1     M         1.799   1.812   1.828   2.249   2.271   2.298   1.931   1.946   1.968
2     D         1.799   1.812   1.828   1.602   1.630   1.649   1.931   1.946   1.968
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     R         1.799   1.812   1.828   2.008   2.026   2.057   1.931   1.946   1.968
8     D         0.131   0.080   0.077   0.052   0.001  -0.001   0.007  -0.074  -0.080
9     T         0.131   0.080   0.077  -0.042  -0.163  -0.179   0.007  -0.074  -0.080
10    K         1.799   1.812   1.828   1.971   1.996   2.020   1.931   1.946   1.968
11    L         1.799   1.812   1.828   1.425   1.439   1.472   1.931   1.946   1.968
12    A         0.131   0.188   0.120  -0.209  -0.134  -0.216   0.007   0.097  -0.011
13    F        -1.080  -1.070  -1.058  -0.595  -0.570  -0.555  -0.955  -0.937  -0.914
14    R         1.799   1.812   1.828   2.008   2.026   2.057   1.931   1.946   1.968
15    L         0.131   0.080   0.077  -0.228  -0.302  -0.294   0.007  -0.074  -0.080
16    R         1.799   1.812   1.828   2.008   2.026   2.057   1.931   1.946   1.968
17    G         1.799   1.812   1.828   2.177   2.195   2.226   1.931   1.946   1.968
18    S         1.799   1.812   1.828   1.828   1.856   1.876   1.931   1.946   1.968
19    H         0.131   0.080   0.077   0.503   0.416   0.405   0.007  -0.074  -0.080
20    S         1.799   1.812   1.828   1.828   1.856   1.876   1.931   1.946   1.968
21    R         1.799   1.812   1.828   2.008   2.026   2.057   1.931   1.946   1.968
22    R        -1.080  -1.070  -1.058  -0.982  -0.969  -0.943  -0.955  -0.937  -0.914
23    T        -1.080  -1.070  -1.058  -0.959  -0.947  -0.920  -0.955  -0.937  -0.914
24    D         0.131   0.157   0.108  -0.064  -0.015  -0.094   0.007   0.049  -0.030
25    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    -        -0.017  -0.011   0.007   0.175   0.185   0.218  -0.234  -0.223  -0.194
35    -         1.799   1.812   1.828   1.646   1.674   1.693   1.931   1.946   1.968
36    -        -0.017  -0.011   0.007  -0.026  -0.018   0.016  -0.234  -0.223  -0.194
37    -        -0.017  -0.011   0.007  -0.245  -0.231  -0.204  -0.234  -0.223  -0.194
38    -        -0.017  -0.011   0.007  -0.432  -0.429  -0.392  -0.234  -0.223  -0.194
39    -        -0.017  -0.011   0.007  -0.253  -0.239  -0.212  -0.234  -0.223  -0.194
40    -        -0.017  -0.011   0.007   0.076   0.085   0.118  -0.234  -0.223  -0.194
41    -        -0.017  -0.011   0.007  -0.098  -0.090  -0.056  -0.234  -0.223  -0.194
42    -        -0.017  -0.011   0.007  -0.406  -0.402  -0.365  -0.234  -0.223  -0.194
43    D        -1.080  -1.070  -1.058  -1.163  -1.118  -1.125  -0.955  -0.937  -0.914
44    I        -1.080  -1.070  -1.058  -0.931  -0.918  -0.892  -0.955  -0.937  -0.914
45    D         1.799   1.812   1.828   1.602   1.630   1.649   1.931   1.946   1.968
46    D        -1.080  -1.070  -1.058  -0.954  -0.906  -0.915  -0.955  -0.937  -0.914
47    D         1.799   1.812   1.828   1.602   1.630   1.649   1.931   1.946   1.968
48    V         0.131   0.080   0.077   0.038  -0.087  -0.103   0.007  -0.074  -0.080
49    I        -1.080  -1.070  -1.058  -1.139  -1.108  -1.101  -0.955  -0.937  -0.914
50    V         0.131   0.080   0.077   0.247   0.154   0.149   0.007  -0.074  -0.080
51    F         0.131   0.188   0.120   0.031   0.116   0.026   0.007   0.097  -0.011
52    K        -1.080  -1.070  -1.058  -0.931  -0.917  -0.892  -0.955  -0.937  -0.914
53    T        -1.080  -1.070  -1.058  -1.139  -1.107  -1.101  -0.955  -0.937  -0.914
54    P        -1.080  -1.070  -1.058  -1.139  -1.165  -1.101  -0.955  -0.937  -0.914
55    N         0.131   0.080   0.077   0.102   0.018   0.010   0.007  -0.074  -0.080
56    A         0.131   0.080   0.077   0.295   0.204   0.199   0.007  -0.074  -0.080
57    V        -0.017  -0.011   0.007   0.063   0.073   0.106  -0.234  -0.223  -0.194
58    Y        -0.017  -0.011   0.007  -0.077  -0.069  -0.035  -0.234  -0.223  -0.194
59    R        -0.017  -0.011   0.007  -0.263  -0.258  -0.222  -0.234  -0.223  -0.194
60    E        -0.017  -0.011   0.007  -0.006   0.002   0.036  -0.234  -0.223  -0.194
61    E        -0.017  -0.011   0.007  -0.165  -0.150  -0.123  -0.234  -0.223  -0.194
62    N         0.131   0.080   0.077   0.227   0.161   0.159   0.007  -0.074  -0.080
63    S        -1.080  -1.070  -1.058  -0.877  -0.837  -0.838  -0.955  -0.937  -0.914
64    P         0.131   0.188   0.120  -0.005   0.086  -0.013   0.007   0.097  -0.011
65    I         0.131   0.157   0.108   0.203   0.243   0.167   0.007   0.049  -0.030
66    Q         0.131   0.157   0.108   0.206   0.253   0.160   0.007   0.049  -0.030
67    S        -1.080  -1.070  -1.058  -0.927  -0.900  -0.888  -0.955  -0.937  -0.914
68    P         0.131   0.157   0.108   0.220   0.280   0.161   0.007   0.049  -0.030
69    V         1.799   1.812   1.828   1.972   1.994   2.021   1.931   1.946   1.968
70    Q        -0.017  -0.011   0.007   0.003   0.015   0.045  -0.234  -0.223  -0.194
71    P         1.799   1.812   1.828   2.074   2.097   2.123   1.931   1.946   1.968
72    I        -0.017  -0.011   0.007  -0.042  -0.030   0.000  -0.234  -0.223  -0.194
73    L        -0.017  -0.011   0.007  -0.172  -0.161  -0.130  -0.234  -0.223  -0.194
74    S        -0.017  -0.011   0.007  -0.395  -0.386  -0.355  -0.234  -0.223  -0.194
75    S         0.131   0.157   0.108   0.073   0.127   0.030   0.007   0.049  -0.030
76    P         0.131   0.157   0.108   0.369   0.418   0.326   0.007   0.049  -0.030
77    K        -1.080  -1.070  -1.058  -0.940  -0.942  -0.902  -0.955  -0.937  -0.914
78    L        -1.080  -1.070  -1.058  -1.193  -1.154  -1.155  -0.955  -0.937  -0.914
79    A         0.131   0.080   0.077   0.312   0.224   0.220   0.007  -0.074  -0.080
80    N        -1.080  -1.070  -1.058  -1.238  -1.230  -1.200  -0.955  -0.937  -0.914
81    S        -1.080  -1.070  -1.058  -1.105  -1.093  -1.067  -0.955  -0.937  -0.914
82    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
83    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
84    F         0.131   0.157   0.108   0.213   0.266   0.144   0.007   0.049  -0.030
85    E         0.131   0.188   0.120  -0.078   0.014  -0.091   0.007   0.097  -0.011
86    F        -1.080  -1.070  -1.058  -1.067  -1.099  -1.028  -0.955  -0.937  -0.914
87    P         0.131   0.080   0.077   0.315   0.226   0.206   0.007  -0.074  -0.080
88    I        -1.080  -1.070  -1.058  -0.913  -0.894  -0.874  -0.955  -0.937  -0.914
89    T        -1.080  -1.070  -1.058  -0.718  -0.685  -0.678  -0.955  -0.937  -0.914
90    T         0.131   0.188   0.120  -0.100  -0.004  -0.115   0.007   0.097  -0.011
91    N        -1.080  -1.070  -1.058  -0.877  -0.838  -0.838  -0.955  -0.937  -0.914
92    N        -1.080  -1.070  -1.058  -1.350  -1.364  -1.313  -0.955  -0.937  -0.914
93    V        -1.080  -1.070  -1.058  -0.629  -0.593  -0.589  -0.955  -0.937  -0.914
94    N        -1.080  -1.070  -1.058  -1.034  -1.029  -0.995  -0.955  -0.937  -0.914
95    A        -1.080  -1.070  -1.058  -0.890  -0.872  -0.851  -0.955  -0.937  -0.914
96    Q         0.131   0.080   0.077   0.292   0.208   0.204   0.007  -0.074  -0.080
97    D        -1.080  -1.070  -1.058  -1.005  -0.978  -0.967  -0.955  -0.937  -0.914
98    R        -1.080  -1.070  -1.058  -0.908  -0.885  -0.869  -0.955  -0.937  -0.914
99    H        -1.080  -1.070  -1.058  -0.832  -0.833  -0.793  -0.955  -0.937  -0.914
100   E         0.131   0.157   0.108   0.213   0.252   0.172   0.007   0.049  -0.030
101   H        -1.080  -1.070  -1.058  -0.814  -0.829  -0.775  -0.955  -0.937  -0.914
102   G        -1.080  -1.070  -1.058  -1.052  -1.061  -1.014  -0.955  -0.937  -0.914
103   Y         0.131   0.188   0.120   0.308   0.390   0.301   0.007   0.097  -0.011
104   Q        -1.080  -1.070  -1.058  -1.183  -1.177  -1.145  -0.955  -0.937  -0.914
105   P        -1.080  -1.070  -1.058  -0.701  -0.667  -0.661  -0.955  -0.937  -0.914
106   L        -1.080  -1.070  -1.058  -1.115  -1.073  -1.076  -0.955  -0.937  -0.914
107   D         0.131   0.080   0.077  -0.104  -0.178  -0.187   0.007  -0.074  -0.080
108   A        -1.080  -1.070  -1.058  -0.718  -0.693  -0.678  -0.955  -0.937  -0.914
109   E        -1.080  -1.070  -1.058  -1.034  -1.034  -0.995  -0.955  -0.937  -0.914
110   D        -1.080  -1.070  -1.058  -1.086  -1.055  -1.047  -0.955  -0.937  -0.914
111   Y         0.131   0.080   0.077   0.490   0.400   0.390   0.007  -0.074  -0.080
112   P        -1.080  -1.070  -1.058  -0.819  -0.800  -0.779  -0.955  -0.937  -0.914
113   M        -1.080  -1.070  -1.058  -0.562  -0.559  -0.522  -0.955  -0.937  -0.914
114   I         0.131   0.188   0.120   0.244   0.338   0.224   0.007   0.097  -0.011
115   D         0.131   0.080   0.077  -0.137  -0.213  -0.227   0.007  -0.074  -0.080
116   S         0.131   0.188   0.120   0.244   0.347   0.221   0.007   0.097  -0.011
117   E        -1.080  -1.070  -1.058  -0.675  -0.649  -0.635  -0.955  -0.937  -0.914
118   N        -1.080  -1.070  -1.058  -1.005  -0.979  -0.967  -0.955  -0.937  -0.914
119   K        -1.080  -1.070  -1.058  -0.886  -0.872  -0.847  -0.955  -0.937  -0.914
120   S         0.131   0.080   0.077   0.109   0.029   0.017   0.007  -0.074  -0.080
121   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
122   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
123   L         1.799   1.812   1.828   1.427   1.453   1.474   1.931   1.946   1.968
124   I        -0.017  -0.011   0.007  -0.022  -0.014   0.020  -0.234  -0.223  -0.194
125   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
126   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
127   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
128   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
129   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
130   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
131   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
132   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
133   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
134   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
135   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
136   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
137   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
138   T        -0.017  -0.011   0.007  -0.093  -0.085  -0.051  -0.234  -0.223  -0.194
139   T        -1.080  -1.070  -1.058  -1.233  -1.224  -1.195  -0.955  -0.937  -0.914
140   R        -1.080  -1.070  -1.058  -0.868  -0.861  -0.829  -0.955  -0.937  -0.914
141   Y         0.131   0.080   0.077   0.454   0.360   0.347   0.007  -0.074  -0.080
142   N        -1.080  -1.070  -1.058  -1.188  -1.149  -1.150  -0.955  -0.937  -0.914
143   F         1.799   1.812   1.828   2.162   2.186   2.212   1.931   1.946   1.968
144   D         0.131   0.157   0.108  -0.078  -0.033  -0.110   0.007   0.049  -0.030
145   D         0.131   0.080   0.077  -0.134  -0.206  -0.222   0.007  -0.074  -0.080
146   I         0.131   0.080   0.077   0.329   0.261   0.265   0.007  -0.074  -0.080
147   P         0.131   0.080   0.077   0.349   0.261   0.246   0.007  -0.074  -0.080
148   I        -1.080  -1.070  -1.058  -1.248  -1.270  -1.210  -0.955  -0.937  -0.914
149   R         0.131   0.188   0.120   0.161   0.256   0.147   0.007   0.097  -0.011
150   Q         0.131   0.157   0.108   0.292   0.333   0.255   0.007   0.049  -0.030
151   L         1.799   1.812   1.828   1.425   1.439   1.472   1.931   1.946   1.968
152   S         0.131   0.157   0.108   0.254   0.301   0.231   0.007   0.049  -0.030
153   S         0.131   0.080   0.077   0.109   0.029   0.017   0.007  -0.074  -0.080
154   S         0.131   0.080   0.077   0.199   0.136   0.125   0.007  -0.074  -0.080
155   I         0.131   0.080   0.077  -0.049  -0.171  -0.186   0.007  -0.074  -0.080
156   T         1.799   1.812   1.828   1.896   1.916   1.944   1.931   1.946   1.968
157   S         1.799   1.812   1.828   1.828   1.856   1.876   1.931   1.946   1.968
158   V         0.131   0.080   0.077   0.408   0.338   0.341   0.007  -0.074  -0.080
159   T         0.131   0.080   0.077   0.223   0.141   0.139   0.007  -0.074  -0.080
160   T         1.799   1.812   1.828   1.896   1.916   1.944   1.931   1.946   1.968
161   I         1.799   1.812   1.828   1.888   1.907   1.937   1.931   1.946   1.968
162   D         0.131   0.157   0.108   0.052   0.096   0.034   0.007   0.049  -0.030
163   V         1.799   1.812   1.828   1.979   1.997   2.027   1.931   1.946   1.968
164   L         1.799   1.812   1.828   1.425   1.439   1.472   1.931   1.946   1.968
165   S        -1.080  -1.070  -1.058  -0.931  -0.903  -0.892  -0.955  -0.937  -0.914
166   S        -1.080  -1.070  -1.058  -0.908  -0.881  -0.869  -0.955  -0.937  -0.914
167   L         0.131   0.157   0.108  -0.270  -0.237  -0.300   0.007   0.049  -0.030
168   F         0.131   0.080   0.077   0.213   0.089   0.066   0.007  -0.074  -0.080
169   I        -1.080  -1.070  -1.058  -0.982  -0.966  -0.943  -0.955  -0.937  -0.914
170   N         0.131   0.080   0.077   0.102   0.018   0.010   0.007  -0.074  -0.080
171   L         0.131   0.080   0.077  -0.224  -0.299  -0.290   0.007  -0.074  -0.080
172   F        -1.080  -1.070  -1.058  -1.124  -1.115  -1.086  -0.955  -0.937  -0.914
173   E        -1.080  -1.070  -1.058  -1.218  -1.243  -1.180  -0.955  -0.937  -0.914
174   N         0.131   0.080   0.077   0.140   0.061   0.056   0.007  -0.074  -0.080
175   D         1.799   1.812   1.828   1.557   1.576   1.604   1.931   1.946   1.968
176   L         0.131   0.080   0.077  -0.266  -0.346  -0.340   0.007  -0.074  -0.080
177   I         1.799   1.812   1.828   1.888   1.907   1.937   1.931   1.946   1.968
178   P         0.131   0.080   0.077   0.369   0.282   0.270   0.007  -0.074  -0.080
179   Q         0.131   0.080   0.077   0.261   0.171   0.167   0.007  -0.074  -0.080
180   A         0.131   0.080   0.077   0.325   0.239   0.236   0.007  -0.074  -0.080
181   L         0.131   0.080   0.077  -0.266  -0.346  -0.340   0.007  -0.074  -0.080
182   K        -1.080  -1.070  -1.058  -1.001  -0.984  -0.962  -0.955  -0.937  -0.914
183   D        -1.080  -1.070  -1.058  -1.067  -1.029  -1.028  -0.955  -0.937  -0.914
184   F         1.799   1.812   1.828   2.162   2.186   2.212   1.931   1.946   1.968
185   N         1.799   1.812   1.828   1.820   1.844   1.868   1.931   1.946   1.968
186   K        -1.080  -1.070  -1.058  -0.722  -0.708  -0.683  -0.955  -0.937  -0.914
187   S        -1.080  -1.070  -1.058  -0.977  -0.946  -0.939  -0.955  -0.937  -0.914
188   D        -1.080  -1.070  -1.058  -1.005  -0.954  -0.967  -0.955  -0.937  -0.914
189   D        -1.080  -1.070  -1.058  -1.283  -1.241  -1.246  -0.955  -0.937  -0.914
190   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
191   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
192   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
193   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
194   D        -1.080  -1.070  -1.058  -1.158  -1.108  -1.120  -0.955  -0.937  -0.914
195   Q         0.131   0.080   0.077   0.292   0.206   0.204   0.007  -0.074  -0.080
196   F         0.131   0.188   0.120  -0.130  -0.061  -0.131   0.007   0.097  -0.011
197   R         0.131   0.157   0.108   0.308   0.350   0.269   0.007   0.049  -0.030
198   K         1.799   1.812   1.828   1.920   1.942   1.969   1.931   1.946   1.968
199   L         0.131   0.157   0.108  -0.086  -0.057  -0.096   0.007   0.049  -0.030
200   L        -1.080  -1.070  -1.058  -1.294  -1.241  -1.256  -0.955  -0.937  -0.914
201   Y        -1.080  -1.070  -1.058  -0.895  -0.927  -0.856  -0.955  -0.937  -0.914
202   K         1.799   1.812   1.828   1.971   1.996   2.020   1.931   1.946   1.968
203   L         1.799   1.812   1.828   1.425   1.439   1.472   1.931   1.946   1.968
204   D         0.131   0.080   0.077  -0.078  -0.151  -0.156   0.007  -0.074  -0.080
205   L        -1.080  -1.070  -1.058  -1.067  -1.038  -1.028  -0.955  -0.937  -0.914
206   R         0.131   0.080   0.077   0.308   0.221   0.216   0.007  -0.074  -0.080
207   L         0.131   0.188   0.120  -0.049   0.062  -0.086   0.007   0.097  -0.011
208   F         0.131   0.080   0.077   0.213   0.089   0.066   0.007  -0.074  -0.080
209   Q         0.131   0.080   0.077   0.241   0.150   0.143   0.007  -0.074  -0.080
210   T        -1.080  -1.070  -1.058  -0.701  -0.660  -0.661  -0.955  -0.937  -0.914
211   I        -1.080  -1.070  -1.058  -1.124  -1.082  -1.086  -0.955  -0.937  -0.914
212   S        -1.080  -1.070  -1.058  -1.268  -1.281  -1.230  -0.955  -0.937  -0.914
213   D        -1.080  -1.070  -1.058  -0.959  -0.905  -0.920  -0.955  -0.937  -0.914
214   Q         1.799   1.812   1.828   1.971   1.992   2.020   1.931   1.946   1.968
215   M        -1.080  -1.070  -1.058  -1.105  -1.098  -1.067  -0.955  -0.937  -0.914
216   T         0.131   0.080   0.077   0.206   0.124   0.118   0.007  -0.074  -0.080
217   R        -1.080  -1.070  -1.058  -0.841  -0.833  -0.802  -0.955  -0.937  -0.914
218   D         1.799   1.812   1.828   1.602   1.630   1.649   1.931   1.946   1.968
219   L         1.799   1.812   1.828   1.425   1.439   1.472   1.931   1.946   1.968
220   K        -1.080  -1.070  -1.058  -1.144  -1.119  -1.106  -0.955  -0.937  -0.914
221   D         0.131   0.080   0.077  -0.100  -0.174  -0.182   0.007  -0.074  -0.080
222   I         0.131   0.157   0.108  -0.049  -0.002  -0.114   0.007   0.049  -0.030
223   L         0.131   0.080   0.077  -0.301  -0.380  -0.381   0.007  -0.074  -0.080
224   D         0.131   0.080   0.077  -0.078  -0.151  -0.156   0.007  -0.074  -0.080
225   I         0.131   0.080   0.077  -0.049  -0.171  -0.186   0.007  -0.074  -0.080
226   N         1.799   1.812   1.828   1.820   1.844   1.868   1.931   1.946   1.968
227   V        -1.080  -1.070  -1.058  -1.193  -1.216  -1.155  -0.955  -0.937  -0.914
228   S         0.131   0.157   0.108   0.161   0.210   0.128   0.007   0.049  -0.030
229   N         1.799   1.812   1.828   1.820   1.844   1.868   1.931   1.946   1.968
230   N         1.799   1.812   1.828   1.820   1.844   1.868   1.931   1.946   1.968
231   E         0.131   0.080   0.077   0.080  -0.027  -0.043   0.007  -0.074  -0.080
232   L         1.799   1.812   1.828   1.425   1.439   1.472   1.931   1.946   1.968
233   C         0.131   0.080   0.077   0.349   0.222   0.197   0.007  -0.074  -0.080
234   Y         1.799   1.812   1.828   2.206   2.230   2.255   1.931   1.946   1.968
235   Q         0.131   0.080   0.077   0.292   0.206   0.204   0.007  -0.074  -0.080
236   L         1.799   1.812   1.828   1.425   1.439   1.472   1.931   1.946   1.968
237   K         1.799   1.812   1.828   1.971   1.996   2.020   1.931   1.946   1.968
238   Q         0.131   0.157   0.108   0.261   0.303   0.221   0.007   0.049  -0.030
239   V        -1.080  -1.070  -1.058  -1.248  -1.232  -1.210  -0.955  -0.937  -0.914
240   L        -1.080  -1.070  -1.058  -1.345  -1.306  -1.308  -0.955  -0.937  -0.914
241   A         0.131   0.080   0.077   0.066  -0.057  -0.075   0.007  -0.074  -0.080
242   R        -1.080  -1.070  -1.058  -1.273  -1.296  -1.235  -0.955  -0.937  -0.914
243   K         0.131   0.157   0.108   0.210   0.262   0.164   0.007   0.049  -0.030
244   E        -1.080  -1.070  -1.058  -0.977  -0.969  -0.939  -0.955  -0.937  -0.914
245   D        -1.080  -1.070  -1.058  -1.550  -1.502  -1.513  -0.955  -0.937  -0.914
246   L         1.799   1.812   1.828   1.425   1.439   1.472   1.931   1.946   1.968
247   N         0.131   0.080   0.077   0.070  -0.013  -0.028   0.007  -0.074  -0.080
248   Q        -1.080  -1.070  -1.058  -0.845  -0.826  -0.806  -0.955  -0.937  -0.914
249   Q        -1.080  -1.070  -1.058  -0.973  -0.962  -0.934  -0.955  -0.937  -0.914
250   I         0.131   0.188   0.120  -0.270  -0.190  -0.282   0.007   0.097  -0.011
251   I         0.131   0.080   0.077  -0.049  -0.171  -0.186   0.007  -0.074  -0.080
252   S        -1.080  -1.070  -1.058  -1.158  -1.150  -1.120  -0.955  -0.937  -0.914
253   V         1.799   1.812   1.828   1.979   1.997   2.027   1.931   1.946   1.968
254   R         1.799   1.812   1.828   2.008   2.026   2.057   1.931   1.946   1.968
255   N        -1.080  -1.070  -1.058  -1.048  -1.023  -1.009  -0.955  -0.937  -0.914
256   E         0.131   0.080   0.077   0.264   0.178   0.178   0.007  -0.074  -0.080
257   I         0.131   0.157   0.108   0.308   0.347   0.284   0.007   0.049  -0.030
258   Q         0.131   0.080   0.077   0.210   0.119   0.106   0.007  -0.074  -0.080
259   E        -1.080  -1.070  -1.058  -1.019  -1.006  -0.981  -0.955  -0.937  -0.914
260   L        -0.017  -0.011   0.007  -0.379  -0.369  -0.338  -0.234  -0.223  -0.194
261   K         1.799   1.812   1.828   1.920   1.942   1.969   1.931   1.946   1.968
262   A         0.131   0.188   0.120   0.503   0.603   0.484   0.007   0.097  -0.011
263   G         0.131   0.080   0.077   0.448   0.350   0.345   0.007  -0.074  -0.080
264   K         0.131   0.188   0.120   0.461   0.558   0.441   0.007   0.097  -0.011
265   D        -1.080  -1.070  -1.058  -1.015  -0.960  -0.976  -0.955  -0.937  -0.914
266   W        -1.080  -1.070  -1.058  -0.748  -0.751  -0.709  -0.955  -0.937  -0.914
267   H         0.131   0.080   0.077   0.422   0.325   0.308   0.007  -0.074  -0.080
268   D        -1.080  -1.070  -1.058  -1.067  -1.023  -1.028  -0.955  -0.937  -0.914
269   L         1.799   1.812   1.828   1.425   1.439   1.472   1.931   1.946   1.968
270   Q        -1.080  -1.070  -1.058  -0.973  -0.962  -0.934  -0.955  -0.937  -0.914
271   N         0.131   0.080   0.077   0.123   0.040   0.035   0.007  -0.074  -0.080
272   E         0.131   0.157   0.108   0.080   0.128   0.024   0.007   0.049  -0.030
273   Q         0.131   0.157   0.108   0.292   0.333   0.255   0.007   0.049  -0.030
274   A         0.131   0.080   0.077   0.312   0.224   0.220   0.007  -0.074  -0.080
275   K        -1.080  -1.070  -1.058  -0.936  -0.909  -0.897  -0.955  -0.937  -0.914
276   L         0.131   0.157   0.108  -0.270  -0.237  -0.300   0.007   0.049  -0.030
277   N         0.131   0.080   0.077   0.137   0.059   0.052   0.007  -0.074  -0.080
278   D        -1.080  -1.070  -1.058  -1.283  -1.242  -1.246  -0.955  -0.937  -0.914
279   K         0.131   0.080   0.077   0.362   0.292   0.288   0.007  -0.074  -0.080
280   V        -1.080  -1.070  -1.058  -0.913  -0.894  -0.874  -0.955  -0.937  -0.914
281   K        -1.080  -1.070  -1.058  -0.845  -0.826  -0.806  -0.955  -0.937  -0.914
282   L         0.131   0.080   0.077  -0.270  -0.351  -0.344   0.007  -0.074  -0.080
283   N         1.799   1.812   1.828   1.820   1.844   1.868   1.931   1.946   1.968
284   K        -1.080  -1.070  -1.058  -0.863  -0.850  -0.824  -0.955  -0.937  -0.914
285   R        -1.080  -1.070  -1.058  -1.173  -1.200  -1.135  -0.955  -0.937  -0.914
286   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
287   L         1.799   1.812   1.828   1.425   1.439   1.472   1.931   1.946   1.968
288   N        -1.080  -1.070  -1.058  -1.043  -1.022  -1.004  -0.955  -0.937  -0.914
289   D        -1.080  -1.070  -1.058  -1.110  -1.073  -1.072  -0.955  -0.937  -0.914
290   L         0.131   0.080   0.077  -0.209  -0.283  -0.272   0.007  -0.074  -0.080
291   T         0.131   0.080   0.077   0.168   0.078   0.073   0.007  -0.074  -0.080
292   S        -1.080  -1.070  -1.058  -1.203  -1.196  -1.165  -0.955  -0.937  -0.914
293   T         0.131   0.157   0.108   0.223   0.264   0.189   0.007   0.049  -0.030
294   L         0.131   0.080   0.077  -0.270  -0.351  -0.344   0.007  -0.074  -0.080
295   L         0.131   0.080   0.077  -0.270  -0.351  -0.344   0.007  -0.074  -0.080
296   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
297   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
298   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
299   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
300   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
301   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
302   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
303   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
304   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
305   M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
306   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
307   Q        -0.017  -0.011   0.007  -0.133  -0.122  -0.092  -0.234  -0.223  -0.194
308   D         1.799   1.812   1.828   1.557   1.576   1.604   1.931   1.946   1.968
309   S        -0.017  -0.011   0.007  -0.242  -0.232  -0.201  -0.234  -0.223  -0.194
310   E         1.799   1.812   1.828   1.951   1.973   2.000   1.931   1.946   1.968
311   D         0.131   0.080   0.077  -0.137  -0.213  -0.227   0.007  -0.074  -0.080
312   D         0.131   0.080   0.077  -0.137  -0.213  -0.227   0.007  -0.074  -0.080
313   S        -1.080  -1.070  -1.058  -1.048  -1.026  -1.009  -0.955  -0.937  -0.914
314   I        -1.080  -1.070  -1.058  -1.228  -1.249  -1.190  -0.955  -0.937  -0.914
315   R        -1.080  -1.070  -1.058  -0.991  -0.953  -0.953  -0.955  -0.937  -0.914
316   D        -1.080  -1.070  -1.058  -0.991  -0.941  -0.953  -0.955  -0.937  -0.914
317   D         0.131   0.157   0.108  -0.005   0.043  -0.029   0.007   0.049  -0.030
318   S        -1.080  -1.070  -1.058  -1.345  -1.313  -1.308  -0.955  -0.937  -0.914
319   N        -1.080  -1.070  -1.058  -1.095  -1.072  -1.057  -0.955  -0.937  -0.914
320   I         0.131   0.080   0.077   0.165   0.075   0.070   0.007  -0.074  -0.080
321   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
322   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
323   L         0.131   0.080   0.077  -0.130  -0.191  -0.178   0.007  -0.074  -0.080
324   D         0.131   0.157   0.108  -0.137  -0.086  -0.176   0.007   0.049  -0.030
325   I        -0.017  -0.011   0.007  -0.379  -0.369  -0.338  -0.234  -0.223  -0.194
326   A        -0.017  -0.011   0.007   0.063   0.075   0.105  -0.234  -0.223  -0.194
327   H         1.799   1.812   1.828   2.185   2.208   2.234   1.931   1.946   1.968
328   F        -0.017  -0.011   0.007   0.143   0.155   0.185  -0.234  -0.223  -0.194
329   V        -0.017  -0.011   0.007   0.250   0.263   0.293  -0.234  -0.223  -0.194
330   D        -0.017  -0.011   0.007  -0.298  -0.288  -0.257  -0.234  -0.223  -0.194
331   L         1.799   1.812   1.828   1.512   1.532   1.559   1.931   1.946   1.968
332   M        -1.080  -1.070  -1.058  -1.062  -1.056  -1.023  -0.955  -0.937  -0.914
333   D         0.131   0.080   0.077  -0.078  -0.151  -0.156   0.007  -0.074  -0.080
334   P         0.131   0.080   0.077   0.318   0.232   0.210   0.007  -0.074  -0.080
335   Y        -1.080  -1.070  -1.058  -0.591  -0.583  -0.551  -0.955  -0.937  -0.914
336   N         0.131   0.080   0.077   0.137   0.061   0.052   0.007  -0.074  -0.080
337   G         1.799   1.812   1.828   2.177   2.195   2.226   1.931   1.946   1.968
338   L         1.799   1.812   1.828   1.425   1.439   1.472   1.931   1.946   1.968
339   L         0.131   0.157   0.108  -0.224  -0.193  -0.249   0.007   0.049  -0.030
340   K         0.131   0.080   0.077   0.329   0.257   0.248   0.007  -0.074  -0.080
341   K        -1.080  -1.070  -1.058  -0.890  -0.879  -0.851  -0.955  -0.937  -0.914
342   I         0.131   0.188   0.120  -0.270  -0.190  -0.282   0.007   0.097  -0.011
343   N        -1.080  -1.070  -1.058  -0.959  -0.930  -0.920  -0.955  -0.937  -0.914
344   K        -1.080  -1.070  -1.058  -1.001  -0.979  -0.962  -0.955  -0.937  -0.914
345   I        -1.080  -1.070  -1.058  -1.253  -1.271  -1.215  -0.955  -0.937  -0.914
346   N         0.131   0.157   0.108   0.098   0.144   0.059   0.007   0.049  -0.030
347   E         0.131   0.157   0.108   0.179   0.221   0.133   0.007   0.049  -0.030
348   N        -1.080  -1.070  -1.058  -1.067  -1.046  -1.028  -0.955  -0.937  -0.914
349   L         0.131   0.157   0.108  -0.270  -0.237  -0.300   0.007   0.049  -0.030
350   S        -1.080  -1.070  -1.058  -0.954  -0.924  -0.915  -0.955  -0.937  -0.914
351   N         0.131   0.157   0.108   0.070   0.121   0.027   0.007   0.049  -0.030
352   E        -1.080  -1.070  -1.058  -1.268  -1.250  -1.230  -0.955  -0.937  -0.914
353   L        -1.080  -1.070  -1.058  -1.253  -1.219  -1.215  -0.955  -0.937  -0.914
354   Q        -1.080  -1.070  -1.058  -0.761  -0.735  -0.722  -0.955  -0.937  -0.914
355   P        -0.017  -0.011   0.007  -0.203  -0.192  -0.162  -0.234  -0.223  -0.194
356   S         1.799   1.812   1.828   1.826   1.847   1.874   1.931   1.946   1.968
357   L        -0.017  -0.011   0.007  -0.322  -0.312  -0.281  -0.234  -0.223  -0.194
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P38313
Output conservation file - output/P38313
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
