1     -         1.772   1.778   1.792   2.081   2.090   2.113   1.899   1.906   1.925
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     M         0.118   0.079   0.069   0.222   0.157   0.117   0.003  -0.060  -0.075
4     H         0.118   0.144   0.087   0.378   0.424   0.321   0.003   0.044  -0.046
5     C         1.772   1.778   1.792   2.104   2.114   2.136   1.899   1.906   1.925
6     P         0.118   0.079   0.069   0.381   0.321   0.305   0.003  -0.060  -0.075
7     I         1.772   1.778   1.792   1.634   1.643   1.665   1.899   1.906   1.925
8     C         1.772   1.778   1.792   2.104   2.114   2.136   1.899   1.906   1.925
9     H        -1.083  -1.078  -1.068  -0.721  -0.710  -0.693  -0.946  -0.937  -0.918
10    H        -1.083  -1.078  -1.068  -0.744  -0.746  -0.716  -0.946  -0.937  -0.918
11    R        -1.083  -1.078  -1.068  -0.883  -0.867  -0.855  -0.946  -0.937  -0.918
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    A        -1.083  -1.078  -1.068  -0.813  -0.799  -0.785  -0.946  -0.937  -0.918
15    H         0.118   0.079   0.069   0.349   0.277   0.254   0.003  -0.060  -0.075
16    V         1.772   1.778   1.792   1.883   1.889   1.915   1.899   1.906   1.925
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    V         0.118   0.147   0.090   0.349   0.397   0.299   0.003   0.049  -0.042
19    Y         0.118   0.079   0.069   0.088  -0.001  -0.029   0.003  -0.060  -0.075
20    C         1.772   1.778   1.792   2.104   2.114   2.136   1.899   1.906   1.925
21    A         1.772   1.778   1.792   2.040   2.051   2.071   1.899   1.906   1.925
22    H         1.772   1.778   1.792   2.091   2.102   2.123   1.899   1.906   1.925
23    C         1.772   1.778   1.792   2.104   2.114   2.136   1.899   1.906   1.925
24    I         1.772   1.778   1.792   1.634   1.643   1.665   1.899   1.906   1.925
25    N         1.772   1.778   1.792   1.803   1.812   1.835   1.899   1.906   1.925
26    T        -1.083  -1.078  -1.068  -0.770  -0.758  -0.742  -0.946  -0.937  -0.918
27    S         1.772   1.778   1.792   1.823   1.829   1.855   1.899   1.906   1.925
28    P         1.772   1.778   1.792   2.007   2.019   2.039   1.899   1.906   1.925
29    S         0.118   0.144   0.087   0.125   0.165   0.073   0.003   0.044  -0.046
30    L         0.118   0.079   0.069  -0.339  -0.409  -0.425   0.003  -0.060  -0.075
31    L         1.772   1.778   1.792   1.438   1.445   1.469   1.899   1.906   1.925
32    L         0.118   0.144   0.087  -0.339  -0.296  -0.394   0.003   0.044  -0.046
33    K         0.118   0.147   0.090   0.082   0.136   0.024   0.003   0.049  -0.042
34    L         0.118   0.079   0.069  -0.232  -0.292  -0.301   0.003  -0.060  -0.075
35    K         1.772   1.778   1.792   1.647   1.657   1.679   1.899   1.906   1.925
36    L         0.118   0.144   0.087  -0.130  -0.097  -0.162   0.003   0.044  -0.046
37    D         0.118   0.079   0.069   0.057  -0.019  -0.041   0.003  -0.060  -0.075
38    L         1.772   1.778   1.792   1.438   1.445   1.469   1.899   1.906   1.925
39    I        -1.083  -1.078  -1.068  -1.315  -1.325  -1.288  -0.946  -0.937  -0.918
40    L         0.118   0.144   0.087  -0.339  -0.296  -0.394   0.003   0.044  -0.046
41    L         1.772   1.778   1.792   1.438   1.445   1.469   1.899   1.906   1.925
42    K        -1.083  -1.078  -1.068  -0.991  -0.980  -0.963  -0.946  -0.937  -0.918
43    D        -1.083  -1.078  -1.068  -1.119  -1.106  -1.092  -0.946  -0.937  -0.918
44    E         0.118   0.144   0.087   0.088   0.135   0.024   0.003   0.044  -0.046
45    N         0.118   0.079   0.069   0.122   0.056   0.042   0.003  -0.060  -0.075
46    K        -1.083  -1.078  -1.068  -1.136  -1.119  -1.109  -0.946  -0.937  -0.918
47    E        -1.083  -1.078  -1.068  -0.855  -0.851  -0.827  -0.946  -0.937  -0.918
48    L         1.772   1.778   1.792   1.438   1.445   1.469   1.899   1.906   1.925
49    N        -1.083  -1.078  -1.068  -1.145  -1.144  -1.117  -0.946  -0.937  -0.918
50    G        -1.083  -1.078  -1.068  -0.770  -0.753  -0.742  -0.946  -0.937  -0.918
51    K         0.118   0.079   0.069  -0.037  -0.099  -0.113   0.003  -0.060  -0.075
52    V         1.772   1.778   1.792   1.883   1.889   1.915   1.899   1.906   1.925
53    E        -0.029  -0.026  -0.012  -0.069  -0.064  -0.040  -0.234  -0.229  -0.207
54    Q         1.772   1.778   1.792   1.892   1.901   1.924   1.899   1.906   1.925
55    I        -0.029  -0.026  -0.012  -0.171  -0.167  -0.142  -0.234  -0.229  -0.207
56    L         1.772   1.778   1.792   1.440   1.447   1.471   1.899   1.906   1.925
57    N        -0.029  -0.026  -0.012  -0.102  -0.098  -0.073  -0.234  -0.229  -0.207
58    E         1.772   1.778   1.792   1.902   1.910   1.933   1.899   1.906   1.925
59    A        -0.029  -0.026  -0.012   0.064   0.070   0.093  -0.234  -0.229  -0.207
60    M        -0.029  -0.026  -0.012   0.012   0.023   0.041  -0.234  -0.229  -0.207
61    N        -0.029  -0.026  -0.012  -0.137  -0.132  -0.108  -0.234  -0.229  -0.207
62    Y        -0.029  -0.026  -0.012   0.031   0.037   0.060  -0.234  -0.229  -0.207
63    D        -0.029  -0.026  -0.012  -0.405  -0.402  -0.377  -0.234  -0.229  -0.207
64    Q        -0.029  -0.026  -0.012  -0.109  -0.105  -0.080  -0.234  -0.229  -0.207
65    L        -0.029  -0.026  -0.012  -0.255  -0.251  -0.226  -0.234  -0.229  -0.207
66    D        -0.029  -0.026  -0.012  -0.137  -0.132  -0.108  -0.234  -0.229  -0.207
67    I         1.772   1.778   1.792   1.617   1.625   1.649   1.899   1.906   1.925
68    K        -0.029  -0.026  -0.012  -0.255  -0.251  -0.226  -0.234  -0.229  -0.207
69    R        -0.029  -0.026  -0.012  -0.123  -0.118  -0.094  -0.234  -0.229  -0.207
70    M         0.118   0.147   0.090   0.410   0.462   0.366   0.003   0.049  -0.042
71    E         1.772   1.778   1.792   1.890   1.897   1.921   1.899   1.906   1.925
72    K         0.118   0.147   0.090   0.076   0.128   0.018   0.003   0.049  -0.042
73    K         0.118   0.147   0.090  -0.333  -0.284  -0.382   0.003   0.049  -0.042
74    K         0.118   0.147   0.090   0.094   0.147   0.036   0.003   0.049  -0.042
75    D        -1.083  -1.078  -1.068  -0.907  -0.889  -0.879  -0.946  -0.937  -0.918
76    P        -1.083  -1.078  -1.068  -0.820  -0.804  -0.792  -0.946  -0.937  -0.918
77    -        -0.029  -0.026  -0.012  -0.097  -0.092  -0.068  -0.234  -0.229  -0.207
78    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
79    -         1.772   1.778   1.792   2.024   2.033   2.055   1.899   1.906   1.925
80    -        -0.029  -0.026  -0.012  -0.083  -0.078  -0.054  -0.234  -0.229  -0.207
81    -        -0.029  -0.026  -0.012  -0.005   0.000   0.024  -0.234  -0.229  -0.207
82    -        -0.029  -0.026  -0.012  -0.288  -0.283  -0.259  -0.234  -0.229  -0.207
83    L         0.118   0.079   0.069  -0.130  -0.181  -0.183   0.003  -0.060  -0.075
84    M        -1.083  -1.078  -1.068  -0.895  -0.867  -0.867  -0.946  -0.937  -0.918
85    N        -1.083  -1.078  -1.068  -1.136  -1.136  -1.109  -0.946  -0.937  -0.918
86    S        -1.083  -1.078  -1.068  -0.995  -0.988  -0.967  -0.946  -0.937  -0.918
87    L         1.772   1.778   1.792   1.438   1.445   1.469   1.899   1.906   1.925
88    M        -1.083  -1.078  -1.068  -0.767  -0.758  -0.739  -0.946  -0.937  -0.918
89    K         1.772   1.778   1.792   1.647   1.657   1.679   1.899   1.906   1.925
90    L         0.118   0.144   0.087  -0.215  -0.179  -0.256   0.003   0.044  -0.046
91    D         0.118   0.144   0.087   0.159   0.200   0.107   0.003   0.044  -0.046
92    V         1.772   1.778   1.792   1.883   1.889   1.915   1.899   1.906   1.925
93    L         0.118   0.079   0.069  -0.166  -0.220  -0.225   0.003  -0.060  -0.075
94    R         0.118   0.079   0.069   0.153   0.083   0.065   0.003  -0.060  -0.075
95    M        -1.083  -1.078  -1.068  -0.991  -0.971  -0.963  -0.946  -0.937  -0.918
96    K         0.118   0.144   0.087  -0.018   0.023  -0.063   0.003   0.044  -0.046
97    K         0.118   0.147   0.090   0.082   0.136   0.024   0.003   0.049  -0.042
98    N        -1.083  -1.078  -1.068  -1.007  -0.998  -0.979  -0.946  -0.937  -0.918
99    N         0.118   0.079   0.069  -0.081  -0.167  -0.194   0.003  -0.060  -0.075
100   N         0.118   0.079   0.069   0.007  -0.068  -0.091   0.003  -0.060  -0.075
101   L         0.118   0.147   0.090  -0.232  -0.175  -0.296   0.003   0.049  -0.042
102   I         0.118   0.079   0.069  -0.245  -0.327  -0.353   0.003  -0.060  -0.075
103   R         0.118   0.144   0.087   0.082   0.130   0.019   0.003   0.044  -0.046
104   H         0.118   0.079   0.069   0.378   0.308   0.287   0.003  -0.060  -0.075
105   R         0.118   0.144   0.087   0.082   0.130   0.019   0.003   0.044  -0.046
106   I         0.118   0.079   0.069  -0.034  -0.095  -0.107   0.003  -0.060  -0.075
107   E        -1.083  -1.078  -1.068  -0.987  -0.981  -0.959  -0.946  -0.937  -0.918
108   Q         0.118   0.079   0.069  -0.018  -0.107  -0.132   0.003  -0.060  -0.075
109   L        -1.083  -1.078  -1.068  -1.227  -1.210  -1.199  -0.946  -0.937  -0.918
110   N        -1.083  -1.078  -1.068  -1.162  -1.161  -1.134  -0.946  -0.937  -0.918
111   E        -1.083  -1.078  -1.068  -0.995  -0.991  -0.967  -0.946  -0.937  -0.918
112   R         0.118   0.079   0.069   0.082   0.006  -0.017   0.003  -0.060  -0.075
113   I         1.772   1.778   1.792   1.634   1.643   1.665   1.899   1.906   1.925
114   Y        -1.083  -1.078  -1.068  -1.048  -1.038  -1.021  -0.946  -0.937  -0.918
115   S        -1.083  -1.078  -1.068  -0.979  -0.973  -0.951  -0.946  -0.937  -0.918
116   K         1.772   1.778   1.792   1.647   1.657   1.679   1.899   1.906   1.925
117   R         0.118   0.144   0.087   0.162   0.204   0.107   0.003   0.044  -0.046
118   N         0.118   0.144   0.087   0.119   0.161   0.069   0.003   0.044  -0.046
119   H        -1.083  -1.078  -1.068  -0.767  -0.764  -0.739  -0.946  -0.937  -0.918
120   I         0.118   0.079   0.069   0.014  -0.042  -0.053   0.003  -0.060  -0.075
121   S        -1.083  -1.078  -1.068  -0.895  -0.890  -0.867  -0.946  -0.937  -0.918
122   E         1.772   1.778   1.792   1.890   1.897   1.921   1.899   1.906   1.925
123   L         1.772   1.778   1.792   1.438   1.445   1.469   1.899   1.906   1.925
124   K        -1.083  -1.078  -1.068  -1.090  -1.074  -1.062  -0.946  -0.937  -0.918
125   V        -1.083  -1.078  -1.068  -0.987  -0.980  -0.959  -0.946  -0.937  -0.918
126   E        -1.083  -1.078  -1.068  -1.149  -1.127  -1.122  -0.946  -0.937  -0.918
127   I         0.118   0.079   0.069  -0.245  -0.327  -0.353   0.003  -0.060  -0.075
128   D        -0.029  -0.026  -0.012  -0.137  -0.132  -0.108  -0.234  -0.229  -0.207
129   N        -0.029  -0.026  -0.012   0.012   0.023   0.041  -0.234  -0.229  -0.207
130   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
131   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
132   Y         0.118   0.147   0.090   0.026   0.071  -0.011   0.003   0.049  -0.042
133   K        -1.083  -1.078  -1.068  -1.162  -1.146  -1.134  -0.946  -0.937  -0.918
134   C        -1.083  -1.078  -1.068  -0.817  -0.814  -0.789  -0.946  -0.937  -0.918
135   Y        -1.083  -1.078  -1.068  -0.955  -0.948  -0.927  -0.946  -0.937  -0.918
136   K        -1.083  -1.078  -1.068  -0.963  -0.935  -0.935  -0.946  -0.937  -0.918
137   V         0.118   0.147   0.090   0.349   0.397   0.299   0.003   0.049  -0.042
138   G        -1.083  -1.078  -1.068  -0.755  -0.755  -0.727  -0.946  -0.937  -0.918
139   T        -1.083  -1.078  -1.068  -0.991  -0.995  -0.963  -0.946  -0.937  -0.918
140   G        -1.083  -1.078  -1.068  -0.793  -0.792  -0.765  -0.946  -0.937  -0.918
141   T        -1.083  -1.078  -1.068  -0.979  -0.984  -0.951  -0.946  -0.937  -0.918
142   D        -1.083  -1.078  -1.068  -0.991  -0.994  -0.963  -0.946  -0.937  -0.918
143   K        -1.083  -1.078  -1.068  -1.249  -1.227  -1.221  -0.946  -0.937  -0.918
144   L         0.118   0.079   0.069  -0.130  -0.181  -0.183   0.003  -0.060  -0.075
145   R        -1.083  -1.078  -1.068  -1.115  -1.102  -1.088  -0.946  -0.937  -0.918
146   E        -1.083  -1.078  -1.068  -0.848  -0.843  -0.820  -0.946  -0.937  -0.918
147   Q         0.118   0.079   0.069   0.186   0.117   0.104   0.003  -0.060  -0.075
148   V        -1.083  -1.078  -1.068  -1.086  -1.072  -1.058  -0.946  -0.937  -0.918
149   E        -1.083  -1.078  -1.068  -1.103  -1.107  -1.075  -0.946  -0.937  -0.918
150   I        -1.083  -1.078  -1.068  -1.384  -1.358  -1.356  -0.946  -0.937  -0.918
151   S        -1.083  -1.078  -1.068  -1.040  -1.036  -1.012  -0.946  -0.937  -0.918
152   D         1.772   1.778   1.792   1.850   1.858   1.881   1.899   1.906   1.925
153   A        -0.029  -0.026  -0.012   0.071   0.076   0.100  -0.234  -0.229  -0.207
154   K        -0.029  -0.026  -0.012  -0.089  -0.084  -0.060  -0.234  -0.229  -0.207
155   N        -0.029  -0.026  -0.012  -0.474  -0.470  -0.446  -0.234  -0.229  -0.207
156   K         0.118   0.079   0.069   0.070   0.020   0.010   0.003  -0.060  -0.075
157   L         0.118   0.079   0.069  -0.140  -0.182  -0.195   0.003  -0.060  -0.075
158   A        -1.083  -1.078  -1.068  -0.883  -0.882  -0.855  -0.946  -0.937  -0.918
159   Q        -1.083  -1.078  -1.068  -1.258  -1.253  -1.230  -0.946  -0.937  -0.918
160   V        -1.083  -1.078  -1.068  -1.115  -1.132  -1.088  -0.946  -0.937  -0.918
161   S         0.118   0.144   0.087   0.032   0.077  -0.030   0.003   0.044  -0.046
162   K        -1.083  -1.078  -1.068  -1.103  -1.088  -1.075  -0.946  -0.937  -0.918
163   I        -1.083  -1.078  -1.068  -1.384  -1.358  -1.356  -0.946  -0.937  -0.918
164   C        -1.083  -1.078  -1.068  -1.111  -1.130  -1.083  -0.946  -0.937  -0.918
165   E        -1.083  -1.078  -1.068  -1.103  -1.090  -1.075  -0.946  -0.937  -0.918
166   S        -1.083  -1.078  -1.068  -0.995  -0.988  -0.967  -0.946  -0.937  -0.918
167   A        -1.083  -1.078  -1.068  -0.875  -0.881  -0.847  -0.946  -0.937  -0.918
168   R         0.118   0.079   0.069   0.183   0.115   0.100   0.003  -0.060  -0.075
169   D        -1.083  -1.078  -1.068  -0.887  -0.867  -0.859  -0.946  -0.937  -0.918
170   Y        -1.083  -1.078  -1.068  -0.790  -0.775  -0.762  -0.946  -0.937  -0.918
171   K         0.118   0.079   0.069  -0.232  -0.313  -0.340   0.003  -0.060  -0.075
172   L         0.118   0.079   0.069  -0.130  -0.181  -0.183   0.003  -0.060  -0.075
173   N        -1.083  -1.078  -1.068  -1.040  -1.041  -1.012  -0.946  -0.937  -0.918
174   L        -1.083  -1.078  -1.068  -1.115  -1.090  -1.088  -0.946  -0.937  -0.918
175   L         1.772   1.778   1.792   1.438   1.445   1.469   1.899   1.906   1.925
176   N         0.118   0.079   0.069   0.225   0.170   0.161   0.003  -0.060  -0.075
177   N        -1.083  -1.078  -1.068  -1.149  -1.134  -1.122  -0.946  -0.937  -0.918
178   W         1.772   1.778   1.792   2.161   2.171   2.193   1.899   1.906   1.925
179   F         0.118   0.144   0.087   0.393   0.434   0.342   0.003   0.044  -0.046
180   V        -1.083  -1.078  -1.068  -0.987  -0.980  -0.959  -0.946  -0.937  -0.918
181   I         1.772   1.778   1.792   1.634   1.643   1.665   1.899   1.906   1.925
182   Q        -1.083  -1.078  -1.068  -0.955  -0.947  -0.927  -0.946  -0.937  -0.918
183   K         1.772   1.778   1.792   1.647   1.657   1.679   1.899   1.906   1.925
184   L        -0.029  -0.026  -0.012  -0.216  -0.211  -0.187  -0.234  -0.229  -0.207
185   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
186   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
187   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
188   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
189   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
190   Q        -1.083  -1.078  -1.068  -1.007  -1.003  -0.979  -0.946  -0.937  -0.918
191   D         0.118   0.079   0.069   0.128   0.058   0.041   0.003  -0.060  -0.075
192   N         0.118   0.144   0.087   0.094   0.136   0.042   0.003   0.044  -0.046
193   F        -1.083  -1.078  -1.068  -0.767  -0.769  -0.739  -0.946  -0.937  -0.918
194   Q        -1.083  -1.078  -1.068  -0.975  -0.968  -0.947  -0.946  -0.937  -0.918
195   I         0.118   0.079   0.069  -0.062  -0.127  -0.140   0.003  -0.060  -0.075
196   P         0.118   0.079   0.069   0.378   0.320   0.302   0.003  -0.060  -0.075
197   F         0.118   0.079   0.069   0.393   0.326   0.311   0.003  -0.060  -0.075
198   A         0.118   0.147   0.090   0.436   0.486   0.392   0.003   0.049  -0.042
199   I         1.772   1.778   1.792   1.634   1.643   1.665   1.899   1.906   1.925
200   A        -1.083  -1.078  -1.068  -0.721  -0.702  -0.693  -0.946  -0.937  -0.918
201   F        -1.083  -1.078  -1.068  -0.691  -0.682  -0.663  -0.946  -0.937  -0.918
202   Q         0.118   0.079   0.069   0.183   0.113   0.101   0.003  -0.060  -0.075
203   P         1.772   1.778   1.792   2.007   2.019   2.039   1.899   1.906   1.925
204   L        -1.083  -1.078  -1.068  -1.119  -1.083  -1.092  -0.946  -0.937  -0.918
205   I         1.772   1.778   1.792   1.634   1.643   1.665   1.899   1.906   1.925
206   S         0.118   0.079   0.069   0.104   0.032   0.017   0.003  -0.060  -0.075
207   L         1.772   1.778   1.792   1.438   1.445   1.469   1.899   1.906   1.925
208   K         1.772   1.778   1.792   1.647   1.657   1.679   1.899   1.906   1.925
209   N         0.118   0.079   0.069   0.168   0.107   0.095   0.003  -0.060  -0.075
210   F         0.118   0.079   0.069   0.323   0.248   0.230   0.003  -0.060  -0.075
211   R         0.118   0.147   0.090   0.119   0.166   0.074   0.003   0.049  -0.042
212   I        -1.083  -1.078  -1.068  -1.098  -1.083  -1.071  -0.946  -0.937  -0.918
213   L         0.118   0.079   0.069  -0.140  -0.182  -0.195   0.003  -0.060  -0.075
214   P         0.118   0.079   0.069   0.293   0.226   0.204   0.003  -0.060  -0.075
215   L         0.118   0.079   0.069  -0.218  -0.277  -0.285   0.003  -0.060  -0.075
216   A        -1.083  -1.078  -1.068  -0.797  -0.793  -0.769  -0.946  -0.937  -0.918
217   I        -1.083  -1.078  -1.068  -1.549  -1.532  -1.522  -0.946  -0.937  -0.918
218   T        -1.083  -1.078  -1.068  -0.987  -0.977  -0.959  -0.946  -0.937  -0.918
219   N        -1.083  -1.078  -1.068  -0.991  -0.982  -0.963  -0.946  -0.937  -0.918
220   D        -1.083  -1.078  -1.068  -1.015  -1.021  -0.988  -0.946  -0.937  -0.918
221   S         1.772   1.778   1.792   1.823   1.829   1.855   1.899   1.906   1.925
222   I        -1.083  -1.078  -1.068  -1.280  -1.234  -1.252  -0.946  -0.937  -0.918
223   N         0.118   0.147   0.090   0.153   0.202   0.102   0.003   0.049  -0.042
224   I        -1.083  -1.078  -1.068  -1.183  -1.156  -1.156  -0.946  -0.937  -0.918
225   M        -1.083  -1.078  -1.068  -1.280  -1.266  -1.252  -0.946  -0.937  -0.918
226   W        -1.083  -1.078  -1.068  -0.797  -0.777  -0.769  -0.946  -0.937  -0.918
227   K         0.118   0.147   0.090   0.076   0.128   0.018   0.003   0.049  -0.042
228   Y         0.118   0.079   0.069   0.361   0.299   0.287   0.003  -0.060  -0.075
229   I         0.118   0.144   0.087   0.039   0.084   0.001   0.003   0.044  -0.046
230   S         0.118   0.147   0.090   0.094   0.142   0.046   0.003   0.049  -0.042
231   F         0.118   0.144   0.087   0.156   0.207   0.079   0.003   0.044  -0.046
232   F        -1.083  -1.078  -1.068  -1.145  -1.137  -1.117  -0.946  -0.937  -0.918
233   S        -1.083  -1.078  -1.068  -0.875  -0.860  -0.847  -0.946  -0.937  -0.918
234   D        -1.083  -1.078  -1.068  -0.887  -0.884  -0.859  -0.946  -0.937  -0.918
235   I         1.772   1.778   1.792   1.634   1.643   1.665   1.899   1.906   1.925
236   L        -1.083  -1.078  -1.068  -0.975  -0.944  -0.947  -0.946  -0.937  -0.918
237   M        -1.083  -1.078  -1.068  -0.979  -0.990  -0.951  -0.946  -0.937  -0.918
238   I         0.118   0.079   0.069   0.048  -0.005  -0.013   0.003  -0.060  -0.075
239   K         0.118   0.079   0.069  -0.018  -0.078  -0.091   0.003  -0.060  -0.075
240   L        -0.029  -0.026  -0.012  -0.297  -0.293  -0.268  -0.234  -0.229  -0.207
241   P         1.772   1.778   1.792   1.957   1.966   1.989   1.899   1.906   1.925
242   Y        -0.029  -0.026  -0.012  -0.002   0.003   0.027  -0.234  -0.229  -0.207
243   T        -0.029  -0.026  -0.012   0.155   0.161   0.184  -0.234  -0.229  -0.207
244   N        -0.029  -0.026  -0.012  -0.022  -0.010   0.007  -0.234  -0.229  -0.207
245   K        -0.029  -0.026  -0.012  -0.102  -0.098  -0.073  -0.234  -0.229  -0.207
246   I        -0.029  -0.026  -0.012  -0.227  -0.223  -0.198  -0.234  -0.229  -0.207
247   C        -0.029  -0.026  -0.012   0.225   0.231   0.254  -0.234  -0.229  -0.207
248   E         1.772   1.778   1.792   1.902   1.910   1.933   1.899   1.906   1.925
249   Q        -0.029  -0.026  -0.012  -0.075  -0.071  -0.046  -0.234  -0.229  -0.207
250   P        -0.029  -0.026  -0.012   0.005   0.010   0.034  -0.234  -0.229  -0.207
251   M         1.772   1.778   1.792   2.012   2.030   2.044   1.899   1.906   1.925
252   F        -0.029  -0.026  -0.012  -0.234  -0.230  -0.205  -0.234  -0.229  -0.207
253   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
254   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
255   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
256   -         1.772   1.778   1.792   2.024   2.033   2.055   1.899   1.906   1.925
257   -        -0.029  -0.026  -0.012  -0.069  -0.064  -0.040  -0.234  -0.229  -0.207
258   -         1.772   1.778   1.792   1.789   1.798   1.821   1.899   1.906   1.925
259   -        -0.029  -0.026  -0.012   0.016   0.021   0.045  -0.234  -0.229  -0.207
260   E        -1.083  -1.078  -1.068  -1.086  -1.073  -1.058  -0.946  -0.937  -0.918
261   F        -1.083  -1.078  -1.068  -1.145  -1.137  -1.117  -0.946  -0.937  -0.918
262   S        -1.083  -1.078  -1.068  -1.289  -1.285  -1.261  -0.946  -0.937  -0.918
263   D        -1.083  -1.078  -1.068  -0.967  -0.958  -0.939  -0.946  -0.937  -0.918
264   S         0.118   0.147   0.090   0.094   0.142   0.046   0.003   0.049  -0.042
265   I        -1.083  -1.078  -1.068  -0.995  -0.982  -0.967  -0.946  -0.937  -0.918
266   Q         0.118   0.144   0.087   0.240   0.280   0.195   0.003   0.044  -0.046
267   T        -1.083  -1.078  -1.068  -0.875  -0.874  -0.847  -0.946  -0.937  -0.918
268   V         0.118   0.144   0.087  -0.005   0.043  -0.079   0.003   0.044  -0.046
269   V        -1.083  -1.078  -1.068  -1.384  -1.378  -1.356  -0.946  -0.937  -0.918
270   Q         1.772   1.778   1.792   1.870   1.876   1.901   1.899   1.906   1.925
271   R        -1.083  -1.078  -1.068  -0.999  -0.995  -0.971  -0.946  -0.937  -0.918
272   L         0.118   0.079   0.069  -0.166  -0.220  -0.225   0.003  -0.060  -0.075
273   I         0.118   0.079   0.069  -0.062  -0.127  -0.140   0.003  -0.060  -0.075
274   K         0.118   0.079   0.069  -0.027  -0.089  -0.102   0.003  -0.060  -0.075
275   L         1.772   1.778   1.792   1.438   1.445   1.469   1.899   1.906   1.925
276   I         1.772   1.778   1.792   1.634   1.643   1.665   1.899   1.906   1.925
277   I        -1.083  -1.078  -1.068  -1.044  -1.025  -1.016  -0.946  -0.937  -0.918
278   N        -1.083  -1.078  -1.068  -0.923  -0.907  -0.895  -0.946  -0.937  -0.918
279   I         0.118   0.079   0.069   0.057   0.007  -0.002   0.003  -0.060  -0.075
280   L         1.772   1.778   1.792   1.438   1.445   1.469   1.899   1.906   1.925
281   Q        -1.083  -1.078  -1.068  -0.959  -0.952  -0.931  -0.946  -0.937  -0.918
282   I        -1.083  -1.078  -1.068  -1.384  -1.392  -1.356  -0.946  -0.937  -0.918
283   C        -1.083  -1.078  -1.068  -0.979  -0.990  -0.951  -0.946  -0.937  -0.918
284   R        -1.083  -1.078  -1.068  -0.844  -0.839  -0.816  -0.946  -0.937  -0.918
285   H        -1.083  -1.078  -1.068  -0.824  -0.821  -0.796  -0.946  -0.937  -0.918
286   L        -1.083  -1.078  -1.068  -1.262  -1.243  -1.234  -0.946  -0.937  -0.918
287   K         1.772   1.778   1.792   1.647   1.657   1.679   1.899   1.906   1.925
288   L         1.772   1.778   1.792   1.438   1.445   1.469   1.899   1.906   1.925
289   V         0.118   0.144   0.087   0.082   0.128   0.018   0.003   0.044  -0.046
290   P        -0.029  -0.026  -0.012  -0.028  -0.023   0.001  -0.234  -0.229  -0.207
291   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
292   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
293   S         0.118   0.144   0.087   0.032   0.077  -0.030   0.003   0.044  -0.046
294   T        -1.083  -1.078  -1.068  -0.836  -0.832  -0.808  -0.946  -0.937  -0.918
295   P        -1.083  -1.078  -1.068  -0.955  -0.950  -0.927  -0.946  -0.937  -0.918
296   M        -1.083  -1.078  -1.068  -1.003  -0.984  -0.975  -0.946  -0.937  -0.918
297   D         0.118   0.079   0.069   0.137   0.067   0.052   0.003  -0.060  -0.075
298   I         0.118   0.144   0.087   0.014   0.053  -0.027   0.003   0.044  -0.046
299   P        -1.083  -1.078  -1.068  -0.782  -0.776  -0.754  -0.946  -0.937  -0.918
300   W         0.118   0.079   0.069   0.433   0.360   0.338   0.003  -0.060  -0.075
301   L         0.118   0.147   0.090  -0.245  -0.188  -0.309   0.003   0.049  -0.042
302   L         1.772   1.778   1.792   1.438   1.445   1.469   1.899   1.906   1.925
303   D         0.118   0.079   0.069   0.051  -0.026  -0.048   0.003  -0.060  -0.075
304   Q         0.118   0.079   0.069   0.180   0.111   0.097   0.003  -0.060  -0.075
305   Y         1.772   1.778   1.792   1.981   1.990   2.013   1.899   1.906   1.925
306   D         1.772   1.778   1.792   1.850   1.858   1.881   1.899   1.906   1.925
307   V        -1.083  -1.078  -1.068  -1.384  -1.393  -1.356  -0.946  -0.937  -0.918
308   D         1.772   1.778   1.792   1.850   1.858   1.881   1.899   1.906   1.925
309   G         1.772   1.778   1.792   2.046   2.054   2.078   1.899   1.906   1.925
310   L         0.118   0.079   0.069  -0.140  -0.182  -0.195   0.003  -0.060  -0.075
311   F         0.118   0.079   0.069   0.240   0.159   0.134   0.003  -0.060  -0.075
312   Y         1.772   1.778   1.792   1.981   1.990   2.013   1.899   1.906   1.925
313   N        -1.083  -1.078  -1.068  -0.809  -0.797  -0.781  -0.946  -0.937  -0.918
314   M         0.118   0.079   0.069   0.137   0.063   0.018   0.003  -0.060  -0.075
315   V        -1.083  -1.078  -1.068  -0.887  -0.886  -0.859  -0.946  -0.937  -0.918
316   K         0.118   0.144   0.087   0.051   0.097   0.013   0.003   0.044  -0.046
317   R         0.118   0.147   0.090   0.137   0.182   0.091   0.003   0.049  -0.042
318   N        -1.083  -1.078  -1.068  -1.302  -1.294  -1.275  -0.946  -0.937  -0.918
319   K        -1.083  -1.078  -1.068  -0.951  -0.931  -0.923  -0.946  -0.937  -0.918
320   M        -1.083  -1.078  -1.068  -1.280  -1.280  -1.252  -0.946  -0.937  -0.918
321   K        -1.083  -1.078  -1.068  -1.149  -1.138  -1.122  -0.946  -0.937  -0.918
322   C        -1.083  -1.078  -1.068  -0.736  -0.739  -0.708  -0.946  -0.937  -0.918
323   R        -1.083  -1.078  -1.068  -1.379  -1.387  -1.352  -0.946  -0.937  -0.918
324   S         0.118   0.079   0.069   0.125   0.055   0.042   0.003  -0.060  -0.075
325   -        -0.029  -0.026  -0.012   0.002   0.007   0.031  -0.234  -0.229  -0.207
326   -         1.772   1.778   1.792   2.043   2.052   2.075   1.899   1.906   1.925
327   V        -1.083  -1.078  -1.068  -1.128  -1.119  -1.100  -0.946  -0.937  -0.918
328   S         0.118   0.147   0.090   0.094   0.142   0.046   0.003   0.049  -0.042
329   L        -1.083  -1.078  -1.068  -1.425  -1.403  -1.398  -0.946  -0.937  -0.918
330   Y         0.118   0.144   0.087   0.279   0.321   0.224   0.003   0.044  -0.046
331   W         1.772   1.778   1.792   2.156   2.166   2.188   1.899   1.906   1.925
332   T        -0.029  -0.026  -0.012   0.038   0.043   0.067  -0.234  -0.229  -0.207
333   F        -0.029  -0.026  -0.012   0.193   0.199   0.222  -0.234  -0.229  -0.207
334   G        -0.029  -0.026  -0.012   0.044   0.056   0.074  -0.234  -0.229  -0.207
335   M        -0.029  -0.026  -0.012   0.025   0.037   0.054  -0.234  -0.229  -0.207
336   L         1.772   1.778   1.792   1.440   1.447   1.471   1.899   1.906   1.925
337   Y        -0.029  -0.026  -0.012   0.044   0.050   0.074  -0.234  -0.229  -0.207
338   S        -0.029  -0.026  -0.012  -0.102  -0.098  -0.073  -0.234  -0.229  -0.207
339   M        -0.029  -0.026  -0.012  -0.157  -0.146  -0.128  -0.234  -0.229  -0.207
340   V         1.772   1.778   1.792   1.920   1.929   1.952   1.899   1.906   1.925
341   L        -0.029  -0.026  -0.012  -0.213  -0.208  -0.184  -0.234  -0.229  -0.207
342   D        -0.029  -0.026  -0.012  -0.102  -0.098  -0.073  -0.234  -0.229  -0.207
343   N        -0.029  -0.026  -0.012  -0.137  -0.132  -0.108  -0.234  -0.229  -0.207
344   M        -0.029  -0.026  -0.012  -0.283  -0.272  -0.254  -0.234  -0.229  -0.207
345   N        -0.029  -0.026  -0.012   0.012   0.023   0.041  -0.234  -0.229  -0.207
346   N        -0.029  -0.026  -0.012  -0.015  -0.010   0.014  -0.234  -0.229  -0.207
347   P        -0.029  -0.026  -0.012   0.005   0.010   0.034  -0.234  -0.229  -0.207
348   Q        -0.029  -0.026  -0.012  -0.241  -0.237  -0.212  -0.234  -0.229  -0.207
349   R        -0.029  -0.026  -0.012  -0.055  -0.050  -0.026  -0.234  -0.229  -0.207
350   G        -0.029  -0.026  -0.012   0.077   0.089   0.106  -0.234  -0.229  -0.207
351   H        -0.029  -0.026  -0.012   0.097   0.102   0.126  -0.234  -0.229  -0.207
352   P        -0.029  -0.026  -0.012  -0.326  -0.322  -0.297  -0.234  -0.229  -0.207
353   A        -0.029  -0.026  -0.012  -0.276  -0.272  -0.247  -0.234  -0.229  -0.207
354   R        -0.029  -0.026  -0.012  -0.255  -0.251  -0.226  -0.234  -0.229  -0.207
355   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
356   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
357   R        -0.029  -0.026  -0.012  -0.255  -0.251  -0.226  -0.234  -0.229  -0.207
358   T        -0.029  -0.026  -0.012  -0.123  -0.118  -0.094  -0.234  -0.229  -0.207
359   A        -0.029  -0.026  -0.012  -0.276  -0.272  -0.247  -0.234  -0.229  -0.207
360   P        -0.029  -0.026  -0.012   0.005   0.010   0.034  -0.234  -0.229  -0.207
361   P         1.772   1.778   1.792   2.007   2.019   2.039   1.899   1.906   1.925
362   P         1.772   1.778   1.792   2.007   2.019   2.039   1.899   1.906   1.925
363   T         1.772   1.778   1.792   2.072   2.083   2.104   1.899   1.906   1.925
364   V        -1.083  -1.078  -1.068  -1.240  -1.255  -1.212  -0.946  -0.937  -0.918
365   T        -1.083  -1.078  -1.068  -0.979  -0.969  -0.951  -0.946  -0.937  -0.918
366   G        -1.083  -1.078  -1.068  -1.036  -1.029  -1.008  -0.946  -0.937  -0.918
367   P        -1.083  -1.078  -1.068  -0.959  -0.964  -0.931  -0.946  -0.937  -0.918
368   H        -1.083  -1.078  -1.068  -0.955  -0.960  -0.927  -0.946  -0.937  -0.918
369   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
370   -        -0.029  -0.026  -0.012  -0.371  -0.366  -0.342  -0.234  -0.229  -0.207
371   -        -0.029  -0.026  -0.012  -0.126  -0.121  -0.097  -0.234  -0.229  -0.207
372   D         0.118   0.079   0.069   0.237   0.178   0.167   0.003  -0.060  -0.075
373   R         0.118   0.079   0.069   0.162   0.091   0.075   0.003  -0.060  -0.075
374   W         0.118   0.079   0.069   0.512   0.455   0.430   0.003  -0.060  -0.075
375   Y         0.118   0.079   0.069   0.174   0.095   0.070   0.003  -0.060  -0.075
376   V        -1.083  -1.078  -1.068  -1.020  -0.997  -0.992  -0.946  -0.937  -0.918
377   V         0.118   0.079   0.069   0.168   0.095   0.081   0.003  -0.060  -0.075
378   G         0.118   0.079   0.069   0.234   0.153   0.128   0.003  -0.060  -0.075
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P38270
Output conservation file - output/P38270
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
