356  -0.256
178   L         0.241   0.315   0.140   0.253   0.359   0.124   0.189   0.300   0.035
179   N        -0.709  -0.675  -0.672  -0.736  -0.663  -0.657  -0.740  -0.698  -0.670
180   D        -1.184  -1.195  -1.153  -1.174  -1.170  -1.134  -0.972  -0.978  -0.909
181   E         1.099   1.171   0.996   1.060   1.166   0.905   1.118   1.238   0.910
182   L         1.099   0.976   0.960   1.060   0.899   0.881   1.118   0.900   0.843
183   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
184   H        -1.184  -1.194  -1.146  -0.866  -0.910  -0.813  -0.972  -0.978  -0.903
185   Q        -0.054  -0.049  -0.046  -0.229  -0.246  -0.213  -0.275  -0.277  -0.260
186   D        -0.054   0.004  -0.039  -0.004   0.088   0.019  -0.275  -0.192  -0.245
187   Y        -1.184  -1.197  -1.159  -0.994  -1.016  -0.986  -0.972  -0.980  -0.914
188   K        -0.529  -0.564  -0.594  -0.585  -0.660  -0.691  -0.508  -0.551  -0.572
189   A        -1.184  -1.197  -1.168  -1.145  -1.144  -1.108  -0.972  -0.980  -0.923
190   K        -1.184  -1.195  -1.153  -1.091  -1.138  -1.024  -0.972  -0.978  -0.909
191   M        -1.184  -1.200  -1.171  -1.185  -1.215  -1.147  -0.972  -0.983  -0.926
192   H        -1.184  -1.195  -1.144  -0.876  -0.904  -0.820  -0.972  -0.979  -0.901
193   K        -0.714  -0.631  -0.662  -0.930  -0.780  -0.874  -0.730  -0.626  -0.653
194   I         0.071   0.005   0.006  -0.034  -0.116  -0.143  -0.062  -0.164  -0.167
195   I        -1.284  -1.270  -1.204  -1.220  -1.174  -1.099  -1.065  -1.045  -0.955
196   E        -1.184  -1.197  -1.168  -1.132  -1.165  -1.130  -0.972  -0.980  -0.923
197   E        -1.184  -1.200  -1.171  -1.090  -1.132  -1.087  -0.972  -0.983  -0.926
198   E         0.241   0.153   0.084   0.172   0.026  -0.107   0.189   0.055  -0.050
199   A        -1.184  -1.200  -1.171  -0.849  -0.912  -0.822  -0.972  -0.983  -0.926
200   G        -1.184  -1.200  -1.171  -1.162  -1.169  -1.119  -0.972  -0.983  -0.926
201   D        -0.709  -0.741  -0.690  -0.718  -0.788  -0.711  -0.740  -0.767  -0.689
202   P        -0.054  -0.120  -0.059  -0.279  -0.380  -0.302  -0.275  -0.350  -0.271
203   M        -1.184  -1.200  -1.171  -1.077  -1.067  -1.019  -0.972  -0.983  -0.926
204   S        -0.054  -0.042  -0.057  -0.333  -0.338  -0.369  -0.275  -0.269  -0.274
205   I        -0.709  -0.748  -0.689  -0.971  -0.990  -0.932  -0.740  -0.774  -0.688
206   L        -0.709  -0.743  -0.677  -0.937  -0.987  -0.868  -0.740  -0.770  -0.676
207   R        -0.709  -0.748  -0.673  -0.661  -0.729  -0.600  -0.740  -0.774  -0.672
208   G        -1.184  -1.121  -1.140  -1.254  -1.148  -1.196  -0.972  -0.901  -0.896
209   R         0.241   0.162   0.089   0.487   0.353   0.213   0.189   0.068  -0.042
210   N        -0.709  -0.670  -0.668  -0.677  -0.629  -0.630  -0.740  -0.693  -0.667
211   D         0.241   0.326   0.116   0.322   0.443   0.132   0.189   0.318  -0.002
212   D        -1.184  -1.195  -1.153  -1.183  -1.192  -1.144  -0.972  -0.978  -0.909
213   G        -0.144  -0.187  -0.095  -0.189  -0.227  -0.086  -0.396  -0.445  -0.323
214   D        -0.714  -0.665  -0.662  -0.565  -0.484  -0.491  -0.730  -0.667  -0.653
215   D         0.071   0.187   0.051   0.045   0.219   0.007  -0.062   0.112  -0.099
216   N        -0.714  -0.665  -0.662  -0.894  -0.811  -0.829  -0.730  -0.667  -0.653
217   N        -0.714  -0.751  -0.699  -0.918  -0.994  -0.918  -0.730  -0.770  -0.695
218   D         0.071   0.133   0.043  -0.017   0.076  -0.084  -0.062   0.031  -0.111
219   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
222   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
223   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
224   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
228   D        -0.144  -0.101  -0.081  -0.338  -0.296  -0.235  -0.396  -0.342  -0.305
229   D        -1.284  -1.269  -1.204  -0.962  -0.937  -0.835  -1.065  -1.045  -0.955
230   G         0.996   1.079   0.953   1.291   1.404   1.244   0.941   1.081   0.831
231   T        -0.529  -0.585  -0.603  -0.464  -0.567  -0.561  -0.508  -0.575  -0.583
232   L         1.099   0.976   0.960   1.011   0.831   0.796   1.118   0.900   0.843
233   P         2.025   2.066   2.144   2.052   2.110   2.238   2.279   2.348   2.482
234   P         0.071   0.079  -0.013   0.089   0.100  -0.069  -0.062  -0.048  -0.194
235   L         2.025   2.066   2.144   1.874   1.931   2.056   2.279   2.348   2.482
236   F        -0.144  -0.125  -0.101  -0.071  -0.038  -0.033  -0.396  -0.370  -0.329
237   P         0.641   0.662   0.725   0.455   0.480   0.573   0.273   0.298   0.381
238   I         0.996   1.018   0.907   0.775   0.802   0.605   0.941   0.975   0.743
239   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
240   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
241   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
242   -        -0.113  -0.123  -0.072  -0.264  -0.314  -0.214  -0.333  -0.351  -0.283
243   E        -0.529  -0.445  -0.564  -0.328  -0.194  -0.380  -0.508  -0.396  -0.535
244   N        -1.184  -1.121  -1.140  -1.326  -1.225  -1.265  -0.972  -0.901  -0.896
245   K        -0.054  -0.049  -0.046  -0.133  -0.160  -0.155  -0.275  -0.277  -0.260
246   I        -1.184  -1.115  -1.134  -1.273  -1.167  -1.200  -0.972  -0.895  -0.891
247   S        -1.184  -1.195  -1.153  -0.907  -0.931  -0.832  -0.972  -0.978  -0.909
248   G         0.241   0.304   0.124   0.291   0.374   0.148   0.189   0.285   0.011
249   A         0.241   0.304   0.124   0.365   0.454   0.188   0.189   0.285   0.011
250   K         0.996   1.026   0.906   0.820   0.860   0.647   0.941   0.989   0.741
251   I         2.025   2.066   2.144   1.829   1.886   2.011   2.279   2.348   2.482
252   E         0.641   0.663   0.715   0.438   0.467   0.556   0.273   0.302   0.361
253   E         2.025   2.066   2.144   1.929   1.987   2.113   2.279   2.348   2.482
254   I         2.025   2.066   2.144   1.829   1.886   2.011   2.279   2.348   2.482
255   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
256   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
257   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
258   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
259   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
260   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
261   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
262   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
263   N        -0.054   0.005  -0.036  -0.185  -0.095  -0.161  -0.275  -0.190  -0.242
264   L        -0.054  -0.042  -0.057  -0.259  -0.257  -0.240  -0.275  -0.269  -0.274
265   K        -1.184  -1.115  -1.134  -0.926  -0.823  -0.851  -0.972  -0.895  -0.891
266   Q        -0.054  -0.123  -0.050  -0.187  -0.284  -0.165  -0.275  -0.355  -0.261
267   A        -1.184  -1.194  -1.146  -1.021  -1.011  -0.940  -0.972  -0.978  -0.903
268   P        -0.054   0.007  -0.023  -0.242  -0.140  -0.193  -0.275  -0.186  -0.220
269   A        -1.659  -1.649  -1.583  -1.374  -1.339  -1.256  -1.204  -1.189  -1.098
270   P         0.241   0.332   0.130   0.292   0.427   0.096   0.189   0.326   0.020
271   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
272   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
273   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
274   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
275   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
276   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
277   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
278   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
279   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
280   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
281   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
282   A         1.099   1.153   0.994   1.067   1.139   0.935   1.118   1.208   0.907
283   P        -1.184  -1.197  -1.159  -1.180  -1.204  -1.157  -0.972  -0.980  -0.914
284   A        -0.054  -0.126  -0.049  -0.213  -0.330  -0.201  -0.275  -0.360  -0.259
285   P        -0.709  -0.748  -0.673  -0.594  -0.636  -0.513  -0.740  -0.774  -0.673
286   H        -1.659  -1.649  -1.583  -1.499  -1.497  -1.383  -1.204  -1.189  -1.098
287   E        -0.054   0.007  -0.023  -0.310  -0.221  -0.248  -0.275  -0.187  -0.223
288   Q        -1.184  -1.200  -1.171  -1.149  -1.191  -1.142  -0.972  -0.983  -0.926
289   Q         0.241   0.326   0.116   0.556   0.685   0.359   0.189   0.318  -0.002
290   E        -0.529  -0.576  -0.604  -0.523  -0.585  -0.625  -0.508  -0.565  -0.584
291   D        -0.529  -0.455  -0.588  -0.600  -0.477  -0.712  -0.508  -0.408  -0.564
292   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
293   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
294   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
295   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
296   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
297   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
298   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
299   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
300   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
301   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
302   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
303   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
304   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
305   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
306   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
307   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
308   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
309   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
310   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
311   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
312   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
313   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
314   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
315   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
316   V        -0.825  -0.813  -0.740  -1.139  -1.134  -1.015  -0.856  -0.837  -0.740
317   P        -0.054  -0.001  -0.032  -0.414  -0.311  -0.375  -0.275  -0.195  -0.232
318   E        -0.709  -0.662  -0.671  -0.757  -0.677  -0.690  -0.740  -0.685  -0.670
319   Y         1.099   0.976   0.960   1.470   1.313   1.297   1.118   0.900   0.843
320   E        -0.709  -0.670  -0.665  -0.827  -0.776  -0.744  -0.740  -0.693  -0.664
321   V        -0.054  -0.038  -0.043  -0.281  -0.282  -0.304  -0.275  -0.264  -0.256
322   K        -1.184  -1.202  -1.148  -1.096  -1.111  -1.036  -0.972  -0.984  -0.905
323   M        -0.054  -0.120  -0.059   0.103  -0.015   0.074  -0.275  -0.350  -0.271
324   K         0.241   0.167   0.088   0.283   0.174   0.086   0.189   0.075  -0.044
325   R         0.241   0.314   0.132   0.256   0.357   0.110   0.189   0.299   0.022
326   F        -0.709  -0.671  -0.660  -0.820  -0.753  -0.732  -0.740  -0.694  -0.659
327   K        -0.529  -0.449  -0.567  -0.595  -0.476  -0.661  -0.508  -0.400  -0.539
328   G        -1.184  -1.202  -1.148  -1.068  -1.088  -1.009  -0.972  -0.984  -0.905
329   A        -1.184  -1.121  -1.140  -0.950  -0.864  -0.873  -0.972  -0.901  -0.896
330   A        -1.284  -1.287  -1.204  -1.118  -1.118  -0.994  -1.065  -1.060  -0.955
331   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
332   K        -0.714  -0.707  -0.690  -0.822  -0.811  -0.781  -0.730  -0.716  -0.686
333   L         0.996   1.037   0.911   0.899   0.956   0.777   0.941   1.009   0.750
334   R        -0.144  -0.138  -0.091  -0.227  -0.214  -0.141  -0.396  -0.385  -0.317
335   I        -0.144  -0.130  -0.105  -0.474  -0.458  -0.441  -0.396  -0.377  -0.334
336   L        -0.714  -0.717  -0.677  -1.072  -1.087  -1.046  -0.730  -0.728  -0.671
337   I         0.071   0.079  -0.013  -0.063  -0.053  -0.180  -0.062  -0.048  -0.194
338   E         0.869   0.918   0.851   0.804   0.876   0.774   0.711   0.794   0.633
339   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
340   K        -0.709  -0.668  -0.662  -0.673  -0.633  -0.599  -0.740  -0.690  -0.661
341   A        -0.709  -0.743  -0.683  -0.570  -0.622  -0.500  -0.740  -0.770  -0.683
342   P        -1.659  -1.649  -1.583  -1.597  -1.530  -1.482  -1.204  -1.189  -1.098
343   N        -0.709  -0.668  -0.661  -0.833  -0.751  -0.753  -0.740  -0.691  -0.660
344   S        -1.659  -1.649  -1.583  -1.425  -1.417  -1.307  -1.204  -1.189  -1.098
345   K        -0.709  -0.743  -0.677  -0.990  -1.039  -0.948  -0.740  -0.770  -0.676
346   P        -1.184  -1.197  -1.168  -1.034  -1.046  -0.990  -0.972  -0.980  -0.923
347   D        -1.284  -1.270  -1.204  -1.183  -1.145  -1.060  -1.065  -1.045  -0.955
348   R        -1.184  -1.197  -1.168  -1.130  -1.172  -1.106  -0.972  -0.980  -0.923
349   F        -0.709  -0.667  -0.663  -0.746  -0.695  -0.681  -0.740  -0.691  -0.661
350   S        -0.709  -0.742  -0.683  -0.741  -0.807  -0.696  -0.740  -0.769  -0.683
351   P        -0.529  -0.576  -0.604  -0.660  -0.723  -0.795  -0.508  -0.565  -0.584
352   S        -1.184  -1.195  -1.153  -1.110  -1.137  -1.057  -0.972  -0.978  -0.909
353   Y         1.099   0.976   0.960   1.444   1.278   1.254   1.118   0.900   0.843
354   N        -0.529  -0.450  -0.582  -0.480  -0.360  -0.571  -0.508  -0.401  -0.557
355   F        -1.184  -1.115  -1.134  -0.946  -0.851  -0.861  -0.972  -0.895  -0.891
356   A        -1.184  -1.115  -1.134  -1.085  -0.962  -1.023  -0.972  -0.895  -0.891
357   E        -0.529  -0.585  -0.603  -0.476  -0.554  -0.592  -0.508  -0.575  -0.583
358   N        -0.529  -0.568  -0.621  -0.337  -0.412  -0.483  -0.508  -0.556  -0.605
359   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
360   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
361   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
362   I        -1.659  -1.649  -1.583  -1.763  -1.754  -1.652  -1.204  -1.189  -1.098
363   L         1.099   1.154   0.994   0.983   1.070   0.809   1.118   1.210   0.908
364   Y        -0.709  -0.669  -0.662  -0.838  -0.760  -0.757  -0.740  -0.691  -0.661
365   I        -0.709  -0.743  -0.673  -0.922  -0.934  -0.846  -0.740  -0.770  -0.672
366   N        -0.054  -0.004  -0.025  -0.202  -0.131  -0.139  -0.275  -0.201  -0.226
367   G        -0.054  -0.044  -0.045  -0.023  -0.010  -0.008  -0.275  -0.272  -0.259
368   -         0.071   0.143   0.022  -0.042   0.066  -0.144  -0.062   0.047  -0.143
369   -         0.071   0.146   0.028   0.189   0.305   0.117  -0.062   0.051  -0.134
370   -         0.071   0.134   0.046  -0.089   0.008  -0.141  -0.062   0.033  -0.107
371   -        -1.284  -1.272  -1.204  -1.220  -1.229  -1.098  -1.065  -1.047  -0.955
372   -        -0.714  -0.645  -0.662  -0.786  -0.678  -0.701  -0.730  -0.642  -0.653
373   -         0.071   0.021   0.011   0.371   0.274   0.267  -0.062  -0.141  -0.158
374   -        -1.284  -1.272  -1.204  -1.149  -1.115  -1.026  -1.065  -1.047  -0.955
375   -        -1.284  -1.272  -1.204  -1.197  -1.205  -1.075  -1.065  -1.047  -0.955
376   -         0.071   0.021   0.011  -0.068  -0.162  -0.173  -0.062  -0.141  -0.158
377   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
378   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
379   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
380   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
381   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
382   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
383   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
384   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
385   K        -0.529  -0.449  -0.567  -0.585  -0.470  -0.649  -0.508  -0.400  -0.539
386   L         0.241   0.153   0.084   0.280   0.168   0.082   0.189   0.055  -0.050
387   S        -0.709  -0.748  -0.694  -0.934  -0.977  -0.897  -0.740  -0.774  -0.694
388   I         0.716   0.692   0.736   0.421   0.377   0.430   0.421   0.360   0.403
389   P         2.025   2.066   2.144   2.052   2.110   2.238   2.279   2.348   2.482
390   L         1.099   1.165   1.002   1.026   1.122   0.890   1.118   1.228   0.922
391   P         0.241   0.162   0.089   0.362   0.248   0.129   0.189   0.068  -0.042
392   R        -1.184  -1.195  -1.144  -1.078  -1.122  -1.026  -0.972  -0.979  -0.901
393   D         0.869   0.797   0.833   0.771   0.626   0.671   0.711   0.566   0.598
394   I         0.869   0.797   0.833   0.800   0.700   0.748   0.711   0.566   0.598
395   V        -0.529  -0.576  -0.604  -0.615  -0.705  -0.737  -0.508  -0.565  -0.584
396   V        -0.709  -0.742  -0.683  -0.740  -0.813  -0.731  -0.740  -0.769  -0.683
397   N        -0.529  -0.577  -0.593  -0.337  -0.402  -0.438  -0.508  -0.566  -0.571
398   A        -1.184  -1.202  -1.148  -1.036  -1.092  -0.987  -0.972  -0.984  -0.905
399   A        -0.825  -0.817  -0.740  -0.967  -0.957  -0.840  -0.856  -0.841  -0.740
400   D        -0.113  -0.115  -0.086  -0.159  -0.152  -0.112  -0.333  -0.339  -0.303
401   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
402   I        -1.184  -1.122  -1.131  -0.973  -0.856  -0.899  -0.972  -0.902  -0.888
403   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
404   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
405   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
406   K        -0.054   0.005  -0.036  -0.333  -0.237  -0.306  -0.275  -0.190  -0.242
407   I        -0.709  -0.742  -0.677  -0.684  -0.712  -0.619  -0.740  -0.769  -0.676
408   F         1.099   0.976   0.960   1.389   1.229   1.210   1.118   0.900   0.843
409   H        -1.184  -1.195  -1.144  -0.769  -0.823  -0.706  -0.972  -0.979  -0.901
410   I         1.099   1.153   0.994   1.183   1.258   1.009   1.118   1.208   0.907
411   R        -0.714  -0.706  -0.682  -0.573  -0.541  -0.540  -0.730  -0.720  -0.677
412   K         0.641   0.682   0.729   0.298   0.357   0.423   0.273   0.339   0.389
413   E         0.241   0.315   0.140   0.335   0.437   0.217   0.189   0.300   0.035
414   R        -0.709  -0.670  -0.665  -0.358  -0.291  -0.277  -0.740  -0.693  -0.664
415   T        -0.529  -0.564  -0.594  -0.342  -0.431  -0.469  -0.508  -0.551  -0.572
416   L         0.716   0.690   0.740   0.542   0.503   0.588   0.421   0.356   0.412
417   Y        -0.529  -0.573  -0.613  -0.155  -0.200  -0.294  -0.508  -0.561  -0.595
418   I         2.025   2.066   2.144   1.877   1.950   2.060   2.279   2.348   2.482
419   Y         1.099   1.153   0.994   1.389   1.471   1.262   1.118   1.208   0.907
420   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
421   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
422   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
423   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
424   I        -0.709  -0.742  -0.683  -0.909  -0.944  -0.840  -0.740  -0.769  -0.683
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P38768
Output conservation file - output/P38768
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
