1     M         1.154   1.156   1.191   1.409   1.411   1.456   1.224   1.226   1.273
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    N        -1.387  -1.359  -1.354  -1.292  -1.253  -1.241  -1.232  -1.201  -1.161
13    I        -1.387  -1.385  -1.341  -1.345  -1.331  -1.259  -1.232  -1.229  -1.148
14    G        -1.387  -1.368  -1.341  -1.318  -1.287  -1.262  -1.232  -1.212  -1.148
15    G        -0.829  -0.826  -0.804  -0.834  -0.830  -0.806  -0.908  -0.903  -0.861
16    G        -1.490  -1.488  -1.375  -1.504  -1.500  -1.324  -1.334  -1.330  -1.181
17    K        -1.387  -1.394  -1.357  -1.415  -1.431  -1.346  -1.232  -1.238  -1.164
18    -        -0.829  -0.842  -0.818  -1.058  -1.085  -1.015  -0.908  -0.924  -0.878
19    -         0.082   0.099  -0.008   0.121   0.149  -0.039  -0.055  -0.027  -0.216
20    -         0.082   0.099  -0.008  -0.083  -0.054  -0.238  -0.055  -0.027  -0.216
21    -        -0.829  -0.842  -0.809  -0.875  -0.885  -0.817  -0.908  -0.924  -0.867
22    -        -0.829  -0.807  -0.801  -0.909  -0.877  -0.845  -0.908  -0.878  -0.857
23    -        -1.490  -1.486  -1.375  -1.545  -1.550  -1.363  -1.334  -1.329  -1.181
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    -        -0.829  -0.810  -0.804  -0.669  -0.639  -0.641  -0.908  -0.882  -0.861
30    F        -1.387  -1.359  -1.354  -1.369  -1.332  -1.291  -1.232  -1.201  -1.161
31    L        -1.387  -1.388  -1.348  -1.354  -1.348  -1.310  -1.232  -1.231  -1.155
32    L         1.154   1.156   1.191   0.947   0.950   1.015   1.224   1.226   1.273
33    G         0.200   0.193   0.020   0.268   0.258  -0.010   0.132   0.121  -0.168
34    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    R         0.200   0.193   0.020   0.365   0.355   0.044   0.132   0.121  -0.168
37    I        -1.387  -1.384  -1.346  -1.225  -1.218  -1.185  -1.232  -1.228  -1.153
38    S         0.200   0.193   0.020   0.277   0.266   0.004   0.132   0.121  -0.168
39    N         1.154   1.156   1.191   1.151   1.153   1.210   1.224   1.226   1.273
40    N         1.154   1.156   1.191   1.151   1.153   1.210   1.224   1.226   1.273
41    P        -0.129  -0.121  -0.077  -0.392  -0.380  -0.288  -0.413  -0.399  -0.336
42    T        -0.658  -0.650  -0.761  -0.522  -0.513  -0.696  -0.686  -0.675  -0.807
43    S        -0.658  -0.694  -0.780  -0.647  -0.708  -0.876  -0.686  -0.732  -0.830
44    G         1.154   1.156   1.191   1.166   1.169   1.225   1.224   1.226   1.273
45    I        -0.658  -0.694  -0.780  -0.742  -0.799  -0.956  -0.686  -0.732  -0.830
46    V         1.154   1.156   1.191   1.200   1.200   1.256   1.224   1.226   1.273
47    G         1.154   1.156   1.191   1.166   1.169   1.225   1.224   1.226   1.273
48    L         1.154   1.156   1.191   0.947   0.950   1.015   1.224   1.226   1.273
49    A         1.154   1.156   1.191   1.210   1.212   1.266   1.224   1.226   1.273
50    N         1.154   1.156   1.191   1.151   1.153   1.210   1.224   1.226   1.273
51    V         1.154   1.156   1.191   1.200   1.200   1.256   1.224   1.226   1.273
52    G         1.154   1.156   1.191   1.166   1.169   1.225   1.224   1.226   1.273
53    K         1.154   1.156   1.191   1.034   1.038   1.098   1.224   1.226   1.273
54    S         1.154   1.156   1.191   1.169   1.171   1.227   1.224   1.226   1.273
55    T         1.154   1.156   1.191   1.225   1.226   1.280   1.224   1.226   1.273
56    F         1.154   1.156   1.191   1.285   1.289   1.338   1.224   1.226   1.273
57    F         1.154   1.156   1.191   1.285   1.289   1.338   1.224   1.226   1.273
58    Q         1.154   1.156   1.191   1.308   1.310   1.359   1.224   1.226   1.273
59    A         0.200   0.193   0.020   0.317   0.306   0.039   0.132   0.121  -0.168
60    I        -0.658  -0.694  -0.780  -0.672  -0.723  -0.853  -0.686  -0.732  -0.830
61    T         1.154   1.156   1.191   1.225   1.226   1.280   1.224   1.226   1.273
62    N        -0.129  -0.121  -0.077  -0.407  -0.392  -0.314  -0.413  -0.399  -0.336
63    S         0.200   0.174   0.016   0.277   0.239  -0.004   0.132   0.092  -0.176
64    K        -1.387  -1.412  -1.354  -1.317  -1.348  -1.231  -1.232  -1.256  -1.161
65    L         1.154   1.156   1.191   0.947   0.950   1.015   1.224   1.226   1.273
66    G         1.154   1.156   1.191   1.166   1.169   1.225   1.224   1.226   1.273
67    N        -0.129  -0.138  -0.087  -0.263  -0.280  -0.195  -0.413  -0.428  -0.355
68    P        -0.129  -0.138  -0.087  -0.145  -0.162  -0.094  -0.413  -0.428  -0.355
69    A         1.154   1.156   1.191   1.210   1.212   1.266   1.224   1.226   1.273
70    N         1.154   1.156   1.191   1.151   1.153   1.210   1.224   1.226   1.273
71    Y         1.154   1.156   1.191   1.345   1.346   1.395   1.224   1.226   1.273
72    P         1.154   1.156   1.191   1.300   1.303   1.352   1.224   1.226   1.273
73    F         0.200   0.193   0.020   0.420   0.412   0.156   0.132   0.121  -0.168
74    A         1.154   1.156   1.191   1.210   1.212   1.266   1.224   1.226   1.273
75    T         1.154   1.156   1.191   1.225   1.226   1.280   1.224   1.226   1.273
76    I         1.154   1.156   1.191   1.071   1.074   1.133   1.224   1.226   1.273
77    D        -0.129  -0.126  -0.080  -0.292  -0.285  -0.222  -0.413  -0.407  -0.342
78    A         0.200   0.232   0.029   0.402   0.448   0.128   0.132   0.183  -0.153
79    E         0.200   0.174   0.016   0.207   0.173  -0.072   0.132   0.092  -0.176
80    C        -1.387  -1.384  -1.346  -1.300  -1.303  -1.222  -1.232  -1.228  -1.153
81    A        -0.129  -0.121  -0.077  -0.257  -0.243  -0.173  -0.413  -0.399  -0.336
82    K        -0.658  -0.694  -0.780  -0.822  -0.881  -1.051  -0.686  -0.732  -0.830
83    V         1.154   1.156   1.191   1.200   1.200   1.256   1.224   1.226   1.273
84    N        -1.387  -1.384  -1.346  -1.450  -1.446  -1.382  -1.232  -1.228  -1.153
85    I        -0.129  -0.121  -0.077  -0.309  -0.294  -0.232  -0.413  -0.399  -0.336
86    P         0.200   0.174   0.016   0.377   0.339   0.059   0.132   0.092  -0.176
87    S         1.154   1.156   1.191   1.169   1.171   1.227   1.224   1.226   1.273
88    V        -1.387  -1.365  -1.339  -1.146  -1.112  -1.084  -1.232  -1.208  -1.146
89    P        -0.658  -0.639  -0.770  -0.694  -0.666  -0.848  -0.686  -0.661  -0.817
90    L         1.154   1.156   1.191   0.947   0.950   1.015   1.224   1.226   1.273
91    S        -1.916  -1.912  -1.788  -1.696  -1.692  -1.508  -1.505  -1.500  -1.344
92    N        -0.658  -0.639  -0.770  -0.378  -0.347  -0.594  -0.686  -0.661  -0.817
93    L         0.200   0.181   0.022   0.089   0.066  -0.135   0.132   0.104  -0.165
94    L        -1.916  -1.912  -1.788  -1.703  -1.693  -1.514  -1.505  -1.500  -1.344
95    R        -0.658  -0.654  -0.760  -0.626  -0.618  -0.740  -0.686  -0.680  -0.805
96    I         0.200   0.232   0.029   0.017   0.066  -0.247   0.132   0.183  -0.153
97    Y         1.154   1.156   1.191   1.345   1.346   1.395   1.224   1.226   1.273
98    Q        -0.858  -0.866  -0.819  -0.876  -0.888  -0.813  -0.959  -0.966  -0.881
99    S         1.154   1.156   1.191   1.169   1.171   1.227   1.224   1.226   1.273
100   A        -0.658  -0.639  -0.770  -0.446  -0.417  -0.646  -0.686  -0.661  -0.817
101   K         1.154   1.156   1.191   1.034   1.038   1.098   1.224   1.226   1.273
102   C        -1.916  -1.912  -1.788  -1.685  -1.685  -1.497  -1.505  -1.500  -1.344
103   V        -0.129  -0.125  -0.081  -0.347  -0.339  -0.262  -0.413  -0.405  -0.344
104   P         1.154   1.156   1.191   1.300   1.303   1.352   1.224   1.226   1.273
105   G        -0.858  -0.840  -0.818  -0.863  -0.838  -0.796  -0.959  -0.938  -0.880
106   T        -1.387  -1.412  -1.354  -1.307  -1.354  -1.275  -1.232  -1.256  -1.161
107   L         1.154   1.156   1.191   0.947   0.950   1.015   1.224   1.226   1.273
108   T        -0.658  -0.656  -0.767  -0.541  -0.540  -0.732  -0.686  -0.683  -0.815
109   I         1.154   1.156   1.191   1.071   1.074   1.133   1.224   1.226   1.273
110   Y        -1.387  -1.394  -1.357  -1.110  -1.126  -1.086  -1.232  -1.238  -1.164
111   D         1.154   1.156   1.191   1.197   1.198   1.254   1.224   1.226   1.273
112   I         1.154   1.156   1.191   1.071   1.074   1.133   1.224   1.226   1.273
113   A         1.154   1.156   1.191   1.210   1.212   1.266   1.224   1.226   1.273
114   G         1.154   1.156   1.191   1.166   1.169   1.225   1.224   1.226   1.273
115   L         1.154   1.156   1.191   0.947   0.950   1.015   1.224   1.226   1.273
116   T         0.200   0.181   0.022   0.326   0.297   0.045   0.132   0.104  -0.165
117   R         1.154   1.156   1.191   1.305   1.308   1.357   1.224   1.226   1.273
118   G        -0.129  -0.141  -0.083  -0.292  -0.315  -0.223  -0.413  -0.433  -0.348
119   A         1.154   1.156   1.191   1.210   1.212   1.266   1.224   1.226   1.273
120   S         0.200   0.174   0.016   0.273   0.236  -0.011   0.132   0.092  -0.176
121   Q        -0.658  -0.639  -0.770  -0.564  -0.538  -0.738  -0.686  -0.661  -0.817
122   G         1.154   1.156   1.191   1.166   1.169   1.225   1.224   1.226   1.273
123   H        -0.858  -0.866  -0.819  -0.804  -0.815  -0.744  -0.959  -0.966  -0.881
124   G         1.154   1.156   1.191   1.166   1.169   1.225   1.224   1.226   1.273
125   L         1.154   1.156   1.191   0.947   0.950   1.015   1.224   1.226   1.273
126   G         1.154   1.156   1.191   1.166   1.169   1.225   1.224   1.226   1.273
127   N         1.154   1.156   1.191   1.151   1.153   1.210   1.224   1.226   1.273
128   K         1.154   1.156   1.191   1.034   1.038   1.098   1.224   1.226   1.273
129   F         1.154   1.156   1.191   1.285   1.289   1.338   1.224   1.226   1.273
130   L         1.154   1.156   1.191   0.947   0.950   1.015   1.224   1.226   1.273
131   N        -0.129  -0.138  -0.087  -0.295  -0.313  -0.231  -0.413  -0.428  -0.355
132   D         1.154   1.156   1.191   1.197   1.198   1.254   1.224   1.226   1.273
133   I         1.154   1.156   1.191   1.071   1.074   1.133   1.224   1.226   1.273
134   R         1.154   1.156   1.191   1.305   1.308   1.357   1.224   1.226   1.273
135   H        -0.129  -0.141  -0.083  -0.016  -0.037   0.040  -0.413  -0.433  -0.348
136   V         1.154   1.156   1.191   1.200   1.200   1.256   1.224   1.226   1.273
137   E         0.200   0.232   0.029   0.275   0.322  -0.007   0.132   0.183  -0.153
138   G         1.154   1.156   1.191   1.166   1.169   1.225   1.224   1.226   1.273
139   I         1.154   1.156   1.191   1.071   1.074   1.133   1.224   1.226   1.273
140   F        -0.658  -0.650  -0.761  -0.490  -0.481  -0.682  -0.686  -0.675  -0.807
141   Q         0.200   0.193   0.020   0.395   0.385   0.094   0.132   0.121  -0.168
142   V        -0.658  -0.680  -0.765  -0.659  -0.696  -0.882  -0.686  -0.713  -0.811
143   V         1.154   1.156   1.191   1.200   1.200   1.256   1.224   1.226   1.273
144   R         1.154   1.156   1.191   1.305   1.308   1.357   1.224   1.226   1.273
145   G         1.154   1.156   1.191   1.166   1.169   1.225   1.224   1.226   1.273
146   F         1.154   1.156   1.191   1.285   1.289   1.338   1.224   1.226   1.273
147   L        -1.916  -1.912  -1.788  -1.931  -1.911  -1.732  -1.505  -1.500  -1.344
148   K        -0.658  -0.609  -0.757  -0.609  -0.530  -0.794  -0.686  -0.621  -0.801
149   E        -0.129  -0.121  -0.077  -0.292  -0.277  -0.214  -0.413  -0.399  -0.336
150   D        -0.858  -0.861  -0.813  -0.962  -0.965  -0.879  -0.959  -0.960  -0.875
151   I         1.154   1.156   1.191   1.071   1.074   1.133   1.224   1.226   1.273
152   T        -0.658  -0.694  -0.780  -0.556  -0.615  -0.776  -0.686  -0.732  -0.830
153   H         1.154   1.156   1.191   1.389   1.393   1.437   1.224   1.226   1.273
154   I         1.154   1.156   1.191   1.071   1.074   1.133   1.224   1.226   1.273
155   E         1.154   1.156   1.191   1.105   1.109   1.166   1.224   1.226   1.273
156   G        -0.129  -0.141  -0.083  -0.266  -0.288  -0.194  -0.413  -0.433  -0.348
157   N         1.154   1.156   1.191   1.151   1.153   1.210   1.224   1.226   1.273
158   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
159   V         1.154   1.156   1.191   1.200   1.200   1.256   1.224   1.226   1.273
160   D         1.154   1.156   1.191   1.197   1.198   1.254   1.224   1.226   1.273
161   P         1.154   1.156   1.191   1.300   1.303   1.352   1.224   1.226   1.273
162   V         0.200   0.174   0.016   0.270   0.229  -0.044   0.132   0.092  -0.176
163   R         1.154   1.156   1.191   1.305   1.308   1.357   1.224   1.226   1.273
164   D         1.154   1.156   1.191   1.197   1.198   1.254   1.224   1.226   1.273
165   L         0.200   0.174   0.016   0.106   0.075  -0.114   0.132   0.092  -0.176
166   S        -0.658  -0.694  -0.780  -0.584  -0.641  -0.783  -0.686  -0.732  -0.830
167   V        -0.858  -0.841  -0.823  -1.058  -1.032  -1.014  -0.959  -0.940  -0.886
168   V         1.154   1.156   1.191   1.200   1.200   1.256   1.224   1.226   1.273
169   Q        -0.658  -0.694  -0.780  -0.446  -0.503  -0.664  -0.686  -0.732  -0.830
170   D         0.200   0.174   0.016   0.275   0.236  -0.032   0.132   0.092  -0.176
171   E         1.154   1.156   1.191   1.105   1.109   1.166   1.224   1.226   1.273
172   L         1.154   1.156   1.191   0.947   0.950   1.015   1.224   1.226   1.273
173   I         0.200   0.230   0.025   0.174   0.217  -0.086   0.132   0.179  -0.161
174   L         1.154   1.156   1.191   0.947   0.950   1.015   1.224   1.226   1.273
175   K         1.154   1.156   1.191   1.034   1.038   1.098   1.224   1.226   1.273
176   D         1.154   1.156   1.191   1.197   1.198   1.254   1.224   1.226   1.273
177   L         1.154   1.156   1.191   0.947   0.950   1.015   1.224   1.226   1.273
178   E         1.154   1.156   1.191   1.105   1.109   1.166   1.224   1.226   1.273
179   F        -0.658  -0.650  -0.761  -0.424  -0.415  -0.589  -0.686  -0.675  -0.807
180   L        -0.129  -0.109  -0.073  -0.495  -0.449  -0.403  -0.413  -0.377  -0.330
181   E         0.200   0.193   0.020   0.207   0.198  -0.065   0.132   0.121  -0.168
182   N        -1.387  -1.394  -1.357  -1.315  -1.328  -1.267  -1.232  -1.238  -1.164
183   I        -1.916  -1.912  -1.788  -1.846  -1.839  -1.651  -1.505  -1.500  -1.344
184   R        -0.129  -0.141  -0.083  -0.218  -0.244  -0.166  -0.413  -0.433  -0.348
185   E         1.154   1.156   1.191   1.105   1.109   1.166   1.224   1.226   1.273
186   R        -0.129  -0.138  -0.087  -0.238  -0.258  -0.201  -0.413  -0.428  -0.355
187   L        -1.387  -1.359  -1.354  -1.413  -1.358  -1.390  -1.232  -1.201  -1.161
188   S        -0.858  -0.870  -0.820  -0.944  -0.961  -0.872  -0.959  -0.970  -0.882
189   K         0.200   0.193   0.020   0.165   0.157  -0.079   0.132   0.121  -0.168
190   K        -0.658  -0.694  -0.780  -0.707  -0.759  -0.882  -0.686  -0.732  -0.830
191   M        -1.387  -1.385  -1.341  -1.305  -1.303  -1.289  -1.232  -1.229  -1.148
192   R        -0.858  -0.870  -0.820  -0.892  -0.912  -0.846  -0.959  -0.970  -0.882
193   M        -0.858  -0.866  -0.819  -0.714  -0.727  -0.679  -0.959  -0.966  -0.881
194   V        -1.387  -1.359  -1.354  -1.290  -1.243  -1.277  -1.232  -1.201  -1.161
195   S        -1.387  -1.394  -1.357  -1.180  -1.189  -1.116  -1.232  -1.238  -1.164
196   K        -0.129  -0.141  -0.083  -0.454  -0.475  -0.377  -0.413  -0.433  -0.348
197   N         0.082   0.005  -0.029   0.078  -0.048  -0.108  -0.055  -0.182  -0.253
198   S         1.154   1.156   1.191   1.197   1.201   1.254   1.224   1.226   1.273
199   K        -0.060  -0.081  -0.070  -0.234  -0.268  -0.232  -0.292  -0.329  -0.324
200   E         1.154   1.156   1.191   1.070   1.071   1.133   1.224   1.226   1.273
201   H        -1.916  -1.912  -1.788  -1.606  -1.609  -1.421  -1.505  -1.500  -1.344
202   Q        -1.387  -1.394  -1.357  -1.281  -1.289  -1.275  -1.232  -1.238  -1.164
203   E        -0.658  -0.694  -0.780  -0.604  -0.654  -0.774  -0.686  -0.732  -0.830
204   M        -0.858  -0.868  -0.815  -0.634  -0.652  -0.579  -0.959  -0.968  -0.877
205   K        -1.916  -1.912  -1.788  -1.720  -1.713  -1.531  -1.505  -1.500  -1.344
206   I        -0.858  -0.861  -0.813  -1.118  -1.119  -1.007  -0.959  -0.960  -0.875
207   E         0.200   0.181   0.022   0.195   0.170  -0.082   0.132   0.104  -0.165
208   T        -0.858  -0.840  -0.812  -1.142  -1.117  -1.033  -0.959  -0.939  -0.874
209   E        -1.387  -1.394  -1.357  -1.250  -1.259  -1.178  -1.232  -1.238  -1.164
210   L        -0.129  -0.141  -0.083  -0.438  -0.454  -0.343  -0.413  -0.433  -0.348
211   L         1.154   1.156   1.191   0.947   0.950   1.015   1.224   1.226   1.273
212   D        -1.387  -1.389  -1.343  -1.335  -1.338  -1.278  -1.232  -1.232  -1.150
213   A        -1.387  -1.368  -1.341  -1.386  -1.354  -1.296  -1.232  -1.212  -1.148
214   L         0.200   0.174   0.016   0.017  -0.019  -0.271   0.132   0.092  -0.176
215   E        -0.658  -0.694  -0.780  -0.604  -0.654  -0.774  -0.686  -0.732  -0.830
216   E        -1.387  -1.394  -1.357  -1.324  -1.335  -1.263  -1.232  -1.238  -1.164
217   H        -0.129  -0.141  -0.083  -0.212  -0.243  -0.175  -0.413  -0.433  -0.348
218   L         0.200   0.230   0.025   0.106   0.146  -0.102   0.132   0.179  -0.161
219   F         0.200   0.232   0.029   0.464   0.508   0.197   0.132   0.183  -0.153
220   N        -0.858  -0.840  -0.812  -0.962  -0.936  -0.879  -0.959  -0.939  -0.874
221   G         0.200   0.174   0.016   0.261   0.224  -0.031   0.132   0.092  -0.176
222   K        -0.858  -0.866  -0.819  -0.961  -0.970  -0.892  -0.959  -0.966  -0.881
223   K         0.200   0.193   0.020   0.165   0.157  -0.079   0.132   0.121  -0.168
224   I        -0.658  -0.650  -0.761  -0.742  -0.725  -0.923  -0.686  -0.675  -0.807
225   R        -0.658  -0.648  -0.755  -0.535  -0.523  -0.675  -0.686  -0.673  -0.799
226   H        -0.858  -0.868  -0.815  -0.768  -0.788  -0.703  -0.959  -0.968  -0.877
227   F         1.154   1.156   1.191   1.268   1.271   1.321   1.224   1.226   1.273
228   K         1.154   1.156   1.191   1.018   1.020   1.083   1.224   1.226   1.273
229   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
230   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
231   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
232   D        -1.387  -1.359  -1.354  -1.282  -1.241  -1.228  -1.232  -1.201  -1.161
233   H        -1.916  -1.912  -1.788  -1.675  -1.672  -1.487  -1.505  -1.500  -1.344
234   W         1.154   1.156   1.191   1.440   1.443   1.486   1.224   1.226   1.273
235   N        -0.858  -0.866  -0.819  -0.903  -0.916  -0.831  -0.959  -0.966  -0.881
236   L        -1.387  -1.359  -1.354  -1.405  -1.351  -1.380  -1.232  -1.201  -1.161
237   D        -0.858  -0.870  -0.820  -1.004  -1.022  -0.947  -0.959  -0.970  -0.882
238   E         1.154   1.156   1.191   1.105   1.109   1.166   1.224   1.226   1.273
239   V        -0.129  -0.125  -0.081  -0.347  -0.339  -0.262  -0.413  -0.405  -0.344
240   K        -0.129  -0.141  -0.083  -0.380  -0.398  -0.295  -0.413  -0.433  -0.348
241   I        -0.129  -0.136  -0.086  -0.347  -0.358  -0.268  -0.413  -0.425  -0.351
242   L        -0.129  -0.141  -0.083  -0.532  -0.551  -0.445  -0.413  -0.433  -0.348
243   N         0.200   0.193   0.020   0.280   0.269   0.023   0.132   0.121  -0.168
244   K        -1.387  -1.412  -1.354  -1.354  -1.386  -1.274  -1.232  -1.256  -1.161
245   H        -1.387  -1.412  -1.354  -1.165  -1.211  -1.157  -1.232  -1.256  -1.161
246   N         1.154   1.156   1.191   1.151   1.153   1.210   1.224   1.226   1.273
247   F         0.200   0.181   0.022   0.325   0.298  -0.007   0.132   0.104  -0.165
248   L         1.154   1.156   1.191   0.947   0.950   1.015   1.224   1.226   1.273
249   T         1.154   1.156   1.191   1.225   1.226   1.280   1.224   1.226   1.273
250   S         0.200   0.232   0.029   0.303   0.349   0.031   0.132   0.183  -0.153
251   K         1.154   1.156   1.191   1.034   1.038   1.098   1.224   1.226   1.273
252   P         1.154   1.156   1.191   1.300   1.303   1.352   1.224   1.226   1.273
253   T         0.200   0.193   0.020   0.318   0.306   0.029   0.132   0.121  -0.168
254   L        -0.129  -0.141  -0.083  -0.454  -0.470  -0.360  -0.413  -0.433  -0.348
255   I        -1.387  -1.359  -1.354  -1.183  -1.134  -1.165  -1.232  -1.201  -1.161
256   L         1.154   1.156   1.191   0.947   0.950   1.015   1.224   1.226   1.273
257   L         1.154   1.156   1.191   0.947   0.950   1.015   1.224   1.226   1.273
258   N         1.154   1.156   1.191   1.151   1.153   1.210   1.224   1.226   1.273
259   V         1.154   1.156   1.191   1.200   1.200   1.256   1.224   1.226   1.273
260   S        -0.658  -0.656  -0.767  -0.580  -0.580  -0.758  -0.686  -0.683  -0.815
261   P        -0.658  -0.694  -0.780  -0.525  -0.584  -0.776  -0.686  -0.732  -0.830
262   Q        -0.858  -0.840  -0.812  -1.022  -0.998  -0.916  -0.959  -0.939  -0.874
263   D         0.200   0.193   0.020   0.275   0.264  -0.023   0.132   0.121  -0.168
264   Y         1.154   1.156   1.191   1.345   1.346   1.395   1.224   1.226   1.273
265   V        -0.858  -0.866  -0.813  -1.090  -1.100  -1.000  -0.959  -0.966  -0.874
266   R        -1.916  -1.912  -1.788  -1.745  -1.735  -1.554  -1.505  -1.500  -1.344
267   N        -1.387  -1.384  -1.346  -1.305  -1.301  -1.278  -1.232  -1.228  -1.153
268   E        -1.387  -1.412  -1.354  -1.233  -1.263  -1.157  -1.232  -1.256  -1.161
269   N         0.200   0.193   0.020   0.246   0.234  -0.036   0.132   0.121  -0.168
270   K        -0.858  -0.868  -0.815  -0.948  -0.952  -0.868  -0.959  -0.968  -0.877
271   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
272   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
273   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
274   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
275   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
276   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
277   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
278   F         1.154   1.156   1.191   1.285   1.289   1.338   1.224   1.226   1.273
279   V        -1.916  -1.912  -1.788  -1.873  -1.862  -1.676  -1.505  -1.500  -1.344
280   R        -0.658  -0.654  -0.760  -0.626  -0.618  -0.740  -0.686  -0.680  -0.805
281   N        -1.387  -1.368  -1.341  -1.429  -1.395  -1.360  -1.232  -1.212  -1.148
282   I        -0.129  -0.109  -0.073  -0.309  -0.268  -0.224  -0.413  -0.377  -0.330
283   I        -1.916  -1.912  -1.788  -1.911  -1.898  -1.712  -1.505  -1.500  -1.344
284   E        -0.858  -0.841  -0.823  -0.866  -0.837  -0.801  -0.959  -0.940  -0.886
285   W         1.154   1.156   1.191   1.440   1.443   1.486   1.224   1.226   1.273
286   I         0.200   0.193   0.020   0.111   0.101  -0.204   0.132   0.121  -0.168
287   N        -1.916  -1.912  -1.788  -1.815  -1.814  -1.621  -1.505  -1.500  -1.344
288   E        -0.658  -0.694  -0.780  -0.622  -0.674  -0.800  -0.686  -0.732  -0.830
289   F        -0.858  -0.840  -0.818  -0.778  -0.759  -0.701  -0.959  -0.938  -0.880
290   S        -0.658  -0.656  -0.767  -0.486  -0.480  -0.626  -0.686  -0.683  -0.815
291   P         1.154   1.156   1.191   1.300   1.303   1.352   1.224   1.226   1.273
292   G        -0.129  -0.109  -0.073  -0.297  -0.260  -0.207  -0.413  -0.377  -0.330
293   D         1.154   1.156   1.191   1.197   1.198   1.254   1.224   1.226   1.273
294   K        -1.387  -1.389  -1.343  -1.495  -1.497  -1.419  -1.232  -1.232  -1.150
295   F        -0.658  -0.609  -0.757  -0.751  -0.681  -0.864  -0.686  -0.621  -0.801
296   L        -0.858  -0.842  -0.810  -1.070  -1.051  -0.948  -0.959  -0.941  -0.872
297   L        -0.858  -0.859  -0.822  -0.848  -0.830  -0.763  -0.959  -0.958  -0.884
298   F         1.154   1.156   1.191   1.285   1.289   1.338   1.224   1.226   1.273
299   S         1.154   1.156   1.191   1.169   1.171   1.227   1.224   1.226   1.273
300   A         1.154   1.156   1.191   1.210   1.212   1.266   1.224   1.226   1.273
301   E         0.200   0.174   0.016   0.200   0.165  -0.085   0.132   0.092  -0.176
302   F        -0.658  -0.609  -0.757  -0.453  -0.373  -0.651  -0.686  -0.621  -0.801
303   E         1.154   1.156   1.191   1.105   1.109   1.166   1.224   1.226   1.273
304   S        -0.658  -0.639  -0.770  -0.576  -0.549  -0.787  -0.686  -0.661  -0.817
305   Q        -1.387  -1.384  -1.346  -1.366  -1.364  -1.279  -1.232  -1.228  -1.153
306   L        -0.858  -0.870  -0.814  -0.993  -1.011  -0.922  -0.959  -0.970  -0.875
307   M        -0.658  -0.639  -0.770  -0.596  -0.573  -0.773  -0.686  -0.661  -0.817
308   E         1.154   1.156   1.191   1.095   1.101   1.156   1.224   1.226   1.273
309   C        -0.829  -0.801  -0.803  -0.643  -0.589  -0.643  -0.908  -0.871  -0.860
310   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
311   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
312   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
313   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
314   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
315   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
316   K        -0.829  -0.801  -0.803  -0.964  -0.923  -0.909  -0.908  -0.871  -0.860
317   G        -0.858  -0.870  -0.820  -0.925  -0.940  -0.847  -0.959  -0.970  -0.882
318   I        -1.387  -1.359  -1.354  -1.351  -1.298  -1.347  -1.232  -1.201  -1.161
319   A        -0.858  -0.841  -0.823  -1.025  -0.997  -0.984  -0.959  -0.940  -0.886
320   S        -0.858  -0.840  -0.818  -0.876  -0.854  -0.805  -0.959  -0.938  -0.880
321   E        -0.829  -0.865  -0.819  -0.946  -1.020  -0.930  -0.908  -0.954  -0.879
322   Y        -1.490  -1.480  -1.375  -1.203  -1.205  -1.036  -1.334  -1.322  -1.181
323   F        -0.829  -0.776  -0.801  -0.977  -0.893  -0.921  -0.908  -0.838  -0.857
324   D        -1.490  -1.480  -1.375  -1.401  -1.381  -1.226  -1.334  -1.322  -1.181
325   K        -0.829  -0.776  -0.801  -0.835  -0.742  -0.806  -0.908  -0.838  -0.857
326   I        -0.829  -0.776  -0.801  -0.753  -0.670  -0.711  -0.908  -0.838  -0.857
327   K        -0.829  -0.865  -0.819  -1.086  -1.159  -1.075  -0.908  -0.954  -0.879
328   E        -1.387  -1.412  -1.354  -1.360  -1.399  -1.301  -1.232  -1.256  -1.161
329   D        -1.387  -1.394  -1.357  -1.441  -1.457  -1.428  -1.232  -1.238  -1.164
330   T        -1.387  -1.393  -1.347  -1.390  -1.401  -1.316  -1.232  -1.237  -1.154
331   N        -1.387  -1.394  -1.357  -1.371  -1.386  -1.332  -1.232  -1.238  -1.164
332   V        -0.941  -0.937  -0.843  -1.049  -1.049  -0.890  -1.050  -1.043  -0.908
333   S        -0.060  -0.081  -0.070  -0.171  -0.214  -0.219  -0.292  -0.329  -0.324
334   D        -0.060  -0.081  -0.070  -0.167  -0.211  -0.225  -0.292  -0.329  -0.324
335   Q        -0.941  -0.937  -0.843  -1.210  -1.220  -1.044  -1.050  -1.043  -0.908
336   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
337   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
339   V        -1.916  -1.912  -1.788  -1.795  -1.782  -1.602  -1.505  -1.500  -1.344
340   S        -0.129  -0.122  -0.081  -0.248  -0.237  -0.170  -0.413  -0.400  -0.343
341   A         1.154   1.156   1.191   1.210   1.212   1.266   1.224   1.226   1.273
342   I        -0.858  -0.870  -0.814  -1.216  -1.231  -1.128  -0.959  -0.970  -0.875
343   P        -0.658  -0.694  -0.780  -0.465  -0.522  -0.688  -0.686  -0.732  -0.830
344   Q        -1.387  -1.365  -1.339  -1.227  -1.197  -1.153  -1.232  -1.208  -1.146
345   I         0.200   0.181   0.022   0.174   0.148  -0.091   0.132   0.104  -0.165
346   I        -0.129  -0.141  -0.083  -0.347  -0.366  -0.265  -0.413  -0.433  -0.348
347   L        -1.387  -1.394  -1.357  -1.572  -1.579  -1.500  -1.232  -1.238  -1.164
348   E        -0.858  -0.861  -0.813  -1.023  -1.022  -0.918  -0.959  -0.960  -0.875
349   M         1.154   1.156   1.191   1.409   1.411   1.456   1.224   1.226   1.273
350   R         0.200   0.193   0.020   0.365   0.355   0.044   0.132   0.121  -0.168
351   K        -1.387  -1.359  -1.354  -1.311  -1.259  -1.263  -1.232  -1.201  -1.161
352   L        -0.658  -0.694  -0.780  -0.695  -0.740  -0.813  -0.686  -0.732  -0.830
353   L         1.154   1.156   1.191   0.947   0.950   1.015   1.224   1.226   1.273
354   N        -1.387  -1.385  -1.341  -1.281  -1.282  -1.205  -1.232  -1.229  -1.148
355   L         1.154   1.156   1.191   0.947   0.950   1.015   1.224   1.226   1.273
356   I         1.154   1.156   1.191   1.071   1.074   1.133   1.224   1.226   1.273
357   S         1.154   1.156   1.191   1.169   1.171   1.227   1.224   1.226   1.273
358   F         1.154   1.156   1.191   1.285   1.289   1.338   1.224   1.226   1.273
359   F        -0.129  -0.125  -0.081  -0.066  -0.057  -0.002  -0.413  -0.405  -0.344
360   T         1.154   1.156   1.191   1.225   1.226   1.280   1.224   1.226   1.273
361   C         1.154   1.156   1.191   1.447   1.450   1.493   1.224   1.226   1.273
362   G         1.154   1.156   1.191   1.166   1.169   1.225   1.224   1.226   1.273
363   P         0.200   0.181   0.022   0.377   0.350   0.071   0.132   0.104  -0.165
364   Q        -1.916  -1.912  -1.788  -1.830  -1.824  -1.635  -1.505  -1.500  -1.344
365   E         1.154   1.156   1.191   1.105   1.109   1.166   1.224   1.226   1.273
366   V        -0.129  -0.121  -0.077  -0.228  -0.214  -0.147  -0.413  -0.399  -0.336
367   H         0.200   0.232   0.029   0.450   0.495   0.205   0.132   0.183  -0.153
368   Q         1.154   1.156   1.191   1.308   1.310   1.359   1.224   1.226   1.273
369   W         1.154   1.156   1.191   1.440   1.443   1.486   1.224   1.226   1.273
370   N        -0.858  -0.870  -0.820  -0.903  -0.921  -0.833  -0.959  -0.970  -0.882
371   I         1.154   1.156   1.191   1.071   1.074   1.133   1.224   1.226   1.273
372   R         1.154   1.156   1.191   1.305   1.308   1.357   1.224   1.226   1.273
373   E        -0.858  -0.861  -0.813  -1.023  -1.022  -0.917  -0.959  -0.960  -0.875
374   G         1.154   1.156   1.191   1.166   1.169   1.225   1.224   1.226   1.273
375   T        -0.858  -0.859  -0.822  -0.897  -0.901  -0.835  -0.959  -0.958  -0.884
376   T        -0.658  -0.641  -0.760  -0.609  -0.580  -0.814  -0.686  -0.663  -0.805
377   A         0.200   0.174   0.016   0.363   0.329   0.111   0.132   0.092  -0.176
378   Q        -0.129  -0.121  -0.077  -0.091  -0.076  -0.014  -0.413  -0.399  -0.336
379   E         1.154   1.156   1.191   1.105   1.109   1.166   1.224   1.226   1.273
380   A         1.154   1.156   1.191   1.210   1.212   1.266   1.224   1.226   1.273
381   A         1.154   1.156   1.191   1.210   1.212   1.266   1.224   1.226   1.273
382   G         1.154   1.156   1.191   1.166   1.169   1.225   1.224   1.226   1.273
383   V        -0.858  -0.841  -0.823  -1.045  -1.030  -0.962  -0.959  -0.940  -0.886
384   I         1.154   1.156   1.191   1.071   1.074   1.133   1.224   1.226   1.273
385   H         1.154   1.156   1.191   1.389   1.393   1.437   1.224   1.226   1.273
386   S        -0.129  -0.109  -0.073  -0.232  -0.195  -0.147  -0.413  -0.377  -0.330
387   D         1.154   1.156   1.191   1.197   1.198   1.254   1.224   1.226   1.273
388   L         1.154   1.156   1.191   0.947   0.950   1.015   1.224   1.226   1.273
389   R        -0.658  -0.609  -0.757  -0.435  -0.359  -0.608  -0.686  -0.621  -0.801
390   E        -0.129  -0.121  -0.077  -0.434  -0.417  -0.343  -0.413  -0.399  -0.336
391   T         1.154   1.156   1.191   1.225   1.226   1.280   1.224   1.226   1.273
392   F         1.154   1.156   1.191   1.285   1.289   1.338   1.224   1.226   1.273
393   I         1.154   1.156   1.191   1.071   1.074   1.133   1.224   1.226   1.273
394   S         0.200   0.181   0.022   0.259   0.231  -0.025   0.132   0.104  -0.165
395   A         0.200   0.181   0.022   0.303   0.276   0.018   0.132   0.104  -0.165
396   D        -1.387  -1.394  -1.357  -1.289  -1.301  -1.250  -1.232  -1.238  -1.164
397   V        -0.129  -0.122  -0.081  -0.309  -0.296  -0.241  -0.413  -0.400  -0.343
398   I        -0.129  -0.141  -0.083  -0.261  -0.275  -0.172  -0.413  -0.433  -0.348
399   K         0.200   0.193   0.020   0.125   0.116  -0.148   0.132   0.121  -0.168
400   Y        -0.858  -0.866  -0.819  -0.636  -0.644  -0.558  -0.959  -0.966  -0.881
401   D         0.200   0.193   0.020   0.275   0.264  -0.023   0.132   0.121  -0.168
402   D         0.200   0.193   0.020   0.291   0.279   0.004   0.132   0.121  -0.168
403   L         0.200   0.230   0.025   0.017   0.063  -0.255   0.132   0.179  -0.161
404   K        -0.658  -0.685  -0.768  -0.661  -0.699  -0.800  -0.686  -0.720  -0.816
405   K        -1.387  -1.412  -1.354  -1.371  -1.404  -1.293  -1.232  -1.256  -1.161
406   M        -0.858  -0.859  -0.822  -0.945  -0.960  -0.890  -0.959  -0.958  -0.884
407   E        -0.858  -0.870  -0.820  -0.956  -0.971  -0.880  -0.959  -0.970  -0.882
408   P         1.154   1.156   1.191   1.293   1.296   1.345   1.224   1.226   1.273
409   P         0.200   0.181   0.022   0.406   0.379   0.121   0.132   0.104  -0.165
410   L        -0.129  -0.141  -0.083  -0.402  -0.413  -0.303  -0.413  -0.433  -0.348
411   N        -0.858  -0.842  -0.810  -0.874  -0.855  -0.779  -0.959  -0.941  -0.872
412   E         1.154   1.156   1.191   1.105   1.109   1.166   1.224   1.226   1.273
413   S         0.200   0.174   0.016   0.273   0.236  -0.011   0.132   0.092  -0.176
414   L        -1.916  -1.912  -1.788  -1.814  -1.806  -1.620  -1.505  -1.500  -1.344
415   L         1.154   1.156   1.191   0.947   0.950   1.015   1.224   1.226   1.273
416   K         1.154   1.156   1.191   1.034   1.038   1.098   1.224   1.226   1.273
417   S        -0.658  -0.685  -0.768  -0.636  -0.680  -0.838  -0.686  -0.720  -0.816
418   K        -0.858  -0.870  -0.820  -0.925  -0.939  -0.849  -0.959  -0.970  -0.882
419   G         1.154   1.156   1.191   1.166   1.169   1.225   1.224   1.226   1.273
420   L        -0.129  -0.121  -0.077  -0.528  -0.509  -0.442  -0.413  -0.399  -0.336
421   I        -0.129  -0.141  -0.083  -0.283  -0.298  -0.196  -0.413  -0.433  -0.348
422   K        -0.658  -0.694  -0.780  -0.605  -0.650  -0.736  -0.686  -0.732  -0.830
423   R        -0.129  -0.141  -0.083  -0.238  -0.265  -0.188  -0.413  -0.433  -0.348
424   A        -1.387  -1.359  -1.354  -1.070  -1.021  -1.063  -1.232  -1.201  -1.161
425   G         1.154   1.156   1.191   1.166   1.169   1.225   1.224   1.226   1.273
426   K         1.154   1.156   1.191   1.034   1.038   1.098   1.224   1.226   1.273
427   Q        -0.658  -0.694  -0.780  -0.503  -0.563  -0.749  -0.686  -0.732  -0.830
428   Y         1.154   1.156   1.191   1.345   1.346   1.395   1.224   1.226   1.273
429   I         0.200   0.230   0.025   0.174   0.217  -0.086   0.132   0.179  -0.161
430   M        -0.129  -0.121  -0.077  -0.117  -0.106  -0.030  -0.413  -0.399  -0.336
431   Q        -0.129  -0.127  -0.084  -0.254  -0.249  -0.172  -0.413  -0.409  -0.349
432   D        -0.129  -0.136  -0.086  -0.292  -0.307  -0.234  -0.413  -0.425  -0.351
433   N        -0.129  -0.121  -0.077  -0.292  -0.278  -0.210  -0.413  -0.399  -0.336
434   D         1.154   1.156   1.191   1.197   1.198   1.254   1.224   1.226   1.273
435   I        -0.129  -0.141  -0.083  -0.347  -0.366  -0.265  -0.413  -0.433  -0.348
436   A        -1.387  -1.394  -1.357  -1.408  -1.423  -1.394  -1.232  -1.238  -1.164
437   L        -0.858  -0.841  -0.823  -1.078  -1.055  -0.963  -0.959  -0.940  -0.886
438   F        -0.129  -0.141  -0.083  -0.235  -0.260  -0.181  -0.413  -0.433  -0.348
439   K         1.154   1.156   1.191   1.034   1.038   1.098   1.224   1.226   1.273
440   A         1.154   1.156   1.191   1.210   1.212   1.266   1.224   1.226   1.273
441   A        -0.858  -0.841  -0.823  -0.883  -0.862  -0.814  -0.959  -0.940  -0.886
442   G        -0.858  -0.870  -0.820  -0.938  -0.955  -0.869  -0.959  -0.970  -0.882
443   G         0.200   0.174   0.016   0.271   0.235  -0.013   0.132   0.092  -0.176
444   K         1.154   1.156   1.191   1.034   1.038   1.098   1.224   1.226   1.273
445   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
446   K        -0.829  -0.815  -0.818  -0.866  -0.841  -0.870  -0.908  -0.889  -0.878
447   K        -0.129  -0.109  -0.073  -0.238  -0.190  -0.161  -0.413  -0.377  -0.330
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P38746
Output conservation file - output/P38746
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
