1     M         2.028   2.061   2.131   2.274   2.327   2.447   2.309   2.354   2.473
2     S        -0.083   0.006  -0.043  -0.207  -0.086  -0.144  -0.288  -0.171  -0.227
3     V        -1.230  -1.258  -1.205  -1.047  -1.070  -0.984  -0.996  -1.010  -0.934
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -0.142  -0.141  -0.112  -0.216  -0.220  -0.166  -0.347  -0.345  -0.311
7     L        -1.230  -1.244  -1.204  -1.339  -1.394  -1.300  -0.996  -0.998  -0.933
8     R         2.028   2.061   2.131   2.108   2.158   2.280   2.309   2.354   2.473
9     S        -0.747  -0.784  -0.700  -0.675  -0.742  -0.608  -0.760  -0.782  -0.675
10    T        -0.747  -0.645  -0.683  -0.962  -0.824  -0.861  -0.760  -0.643  -0.659
11    C        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    P        -0.142  -0.107  -0.083  -0.246  -0.192  -0.171  -0.347  -0.295  -0.268
16    P         0.854   0.903   0.837   1.021   1.097   0.981   0.715   0.791   0.638
17    R        -0.747  -0.758  -0.705  -0.806  -0.828  -0.746  -0.760  -0.755  -0.680
18    S        -0.565  -0.607  -0.631  -0.531  -0.623  -0.643  -0.524  -0.572  -0.589
19    L        -0.565  -0.470  -0.578  -0.549  -0.394  -0.609  -0.524  -0.401  -0.525
20    L        -0.565  -0.608  -0.634  -0.517  -0.577  -0.594  -0.524  -0.574  -0.592
21    I        -1.230  -1.104  -1.159  -1.195  -0.994  -1.105  -0.996  -0.858  -0.891
22    S        -0.747  -0.713  -0.686  -0.860  -0.805  -0.771  -0.760  -0.713  -0.662
23    F        -1.712  -1.666  -1.611  -1.458  -1.384  -1.310  -1.232  -1.178  -1.099
24    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    K        -1.712  -1.666  -1.611  -1.647  -1.566  -1.501  -1.232  -1.178  -1.099
26    R        -1.230  -1.162  -1.168  -1.108  -1.017  -1.038  -0.996  -0.918  -0.899
27    R        -0.565  -0.680  -0.690  -0.293  -0.460  -0.467  -0.524  -0.655  -0.658
28    L         0.581   0.611   0.685   0.253   0.300   0.424   0.184   0.226   0.334
29    F        -0.565  -0.680  -0.690  -0.314  -0.497  -0.500  -0.524  -0.655  -0.658
30    S         1.088   0.996   0.935   1.108   0.971   0.893   1.128   0.959   0.826
31    T         0.581   0.610   0.684   0.314   0.347   0.472   0.184   0.225   0.331
32    S        -1.230  -1.244  -1.204  -0.974  -0.990  -0.903  -0.996  -0.998  -0.933
33    R        -0.747  -0.715  -0.720  -0.795  -0.754  -0.757  -0.760  -0.715  -0.696
34    L        -1.331  -1.268  -1.231  -1.513  -1.396  -1.366  -1.090  -1.019  -0.956
35    I        -0.174  -0.188  -0.109  -0.530  -0.533  -0.419  -0.411  -0.417  -0.313
36    L         0.623   0.610   0.683   0.269   0.265   0.377   0.269   0.225   0.330
37    N        -0.753  -0.779  -0.732  -0.705  -0.774  -0.687  -0.751  -0.777  -0.706
38    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    E        -0.142  -0.149  -0.131  -0.114  -0.132  -0.120  -0.347  -0.356  -0.338
42    T        -0.142  -0.076  -0.112  -0.299  -0.205  -0.251  -0.347  -0.250  -0.311
43    T         0.854   0.925   0.843   0.937   1.054   0.914   0.715   0.832   0.649
44    K        -1.230  -1.199  -1.165  -1.258  -1.212  -1.155  -0.996  -0.956  -0.897
45    K        -0.747  -0.782  -0.700  -0.927  -0.963  -0.835  -0.760  -0.780  -0.674
46    K        -1.230  -1.103  -1.160  -1.031  -0.831  -0.928  -0.996  -0.857  -0.891
47    D        -0.565  -0.607  -0.631  -0.474  -0.547  -0.621  -0.524  -0.572  -0.589
48    K        -1.230  -1.199  -1.165  -1.298  -1.241  -1.198  -0.996  -0.956  -0.897
49    S        -0.083  -0.102  -0.070  -0.421  -0.449  -0.401  -0.288  -0.309  -0.263
50    K         2.028   2.061   2.131   1.844   1.910   2.014   2.309   2.354   2.473
51    Q        -1.712  -1.666  -1.611  -1.502  -1.455  -1.355  -1.232  -1.178  -1.099
52    Q         0.217   0.257   0.092   0.420   0.486   0.204   0.184   0.240  -0.009
53    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
57    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
58    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
59    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
60    D        -1.230  -1.258  -1.205  -1.074  -1.123  -1.057  -0.996  -1.010  -0.934
61    F        -0.565  -0.680  -0.690  -0.496  -0.720  -0.765  -0.524  -0.655  -0.658
62    N        -0.083  -0.151  -0.108  -0.108  -0.204  -0.134  -0.288  -0.373  -0.312
63    P        -0.083  -0.117  -0.097  -0.269  -0.354  -0.331  -0.288  -0.335  -0.300
64    R        -0.083  -0.118  -0.097  -0.234  -0.321  -0.297  -0.288  -0.336  -0.300
65    H         0.217   0.159   0.034   0.628   0.535   0.336   0.184   0.098  -0.095
66    L        -0.083   0.053  -0.041  -0.255  -0.027  -0.151  -0.288  -0.086  -0.214
67    G         2.028   2.061   2.131   2.216   2.270   2.389   2.309   2.354   2.473
68    V         0.700   0.663   0.706   0.454   0.371   0.431   0.420   0.331   0.377
69    A        -0.083  -0.117  -0.097  -0.039  -0.082  -0.044  -0.288  -0.335  -0.300
70    A        -0.265  -0.237  -0.164  -0.472  -0.431  -0.317  -0.524  -0.482  -0.385
71    E        -0.083  -0.034  -0.076  -0.003   0.055   0.021  -0.288  -0.233  -0.268
72    I        -1.230  -1.137  -1.190  -1.203  -1.044  -1.174  -0.996  -0.895  -0.920
73    F         0.217   0.212   0.076   0.520   0.493   0.292   0.184   0.167  -0.033
74    I         0.581   0.610   0.684   0.226   0.268   0.386   0.184   0.225   0.331
75    P         1.088   1.184   0.975   1.204   1.340   1.052   1.128   1.281   0.900
76    S         0.045   0.187   0.010   0.086   0.310   0.014  -0.071   0.140  -0.131
77    A        -0.174  -0.102  -0.126  -0.519  -0.426  -0.435  -0.411  -0.313  -0.335
78    Y        -0.083  -0.002  -0.043  -0.266  -0.142  -0.204  -0.288  -0.178  -0.227
79    K        -0.747  -0.758  -0.705  -1.022  -1.026  -0.945  -0.760  -0.755  -0.680
80    N        -1.230  -1.244  -1.204  -1.041  -1.052  -1.004  -0.996  -0.998  -0.933
81    L        -1.230  -1.258  -1.205  -1.069  -1.098  -0.988  -0.996  -1.010  -0.934
82    P         2.028   2.061   2.131   2.072   2.126   2.244   2.309   2.354   2.473
83    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
84    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
85    F        -0.565  -0.595  -0.622  -0.427  -0.467  -0.501  -0.524  -0.559  -0.578
86    A         1.088   1.202   0.984   1.232   1.390   1.093   1.128   1.310   0.917
87    H         0.217   0.212   0.076   0.335   0.302   0.152   0.184   0.167  -0.033
88    P         2.028   2.061   2.131   2.062   2.116   2.234   2.309   2.354   2.473
89    L        -0.142  -0.025  -0.088  -0.542  -0.323  -0.479  -0.347  -0.173  -0.275
90    I        -0.866  -0.807  -0.764  -0.977  -0.840  -0.826  -0.878  -0.803  -0.742
91    V        -0.565  -0.518  -0.612  -0.213  -0.164  -0.319  -0.524  -0.466  -0.566
92    A        -1.230  -1.251  -1.202  -0.988  -1.039  -0.948  -0.996  -1.004  -0.931
93    N        -0.083   0.067  -0.042  -0.314  -0.085  -0.233  -0.288  -0.075  -0.215
94    A        -1.230  -1.137  -1.190  -1.172  -1.016  -1.092  -0.996  -0.895  -0.920
95    L        -0.565  -0.584  -0.627  -0.648  -0.677  -0.752  -0.524  -0.547  -0.584
96    I        -1.230  -1.258  -1.205  -1.091  -1.116  -1.043  -0.996  -1.010  -0.934
97    R         2.028   2.061   2.131   2.108   2.158   2.280   2.309   2.354   2.473
98    R         1.088   1.184   0.975   1.193   1.335   1.014   1.128   1.281   0.900
99    L        -0.083  -0.034  -0.067  -0.141  -0.062  -0.110  -0.288  -0.239  -0.261
100   Y         0.217   0.159   0.034   0.609   0.529   0.357   0.184   0.098  -0.095
101   T        -0.747  -0.715  -0.720  -0.770  -0.749  -0.703  -0.760  -0.715  -0.696
102   F         0.700   0.808   0.794   0.541   0.738   0.686   0.420   0.615   0.553
103   G        -0.083  -0.151  -0.108  -0.042  -0.168  -0.108  -0.288  -0.373  -0.312
104   L        -0.565  -0.607  -0.631  -0.594  -0.677  -0.689  -0.524  -0.572  -0.589
105   N         2.028   2.061   2.131   2.076   2.135   2.248   2.309   2.354   2.473
106   S         1.088   1.202   0.984   1.211   1.371   1.062   1.128   1.310   0.917
107   V        -0.747  -0.729  -0.720  -0.697  -0.646  -0.646  -0.760  -0.727  -0.697
108   Q        -0.083  -0.117  -0.097  -0.067  -0.135  -0.117  -0.288  -0.335  -0.300
109   V         0.581   0.610   0.684   0.226   0.268   0.387   0.184   0.225   0.331
110   A        -0.083  -0.009  -0.071  -0.150  -0.072  -0.116  -0.288  -0.204  -0.261
111   L        -0.747  -0.715  -0.720  -1.019  -0.939  -0.952  -0.760  -0.715  -0.696
112   F         1.088   0.996   0.935   1.278   1.154   1.083   1.128   0.959   0.826
113   R         0.700   0.688   0.729   0.519   0.478   0.516   0.420   0.381   0.422
114   F        -0.747  -0.729  -0.720  -0.683  -0.685  -0.640  -0.760  -0.727  -0.697
115   Q        -0.083  -0.151  -0.108  -0.054  -0.169  -0.124  -0.288  -0.373  -0.312
116   S        -0.083  -0.048  -0.029  -0.189  -0.119  -0.092  -0.288  -0.221  -0.198
117   G         1.088   0.996   0.935   1.301   1.164   1.049   1.128   0.959   0.826
118   I        -0.747  -0.783  -0.703  -1.048  -1.115  -0.999  -0.760  -0.780  -0.678
119   K         1.088   1.066   0.955   0.975   0.964   0.793   1.128   1.083   0.862
120   P         0.700   0.688   0.729   0.501   0.462   0.503   0.420   0.381   0.422
121   S        -1.712  -1.666  -1.611  -1.361  -1.283  -1.213  -1.232  -1.178  -1.099
122   F         2.028   2.061   2.131   2.115   2.162   2.287   2.309   2.354   2.473
123   L        -0.083  -0.151  -0.108  -0.292  -0.371  -0.304  -0.288  -0.373  -0.312
124   L        -0.565  -0.680  -0.690  -0.532  -0.679  -0.684  -0.524  -0.655  -0.658
125   W         2.028   2.061   2.131   2.339   2.394   2.512   2.309   2.354   2.473
126   K         2.028   2.061   2.131   1.844   1.910   2.014   2.309   2.354   2.473
127   N         0.700   0.688   0.729   0.615   0.593   0.645   0.420   0.381   0.422
128   K         0.217   0.101   0.040   0.159   0.007  -0.092   0.184   0.012  -0.087
129   A         1.088   1.066   0.955   1.238   1.218   1.070   1.128   1.083   0.862
130   I         1.088   1.068   0.959   1.103   1.077   0.912   1.128   1.086   0.871
131   E         1.088   0.996   0.935   1.255   1.118   1.009   1.128   0.959   0.826
132   T        -0.083  -0.117  -0.097  -0.080  -0.134  -0.095  -0.288  -0.335  -0.300
133   Y         1.088   1.068   0.959   1.335   1.307   1.130   1.128   1.086   0.871
134   I         0.700   0.707   0.727   0.454   0.456   0.471   0.420   0.418   0.418
135   N        -1.230  -1.251  -1.202  -1.065  -1.113  -1.054  -0.996  -1.004  -0.931
136   V         0.217   0.159   0.034   0.267   0.185  -0.006   0.184   0.098  -0.095
137   N         2.028   2.061   2.131   2.076   2.135   2.248   2.309   2.354   2.473
138   T        -0.565  -0.355  -0.594  -0.591  -0.283  -0.621  -0.524  -0.255  -0.545
139   S        -1.230  -1.162  -1.168  -1.191  -1.095  -1.112  -0.996  -0.918  -0.899
140   F         2.028   2.061   2.131   2.115   2.162   2.287   2.309   2.354   2.473
141   A         2.028   2.061   2.131   2.079   2.134   2.251   2.309   2.354   2.473
142   H        -1.230  -1.104  -1.159  -1.056  -0.859  -0.954  -0.996  -0.858  -0.891
143   K        -0.747  -0.754  -0.704  -0.895  -0.878  -0.805  -0.760  -0.750  -0.679
144   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
145   N        -0.083  -0.014  -0.062  -0.165  -0.083  -0.121  -0.288  -0.206  -0.253
146   L        -0.565  -0.538  -0.628  -0.631  -0.585  -0.732  -0.524  -0.487  -0.585
147   S        -0.747  -0.714  -0.687  -0.716  -0.675  -0.619  -0.760  -0.713  -0.663
148   D        -1.712  -1.666  -1.611  -1.565  -1.487  -1.418  -1.232  -1.178  -1.099
149   I        -0.747  -0.785  -0.705  -0.960  -1.015  -0.894  -0.760  -0.783  -0.680
150   K         1.088   0.996   0.935   0.985   0.877   0.780   1.128   0.959   0.826
151   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
152   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
153   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
154   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
155   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
156   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
157   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
158   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
159   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
160   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
161   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
162   G        -0.747  -0.785  -0.701  -0.531  -0.566  -0.431  -0.760  -0.782  -0.676
163   L        -1.712  -1.666  -1.611  -1.716  -1.682  -1.570  -1.232  -1.178  -1.099
164   V        -0.565  -0.680  -0.690  -0.352  -0.492  -0.477  -0.524  -0.655  -0.658
165   S        -0.083  -0.151  -0.108  -0.135  -0.227  -0.149  -0.288  -0.373  -0.312
166   L        -1.712  -1.666  -1.611  -1.801  -1.703  -1.656  -1.232  -1.178  -1.099
167   W         0.217   0.159   0.034   0.699   0.621   0.440   0.184   0.098  -0.095
168   V         1.088   1.066   0.955   1.056   1.030   0.847   1.128   1.083   0.862
169   Q        -1.712  -1.666  -1.611  -1.512  -1.486  -1.365  -1.232  -1.178  -1.099
170   E         0.700   0.663   0.706   0.572   0.472   0.508   0.420   0.331   0.377
171   A         0.700   0.688   0.729   0.552   0.510   0.565   0.420   0.381   0.422
172   L         2.028   2.061   2.131   1.877   1.936   2.048   2.309   2.354   2.473
173   E        -1.712  -1.666  -1.611  -1.581  -1.553  -1.435  -1.232  -1.178  -1.099
174   A         0.217   0.101   0.040   0.401   0.233   0.141   0.184   0.012  -0.087
175   R         2.028   2.061   2.131   2.108   2.158   2.280   2.309   2.354   2.473
176   S         0.700   0.734   0.732   0.504   0.547   0.541   0.420   0.472   0.430
177   R        -0.565  -0.550  -0.629  -0.717  -0.702  -0.834  -0.524  -0.501  -0.586
178   Q        -0.083  -0.118  -0.097  -0.054  -0.124  -0.100  -0.288  -0.336  -0.300
179   L        -0.265  -0.227  -0.159  -0.562  -0.503  -0.407  -0.524  -0.470  -0.378
180   P         2.028   2.061   2.131   2.072   2.126   2.244   2.309   2.354   2.473
181   G        -1.230  -1.180  -1.170  -0.991  -0.922  -0.903  -0.996  -0.935  -0.901
182   N         0.700   0.662   0.705   0.615   0.546   0.600   0.420   0.330   0.374
183   A        -0.747  -0.651  -0.699  -0.899  -0.777  -0.821  -0.760  -0.652  -0.675
184   T         0.700   0.799   0.797   0.393   0.565   0.545   0.420   0.597   0.558
185   L         1.088   0.996   0.935   1.017   0.898   0.810   1.128   0.959   0.826
186   D         0.217   0.100   0.034   0.439   0.277   0.166   0.184   0.010  -0.095
187   W         1.088   0.996   0.935   1.498   1.378   1.296   1.128   0.959   0.826
188   Q        -0.083  -0.085  -0.047   0.040   0.064   0.117  -0.288  -0.268  -0.223
189   L         1.088   0.996   0.935   1.008   0.889   0.795   1.128   0.959   0.826
190   I        -0.083  -0.079  -0.071  -0.382  -0.370  -0.393  -0.288  -0.273  -0.265
191   K         0.217   0.100   0.034   0.138  -0.022  -0.133   0.184   0.010  -0.095
192   F         0.700   0.688   0.729   0.593   0.549   0.606   0.420   0.381   0.422
193   N        -0.565  -0.680  -0.690  -0.382  -0.563  -0.577  -0.524  -0.655  -0.658
194   A        -1.712  -1.666  -1.611  -1.587  -1.559  -1.440  -1.232  -1.178  -1.099
195   V         0.700   0.688   0.729   0.493   0.467   0.522   0.420   0.381   0.422
196   P         2.028   2.061   2.131   2.072   2.126   2.244   2.309   2.354   2.473
197   K         2.028   2.061   2.131   1.844   1.910   2.014   2.309   2.354   2.473
198   L        -0.083  -0.117  -0.097  -0.390  -0.444  -0.410  -0.288  -0.335  -0.300
199   V         0.700   0.749   0.740   0.454   0.535   0.497   0.420   0.500   0.445
200   S         0.217   0.100   0.034   0.222   0.031  -0.084   0.184   0.010  -0.095
201   V        -0.565  -0.355  -0.594  -0.428  -0.108  -0.493  -0.524  -0.255  -0.545
202   Q        -0.083  -0.151  -0.108  -0.033  -0.136  -0.079  -0.288  -0.373  -0.312
203   P        -0.747  -0.783  -0.703  -0.693  -0.731  -0.612  -0.760  -0.780  -0.678
204   I        -0.265  -0.222  -0.155  -0.458  -0.426  -0.317  -0.524  -0.462  -0.374
205   M         0.581   0.631   0.702   0.510   0.573   0.688   0.184   0.268   0.368
206   I        -0.083  -0.151  -0.108  -0.230  -0.339  -0.281  -0.288  -0.373  -0.312
207   P         0.700   0.688   0.729   0.593   0.562   0.618   0.420   0.381   0.422
208   G        -0.083  -0.151  -0.108   0.011  -0.099  -0.037  -0.288  -0.373  -0.312
209   M        -1.230  -1.251  -1.202  -0.826  -0.848  -0.760  -0.996  -1.004  -0.931
210   P        -0.083  -0.151  -0.108  -0.179  -0.293  -0.223  -0.288  -0.373  -0.312
211   L        -1.230  -1.258  -1.205  -1.272  -1.295  -1.223  -0.996  -1.010  -0.934
212   E        -0.565  -0.680  -0.690  -0.201  -0.363  -0.366  -0.524  -0.655  -0.658
213   H        -0.747  -0.783  -0.703  -0.694  -0.777  -0.653  -0.760  -0.780  -0.678
214   L        -0.747  -0.722  -0.718  -0.920  -0.871  -0.879  -0.760  -0.721  -0.695
215   Q         1.088   0.996   0.935   1.276   1.149   1.029   1.128   0.959   0.826
216   L        -0.083  -0.151  -0.108  -0.300  -0.394  -0.323  -0.288  -0.373  -0.312
217   V        -0.083   0.025  -0.038  -0.321  -0.155  -0.261  -0.288  -0.146  -0.219
218   Y         0.217   0.159   0.034   0.465   0.367   0.134   0.184   0.098  -0.095
219   K        -0.083  -0.098  -0.068  -0.276  -0.278  -0.227  -0.288  -0.303  -0.260
220   F         0.217   0.159   0.034   0.332   0.232   0.003   0.184   0.098  -0.095
221   D        -0.083  -0.009  -0.071  -0.221  -0.130  -0.205  -0.288  -0.204  -0.261
222   T         1.088   0.996   0.935   1.271   1.154   1.081   1.128   0.959   0.826
223   K         0.217   0.100   0.034   0.148  -0.009  -0.119   0.184   0.010  -0.095
224   Q         2.028   2.061   2.131   2.184   2.248   2.357   2.309   2.354   2.473
225   R         0.581   0.631   0.702   0.224   0.291   0.396   0.184   0.268   0.368
226   L        -0.083  -0.117  -0.097  -0.336  -0.386  -0.337  -0.288  -0.335  -0.300
227   I        -0.142  -0.160  -0.130  -0.404  -0.467  -0.436  -0.347  -0.379  -0.337
228   K        -0.565  -0.680  -0.690  -0.643  -0.809  -0.825  -0.524  -0.655  -0.658
229   V        -1.230  -1.137  -1.190  -1.295  -1.159  -1.255  -0.996  -0.895  -0.920
230   N        -1.230  -1.258  -1.205  -1.048  -1.084  -1.014  -0.996  -1.010  -0.934
231   Q        -0.565  -0.595  -0.622  -0.574  -0.613  -0.639  -0.524  -0.559  -0.578
232   Q        -1.712  -1.666  -1.611  -1.540  -1.465  -1.393  -1.232  -1.178  -1.099
233   T        -1.230  -1.208  -1.168  -1.153  -1.119  -1.071  -0.996  -0.964  -0.899
234   K        -0.747  -0.724  -0.684  -0.940  -0.900  -0.835  -0.760  -0.726  -0.660
235   K         0.217   0.100   0.034   0.136  -0.022  -0.137   0.184   0.010  -0.095
236   T        -0.083  -0.046  -0.030  -0.212  -0.146  -0.118  -0.288  -0.219  -0.199
237   E        -0.747  -0.695  -0.698  -0.765  -0.704  -0.691  -0.760  -0.689  -0.672
238   T        -0.747  -0.756  -0.703  -0.873  -0.855  -0.781  -0.760  -0.753  -0.679
239   L        -0.083  -0.118  -0.097  -0.253  -0.282  -0.230  -0.288  -0.336  -0.300
240   D        -0.083  -0.151  -0.108  -0.037  -0.136  -0.068  -0.288  -0.373  -0.312
241   R        -0.083  -0.151  -0.108  -0.225  -0.367  -0.307  -0.288  -0.373  -0.312
242   D        -0.083  -0.151  -0.108  -0.213  -0.351  -0.296  -0.288  -0.373  -0.312
243   V         1.088   0.996   0.935   1.076   0.942   0.847   1.128   0.959   0.826
244   V        -0.747  -0.729  -0.720  -0.757  -0.708  -0.708  -0.760  -0.727  -0.697
245   D         0.217   0.101   0.040   0.434   0.269   0.167   0.184   0.012  -0.087
246   Y         2.028   2.061   2.131   2.243   2.294   2.416   2.309   2.354   2.473
247   I        -0.083  -0.009  -0.071  -0.255  -0.182  -0.213  -0.288  -0.204  -0.261
248   A        -0.083  -0.125  -0.071  -0.150  -0.196  -0.126  -0.288  -0.332  -0.264
249   F        -0.083  -0.151  -0.108   0.075  -0.005   0.085  -0.288  -0.373  -0.312
250   L        -0.565  -0.680  -0.690  -0.658  -0.847  -0.866  -0.524  -0.655  -0.658
251   C        -0.565  -0.680  -0.690  -0.098  -0.284  -0.323  -0.524  -0.655  -0.658
252   D         0.700   0.688   0.729   0.636   0.610   0.658   0.420   0.381   0.422
253   A        -0.083  -0.151  -0.108  -0.130  -0.234  -0.168  -0.288  -0.373  -0.312
254   T        -0.565  -0.563  -0.636  -0.433  -0.440  -0.569  -0.524  -0.516  -0.595
255   T         0.217   0.100   0.034   0.409   0.235   0.133   0.184   0.010  -0.095
256   N         0.217   0.100   0.034   0.288   0.099  -0.042   0.184   0.010  -0.095
257   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
258   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
259   D        -0.083  -0.151  -0.108  -0.106  -0.221  -0.171  -0.288  -0.373  -0.312
260   M        -0.747  -0.740  -0.686  -0.644  -0.605  -0.537  -0.760  -0.741  -0.663
261   I        -0.083  -0.034  -0.022  -0.347  -0.249  -0.235  -0.288  -0.199  -0.187
262   L         2.028   2.061   2.131   1.877   1.936   2.048   2.309   2.354   2.473
263   M        -0.747  -0.729  -0.720  -0.651  -0.652  -0.613  -0.760  -0.727  -0.697
264   G         2.028   2.061   2.131   2.216   2.270   2.389   2.309   2.354   2.473
265   S         0.217   0.100   0.034   0.220   0.030  -0.087   0.184   0.010  -0.095
266   L         0.581   0.610   0.684   0.139   0.186   0.298   0.184   0.226   0.332
267   F         2.028   2.061   2.131   2.115   2.162   2.287   2.309   2.354   2.473
268   E         2.028   2.061   2.131   2.164   2.217   2.336   2.309   2.354   2.473
269   S         2.028   2.061   2.131   1.976   2.018   2.147   2.309   2.354   2.473
270   K        -0.747  -0.729  -0.720  -0.850  -0.784  -0.787  -0.760  -0.727  -0.697
271   P        -0.083  -0.151  -0.108  -0.014  -0.109  -0.039  -0.288  -0.373  -0.312
272   N        -0.565  -0.550  -0.629  -0.455  -0.441  -0.592  -0.524  -0.501  -0.586
273   D        -0.747  -0.722  -0.718  -0.711  -0.684  -0.664  -0.760  -0.721  -0.695
274   K        -0.083  -0.151  -0.108  -0.245  -0.311  -0.245  -0.288  -0.373  -0.312
275   L         1.088   1.068   0.959   0.986   0.969   0.798   1.128   1.086   0.871
276   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
277   P         2.028   2.061   2.131   2.072   2.126   2.244   2.309   2.354   2.473
278   K        -0.083  -0.151  -0.108  -0.262  -0.327  -0.259  -0.288  -0.373  -0.312
279   S        -1.712  -1.666  -1.611  -1.463  -1.394  -1.316  -1.232  -1.178  -1.099
280   Y        -0.747  -0.695  -0.698  -0.611  -0.541  -0.549  -0.760  -0.689  -0.672
281   E        -1.230  -1.244  -1.204  -0.940  -0.967  -0.908  -0.996  -0.998  -0.933
282   D        -0.747  -0.783  -0.703  -0.695  -0.761  -0.628  -0.760  -0.780  -0.678
283   D        -0.083   0.003  -0.039  -0.120   0.017  -0.055  -0.288  -0.169  -0.220
284   A        -1.712  -1.666  -1.611  -1.433  -1.362  -1.285  -1.232  -1.178  -1.099
285   K        -0.747  -0.724  -0.684  -0.762  -0.721  -0.658  -0.760  -0.726  -0.660
286   V        -0.565  -0.456  -0.575  -0.680  -0.501  -0.729  -0.524  -0.385  -0.522
287   A        -0.265  -0.225  -0.157  -0.354  -0.288  -0.196  -0.524  -0.467  -0.376
288   I        -0.565  -0.538  -0.628  -0.487  -0.441  -0.587  -0.524  -0.487  -0.585
289   H        -1.230  -1.207  -1.169  -0.915  -0.905  -0.819  -0.996  -0.963  -0.900
290   R        -0.083  -0.151  -0.108  -0.110  -0.235  -0.161  -0.288  -0.373  -0.312
291   M         0.217   0.159   0.034   0.540   0.453   0.232   0.184   0.098  -0.095
292   K         0.217   0.101   0.040   0.179   0.036  -0.061   0.184   0.012  -0.087
293   V        -1.230  -1.244  -1.204  -1.140  -1.171  -1.091  -0.996  -0.998  -0.933
294   N        -0.747  -0.786  -0.704  -0.630  -0.706  -0.569  -0.760  -0.784  -0.679
295   G         0.217   0.159   0.034   0.481   0.389   0.175   0.184   0.098  -0.095
296   D         2.028   2.061   2.131   2.122   2.179   2.294   2.309   2.354   2.473
297   I         1.088   1.184   0.975   1.085   1.225   0.911   1.128   1.281   0.900
298   Y         0.581   0.616   0.687   0.517   0.557   0.681   0.184   0.236   0.338
299   R         2.028   2.061   2.131   2.108   2.158   2.280   2.309   2.354   2.473
300   L        -1.230  -1.251  -1.202  -1.197  -1.207  -1.153  -0.996  -1.004  -0.931
301   P        -0.565  -0.563  -0.636  -0.367  -0.366  -0.472  -0.524  -0.516  -0.595
302   P         0.217   0.227   0.075   0.285   0.282   0.032   0.184   0.188  -0.033
303   S        -0.174  -0.187  -0.127  -0.528  -0.539  -0.447  -0.411  -0.418  -0.337
304   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
305   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
306   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
307   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
308   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
309   -        -0.174  -0.150  -0.103  -0.473  -0.434  -0.354  -0.411  -0.374  -0.307
310   -         0.623   0.670   0.711   0.255   0.326   0.391   0.269   0.346   0.386
311   -        -0.753  -0.749  -0.694  -0.775  -0.779  -0.700  -0.751  -0.739  -0.663
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P38300
Output conservation file - output/P38300
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
