1     M         1.211   1.211   1.237   1.541   1.538   1.568   1.279   1.280   1.314
2     S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    L        -0.181  -0.226  -0.207  -0.427  -0.486  -0.429  -0.353  -0.427  -0.401
17    H         1.211   1.211   1.237   1.406   1.406   1.439   1.279   1.280   1.314
18    P        -0.305  -0.298  -0.236  -0.559  -0.539  -0.433  -0.557  -0.545  -0.449
19    K        -0.019  -0.029  -0.151  -0.291  -0.307  -0.500  -0.098  -0.114  -0.310
20    T        -1.063  -1.092  -1.084  -0.935  -0.982  -0.966  -1.016  -1.051  -1.022
21    T         1.211   1.211   1.237   1.300   1.300   1.338   1.279   1.280   1.314
22    E         1.211   1.211   1.237   1.147   1.144   1.191   1.279   1.280   1.314
23    I        -0.019   0.021  -0.137  -0.013   0.050  -0.206  -0.098  -0.037  -0.287
24    Y        -0.019   0.012  -0.139   0.093   0.143  -0.114  -0.098  -0.051  -0.291
25    F         1.211   1.211   1.237   1.407   1.404   1.440   1.279   1.280   1.314
26    S        -1.820  -1.809  -1.713  -1.725  -1.697  -1.556  -1.475  -1.463  -1.336
27    L        -0.019  -0.061  -0.158  -0.188  -0.244  -0.355  -0.098  -0.163  -0.320
28    N         1.211   1.211   1.237   1.322   1.319   1.358   1.279   1.280   1.314
29    N        -0.019   0.021  -0.137   0.106   0.166  -0.099  -0.098  -0.037  -0.287
30    G         1.211   1.211   1.237   1.235   1.236   1.275   1.279   1.280   1.314
31    V        -1.820  -1.809  -1.713  -1.651  -1.634  -1.485  -1.475  -1.463  -1.336
32    R        -1.063  -1.048  -1.052  -1.051  -1.027  -1.011  -1.016  -0.998  -0.985
33    I        -0.019  -0.061  -0.158  -0.013  -0.078  -0.242  -0.098  -0.163  -0.320
34    P         1.211   1.211   1.237   1.231   1.232   1.271   1.279   1.280   1.314
35    A         1.211   1.211   1.237   1.274   1.272   1.313   1.279   1.280   1.314
36    L        -0.019  -0.061  -0.158  -0.188  -0.244  -0.355  -0.098  -0.163  -0.320
37    G         1.211   1.211   1.237   1.235   1.236   1.275   1.279   1.280   1.314
38    L         1.211   1.211   1.237   0.953   0.953   1.005   1.279   1.280   1.314
39    G         1.211   1.211   1.237   1.235   1.236   1.275   1.279   1.280   1.314
40    T         1.211   1.211   1.237   1.300   1.300   1.338   1.279   1.280   1.314
41    A        -0.305  -0.298  -0.236  -0.449  -0.436  -0.330  -0.557  -0.545  -0.449
42    N        -1.063  -1.042  -1.047  -0.959  -0.926  -0.936  -1.016  -0.990  -0.979
43    P        -1.063  -1.068  -1.054  -0.937  -0.941  -0.912  -1.016  -1.022  -0.986
44    H        -1.063  -1.014  -1.071  -0.955  -0.868  -1.014  -1.016  -0.957  -1.007
45    E        -0.305  -0.298  -0.236  -0.539  -0.528  -0.420  -0.557  -0.545  -0.449
46    K        -1.820  -1.809  -1.713  -1.672  -1.653  -1.506  -1.475  -1.463  -1.336
47    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
48    A        -0.019   0.012  -0.139   0.025   0.072  -0.194  -0.098  -0.051  -0.291
49    E        -0.019   0.012  -0.139  -0.063  -0.018  -0.254  -0.098  -0.051  -0.291
50    T        -0.305  -0.298  -0.236  -0.430  -0.414  -0.312  -0.557  -0.545  -0.449
51    K         1.211   1.211   1.237   1.107   1.108   1.153   1.279   1.280   1.314
52    Q        -0.305  -0.298  -0.236  -0.368  -0.347  -0.249  -0.557  -0.545  -0.449
53    A        -0.305  -0.298  -0.236  -0.327  -0.320  -0.219  -0.557  -0.545  -0.449
54    V         1.211   1.211   1.237   1.213   1.212   1.254   1.279   1.280   1.314
55    K        -0.305  -0.298  -0.236  -0.582  -0.570  -0.462  -0.557  -0.545  -0.449
56    A        -0.305  -0.298  -0.236  -0.386  -0.375  -0.273  -0.557  -0.545  -0.449
57    A         1.211   1.211   1.237   1.274   1.272   1.313   1.279   1.280   1.314
58    I        -0.305  -0.298  -0.236  -0.504  -0.490  -0.385  -0.557  -0.545  -0.449
59    K        -0.019   0.021  -0.137  -0.052   0.006  -0.213  -0.098  -0.037  -0.287
60    A         1.211   1.211   1.237   1.274   1.272   1.313   1.279   1.280   1.314
61    G         1.211   1.211   1.237   1.235   1.236   1.275   1.279   1.280   1.314
62    Y         1.211   1.211   1.237   1.309   1.310   1.346   1.279   1.280   1.314
63    R         1.211   1.211   1.237   1.369   1.367   1.403   1.279   1.280   1.314
64    H         1.211   1.211   1.237   1.424   1.421   1.456   1.279   1.280   1.314
65    I         1.211   1.211   1.237   1.200   1.202   1.242   1.279   1.280   1.314
66    D         1.211   1.211   1.237   1.218   1.220   1.259   1.279   1.280   1.314
67    T         1.211   1.211   1.237   1.300   1.300   1.338   1.279   1.280   1.314
68    A         1.211   1.211   1.237   1.274   1.272   1.313   1.279   1.280   1.314
69    W         1.211   1.211   1.237   1.478   1.478   1.508   1.279   1.280   1.314
70    A        -1.063  -1.014  -1.071  -0.890  -0.819  -0.892  -1.016  -0.957  -1.007
71    Y         1.211   1.211   1.237   1.309   1.310   1.346   1.279   1.280   1.314
72    E        -0.019  -0.029  -0.151  -0.001  -0.017  -0.232  -0.098  -0.114  -0.310
73    T        -0.019  -0.061  -0.158   0.084   0.016  -0.157  -0.098  -0.163  -0.320
74    E         1.211   1.211   1.237   1.147   1.144   1.191   1.279   1.280   1.314
75    P        -1.063  -1.068  -1.054  -1.125  -1.135  -1.125  -1.016  -1.022  -0.986
76    F        -0.019  -0.029  -0.151   0.154   0.140  -0.046  -0.098  -0.114  -0.310
77    V        -0.305  -0.298  -0.236  -0.504  -0.489  -0.384  -0.557  -0.545  -0.449
78    G         1.211   1.211   1.237   1.235   1.236   1.275   1.279   1.280   1.314
79    E         1.211   1.211   1.237   1.147   1.144   1.191   1.279   1.280   1.314
80    A         1.211   1.211   1.237   1.274   1.272   1.313   1.279   1.280   1.314
81    I        -0.019  -0.029  -0.151  -0.259  -0.273  -0.453  -0.098  -0.114  -0.310
82    K        -0.305  -0.300  -0.238  -0.446  -0.434  -0.330  -0.557  -0.550  -0.452
83    E        -0.019   0.021  -0.137  -0.065  -0.007  -0.252  -0.098  -0.037  -0.287
84    L         1.211   1.211   1.237   0.953   0.953   1.005   1.279   1.280   1.314
85    L        -0.019  -0.029  -0.151   0.107   0.086  -0.172  -0.098  -0.114  -0.310
86    E        -0.305  -0.298  -0.236  -0.497  -0.492  -0.382  -0.557  -0.545  -0.449
87    D        -0.019  -0.029  -0.151  -0.063  -0.081  -0.275  -0.098  -0.114  -0.310
88    G        -0.019  -0.061  -0.158   0.071   0.011  -0.136  -0.098  -0.163  -0.320
89    S        -1.191  -1.177  -1.101  -1.223  -1.208  -1.076  -1.169  -1.151  -1.041
90    I        -1.063  -1.062  -1.056  -1.035  -1.035  -1.019  -1.016  -1.015  -0.989
91    K         1.211   1.211   1.237   1.107   1.108   1.153   1.279   1.280   1.314
92    R         1.211   1.211   1.237   1.369   1.367   1.403   1.279   1.280   1.314
93    E         1.211   1.211   1.237   1.147   1.144   1.191   1.279   1.280   1.314
94    D         1.211   1.211   1.237   1.218   1.220   1.259   1.279   1.280   1.314
95    L         1.211   1.211   1.237   0.953   0.953   1.005   1.279   1.280   1.314
96    F        -0.019  -0.061  -0.158   0.252   0.188   0.034  -0.098  -0.163  -0.320
97    I         1.211   1.211   1.237   1.200   1.202   1.242   1.279   1.280   1.314
98    T         1.211   1.211   1.237   1.300   1.300   1.338   1.279   1.280   1.314
99    T        -0.305  -0.301  -0.238  -0.361  -0.354  -0.252  -0.557  -0.550  -0.453
100   K         1.211   1.211   1.237   1.107   1.108   1.153   1.279   1.280   1.314
101   V        -0.019   0.012  -0.139   0.063   0.105  -0.108  -0.098  -0.051  -0.291
102   W         1.211   1.211   1.237   1.478   1.478   1.508   1.279   1.280   1.314
103   P        -0.019  -0.061  -0.158   0.085   0.026  -0.113  -0.098  -0.163  -0.320
104   V        -1.063  -1.092  -1.084  -0.946  -0.995  -0.992  -1.016  -1.051  -1.022
105   L        -1.820  -1.809  -1.713  -1.568  -1.547  -1.406  -1.475  -1.463  -1.336
106   W        -0.019   0.021  -0.137   0.320   0.377   0.127  -0.098  -0.037  -0.287
107   D        -1.820  -1.809  -1.713  -1.561  -1.547  -1.399  -1.475  -1.463  -1.336
108   E        -1.820  -1.809  -1.713  -1.691  -1.680  -1.524  -1.475  -1.463  -1.336
109   V        -0.305  -0.298  -0.236  -0.481  -0.468  -0.363  -0.557  -0.545  -0.449
110   D        -0.305  -0.298  -0.236  -0.539  -0.523  -0.416  -0.557  -0.545  -0.449
111   R        -0.019  -0.029  -0.151  -0.052  -0.066  -0.235  -0.098  -0.114  -0.310
112   S         1.211   1.211   1.237   1.309   1.308   1.346   1.279   1.280   1.314
113   L         1.211   1.211   1.237   0.953   0.953   1.005   1.279   1.280   1.314
114   N        -0.305  -0.298  -0.236  -0.411  -0.394  -0.293  -0.557  -0.545  -0.449
115   E        -0.019   0.021  -0.137  -0.100  -0.038  -0.302  -0.098  -0.037  -0.287
116   S         1.211   1.211   1.237   1.309   1.308   1.346   1.279   1.280   1.314
117   L         1.211   1.211   1.237   0.953   0.953   1.005   1.279   1.280   1.314
118   K        -1.063  -1.062  -1.056  -1.089  -1.088  -1.058  -1.016  -1.015  -0.989
119   A        -1.063  -1.068  -1.054  -0.944  -0.949  -0.930  -1.016  -1.022  -0.986
120   L         1.211   1.211   1.237   0.953   0.953   1.005   1.279   1.280   1.314
121   G        -1.063  -1.068  -1.054  -1.018  -1.032  -1.005  -1.016  -1.022  -0.986
122   L        -1.063  -1.062  -1.056  -1.302  -1.298  -1.263  -1.016  -1.015  -0.989
123   E        -0.305  -0.300  -0.238  -0.539  -0.529  -0.421  -0.557  -0.550  -0.452
124   Y         1.211   1.211   1.237   1.309   1.310   1.346   1.279   1.280   1.314
125   V         1.211   1.211   1.237   1.213   1.212   1.254   1.279   1.280   1.314
126   D         1.211   1.211   1.237   1.218   1.220   1.259   1.279   1.280   1.314
127   L         1.211   1.211   1.237   0.953   0.953   1.005   1.279   1.280   1.314
128   L        -0.019  -0.029  -0.151   0.107   0.086  -0.172  -0.098  -0.114  -0.310
129   L         1.211   1.211   1.237   0.953   0.953   1.005   1.279   1.280   1.314
130   Q         1.211   1.211   1.237   1.381   1.380   1.415   1.279   1.280   1.314
131   H         1.211   1.211   1.237   1.424   1.421   1.456   1.279   1.280   1.314
132   W         1.211   1.211   1.237   1.478   1.478   1.508   1.279   1.280   1.314
133   P         1.211   1.211   1.237   1.231   1.232   1.271   1.279   1.280   1.314
134   L        -1.063  -1.014  -1.071  -1.302  -1.227  -1.281  -1.016  -0.957  -1.007
135   C         1.211   1.211   1.237   1.507   1.505   1.536   1.279   1.280   1.314
136   F        -1.063  -1.092  -1.084  -1.165  -1.198  -1.129  -1.016  -1.051  -1.022
137   E        -1.820  -1.809  -1.713  -1.547  -1.533  -1.386  -1.475  -1.463  -1.336
138   K        -0.305  -0.298  -0.236  -0.556  -0.545  -0.438  -0.557  -0.545  -0.449
139   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
140   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
141   D         1.211   1.211   1.237   1.218   1.220   1.259   1.279   1.280   1.314
142   P        -0.305  -0.298  -0.236  -0.530  -0.514  -0.407  -0.557  -0.545  -0.449
143   K        -1.063  -1.092  -1.084  -0.926  -0.973  -0.972  -1.016  -1.051  -1.022
144   G         1.211   1.211   1.237   1.235   1.236   1.275   1.279   1.280   1.314
145   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
146   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
147   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
148   L        -0.019  -0.061  -0.158  -0.259  -0.322  -0.463  -0.098  -0.163  -0.320
149   V        -1.063  -1.092  -1.084  -1.024  -1.071  -1.059  -1.016  -1.051  -1.022
150   K        -0.019   0.021  -0.137  -0.084  -0.024  -0.259  -0.098  -0.037  -0.287
151   T        -1.820  -1.809  -1.713  -1.732  -1.718  -1.563  -1.475  -1.463  -1.336
152   P         1.211   1.211   1.237   1.231   1.232   1.271   1.279   1.280   1.314
153   V        -0.305  -0.298  -0.236  -0.572  -0.555  -0.446  -0.557  -0.545  -0.449
154   D        -0.019   0.021  -0.137   0.039   0.100  -0.141  -0.098  -0.037  -0.287
155   D        -0.019   0.012  -0.139  -0.018   0.033  -0.225  -0.098  -0.051  -0.291
156   S        -1.820  -1.809  -1.713  -1.565  -1.542  -1.403  -1.475  -1.463  -1.336
157   G         1.211   1.211   1.237   1.235   1.236   1.275   1.279   1.280   1.314
158   K        -1.820  -1.809  -1.713  -1.752  -1.734  -1.582  -1.475  -1.463  -1.336
159   T        -1.063  -1.092  -1.084  -1.247  -1.284  -1.228  -1.016  -1.051  -1.022
160   M        -1.820  -1.809  -1.713  -1.792  -1.775  -1.620  -1.475  -1.463  -1.336
161   Y         1.211   1.211   1.237   1.309   1.310   1.346   1.279   1.280   1.314
162   A        -0.019  -0.029  -0.151   0.023   0.010  -0.187  -0.098  -0.114  -0.310
163   A        -1.063  -1.092  -1.084  -1.064  -1.114  -1.103  -1.016  -1.051  -1.022
164   D        -0.019  -0.061  -0.158  -0.030  -0.097  -0.279  -0.098  -0.163  -0.320
165   G        -0.305  -0.298  -0.236  -0.465  -0.450  -0.347  -0.557  -0.545  -0.449
166   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
167   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
168   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
169   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
170   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
171   D        -1.063  -1.014  -1.071  -1.098  -1.013  -1.122  -1.016  -0.957  -1.007
172   Y        -1.063  -1.062  -1.056  -0.790  -0.785  -0.767  -1.016  -1.015  -0.989
173   L        -0.019  -0.029  -0.151  -0.097  -0.113  -0.356  -0.098  -0.114  -0.310
174   E        -0.019   0.012  -0.139  -0.063  -0.018  -0.254  -0.098  -0.051  -0.291
175   T        -0.019   0.012  -0.139   0.084   0.131  -0.123  -0.098  -0.051  -0.291
176   Y         1.211   1.211   1.237   1.309   1.310   1.346   1.279   1.280   1.314
177   K        -0.019   0.012  -0.139  -0.033   0.010  -0.190  -0.098  -0.051  -0.291
178   Q        -0.305  -0.298  -0.236  -0.446  -0.422  -0.321  -0.557  -0.545  -0.449
179   L        -0.019  -0.061  -0.158  -0.259  -0.322  -0.463  -0.098  -0.163  -0.320
180   E         1.211   1.211   1.237   1.147   1.144   1.191   1.279   1.280   1.314
181   K        -0.305  -0.298  -0.236  -0.569  -0.556  -0.450  -0.557  -0.545  -0.449
182   I         1.211   1.211   1.237   1.200   1.202   1.242   1.279   1.280   1.314
183   Y        -0.181  -0.229  -0.207  -0.288  -0.396  -0.383  -0.353  -0.431  -0.401
184   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
185   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
186   P        -1.063  -1.048  -1.052  -1.180  -1.155  -1.157  -1.016  -0.998  -0.985
187   N        -1.063  -1.014  -1.071  -0.909  -0.834  -0.929  -1.016  -0.957  -1.007
188   D        -0.305  -0.298  -0.236  -0.427  -0.414  -0.314  -0.557  -0.545  -0.449
189   H        -1.820  -1.809  -1.713  -1.604  -1.594  -1.441  -1.475  -1.463  -1.336
190   R        -0.305  -0.298  -0.236  -0.456  -0.433  -0.331  -0.557  -0.545  -0.449
191   V        -0.019   0.021  -0.137   0.019   0.077  -0.166  -0.098  -0.037  -0.287
192   R         1.211   1.211   1.237   1.369   1.367   1.403   1.279   1.280   1.314
193   A        -0.305  -0.298  -0.236  -0.380  -0.370  -0.267  -0.557  -0.545  -0.449
194   I         1.211   1.211   1.237   1.200   1.202   1.242   1.279   1.280   1.314
195   G         1.211   1.211   1.237   1.235   1.236   1.275   1.279   1.280   1.314
196   V         1.211   1.211   1.237   1.213   1.212   1.254   1.279   1.280   1.314
197   S         1.211   1.211   1.237   1.309   1.308   1.346   1.279   1.280   1.314
198   N         1.211   1.211   1.237   1.322   1.319   1.358   1.279   1.280   1.314
199   F        -0.305  -0.298  -0.236  -0.285  -0.268  -0.172  -0.557  -0.545  -0.449
200   S        -0.019  -0.061  -0.158   0.097   0.031  -0.141  -0.098  -0.163  -0.320
201   I         1.211   1.211   1.237   1.200   1.202   1.242   1.279   1.280   1.314
202   E        -0.305  -0.298  -0.236  -0.530  -0.520  -0.412  -0.557  -0.545  -0.449
203   Y        -1.063  -1.014  -1.071  -0.961  -0.880  -0.986  -1.016  -0.957  -1.007
204   L         1.211   1.211   1.237   0.953   0.953   1.005   1.279   1.280   1.314
205   E        -1.063  -1.092  -1.084  -1.003  -1.065  -1.086  -1.016  -1.051  -1.022
206   R        -1.063  -1.014  -1.071  -0.904  -0.823  -0.937  -1.016  -0.957  -1.007
207   L        -0.019  -0.061  -0.158  -0.255  -0.318  -0.456  -0.098  -0.163  -0.320
208   I        -0.019  -0.029  -0.151  -0.259  -0.273  -0.453  -0.098  -0.114  -0.310
209   K        -1.063  -1.014  -1.071  -1.075  -1.004  -1.062  -1.016  -0.957  -1.007
210   E        -0.305  -0.298  -0.236  -0.622  -0.608  -0.496  -0.557  -0.545  -0.449
211   C        -1.063  -1.014  -1.071  -0.788  -0.707  -0.840  -1.016  -0.957  -1.007
212   R        -0.305  -0.298  -0.236  -0.456  -0.433  -0.331  -0.557  -0.545  -0.449
213   V        -1.820  -1.809  -1.713  -1.789  -1.762  -1.618  -1.475  -1.463  -1.336
214   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
215   K        -1.063  -1.048  -1.052  -1.118  -1.094  -1.110  -1.016  -0.998  -0.985
216   P         1.211   1.211   1.237   1.231   1.232   1.271   1.279   1.280   1.314
217   T        -1.063  -1.092  -1.084  -1.002  -1.048  -1.025  -1.016  -1.051  -1.022
218   V        -1.063  -1.042  -1.047  -0.917  -0.875  -0.936  -1.016  -0.990  -0.979
219   N         1.211   1.211   1.237   1.322   1.319   1.358   1.279   1.280   1.314
220   Q         1.211   1.211   1.237   1.381   1.380   1.415   1.279   1.280   1.314
221   V        -0.305  -0.298  -0.236  -0.504  -0.489  -0.384  -0.557  -0.545  -0.449
222   E         1.211   1.211   1.237   1.147   1.144   1.191   1.279   1.280   1.314
223   T        -1.063  -1.092  -1.084  -1.054  -1.113  -1.126  -1.016  -1.051  -1.022
224   H         1.211   1.211   1.237   1.424   1.421   1.456   1.279   1.280   1.314
225   P         1.211   1.211   1.237   1.231   1.232   1.271   1.279   1.280   1.314
226   H        -0.305  -0.298  -0.236  -0.221  -0.209  -0.113  -0.557  -0.545  -0.449
227   L         1.211   1.211   1.237   0.953   0.953   1.005   1.279   1.280   1.314
228   P         1.211   1.211   1.237   1.231   1.232   1.271   1.279   1.280   1.314
229   Q         1.211   1.211   1.237   1.381   1.380   1.415   1.279   1.280   1.314
230   M        -1.063  -1.092  -1.084  -0.721  -0.765  -0.742  -1.016  -1.051  -1.022
231   E        -0.305  -0.298  -0.236  -0.539  -0.528  -0.420  -0.557  -0.545  -0.449
232   L         1.211   1.211   1.237   0.953   0.953   1.005   1.279   1.280   1.314
233   R        -1.063  -1.092  -1.084  -0.872  -0.908  -0.867  -1.016  -1.051  -1.022
234   K        -1.063  -1.092  -1.084  -1.137  -1.189  -1.194  -1.016  -1.051  -1.022
235   F        -0.019   0.012  -0.139   0.216   0.261   0.012  -0.098  -0.051  -0.291
236   C         1.211   1.211   1.237   1.507   1.505   1.536   1.279   1.280   1.314
237   F        -1.820  -1.809  -1.713  -1.478  -1.462  -1.320  -1.475  -1.463  -1.336
238   M        -1.063  -1.092  -1.084  -1.039  -1.083  -1.032  -1.016  -1.051  -1.022
239   H        -0.019   0.012  -0.139   0.236   0.280   0.032  -0.098  -0.051  -0.291
240   D        -1.063  -1.048  -1.052  -1.108  -1.085  -1.075  -1.016  -0.998  -0.985
241   I         1.211   1.211   1.237   1.200   1.202   1.242   1.279   1.280   1.314
242   L         1.211   1.211   1.237   0.953   0.953   1.005   1.279   1.280   1.314
243   L        -1.063  -1.048  -1.052  -1.184  -1.162  -1.185  -1.016  -0.998  -0.985
244   T        -1.063  -1.014  -1.071  -0.977  -0.897  -1.003  -1.016  -0.957  -1.007
245   A        -0.019   0.012  -0.139   0.154   0.194  -0.009  -0.098  -0.051  -0.291
246   Y         1.211   1.211   1.237   1.309   1.310   1.346   1.279   1.280   1.314
247   S         1.211   1.211   1.237   1.309   1.308   1.346   1.279   1.280   1.314
248   P         1.211   1.211   1.237   1.231   1.232   1.271   1.279   1.280   1.314
249   L        -0.305  -0.298  -0.236  -0.686  -0.682  -0.566  -0.557  -0.545  -0.449
250   G         1.211   1.211   1.237   1.235   1.236   1.275   1.279   1.280   1.314
251   S        -0.305  -0.301  -0.238  -0.408  -0.400  -0.297  -0.557  -0.550  -0.453
252   H        -1.820  -1.809  -1.713  -1.536  -1.514  -1.375  -1.475  -1.463  -1.336
253   G         1.211   1.211   1.237   1.235   1.236   1.275   1.279   1.280   1.314
254   A         1.211   1.211   1.237   1.274   1.272   1.313   1.279   1.280   1.314
255   P         1.211   1.211   1.237   1.231   1.232   1.271   1.279   1.280   1.314
256   N        -1.063  -1.092  -1.084  -1.129  -1.189  -1.183  -1.016  -1.051  -1.022
257   L         1.211   1.211   1.237   0.953   0.953   1.005   1.279   1.280   1.314
258   K        -0.019  -0.061  -0.158  -0.126  -0.193  -0.356  -0.098  -0.163  -0.320
259   I        -0.305  -0.301  -0.238  -0.696  -0.687  -0.573  -0.557  -0.550  -0.453
260   P         1.211   1.211   1.237   1.231   1.232   1.271   1.279   1.280   1.314
261   L        -1.063  -1.062  -1.056  -1.257  -1.255  -1.212  -1.016  -1.015  -0.989
262   V        -1.063  -1.062  -1.056  -1.184  -1.192  -1.192  -1.016  -1.015  -0.989
263   K        -0.019   0.021  -0.137  -0.068  -0.009  -0.236  -0.098  -0.037  -0.287
264   K        -1.820  -1.809  -1.713  -1.759  -1.743  -1.589  -1.475  -1.463  -1.336
265   L         1.211   1.211   1.237   0.953   0.953   1.005   1.279   1.280   1.314
266   A        -0.019  -0.061  -0.158   0.154   0.094  -0.036  -0.098  -0.163  -0.320
267   E         1.211   1.211   1.237   1.147   1.144   1.191   1.279   1.280   1.314
268   K         1.211   1.211   1.237   1.107   1.108   1.153   1.279   1.280   1.314
269   Y         1.211   1.211   1.237   1.309   1.310   1.346   1.279   1.280   1.314
270   N        -1.063  -1.014  -1.071  -0.928  -0.851  -0.951  -1.016  -0.957  -1.007
271   V        -0.019  -0.061  -0.158   0.019  -0.047  -0.201  -0.098  -0.163  -0.320
272   T        -0.305  -0.301  -0.238  -0.361  -0.354  -0.252  -0.557  -0.550  -0.453
273   G        -1.820  -1.809  -1.713  -1.787  -1.765  -1.615  -1.475  -1.463  -1.336
274   N         1.211   1.211   1.237   1.322   1.319   1.358   1.279   1.280   1.314
275   D        -0.305  -0.298  -0.236  -0.539  -0.523  -0.416  -0.557  -0.545  -0.449
276   L        -0.019  -0.029  -0.151  -0.097  -0.113  -0.356  -0.098  -0.114  -0.310
277   L        -1.063  -1.014  -1.071  -1.226  -1.159  -1.193  -1.016  -0.957  -1.007
278   I        -1.820  -1.809  -1.713  -1.668  -1.647  -1.501  -1.475  -1.463  -1.336
279   S        -0.305  -0.298  -0.236  -0.380  -0.367  -0.265  -0.557  -0.545  -0.449
280   Y         1.211   1.211   1.237   1.309   1.310   1.346   1.279   1.280   1.314
281   H        -0.019   0.012  -0.139   0.236   0.280   0.032  -0.098  -0.051  -0.291
282   I        -0.019  -0.061  -0.158  -0.097  -0.169  -0.369  -0.098  -0.163  -0.320
283   R        -0.305  -0.298  -0.236  -0.566  -0.537  -0.431  -0.557  -0.545  -0.449
284   Q        -0.019   0.012  -0.139   0.196   0.241  -0.004  -0.098  -0.051  -0.291
285   G         1.211   1.211   1.237   1.235   1.236   1.275   1.279   1.280   1.314
286   T        -0.305  -0.298  -0.236  -0.318  -0.309  -0.209  -0.557  -0.545  -0.449
287   I        -0.019   0.012  -0.139  -0.013   0.035  -0.210  -0.098  -0.051  -0.291
288   V        -0.305  -0.298  -0.236  -0.430  -0.421  -0.317  -0.557  -0.545  -0.449
289   I        -0.305  -0.298  -0.236  -0.696  -0.670  -0.560  -0.557  -0.545  -0.449
290   P         1.211   1.211   1.237   1.231   1.232   1.271   1.279   1.280   1.314
291   R         1.211   1.211   1.237   1.369   1.367   1.403   1.279   1.280   1.314
292   S         1.211   1.211   1.237   1.309   1.308   1.346   1.279   1.280   1.314
293   L        -0.305  -0.298  -0.236  -0.612  -0.612  -0.498  -0.557  -0.545  -0.449
294   N         1.211   1.211   1.237   1.322   1.319   1.358   1.279   1.280   1.314
295   P        -1.063  -1.092  -1.084  -1.243  -1.278  -1.223  -1.016  -1.051  -1.022
296   V        -1.063  -1.092  -1.084  -1.085  -1.131  -1.103  -1.016  -1.051  -1.022
297   R         1.211   1.211   1.237   1.369   1.367   1.403   1.279   1.280   1.314
298   I         1.211   1.211   1.237   1.200   1.202   1.242   1.279   1.280   1.314
299   S        -1.063  -1.092  -1.084  -1.089  -1.130  -1.093  -1.016  -1.051  -1.022
300   S        -0.305  -0.298  -0.236  -0.361  -0.348  -0.248  -0.557  -0.545  -0.449
301   S        -1.063  -1.048  -1.052  -0.937  -0.912  -0.930  -1.016  -0.998  -0.985
302   I        -1.063  -1.062  -1.056  -1.190  -1.197  -1.196  -1.016  -1.015  -0.989
303   E        -0.305  -0.298  -0.236  -0.427  -0.425  -0.318  -0.557  -0.545  -0.449
304   F        -0.305  -0.298  -0.236  -0.536  -0.506  -0.402  -0.557  -0.545  -0.449
305   A        -1.063  -1.092  -1.084  -1.024  -1.073  -1.059  -1.016  -1.051  -1.022
306   S        -1.820  -1.809  -1.713  -1.504  -1.495  -1.345  -1.475  -1.463  -1.336
307   L         1.211   1.211   1.237   0.953   0.953   1.005   1.279   1.280   1.314
308   T        -0.019  -0.061  -0.158   0.114   0.050  -0.111  -0.098  -0.163  -0.320
309   K        -0.019  -0.061  -0.158  -0.126  -0.193  -0.356  -0.098  -0.163  -0.320
310   D        -0.305  -0.300  -0.238  -0.539  -0.531  -0.422  -0.557  -0.550  -0.452
311   E        -0.019  -0.061  -0.158  -0.063  -0.130  -0.286  -0.098  -0.163  -0.320
312   L        -0.019  -0.061  -0.158  -0.255  -0.318  -0.456  -0.098  -0.163  -0.320
313   Q        -1.063  -1.092  -1.084  -0.942  -0.983  -0.954  -1.016  -1.051  -1.022
314   E        -0.305  -0.301  -0.238  -0.622  -0.615  -0.501  -0.557  -0.550  -0.453
315   L         1.211   1.211   1.237   0.953   0.953   1.005   1.279   1.280   1.314
316   N        -0.305  -0.298  -0.236  -0.346  -0.333  -0.233  -0.557  -0.545  -0.449
317   D        -1.063  -1.092  -1.084  -0.946  -1.003  -1.019  -1.016  -1.051  -1.022
318   F        -1.063  -1.014  -1.071  -0.904  -0.821  -0.948  -1.016  -0.957  -1.007
319   G         1.211   1.211   1.237   1.235   1.236   1.275   1.279   1.280   1.314
320   E        -1.063  -1.092  -1.084  -1.020  -1.065  -1.048  -1.016  -1.051  -1.022
321   K        -0.019   0.021  -0.137  -0.126  -0.063  -0.319  -0.098  -0.037  -0.287
322   Y        -1.063  -1.048  -1.052  -0.929  -0.904  -0.921  -1.016  -0.998  -0.985
323   P        -0.019  -0.061  -0.158  -0.018  -0.086  -0.268  -0.098  -0.163  -0.320
324   V        -1.820  -1.809  -1.713  -1.687  -1.680  -1.519  -1.475  -1.463  -1.336
325   R         1.211   1.211   1.237   1.369   1.367   1.403   1.279   1.280   1.314
326   F        -0.019  -0.029  -0.151   0.154   0.140  -0.046  -0.098  -0.114  -0.310
327   I        -0.019   0.021  -0.137  -0.097  -0.027  -0.326  -0.098  -0.037  -0.287
328   D        -1.820  -1.809  -1.713  -1.547  -1.532  -1.386  -1.475  -1.463  -1.336
329   E        -1.063  -1.092  -1.084  -1.081  -1.128  -1.125  -1.016  -1.051  -1.022
330   P        -1.063  -1.062  -1.056  -0.983  -0.983  -0.967  -1.016  -1.015  -0.989
331   F        -1.063  -1.092  -1.084  -0.759  -0.813  -0.823  -1.016  -1.051  -1.022
332   A        -1.063  -1.092  -1.084  -0.979  -1.023  -1.006  -1.016  -1.051  -1.022
333   A        -1.063  -1.092  -1.084  -0.917  -0.963  -0.956  -1.016  -1.051  -1.022
334   I        -1.063  -1.092  -1.084  -1.052  -1.101  -1.096  -1.016  -1.051  -1.022
335   L        -0.019  -0.029  -0.151  -0.097  -0.113  -0.356  -0.098  -0.114  -0.310
336   P        -0.305  -0.298  -0.236  -0.465  -0.450  -0.348  -0.557  -0.545  -0.449
337   E        -1.063  -1.092  -1.084  -0.917  -0.973  -0.992  -1.016  -1.051  -1.022
338   F        -0.305  -0.298  -0.236  -0.242  -0.230  -0.133  -0.557  -0.545  -0.449
339   T        -1.063  -1.092  -1.084  -0.845  -0.904  -0.929  -1.016  -1.051  -1.022
340   G        -1.063  -1.092  -1.084  -0.855  -0.915  -0.943  -1.016  -1.051  -1.022
341   N        -1.063  -1.092  -1.084  -1.108  -1.150  -1.116  -1.016  -1.051  -1.022
342   G        -0.019  -0.061  -0.158   0.084   0.024  -0.117  -0.098  -0.163  -0.320
343   P        -1.063  -1.092  -1.084  -1.167  -1.223  -1.231  -1.016  -1.051  -1.022
344   N        -1.063  -1.092  -1.084  -0.988  -1.043  -1.041  -1.016  -1.051  -1.022
345   L        -1.063  -1.062  -1.056  -1.200  -1.208  -1.148  -1.016  -1.015  -0.989
346   D        -1.063  -1.092  -1.084  -0.909  -0.954  -0.947  -1.016  -1.051  -1.022
347   N        -1.063  -1.092  -1.084  -1.224  -1.279  -1.260  -1.016  -1.051  -1.022
348   L        -1.063  -1.092  -1.084  -1.161  -1.207  -1.196  -1.016  -1.051  -1.022
349   K        -1.063  -1.092  -1.084  -0.872  -0.922  -0.936  -1.016  -1.051  -1.022
350   Y        -1.063  -1.092  -1.084  -0.979  -1.020  -0.999  -1.016  -1.051  -1.022
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P38115
Output conservation file - output/P38115
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
