1     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     M         0.805   0.815   0.851   1.041   1.047   1.075   0.838   0.850   0.901
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    S        -0.917  -1.096  -1.207  -0.818  -1.083  -1.291  -0.885  -1.107  -1.232
12    T        -1.529  -1.524  -1.255  -1.582  -1.578  -1.179  -1.668  -1.650  -1.289
13    N         0.805   0.815   0.851   0.876   0.886   0.937   0.838   0.850   0.901
14    S        -0.082  -0.067  -0.402  -0.057  -0.035  -0.579  -0.102  -0.080  -0.613
15    I         0.805   0.815   0.851   0.646   0.664   0.745   0.838   0.850   0.901
16    K         0.805   0.815   0.851   0.813   0.826   0.884   0.838   0.850   0.901
17    L        -0.082  -0.232  -0.412  -0.218  -0.414  -0.708  -0.102  -0.322  -0.631
18    L        -0.917  -1.096  -1.207  -0.940  -1.160  -1.305  -0.885  -1.107  -1.232
19    A        -0.082  -0.067  -0.402  -0.148  -0.129  -0.525  -0.102  -0.080  -0.613
20    G         0.805   0.815   0.851   0.855   0.869   0.919   0.838   0.850   0.901
21    N         0.805   0.815   0.851   0.876   0.886   0.937   0.838   0.850   0.901
22    S         0.805   0.815   0.851   0.757   0.772   0.837   0.838   0.850   0.901
23    H         0.805   0.815   0.851   1.000   1.013   1.041   0.838   0.850   0.901
24    P         0.805   0.815   0.851   0.977   0.988   1.022   0.838   0.850   0.901
25    G        -0.917  -0.826  -1.190  -0.696  -0.584  -1.172  -0.885  -0.770  -1.211
26    L         0.805   0.815   0.851   0.589   0.615   0.696   0.838   0.850   0.901
27    A        -0.917  -0.989  -1.199  -0.849  -0.934  -1.123  -0.885  -0.970  -1.223
28    E        -1.262  -1.166  -1.222  -1.164  -1.051  -1.098  -1.355  -1.245  -1.252
29    L        -1.690  -1.750  -1.774  -1.679  -1.767  -1.756  -1.511  -1.574  -1.533
30    I        -1.262  -1.195  -1.230  -1.520  -1.455  -1.471  -1.355  -1.304  -1.261
31    S        -0.672  -0.660  -0.478  -1.079  -1.076  -0.753  -1.041  -1.023  -0.742
32    Q        -1.957  -1.935  -1.784  -1.719  -1.686  -1.485  -1.825  -1.779  -1.544
33    R        -0.917  -0.800  -1.188  -0.640  -0.493  -1.077  -0.885  -0.734  -1.209
34    L        -0.082  -0.232  -0.412  -0.218  -0.414  -0.708  -0.102  -0.322  -0.631
35    G        -0.082  -0.131  -0.405   0.067   0.006  -0.443  -0.102  -0.171  -0.618
36    V        -1.529  -1.437  -1.247  -1.998  -1.829  -1.515  -1.668  -1.542  -1.281
37    P        -1.957  -1.888  -1.789  -1.759  -1.708  -1.543  -1.825  -1.753  -1.548
38    L        -0.082  -0.131  -0.405  -0.218  -0.269  -0.694  -0.102  -0.171  -0.618
39    S        -1.262  -1.375  -1.237  -1.404  -1.576  -1.355  -1.355  -1.474  -1.269
40    K        -0.489  -0.437  -0.458  -0.540  -0.458  -0.514  -0.728  -0.644  -0.708
41    V        -0.672  -0.646  -0.477  -1.089  -1.046  -0.750  -1.041  -0.997  -0.741
42    G        -0.082  -0.232  -0.412   0.042  -0.173  -0.526  -0.102  -0.322  -0.631
43    V        -0.489  -0.500  -0.458  -0.746  -0.779  -0.734  -0.728  -0.749  -0.709
44    Y        -1.367  -1.405  -1.234  -1.165  -1.216  -1.019  -1.511  -1.516  -1.265
45    Q         0.805   0.815   0.851   0.988   0.998   1.030   0.838   0.850   0.901
46    Y        -0.082  -0.108  -0.406   0.308   0.277  -0.187  -0.102  -0.139  -0.620
47    S        -0.489  -0.500  -0.458  -0.603  -0.619  -0.567  -0.728  -0.749  -0.709
48    N         0.805   0.815   0.851   0.876   0.886   0.937   0.838   0.850   0.901
49    K        -2.547  -2.505  -2.222  -2.331  -2.273  -1.902  -2.138  -2.079  -1.719
50    E         0.805   0.815   0.851   0.879   0.890   0.939   0.838   0.850   0.901
51    T         0.805   0.815   0.851   0.850   0.870   0.915   0.838   0.850   0.901
52    S        -0.489  -0.500  -0.458  -0.699  -0.729  -0.699  -0.728  -0.749  -0.709
53    V         0.805   0.815   0.851   0.709   0.720   0.797   0.838   0.850   0.901
54    T        -0.489  -0.500  -0.458  -0.610  -0.635  -0.633  -0.728  -0.749  -0.709
55    I        -0.489  -0.500  -0.458  -0.764  -0.785  -0.719  -0.728  -0.749  -0.709
56    G         0.805   0.815   0.851   0.855   0.869   0.919   0.838   0.850   0.901
57    E         0.805   0.815   0.851   0.879   0.890   0.939   0.838   0.850   0.901
58    S         0.805   0.815   0.851   0.757   0.772   0.837   0.838   0.850   0.901
59    I        -0.672  -0.557  -0.456  -1.089  -0.863  -0.703  -1.041  -0.843  -0.705
60    R         0.805   0.815   0.851   0.894   0.899   0.952   0.838   0.850   0.901
61    D         0.805   0.815   0.851   0.786   0.802   0.862   0.838   0.850   0.901
62    E         0.805   0.815   0.851   0.879   0.890   0.939   0.838   0.850   0.901
63    D         0.805   0.815   0.851   0.786   0.802   0.862   0.838   0.850   0.901
64    V         0.805   0.815   0.851   0.709   0.720   0.797   0.838   0.850   0.901
65    Y        -0.489  -0.565  -0.469  -0.259  -0.390  -0.295  -0.728  -0.857  -0.726
66    I        -0.082  -0.108  -0.406  -0.150  -0.179  -0.624  -0.102  -0.139  -0.620
67    I        -0.489  -0.565  -0.469  -0.810  -0.955  -0.806  -0.728  -0.857  -0.726
68    Q         0.805   0.815   0.851   0.988   0.998   1.030   0.838   0.850   0.901
69    T         0.805   0.815   0.851   0.850   0.870   0.915   0.838   0.850   0.901
70    G         0.805   0.815   0.851   0.855   0.869   0.919   0.838   0.850   0.901
71    Y        -1.690  -1.361  -1.759  -1.215  -0.774  -1.414  -1.511  -1.139  -1.520
72    G         0.805   0.815   0.851   0.855   0.869   0.919   0.838   0.850   0.901
73    E        -0.277  -0.146  -0.439  -0.221  -0.031  -0.564  -0.390  -0.193  -0.676
74    H        -2.076  -2.073  -1.805  -1.809  -1.833  -1.465  -1.925  -1.906  -1.562
75    E        -0.917  -1.096  -1.207  -0.639  -0.891  -1.085  -0.885  -1.107  -1.232
76    I        -0.489  -0.420  -0.455  -0.764  -0.646  -0.713  -0.728  -0.616  -0.703
77    N         0.805   0.815   0.851   0.876   0.886   0.937   0.838   0.850   0.901
78    D         0.805   0.815   0.851   0.786   0.802   0.862   0.838   0.850   0.901
79    F        -0.082  -0.232  -0.412   0.276   0.081  -0.229  -0.102  -0.322  -0.631
80    L         0.805   0.815   0.851   0.589   0.615   0.696   0.838   0.850   0.901
81    M         0.805   0.815   0.851   1.041   1.047   1.075   0.838   0.850   0.901
82    E         0.805   0.815   0.851   0.879   0.890   0.939   0.838   0.850   0.901
83    L         0.805   0.815   0.851   0.589   0.615   0.696   0.838   0.850   0.901
84    L         0.805   0.815   0.851   0.589   0.615   0.696   0.838   0.850   0.901
85    I        -0.082  -0.131  -0.405  -0.092  -0.143  -0.475  -0.102  -0.171  -0.618
86    L        -1.262  -1.251  -1.215  -1.466  -1.371  -1.303  -1.355  -1.305  -1.242
87    I         0.805   0.815   0.851   0.646   0.664   0.745   0.838   0.850   0.901
88    H        -0.672  -0.663  -0.478  -0.706  -0.710  -0.434  -1.041  -1.028  -0.742
89    A         0.805   0.815   0.851   0.597   0.608   0.703   0.838   0.850   0.901
90    C         0.805   0.815   0.851   1.044   1.049   1.077   0.838   0.850   0.901
91    K        -0.672  -0.660  -0.478  -0.848  -0.832  -0.534  -1.041  -1.023  -0.742
92    T        -0.917  -1.096  -1.207  -0.722  -0.978  -1.220  -0.885  -1.107  -1.232
93    A         0.805   0.815   0.851   0.597   0.608   0.703   0.838   0.850   0.901
94    S         0.805   0.815   0.851   0.757   0.772   0.837   0.838   0.850   0.901
95    V        -0.489  -0.323  -0.425  -0.812  -0.544  -0.696  -0.728  -0.461  -0.653
96    R         0.805   0.815   0.851   0.894   0.899   0.952   0.838   0.850   0.901
97    R         0.805   0.815   0.851   0.894   0.899   0.952   0.838   0.850   0.901
98    I         0.805   0.815   0.851   0.646   0.664   0.745   0.838   0.850   0.901
99    T         0.805   0.815   0.851   0.850   0.870   0.915   0.838   0.850   0.901
100   A         0.805   0.815   0.851   0.597   0.608   0.703   0.838   0.850   0.901
101   V        -0.082  -0.232  -0.412  -0.097  -0.309  -0.616  -0.102  -0.322  -0.631
102   I         0.805   0.815   0.851   0.646   0.664   0.745   0.838   0.850   0.901
103   P         0.805   0.815   0.851   0.977   0.988   1.022   0.838   0.850   0.901
104   N        -0.917  -1.096  -1.207  -0.630  -0.869  -1.063  -0.885  -1.107  -1.232
105   F         0.805   0.815   0.851   1.026   1.034   1.062   0.838   0.850   0.901
106   P         0.805   0.815   0.851   0.977   0.988   1.022   0.838   0.850   0.901
107   Y         0.805   0.815   0.851   1.054   1.065   1.086   0.838   0.850   0.901
108   A         0.805   0.815   0.851   0.597   0.608   0.703   0.838   0.850   0.901
109   R         0.805   0.815   0.851   0.894   0.899   0.952   0.838   0.850   0.901
110   Q         0.805   0.815   0.851   0.988   0.998   1.030   0.838   0.850   0.901
111   D         0.805   0.815   0.851   0.786   0.802   0.862   0.838   0.850   0.901
112   K         0.805   0.815   0.851   0.813   0.826   0.884   0.838   0.850   0.901
113   K         0.805   0.815   0.851   0.813   0.826   0.884   0.838   0.850   0.901
114   D         0.805   0.815   0.851   0.786   0.802   0.862   0.838   0.850   0.901
115   K         0.805   0.815   0.851   0.813   0.826   0.884   0.838   0.850   0.901
116   S         0.805   0.815   0.851   0.757   0.772   0.837   0.838   0.850   0.901
117   R         0.805   0.815   0.851   0.894   0.899   0.952   0.838   0.850   0.901
118   A         0.805   0.815   0.851   0.597   0.608   0.703   0.838   0.850   0.901
119   P         0.805   0.815   0.851   0.977   0.988   1.022   0.838   0.850   0.901
120   I         0.805   0.815   0.851   0.646   0.664   0.745   0.838   0.850   0.901
121   T         0.805   0.815   0.851   0.850   0.870   0.915   0.838   0.850   0.901
122   A         0.805   0.815   0.851   0.597   0.608   0.703   0.838   0.850   0.901
123   K        -0.082  -0.232  -0.412   0.048  -0.148  -0.429  -0.102  -0.322  -0.631
124   L         0.805   0.815   0.851   0.589   0.615   0.696   0.838   0.850   0.901
125   I        -1.367  -1.342  -1.228  -1.602  -1.533  -1.271  -1.511  -1.456  -1.259
126   A         0.805   0.815   0.851   0.597   0.608   0.703   0.838   0.850   0.901
127   N        -0.917  -0.667  -1.181  -0.631  -0.320  -1.024  -0.885  -0.570  -1.200
128   L        -0.672  -0.637  -0.476  -0.842  -0.777  -0.561  -1.041  -0.983  -0.739
129   L        -0.082  -0.131  -0.405  -0.218  -0.269  -0.694  -0.102  -0.171  -0.618
130   E        -0.672  -0.557  -0.456  -0.715  -0.502  -0.390  -1.041  -0.843  -0.705
131   T         0.805   0.815   0.851   0.850   0.870   0.915   0.838   0.850   0.901
132   A         0.805   0.815   0.851   0.597   0.608   0.703   0.838   0.850   0.901
133   G         0.805   0.815   0.851   0.855   0.869   0.919   0.838   0.850   0.901
134   C         0.805   0.815   0.851   1.044   1.049   1.077   0.838   0.850   0.901
135   D        -0.489  -0.550  -0.469  -0.565  -0.668  -0.550  -0.728  -0.831  -0.727
136   H         0.805   0.815   0.851   1.000   1.013   1.041   0.838   0.850   0.901
137   V        -0.082  -0.232  -0.412  -0.097  -0.309  -0.616  -0.102  -0.322  -0.631
138   I         0.805   0.815   0.851   0.646   0.664   0.745   0.838   0.850   0.901
139   T         0.805   0.815   0.851   0.850   0.870   0.915   0.838   0.850   0.901
140   M        -0.082  -0.067  -0.402   0.226   0.242  -0.365  -0.102  -0.080  -0.613
141   D         0.805   0.815   0.851   0.786   0.802   0.862   0.838   0.850   0.901
142   L         0.805   0.815   0.851   0.589   0.615   0.696   0.838   0.850   0.901
143   H         0.805   0.815   0.851   1.000   1.013   1.041   0.838   0.850   0.901
144   A         0.805   0.815   0.851   0.597   0.608   0.703   0.838   0.850   0.901
145   S         0.805   0.815   0.851   0.757   0.772   0.837   0.838   0.850   0.901
146   Q         0.805   0.815   0.851   0.988   0.998   1.030   0.838   0.850   0.901
147   I         0.805   0.815   0.851   0.646   0.664   0.745   0.838   0.850   0.901
148   Q         0.805   0.815   0.851   0.988   0.998   1.030   0.838   0.850   0.901
149   G         0.805   0.815   0.851   0.855   0.869   0.919   0.838   0.850   0.901
150   F         0.805   0.815   0.851   1.026   1.034   1.062   0.838   0.850   0.901
151   F         0.805   0.815   0.851   1.026   1.034   1.062   0.838   0.850   0.901
152   H        -1.529  -1.524  -1.255  -1.457  -1.474  -1.090  -1.668  -1.650  -1.289
153   I        -0.672  -0.557  -0.456  -1.089  -0.863  -0.703  -1.041  -0.843  -0.705
154   P         0.805   0.815   0.851   0.977   0.988   1.022   0.838   0.850   0.901
155   V         0.805   0.815   0.851   0.709   0.720   0.797   0.838   0.850   0.901
156   D         0.805   0.815   0.851   0.786   0.802   0.862   0.838   0.850   0.901
157   N         0.805   0.815   0.851   0.876   0.886   0.937   0.838   0.850   0.901
158   L         0.805   0.815   0.851   0.589   0.615   0.696   0.838   0.850   0.901
159   Y         0.805   0.815   0.851   1.054   1.065   1.086   0.838   0.850   0.901
160   G        -0.917  -0.826  -1.190  -0.945  -0.831  -1.304  -0.885  -0.770  -1.211
161   E         0.805   0.815   0.851   0.879   0.890   0.939   0.838   0.850   0.901
162   P         0.805   0.815   0.851   0.977   0.988   1.022   0.838   0.850   0.901
163   S         0.805   0.815   0.851   0.757   0.772   0.837   0.838   0.850   0.901
164   V        -0.082  -0.108  -0.406  -0.063  -0.094  -0.514  -0.102  -0.139  -0.620
165   L         0.805   0.815   0.851   0.589   0.615   0.696   0.838   0.850   0.901
166   N        -1.262  -1.028  -1.210  -1.162  -0.816  -1.103  -1.355  -1.043  -1.236
167   Y        -0.082  -0.067  -0.402   0.304   0.323  -0.191  -0.102  -0.080  -0.613
168   I         0.805   0.815   0.851   0.646   0.664   0.745   0.838   0.850   0.901
169   R        -1.262  -1.175  -1.226  -1.150  -1.059  -1.090  -1.355  -1.259  -1.256
170   T        -1.957  -1.767  -1.776  -1.780  -1.490  -1.510  -1.825  -1.600  -1.536
171   K        -1.367  -1.324  -1.232  -1.371  -1.272  -1.105  -1.511  -1.430  -1.263
172   T        -1.957  -2.036  -1.799  -1.807  -1.923  -1.632  -1.825  -1.876  -1.557
173   D        -0.917  -0.953  -1.204  -0.745  -0.790  -1.173  -0.885  -0.925  -1.228
174   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
175   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
176   F        -2.975  -2.781  -2.576  -2.801  -2.505  -2.231  -2.294  -2.122  -1.833
177   N        -2.547  -2.388  -2.216  -2.374  -2.165  -1.898  -2.138  -1.990  -1.715
178   N        -1.957  -2.036  -1.799  -1.830  -1.935  -1.598  -1.825  -1.876  -1.557
179   A        -1.957  -1.966  -1.787  -2.175  -2.176  -1.904  -1.825  -1.813  -1.547
180   I        -0.489  -0.565  -0.469  -0.764  -0.903  -0.738  -0.728  -0.857  -0.726
181   L        -1.367  -1.340  -1.229  -1.692  -1.590  -1.331  -1.511  -1.446  -1.259
182   V         0.805   0.815   0.851   0.709   0.720   0.797   0.838   0.850   0.901
183   S         0.805   0.815   0.851   0.757   0.772   0.837   0.838   0.850   0.901
184   P         0.805   0.815   0.851   0.977   0.988   1.022   0.838   0.850   0.901
185   D         0.805   0.815   0.851   0.786   0.802   0.862   0.838   0.850   0.901
186   A         0.805   0.815   0.851   0.597   0.608   0.703   0.838   0.850   0.901
187   G         0.805   0.815   0.851   0.855   0.869   0.919   0.838   0.850   0.901
188   G         0.805   0.815   0.851   0.855   0.869   0.919   0.838   0.850   0.901
189   A         0.805   0.815   0.851   0.597   0.608   0.703   0.838   0.850   0.901
190   K         0.805   0.815   0.851   0.813   0.826   0.884   0.838   0.850   0.901
191   R         0.805   0.815   0.851   0.894   0.899   0.952   0.838   0.850   0.901
192   V        -0.489  -0.565  -0.469  -0.746  -0.906  -0.758  -0.728  -0.857  -0.726
193   A        -0.082  -0.232  -0.412  -0.175  -0.371  -0.608  -0.102  -0.322  -0.631
194   S        -0.489  -0.565  -0.469  -0.699  -0.857  -0.724  -0.728  -0.857  -0.726
195   L        -0.082  -0.067  -0.402  -0.218  -0.183  -0.688  -0.102  -0.080  -0.613
196   A         0.805   0.815   0.851   0.597   0.608   0.703   0.838   0.850   0.901
197   D         0.805   0.815   0.851   0.786   0.802   0.862   0.838   0.850   0.901
198   K        -0.489  -0.565  -0.469  -0.533  -0.666  -0.522  -0.728  -0.857  -0.726
199   L         0.805   0.815   0.851   0.589   0.615   0.696   0.838   0.850   0.901
200   D         0.805   0.815   0.851   0.786   0.802   0.862   0.838   0.850   0.901
201   M        -1.690  -1.618  -1.768  -1.690  -1.599  -1.768  -1.511  -1.425  -1.528
202   N        -0.917  -1.096  -1.207  -0.636  -0.886  -1.075  -0.885  -1.107  -1.232
203   F         0.805   0.815   0.851   1.026   1.034   1.062   0.838   0.850   0.901
204   A         0.805   0.815   0.851   0.597   0.608   0.703   0.838   0.850   0.901
205   L         0.805   0.815   0.851   0.589   0.615   0.696   0.838   0.850   0.901
206   I         0.805   0.815   0.851   0.646   0.664   0.745   0.838   0.850   0.901
207   H         0.805   0.815   0.851   1.000   1.013   1.041   0.838   0.850   0.901
208   K         0.805   0.815   0.851   0.813   0.826   0.884   0.838   0.850   0.901
209   E         0.805   0.815   0.851   0.879   0.890   0.939   0.838   0.850   0.901
210   R         0.805   0.815   0.851   0.894   0.899   0.952   0.838   0.850   0.901
211   Q         0.805   0.815   0.851   0.988   0.998   1.030   0.838   0.850   0.901
212   K        -0.082  -0.108  -0.406   0.048   0.017  -0.418  -0.102  -0.139  -0.620
213   A         0.805   0.815   0.851   0.597   0.608   0.703   0.838   0.850   0.901
214   N         0.805   0.815   0.851   0.876   0.886   0.937   0.838   0.850   0.901
215   E         0.805   0.815   0.851   0.879   0.890   0.939   0.838   0.850   0.901
216   V         0.805   0.815   0.851   0.709   0.720   0.797   0.838   0.850   0.901
217   S         0.805   0.815   0.851   0.757   0.772   0.837   0.838   0.850   0.901
218   R        -0.489  -0.500  -0.458  -0.487  -0.519  -0.492  -0.728  -0.749  -0.709
219   M         0.805   0.815   0.851   1.041   1.047   1.075   0.838   0.850   0.901
220   L        -0.082   0.053  -0.396  -0.107   0.067  -0.609  -0.102   0.084  -0.604
221   L         0.805   0.815   0.851   0.589   0.615   0.696   0.838   0.850   0.901
222   V         0.805   0.815   0.851   0.709   0.720   0.797   0.838   0.850   0.901
223   G         0.805   0.815   0.851   0.855   0.869   0.919   0.838   0.850   0.901
224   D         0.805   0.815   0.851   0.786   0.802   0.862   0.838   0.850   0.901
225   V         0.805   0.815   0.851   0.709   0.720   0.797   0.838   0.850   0.901
226   A        -2.385  -2.304  -2.214  -2.097  -1.989  -1.900  -1.981  -1.899  -1.713
227   G        -1.262  -1.305  -1.236  -1.223  -1.316  -1.192  -1.355  -1.415  -1.268
228   K        -0.082  -0.108  -0.406   0.073   0.045  -0.355  -0.102  -0.139  -0.620
229   S        -1.690  -1.856  -1.784  -1.602  -1.876  -1.822  -1.511  -1.679  -1.543
230   C        -0.082  -0.232  -0.412   0.230   0.005  -0.383  -0.102  -0.322  -0.631
231   L        -0.917  -1.077  -1.212  -1.007  -1.233  -1.458  -0.885  -1.084  -1.238
232   L         0.805   0.815   0.851   0.589   0.615   0.696   0.838   0.850   0.901
233   I        -0.489  -0.565  -0.469  -0.764  -0.903  -0.738  -0.728  -0.857  -0.726
234   D         0.805   0.815   0.851   0.786   0.802   0.862   0.838   0.850   0.901
235   D         0.805   0.815   0.851   0.786   0.802   0.862   0.838   0.850   0.901
236   M         0.805   0.815   0.851   1.041   1.047   1.075   0.838   0.850   0.901
237   A         0.805   0.815   0.851   0.597   0.608   0.703   0.838   0.850   0.901
238   D         0.805   0.815   0.851   0.786   0.802   0.862   0.838   0.850   0.901
239   T         0.805   0.815   0.851   0.850   0.870   0.915   0.838   0.850   0.901
240   C         0.805   0.815   0.851   1.044   1.049   1.077   0.838   0.850   0.901
241   G         0.805   0.815   0.851   0.855   0.869   0.919   0.838   0.850   0.901
242   T         0.805   0.815   0.851   0.850   0.870   0.915   0.838   0.850   0.901
243   L         0.805   0.815   0.851   0.589   0.615   0.696   0.838   0.850   0.901
244   V        -1.690  -1.856  -1.784  -1.547  -1.786  -1.671  -1.511  -1.679  -1.543
245   K        -0.082  -0.232  -0.412  -0.002  -0.214  -0.561  -0.102  -0.322  -0.631
246   A         0.805   0.815   0.851   0.597   0.608   0.703   0.838   0.850   0.901
247   C        -1.262  -1.028  -1.210  -1.363  -1.049  -1.242  -1.355  -1.043  -1.236
248   D        -0.917  -1.077  -1.212  -0.719  -0.935  -1.128  -0.885  -1.084  -1.238
249   T        -0.489  -0.500  -0.458  -0.568  -0.590  -0.576  -0.728  -0.749  -0.709
250   L         0.805   0.815   0.851   0.589   0.615   0.696   0.838   0.850   0.901
251   M        -1.262  -1.213  -1.231  -1.414  -1.373  -1.257  -1.355  -1.321  -1.262
252   D        -1.262  -1.260  -1.225  -1.216  -1.222  -1.184  -1.355  -1.347  -1.256
253   H        -1.367  -1.340  -1.229  -1.295  -1.250  -1.107  -1.511  -1.446  -1.259
254   G        -0.082  -0.131  -0.405   0.077   0.016  -0.419  -0.102  -0.171  -0.618
255   A         0.805   0.815   0.851   0.597   0.608   0.703   0.838   0.850   0.901
256   K        -0.489  -0.519  -0.467  -0.533  -0.588  -0.520  -0.728  -0.780  -0.724
257   E        -1.957  -2.036  -1.799  -1.910  -2.058  -1.730  -1.825  -1.876  -1.557
258   V         0.805   0.815   0.851   0.709   0.720   0.797   0.838   0.850   0.901
259   I        -1.957  -1.957  -1.793  -2.093  -2.055  -1.785  -1.825  -1.812  -1.552
260   A        -0.082  -0.131  -0.405  -0.141  -0.198  -0.510  -0.102  -0.171  -0.618
261   I        -0.082  -0.131  -0.405  -0.092  -0.143  -0.475  -0.102  -0.171  -0.618
262   V        -0.489  -0.500  -0.458  -0.728  -0.756  -0.708  -0.728  -0.749  -0.709
263   T         0.805   0.815   0.851   0.850   0.870   0.915   0.838   0.850   0.901
264   H         0.805   0.815   0.851   1.000   1.013   1.041   0.838   0.850   0.901
265   G         0.805   0.815   0.851   0.855   0.869   0.919   0.838   0.850   0.901
266   I         0.805   0.815   0.851   0.646   0.664   0.745   0.838   0.850   0.901
267   F        -0.489  -0.565  -0.469  -0.443  -0.611  -0.543  -0.728  -0.857  -0.726
268   S         0.805   0.815   0.851   0.757   0.772   0.837   0.838   0.850   0.901
269   G        -0.082  -0.067  -0.402   0.067   0.090  -0.437  -0.102  -0.080  -0.613
270   S        -1.957  -2.036  -1.799  -1.864  -1.957  -1.589  -1.825  -1.876  -1.557
271   A         0.805   0.815   0.851   0.597   0.608   0.703   0.838   0.850   0.901
272   R        -1.957  -1.795  -1.781  -2.002  -1.776  -1.711  -1.825  -1.630  -1.541
273   E        -1.262  -1.334  -1.232  -1.125  -1.221  -1.092  -1.355  -1.418  -1.263
274   K        -1.262  -1.386  -1.236  -1.250  -1.443  -1.225  -1.355  -1.489  -1.268
275   L        -0.489  -0.565  -0.469  -0.844  -0.976  -0.813  -0.728  -0.857  -0.726
276   I        -1.690  -1.361  -1.759  -1.491  -1.018  -1.709  -1.511  -1.139  -1.520
277   N        -0.917  -1.077  -1.212  -0.658  -0.881  -1.128  -0.885  -1.084  -1.238
278   S         0.805   0.815   0.851   0.757   0.772   0.837   0.838   0.850   0.901
279   R        -2.385  -2.391  -2.216  -2.145  -2.200  -1.942  -1.981  -1.972  -1.715
280   L         0.805   0.815   0.851   0.589   0.615   0.696   0.838   0.850   0.901
281   S        -1.957  -1.966  -1.793  -1.978  -1.981  -1.747  -1.825  -1.817  -1.552
282   R        -0.489  -0.344  -0.435  -0.533  -0.309  -0.467  -0.728  -0.494  -0.669
283   I        -0.672  -0.662  -0.477  -1.103  -1.085  -0.749  -1.041  -1.027  -0.740
284   V        -0.672  -0.663  -0.478  -1.089  -1.087  -0.752  -1.041  -1.028  -0.742
285   C        -0.082  -0.232  -0.412   0.247   0.030  -0.337  -0.102  -0.322  -0.631
286   T         0.805   0.815   0.851   0.850   0.870   0.915   0.838   0.850   0.901
287   N         0.805   0.815   0.851   0.876   0.886   0.937   0.838   0.850   0.901
288   T        -0.489  -0.500  -0.458  -0.550  -0.569  -0.551  -0.728  -0.749  -0.709
289   V        -1.690  -1.828  -1.784  -1.601  -1.830  -1.765  -1.511  -1.651  -1.543
290   P         0.805   0.815   0.851   0.977   0.988   1.022   0.838   0.850   0.901
291   V        -1.262  -1.300  -1.234  -1.322  -1.371  -1.277  -1.355  -1.408  -1.266
292   D        -0.917  -0.953  -1.204  -0.706  -0.746  -1.091  -0.885  -0.925  -1.228
293   L        -2.547  -2.425  -2.223  -2.557  -2.319  -2.029  -2.138  -2.010  -1.720
294   D        -1.367  -1.324  -1.232  -1.535  -1.440  -1.328  -1.511  -1.430  -1.263
295   L        -1.690  -1.734  -1.776  -1.687  -1.737  -1.772  -1.511  -1.556  -1.536
296   D        -2.975  -2.800  -2.573  -2.770  -2.546  -2.211  -2.294  -2.138  -1.831
297   I        -1.957  -2.036  -1.799  -1.981  -2.076  -1.720  -1.825  -1.876  -1.557
298   -         0.805   0.815   0.851   1.029   1.038   1.065   0.838   0.850   0.901
299   -        -1.444  -1.413  -1.240  -1.409  -1.367  -1.160  -1.560  -1.511  -1.272
300   -         0.805   0.815   0.851   0.798   0.816   0.872   0.838   0.850   0.901
301   V        -1.529  -1.462  -1.242  -1.998  -1.887  -1.509  -1.668  -1.580  -1.275
302   D        -0.672  -0.663  -0.478  -0.879  -0.859  -0.559  -1.041  -1.028  -0.742
303   Q        -1.957  -1.977  -1.796  -1.717  -1.757  -1.527  -1.825  -1.826  -1.555
304   V        -1.262  -1.171  -1.207  -1.520  -1.345  -1.433  -1.355  -1.208  -1.232
305   D         0.805   0.815   0.851   0.786   0.802   0.862   0.838   0.850   0.901
306   I        -0.082  -0.108  -0.406  -0.150  -0.179  -0.624  -0.102  -0.139  -0.620
307   S         0.805   0.815   0.851   0.757   0.772   0.837   0.838   0.850   0.901
308   P        -1.690  -1.828  -1.784  -1.357  -1.578  -1.635  -1.511  -1.651  -1.543
309   T        -0.082  -0.232  -0.412   0.054  -0.147  -0.482  -0.102  -0.322  -0.631
310   I        -0.082   0.053  -0.396  -0.218  -0.032  -0.678  -0.102   0.084  -0.604
311   A         0.805   0.815   0.851   0.597   0.608   0.703   0.838   0.850   0.901
312   E         0.805   0.815   0.851   0.879   0.890   0.939   0.838   0.850   0.901
313   A        -0.082  -0.232  -0.412  -0.141  -0.325  -0.519  -0.102  -0.322  -0.631
314   I         0.805   0.815   0.851   0.646   0.664   0.745   0.838   0.850   0.901
315   R        -0.082   0.076  -0.395   0.116   0.301  -0.373  -0.102   0.115  -0.602
316   R         0.805   0.815   0.851   0.894   0.899   0.952   0.838   0.850   0.901
317   L        -0.082  -0.232  -0.412  -0.218  -0.414  -0.708  -0.102  -0.322  -0.631
318   H         0.805   0.815   0.851   1.000   1.013   1.041   0.838   0.850   0.901
319   N        -0.082  -0.232  -0.412   0.129  -0.062  -0.337  -0.102  -0.322  -0.631
320   G         0.805   0.815   0.851   0.855   0.869   0.919   0.838   0.850   0.901
321   E         0.805   0.815   0.851   0.879   0.890   0.939   0.838   0.850   0.901
322   S         0.805   0.815   0.851   0.757   0.772   0.837   0.838   0.850   0.901
323   V         0.805   0.815   0.851   0.709   0.720   0.797   0.838   0.850   0.901
324   S         0.805   0.815   0.851   0.757   0.772   0.837   0.838   0.850   0.901
325   Y        -0.082  -0.232  -0.412   0.257   0.045  -0.329  -0.102  -0.322  -0.631
326   L         0.805   0.815   0.851   0.589   0.615   0.696   0.838   0.850   0.901
327   F         0.805   0.815   0.851   1.026   1.034   1.062   0.838   0.850   0.901
328   T        -1.957  -2.036  -1.799  -1.826  -1.939  -1.601  -1.825  -1.876  -1.557
329   H        -1.367  -1.405  -1.234  -1.306  -1.361  -1.134  -1.511  -1.516  -1.265
330   A        -0.082  -0.131  -0.405  -0.199  -0.265  -0.660  -0.102  -0.171  -0.618
331   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
332   P        -0.082   0.040  -0.399   0.164   0.320  -0.404  -0.102   0.068  -0.608
333   V        -2.385  -2.268  -2.206  -2.335  -2.155  -2.040  -1.981  -1.858  -1.707
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P38620
Output conservation file - output/P38620
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
