1     M         0.939   0.968   1.014   1.236   1.264   1.297   0.978   1.018   1.087
2     P        -0.358  -0.247  -0.316  -0.353  -0.184  -0.377  -0.548  -0.379  -0.524
3     P         0.939   0.968   1.014   1.057   1.094   1.152   0.978   1.018   1.087
4     K         0.939   0.968   1.014   0.726   0.777   0.883   0.978   1.018   1.087
5     K         0.939   0.968   1.014   0.726   0.777   0.883   0.978   1.018   1.087
6     Q        -1.138  -0.959  -1.122  -0.994  -0.736  -1.043  -1.183  -0.950  -1.115
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     V         0.070  -0.172  -0.290   0.169  -0.140  -0.309   0.088  -0.263  -0.481
9     E        -1.860  -1.729  -1.715  -1.969  -1.799  -1.730  -1.692  -1.542  -1.432
10    E         0.070  -0.172  -0.290   0.026  -0.299  -0.492   0.088  -0.263  -0.481
11    K        -1.138  -1.319  -1.151  -1.410  -1.689  -1.413  -1.183  -1.377  -1.151
12    K        -0.358  -0.247  -0.316  -0.597  -0.425  -0.507  -0.548  -0.379  -0.524
13    V        -0.587  -0.534  -0.366  -0.953  -0.878  -0.613  -0.929  -0.851  -0.610
14    L         0.070  -0.172  -0.290   0.069  -0.215  -0.381   0.088  -0.263  -0.481
15    L         0.070  -0.172  -0.290   0.089  -0.183  -0.324   0.088  -0.263  -0.481
16    G         0.939   0.968   1.014   0.915   0.958   1.037   0.978   1.018   1.087
17    R         0.939   0.968   1.014   1.057   1.092   1.152   0.978   1.018   1.087
18    P         0.939   0.968   1.014   1.057   1.094   1.152   0.978   1.018   1.087
19    G         0.939   0.968   1.014   0.915   0.958   1.037   0.978   1.018   1.087
20    N         0.939   0.968   1.014   1.075   1.107   1.166   0.978   1.018   1.087
21    N         0.939   0.968   1.014   1.075   1.107   1.166   0.978   1.018   1.087
22    L         0.939   0.968   1.014   0.794   0.856   0.939   0.978   1.018   1.087
23    K         0.939   0.968   1.014   0.726   0.777   0.883   0.978   1.018   1.087
24    A        -1.309  -1.314  -1.135  -1.396  -1.311  -1.089  -1.438  -1.372  -1.131
25    G         0.939   0.968   1.014   0.915   0.958   1.037   0.978   1.018   1.087
26    I         0.939   0.968   1.014   0.801   0.860   0.944   0.978   1.018   1.087
27    V         0.939   0.968   1.014   0.895   0.933   1.020   0.978   1.018   1.087
28    G         0.939   0.968   1.014   0.915   0.958   1.037   0.978   1.018   1.087
29    L         0.070  -0.172  -0.290   0.083  -0.192  -0.342   0.088  -0.263  -0.481
30    A         0.070  -0.172  -0.290   0.085  -0.229  -0.397   0.088  -0.263  -0.481
31    N         0.939   0.968   1.014   1.075   1.107   1.166   0.978   1.018   1.087
32    V         0.939   0.968   1.014   0.895   0.933   1.020   0.978   1.018   1.087
33    G         0.939   0.968   1.014   0.915   0.958   1.037   0.978   1.018   1.087
34    K         0.939   0.968   1.014   0.726   0.777   0.883   0.978   1.018   1.087
35    S         0.939   0.968   1.014   1.073   1.119   1.165   0.978   1.018   1.087
36    T         0.939   0.968   1.014   1.042   1.071   1.140   0.978   1.018   1.087
37    F         0.070  -0.039  -0.282   0.343   0.188  -0.274   0.088  -0.066  -0.468
38    F         0.939   0.968   1.014   1.119   1.149   1.202   0.978   1.018   1.087
39    Q         0.070  -0.172  -0.290   0.405   0.078  -0.167   0.088  -0.263  -0.481
40    A         0.939   0.968   1.014   0.824   0.866   0.963   0.978   1.018   1.087
41    I         0.939   0.968   1.014   0.801   0.860   0.944   0.978   1.018   1.087
42    T         0.939   0.968   1.014   1.042   1.071   1.140   0.978   1.018   1.087
43    R        -0.358  -0.507  -0.363  -0.383  -0.722  -0.539  -0.548  -0.805  -0.603
44    C        -0.358  -0.394  -0.354  -0.067  -0.153  -0.197  -0.548  -0.615  -0.589
45    P        -0.758  -1.083  -1.130  -0.431  -0.906  -1.038  -0.675  -1.076  -1.124
46    L         0.939   0.968   1.014   0.794   0.856   0.939   0.978   1.018   1.087
47    G         0.939   0.968   1.014   0.915   0.958   1.037   0.978   1.018   1.087
48    N         0.939   0.968   1.014   1.075   1.107   1.166   0.978   1.018   1.087
49    P         0.939   0.968   1.014   1.057   1.094   1.152   0.978   1.018   1.087
50    A         0.939   0.968   1.014   0.824   0.866   0.963   0.978   1.018   1.087
51    N         0.939   0.968   1.014   1.075   1.107   1.166   0.978   1.018   1.087
52    Y         0.070  -0.039  -0.282   0.427   0.283  -0.119   0.088  -0.066  -0.468
53    P         0.939   0.968   1.014   1.057   1.094   1.152   0.978   1.018   1.087
54    F        -0.358  -0.507  -0.363  -0.188  -0.459  -0.268  -0.548  -0.805  -0.603
55    A         0.939   0.968   1.014   0.824   0.866   0.963   0.978   1.018   1.087
56    T         0.939   0.968   1.014   1.042   1.071   1.140   0.978   1.018   1.087
57    I         0.939   0.968   1.014   0.801   0.860   0.944   0.978   1.018   1.087
58    D        -0.358  -0.247  -0.333  -0.453  -0.273  -0.497  -0.548  -0.379  -0.554
59    P         0.939   0.968   1.014   1.057   1.094   1.152   0.978   1.018   1.087
60    E         0.939   0.968   1.014   0.788   0.838   0.933   0.978   1.018   1.087
61    E         0.939   0.968   1.014   0.788   0.838   0.933   0.978   1.018   1.087
62    A         0.939   0.968   1.014   0.824   0.866   0.963   0.978   1.018   1.087
63    R         0.070  -0.172  -0.290   0.271  -0.087  -0.362   0.088  -0.263  -0.481
64    V         0.939   0.968   1.014   0.895   0.933   1.020   0.978   1.018   1.087
65    I        -0.758  -0.894  -1.109  -0.703  -0.912  -1.211  -0.675  -0.858  -1.098
66    V         0.939   0.968   1.014   0.895   0.933   1.020   0.978   1.018   1.087
67    P         0.939   0.968   1.014   1.057   1.094   1.152   0.978   1.018   1.087
68    S        -0.358  -0.507  -0.363  -0.293  -0.577  -0.400  -0.548  -0.805  -0.603
69    P        -1.860  -1.791  -1.725  -1.764  -1.778  -1.644  -1.692  -1.623  -1.441
70    R         0.939   0.968   1.014   1.057   1.092   1.152   0.978   1.018   1.087
71    F         0.939   0.968   1.014   1.119   1.149   1.202   0.978   1.018   1.087
72    D         0.070   0.140  -0.268   0.229   0.324  -0.253   0.088   0.184  -0.446
73    K        -1.860  -1.634  -1.719  -1.852  -1.536  -1.587  -1.692  -1.500  -1.436
74    L         0.939   0.968   1.014   0.794   0.856   0.939   0.978   1.018   1.087
75    C        -1.138  -0.821  -1.111  -0.813  -0.378  -0.879  -1.183  -0.785  -1.103
76    E        -0.758  -0.516  -1.079  -0.686  -0.383  -1.108  -0.675  -0.378  -1.062
77    I        -2.260  -2.340  -2.174  -2.176  -2.373  -2.104  -1.819  -1.873  -1.617
78    Y         0.939   0.968   1.014   1.159   1.188   1.235   0.978   1.018   1.087
79    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
80    K         0.070  -0.039  -0.282   0.001  -0.117  -0.419   0.088  -0.066  -0.468
81    T         0.070   0.276  -0.263   0.315   0.555  -0.189   0.088   0.359  -0.437
82    A        -0.660  -0.522  -0.351  -1.230  -0.989  -0.680  -1.056  -0.831  -0.584
83    S         0.939   0.968   1.014   1.073   1.119   1.165   0.978   1.018   1.087
84    E        -1.460  -1.387  -1.171  -1.801  -1.654  -1.337  -1.565  -1.472  -1.173
85    V         0.939   0.968   1.014   0.895   0.933   1.020   0.978   1.018   1.087
86    P         0.939   0.968   1.014   1.057   1.094   1.152   0.978   1.018   1.087
87    A         0.939   0.968   1.014   0.824   0.866   0.963   0.978   1.018   1.087
88    H        -1.860  -1.903  -1.723  -1.387  -1.501  -1.276  -1.692  -1.712  -1.440
89    L        -0.758  -0.609  -1.087  -0.679  -0.466  -1.114  -0.675  -0.486  -1.072
90    T         0.939   0.968   1.014   1.042   1.071   1.140   0.978   1.018   1.087
91    V         0.070   0.140  -0.268   0.119   0.211  -0.411   0.088   0.184  -0.446
92    Y         0.070  -0.172  -0.290   0.427   0.100  -0.132   0.088  -0.263  -0.481
93    D         0.939   0.968   1.014   0.965   1.012   1.077   0.978   1.018   1.087
94    I         0.939   0.968   1.014   0.801   0.860   0.944   0.978   1.018   1.087
95    A         0.939   0.968   1.014   0.824   0.866   0.963   0.978   1.018   1.087
96    G         0.939   0.968   1.014   0.915   0.958   1.037   0.978   1.018   1.087
97    L         0.939   0.968   1.014   0.794   0.856   0.939   0.978   1.018   1.087
98    T         0.939   0.968   1.014   1.042   1.071   1.140   0.978   1.018   1.087
99    K         0.070  -0.039  -0.282  -0.012  -0.135  -0.456   0.088  -0.066  -0.468
100   G         0.939   0.968   1.014   0.915   0.958   1.037   0.978   1.018   1.087
101   A         0.939   0.968   1.014   0.824   0.866   0.963   0.978   1.018   1.087
102   S        -0.587  -0.472  -0.354  -0.565  -0.385  -0.241  -0.929  -0.744  -0.590
103   A        -0.358  -0.507  -0.363  -0.508  -0.767  -0.514  -0.548  -0.805  -0.603
104   G         0.939   0.968   1.014   0.915   0.958   1.037   0.978   1.018   1.087
105   E        -0.758  -1.083  -1.130  -0.741  -1.216  -1.316  -0.675  -1.076  -1.124
106   G         0.939   0.968   1.014   0.915   0.958   1.037   0.978   1.018   1.087
107   L         0.939   0.968   1.014   0.794   0.856   0.939   0.978   1.018   1.087
108   G         0.939   0.968   1.014   0.915   0.958   1.037   0.978   1.018   1.087
109   N         0.939   0.968   1.014   1.075   1.107   1.166   0.978   1.018   1.087
110   A        -0.358  -0.247  -0.316  -0.497  -0.335  -0.430  -0.548  -0.379  -0.524
111   F         0.939   0.968   1.014   1.119   1.149   1.202   0.978   1.018   1.087
112   L         0.939   0.968   1.014   0.794   0.856   0.939   0.978   1.018   1.087
113   S        -0.358  -0.247  -0.316  -0.337  -0.160  -0.366  -0.548  -0.379  -0.524
114   H        -0.587  -0.472  -0.354  -0.506  -0.328  -0.218  -0.929  -0.744  -0.590
115   I         0.070  -0.172  -0.290   0.038  -0.277  -0.483   0.088  -0.263  -0.481
116   R         0.939   0.968   1.014   1.057   1.092   1.152   0.978   1.018   1.087
117   S        -0.358  -0.100  -0.296  -0.498  -0.122  -0.400  -0.548  -0.155  -0.491
118   V         0.939   0.968   1.014   0.895   0.933   1.020   0.978   1.018   1.087
119   D         0.939   0.968   1.014   0.965   1.012   1.077   0.978   1.018   1.087
120   S        -0.660  -0.522  -0.350  -0.971  -0.766  -0.482  -1.056  -0.831  -0.583
121   I         0.939   0.968   1.014   0.801   0.860   0.944   0.978   1.018   1.087
122   Y        -0.660  -0.576  -0.366  -0.699  -0.581  -0.274  -1.056  -0.924  -0.610
123   Q         0.939   0.968   1.014   1.145   1.180   1.223   0.978   1.018   1.087
124   V         0.070   0.184  -0.263   0.183   0.317  -0.233   0.088   0.241  -0.437
125   V         0.939   0.968   1.014   0.895   0.933   1.020   0.978   1.018   1.087
126   R         0.939   0.968   1.014   1.057   1.092   1.152   0.978   1.018   1.087
127   C        -0.358  -0.507  -0.363  -0.142  -0.490  -0.346  -0.548  -0.805  -0.603
128   F         0.939   0.968   1.014   1.119   1.149   1.202   0.978   1.018   1.087
129   D         0.070   0.140  -0.268   0.188   0.287  -0.364   0.088   0.184  -0.446
130   D         0.939   0.968   1.014   0.965   1.012   1.077   0.978   1.018   1.087
131   A         0.939   0.968   1.014   0.824   0.866   0.963   0.978   1.018   1.087
132   E        -0.358  -0.247  -0.316  -0.568  -0.391  -0.506  -0.548  -0.379  -0.524
133   I         0.939   0.968   1.014   0.801   0.860   0.944   0.978   1.018   1.087
134   I         0.939   0.968   1.014   0.801   0.860   0.944   0.978   1.018   1.087
135   H         0.939   0.968   1.014   1.242   1.270   1.302   0.978   1.018   1.087
136   V        -0.587  -0.573  -0.367  -0.987  -0.971  -0.615  -0.929  -0.918  -0.611
137   E        -0.358  -0.247  -0.316  -0.532  -0.362  -0.455  -0.548  -0.379  -0.524
138   G        -0.358  -0.247  -0.316  -0.445  -0.274  -0.415  -0.548  -0.379  -0.524
139   D        -0.358  -0.247  -0.316  -0.453  -0.273  -0.459  -0.548  -0.379  -0.524
140   V         0.939   0.968   1.014   0.895   0.933   1.020   0.978   1.018   1.087
141   D        -0.587  -0.534  -0.365  -0.746  -0.668  -0.411  -0.929  -0.851  -0.607
142   P         0.939   0.968   1.014   1.057   1.094   1.152   0.978   1.018   1.087
143   V        -1.860  -1.903  -1.723  -1.915  -2.021  -1.737  -1.692  -1.712  -1.440
144   R        -0.358  -0.247  -0.316  -0.353  -0.186  -0.377  -0.548  -0.379  -0.524
145   D         0.939   0.968   1.014   0.965   1.012   1.077   0.978   1.018   1.087
146   L         0.939   0.968   1.014   0.794   0.856   0.939   0.978   1.018   1.087
147   E        -1.958  -1.936  -1.715  -2.005  -1.922  -1.556  -1.819  -1.746  -1.432
148   I         0.939   0.968   1.014   0.801   0.860   0.944   0.978   1.018   1.087
149   I         0.070   0.140  -0.268   0.038   0.148  -0.445   0.088   0.184  -0.446
150   N        -2.660  -2.557  -2.181  -2.539  -2.406  -1.851  -2.200  -2.050  -1.622
151   Q        -1.860  -1.614  -1.698  -1.725  -1.393  -1.514  -1.692  -1.396  -1.414
152   E         0.939   0.968   1.014   0.788   0.838   0.933   0.978   1.018   1.087
153   L         0.939   0.968   1.014   0.794   0.856   0.939   0.978   1.018   1.087
154   R         0.070  -0.172  -0.290   0.280  -0.067  -0.335   0.088  -0.263  -0.481
155   L         0.070  -0.172  -0.290   0.018  -0.301  -0.527   0.088  -0.263  -0.481
156   K         0.939   0.968   1.014   0.726   0.777   0.883   0.978   1.018   1.087
157   D         0.939   0.968   1.014   0.965   1.012   1.077   0.978   1.018   1.087
158   I         0.070  -0.172  -0.290   0.028  -0.295  -0.513   0.088  -0.263  -0.481
159   E         0.939   0.968   1.014   0.788   0.838   0.933   0.978   1.018   1.087
160   F         0.939   0.968   1.014   1.119   1.149   1.202   0.978   1.018   1.087
161   A        -1.460  -1.350  -1.163  -1.689  -1.571  -1.237  -1.565  -1.434  -1.164
162   Q        -2.509  -2.189  -2.157  -2.419  -1.988  -1.927  -2.073  -1.730  -1.604
163   K         0.070   0.184  -0.263  -0.014   0.135  -0.433   0.088   0.241  -0.437
164   A        -1.309  -1.146  -1.131  -1.233  -0.995  -0.952  -1.438  -1.225  -1.129
165   L         0.939   0.968   1.014   0.794   0.856   0.939   0.978   1.018   1.087
166   E         0.939   0.968   1.014   0.788   0.838   0.933   0.978   1.018   1.087
167   G        -1.538  -1.302  -1.680  -1.286  -0.996  -1.523  -1.310  -1.058  -1.397
168   A        -2.660  -2.607  -2.184  -2.822  -2.704  -2.088  -2.200  -2.083  -1.624
169   E        -1.538  -1.771  -1.716  -1.458  -1.811  -1.739  -1.310  -1.553  -1.432
170   K         0.939   0.968   1.014   0.726   0.777   0.883   0.978   1.018   1.087
171   I         0.070  -0.039  -0.282   0.014  -0.117  -0.539   0.088  -0.066  -0.468
172   A        -1.309  -1.079  -1.122  -1.451  -1.068  -1.144  -1.438  -1.124  -1.117
173   K        -1.138  -1.288  -1.147  -1.267  -1.445  -1.192  -1.183  -1.336  -1.147
174   R         0.070  -0.039  -0.282   0.330   0.195  -0.182   0.088  -0.066  -0.468
175   G         0.939   0.968   1.014   0.915   0.958   1.037   0.978   1.018   1.087
176   G         0.070  -0.172  -0.290   0.143  -0.198  -0.427   0.088  -0.263  -0.481
177   Q         0.070  -0.172  -0.290   0.407   0.081  -0.160   0.088  -0.263  -0.481
178   S         0.070  -0.172  -0.290   0.331   0.013  -0.224   0.088  -0.263  -0.481
179   L         0.070   0.184  -0.270   0.083   0.240  -0.315   0.088   0.241  -0.448
180   E         0.070  -0.039  -0.282   0.063  -0.056  -0.374   0.088  -0.066  -0.468
181   V        -0.358  -0.507  -0.363  -0.375  -0.604  -0.362  -0.548  -0.805  -0.603
182   K         0.939   0.968   1.014   0.726   0.777   0.883   0.978   1.018   1.087
183   Q         0.070  -0.172  -0.290   0.373   0.022  -0.259   0.088  -0.263  -0.481
184   K         0.070  -0.039  -0.282   0.022  -0.091  -0.362   0.088  -0.066  -0.468
185   K         0.939   0.968   1.014   0.726   0.777   0.883   0.978   1.018   1.087
186   E         0.939   0.968   1.014   0.788   0.838   0.933   0.978   1.018   1.087
187   E         0.939   0.968   1.014   0.788   0.838   0.933   0.978   1.018   1.087
188   M        -1.860  -1.929  -1.723  -1.761  -1.858  -1.547  -1.692  -1.709  -1.439
189   D        -1.309  -1.044  -1.128  -1.644  -1.250  -1.290  -1.438  -1.113  -1.125
190   L        -1.860  -1.920  -1.725  -1.882  -1.991  -1.643  -1.692  -1.727  -1.441
191   I        -1.309  -1.117  -1.136  -1.527  -1.236  -1.142  -1.438  -1.182  -1.134
192   T        -1.460  -1.190  -1.132  -1.808  -1.387  -1.299  -1.565  -1.213  -1.126
193   K         0.070   0.284  -0.262  -0.012   0.248  -0.425   0.088   0.369  -0.435
194   I        -0.358  -0.430  -0.358  -0.579  -0.706  -0.605  -0.548  -0.675  -0.596
195   I        -0.758  -1.083  -1.130  -0.688  -1.111  -1.205  -0.675  -1.076  -1.124
196   K        -1.958  -1.795  -1.716  -2.063  -1.768  -1.703  -1.819  -1.620  -1.433
197   L        -1.538  -1.739  -1.715  -1.270  -1.510  -1.386  -1.310  -1.524  -1.431
198   L         0.939   0.968   1.014   0.794   0.856   0.939   0.978   1.018   1.087
199   E        -1.138  -1.288  -1.147  -1.344  -1.550  -1.342  -1.183  -1.336  -1.147
200   S        -1.138  -1.132  -1.120  -1.090  -1.081  -1.117  -1.183  -1.136  -1.112
201   G         0.070  -0.172  -0.290   0.175  -0.145  -0.337   0.088  -0.263  -0.481
202   Q        -1.958  -1.725  -1.706  -1.930  -1.662  -1.538  -1.819  -1.537  -1.423
203   R        -0.758  -1.083  -1.130  -0.437  -0.897  -1.051  -0.675  -1.076  -1.124
204   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
205   V        -0.587  -0.557  -0.367  -0.953  -0.928  -0.617  -0.929  -0.891  -0.612
206   A        -1.138  -1.089  -1.147  -1.158  -1.166  -1.103  -1.183  -1.186  -1.147
207   N        -0.358  -0.507  -0.363  -0.365  -0.709  -0.527  -0.548  -0.805  -0.603
208   H        -1.138  -1.095  -1.147  -0.896  -0.977  -0.963  -1.183  -1.191  -1.147
209   S        -2.509  -2.396  -2.163  -2.273  -2.138  -1.852  -2.073  -1.922  -1.609
210   W         0.939   0.968   1.014   1.277   1.299   1.331   0.978   1.018   1.087
211   T        -1.138  -1.252  -1.147  -0.994  -1.183  -1.063  -1.183  -1.307  -1.146
212   S        -3.060  -2.865  -2.542  -2.728  -2.478  -2.067  -2.327  -2.129  -1.735
213   K         0.070  -0.172  -0.290  -0.012  -0.317  -0.468   0.088  -0.263  -0.481
214   E         0.939   0.968   1.014   0.788   0.838   0.933   0.978   1.018   1.087
215   V         0.070  -0.039  -0.282   0.119  -0.027  -0.438   0.088  -0.066  -0.468
216   E        -0.758  -0.569  -1.083  -0.734  -0.478  -1.221  -0.675  -0.437  -1.067
217   I        -0.587  -0.503  -0.363  -0.987  -0.840  -0.612  -0.929  -0.798  -0.604
218   I         0.939   0.968   1.014   0.801   0.860   0.944   0.978   1.018   1.087
219   N         0.939   0.968   1.014   1.075   1.107   1.166   0.978   1.018   1.087
220   S        -1.538  -1.470  -1.690  -1.129  -1.046  -1.434  -1.310  -1.228  -1.407
221   M        -0.587  -0.572  -0.367  -0.652  -0.704  -0.419  -0.929  -0.917  -0.611
222   F        -1.138  -1.082  -1.135  -0.912  -0.869  -0.997  -1.183  -1.129  -1.133
223   L         0.939   0.968   1.014   0.794   0.856   0.939   0.978   1.018   1.087
224   L         0.939   0.968   1.014   0.794   0.856   0.939   0.978   1.018   1.087
225   T         0.939   0.968   1.014   1.042   1.071   1.140   0.978   1.018   1.087
226   A         0.939   0.968   1.014   0.824   0.866   0.963   0.978   1.018   1.087
227   K         0.939   0.968   1.014   0.726   0.777   0.883   0.978   1.018   1.087
228   P         0.939   0.968   1.014   1.057   1.094   1.152   0.978   1.018   1.087
229   C        -2.660  -2.349  -2.178  -2.413  -2.063  -1.790  -2.200  -1.895  -1.621
230   I         0.070  -0.039  -0.282   0.038  -0.085  -0.469   0.088  -0.066  -0.468
231   Y         0.939   0.968   1.014   1.159   1.188   1.235   0.978   1.018   1.087
232   L         0.939   0.968   1.014   0.794   0.856   0.939   0.978   1.018   1.087
233   I        -0.587  -0.577  -0.365  -0.987  -0.977  -0.609  -0.929  -0.925  -0.607
234   N         0.939   0.968   1.014   1.075   1.107   1.166   0.978   1.018   1.087
235   L         0.070  -0.172  -0.290   0.083  -0.192  -0.342   0.088  -0.263  -0.481
236   S         0.939   0.968   1.014   1.073   1.119   1.165   0.978   1.018   1.087
237   E         0.939   0.968   1.014   0.788   0.838   0.933   0.978   1.018   1.087
238   R        -0.358  -0.221  -0.328  -0.383  -0.168  -0.448  -0.548  -0.338  -0.545
239   D         0.939   0.968   1.014   0.965   1.012   1.077   0.978   1.018   1.087
240   Y         0.070  -0.172  -0.290   0.427   0.100  -0.132   0.088  -0.263  -0.481
241   I        -1.138  -1.245  -1.137  -1.315  -1.463  -1.330  -1.183  -1.280  -1.134
242   R         0.939   0.968   1.014   1.057   1.092   1.152   0.978   1.018   1.087
243   K         0.070  -0.172  -0.290   0.001  -0.293  -0.429   0.088  -0.263  -0.481
244   K         0.939   0.968   1.014   0.726   0.777   0.883   0.978   1.018   1.087
245   N         0.939   0.968   1.014   1.075   1.107   1.166   0.978   1.018   1.087
246   K         0.939   0.968   1.014   0.726   0.777   0.883   0.978   1.018   1.087
247   H        -0.587  -0.557  -0.367  -0.464  -0.452  -0.204  -0.929  -0.891  -0.612
248   L         0.939   0.968   1.014   0.794   0.856   0.939   0.978   1.018   1.087
249   L        -0.358  -0.507  -0.363  -0.532  -0.764  -0.524  -0.548  -0.805  -0.603
250   R        -1.138  -1.023  -1.112  -1.316  -1.135  -1.256  -1.183  -0.999  -1.102
251   I         0.939   0.968   1.014   0.801   0.860   0.944   0.978   1.018   1.087
252   K         0.070  -0.039  -0.282  -0.047  -0.183  -0.554   0.088  -0.066  -0.468
253   E        -1.538  -1.739  -1.718  -1.468  -1.831  -1.762  -1.310  -1.524  -1.434
254   W         0.939   0.968   1.014   1.277   1.299   1.331   0.978   1.018   1.087
255   V        -0.587  -0.576  -0.365  -0.953  -0.974  -0.616  -0.929  -0.924  -0.608
256   D         0.070  -0.039  -0.282   0.229   0.100  -0.276   0.088  -0.066  -0.468
257   K        -1.958  -1.725  -1.707  -2.274  -1.886  -1.800  -1.819  -1.537  -1.424
258   Y        -1.558  -1.432  -1.161  -1.441  -1.267  -0.893  -1.692  -1.515  -1.161
259   S         0.070  -0.039  -0.282   0.301   0.159  -0.296   0.088  -0.066  -0.468
260   P         0.070  -0.039  -0.282   0.271   0.118  -0.346   0.088  -0.066  -0.468
261   G         0.939   0.968   1.014   0.915   0.958   1.037   0.978   1.018   1.087
262   D         0.939   0.968   1.014   0.965   1.012   1.077   0.978   1.018   1.087
263   L        -1.538  -1.739  -1.718  -1.401  -1.679  -1.638  -1.310  -1.524  -1.434
264   I         0.070  -0.172  -0.290   0.024  -0.297  -0.525   0.088  -0.263  -0.481
265   I        -0.358  -0.247  -0.316  -0.579  -0.394  -0.529  -0.548  -0.379  -0.524
266   P         0.939   0.968   1.014   1.057   1.094   1.152   0.978   1.018   1.087
267   F        -1.860  -1.946  -1.727  -1.672  -1.810  -1.561  -1.692  -1.747  -1.442
268   S         0.939   0.968   1.014   1.073   1.119   1.165   0.978   1.018   1.087
269   V         0.939   0.968   1.014   0.895   0.933   1.020   0.978   1.018   1.087
270   S        -1.138  -1.179  -1.131  -0.906  -0.985  -0.961  -1.183  -1.196  -1.127
271   L        -0.358  -0.507  -0.363  -0.511  -0.733  -0.489  -0.548  -0.805  -0.603
272   E         0.939   0.968   1.014   0.788   0.838   0.933   0.978   1.018   1.087
273   E         0.939   0.968   1.014   0.788   0.838   0.933   0.978   1.018   1.087
274   R        -0.587  -0.573  -0.367  -0.964  -0.923  -0.556  -0.929  -0.918  -0.611
275   L         0.939   0.968   1.014   0.794   0.856   0.939   0.978   1.018   1.087
276   S        -1.460  -1.429  -1.170  -1.518  -1.502  -1.145  -1.565  -1.516  -1.172
277   H        -1.860  -1.903  -1.723  -1.460  -1.581  -1.386  -1.692  -1.712  -1.440
278   M        -0.358  -0.507  -0.363  -0.089  -0.381  -0.217  -0.548  -0.805  -0.603
279   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
280   S        -0.587  -0.390  -0.338  -0.680  -0.360  -0.318  -0.929  -0.608  -0.562
281   P        -1.860  -1.478  -1.693  -1.940  -1.416  -1.677  -1.692  -1.281  -1.410
282   E        -0.758  -0.813  -1.100  -0.729  -0.807  -1.237  -0.675  -0.741  -1.087
283   D         0.070   0.276  -0.263   0.036   0.292  -0.417   0.088   0.359  -0.437
284   A        -1.138  -0.873  -1.112  -1.205  -0.853  -1.155  -1.183  -0.860  -1.102
285   E        -1.538  -1.771  -1.716  -1.491  -1.878  -1.807  -1.310  -1.553  -1.432
286   E        -0.587  -0.472  -0.354  -1.037  -0.835  -0.645  -0.929  -0.744  -0.590
287   E        -0.587  -0.472  -0.354  -0.854  -0.673  -0.465  -0.929  -0.744  -0.590
288   L        -0.660  -0.522  -0.351  -0.841  -0.531  -0.323  -1.056  -0.831  -0.584
289   K         0.939   0.968   1.014   0.726   0.777   0.883   0.978   1.018   1.087
290   K        -1.958  -1.619  -1.708  -2.181  -1.767  -1.682  -1.819  -1.479  -1.426
291   L        -1.138  -1.122  -1.129  -1.338  -1.272  -1.328  -1.183  -1.129  -1.125
292   Q        -0.758  -0.812  -1.102  -0.529  -0.635  -0.988  -0.675  -0.770  -1.090
293   T        -1.309  -1.100  -1.138  -1.497  -1.234  -1.197  -1.438  -1.204  -1.137
294   I        -2.509  -2.459  -2.178  -2.326  -2.351  -2.002  -2.073  -1.981  -1.620
295   S         0.070   0.184  -0.270   0.331   0.476  -0.190   0.088   0.241  -0.448
296   A        -0.758  -0.894  -1.109  -0.604  -0.776  -1.020  -0.675  -0.858  -1.098
297   L         0.939   0.968   1.014   0.794   0.856   0.939   0.978   1.018   1.087
298   P         0.939   0.968   1.014   1.057   1.094   1.152   0.978   1.018   1.087
299   K         0.939   0.968   1.014   0.726   0.777   0.883   0.978   1.018   1.087
300   I         0.939   0.968   1.014   0.801   0.860   0.944   0.978   1.018   1.087
301   I         0.070   0.285  -0.262   0.038   0.316  -0.434   0.088   0.371  -0.435
302   T        -1.309  -1.322  -1.146  -1.427  -1.469  -1.207  -1.438  -1.407  -1.146
303   T        -1.538  -1.505  -1.697  -1.148  -1.119  -1.445  -1.310  -1.264  -1.413
304   M         0.070  -0.172  -0.290   0.476   0.126  -0.157   0.088  -0.263  -0.481
305   R         0.070  -0.172  -0.290   0.332   0.017  -0.188   0.088  -0.263  -0.481
306   Q        -1.538  -1.663  -1.713  -1.134  -1.374  -1.580  -1.310  -1.456  -1.428
307   K        -1.138  -1.164  -1.151  -1.366  -1.481  -1.331  -1.183  -1.253  -1.151
308   L         0.939   0.968   1.014   0.794   0.856   0.939   0.978   1.018   1.087
309   D        -1.138  -1.164  -1.151  -1.065  -1.155  -1.112  -1.183  -1.253  -1.151
310   L         0.939   0.968   1.014   0.794   0.856   0.939   0.978   1.018   1.087
311   I         0.070  -0.039  -0.282   0.041  -0.080  -0.461   0.088  -0.066  -0.468
312   S         0.070  -0.172  -0.290   0.336   0.022  -0.211   0.088  -0.263  -0.481
313   F         0.070  -0.172  -0.290   0.393   0.072  -0.144   0.088  -0.263  -0.481
314   F         0.939   0.968   1.014   1.119   1.149   1.202   0.978   1.018   1.087
315   T         0.939   0.968   1.014   1.042   1.071   1.140   0.978   1.018   1.087
316   C        -1.860  -1.788  -1.718  -1.467  -1.378  -1.361  -1.692  -1.581  -1.434
317   G         0.939   0.968   1.014   0.915   0.958   1.037   0.978   1.018   1.087
318   P        -0.758  -0.894  -1.109  -0.489  -0.723  -1.139  -0.675  -0.858  -1.098
319   D         0.939   0.968   1.014   0.965   1.012   1.077   0.978   1.018   1.087
320   E         0.939   0.968   1.014   0.788   0.838   0.933   0.978   1.018   1.087
321   V         0.939   0.968   1.014   0.895   0.933   1.020   0.978   1.018   1.087
322   R         0.939   0.968   1.014   1.057   1.092   1.152   0.978   1.018   1.087
323   E        -0.758  -1.083  -1.130  -0.655  -1.070  -1.104  -0.675  -1.076  -1.124
324   W         0.939   0.968   1.014   1.277   1.299   1.331   0.978   1.018   1.087
325   T         0.939   0.968   1.014   1.042   1.071   1.140   0.978   1.018   1.087
326   I         0.939   0.968   1.014   0.801   0.860   0.944   0.978   1.018   1.087
327   R         0.939   0.968   1.014   1.057   1.092   1.152   0.978   1.018   1.087
328   R        -1.558  -1.473  -1.174  -1.730  -1.649  -1.202  -1.692  -1.564  -1.176
329   G        -0.358  -0.247  -0.316  -0.342  -0.187  -0.275  -0.548  -0.379  -0.524
330   T        -0.358  -0.247  -0.316  -0.260  -0.112  -0.241  -0.548  -0.379  -0.524
331   K        -0.358  -0.247  -0.316  -0.602  -0.432  -0.514  -0.548  -0.379  -0.524
332   A         0.939   0.968   1.014   0.824   0.866   0.963   0.978   1.018   1.087
333   P         0.939   0.968   1.014   1.057   1.094   1.152   0.978   1.018   1.087
334   Q         0.939   0.968   1.014   1.145   1.180   1.223   0.978   1.018   1.087
335   A         0.939   0.968   1.014   0.824   0.866   0.963   0.978   1.018   1.087
336   A         0.939   0.968   1.014   0.824   0.866   0.963   0.978   1.018   1.087
337   G         0.939   0.968   1.014   0.915   0.958   1.037   0.978   1.018   1.087
338   V        -0.358  -0.247  -0.316  -0.439  -0.280  -0.395  -0.548  -0.379  -0.524
339   I         0.939   0.968   1.014   0.801   0.860   0.944   0.978   1.018   1.087
340   H         0.939   0.968   1.014   1.242   1.270   1.302   0.978   1.018   1.087
341   N        -0.660  -0.522  -0.351  -0.813  -0.597  -0.339  -1.056  -0.831  -0.584
342   D         0.939   0.968   1.014   0.965   1.012   1.077   0.978   1.018   1.087
343   L        -0.358  -0.507  -0.363  -0.511  -0.733  -0.489  -0.548  -0.805  -0.603
344   M        -0.660  -0.522  -0.351  -0.874  -0.706  -0.420  -1.056  -0.831  -0.584
345   N        -1.460  -1.429  -1.170  -1.550  -1.611  -1.205  -1.565  -1.516  -1.172
346   T         0.070  -0.172  -0.290   0.270  -0.086  -0.334   0.088  -0.263  -0.481
347   F         0.939   0.968   1.014   1.119   1.149   1.202   0.978   1.018   1.087
348   I         0.070  -0.172  -0.290   0.038  -0.277  -0.483   0.088  -0.263  -0.481
349   L        -0.758  -1.083  -1.130  -0.680  -1.114  -1.174  -0.675  -1.076  -1.124
350   A         0.070  -0.172  -0.290   0.064  -0.265  -0.457   0.088  -0.263  -0.481
351   Q        -0.758  -1.083  -1.130  -0.390  -0.897  -1.096  -0.675  -1.076  -1.124
352   V         0.070  -0.172  -0.290   0.119  -0.224  -0.452   0.088  -0.263  -0.481
353   M        -1.860  -1.788  -1.718  -1.531  -1.424  -1.397  -1.692  -1.581  -1.434
354   K        -0.758  -1.083  -1.130  -0.699  -1.096  -1.099  -0.675  -1.076  -1.124
355   C         0.070   0.276  -0.263   0.449   0.672  -0.028   0.088   0.359  -0.437
356   E        -2.509  -2.478  -2.184  -2.396  -2.309  -1.855  -2.073  -2.000  -1.624
357   D         0.070  -0.039  -0.282   0.203   0.066  -0.348   0.088  -0.066  -0.468
358   V        -0.587  -0.347  -0.318  -0.993  -0.564  -0.537  -0.929  -0.539  -0.527
359   F        -2.109  -2.042  -1.733  -2.206  -2.054  -1.603  -1.946  -1.829  -1.448
360   E         0.070  -0.172  -0.290   0.036  -0.278  -0.462   0.088  -0.263  -0.481
361   Y        -0.358  -0.354  -0.351  -0.263  -0.284  -0.401  -0.548  -0.550  -0.583
362   K        -0.660  -0.576  -0.366  -1.160  -1.013  -0.644  -1.056  -0.924  -0.610
363   D        -0.758  -1.083  -1.130  -0.524  -0.979  -1.100  -0.675  -1.076  -1.124
364   D        -0.587  -0.562  -0.367  -0.897  -0.889  -0.581  -0.929  -0.900  -0.612
365   S        -2.260  -2.083  -2.148  -1.948  -1.750  -1.964  -1.819  -1.630  -1.597
366   A        -0.587  -0.472  -0.354  -0.870  -0.683  -0.488  -0.929  -0.744  -0.590
367   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
368   I        -1.309  -1.314  -1.135  -1.508  -1.392  -1.117  -1.438  -1.372  -1.131
369   K        -1.138  -1.144  -1.141  -1.252  -1.274  -1.156  -1.183  -1.205  -1.141
370   A         0.939   0.968   1.014   0.824   0.866   0.963   0.978   1.018   1.087
371   A         0.070  -0.039  -0.282   0.037  -0.111  -0.521   0.088  -0.066  -0.468
372   G         0.939   0.968   1.014   0.915   0.958   1.037   0.978   1.018   1.087
373   K         0.939   0.968   1.014   0.726   0.777   0.883   0.978   1.018   1.087
374   L        -0.758  -1.083  -1.130  -0.677  -1.095  -1.168  -0.675  -1.076  -1.124
375   M        -1.460  -1.336  -1.161  -1.348  -1.204  -1.016  -1.565  -1.402  -1.161
376   Q        -0.358  -0.507  -0.363  -0.200  -0.493  -0.314  -0.548  -0.805  -0.603
377   K         0.939   0.968   1.014   0.726   0.777   0.883   0.978   1.018   1.087
378   G         0.939   0.968   1.014   0.915   0.958   1.037   0.978   1.018   1.087
379   K         0.939   0.968   1.014   0.726   0.777   0.883   0.978   1.018   1.087
380   D        -0.358  -0.393  -0.353  -0.453  -0.533  -0.542  -0.548  -0.614  -0.588
381   Y         0.939   0.968   1.014   1.159   1.188   1.235   0.978   1.018   1.087
382   V        -0.358  -0.247  -0.316  -0.414  -0.256  -0.360  -0.548  -0.379  -0.524
383   V         0.070  -0.172  -0.290   0.183  -0.117  -0.271   0.088  -0.263  -0.481
384   E         0.939   0.968   1.014   0.788   0.838   0.933   0.978   1.018   1.087
385   D         0.070  -0.172  -0.290   0.228  -0.080  -0.289   0.088  -0.263  -0.481
386   G         0.939   0.968   1.014   0.915   0.958   1.037   0.978   1.018   1.087
387   D         0.939   0.968   1.014   0.965   1.012   1.077   0.978   1.018   1.087
388   I        -0.358  -0.161  -0.320  -0.579  -0.261  -0.536  -0.548  -0.247  -0.531
389   I         0.070  -0.172  -0.290   0.028  -0.295  -0.513   0.088  -0.263  -0.481
390   Y        -1.538  -1.771  -1.716  -1.014  -1.370  -1.367  -1.310  -1.553  -1.432
391   F        -1.138  -1.245  -1.138  -0.920  -1.046  -0.941  -1.183  -1.280  -1.134
392   R        -0.660  -0.522  -0.351  -1.053  -0.857  -0.555  -1.056  -0.831  -0.584
393   A         0.939   0.968   1.014   0.824   0.866   0.963   0.978   1.018   1.087
394   G        -0.358  -0.247  -0.316  -0.490  -0.318  -0.479  -0.548  -0.379  -0.524
395   A        -0.441  -0.366  -0.342  -0.673  -0.562  -0.527  -0.683  -0.569  -0.568
396   G        -0.007  -0.255  -0.321   0.041  -0.337  -0.490  -0.018  -0.391  -0.533
397   K         0.939   0.968   1.014   0.726   0.777   0.883   0.978   1.018   1.087
398   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
399   N        -1.309  -1.322  -1.146  -1.249  -1.253  -0.995  -1.438  -1.407  -1.146
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P38219
Output conservation file - output/P38219
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
