1     M         1.397   1.418   1.515   1.645   1.672   1.811   1.506   1.536   1.690
2     V        -0.605  -0.503  -0.654  -0.551  -0.433  -0.645  -0.661  -0.557  -0.696
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    D        -1.206  -1.249  -1.120  -1.236  -1.295  -1.102  -1.127  -1.152  -0.977
27    L        -0.082  -0.055  -0.154  -0.317  -0.248  -0.358  -0.228  -0.172  -0.336
28    S         0.288   0.303   0.384  -0.014   0.001   0.105  -0.055  -0.042   0.043
29    T         0.789   0.721   0.577   0.900   0.812   0.584   0.812   0.702   0.417
30    A        -1.525  -1.416  -1.412  -1.542  -1.414  -1.418  -1.268  -1.176  -1.087
31    L        -0.887  -0.907  -0.747  -1.343  -1.334  -1.078  -1.008  -1.008  -0.802
32    I        -0.082  -0.211  -0.209  -0.125  -0.339  -0.398  -0.228  -0.406  -0.423
33    H         1.397   1.418   1.515   1.534   1.560   1.707   1.506   1.536   1.690
34    G         0.288   0.361   0.409   0.020   0.137   0.197  -0.055   0.070   0.094
35    D        -0.350  -0.213  -0.595  -0.231  -0.045  -0.628  -0.315  -0.147  -0.617
36    D         1.397   1.418   1.515   1.371   1.403   1.554   1.506   1.536   1.690
37    K        -1.525  -1.548  -1.424  -1.381  -1.415  -1.231  -1.268  -1.276  -1.096
38    D        -1.895  -1.851  -1.699  -1.925  -1.859  -1.606  -1.442  -1.398  -1.192
39    N        -0.605  -0.613  -0.684  -0.469  -0.530  -0.621  -0.661  -0.695  -0.731
40    R        -0.873  -0.914  -1.050  -0.590  -0.697  -0.922  -0.748  -0.805  -0.907
41    V        -0.350  -0.537  -0.652  -0.152  -0.410  -0.587  -0.315  -0.553  -0.685
42    T        -1.895  -1.793  -1.688  -1.623  -1.470  -1.334  -1.442  -1.357  -1.185
43    D         0.789   0.721   0.577   0.830   0.745   0.519   0.812   0.702   0.417
44    V         0.789   0.847   0.595   0.861   0.936   0.594   0.812   0.896   0.450
45    A        -0.605  -0.472  -0.655  -0.605  -0.427  -0.649  -0.661  -0.499  -0.695
46    P        -0.350  -0.256  -0.585  -0.077   0.044  -0.439  -0.315  -0.200  -0.604
47    P         0.789   0.795   0.585   0.947   0.953   0.641   0.812   0.817   0.432
48    I         0.789   0.721   0.577   0.908   0.836   0.653   0.812   0.702   0.417
49    N        -0.284  -0.247  -0.218  -0.307  -0.240  -0.192  -0.575  -0.514  -0.444
50    V         0.474   0.399   0.416   0.416   0.284   0.271   0.292   0.142   0.107
51    S        -0.082   0.065  -0.143  -0.177   0.041  -0.273  -0.228  -0.020  -0.323
52    T         1.397   1.418   1.515   1.440   1.467   1.619   1.506   1.536   1.690
53    T         1.397   1.418   1.515   1.440   1.467   1.619   1.506   1.536   1.690
54    F         0.200   0.223   0.364   0.083   0.116   0.330  -0.228  -0.200   0.004
55    R        -0.605  -0.639  -0.675  -0.472  -0.505  -0.609  -0.661  -0.685  -0.715
56    Y         0.789   0.872   0.596   1.013   1.113   0.751   0.812   0.932   0.453
57    D        -1.257  -1.279  -1.121  -1.393  -1.424  -1.176  -1.181  -1.191  -0.980
58    D        -1.155  -1.205  -1.093  -1.167  -1.220  -1.053  -1.095  -1.124  -0.955
59    D        -0.605  -0.606  -0.665  -0.474  -0.455  -0.596  -0.661  -0.650  -0.707
60    -         1.397   1.418   1.515   1.473   1.501   1.650   1.506   1.536   1.690
61    -         0.288   0.347   0.402   0.084   0.186   0.246  -0.055   0.043   0.081
62    D        -0.350  -0.415  -0.619  -0.190  -0.284  -0.589  -0.315  -0.407  -0.646
63    L         1.397   1.418   1.515   1.115   1.145   1.314   1.506   1.536   1.690
64    I        -0.720  -0.817  -0.698  -0.762  -0.854  -0.680  -0.835  -0.914  -0.750
65    P         0.474   0.589   0.506   0.515   0.687   0.533   0.292   0.483   0.283
66    W        -0.873  -0.937  -1.039  -0.459  -0.570  -0.823  -0.748  -0.824  -0.897
67    T        -1.626  -1.562  -1.428  -1.571  -1.483  -1.302  -1.355  -1.293  -1.100
68    E        -1.089  -1.171  -1.097  -1.064  -1.163  -1.116  -1.008  -1.073  -0.955
69    R        -1.155  -1.079  -1.082  -1.201  -1.146  -1.046  -1.095  -1.013  -0.945
70    E        -1.089  -1.171  -1.097  -0.980  -1.097  -1.009  -1.008  -1.073  -0.955
71    N        -0.790  -0.768  -0.725  -0.851  -0.813  -0.711  -0.908  -0.879  -0.778
72    L        -0.920  -0.905  -0.765  -1.180  -1.120  -0.891  -1.030  -1.007  -0.818
73    D        -1.303  -1.191  -1.126  -1.455  -1.294  -1.175  -1.217  -1.107  -0.983
74    F        -1.303  -1.318  -1.149  -1.369  -1.391  -1.145  -1.217  -1.218  -1.002
75    M        -0.920  -0.922  -0.778  -0.937  -0.943  -0.767  -1.030  -1.024  -0.831
76    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
77    E        -1.525  -1.474  -1.410  -1.381  -1.284  -1.205  -1.268  -1.210  -1.084
78    K        -1.358  -1.261  -1.139  -1.376  -1.248  -1.045  -1.268  -1.178  -0.995
79    K        -1.626  -1.652  -1.441  -1.510  -1.535  -1.250  -1.355  -1.354  -1.109
80    P        -1.358  -1.311  -1.385  -1.096  -1.039  -1.205  -1.095  -1.049  -1.062
81    V        -0.720  -0.725  -0.690  -0.754  -0.755  -0.659  -0.835  -0.838  -0.743
82    Y         1.397   1.418   1.515   1.531   1.558   1.705   1.506   1.536   1.690
83    S         0.474   0.437   0.426   0.327   0.255   0.194   0.292   0.212   0.128
84    R         1.397   1.418   1.515   1.506   1.533   1.681   1.506   1.536   1.690
85    L        -0.887  -0.882  -0.744  -1.231  -1.178  -0.960  -1.008  -0.986  -0.799
86    A        -1.257  -1.184  -1.116  -1.369  -1.288  -1.138  -1.181  -1.114  -0.975
87    H        -0.350  -0.475  -0.635  -0.037  -0.237  -0.499  -0.315  -0.482  -0.666
88    P         0.789   0.661   0.567   0.971   0.807   0.667   0.812   0.605   0.398
89    N         0.789   0.795   0.585   0.988   1.002   0.699   0.812   0.817   0.432
90    S        -0.605  -0.674  -0.682  -0.673  -0.766  -0.799  -0.661  -0.732  -0.728
91    T        -1.525  -1.531  -1.417  -1.553  -1.565  -1.465  -1.268  -1.258  -1.090
92    R         0.789   0.794   0.584   0.997   1.005   0.729   0.812   0.815   0.431
93    L        -0.720  -0.788  -0.707  -1.002  -1.103  -0.969  -0.835  -0.893  -0.760
94    E         1.397   1.418   1.515   1.426   1.462   1.606   1.506   1.536   1.690
95    S        -0.517  -0.460  -0.301  -0.881  -0.790  -0.542  -0.835  -0.758  -0.547
96    I        -1.089  -1.051  -1.075  -1.143  -1.093  -1.193  -1.008  -0.972  -0.936
97    F        -0.082   0.014  -0.147  -0.325  -0.180  -0.389  -0.228  -0.079  -0.326
98    S        -0.605  -0.571  -0.675  -0.635  -0.576  -0.739  -0.661  -0.616  -0.719
99    E        -0.821  -0.738  -0.722  -0.952  -0.811  -0.792  -0.921  -0.814  -0.773
100   I        -0.082  -0.193  -0.210  -0.125  -0.314  -0.401  -0.228  -0.392  -0.425
101   L        -0.350  -0.280  -0.596  -0.440  -0.348  -0.758  -0.315  -0.231  -0.618
102   D        -0.821  -0.707  -0.712  -0.890  -0.695  -0.722  -0.921  -0.773  -0.761
103   G        -0.605  -0.689  -0.708  -0.555  -0.730  -0.713  -0.661  -0.783  -0.759
104   Y        -1.089  -0.942  -1.052  -0.866  -0.655  -0.816  -1.008  -0.839  -0.915
105   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
106   A        -0.605  -0.579  -0.681  -0.659  -0.649  -0.768  -0.661  -0.644  -0.727
107   V         0.789   0.721   0.577   0.825   0.732   0.476   0.812   0.702   0.417
108   I        -0.887  -0.859  -0.733  -1.074  -1.009  -0.821  -1.008  -0.961  -0.786
109   Y         1.397   1.418   1.515   1.531   1.558   1.705   1.506   1.536   1.690
110   S        -0.821  -0.780  -0.733  -0.960  -0.918  -0.821  -0.921  -0.886  -0.786
111   S         0.474   0.509   0.453   0.382   0.437   0.335   0.292   0.343   0.182
112   G         1.397   1.418   1.515   1.406   1.431   1.587   1.506   1.536   1.690
113   L         1.397   1.418   1.515   1.115   1.145   1.314   1.506   1.536   1.690
114   A        -0.082  -0.100  -0.179  -0.174  -0.197  -0.341  -0.228  -0.242  -0.378
115   A         1.397   1.418   1.515   1.318   1.341   1.504   1.506   1.536   1.690
116   F         0.206   0.123  -0.103   0.467   0.351   0.021   0.205   0.077  -0.258
117   Y        -1.257  -1.255  -1.119  -1.071  -1.069  -0.868  -1.181  -1.171  -0.980
118   A         0.474   0.399   0.416   0.344   0.205   0.210   0.292   0.142   0.107
119   A        -0.451  -0.448  -0.302  -0.818  -0.839  -0.568  -0.748  -0.747  -0.549
120   M        -0.451  -0.381  -0.276  -0.803  -0.715  -0.504  -0.748  -0.665  -0.516
121   V        -0.235  -0.327  -0.229  -0.352  -0.492  -0.352  -0.488  -0.596  -0.459
122   H        -0.235  -0.242  -0.209  -0.168  -0.154  -0.110  -0.488  -0.473  -0.427
123   Y        -0.988  -0.961  -0.785  -1.174  -1.207  -0.912  -1.095  -1.063  -0.838
124   N         1.397   1.418   1.515   1.514   1.546   1.688   1.506   1.536   1.690
125   P         1.397   1.418   1.515   1.487   1.512   1.663   1.506   1.536   1.690
126   K         0.789   0.897   0.600   0.887   1.028   0.611   0.812   0.967   0.459
127   K        -1.793  -1.678  -1.663  -1.433  -1.276  -1.280  -1.355  -1.258  -1.166
128   I        -1.257  -1.218  -1.114  -1.499  -1.429  -1.220  -1.181  -1.144  -0.975
129   F        -0.720  -0.611  -0.697  -0.720  -0.631  -0.665  -0.835  -0.737  -0.751
130   I         0.206   0.074  -0.114   0.364   0.189  -0.093   0.205   0.013  -0.274
131   G         0.789   0.661   0.567   0.892   0.729   0.600   0.812   0.605   0.398
132   Q        -0.887  -0.893  -0.753  -0.898  -0.895  -0.701  -1.008  -0.998  -0.808
133   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
134   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
135   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
136   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
137   S        -0.605  -0.532  -0.652  -0.613  -0.484  -0.706  -0.661  -0.554  -0.688
138   Y         1.397   1.418   1.515   1.531   1.558   1.705   1.506   1.536   1.690
139   H         0.789   0.661   0.567   0.994   0.820   0.651   0.812   0.605   0.398
140   G         1.397   1.418   1.515   1.406   1.431   1.587   1.506   1.536   1.690
141   V        -0.235  -0.288  -0.218  -0.127  -0.175  -0.113  -0.488  -0.530  -0.440
142   R        -0.082  -0.129  -0.174   0.080   0.021  -0.084  -0.228  -0.279  -0.369
143   A        -0.821  -0.829  -0.724  -0.944  -0.920  -0.795  -0.921  -0.911  -0.775
144   I         0.789   0.795   0.585   0.875   0.890   0.587   0.812   0.817   0.432
145   A        -0.821  -0.837  -0.745  -1.132  -1.180  -1.048  -0.921  -0.940  -0.800
146   N        -0.605  -0.700  -0.681  -0.570  -0.701  -0.692  -0.661  -0.755  -0.726
147   I         0.206   0.009  -0.128   0.326   0.055  -0.206   0.205  -0.076  -0.295
148   L        -1.525  -1.563  -1.426  -1.352  -1.365  -1.154  -1.268  -1.284  -1.097
149   T        -0.821  -0.865  -0.737  -0.880  -0.924  -0.761  -0.921  -0.959  -0.790
150   R         0.789   0.721   0.577   0.979   0.894   0.675   0.812   0.702   0.417
151   N        -0.284  -0.259  -0.231  -0.590  -0.568  -0.476  -0.575  -0.535  -0.462
152   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
153   Y        -1.525  -1.565  -1.426  -1.211  -1.261  -1.051  -1.268  -1.286  -1.097
154   G         0.474   0.509   0.453   0.460   0.508   0.403   0.292   0.343   0.182
155   I         0.789   0.880   0.599   0.584   0.697   0.347   0.812   0.943   0.458
156   E        -0.235  -0.104  -0.198  -0.331  -0.129  -0.254  -0.488  -0.315  -0.410
157   Q        -0.873  -0.971  -1.050  -0.507  -0.662  -0.836  -0.748  -0.864  -0.908
158   H        -1.257  -1.243  -1.124  -1.378  -1.413  -1.190  -1.181  -1.163  -0.982
159   P        -1.525  -1.539  -1.407  -1.460  -1.470  -1.266  -1.268  -1.270  -1.083
160   L         0.474   0.399   0.416   0.144   0.018   0.041   0.292   0.142   0.107
161   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
162   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
163   E         0.417   0.515   0.442   0.311   0.469   0.316   0.189   0.354   0.160
164   D        -0.350  -0.495  -0.640  -0.214  -0.430  -0.671  -0.315  -0.504  -0.671
165   I        -1.155  -1.207  -1.107  -1.152  -1.204  -1.044  -1.095  -1.126  -0.967
166   E        -0.605  -0.635  -0.671  -0.761  -0.759  -0.764  -0.661  -0.679  -0.711
167   K        -1.358  -1.215  -1.353  -1.142  -0.956  -1.150  -1.095  -0.955  -1.035
168   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
169   C        -1.895  -1.826  -1.696  -1.546  -1.504  -1.277  -1.442  -1.381  -1.190
170   A        -0.720  -0.766  -0.708  -1.096  -1.144  -1.016  -0.835  -0.861  -0.758
171   S        -1.257  -1.183  -1.105  -1.141  -1.039  -0.943  -1.181  -1.108  -0.965
172   E        -0.821  -0.828  -0.726  -0.901  -0.890  -0.755  -0.921  -0.920  -0.777
173   G         1.397   1.418   1.515   1.406   1.431   1.587   1.506   1.536   1.690
174   D         1.397   1.418   1.515   1.371   1.403   1.554   1.506   1.536   1.690
175   I        -0.451  -0.386  -0.277  -0.917  -0.809  -0.614  -0.748  -0.673  -0.518
176   V         0.200   0.219   0.363  -0.087  -0.061   0.167  -0.228  -0.208   0.002
177   H        -0.082  -0.106  -0.167   0.174   0.160   0.078  -0.228  -0.244  -0.356
178   L        -0.082  -0.068  -0.165  -0.363  -0.325  -0.467  -0.228  -0.193  -0.355
179   E         1.397   1.418   1.515   1.426   1.462   1.606   1.506   1.536   1.690
180   S         0.789   0.880   0.599   0.900   1.012   0.622   0.812   0.943   0.458
181   P         1.397   1.418   1.515   1.487   1.512   1.663   1.506   1.536   1.690
182   V         0.474   0.365   0.409   0.335   0.106   0.109   0.292   0.077   0.093
183   N         1.397   1.418   1.515   1.514   1.546   1.688   1.506   1.536   1.690
184   P         1.397   1.418   1.515   1.487   1.512   1.663   1.506   1.536   1.690
185   Y        -1.257  -1.234  -1.114  -1.254  -1.265  -1.068  -1.181  -1.154  -0.973
186   G         1.397   1.418   1.515   1.406   1.431   1.587   1.506   1.536   1.690
187   T        -0.350  -0.537  -0.652  -0.109  -0.376  -0.560  -0.315  -0.553  -0.685
188   S        -0.821  -0.816  -0.740  -0.999  -1.012  -0.868  -0.921  -0.920  -0.793
189   S        -1.089  -1.001  -1.072  -0.950  -0.849  -0.978  -1.008  -0.931  -0.935
190   D         1.397   1.418   1.515   1.371   1.403   1.554   1.506   1.536   1.690
191   I         0.288   0.304   0.384  -0.029  -0.014   0.055  -0.055  -0.041   0.043
192   E        -1.626  -1.631  -1.431  -1.550  -1.564  -1.270  -1.355  -1.340  -1.103
193   S        -1.089  -1.089  -1.079  -0.947  -0.918  -0.960  -1.008  -0.993  -0.938
194   L        -0.235  -0.091  -0.190  -0.247  -0.015  -0.204  -0.488  -0.284  -0.402
195   A         0.206   0.009  -0.128   0.280   0.016  -0.180   0.205  -0.076  -0.295
196   R        -0.821  -0.792  -0.737  -0.849  -0.835  -0.703  -0.921  -0.909  -0.791
197   R        -0.821  -0.863  -0.738  -0.945  -1.030  -0.865  -0.921  -0.953  -0.791
198   A         0.789   0.847   0.595   0.792   0.860   0.537   0.812   0.896   0.450
199   H         0.206   0.009  -0.128   0.476   0.205  -0.041   0.205  -0.076  -0.295
200   A        -0.988  -0.923  -0.774  -1.221  -1.101  -0.904  -1.095  -1.020  -0.827
201   K        -0.605  -0.593  -0.664  -0.530  -0.503  -0.641  -0.661  -0.628  -0.706
202   G         1.397   1.418   1.515   1.406   1.431   1.587   1.506   1.536   1.690
203   A         0.206   0.131  -0.104   0.303   0.210  -0.094   0.205   0.096  -0.260
204   L        -0.887  -0.859  -0.733  -1.153  -1.072  -0.864  -1.008  -0.961  -0.786
205   L         1.397   1.418   1.515   1.115   1.145   1.314   1.506   1.536   1.690
206   I        -1.626  -1.549  -1.431  -1.770  -1.645  -1.411  -1.355  -1.285  -1.102
207   V         0.474   0.573   0.466   0.416   0.568   0.367   0.292   0.455   0.206
208   D         1.397   1.418   1.515   1.371   1.403   1.554   1.506   1.536   1.690
209   S         0.288   0.275   0.376  -0.014  -0.056   0.089  -0.055  -0.096   0.028
210   T         1.397   1.418   1.515   1.440   1.467   1.619   1.506   1.536   1.690
211   F         1.397   1.418   1.515   1.505   1.535   1.680   1.506   1.536   1.690
212   A         1.397   1.418   1.515   1.318   1.341   1.504   1.506   1.536   1.690
213   S         0.789   0.880   0.599   0.947   1.056   0.666   0.812   0.943   0.458
214   P         1.397   1.418   1.515   1.487   1.512   1.663   1.506   1.536   1.690
215   P         1.397   1.418   1.515   1.487   1.512   1.663   1.506   1.536   1.690
216   L         0.789   0.661   0.567   0.584   0.421   0.296   0.812   0.605   0.398
217   Q         0.789   0.794   0.584   1.070   1.084   0.808   0.812   0.815   0.431
218   Y        -0.337  -0.228  -0.242  -0.407  -0.242  -0.273  -0.575  -0.422  -0.464
219   A         0.288   0.307   0.391   0.136   0.151   0.250  -0.055  -0.034   0.057
220   W        -0.235  -0.271  -0.214  -0.183  -0.239  -0.185  -0.488  -0.503  -0.432
221   N        -1.257  -1.275  -1.112  -1.227  -1.226  -0.993  -1.181  -1.174  -0.970
222   F        -0.337  -0.337  -0.264  -0.375  -0.454  -0.353  -0.575  -0.592  -0.497
223   G         1.397   1.418   1.515   1.406   1.431   1.587   1.506   1.536   1.690
224   A         0.474   0.463   0.434   0.340   0.310   0.236   0.292   0.259   0.143
225   D         1.397   1.418   1.515   1.371   1.403   1.554   1.506   1.536   1.690
226   I        -0.605  -0.597  -0.665  -0.453  -0.431  -0.527  -0.661  -0.639  -0.703
227   V         0.474   0.573   0.478   0.416   0.569   0.389   0.292   0.456   0.229
228   L        -0.720  -0.714  -0.689  -0.744  -0.692  -0.674  -0.835  -0.812  -0.740
229   Y         0.789   0.880   0.599   1.019   1.125   0.766   0.812   0.943   0.458
230   S         1.397   1.418   1.515   1.325   1.358   1.512   1.506   1.536   1.690
231   A         0.789   0.721   0.577   0.788   0.698   0.498   0.812   0.702   0.417
232   T         1.397   1.418   1.515   1.440   1.467   1.619   1.506   1.536   1.690
233   K         1.397   1.418   1.515   1.426   1.464   1.606   1.506   1.536   1.690
234   Y         0.474   0.538   0.456   0.579   0.673   0.510   0.292   0.394   0.186
235   F         0.474   0.449   0.432   0.449   0.390   0.267   0.292   0.234   0.140
236   G         0.789   0.661   0.567   0.865   0.688   0.532   0.812   0.605   0.398
237   G         1.397   1.418   1.515   1.406   1.431   1.587   1.506   1.536   1.690
238   H         1.397   1.418   1.515   1.534   1.560   1.707   1.506   1.536   1.690
239   S         1.397   1.418   1.515   1.325   1.358   1.512   1.506   1.536   1.690
240   D         1.397   1.418   1.515   1.371   1.403   1.554   1.506   1.536   1.690
241   L         0.206   0.009  -0.128   0.093  -0.159  -0.317   0.205  -0.076  -0.295
242   L         1.397   1.418   1.515   1.115   1.145   1.314   1.506   1.536   1.690
243   S        -0.082  -0.050  -0.152  -0.142  -0.064  -0.210  -0.228  -0.164  -0.334
244   G         1.397   1.418   1.515   1.406   1.431   1.587   1.506   1.536   1.690
245   V         0.474   0.478   0.441   0.416   0.418   0.321   0.292   0.286   0.158
246   L         0.789   0.661   0.567   0.589   0.426   0.307   0.812   0.605   0.398
247   V        -0.284  -0.255  -0.216  -0.591  -0.550  -0.485  -0.575  -0.528  -0.443
248   V        -0.720  -0.805  -0.705  -0.776  -0.874  -0.726  -0.835  -0.897  -0.756
249   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
250   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
251   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
252   K         0.789   0.897   0.600   0.910   1.047   0.665   0.812   0.967   0.459
253   E        -0.873  -0.888  -1.033  -0.732  -0.766  -1.016  -0.748  -0.767  -0.890
254   E        -1.895  -1.828  -1.695  -1.610  -1.487  -1.335  -1.442  -1.382  -1.190
255   A        -0.873  -0.794  -1.019  -0.662  -0.571  -0.922  -0.748  -0.672  -0.877
256   T        -1.358  -1.451  -1.399  -1.096  -1.227  -1.159  -1.095  -1.183  -1.074
257   S        -1.257  -1.301  -1.126  -1.453  -1.523  -1.292  -1.181  -1.201  -0.984
258   R        -1.793  -1.782  -1.686  -1.579  -1.626  -1.509  -1.355  -1.342  -1.183
259   Q        -1.089  -1.146  -1.085  -0.880  -0.991  -0.925  -1.008  -1.062  -0.947
260   L         1.397   1.418   1.515   1.115   1.145   1.314   1.506   1.536   1.690
261   K        -0.887  -0.850  -0.751  -1.136  -1.106  -0.927  -1.008  -0.969  -0.807
262   D        -1.895  -1.904  -1.699  -1.917  -1.960  -1.661  -1.442  -1.431  -1.192
263   D         0.789   0.721   0.577   0.844   0.764   0.553   0.812   0.702   0.417
264   R         1.397   1.418   1.515   1.506   1.533   1.681   1.506   1.536   1.690
265   I        -1.155  -1.165  -1.094  -1.427  -1.466  -1.332  -1.095  -1.092  -0.956
266   Y        -0.873  -0.758  -1.019  -0.560  -0.400  -0.837  -0.748  -0.620  -0.877
267   L         1.397   1.418   1.515   1.115   1.145   1.314   1.506   1.536   1.690
268   G         1.397   1.418   1.515   1.406   1.431   1.587   1.506   1.536   1.690
269   T        -0.082  -0.111  -0.185  -0.082  -0.120  -0.290  -0.228  -0.260  -0.387
270   N        -0.350  -0.537  -0.652  -0.063  -0.333  -0.556  -0.315  -0.553  -0.685
271   V        -0.821  -0.812  -0.734  -1.020  -1.063  -0.922  -0.921  -0.915  -0.787
272   A        -0.720  -0.750  -0.707  -0.851  -0.885  -0.787  -0.835  -0.866  -0.760
273   N         0.206   0.009  -0.128   0.458   0.194  -0.053   0.205  -0.076  -0.295
274   L         0.789   0.661   0.567   0.606   0.454   0.352   0.812   0.605   0.398
275   E         0.789   0.661   0.567   0.917   0.768   0.631   0.812   0.605   0.398
276   S        -0.082  -0.193  -0.210  -0.183  -0.364  -0.410  -0.228  -0.392  -0.425
277   F        -1.089  -0.989  -1.064  -0.792  -0.677  -0.758  -1.008  -0.920  -0.927
278   M         0.789   0.880   0.599   0.617   0.723   0.423   0.812   0.943   0.458
279   L         0.789   0.721   0.577   0.584   0.500   0.312   0.812   0.702   0.417
280   L        -0.350  -0.365  -0.611  -0.420  -0.441  -0.739  -0.315  -0.339  -0.636
281   R         1.397   1.418   1.515   1.506   1.533   1.681   1.506   1.536   1.690
282   S         1.397   1.418   1.515   1.325   1.358   1.512   1.506   1.536   1.690
283   L         1.397   1.418   1.515   1.115   1.145   1.314   1.506   1.536   1.690
284   R         1.397   1.418   1.515   1.506   1.533   1.681   1.506   1.536   1.690
285   T         1.397   1.418   1.515   1.440   1.467   1.619   1.506   1.536   1.690
286   Y         0.288   0.352   0.398   0.248   0.354   0.393  -0.055   0.053   0.072
287   E         0.206   0.076  -0.114   0.397   0.231  -0.046   0.205   0.015  -0.275
288   M         0.288   0.384   0.427  -0.048   0.088   0.184  -0.055   0.113   0.130
289   R         1.397   1.418   1.515   1.506   1.533   1.681   1.506   1.536   1.690
290   I         1.397   1.418   1.515   1.407   1.440   1.588   1.506   1.536   1.690
291   T        -1.626  -1.607  -1.430  -1.704  -1.656  -1.386  -1.355  -1.322  -1.101
292   K        -0.720  -0.681  -0.691  -0.670  -0.612  -0.586  -0.835  -0.792  -0.744
293   Q         0.789   0.661   0.567   1.056   0.900   0.747   0.812   0.605   0.398
294   S         0.288   0.328   0.401  -0.014   0.051   0.142  -0.055   0.007   0.078
295   E        -0.350  -0.279  -0.598  -0.140  -0.049  -0.517  -0.315  -0.230  -0.620
296   N         0.206   0.129  -0.104   0.452   0.352  -0.026   0.205   0.094  -0.260
297   A        -0.350  -0.306  -0.599  -0.252  -0.219  -0.620  -0.315  -0.278  -0.621
298   T        -0.720  -0.822  -0.719  -0.694  -0.800  -0.637  -0.835  -0.922  -0.771
299   K        -0.350  -0.479  -0.638  -0.192  -0.397  -0.692  -0.315  -0.482  -0.668
300   L        -0.235  -0.309  -0.223  -0.623  -0.708  -0.551  -0.488  -0.565  -0.450
301   V        -0.350  -0.414  -0.620  -0.192  -0.298  -0.616  -0.315  -0.406  -0.647
302   R        -1.358  -1.353  -1.389  -1.103  -1.099  -1.180  -1.095  -1.097  -1.065
303   F        -0.887  -0.871  -0.740  -0.765  -0.723  -0.527  -1.008  -0.976  -0.796
304   L         0.206   0.198  -0.094   0.073   0.067  -0.313   0.205   0.191  -0.245
305   S        -1.089  -1.125  -1.081  -1.078  -1.120  -1.080  -1.008  -1.037  -0.943
306   D        -0.887  -0.818  -0.741  -1.051  -0.948  -0.824  -1.008  -0.942  -0.797
307   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
308   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
309   H        -0.720  -0.827  -0.711  -0.613  -0.749  -0.588  -0.835  -0.928  -0.764
310   Q        -1.155  -1.156  -1.085  -1.112  -1.127  -1.025  -1.095  -1.083  -0.948
311   S        -0.887  -0.912  -0.751  -1.123  -1.149  -0.903  -1.008  -1.020  -0.806
312   E        -1.089  -1.046  -1.064  -1.005  -0.928  -0.974  -1.008  -0.968  -0.926
313   F        -0.235  -0.212  -0.201  -0.205  -0.137  -0.140  -0.488  -0.422  -0.414
314   D        -1.358  -1.353  -1.389  -1.129  -1.162  -1.264  -1.095  -1.097  -1.065
315   K        -1.358  -1.470  -1.408  -1.185  -1.380  -1.341  -1.095  -1.199  -1.082
316   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
317   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
318   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
319   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
320   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
321   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
322   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
323   V        -0.259  -0.368  -0.270  -0.398  -0.621  -0.495  -0.460  -0.627  -0.503
324   L         0.206   0.009  -0.128   0.055  -0.208  -0.406   0.205  -0.076  -0.295
325   K        -1.089  -1.146  -1.085  -1.037  -1.160  -1.068  -1.008  -1.062  -0.947
326   T        -1.895  -1.880  -1.697  -1.585  -1.562  -1.287  -1.442  -1.417  -1.191
327   I         0.200   0.222   0.364  -0.084  -0.053   0.168  -0.228  -0.203   0.003
328   Y        -1.089  -1.045  -1.057  -0.830  -0.749  -0.790  -1.008  -0.950  -0.919
329   H         1.397   1.418   1.515   1.534   1.560   1.707   1.506   1.536   1.690
330   S        -0.350  -0.538  -0.650  -0.244  -0.508  -0.695  -0.315  -0.554  -0.683
331   S         1.397   1.418   1.515   1.325   1.358   1.512   1.506   1.536   1.690
332   L         0.206   0.131  -0.104   0.099   0.012  -0.271   0.205   0.096  -0.260
333   Q         1.397   1.418   1.515   1.570   1.604   1.741   1.506   1.536   1.690
334   T        -0.082  -0.099  -0.182  -0.041  -0.050  -0.210  -0.228  -0.241  -0.382
335   E         0.206   0.074  -0.114   0.369   0.199  -0.108   0.205   0.013  -0.274
336   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
337   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
339   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
340   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
341   E        -1.257  -1.165  -1.100  -1.319  -1.181  -1.096  -1.181  -1.089  -0.963
342   F         0.206   0.129  -0.104   0.504   0.416   0.101   0.205   0.094  -0.260
343   V         0.206   0.129  -0.104   0.295   0.184  -0.210   0.205   0.094  -0.260
344   K         0.206   0.009  -0.128   0.373   0.110  -0.123   0.205  -0.076  -0.295
345   K         0.789   0.847   0.595   0.899   0.982   0.632   0.812   0.896   0.450
346   Q         0.789   0.661   0.567   1.053   0.897   0.741   0.812   0.605   0.398
347   L         0.474   0.434   0.430   0.217   0.161   0.188   0.292   0.207   0.136
348   V        -1.525  -1.456  -1.403  -1.403  -1.305  -1.249  -1.268  -1.204  -1.080
349   G        -0.082   0.009  -0.148  -0.041   0.097  -0.140  -0.228  -0.087  -0.327
350   G         1.397   1.418   1.515   1.406   1.431   1.587   1.506   1.536   1.690
351   Y        -0.350  -0.538  -0.650   0.019  -0.236  -0.405  -0.315  -0.554  -0.683
352   G        -0.720  -0.708  -0.698  -0.850  -0.838  -0.794  -0.835  -0.814  -0.749
353   P         0.789   0.661   0.567   0.947   0.772   0.609   0.812   0.605   0.398
354   V         0.789   0.661   0.567   0.895   0.747   0.632   0.812   0.605   0.398
355   F         1.397   1.418   1.515   1.505   1.535   1.680   1.506   1.536   1.690
356   A        -0.821  -0.708  -0.696  -0.898  -0.728  -0.711  -0.921  -0.773  -0.741
357   I        -0.082  -0.133  -0.201  -0.125  -0.220  -0.383  -0.228  -0.317  -0.413
358   T        -0.720  -0.812  -0.713  -0.782  -0.912  -0.774  -0.835  -0.908  -0.764
359   L         0.789   0.795   0.585   0.617   0.630   0.403   0.812   0.817   0.432
360   Y        -2.163  -1.997  -1.916  -1.767  -1.544  -1.429  -1.528  -1.400  -1.250
361   T        -0.082   0.101  -0.144  -0.112   0.149  -0.194  -0.228   0.035  -0.327
362   K        -0.720  -0.766  -0.708  -0.745  -0.783  -0.695  -0.835  -0.861  -0.758
363   E        -1.358  -1.393  -1.399  -1.144  -1.197  -1.261  -1.095  -1.133  -1.074
364   Q        -1.358  -1.348  -1.387  -1.053  -1.056  -1.204  -1.095  -1.089  -1.064
365   C         0.288   0.384   0.427   0.148   0.284   0.364  -0.055   0.113   0.130
366   K         0.474   0.509   0.453   0.479   0.536   0.418   0.292   0.343   0.182
367   Q        -1.525  -1.518  -1.417  -1.247  -1.251  -1.126  -1.268  -1.259  -1.091
368   L         0.288   0.380   0.417  -0.119   0.026   0.096  -0.055   0.106   0.110
369   P         0.789   0.661   0.567   0.991   0.836   0.718   0.812   0.605   0.398
370   L        -0.605  -0.593  -0.670  -0.666  -0.593  -0.709  -0.661  -0.634  -0.709
371   K         0.206   0.123  -0.103   0.334   0.229  -0.170   0.205   0.077  -0.258
372   L         1.397   1.418   1.515   1.115   1.145   1.314   1.506   1.536   1.690
373   K        -0.605  -0.551  -0.650  -0.478  -0.381  -0.530  -0.661  -0.582  -0.685
374   Y        -0.605  -0.608  -0.687  -0.483  -0.533  -0.632  -0.661  -0.679  -0.734
375   F         1.397   1.418   1.515   1.505   1.535   1.680   1.506   1.536   1.690
376   H         0.206   0.248  -0.081   0.516   0.568   0.126   0.205   0.260  -0.225
377   H         1.397   1.418   1.515   1.534   1.560   1.707   1.506   1.536   1.690
378   A         1.397   1.418   1.515   1.318   1.341   1.504   1.506   1.536   1.690
379   T         1.397   1.418   1.515   1.440   1.467   1.619   1.506   1.536   1.690
380   S         1.397   1.418   1.515   1.325   1.358   1.512   1.506   1.536   1.690
381   L         1.397   1.418   1.515   1.115   1.145   1.314   1.506   1.536   1.690
382   G         1.397   1.418   1.515   1.406   1.431   1.587   1.506   1.536   1.690
383   G         0.789   0.661   0.567   0.866   0.691   0.535   0.812   0.605   0.398
384   I         0.206   0.276  -0.074   0.341   0.432  -0.059   0.205   0.298  -0.216
385   E         1.397   1.418   1.515   1.426   1.462   1.606   1.506   1.536   1.690
386   S         1.397   1.418   1.515   1.325   1.358   1.512   1.506   1.536   1.690
387   L         1.397   1.418   1.515   1.115   1.145   1.314   1.506   1.536   1.690
388   V         0.474   0.562   0.483   0.427   0.566   0.406   0.292   0.436   0.239
389   E         1.397   1.418   1.515   1.426   1.462   1.606   1.506   1.536   1.690
390   W         1.397   1.418   1.515   1.669   1.696   1.834   1.506   1.536   1.690
391   R         1.397   1.418   1.515   1.506   1.533   1.681   1.506   1.536   1.690
392   A        -0.605  -0.638  -0.673  -0.692  -0.723  -0.819  -0.661  -0.683  -0.712
393   M         0.288   0.380   0.417   0.196   0.383   0.350  -0.055   0.106   0.110
394   T         0.200   0.229   0.367  -0.118  -0.073   0.148  -0.228  -0.188   0.010
395   D         1.397   1.418   1.515   1.371   1.403   1.554   1.506   1.536   1.690
396   P        -1.155  -1.179  -1.105  -1.262  -1.324  -1.234  -1.095  -1.100  -0.965
397   Y        -1.155  -1.241  -1.110  -1.024  -1.142  -0.948  -1.095  -1.154  -0.970
398   I        -0.082   0.010  -0.145  -0.074   0.080  -0.172  -0.228  -0.085  -0.323
399   D        -0.720  -0.655  -0.689  -0.844  -0.731  -0.749  -0.835  -0.751  -0.739
400   Q        -0.337  -0.284  -0.248  -0.321  -0.256  -0.220  -0.575  -0.510  -0.472
401   T        -0.605  -0.689  -0.708  -0.509  -0.659  -0.689  -0.661  -0.783  -0.759
402   L         0.789   0.795   0.585   0.601   0.613   0.366   0.812   0.817   0.432
403   I        -0.235  -0.271  -0.214  -0.623  -0.648  -0.542  -0.488  -0.503  -0.432
404   R         1.397   1.418   1.515   1.506   1.533   1.681   1.506   1.536   1.690
405   V        -0.605  -0.622  -0.681  -0.670  -0.742  -0.827  -0.661  -0.698  -0.728
406   S         1.397   1.418   1.515   1.325   1.358   1.512   1.506   1.536   1.690
407   V         0.288   0.282   0.376   0.088   0.067   0.192  -0.055  -0.082   0.028
408   G         1.397   1.418   1.515   1.406   1.431   1.587   1.506   1.536   1.690
409   C        -1.089  -1.055  -1.062  -1.004  -0.969  -1.015  -1.008  -0.962  -0.921
410   E         1.397   1.418   1.515   1.426   1.462   1.606   1.506   1.536   1.690
411   S        -0.517  -0.470  -0.306  -0.792  -0.723  -0.472  -0.835  -0.773  -0.554
412   A        -0.873  -0.854  -1.019  -0.694  -0.666  -0.885  -0.748  -0.729  -0.877
413   N        -0.605  -0.681  -0.684  -0.555  -0.667  -0.670  -0.661  -0.743  -0.729
414   D         1.397   1.418   1.515   1.371   1.403   1.554   1.506   1.536   1.690
415   L         1.397   1.418   1.515   1.115   1.145   1.314   1.506   1.536   1.690
416   I         0.206   0.129  -0.104   0.326   0.230  -0.163   0.205   0.094  -0.260
417   K        -0.605  -0.612  -0.667  -0.649  -0.651  -0.743  -0.661  -0.655  -0.708
418   D         1.397   1.418   1.515   1.371   1.403   1.554   1.506   1.536   1.690
419   L        -0.235  -0.133  -0.204  -0.566  -0.427  -0.468  -0.488  -0.352  -0.423
420   A        -1.525  -1.597  -1.426  -1.501  -1.584  -1.345  -1.268  -1.311  -1.098
421   S        -1.793  -1.692  -1.661  -1.419  -1.265  -1.283  -1.355  -1.270  -1.165
422   A        -0.235  -0.329  -0.230  -0.441  -0.577  -0.411  -0.488  -0.598  -0.460
423   L         0.474   0.449   0.427   0.174   0.134   0.110   0.292   0.235   0.129
424   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
425   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
426   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
427   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
428   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
429   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
430   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
431   K        -1.089  -1.071  -1.074  -1.001  -1.013  -0.995  -1.008  -1.005  -0.937
432   E        -1.257  -1.197  -1.118  -1.349  -1.268  -1.111  -1.181  -1.117  -0.977
433   L        -0.172  -0.143  -0.203  -0.514  -0.476  -0.549  -0.359  -0.323  -0.413
434   Q        -1.320  -1.310  -1.132  -1.330  -1.323  -1.075  -1.237  -1.213  -0.989
435   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
436   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
437   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
438   D        -0.924  -0.871  -0.757  -0.998  -0.914  -0.763  -1.022  -0.961  -0.807
439   A         0.224   0.261   0.374  -0.258  -0.198  -0.036  -0.179  -0.124   0.024
440   A        -0.924  -0.871  -0.757  -0.960  -0.878  -0.745  -1.022  -0.961  -0.807
441   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P38716
Output conservation file - output/P38716
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
