1     M         1.032   1.041   1.096   1.182   1.192   1.268   1.099   1.110   1.190
2     S        -0.485  -0.607  -0.647  -0.396  -0.577  -0.655  -0.577  -0.749  -0.804
3     K        -0.629  -0.761  -0.679  -0.751  -0.964  -0.832  -0.778  -0.963  -0.847
4     T        -0.145  -0.160  -0.035  -0.329  -0.348  -0.152  -0.510  -0.547  -0.355
5     A        -0.812  -0.743  -0.674  -1.088  -0.992  -0.852  -1.047  -0.963  -0.843
6     V        -0.629  -0.761  -0.679  -0.698  -0.924  -0.793  -0.778  -0.963  -0.847
7     K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    D        -0.736  -0.727  -0.655  -1.004  -0.961  -0.877  -0.950  -0.918  -0.816
11    S         0.315   0.247   0.073   0.378   0.287  -0.013   0.278   0.169  -0.156
12    A         1.032   1.041   1.096   1.084   1.091   1.180   1.099   1.110   1.190
13    T         0.244   0.098   0.033   0.271   0.045  -0.090   0.167  -0.078  -0.227
14    E        -0.736  -0.693  -0.670  -0.906  -0.844  -0.779  -0.950  -0.906  -0.837
15    K         1.032   1.041   1.096   0.918   0.931   1.029   1.099   1.110   1.190
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    T        -1.677  -1.644  -1.506  -1.759  -1.742  -1.488  -1.501  -1.464  -1.263
18    K        -1.391  -1.166  -1.454  -1.188  -0.869  -1.303  -1.206  -0.964  -1.216
19    L        -0.254  -0.400  -0.594  -0.209  -0.400  -0.670  -0.263  -0.463  -0.733
20    S        -1.694  -1.707  -1.513  -1.659  -1.688  -1.425  -1.520  -1.511  -1.269
21    E        -2.300  -2.287  -2.074  -2.064  -2.048  -1.741  -1.730  -1.706  -1.456
22    S        -1.694  -1.629  -1.513  -1.655  -1.560  -1.384  -1.520  -1.452  -1.269
23    E         0.373   0.260   0.092   0.415   0.263  -0.027   0.365   0.190  -0.121
24    Q         0.373   0.260   0.092   0.592   0.433   0.118   0.365   0.190  -0.121
25    H         0.373   0.260   0.092   0.605   0.454   0.174   0.365   0.190  -0.121
26    Y         1.032   1.041   1.096   1.087   1.099   1.182   1.099   1.110   1.190
27    F         1.032   1.041   1.096   1.074   1.087   1.170   1.099   1.110   1.190
28    N        -1.277  -1.273  -1.143  -1.358  -1.343  -1.162  -1.311  -1.287  -1.106
29    S         1.032   1.041   1.096   1.043   1.058   1.142   1.099   1.110   1.190
30    Y         1.032   1.041   1.096   1.087   1.099   1.182   1.099   1.110   1.190
31    D        -0.254  -0.400  -0.594  -0.237  -0.434  -0.709  -0.263  -0.463  -0.733
32    H         1.032   1.041   1.096   1.181   1.190   1.267   1.099   1.110   1.190
33    Y        -1.088  -1.132  -1.111  -0.940  -0.967  -0.931  -1.101  -1.128  -1.072
34    G         1.032   1.041   1.096   1.058   1.071   1.156   1.099   1.110   1.190
35    I         1.032   1.041   1.096   0.977   0.989   1.082   1.099   1.110   1.190
36    H         1.032   1.041   1.096   1.181   1.190   1.267   1.099   1.110   1.190
37    E         1.032   1.041   1.096   1.012   1.026   1.114   1.099   1.110   1.190
38    E         1.032   1.041   1.096   1.012   1.026   1.114   1.099   1.110   1.190
39    M         1.032   1.041   1.096   1.182   1.192   1.268   1.099   1.110   1.190
40    L         1.032   1.041   1.096   0.919   0.935   1.030   1.099   1.110   1.190
41    Q        -0.125  -0.030   0.005  -0.341  -0.188  -0.128  -0.473  -0.304  -0.279
42    D         1.032   1.041   1.096   0.902   0.912   1.014   1.099   1.110   1.190
43    T        -0.542  -0.666  -0.650  -0.594  -0.800  -0.809  -0.682  -0.845  -0.812
44    V        -0.125  -0.111  -0.024  -0.369  -0.349  -0.211  -0.473  -0.455  -0.333
45    R         1.032   1.041   1.096   1.177   1.183   1.263   1.099   1.110   1.190
46    T         1.032   1.041   1.096   1.040   1.053   1.139   1.099   1.110   1.190
47    L         0.373   0.332   0.098   0.321   0.271  -0.096   0.365   0.301  -0.111
48    S         1.032   1.041   1.096   1.043   1.058   1.142   1.099   1.110   1.190
49    Y         1.032   1.041   1.096   1.087   1.099   1.182   1.099   1.110   1.190
50    R        -0.254  -0.334  -0.583   0.026  -0.088  -0.498  -0.263  -0.372  -0.718
51    N        -1.088  -1.170  -1.128  -0.955  -1.092  -1.055  -1.101  -1.190  -1.090
52    A         0.373   0.332   0.098   0.502   0.445   0.086   0.365   0.301  -0.111
53    I         0.049   0.085   0.034  -0.028   0.026  -0.055  -0.158  -0.101  -0.227
54    I        -1.997  -1.997  -1.821  -1.924  -1.915  -1.664  -1.625  -1.609  -1.380
55    Q        -0.542  -0.526  -0.636  -0.382  -0.366  -0.574  -0.682  -0.665  -0.793
56    N         1.032   1.041   1.096   1.134   1.152   1.224   1.099   1.110   1.190
57    K        -0.254  -0.398  -0.587  -0.178  -0.360  -0.608  -0.263  -0.460  -0.723
58    D        -0.125  -0.143  -0.033  -0.374  -0.401  -0.202  -0.473  -0.515  -0.352
59    L        -0.254  -0.077  -0.555  -0.207   0.014  -0.605  -0.263  -0.031  -0.678
60    F         1.032   1.041   1.096   1.074   1.087   1.170   1.099   1.110   1.190
61    K         0.373   0.260   0.092   0.370   0.232  -0.001   0.365   0.190  -0.121
62    D         0.373   0.475   0.110   0.322   0.444  -0.042   0.365   0.509  -0.088
63    K         1.032   1.041   1.096   0.932   0.948   1.041   1.099   1.110   1.190
64    I        -0.125  -0.052  -0.011  -0.410  -0.276  -0.228  -0.473  -0.344  -0.309
65    V         1.032   1.041   1.096   0.994   1.005   1.097   1.099   1.110   1.190
66    L         1.032   1.041   1.096   0.919   0.935   1.030   1.099   1.110   1.190
67    D         1.032   1.041   1.096   0.902   0.912   1.014   1.099   1.110   1.190
68    V         1.032   1.041   1.096   0.994   1.005   1.097   1.099   1.110   1.190
69    G         1.032   1.041   1.096   1.058   1.071   1.156   1.099   1.110   1.190
70    C         1.032   1.041   1.096   1.262   1.269   1.340   1.099   1.110   1.190
71    G         1.032   1.041   1.096   1.058   1.071   1.156   1.099   1.110   1.190
72    T         1.032   1.041   1.096   1.040   1.053   1.139   1.099   1.110   1.190
73    G         1.032   1.041   1.096   1.058   1.071   1.156   1.099   1.110   1.190
74    I         1.032   1.041   1.096   0.977   0.989   1.082   1.099   1.110   1.190
75    L         1.032   1.041   1.096   0.919   0.935   1.030   1.099   1.110   1.190
76    S         1.032   1.041   1.096   1.043   1.058   1.142   1.099   1.110   1.190
77    M         1.032   1.041   1.096   1.182   1.192   1.268   1.099   1.110   1.190
78    F         1.032   1.041   1.096   1.074   1.087   1.170   1.099   1.110   1.190
79    A         0.373   0.260   0.092   0.533   0.390   0.157   0.365   0.190  -0.121
80    A         0.049   0.085   0.034   0.013   0.066  -0.054  -0.158  -0.101  -0.227
81    K        -0.254  -0.398  -0.587  -0.174  -0.355  -0.600  -0.263  -0.460  -0.723
82    H        -0.542  -0.373  -0.607  -0.455  -0.215  -0.538  -0.682  -0.446  -0.752
83    G         1.032   1.041   1.096   1.058   1.071   1.156   1.099   1.110   1.190
84    A         1.032   1.041   1.096   1.083   1.090   1.179   1.099   1.110   1.190
85    K         1.032   1.041   1.096   0.932   0.948   1.041   1.099   1.110   1.190
86    H         1.032   1.041   1.096   1.181   1.190   1.267   1.099   1.110   1.190
87    V         1.032   1.041   1.096   0.994   1.005   1.097   1.099   1.110   1.190
88    I        -0.671  -0.694  -0.655  -0.796  -0.816  -0.708  -0.892  -0.913  -0.820
89    G         0.049   0.085   0.034   0.004   0.063  -0.052  -0.158  -0.101  -0.227
90    V         1.032   1.041   1.096   0.994   1.005   1.097   1.099   1.110   1.190
91    D         1.032   1.041   1.096   0.902   0.912   1.014   1.099   1.110   1.190
92    M         1.032   1.041   1.096   1.182   1.192   1.268   1.099   1.110   1.190
93    S         1.032   1.041   1.096   1.043   1.058   1.142   1.099   1.110   1.190
94    S        -1.088  -1.195  -1.127  -1.033  -1.187  -1.096  -1.101  -1.209  -1.090
95    I         1.032   1.041   1.096   0.977   0.989   1.082   1.099   1.110   1.190
96    I         1.032   1.041   1.096   0.977   0.989   1.082   1.099   1.110   1.190
97    E        -1.391  -1.462  -1.489  -1.231  -1.331  -1.399  -1.206  -1.276  -1.248
98    M        -0.180  -0.151  -0.031  -0.414  -0.381  -0.180  -0.577  -0.530  -0.347
99    A         1.032   1.041   1.096   1.083   1.090   1.179   1.099   1.110   1.190
100   K        -0.671  -0.736  -0.652  -0.815  -0.893  -0.744  -0.892  -0.955  -0.817
101   E        -1.088  -1.060  -1.106  -1.031  -1.001  -1.047  -1.101  -1.075  -1.069
102   L         0.049   0.156   0.049  -0.115   0.062  -0.145  -0.158   0.019  -0.199
103   V         1.032   1.041   1.096   0.994   1.005   1.097   1.099   1.110   1.190
104   E        -0.845  -0.900  -1.081  -0.753  -0.841  -1.171  -0.787  -0.852  -1.038
105   L         0.049  -0.030  -0.004  -0.147  -0.287  -0.260  -0.158  -0.305  -0.297
106   N         1.032   1.041   1.096   1.134   1.152   1.224   1.099   1.110   1.190
107   G         0.373   0.260   0.092   0.461   0.308   0.013   0.365   0.190  -0.121
108   F        -0.180  -0.151  -0.030  -0.504  -0.461  -0.257  -0.577  -0.529  -0.346
109   S         0.373   0.398   0.105   0.457   0.493   0.054   0.365   0.400  -0.097
110   D         1.032   1.041   1.096   0.902   0.912   1.014   1.099   1.110   1.190
111   K         0.373   0.260   0.092   0.370   0.232  -0.001   0.365   0.190  -0.121
112   I         1.032   1.041   1.096   0.977   0.989   1.082   1.099   1.110   1.190
113   T         1.032   1.041   1.096   1.040   1.053   1.139   1.099   1.110   1.190
114   L         1.032   1.041   1.096   0.919   0.935   1.030   1.099   1.110   1.190
115   L        -0.125  -0.151  -0.034  -0.471  -0.528  -0.324  -0.473  -0.531  -0.352
116   R        -0.125  -0.030   0.005  -0.125   0.039   0.064  -0.473  -0.304  -0.279
117   G         1.032   1.041   1.096   1.058   1.071   1.156   1.099   1.110   1.190
118   K         1.032   1.041   1.096   0.932   0.948   1.041   1.099   1.110   1.190
119   L        -0.125  -0.151  -0.034  -0.358  -0.391  -0.190  -0.473  -0.531  -0.352
120   E         1.032   1.041   1.096   1.012   1.026   1.114   1.099   1.110   1.190
121   D        -0.125  -0.151  -0.034  -0.467  -0.521  -0.313  -0.473  -0.531  -0.352
122   V        -0.125  -0.030   0.005  -0.410  -0.235  -0.196  -0.473  -0.304  -0.279
123   H        -1.883  -1.843  -1.785  -1.643  -1.586  -1.501  -1.520  -1.482  -1.354
124   L         1.032   1.041   1.096   0.919   0.935   1.030   1.099   1.110   1.190
125   P         1.032   1.041   1.096   1.172   1.180   1.259   1.099   1.110   1.190
126   F        -0.860  -0.824  -0.692  -1.059  -1.008  -0.794  -1.101  -1.053  -0.864
127   P        -1.580  -1.610  -1.496  -1.491  -1.527  -1.397  -1.415  -1.427  -1.255
128   K         0.373   0.398   0.105   0.346   0.382  -0.042   0.365   0.400  -0.097
129   V         1.032   1.041   1.096   0.994   1.005   1.097   1.099   1.110   1.190
130   D         1.032   1.041   1.096   0.902   0.912   1.014   1.099   1.110   1.190
131   I         1.032   1.041   1.096   0.977   0.989   1.082   1.099   1.110   1.190
132   I         1.032   1.041   1.096   0.977   0.989   1.082   1.099   1.110   1.190
133   I         0.049  -0.000  -0.007  -0.090  -0.181  -0.220  -0.158  -0.251  -0.302
134   S         1.032   1.041   1.096   1.043   1.058   1.142   1.099   1.110   1.190
135   E         1.032   1.041   1.096   1.012   1.026   1.114   1.099   1.110   1.190
136   W         1.032   1.041   1.096   1.260   1.268   1.339   1.099   1.110   1.190
137   M         1.032   1.041   1.096   1.182   1.192   1.268   1.099   1.110   1.190
138   G         1.032   1.041   1.096   1.058   1.071   1.156   1.099   1.110   1.190
139   Y         1.032   1.041   1.096   1.087   1.099   1.182   1.099   1.110   1.190
140   F         1.032   1.041   1.096   1.074   1.087   1.170   1.099   1.110   1.190
141   L         1.032   1.041   1.096   0.919   0.935   1.030   1.099   1.110   1.190
142   L         1.032   1.041   1.096   0.919   0.935   1.030   1.099   1.110   1.190
143   Y         1.032   1.041   1.096   1.087   1.099   1.182   1.099   1.110   1.190
144   E         1.032   1.041   1.096   1.012   1.026   1.114   1.099   1.110   1.190
145   S         1.032   1.041   1.096   1.043   1.058   1.142   1.099   1.110   1.190
146   M         1.032   1.041   1.096   1.182   1.192   1.268   1.099   1.110   1.190
147   M         0.373   0.457   0.111   0.358   0.462   0.020   0.365   0.485  -0.087
148   D         1.032   1.041   1.096   0.902   0.912   1.014   1.099   1.110   1.190
149   T         1.032   1.041   1.096   1.040   1.053   1.139   1.099   1.110   1.190
150   V         1.032   1.041   1.096   0.994   1.005   1.097   1.099   1.110   1.190
151   L         1.032   1.041   1.096   0.919   0.935   1.030   1.099   1.110   1.190
152   Y         0.373   0.260   0.092   0.499   0.347   0.060   0.365   0.190  -0.121
153   A         1.032   1.041   1.096   1.083   1.090   1.179   1.099   1.110   1.190
154   R         1.032   1.041   1.096   1.177   1.183   1.263   1.099   1.110   1.190
155   D         1.032   1.041   1.096   0.902   0.912   1.014   1.099   1.110   1.190
156   H        -1.088  -0.962  -1.094  -0.944  -0.794  -0.959  -1.101  -0.972  -1.056
157   Y         1.032   1.041   1.096   1.087   1.099   1.182   1.099   1.110   1.190
158   L         1.032   1.041   1.096   0.919   0.935   1.030   1.099   1.110   1.190
159   V         0.049  -0.030  -0.004  -0.045  -0.185  -0.154  -0.158  -0.305  -0.297
160   E        -0.125  -0.151  -0.034  -0.284  -0.328  -0.134  -0.473  -0.531  -0.352
161   G         0.373   0.260   0.092   0.457   0.301   0.002   0.365   0.190  -0.121
162   G         1.032   1.041   1.096   1.058   1.071   1.156   1.099   1.110   1.190
163   L         0.373   0.334   0.099   0.328   0.281  -0.076   0.365   0.304  -0.108
164   I         0.373   0.260   0.092   0.378   0.223  -0.062   0.365   0.190  -0.121
165   F        -0.254  -0.274  -0.571  -0.078  -0.101  -0.563  -0.263  -0.291  -0.701
166   P         1.032   1.041   1.096   1.172   1.180   1.259   1.099   1.110   1.190
167   D         1.032   1.041   1.096   0.902   0.912   1.014   1.099   1.110   1.190
168   K         0.373   0.260   0.092   0.370   0.232  -0.001   0.365   0.190  -0.121
169   C        -0.542  -0.637  -0.651  -0.333  -0.512  -0.564  -0.682  -0.821  -0.812
170   S        -0.786  -0.827  -0.690  -0.866  -0.932  -0.721  -0.996  -1.052  -0.862
171   I         0.049   0.085   0.034  -0.028   0.026  -0.055  -0.158  -0.101  -0.227
172   H        -1.163  -1.222  -1.135  -1.042  -1.109  -0.976  -1.206  -1.244  -1.098
173   L        -1.088  -1.065  -1.107  -1.187  -1.169  -1.216  -1.101  -1.081  -1.070
174   A         1.032   1.041   1.096   1.083   1.090   1.179   1.099   1.110   1.190
175   G        -0.254  -0.398  -0.587  -0.111  -0.311  -0.641  -0.263  -0.460  -0.723
176   L        -0.180  -0.151  -0.031  -0.577  -0.519  -0.314  -0.577  -0.530  -0.347
177   E         1.032   1.041   1.096   1.012   1.026   1.114   1.099   1.110   1.190
178   D         1.032   1.041   1.096   0.902   0.912   1.014   1.099   1.110   1.190
179   S        -0.786  -0.737  -0.665  -0.888  -0.818  -0.722  -0.996  -0.935  -0.829
180   Q        -1.088  -1.091  -1.124  -1.024  -1.085  -1.156  -1.101  -1.121  -1.087
181   Y         1.032   1.041   1.096   1.087   1.099   1.182   1.099   1.110   1.190
182   K         1.032   1.041   1.096   0.932   0.948   1.041   1.099   1.110   1.190
183   D        -0.845  -0.843  -1.069  -0.817  -0.827  -1.146  -0.787  -0.793  -1.025
184   E         1.032   1.041   1.096   1.012   1.026   1.114   1.099   1.110   1.190
185   K         1.032   1.041   1.096   0.932   0.948   1.041   1.099   1.110   1.190
186   L        -0.542  -0.486  -0.606  -0.673  -0.561  -0.781  -0.682  -0.587  -0.751
187   N        -1.277  -1.289  -1.153  -1.222  -1.246  -1.050  -1.311  -1.313  -1.116
188   Y        -0.180  -0.151  -0.030  -0.382  -0.332  -0.140  -0.577  -0.529  -0.346
189   W         1.032   1.041   1.096   1.260   1.268   1.339   1.099   1.110   1.190
190   Q        -1.277  -1.143  -1.137  -1.377  -1.211  -1.124  -1.311  -1.163  -1.099
191   D         0.373   0.332   0.098   0.334   0.283  -0.034   0.365   0.301  -0.111
192   V         1.032   1.041   1.096   0.994   1.005   1.097   1.099   1.110   1.190
193   Y         1.032   1.041   1.096   1.087   1.099   1.182   1.099   1.110   1.190
194   G         1.032   1.041   1.096   1.058   1.071   1.156   1.099   1.110   1.190
195   F         1.032   1.041   1.096   1.074   1.087   1.170   1.099   1.110   1.190
196   D         1.032   1.041   1.096   0.902   0.912   1.014   1.099   1.110   1.190
197   Y         0.373   0.260   0.092   0.510   0.363   0.090   0.365   0.190  -0.121
198   S         0.373   0.410   0.107   0.461   0.511   0.068   0.365   0.418  -0.093
199   P         1.032   1.041   1.096   1.172   1.180   1.259   1.099   1.110   1.190
200   F        -0.254  -0.400  -0.594  -0.112  -0.323  -0.682  -0.263  -0.463  -0.733
201   V        -0.671  -0.617  -0.654  -0.933  -0.879  -0.877  -0.892  -0.841  -0.819
202   P        -1.277  -1.297  -1.150  -1.403  -1.469  -1.249  -1.311  -1.321  -1.113
203   L        -1.580  -1.636  -1.507  -1.716  -1.810  -1.603  -1.415  -1.454  -1.264
204   V        -0.671  -0.592  -0.642  -0.828  -0.728  -0.760  -0.892  -0.805  -0.805
205   L        -1.163  -1.149  -1.119  -1.173  -1.143  -1.076  -1.206  -1.185  -1.084
206   H        -1.997  -1.884  -1.804  -1.921  -1.784  -1.620  -1.625  -1.530  -1.369
207   E         1.032   1.041   1.096   1.012   1.026   1.114   1.099   1.110   1.190
208   P         1.032   1.041   1.096   1.172   1.180   1.259   1.099   1.110   1.190
209   I         0.049   0.156   0.049  -0.153   0.023  -0.168  -0.158   0.019  -0.199
210   V         1.032   1.041   1.096   0.994   1.005   1.097   1.099   1.110   1.190
211   D         1.032   1.041   1.096   0.902   0.912   1.014   1.099   1.110   1.190
212   T         1.032   1.041   1.096   1.040   1.053   1.139   1.099   1.110   1.190
213   V         1.032   1.041   1.096   0.994   1.005   1.097   1.099   1.110   1.190
214   E        -0.860  -0.803  -0.681  -1.142  -1.059  -0.850  -1.101  -1.023  -0.850
215   R        -1.163  -1.192  -1.123  -1.093  -1.131  -1.057  -1.206  -1.219  -1.087
216   N        -1.997  -1.997  -1.821  -1.767  -1.783  -1.556  -1.625  -1.609  -1.380
217   N        -1.580  -1.578  -1.495  -1.450  -1.451  -1.305  -1.415  -1.407  -1.255
218   V         0.049   0.085   0.034  -0.098  -0.039  -0.162  -0.158  -0.101  -0.227
219   N        -0.671  -0.689  -0.655  -0.774  -0.794  -0.744  -0.892  -0.904  -0.821
220   T         0.373   0.334   0.099   0.458   0.411   0.052   0.365   0.304  -0.108
221   T        -1.088  -1.135  -1.124  -1.085  -1.165  -1.176  -1.101  -1.160  -1.088
222   S        -1.580  -1.449  -1.486  -1.417  -1.246  -1.303  -1.415  -1.297  -1.247
223   D        -1.883  -1.771  -1.783  -1.535  -1.368  -1.477  -1.520  -1.414  -1.353
224   K        -1.163  -1.228  -1.116  -1.172  -1.241  -1.071  -1.206  -1.252  -1.081
225   L        -1.277  -1.289  -1.153  -1.496  -1.509  -1.283  -1.311  -1.313  -1.116
226   I        -0.860  -0.853  -0.693  -1.148  -1.141  -0.889  -1.101  -1.087  -0.865
227   E        -0.254  -0.400  -0.594  -0.167  -0.377  -0.714  -0.263  -0.463  -0.733
228   F        -0.542  -0.637  -0.651  -0.582  -0.763  -0.806  -0.682  -0.821  -0.812
229   D         1.032   1.041   1.096   0.902   0.912   1.014   1.099   1.110   1.190
230   L         0.049   0.085   0.034  -0.153  -0.091  -0.197  -0.158  -0.101  -0.227
231   N        -0.542  -0.666  -0.650  -0.471  -0.667  -0.690  -0.682  -0.845  -0.812
232   T         1.032   1.041   1.096   1.040   1.053   1.139   1.099   1.110   1.190
233   V         0.373   0.332   0.098   0.444   0.396   0.092   0.365   0.301  -0.111
234   K        -0.125  -0.134  -0.031  -0.387  -0.417  -0.261  -0.473  -0.497  -0.348
235   I        -1.163  -1.182  -1.128  -1.356  -1.367  -1.263  -1.206  -1.205  -1.091
236   S        -1.088  -0.938  -1.105  -1.047  -0.849  -1.051  -1.101  -0.936  -1.068
237   D        -0.254  -0.204  -0.575  -0.224  -0.161  -0.651  -0.263  -0.197  -0.706
238   L         1.032   1.041   1.096   0.919   0.935   1.030   1.099   1.110   1.190
239   A         0.373   0.410   0.107   0.502   0.544   0.103   0.365   0.418  -0.093
240   F        -0.254  -0.204  -0.575  -0.084  -0.017  -0.583  -0.263  -0.197  -0.706
241   K        -0.542  -0.578  -0.626  -0.604  -0.642  -0.705  -0.682  -0.712  -0.780
242   S        -1.391  -1.414  -1.482  -1.197  -1.237  -1.361  -1.206  -1.225  -1.241
243   N        -0.671  -0.702  -0.640  -0.764  -0.754  -0.669  -0.892  -0.901  -0.800
244   F         1.032   1.041   1.096   1.074   1.087   1.170   1.099   1.110   1.190
245   K        -0.860  -0.826  -0.684  -1.231  -1.162  -0.942  -1.101  -1.051  -0.854
246   L        -0.254  -0.277  -0.572  -0.256  -0.295  -0.740  -0.263  -0.306  -0.703
247   T        -1.277  -1.294  -1.146  -1.322  -1.366  -1.152  -1.311  -1.318  -1.109
248   A         1.032   1.041   1.096   1.083   1.090   1.179   1.099   1.110   1.190
249   K        -1.277  -1.318  -1.154  -1.418  -1.450  -1.192  -1.311  -1.337  -1.116
250   R        -0.542  -0.548  -0.626  -0.487  -0.494  -0.670  -0.682  -0.681  -0.777
251   Q        -1.163  -1.142  -1.119  -1.075  -1.041  -1.036  -1.206  -1.168  -1.082
252   D         1.032   1.041   1.096   0.902   0.912   1.014   1.099   1.110   1.190
253   M        -1.883  -1.769  -1.784  -1.683  -1.520  -1.577  -1.520  -1.413  -1.354
254   I        -1.088  -1.172  -1.124  -1.028  -1.148  -1.067  -1.101  -1.179  -1.086
255   N        -0.542  -0.369  -0.610  -0.390  -0.137  -0.519  -0.682  -0.444  -0.756
256   G        -0.125  -0.030   0.005  -0.282  -0.112  -0.079  -0.473  -0.304  -0.279
257   I        -1.277  -1.258  -1.144  -1.471  -1.436  -1.231  -1.311  -1.287  -1.107
258   V        -0.786  -0.811  -0.690  -1.064  -1.127  -0.936  -0.996  -1.032  -0.862
259   T        -1.694  -1.633  -1.517  -1.653  -1.552  -1.357  -1.520  -1.455  -1.272
260   W         0.373   0.410   0.107   0.684   0.727   0.268   0.365   0.418  -0.093
261   F         0.049   0.085   0.034   0.090   0.143   0.058  -0.158  -0.101  -0.227
262   D         1.032   1.041   1.096   0.902   0.912   1.014   1.099   1.110   1.190
263   I        -0.254  -0.204  -0.575  -0.134  -0.070  -0.556  -0.263  -0.197  -0.706
264   V        -0.542  -0.521  -0.621  -0.628  -0.583  -0.782  -0.682  -0.640  -0.773
265   F         1.032   1.041   1.096   1.074   1.087   1.170   1.099   1.110   1.190
266   P        -0.845  -1.007  -1.103  -0.531  -0.771  -0.964  -0.787  -0.978  -1.062
267   A        -0.542  -0.548  -0.626  -0.529  -0.537  -0.694  -0.682  -0.681  -0.777
268   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
269   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
270   G        -0.736  -0.784  -0.680  -0.775  -0.838  -0.702  -0.950  -1.007  -0.850
271   K        -1.997  -1.897  -1.807  -1.859  -1.705  -1.584  -1.625  -1.536  -1.371
272   R        -1.391  -1.326  -1.465  -1.258  -1.174  -1.341  -1.206  -1.135  -1.227
273   P        -0.254  -0.204  -0.575   0.037   0.098  -0.452  -0.263  -0.197  -0.706
274   V         0.049  -0.030  -0.004  -0.080  -0.228  -0.210  -0.158  -0.305  -0.297
275   E        -1.694  -1.634  -1.515  -1.792  -1.705  -1.493  -1.520  -1.456  -1.271
276   F         0.049   0.085   0.034  -0.019   0.041  -0.094  -0.158  -0.101  -0.227
277   S        -0.254  -0.204  -0.575  -0.067  -0.001  -0.503  -0.263  -0.197  -0.706
278   T         1.032   1.041   1.096   1.040   1.053   1.139   1.099   1.110   1.190
279   G         1.032   1.041   1.096   1.058   1.071   1.156   1.099   1.110   1.190
280   P         0.049   0.167   0.050   0.126   0.307   0.089  -0.158   0.037  -0.196
281   H        -0.542  -0.607  -0.631  -0.367  -0.456  -0.524  -0.682  -0.755  -0.785
282   A        -1.088  -1.173  -1.127  -0.970  -1.095  -1.039  -1.101  -1.181  -1.089
283   P        -1.580  -1.559  -1.497  -1.338  -1.305  -1.252  -1.415  -1.382  -1.255
284   Y         1.032   1.041   1.096   1.087   1.099   1.182   1.099   1.110   1.190
285   T         1.032   1.041   1.096   1.040   1.053   1.139   1.099   1.110   1.190
286   H         1.032   1.041   1.096   1.181   1.190   1.267   1.099   1.110   1.190
287   W         1.032   1.041   1.096   1.260   1.268   1.339   1.099   1.110   1.190
288   K         1.032   1.041   1.096   0.932   0.948   1.041   1.099   1.110   1.190
289   Q         1.032   1.041   1.096   1.193   1.204   1.278   1.099   1.110   1.190
290   T         1.032   1.041   1.096   1.040   1.053   1.139   1.099   1.110   1.190
291   I         0.373   0.457   0.111   0.403   0.507   0.009   0.365   0.485  -0.087
292   F         1.032   1.041   1.096   1.074   1.087   1.170   1.099   1.110   1.190
293   Y         1.032   1.041   1.096   1.087   1.099   1.182   1.099   1.110   1.190
294   F        -1.694  -1.711  -1.516  -1.704  -1.725  -1.453  -1.520  -1.514  -1.271
295   P        -1.580  -1.560  -1.502  -1.578  -1.551  -1.443  -1.415  -1.383  -1.260
296   D        -1.088  -1.172  -1.124  -1.147  -1.269  -1.184  -1.101  -1.179  -1.086
297   D        -0.671  -0.688  -0.654  -0.914  -0.927  -0.808  -0.892  -0.902  -0.819
298   L         0.373   0.334   0.099   0.330   0.284  -0.070   0.365   0.304  -0.108
299   D        -1.694  -1.653  -1.513  -1.793  -1.708  -1.492  -1.520  -1.468  -1.269
300   A        -1.277  -1.196  -1.144  -1.362  -1.284  -1.140  -1.311  -1.229  -1.107
301   E        -1.163  -1.182  -1.128  -1.245  -1.247  -1.108  -1.206  -1.205  -1.091
302   T        -1.277  -1.233  -1.130  -1.355  -1.265  -1.101  -1.311  -1.247  -1.091
303   G         0.049   0.167   0.050   0.034   0.216   0.017  -0.158   0.037  -0.196
304   D         0.049  -0.030  -0.004  -0.158  -0.299  -0.263  -0.158  -0.305  -0.297
305   T        -2.300  -2.267  -2.066  -2.168  -2.123  -1.848  -1.730  -1.694  -1.451
306   I        -0.786  -0.733  -0.663  -1.064  -0.974  -0.881  -0.996  -0.928  -0.826
307   E        -1.883  -1.948  -1.816  -1.662  -1.744  -1.559  -1.520  -1.566  -1.377
308   G         0.373   0.332   0.098   0.508   0.461   0.145   0.365   0.301  -0.111
309   E        -0.671  -0.740  -0.655  -0.824  -0.909  -0.766  -0.892  -0.960  -0.820
310   L        -0.180  -0.152  -0.032  -0.577  -0.520  -0.318  -0.577  -0.531  -0.350
311   V        -1.580  -1.566  -1.486  -1.553  -1.517  -1.402  -1.415  -1.384  -1.245
312   C        -0.845  -0.839  -1.080  -0.436  -0.433  -0.844  -0.787  -0.779  -1.037
313   S        -1.883  -1.764  -1.789  -1.664  -1.502  -1.613  -1.520  -1.413  -1.357
314   P         1.032   1.041   1.096   1.172   1.180   1.259   1.099   1.110   1.190
315   N        -0.254  -0.330  -0.578  -0.015  -0.117  -0.518  -0.263  -0.372  -0.710
316   E        -1.163  -1.149  -1.116  -1.279  -1.231  -1.143  -1.206  -1.177  -1.080
317   K        -1.391  -1.313  -1.457  -1.330  -1.227  -1.440  -1.206  -1.129  -1.219
318   N         1.032   1.041   1.096   1.134   1.152   1.224   1.099   1.110   1.190
319   N        -1.088  -1.173  -1.127  -0.922  -1.034  -0.999  -1.101  -1.181  -1.089
320   R         1.032   1.041   1.096   1.177   1.183   1.263   1.099   1.110   1.190
321   D        -0.125  -0.130  -0.030  -0.467  -0.483  -0.308  -0.473  -0.490  -0.346
322   L         1.032   1.041   1.096   0.919   0.935   1.030   1.099   1.110   1.190
323   N         0.373   0.457   0.111   0.334   0.434  -0.013   0.365   0.485  -0.087
324   I         0.049   0.119   0.015  -0.090   0.022  -0.177  -0.158  -0.043  -0.261
325   K        -1.277  -1.271  -1.150  -1.540  -1.537  -1.323  -1.311  -1.302  -1.113
326   I        -0.254  -0.334  -0.583  -0.207  -0.319  -0.734  -0.263  -0.372  -0.718
327   S        -0.845  -0.838  -1.074  -0.716  -0.715  -1.123  -0.787  -0.783  -1.030
328   Y        -0.125  -0.111  -0.024  -0.172  -0.153  -0.018  -0.473  -0.455  -0.333
329   K        -1.277  -1.315  -1.146  -1.370  -1.423  -1.185  -1.311  -1.333  -1.109
330   F        -0.542  -0.548  -0.626  -0.500  -0.495  -0.605  -0.682  -0.681  -0.777
331   E        -0.542  -0.618  -0.638  -0.652  -0.744  -0.777  -0.682  -0.772  -0.797
332   S        -1.694  -1.651  -1.509  -1.589  -1.523  -1.308  -1.520  -1.473  -1.266
333   N        -2.300  -2.223  -2.062  -2.020  -1.903  -1.723  -1.730  -1.665  -1.448
334   G        -1.883  -1.948  -1.816  -1.712  -1.832  -1.657  -1.520  -1.566  -1.377
335   I        -0.854  -0.778  -0.670  -0.944  -0.802  -0.668  -1.090  -0.987  -0.835
336   D         0.244   0.068   0.033   0.174  -0.083  -0.135   0.167  -0.130  -0.227
337   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   N        -0.629  -0.542  -0.658  -0.765  -0.631  -0.810  -0.778  -0.658  -0.820
339   S        -0.985  -1.056  -1.117  -0.852  -0.961  -1.072  -0.954  -1.045  -1.077
340   R         0.315   0.190   0.069   0.516   0.331   0.101   0.278   0.076  -0.163
341   S        -1.677  -1.675  -1.522  -1.611  -1.582  -1.354  -1.501  -1.487  -1.276
342   R        -1.580  -1.596  -1.490  -1.587  -1.618  -1.459  -1.415  -1.413  -1.250
343   K        -1.391  -1.511  -1.490  -1.326  -1.506  -1.481  -1.206  -1.324  -1.249
344   N        -0.542  -0.550  -0.614  -0.510  -0.504  -0.628  -0.682  -0.672  -0.761
345   E        -1.997  -1.970  -1.813  -2.007  -1.982  -1.720  -1.625  -1.591  -1.375
346   G        -2.300  -2.246  -2.075  -1.964  -1.908  -1.658  -1.730  -1.681  -1.456
347   S        -1.580  -1.610  -1.497  -1.536  -1.583  -1.414  -1.415  -1.432  -1.256
348   Y         0.373   0.469   0.112   0.510   0.626   0.125   0.365   0.501  -0.086
349   L        -1.997  -1.999  -1.820  -1.912  -1.879  -1.627  -1.625  -1.610  -1.380
350   M         0.373   0.410   0.107   0.584   0.630   0.145   0.365   0.418  -0.093
351   H        -1.277  -1.289  -1.153  -1.117  -1.135  -0.962  -1.311  -1.313  -1.116
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P38074
Output conservation file - output/P38074
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
