1     M         1.315   1.325   1.355   1.490   1.503   1.548   1.409   1.422   1.465
2     G         1.315   1.325   1.355   1.248   1.268   1.317   1.409   1.422   1.465
3     Q         1.315   1.325   1.355   1.481   1.501   1.539   1.409   1.422   1.465
4     L         1.315   1.325   1.355   1.137   1.150   1.210   1.409   1.422   1.465
5     L         1.315   1.325   1.355   1.137   1.150   1.210   1.409   1.422   1.465
6     S         1.315   1.325   1.355   1.261   1.280   1.328   1.409   1.422   1.465
7     H         1.315   1.325   1.355   1.458   1.475   1.517   1.409   1.422   1.465
8     P         1.315   1.325   1.355   1.498   1.514   1.556   1.409   1.422   1.465
9     L        -0.074  -0.092  -0.030  -0.426  -0.461  -0.344  -0.338  -0.369  -0.277
10    T        -0.074  -0.092  -0.030  -0.159  -0.191  -0.093  -0.338  -0.369  -0.277
11    E         0.282   0.230   0.085   0.402   0.324   0.089   0.244   0.163  -0.081
12    K         1.315   1.325   1.355   1.273   1.284   1.340   1.409   1.422   1.465
13    T         0.282   0.240   0.085   0.409   0.354   0.108   0.244   0.179  -0.081
14    I        -0.647  -0.725  -0.792  -0.623  -0.744  -0.849  -0.629  -0.724  -0.802
15    E        -0.647  -0.678  -0.761  -0.530  -0.582  -0.733  -0.629  -0.664  -0.763
16    Y         0.282   0.230   0.085   0.502   0.433   0.209   0.244   0.163  -0.081
17    N        -0.074  -0.092  -0.030  -0.299  -0.335  -0.230  -0.338  -0.369  -0.277
18    E        -0.863  -0.814  -0.826  -0.949  -0.882  -0.869  -0.920  -0.860  -0.845
19    Y         1.315   1.325   1.355   1.437   1.452   1.497   1.409   1.422   1.465
20    K        -1.435  -1.476  -1.413  -1.294  -1.351  -1.240  -1.211  -1.243  -1.151
21    N        -0.074  -0.062  -0.028  -0.219  -0.193  -0.158  -0.338  -0.317  -0.275
22    N        -0.953  -0.934  -0.848  -1.141  -1.110  -0.970  -1.017  -0.988  -0.870
23    Q        -0.953  -0.934  -0.848  -1.099  -1.073  -0.930  -1.017  -0.988  -0.870
24    A        -0.953  -0.934  -0.848  -1.020  -0.978  -0.854  -1.017  -0.988  -0.870
25    S        -0.953  -0.934  -0.848  -1.093  -1.061  -0.924  -1.017  -0.988  -0.870
26    T        -0.953  -0.934  -0.848  -1.123  -1.109  -0.952  -1.017  -0.988  -0.870
27    G         0.001  -0.040  -0.020  -0.231  -0.307  -0.283  -0.209  -0.280  -0.260
28    I        -0.953  -0.934  -0.848  -1.242  -1.221  -1.066  -1.017  -0.988  -0.870
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    V         0.001  -0.040  -0.020  -0.112  -0.190  -0.169  -0.209  -0.280  -0.260
39    P         1.315   1.325   1.355   1.495   1.510   1.553   1.409   1.422   1.465
40    R         1.315   1.325   1.355   1.403   1.421   1.465   1.409   1.422   1.465
41    F        -0.647  -0.725  -0.792  -0.560  -0.693  -0.851  -0.629  -0.724  -0.802
42    Y        -0.074  -0.092  -0.030  -0.101  -0.136  -0.044  -0.338  -0.369  -0.277
43    N        -0.074  -0.092  -0.030  -0.203  -0.226  -0.122  -0.338  -0.369  -0.277
44    C         1.315   1.325   1.355   1.545   1.560   1.600   1.409   1.422   1.465
45    V        -0.074  -0.092  -0.030  -0.286  -0.328  -0.223  -0.338  -0.369  -0.277
46    G         1.315   1.325   1.355   1.248   1.268   1.317   1.409   1.422   1.465
47    S         0.282   0.230   0.085   0.250   0.173  -0.084   0.244   0.163  -0.081
48    M         1.315   1.325   1.355   1.490   1.503   1.548   1.409   1.422   1.465
49    Q         1.315   1.325   1.355   1.481   1.501   1.539   1.409   1.422   1.465
50    G         1.315   1.325   1.355   1.248   1.268   1.317   1.409   1.422   1.465
51    Y         1.315   1.325   1.355   1.437   1.452   1.497   1.409   1.422   1.465
52    R         1.315   1.325   1.355   1.431   1.450   1.492   1.409   1.422   1.465
53    L        -0.074  -0.092  -0.030  -0.281  -0.298  -0.182  -0.338  -0.369  -0.277
54    T        -0.074  -0.065  -0.028  -0.222  -0.202  -0.162  -0.338  -0.323  -0.275
55    Q        -0.074  -0.092  -0.030   0.006  -0.022   0.068  -0.338  -0.369  -0.277
56    E         1.315   1.325   1.355   1.372   1.385   1.435   1.409   1.422   1.465
57    D         1.315   1.325   1.355   1.309   1.322   1.375   1.409   1.422   1.465
58    A         1.315   1.325   1.355   1.369   1.385   1.432   1.409   1.422   1.465
59    H         1.315   1.325   1.355   1.458   1.475   1.517   1.409   1.422   1.465
60    L        -1.435  -1.447  -1.400  -1.539  -1.557  -1.467  -1.211  -1.215  -1.139
61    I         0.282   0.356   0.102   0.314   0.419   0.027   0.244   0.356  -0.052
62    R        -0.647  -0.532  -0.747  -0.511  -0.354  -0.637  -0.629  -0.477  -0.746
63    N        -1.435  -1.476  -1.413  -1.402  -1.465  -1.366  -1.211  -1.243  -1.151
64    E        -0.863  -0.843  -0.829  -0.944  -0.915  -0.891  -0.920  -0.888  -0.849
65    N        -1.435  -1.354  -1.402  -1.344  -1.209  -1.314  -1.211  -1.120  -1.141
66    S        -2.007  -1.987  -1.873  -1.757  -1.715  -1.559  -1.503  -1.475  -1.337
67    V        -1.435  -1.354  -1.402  -1.356  -1.221  -1.328  -1.211  -1.120  -1.141
68    V         0.001   0.040  -0.008  -0.247  -0.187  -0.257  -0.209  -0.143  -0.240
69    Y        -0.953  -0.934  -0.848  -0.949  -0.927  -0.786  -1.017  -0.988  -0.870
70    V         1.315   1.325   1.355   1.314   1.330   1.380   1.409   1.422   1.465
71    R         0.001  -0.040  -0.020  -0.056  -0.138  -0.133  -0.209  -0.280  -0.260
72    F         1.315   1.325   1.355   1.380   1.396   1.443   1.409   1.422   1.465
73    F         0.001  -0.040  -0.020   0.017  -0.053  -0.027  -0.209  -0.280  -0.260
74    N         0.001  -0.040  -0.020  -0.125  -0.192  -0.169  -0.209  -0.280  -0.260
75    P         1.315   1.325   1.355   1.495   1.510   1.553   1.409   1.422   1.465
76    F         1.315   1.325   1.355   1.380   1.396   1.443   1.409   1.422   1.465
77    I         0.001   0.047  -0.005  -0.116  -0.038  -0.134  -0.209  -0.132  -0.234
78    D         0.001   0.040  -0.008  -0.182  -0.115  -0.198  -0.209  -0.143  -0.240
79    K         1.315   1.325   1.355   1.314   1.328   1.380   1.409   1.422   1.465
80    Y        -0.953  -0.934  -0.848  -0.913  -0.890  -0.751  -1.017  -0.988  -0.870
81    E         0.001  -0.040  -0.020  -0.011  -0.089  -0.076  -0.209  -0.280  -0.260
82    T         0.001   0.040  -0.008  -0.086  -0.019  -0.113  -0.209  -0.143  -0.240
83    L        -0.953  -0.934  -0.848  -0.952  -0.915  -0.789  -1.017  -0.988  -0.870
84    S        -1.435  -1.418  -1.376  -1.269  -1.245  -1.167  -1.211  -1.185  -1.116
85    L        -0.074  -0.044  -0.010  -0.426  -0.377  -0.312  -0.338  -0.286  -0.243
86    N        -0.863  -0.814  -0.826  -0.944  -0.859  -0.879  -0.920  -0.860  -0.845
87    V        -0.647  -0.585  -0.745  -0.543  -0.458  -0.688  -0.629  -0.546  -0.743
88    F         1.315   1.325   1.355   1.396   1.414   1.458   1.409   1.422   1.465
89    A        -0.074  -0.092  -0.030  -0.224  -0.262  -0.168  -0.338  -0.369  -0.277
90    V         0.282   0.240   0.085   0.314   0.251  -0.003   0.244   0.179  -0.081
91    F         1.315   1.325   1.355   1.396   1.414   1.458   1.409   1.422   1.465
92    D         1.315   1.325   1.355   1.309   1.322   1.375   1.409   1.422   1.465
93    G         1.315   1.325   1.355   1.248   1.268   1.317   1.409   1.422   1.465
94    H         1.315   1.325   1.355   1.458   1.475   1.517   1.409   1.422   1.465
95    G         1.315   1.325   1.355   1.248   1.268   1.317   1.409   1.422   1.465
96    G         0.282   0.292   0.095   0.280   0.300  -0.003   0.244   0.260  -0.064
97    D        -0.863  -0.843  -0.829  -0.979  -0.950  -0.918  -0.920  -0.888  -0.849
98    D        -1.435  -1.388  -1.379  -1.392  -1.311  -1.304  -1.211  -1.156  -1.119
99    C         1.315   1.325   1.355   1.545   1.560   1.600   1.409   1.422   1.465
100   S         0.282   0.230   0.085   0.308   0.240   0.017   0.244   0.163  -0.081
101   K        -1.435  -1.476  -1.413  -1.308  -1.358  -1.256  -1.211  -1.243  -1.151
102   F        -0.863  -0.877  -0.813  -0.791  -0.804  -0.711  -0.920  -0.925  -0.830
103   L         0.282   0.230   0.085   0.167   0.091  -0.124   0.244   0.163  -0.081
104   S        -0.074  -0.078  -0.031  -0.248  -0.251  -0.173  -0.338  -0.346  -0.279
105   G        -0.647  -0.725  -0.792  -0.608  -0.721  -0.826  -0.629  -0.724  -0.802
106   G        -1.547  -1.535  -1.425  -1.536  -1.520  -1.348  -1.321  -1.299  -1.162
107   R         0.154   0.148   0.063   0.009   0.003  -0.107   0.044   0.034  -0.117
108   H        -0.831  -0.839  -0.822  -0.584  -0.595  -0.584  -0.866  -0.870  -0.839
109   -        -0.953  -0.932  -0.848  -1.038  -0.993  -0.872  -1.017  -0.985  -0.870
110   -        -0.953  -0.932  -0.848  -0.979  -0.924  -0.815  -1.017  -0.985  -0.870
111   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
112   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
113   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
114   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
115   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
116   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
117   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
118   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
119   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
120   N        -0.953  -0.934  -0.848  -1.061  -1.022  -0.893  -1.017  -0.988  -0.870
121   G        -0.953  -0.934  -0.848  -1.123  -1.072  -0.952  -1.017  -0.988  -0.870
122   N         0.001  -0.040  -0.020  -0.147  -0.218  -0.198  -0.209  -0.280  -0.260
123   G        -0.953  -0.934  -0.848  -1.108  -1.095  -0.938  -1.017  -0.988  -0.870
124   E        -0.953  -0.934  -0.848  -0.918  -0.890  -0.757  -1.017  -0.988  -0.870
125   P        -0.953  -0.934  -0.848  -0.989  -0.951  -0.824  -1.017  -0.988  -0.870
126   N        -0.953  -0.934  -0.848  -0.957  -0.914  -0.794  -1.017  -0.988  -0.870
127   A         0.001  -0.040  -0.020  -0.056  -0.135  -0.111  -0.209  -0.280  -0.260
128   G         1.315   1.325   1.355   1.215   1.232   1.284   1.409   1.422   1.465
129   L         1.315   1.325   1.355   1.152   1.162   1.224   1.409   1.422   1.465
130   I         0.001   0.047  -0.005  -0.109  -0.035  -0.125  -0.209  -0.132  -0.234
131   K         0.001  -0.040  -0.020  -0.038  -0.107  -0.072  -0.209  -0.280  -0.260
132   W         0.001  -0.040  -0.020   0.195   0.115   0.113  -0.209  -0.280  -0.260
133   I         0.001   0.047  -0.005  -0.127  -0.049  -0.147  -0.209  -0.132  -0.234
134   A        -0.953  -0.934  -0.848  -1.037  -1.009  -0.871  -1.017  -0.988  -0.870
135   Y         0.001  -0.040  -0.020  -0.053  -0.148  -0.147  -0.209  -0.280  -0.260
136   S         0.001  -0.040  -0.020  -0.162  -0.233  -0.196  -0.209  -0.280  -0.260
137   F         1.315   1.325   1.355   1.380   1.396   1.443   1.409   1.422   1.465
138   E         1.315   1.325   1.355   1.408   1.424   1.469   1.409   1.422   1.465
139   N         0.001  -0.040  -0.020  -0.173  -0.247  -0.233  -0.209  -0.280  -0.260
140   H         1.315   1.325   1.355   1.431   1.446   1.491   1.409   1.422   1.465
141   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
142   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
143   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
144   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
145   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
146   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
147   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
148   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
149   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
150   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
151   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
152   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
153   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
154   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
155   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
156   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
157   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
158   H        -1.435  -1.354  -1.402  -1.339  -1.217  -1.286  -1.211  -1.120  -1.141
159   Y        -0.074  -0.092  -0.030  -0.083  -0.117  -0.024  -0.338  -0.369  -0.277
160   T         0.282   0.230   0.085   0.424   0.358   0.134   0.244   0.163  -0.081
161   S        -1.435  -1.447  -1.400  -1.406  -1.419  -1.350  -1.211  -1.215  -1.139
162   T        -0.863  -0.843  -0.829  -0.988  -0.967  -0.911  -0.920  -0.888  -0.849
163   T        -1.435  -1.383  -1.378  -1.314  -1.242  -1.218  -1.211  -1.151  -1.118
164   N        -0.831  -0.847  -0.834  -0.965  -0.989  -0.976  -0.866  -0.880  -0.853
165   N         0.001  -0.081  -0.020  -0.200  -0.356  -0.249  -0.209  -0.350  -0.260
166   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
167   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
168   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
169   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
170   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
171   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
172   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
173   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
174   D        -1.547  -1.488  -1.425  -1.460  -1.351  -1.275  -1.321  -1.255  -1.162
175   S         0.154   0.193   0.050   0.149   0.215   0.007   0.044   0.106  -0.140
176   S        -1.547  -1.488  -1.425  -1.513  -1.398  -1.325  -1.321  -1.255  -1.162
177   K        -1.547  -1.488  -1.425  -1.627  -1.514  -1.435  -1.321  -1.255  -1.162
178   F        -0.831  -0.732  -0.793  -0.738  -0.575  -0.693  -0.866  -0.734  -0.803
179   K        -0.863  -0.814  -0.824  -1.067  -1.009  -0.975  -0.920  -0.860  -0.844
180   R        -0.647  -0.725  -0.792  -0.519  -0.651  -0.812  -0.629  -0.724  -0.802
181   S        -1.435  -1.388  -1.379  -1.191  -1.116  -1.125  -1.211  -1.156  -1.119
182   F        -0.647  -0.725  -0.792  -0.505  -0.628  -0.768  -0.629  -0.724  -0.802
183   N        -1.435  -1.447  -1.402  -1.314  -1.336  -1.298  -1.211  -1.215  -1.141
184   T        -0.647  -0.725  -0.792  -0.533  -0.653  -0.788  -0.629  -0.724  -0.802
185   L        -1.435  -1.447  -1.400  -1.476  -1.506  -1.395  -1.211  -1.215  -1.139
186   E        -0.074  -0.092  -0.030  -0.187  -0.229  -0.127  -0.338  -0.369  -0.277
187   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
188   G        -0.647  -0.725  -0.792  -0.620  -0.734  -0.845  -0.629  -0.724  -0.802
189   L        -0.647  -0.725  -0.792  -0.751  -0.870  -0.967  -0.629  -0.724  -0.802
190   V        -0.863  -0.881  -0.813  -0.943  -0.960  -0.836  -0.920  -0.931  -0.830
191   S        -1.435  -1.476  -1.413  -1.191  -1.230  -1.115  -1.211  -1.243  -1.151
192   Q        -0.647  -0.725  -0.792  -0.420  -0.544  -0.694  -0.629  -0.724  -0.802
193   I        -0.074  -0.081  -0.031  -0.300  -0.317  -0.230  -0.338  -0.350  -0.279
194   F        -0.863  -0.814  -0.826  -1.073  -1.015  -0.978  -0.920  -0.860  -0.845
195   K         1.315   1.325   1.355   1.273   1.284   1.340   1.409   1.422   1.465
196   D         0.282   0.240   0.085   0.330   0.267   0.015   0.244   0.179  -0.081
197   A        -0.074  -0.020   0.004  -0.248  -0.153  -0.118  -0.338  -0.245  -0.219
198   F         0.282   0.356   0.105   0.457   0.561   0.197   0.244   0.356  -0.048
199   I        -0.863  -0.843  -0.829  -0.931  -0.885  -0.868  -0.920  -0.888  -0.849
200   L        -1.435  -1.422  -1.375  -1.383  -1.351  -1.291  -1.211  -1.191  -1.116
201   Q        -0.863  -0.843  -0.829  -0.775  -0.756  -0.696  -0.920  -0.888  -0.849
202   D         1.315   1.325   1.355   1.309   1.322   1.375   1.409   1.422   1.465
203   E        -2.007  -1.987  -1.873  -1.676  -1.649  -1.481  -1.503  -1.475  -1.337
204   E        -0.863  -0.843  -0.829  -0.872  -0.844  -0.806  -0.920  -0.888  -0.849
205   L         0.282   0.292   0.095   0.193   0.207  -0.064   0.244   0.260  -0.064
206   Y        -1.435  -1.447  -1.402  -1.183  -1.205  -1.153  -1.211  -1.215  -1.141
207   R        -2.007  -1.987  -1.873  -1.683  -1.657  -1.488  -1.503  -1.475  -1.337
208   H         0.282   0.230   0.085   0.502   0.430   0.191   0.244   0.163  -0.081
209   F         0.154  -0.004   0.021   0.246  -0.009   0.016   0.044  -0.217  -0.189
210   A        -0.647  -0.725  -0.792  -0.527  -0.650  -0.783  -0.629  -0.724  -0.802
211   N        -0.647  -0.725  -0.792  -0.568  -0.678  -0.777  -0.629  -0.724  -0.802
212   S        -0.647  -0.678  -0.761  -0.600  -0.644  -0.773  -0.629  -0.664  -0.763
213   S        -0.863  -0.814  -0.826  -0.942  -0.869  -0.878  -0.920  -0.860  -0.845
214   C         0.282   0.292   0.095   0.561   0.577   0.241   0.244   0.260  -0.064
215   G         1.315   1.325   1.355   1.248   1.268   1.317   1.409   1.422   1.465
216   S         0.282   0.230   0.085   0.306   0.239   0.014   0.244   0.163  -0.081
217   T         1.315   1.325   1.355   1.363   1.382   1.426   1.409   1.422   1.465
218   A         1.315   1.325   1.355   1.369   1.385   1.432   1.409   1.422   1.465
219   V        -0.863  -0.872  -0.812  -0.970  -0.977  -0.871  -0.920  -0.919  -0.829
220   V         0.282   0.230   0.085   0.314   0.235  -0.003   0.244   0.163  -0.081
221   A         0.282   0.240   0.085   0.397   0.337   0.081   0.244   0.179  -0.081
222   C        -1.435  -1.447  -1.402  -1.397  -1.418  -1.308  -1.211  -1.215  -1.141
223   I         0.282   0.292   0.095   0.238   0.250  -0.076   0.244   0.260  -0.064
224   I         1.315   1.325   1.355   1.248   1.261   1.317   1.409   1.422   1.465
225   N        -0.074  -0.092  -0.030  -0.243  -0.269  -0.167  -0.338  -0.369  -0.277
226   E        -0.863  -0.814  -0.826  -0.988  -0.915  -0.905  -0.920  -0.860  -0.845
227   E        -0.831  -0.721  -0.793  -0.814  -0.635  -0.768  -0.866  -0.720  -0.804
228   S        -0.863  -0.814  -0.826  -0.738  -0.665  -0.692  -0.920  -0.860  -0.845
229   L        -0.074  -0.092  -0.030  -0.426  -0.461  -0.344  -0.338  -0.369  -0.277
230   Y        -0.647  -0.725  -0.792  -0.472  -0.600  -0.745  -0.629  -0.724  -0.802
231   V         1.315   1.325   1.355   1.297   1.311   1.363   1.409   1.422   1.465
232   A         0.282   0.230   0.085   0.388   0.313   0.066   0.244   0.163  -0.081
233   N         1.315   1.325   1.355   1.267   1.284   1.334   1.409   1.422   1.465
234   C        -0.863  -0.877  -0.813  -0.714  -0.735  -0.648  -0.920  -0.925  -0.830
235   G         1.315   1.325   1.355   1.248   1.268   1.317   1.409   1.422   1.465
236   D         1.315   1.325   1.355   1.309   1.322   1.375   1.409   1.422   1.465
237   S         1.315   1.325   1.355   1.261   1.280   1.328   1.409   1.422   1.465
238   R         1.315   1.325   1.355   1.431   1.450   1.492   1.409   1.422   1.465
239   C         1.315   1.325   1.355   1.545   1.560   1.600   1.409   1.422   1.465
240   I         1.315   1.325   1.355   1.248   1.261   1.317   1.409   1.422   1.465
241   L        -0.647  -0.725  -0.792  -0.678  -0.787  -0.858  -0.629  -0.724  -0.802
242   S         1.315   1.325   1.355   1.261   1.280   1.328   1.409   1.422   1.465
243   S        -1.435  -1.476  -1.413  -1.434  -1.498  -1.402  -1.211  -1.243  -1.151
244   K        -0.647  -0.725  -0.792  -0.598  -0.720  -0.827  -0.629  -0.724  -0.802
245   S        -1.435  -1.354  -1.402  -1.423  -1.290  -1.369  -1.211  -1.120  -1.141
246   N        -2.007  -1.987  -1.873  -1.799  -1.763  -1.599  -1.503  -1.475  -1.337
247   G        -0.074  -0.020   0.004  -0.224  -0.116  -0.095  -0.338  -0.245  -0.219
248   I         0.154  -0.006   0.021   0.168  -0.073  -0.019   0.044  -0.221  -0.189
249   K         1.315   1.325   1.355   1.273   1.284   1.340   1.409   1.422   1.465
250   T        -0.074  -0.078  -0.031  -0.087  -0.088  -0.013  -0.338  -0.346  -0.279
251   M        -0.074  -0.092  -0.030  -0.180  -0.239  -0.146  -0.338  -0.369  -0.277
252   S         1.315   1.325   1.355   1.261   1.280   1.328   1.409   1.422   1.465
253   F        -0.074  -0.044  -0.010  -0.094  -0.041   0.006  -0.338  -0.286  -0.243
254   D         1.315   1.325   1.355   1.309   1.322   1.375   1.409   1.422   1.465
255   H         1.315   1.325   1.355   1.458   1.475   1.517   1.409   1.422   1.465
256   K         1.315   1.325   1.355   1.273   1.284   1.340   1.409   1.422   1.465
257   P         1.315   1.325   1.355   1.498   1.514   1.556   1.409   1.422   1.465
258   Q        -0.074  -0.092  -0.030  -0.120  -0.161  -0.076  -0.338  -0.369  -0.277
259   H        -0.863  -0.881  -0.810  -0.842  -0.862  -0.759  -0.920  -0.931  -0.828
260   I        -0.074  -0.092  -0.030  -0.188  -0.211  -0.101  -0.338  -0.369  -0.277
261   G         1.315   1.325   1.355   1.248   1.268   1.317   1.409   1.422   1.465
262   E         1.315   1.325   1.355   1.372   1.385   1.435   1.409   1.422   1.465
263   L        -0.074  -0.092  -0.030  -0.316  -0.333  -0.221  -0.338  -0.369  -0.277
264   I        -0.074  -0.092  -0.030  -0.300  -0.337  -0.228  -0.338  -0.369  -0.277
265   R         1.315   1.325   1.355   1.431   1.450   1.492   1.409   1.422   1.465
266   I         1.315   1.325   1.355   1.248   1.261   1.317   1.409   1.422   1.465
267   N        -0.074  -0.092  -0.030  -0.241  -0.270  -0.165  -0.338  -0.369  -0.277
268   D        -0.074  -0.092  -0.030  -0.265  -0.304  -0.202  -0.338  -0.369  -0.277
269   N        -0.863  -0.843  -0.829  -1.003  -0.964  -0.932  -0.920  -0.888  -0.849
270   G         0.282   0.240   0.085   0.270   0.214  -0.039   0.244   0.179  -0.081
271   G         1.315   1.325   1.355   1.248   1.268   1.317   1.409   1.422   1.465
272   T        -0.074  -0.092  -0.030  -0.122  -0.148  -0.052  -0.338  -0.369  -0.277
273   V         0.282   0.240   0.085   0.314   0.251  -0.003   0.244   0.179  -0.081
274   S        -0.647  -0.725  -0.792  -0.675  -0.800  -0.936  -0.629  -0.724  -0.802
275   L        -0.074  -0.092  -0.030  -0.415  -0.445  -0.332  -0.338  -0.369  -0.277
276   G         0.282   0.240   0.085   0.270   0.214  -0.039   0.244   0.179  -0.081
277   R         1.315   1.325   1.355   1.431   1.450   1.492   1.409   1.422   1.465
278   V         0.282   0.240   0.085   0.314   0.251  -0.003   0.244   0.179  -0.081
279   G        -0.074  -0.092  -0.030  -0.318  -0.348  -0.248  -0.338  -0.369  -0.277
280   G        -0.074  -0.092  -0.030  -0.257  -0.283  -0.178  -0.338  -0.369  -0.277
281   V         0.282   0.230   0.085   0.314   0.235  -0.003   0.244   0.163  -0.081
282   L         1.315   1.325   1.355   1.137   1.150   1.210   1.409   1.422   1.465
283   A         1.315   1.325   1.355   1.369   1.385   1.432   1.409   1.422   1.465
284   L         1.315   1.325   1.355   1.137   1.150   1.210   1.409   1.422   1.465
285   S         1.315   1.325   1.355   1.261   1.280   1.328   1.409   1.422   1.465
286   R         1.315   1.325   1.355   1.431   1.450   1.492   1.409   1.422   1.465
287   A         1.315   1.325   1.355   1.369   1.385   1.432   1.409   1.422   1.465
288   F         1.315   1.325   1.355   1.396   1.414   1.458   1.409   1.422   1.465
289   S        -0.074  -0.020   0.004  -0.321  -0.217  -0.189  -0.338  -0.245  -0.219
290   D         1.315   1.325   1.355   1.309   1.322   1.375   1.409   1.422   1.465
291   F         1.315   1.325   1.355   1.396   1.414   1.458   1.409   1.422   1.465
292   Q        -0.074  -0.092  -0.030  -0.114  -0.158  -0.068  -0.338  -0.369  -0.277
293   F         1.315   1.325   1.355   1.396   1.414   1.458   1.409   1.422   1.465
294   K         1.315   1.325   1.355   1.273   1.284   1.340   1.409   1.422   1.465
295   R        -0.074  -0.092  -0.030  -0.231  -0.283  -0.191  -0.338  -0.369  -0.277
296   G        -0.863  -0.843  -0.829  -0.859  -0.802  -0.801  -0.920  -0.888  -0.849
297   V        -0.074  -0.092  -0.030  -0.178  -0.204  -0.100  -0.338  -0.369  -0.277
298   T        -2.007  -1.987  -1.873  -1.858  -1.828  -1.656  -1.503  -1.475  -1.337
299   Y        -0.647  -0.725  -0.792  -0.445  -0.567  -0.704  -0.629  -0.724  -0.802
300   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
301   P        -1.547  -1.486  -1.425  -1.432  -1.385  -1.248  -1.321  -1.253  -1.162
302   H        -0.647  -0.627  -0.752  -0.578  -0.552  -0.732  -0.629  -0.602  -0.752
303   R        -2.007  -1.987  -1.873  -1.913  -1.889  -1.708  -1.503  -1.475  -1.337
304   R        -0.863  -0.881  -0.813  -0.820  -0.826  -0.713  -0.920  -0.931  -0.830
305   T        -0.863  -0.814  -0.824  -0.861  -0.798  -0.770  -0.920  -0.860  -0.844
306   K        -0.647  -0.585  -0.745  -0.600  -0.518  -0.754  -0.629  -0.546  -0.743
307   L        -1.435  -1.354  -1.402  -1.247  -1.109  -1.220  -1.211  -1.120  -1.141
308   T        -0.647  -0.585  -0.744  -0.615  -0.525  -0.760  -0.629  -0.546  -0.741
309   N        -1.435  -1.447  -1.402  -1.407  -1.419  -1.355  -1.211  -1.215  -1.141
310   I        -1.435  -1.417  -1.378  -1.328  -1.294  -1.252  -1.211  -1.185  -1.118
311   T        -0.647  -0.585  -0.744  -0.605  -0.511  -0.755  -0.629  -0.546  -0.741
312   Q        -1.435  -1.422  -1.379  -1.206  -1.181  -1.142  -1.211  -1.191  -1.119
313   N        -0.074  -0.020   0.004  -0.297  -0.200  -0.165  -0.338  -0.245  -0.219
314   L        -0.863  -0.818  -0.805  -0.912  -0.848  -0.801  -0.920  -0.866  -0.823
315   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
316   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
317   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
318   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
319   T        -0.831  -0.792  -0.822  -1.011  -0.946  -0.983  -0.866  -0.809  -0.839
320   Y        -0.831  -0.792  -0.822  -0.874  -0.811  -0.851  -0.866  -0.809  -0.839
321   G        -1.547  -1.535  -1.425  -1.356  -1.328  -1.175  -1.321  -1.299  -1.162
322   T        -0.863  -0.843  -0.829  -1.043  -1.024  -0.984  -0.920  -0.888  -0.849
323   P         1.315   1.325   1.355   1.498   1.514   1.556   1.409   1.422   1.465
324   P         0.282   0.292   0.095   0.541   0.558   0.243   0.244   0.260  -0.064
325   Q        -0.074  -0.020   0.004  -0.089  -0.001   0.034  -0.338  -0.245  -0.219
326   E        -0.074  -0.092  -0.030  -0.284  -0.338  -0.237  -0.338  -0.369  -0.277
327   A        -0.074  -0.092  -0.030  -0.140  -0.170  -0.074  -0.338  -0.369  -0.277
328   Q         0.282   0.230   0.085   0.469   0.392   0.114   0.244   0.163  -0.081
329   V         1.315   1.325   1.355   1.297   1.311   1.363   1.409   1.422   1.465
330   T        -0.074  -0.065  -0.028  -0.222  -0.202  -0.162  -0.338  -0.323  -0.275
331   V         1.315   1.325   1.355   1.297   1.311   1.363   1.409   1.422   1.465
332   E         1.315   1.325   1.355   1.372   1.385   1.435   1.409   1.422   1.465
333   P         1.315   1.325   1.355   1.498   1.514   1.556   1.409   1.422   1.465
334   D         1.315   1.325   1.355   1.309   1.322   1.375   1.409   1.422   1.465
335   V         0.282   0.240   0.085   0.314   0.251  -0.003   0.244   0.179  -0.081
336   L        -0.647  -0.725  -0.792  -0.678  -0.788  -0.858  -0.629  -0.724  -0.802
337   M        -1.435  -1.476  -1.413  -1.205  -1.290  -1.210  -1.211  -1.243  -1.151
338   H        -0.074  -0.092  -0.030  -0.042  -0.074   0.017  -0.338  -0.369  -0.277
339   K        -0.863  -0.843  -0.829  -0.942  -0.907  -0.866  -0.920  -0.888  -0.849
340   I        -0.863  -0.877  -0.812  -1.037  -1.049  -0.922  -0.920  -0.926  -0.829
341   D        -0.647  -0.725  -0.792  -0.527  -0.643  -0.744  -0.629  -0.724  -0.802
342   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
343   Y        -0.647  -0.532  -0.747  -0.663  -0.505  -0.779  -0.629  -0.477  -0.746
344   S        -1.435  -1.447  -1.400  -1.433  -1.450  -1.381  -1.211  -1.215  -1.139
345   K        -0.863  -0.872  -0.812  -0.857  -0.851  -0.763  -0.920  -0.919  -0.829
346   D        -0.074  -0.092  -0.030  -0.132  -0.156  -0.051  -0.338  -0.369  -0.277
347   E         1.315   1.325   1.355   1.372   1.385   1.435   1.409   1.422   1.465
348   F         1.315   1.325   1.355   1.396   1.414   1.458   1.409   1.422   1.465
349   L         0.282   0.230   0.085   0.167   0.091  -0.124   0.244   0.163  -0.081
350   V         1.315   1.325   1.355   1.297   1.311   1.363   1.409   1.422   1.465
351   L         0.282   0.240   0.085   0.155   0.091  -0.146   0.244   0.179  -0.081
352   A         1.315   1.325   1.355   1.369   1.385   1.432   1.409   1.422   1.465
353   C         1.315   1.325   1.355   1.545   1.560   1.600   1.409   1.422   1.465
354   D         1.315   1.325   1.355   1.309   1.322   1.375   1.409   1.422   1.465
355   G         1.315   1.325   1.355   1.248   1.268   1.317   1.409   1.422   1.465
356   I         0.282   0.240   0.085   0.277   0.215  -0.025   0.244   0.179  -0.081
357   W         1.315   1.325   1.355   1.599   1.615   1.653   1.409   1.422   1.465
358   D         1.315   1.325   1.355   1.309   1.322   1.375   1.409   1.422   1.465
359   I        -0.863  -0.843  -0.829  -0.816  -0.761  -0.756  -0.920  -0.888  -0.849
360   Y         0.282   0.240   0.085   0.487   0.430   0.183   0.244   0.179  -0.081
361   N        -1.435  -1.476  -1.413  -1.407  -1.464  -1.372  -1.211  -1.243  -1.151
362   N         1.315   1.325   1.355   1.267   1.284   1.334   1.409   1.422   1.465
363   K        -0.863  -0.877  -0.812  -0.946  -0.960  -0.857  -0.920  -0.926  -0.829
364   Q        -1.435  -1.422  -1.379  -1.159  -1.143  -1.091  -1.211  -1.191  -1.119
365   L         1.315   1.325   1.355   1.137   1.150   1.210   1.409   1.422   1.465
366   I        -0.074  -0.078  -0.031  -0.300  -0.313  -0.229  -0.338  -0.346  -0.279
367   H        -1.435  -1.354  -1.402  -1.272  -1.163  -1.203  -1.211  -1.120  -1.141
368   F        -0.647  -0.725  -0.792  -0.560  -0.693  -0.851  -0.629  -0.724  -0.802
369   I         1.315   1.325   1.355   1.248   1.261   1.317   1.409   1.422   1.465
370   K        -0.074  -0.092  -0.030  -0.201  -0.227  -0.122  -0.338  -0.369  -0.277
371   Y        -0.074  -0.092  -0.030  -0.131  -0.174  -0.078  -0.338  -0.369  -0.277
372   H        -0.074  -0.092  -0.030  -0.134  -0.179  -0.086  -0.338  -0.369  -0.277
373   L         1.315   1.325   1.355   1.137   1.150   1.210   1.409   1.422   1.465
374   V        -1.435  -1.354  -1.402  -1.305  -1.186  -1.238  -1.211  -1.120  -1.141
375   S        -0.647  -0.532  -0.747  -0.693  -0.529  -0.819  -0.629  -0.477  -0.746
376   G         0.282   0.230   0.085   0.280   0.210  -0.020   0.244   0.163  -0.081
377   T        -1.435  -1.354  -1.402  -1.095  -0.962  -1.090  -1.211  -1.120  -1.141
378   K         0.282   0.240   0.085   0.335   0.277   0.055   0.244   0.179  -0.081
379   L         0.282   0.230   0.085   0.155   0.076  -0.146   0.244   0.163  -0.081
380   D        -0.647  -0.725  -0.792  -0.536  -0.651  -0.758  -0.629  -0.724  -0.802
381   T        -2.007  -1.987  -1.873  -1.835  -1.791  -1.633  -1.503  -1.475  -1.337
382   I         1.315   1.325   1.355   1.248   1.261   1.317   1.409   1.422   1.465
383   I        -2.007  -1.987  -1.873  -1.871  -1.844  -1.668  -1.503  -1.475  -1.337
384   T        -0.863  -0.843  -0.829  -0.834  -0.797  -0.770  -0.920  -0.888  -0.849
385   K        -0.647  -0.725  -0.792  -0.536  -0.648  -0.735  -0.629  -0.724  -0.802
386   L        -0.074  -0.020   0.004  -0.393  -0.289  -0.257  -0.338  -0.245  -0.219
387   L         1.315   1.325   1.355   1.137   1.150   1.210   1.409   1.422   1.465
388   D        -0.074  -0.092  -0.030  -0.265  -0.304  -0.202  -0.338  -0.369  -0.277
389   H        -0.074  -0.092  -0.030  -0.114  -0.155  -0.063  -0.338  -0.369  -0.277
390   G        -0.647  -0.725  -0.792  -0.567  -0.669  -0.764  -0.629  -0.724  -0.802
391   I        -0.647  -0.725  -0.792  -0.687  -0.818  -0.946  -0.629  -0.724  -0.802
392   A        -1.435  -1.476  -1.413  -1.331  -1.394  -1.318  -1.211  -1.243  -1.151
393   Q        -0.863  -0.843  -0.829  -0.614  -0.578  -0.546  -0.920  -0.888  -0.849
394   A         1.315   1.325   1.355   1.369   1.385   1.432   1.409   1.422   1.465
395   N         0.282   0.292   0.095   0.299   0.316   0.014   0.244   0.260  -0.064
396   S        -0.074  -0.092  -0.030  -0.307  -0.339  -0.238  -0.338  -0.369  -0.277
397   N        -1.435  -1.447  -1.400  -1.365  -1.373  -1.305  -1.211  -1.215  -1.139
398   T         1.315   1.325   1.355   1.363   1.382   1.426   1.409   1.422   1.465
399   G         1.315   1.325   1.355   1.248   1.268   1.317   1.409   1.422   1.465
400   V        -0.074  -0.092  -0.030  -0.286  -0.328  -0.223  -0.338  -0.369  -0.277
401   G         1.315   1.325   1.355   1.248   1.268   1.317   1.409   1.422   1.465
402   F         1.315   1.325   1.355   1.396   1.414   1.458   1.409   1.422   1.465
403   D         1.315   1.325   1.355   1.309   1.322   1.375   1.409   1.422   1.465
404   N         1.315   1.325   1.355   1.267   1.284   1.334   1.409   1.422   1.465
405   M         0.282   0.292   0.095   0.539   0.554   0.246   0.244   0.260  -0.064
406   T         1.315   1.325   1.355   1.363   1.382   1.426   1.409   1.422   1.465
407   A        -0.863  -0.877  -0.813  -1.038  -1.068  -0.962  -0.920  -0.925  -0.830
408   I         1.315   1.325   1.355   1.248   1.261   1.317   1.409   1.422   1.465
409   I        -0.074  -0.044  -0.010  -0.300  -0.250  -0.193  -0.338  -0.286  -0.243
410   V         1.315   1.325   1.355   1.297   1.311   1.363   1.409   1.422   1.465
411   V        -0.074  -0.092  -0.030  -0.217  -0.247  -0.144  -0.338  -0.369  -0.277
412   L        -0.647  -0.725  -0.792  -0.759  -0.881  -0.979  -0.629  -0.724  -0.802
413   N        -0.863  -0.843  -0.829  -0.801  -0.747  -0.718  -0.920  -0.888  -0.849
414   R        -1.435  -1.476  -1.413  -1.219  -1.289  -1.206  -1.211  -1.243  -1.151
415   K        -0.863  -0.881  -0.813  -0.842  -0.874  -0.774  -0.920  -0.931  -0.830
416   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
417   G         0.154   0.269   0.061   0.086   0.268  -0.065   0.044   0.225  -0.122
418   E         0.282   0.230   0.085   0.392   0.314   0.071   0.244   0.163  -0.081
419   T        -0.647  -0.635  -0.750  -0.548  -0.526  -0.733  -0.629  -0.613  -0.749
420   L        -0.647  -0.725  -0.792  -0.694  -0.807  -0.881  -0.629  -0.724  -0.802
421   Q        -0.647  -0.532  -0.747  -0.469  -0.311  -0.597  -0.629  -0.477  -0.746
422   D        -0.074  -0.081  -0.031  -0.205  -0.221  -0.135  -0.338  -0.350  -0.279
423   W         1.315   1.325   1.355   1.599   1.615   1.653   1.409   1.422   1.465
424   F        -0.647  -0.532  -0.747  -0.368  -0.204  -0.519  -0.629  -0.477  -0.746
425   N        -1.435  -1.476  -1.413  -1.320  -1.371  -1.269  -1.211  -1.243  -1.151
426   K        -1.435  -1.476  -1.413  -1.282  -1.334  -1.226  -1.211  -1.243  -1.151
427   M         0.282   0.292   0.095   0.504   0.517   0.187   0.244   0.260  -0.064
428   K         1.315   1.325   1.355   1.273   1.284   1.340   1.409   1.422   1.465
429   T        -1.435  -1.354  -1.402  -1.374  -1.234  -1.349  -1.211  -1.120  -1.141
430   R         0.282   0.240   0.085   0.452   0.394   0.126   0.244   0.179  -0.081
431   L        -0.647  -0.725  -0.792  -0.759  -0.881  -0.979  -0.629  -0.724  -0.802
432   E        -0.074  -0.092  -0.030  -0.284  -0.338  -0.237  -0.338  -0.369  -0.277
433   R        -0.074  -0.092  -0.030  -0.156  -0.199  -0.106  -0.338  -0.369  -0.277
434   E         1.315   1.325   1.355   1.372   1.385   1.435   1.409   1.422   1.465
435   R         0.282   0.356   0.102   0.335   0.433   0.082   0.244   0.356  -0.052
436   G         1.315   1.325   1.355   1.248   1.268   1.317   1.409   1.422   1.465
437   L        -0.074  -0.062  -0.029  -0.426  -0.409  -0.343  -0.338  -0.317  -0.275
438   V        -1.435  -1.383  -1.378  -1.512  -1.431  -1.409  -1.211  -1.151  -1.118
439   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P38089
Output conservation file - output/P38089
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
