1     M         1.182   1.184   1.196   1.383   1.384   1.402   1.228   1.230   1.244
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     T        -0.232  -0.253  -0.291  -0.193  -0.234  -0.312  -0.356  -0.388  -0.445
5     S         1.182   1.184   1.196   0.882   0.885   0.907   1.228   1.230   1.244
6     L         1.182   1.184   1.196   1.055   1.059   1.077   1.228   1.230   1.244
7     D         1.182   1.184   1.196   1.025   1.029   1.048   1.228   1.230   1.244
8     D         1.182   1.184   1.196   1.025   1.029   1.048   1.228   1.230   1.244
9     T         1.182   1.184   1.196   1.285   1.287   1.305   1.228   1.230   1.244
10    I         1.182   1.184   1.196   1.207   1.208   1.228   1.228   1.230   1.244
11    I         1.182   1.184   1.196   1.207   1.208   1.228   1.228   1.230   1.244
12    S        -0.232  -0.253  -0.291  -0.513  -0.544  -0.591  -0.356  -0.388  -0.445
13    Y        -0.232  -0.234  -0.289  -0.100  -0.100  -0.193  -0.356  -0.358  -0.442
14    Q        -0.232  -0.253  -0.291  -0.049  -0.087  -0.167  -0.356  -0.388  -0.445
15    N         1.182   1.184   1.196   1.091   1.091   1.114   1.228   1.230   1.244
16    I        -0.232  -0.234  -0.289  -0.353  -0.355  -0.440  -0.356  -0.358  -0.442
17    M        -0.232  -0.253  -0.291  -0.119  -0.160  -0.248  -0.356  -0.388  -0.445
18    L         1.182   1.184   1.196   1.055   1.059   1.077   1.228   1.230   1.244
19    L         1.182   1.184   1.196   1.055   1.059   1.077   1.228   1.230   1.244
20    D         1.182   1.184   1.196   1.025   1.029   1.048   1.228   1.230   1.244
21    N         1.182   1.184   1.196   1.091   1.091   1.114   1.228   1.230   1.244
22    M        -0.232  -0.234  -0.289   0.007   0.004  -0.084  -0.356  -0.358  -0.442
23    T         1.182   1.184   1.196   1.285   1.287   1.305   1.228   1.230   1.244
24    N         1.182   1.184   1.196   1.091   1.091   1.114   1.228   1.230   1.244
25    Y        -0.232  -0.253  -0.291  -0.196  -0.234  -0.320  -0.356  -0.388  -0.445
26    N         1.182   1.184   1.196   1.091   1.091   1.114   1.228   1.230   1.244
27    K         1.182   1.184   1.196   1.171   1.176   1.193   1.228   1.230   1.244
28    P         1.182   1.184   1.196   1.369   1.371   1.388   1.228   1.230   1.244
29    A         1.182   1.184   1.196   1.376   1.378   1.395   1.228   1.230   1.244
30    I        -0.232  -0.200  -0.276  -0.282  -0.227  -0.370  -0.356  -0.307  -0.422
31    D         1.182   1.184   1.196   1.025   1.029   1.048   1.228   1.230   1.244
32    Y         1.182   1.184   1.196   1.299   1.303   1.319   1.228   1.230   1.244
33    F         1.182   1.184   1.196   1.389   1.392   1.409   1.228   1.230   1.244
34    H         1.182   1.184   1.196   1.278   1.280   1.298   1.228   1.230   1.244
35    H        -0.232  -0.200  -0.276  -0.058  -0.013  -0.122  -0.356  -0.307  -0.422
36    E        -1.258  -1.255  -1.231  -1.371  -1.364  -1.325  -1.148  -1.142  -1.102
37    F         1.182   1.184   1.196   1.389   1.392   1.409   1.228   1.230   1.244
38    N        -1.258  -1.255  -1.231  -1.238  -1.221  -1.192  -1.148  -1.142  -1.102
39    D        -0.358  -0.356  -0.335  -0.474  -0.471  -0.436  -0.554  -0.550  -0.515
40    A        -1.258  -1.255  -1.231  -1.274  -1.257  -1.228  -1.148  -1.142  -1.102
41    S        -0.232  -0.234  -0.289  -0.285  -0.290  -0.422  -0.356  -0.358  -0.442
42    L        -1.258  -1.255  -1.231  -1.106  -1.102  -1.062  -1.148  -1.142  -1.102
43    E        -1.258  -1.255  -1.231  -1.189  -1.171  -1.144  -1.148  -1.142  -1.102
44    I         1.182   1.184   1.196   1.207   1.208   1.228   1.228   1.230   1.244
45    S        -0.232  -0.253  -0.291  -0.384  -0.408  -0.433  -0.356  -0.388  -0.445
46    A        -1.258  -1.255  -1.231  -1.171  -1.159  -1.126  -1.148  -1.142  -1.102
47    S        -0.232  -0.253  -0.291  -0.474  -0.503  -0.543  -0.356  -0.388  -0.445
48    W         1.182   1.184   1.196   1.444   1.447   1.463   1.228   1.230   1.244
49    T        -1.258  -1.255  -1.231  -1.352  -1.334  -1.306  -1.148  -1.142  -1.102
50    L        -0.232  -0.253  -0.291  -0.279  -0.306  -0.352  -0.356  -0.388  -0.445
51    L         1.182   1.184   1.196   1.055   1.059   1.077   1.228   1.230   1.244
52    L         1.182   1.184   1.196   1.055   1.059   1.077   1.228   1.230   1.244
53    K         1.182   1.184   1.196   1.171   1.176   1.193   1.228   1.230   1.244
54    M        -0.232  -0.253  -0.291   0.016  -0.018  -0.081  -0.356  -0.388  -0.445
55    R        -0.232  -0.253  -0.291  -0.027  -0.055  -0.107  -0.356  -0.388  -0.445
56    K         1.182   1.184   1.196   1.171   1.176   1.193   1.228   1.230   1.244
57    H         1.182   1.184   1.196   1.278   1.280   1.298   1.228   1.230   1.244
58    K         1.182   1.184   1.196   1.171   1.176   1.193   1.228   1.230   1.244
59    L        -0.232  -0.234  -0.289  -0.138  -0.142  -0.262  -0.356  -0.358  -0.442
60    L         1.182   1.184   1.196   1.055   1.059   1.077   1.228   1.230   1.244
61    R         1.182   1.184   1.196   1.285   1.289   1.305   1.228   1.230   1.244
62    L         1.182   1.184   1.196   1.055   1.059   1.077   1.228   1.230   1.244
63    P         1.182   1.184   1.196   1.369   1.371   1.388   1.228   1.230   1.244
64    S         1.182   1.184   1.196   0.882   0.885   0.907   1.228   1.230   1.244
65    C         1.182   1.184   1.196   1.465   1.466   1.484   1.228   1.230   1.244
66    S         1.182   1.184   1.196   0.882   0.885   0.907   1.228   1.230   1.244
67    S        -1.258  -1.255  -1.231  -1.324  -1.312  -1.278  -1.148  -1.142  -1.102
68    E         1.182   1.184   1.196   1.200   1.201   1.221   1.228   1.230   1.244
69    D         1.182   1.184   1.196   1.025   1.029   1.048   1.228   1.230   1.244
70    V        -1.258  -1.255  -1.231  -1.197  -1.185  -1.152  -1.148  -1.142  -1.102
71    L        -0.232  -0.253  -0.291  -0.506  -0.546  -0.633  -0.356  -0.388  -0.445
72    D         1.182   1.184   1.196   1.025   1.029   1.048   1.228   1.230   1.244
73    Y         1.182   1.184   1.196   1.299   1.303   1.319   1.228   1.230   1.244
74    N         1.182   1.184   1.196   1.091   1.091   1.114   1.228   1.230   1.244
75    M        -1.258  -1.255  -1.231  -1.017  -1.008  -0.974  -1.148  -1.142  -1.102
76    Y         1.182   1.184   1.196   1.299   1.303   1.319   1.228   1.230   1.244
77    L         1.182   1.184   1.196   1.055   1.059   1.077   1.228   1.230   1.244
78    V        -1.258  -1.255  -1.231  -1.110  -1.103  -1.066  -1.148  -1.142  -1.102
79    R         1.182   1.184   1.196   1.285   1.289   1.305   1.228   1.230   1.244
80    L         1.182   1.184   1.196   1.055   1.059   1.077   1.228   1.230   1.244
81    H         1.182   1.184   1.196   1.278   1.280   1.298   1.228   1.230   1.244
82    H         1.182   1.184   1.196   1.278   1.280   1.298   1.228   1.230   1.244
83    C         1.182   1.184   1.196   1.465   1.466   1.484   1.228   1.230   1.244
84    L         1.182   1.184   1.196   1.055   1.059   1.077   1.228   1.230   1.244
85    W         1.182   1.184   1.196   1.444   1.447   1.463   1.228   1.230   1.244
86    R         1.182   1.184   1.196   1.285   1.289   1.305   1.228   1.230   1.244
87    R         1.182   1.184   1.196   1.285   1.289   1.305   1.228   1.230   1.244
88    W         1.182   1.184   1.196   1.444   1.447   1.463   1.228   1.230   1.244
89    S         1.182   1.184   1.196   0.882   0.885   0.907   1.228   1.230   1.244
90    I        -0.232  -0.234  -0.289  -0.052  -0.057  -0.162  -0.356  -0.358  -0.442
91    N        -1.258  -1.255  -1.231  -1.278  -1.272  -1.233  -1.148  -1.142  -1.102
92    H        -1.258  -1.255  -1.231  -1.301  -1.294  -1.255  -1.148  -1.142  -1.102
93    Y        -0.232  -0.234  -0.289  -0.005  -0.008  -0.106  -0.356  -0.358  -0.442
94    G        -1.258  -1.255  -1.231  -0.931  -0.917  -0.888  -1.148  -1.142  -1.102
95    L         1.182   1.184   1.196   1.055   1.059   1.077   1.228   1.230   1.244
96    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
97    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
98    Q        -1.258  -1.255  -1.231  -1.132  -1.130  -1.087  -1.148  -1.142  -1.102
99    N        -1.258  -1.255  -1.231  -1.371  -1.361  -1.325  -1.148  -1.142  -1.102
100   S        -1.258  -1.255  -1.231  -1.458  -1.459  -1.410  -1.148  -1.142  -1.102
101   K        -0.232  -0.200  -0.276  -0.209  -0.158  -0.276  -0.356  -0.307  -0.422
102   S        -1.258  -1.255  -1.231  -1.419  -1.404  -1.372  -1.148  -1.142  -1.102
103   N        -0.232  -0.234  -0.289  -0.435  -0.439  -0.534  -0.356  -0.358  -0.442
104   P         1.182   1.184   1.196   1.369   1.371   1.388   1.228   1.230   1.244
105   L         1.182   1.184   1.196   1.055   1.059   1.077   1.228   1.230   1.244
106   S        -1.258  -1.255  -1.231  -1.220  -1.217  -1.175  -1.148  -1.142  -1.102
107   I         1.182   1.184   1.196   1.207   1.208   1.228   1.228   1.230   1.244
108   N         1.182   1.184   1.196   1.091   1.091   1.114   1.228   1.230   1.244
109   W         1.182   1.184   1.196   1.444   1.447   1.463   1.228   1.230   1.244
110   N         1.182   1.184   1.196   1.091   1.091   1.114   1.228   1.230   1.244
111   K         1.182   1.184   1.196   1.171   1.176   1.193   1.228   1.230   1.244
112   E        -0.232  -0.200  -0.276  -0.302  -0.246  -0.392  -0.356  -0.307  -0.422
113   T        -0.232  -0.253  -0.291  -0.193  -0.234  -0.312  -0.356  -0.388  -0.445
114   D         1.182   1.184   1.196   1.025   1.029   1.048   1.228   1.230   1.244
115   V        -0.232  -0.253  -0.291   0.007  -0.026  -0.086  -0.356  -0.388  -0.445
116   T         1.182   1.184   1.196   1.285   1.287   1.305   1.228   1.230   1.244
117   V         1.182   1.184   1.196   1.362   1.364   1.382   1.228   1.230   1.244
118   L         1.182   1.184   1.196   1.055   1.059   1.077   1.228   1.230   1.244
119   Y         1.182   1.184   1.196   1.299   1.303   1.319   1.228   1.230   1.244
120   G         1.182   1.184   1.196   1.458   1.459   1.477   1.228   1.230   1.244
121   P         1.182   1.184   1.196   1.369   1.371   1.388   1.228   1.230   1.244
122   D        -0.232  -0.253  -0.291  -0.285  -0.312  -0.352  -0.356  -0.388  -0.445
123   L         1.182   1.184   1.196   1.055   1.059   1.077   1.228   1.230   1.244
124   T        -0.232  -0.234  -0.289  -0.474  -0.476  -0.541  -0.356  -0.358  -0.442
125   N        -1.258  -1.255  -1.231  -1.265  -1.271  -1.219  -1.148  -1.142  -1.102
126   I        -1.258  -1.255  -1.231  -1.189  -1.193  -1.144  -1.148  -1.142  -1.102
127   D        -1.258  -1.255  -1.231  -1.132  -1.119  -1.087  -1.148  -1.142  -1.102
128   S        -1.258  -1.255  -1.231  -1.171  -1.168  -1.126  -1.148  -1.142  -1.102
129   N        -0.232  -0.253  -0.291  -0.239  -0.271  -0.314  -0.356  -0.388  -0.445
130   E        -0.358  -0.356  -0.335  -0.326  -0.323  -0.290  -0.554  -0.550  -0.515
131   N        -0.232  -0.253  -0.291  -0.282  -0.316  -0.366  -0.356  -0.388  -0.445
132   E        -1.258  -1.255  -1.231  -1.017  -1.008  -0.974  -1.148  -1.142  -1.102
133   I        -1.258  -1.255  -1.231  -1.224  -1.225  -1.179  -1.148  -1.142  -1.102
134   S        -1.258  -1.255  -1.231  -1.386  -1.382  -1.339  -1.148  -1.142  -1.102
135   P         1.182   1.184   1.196   1.369   1.371   1.388   1.228   1.230   1.244
136   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
137   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
138   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
139   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
140   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
141   D        -0.232  -0.234  -0.289  -0.329  -0.330  -0.444  -0.356  -0.358  -0.442
142   Q        -0.232  -0.234  -0.289  -0.154  -0.154  -0.229  -0.356  -0.358  -0.442
143   K         1.182   1.184   1.196   1.171   1.176   1.193   1.228   1.230   1.244
144   Q        -0.232  -0.234  -0.289  -0.415  -0.417  -0.469  -0.356  -0.358  -0.442
145   T        -1.258  -1.255  -1.231  -1.352  -1.353  -1.306  -1.148  -1.142  -1.102
146   K        -0.232  -0.234  -0.289  -0.080  -0.083  -0.193  -0.356  -0.358  -0.442
147   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
148   N        -1.258  -1.255  -1.231  -1.405  -1.414  -1.358  -1.148  -1.142  -1.102
149   L        -0.232  -0.253  -0.291  -0.269  -0.296  -0.340  -0.356  -0.388  -0.445
150   K        -0.232  -0.253  -0.291  -0.160  -0.188  -0.240  -0.356  -0.388  -0.445
151   S         1.182   1.184   1.196   0.882   0.885   0.907   1.228   1.230   1.244
152   A        -0.232  -0.200  -0.276   0.056   0.102  -0.008  -0.356  -0.307  -0.422
153   L        -0.232  -0.253  -0.291  -0.269  -0.296  -0.340  -0.356  -0.388  -0.445
154   K        -1.258  -1.255  -1.231  -1.206  -1.209  -1.161  -1.148  -1.142  -1.102
155   K        -1.258  -1.255  -1.231  -1.050  -1.041  -1.007  -1.148  -1.142  -1.102
156   N        -1.258  -1.255  -1.231  -1.583  -1.572  -1.535  -1.148  -1.142  -1.102
157   T        -1.258  -1.255  -1.231  -1.220  -1.228  -1.175  -1.148  -1.142  -1.102
158   E        -0.232  -0.234  -0.289  -0.384  -0.386  -0.470  -0.356  -0.358  -0.442
159   C        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
160   W        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
161   V        -1.258  -1.255  -1.231  -1.288  -1.277  -1.242  -1.148  -1.142  -1.102
162   T        -1.258  -1.255  -1.231  -1.247  -1.234  -1.201  -1.148  -1.142  -1.102
163   E        -0.232  -0.253  -0.291  -0.366  -0.411  -0.502  -0.356  -0.388  -0.445
164   E        -0.232  -0.253  -0.291  -0.177  -0.209  -0.267  -0.356  -0.388  -0.445
165   V        -1.258  -1.255  -1.231  -1.171  -1.179  -1.126  -1.148  -1.142  -1.102
166   D        -1.258  -1.255  -1.231  -1.171  -1.160  -1.126  -1.148  -1.142  -1.102
167   E        -1.258  -1.255  -1.231  -1.324  -1.331  -1.278  -1.148  -1.142  -1.102
168   I        -0.232  -0.234  -0.289  -0.128  -0.131  -0.232  -0.356  -0.358  -0.442
169   N         1.182   1.184   1.196   1.091   1.091   1.114   1.228   1.230   1.244
170   A        -1.258  -1.255  -1.231  -1.256  -1.247  -1.210  -1.148  -1.142  -1.102
171   S        -1.258  -1.255  -1.231  -1.202  -1.200  -1.157  -1.148  -1.142  -1.102
172   I        -0.232  -0.234  -0.289  -0.513  -0.516  -0.589  -0.356  -0.358  -0.442
173   E        -0.232  -0.234  -0.289  -0.516  -0.520  -0.593  -0.356  -0.358  -0.442
174   S        -0.358  -0.356  -0.335  -0.692  -0.689  -0.652  -0.554  -0.550  -0.515
175   N        -0.358  -0.356  -0.335  -0.423  -0.420  -0.386  -0.554  -0.550  -0.515
176   D         1.182   1.184   1.196   1.051   1.054   1.074   1.228   1.230   1.244
177   N        -0.358  -0.356  -0.335  -0.423  -0.420  -0.386  -0.554  -0.550  -0.515
178   A        -0.358  -0.356  -0.335  -0.503  -0.500  -0.465  -0.554  -0.550  -0.515
179   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
180   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
181   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
182   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
183   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
184   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
185   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
186   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
187   C        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
188   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
189   S         1.182   1.184   1.196   0.882   0.885   0.907   1.228   1.230   1.244
190   S        -0.232  -0.253  -0.291  -0.432  -0.458  -0.492  -0.356  -0.388  -0.445
191   V        -0.232  -0.253  -0.291  -0.036  -0.072  -0.140  -0.356  -0.388  -0.445
192   D        -0.232  -0.234  -0.289  -0.404  -0.410  -0.514  -0.356  -0.358  -0.442
193   S         1.182   1.184   1.196   0.882   0.885   0.907   1.228   1.230   1.244
194   H        -1.258  -1.255  -1.231  -1.453  -1.440  -1.406  -1.148  -1.142  -1.102
195   T        -0.232  -0.253  -0.291  -0.065  -0.096  -0.153  -0.356  -0.388  -0.445
196   S         1.182   1.184   1.196   0.882   0.885   0.907   1.228   1.230   1.244
197   S         1.182   1.184   1.196   0.882   0.885   0.907   1.228   1.230   1.244
198   I         1.182   1.184   1.196   1.207   1.208   1.228   1.228   1.230   1.244
199   F         1.182   1.184   1.196   1.389   1.392   1.409   1.228   1.230   1.244
200   D        -0.232  -0.234  -0.289  -0.302  -0.306  -0.419  -0.356  -0.358  -0.442
201   Q        -1.258  -1.255  -1.231  -1.149  -1.145  -1.105  -1.148  -1.142  -1.102
202   H        -1.258  -1.255  -1.231  -1.283  -1.289  -1.237  -1.148  -1.142  -1.102
203   S        -0.358  -0.356  -0.335  -0.650  -0.647  -0.610  -0.554  -0.550  -0.515
204   T        -0.358  -0.356  -0.335  -0.258  -0.255  -0.222  -0.554  -0.550  -0.515
205   C        -0.358  -0.356  -0.335  -0.285  -0.282  -0.249  -0.554  -0.550  -0.515
206   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
207   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
208   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
209   T         1.182   1.184   1.196   1.274   1.276   1.294   1.228   1.230   1.244
210   K        -0.358  -0.356  -0.335  -0.553  -0.550  -0.515  -0.554  -0.550  -0.515
211   I        -0.358  -0.356  -0.335  -0.680  -0.677  -0.640  -0.554  -0.550  -0.515
212   S         1.182   1.184   1.196   0.907   0.909   0.931   1.228   1.230   1.244
213   S        -0.358  -0.356  -0.335  -0.473  -0.470  -0.436  -0.554  -0.550  -0.515
214   I        -1.258  -1.255  -1.231  -1.013  -1.004  -0.970  -1.148  -1.142  -1.102
215   D        -1.258  -1.255  -1.231  -1.329  -1.305  -1.283  -1.148  -1.142  -1.102
216   E        -1.258  -1.255  -1.231  -1.409  -1.411  -1.362  -1.148  -1.142  -1.102
217   D        -0.232  -0.253  -0.291  -0.302  -0.329  -0.373  -0.356  -0.388  -0.445
218   S        -1.258  -1.255  -1.231  -1.278  -1.269  -1.233  -1.148  -1.142  -1.102
219   E        -1.258  -1.255  -1.231  -1.507  -1.504  -1.459  -1.148  -1.142  -1.102
220   D        -1.258  -1.255  -1.231  -1.251  -1.243  -1.206  -1.148  -1.142  -1.102
221   L        -0.232  -0.253  -0.291  -0.319  -0.349  -0.401  -0.356  -0.388  -0.445
222   M        -1.258  -1.255  -1.231  -1.162  -1.170  -1.118  -1.148  -1.142  -1.102
223   N        -0.232  -0.200  -0.276  -0.226  -0.185  -0.279  -0.356  -0.307  -0.422
224   E        -1.258  -1.255  -1.231  -1.278  -1.275  -1.233  -1.148  -1.142  -1.102
225   K         1.182   1.184   1.196   1.171   1.176   1.193   1.228   1.230   1.244
226   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
228   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
229   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
230   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
231   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
232   K        -1.258  -1.255  -1.231  -1.482  -1.468  -1.435  -1.148  -1.142  -1.102
233   L        -0.232  -0.253  -0.291  -0.353  -0.385  -0.443  -0.356  -0.388  -0.445
234   K        -0.232  -0.234  -0.289  -0.157  -0.158  -0.264  -0.356  -0.358  -0.442
235   F         1.182   1.184   1.196   1.389   1.392   1.409   1.228   1.230   1.244
236   N        -0.232  -0.234  -0.289  -0.435  -0.439  -0.534  -0.356  -0.358  -0.442
237   Q        -0.232  -0.234  -0.289  -0.285  -0.287  -0.350  -0.356  -0.358  -0.442
238   A        -0.232  -0.253  -0.291  -0.199  -0.245  -0.346  -0.356  -0.388  -0.445
239   V         1.182   1.184   1.196   1.362   1.364   1.382   1.228   1.230   1.244
240   M        -1.258  -1.255  -1.231  -0.919  -0.915  -0.876  -1.148  -1.142  -1.102
241   K        -0.232  -0.253  -0.291  -0.209  -0.239  -0.299  -0.356  -0.388  -0.445
242   R         1.182   1.184   1.196   1.285   1.289   1.305   1.228   1.230   1.244
243   E        -0.232  -0.200  -0.276  -0.148  -0.102  -0.210  -0.356  -0.307  -0.422
244   I         1.182   1.184   1.196   1.207   1.208   1.228   1.228   1.230   1.244
245   D         1.182   1.184   1.196   1.025   1.029   1.048   1.228   1.230   1.244
246   S        -0.232  -0.234  -0.289  -0.292  -0.297  -0.429  -0.356  -0.358  -0.442
247   K        -0.232  -0.234  -0.289  -0.531  -0.532  -0.610  -0.356  -0.358  -0.442
248   G         1.182   1.184   1.196   1.458   1.459   1.477   1.228   1.230   1.244
249   T        -1.258  -1.255  -1.231  -1.106  -1.093  -1.062  -1.148  -1.142  -1.102
250   I        -0.232  -0.200  -0.276  -0.170  -0.122  -0.238  -0.356  -0.307  -0.422
251   R        -1.258  -1.255  -1.231  -1.034  -1.025  -0.990  -1.148  -1.142  -1.102
252   E        -0.232  -0.253  -0.291  -0.302  -0.342  -0.422  -0.356  -0.388  -0.445
253   S        -1.258  -1.255  -1.231  -1.215  -1.204  -1.170  -1.148  -1.142  -1.102
254   L        -1.258  -1.255  -1.231  -1.166  -1.160  -1.122  -1.148  -1.142  -1.102
255   I        -1.258  -1.255  -1.231  -1.329  -1.336  -1.283  -1.148  -1.142  -1.102
256   N        -1.258  -1.255  -1.231  -1.145  -1.136  -1.100  -1.148  -1.142  -1.102
257   I         1.182   1.184   1.196   1.207   1.208   1.228   1.228   1.230   1.244
258   N         1.182   1.184   1.196   1.091   1.091   1.114   1.228   1.230   1.244
259   D         1.182   1.184   1.196   1.025   1.029   1.048   1.228   1.230   1.244
260   I        -0.358  -0.356  -0.335  -0.410  -0.406  -0.372  -0.554  -0.550  -0.515
261   Q        -0.358  -0.356  -0.335  -0.151  -0.148  -0.117  -0.554  -0.550  -0.515
262   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
263   S        -1.258  -1.255  -1.231  -1.292  -1.279  -1.246  -1.148  -1.142  -1.102
264   R        -0.232  -0.253  -0.291  -0.193  -0.232  -0.312  -0.356  -0.388  -0.445
265   H        -0.232  -0.234  -0.289  -0.186  -0.190  -0.277  -0.356  -0.358  -0.442
266   H        -1.258  -1.255  -1.231  -0.915  -0.911  -0.872  -1.148  -1.142  -1.102
267   R        -1.258  -1.255  -1.231  -0.988  -0.989  -0.945  -1.148  -1.142  -1.102
268   R        -0.232  -0.253  -0.291  -0.062  -0.092  -0.150  -0.356  -0.388  -0.445
269   H        -0.232  -0.234  -0.289  -0.109  -0.111  -0.205  -0.356  -0.358  -0.442
270   H        -1.258  -1.255  -1.231  -1.021  -1.010  -0.978  -1.148  -1.142  -1.102
271   R        -1.258  -1.255  -1.231  -1.119  -1.122  -1.075  -1.148  -1.142  -1.102
272   R        -1.258  -1.255  -1.231  -0.996  -0.979  -0.953  -1.148  -1.142  -1.102
273   H        -1.258  -1.255  -1.231  -0.980  -0.970  -0.937  -1.148  -1.142  -1.102
274   H        -1.258  -1.255  -1.231  -1.029  -1.030  -0.986  -1.148  -1.142  -1.102
275   H        -1.258  -1.255  -1.231  -1.171  -1.170  -1.126  -1.148  -1.142  -1.102
276   H        -1.258  -1.255  -1.231  -1.453  -1.440  -1.406  -1.148  -1.142  -1.102
277   H        -1.258  -1.255  -1.231  -0.996  -0.988  -0.953  -1.148  -1.142  -1.102
278   H         1.182   1.184   1.196   1.278   1.280   1.298   1.228   1.230   1.244
279   Q        -1.258  -1.255  -1.231  -1.189  -1.184  -1.144  -1.148  -1.142  -1.102
280   N        -0.232  -0.253  -0.291  -0.470  -0.516  -0.600  -0.356  -0.388  -0.445
281   S        -0.232  -0.253  -0.291  -0.603  -0.639  -0.702  -0.356  -0.388  -0.445
282   S        -1.258  -1.255  -1.231  -1.338  -1.337  -1.292  -1.148  -1.142  -1.102
283   H        -1.258  -1.255  -1.231  -1.338  -1.322  -1.292  -1.148  -1.142  -1.102
284   S        -1.258  -1.255  -1.231  -1.458  -1.459  -1.410  -1.148  -1.142  -1.102
285   D         1.182   1.184   1.196   1.025   1.029   1.048   1.228   1.230   1.244
286   E        -0.232  -0.200  -0.276  -0.135  -0.090  -0.195  -0.356  -0.307  -0.422
287   T        -1.258  -1.255  -1.231  -1.084  -1.091  -1.041  -1.148  -1.142  -1.102
288   I        -0.358  -0.356  -0.335  -0.503  -0.500  -0.465  -0.554  -0.550  -0.515
289   K        -0.358  -0.356  -0.335  -0.345  -0.342  -0.308  -0.554  -0.550  -0.515
290   E        -0.358  -0.356  -0.335  -0.324  -0.321  -0.287  -0.554  -0.550  -0.515
291   A        -0.358  -0.356  -0.335  -0.180  -0.177  -0.145  -0.554  -0.550  -0.515
292   H        -0.358  -0.356  -0.335  -0.261  -0.258  -0.226  -0.554  -0.550  -0.515
293   Y         1.182   1.184   1.196   1.299   1.303   1.319   1.228   1.230   1.244
294   E         1.182   1.184   1.196   1.167   1.170   1.189   1.228   1.230   1.244
295   F        -0.358  -0.356  -0.335  -0.184  -0.181  -0.149  -0.554  -0.550  -0.515
296   S        -0.358  -0.356  -0.335  -0.680  -0.677  -0.640  -0.554  -0.550  -0.515
297   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
298   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
299   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
300   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
301   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
302   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
303   M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
304   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
305   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
306   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
307   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
308   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
309   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
310   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
311   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
312   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
313   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
314   V        -0.358  -0.356  -0.335  -0.338  -0.335  -0.301  -0.554  -0.550  -0.515
315   F        -1.258  -1.255  -1.231  -1.357  -1.342  -1.311  -1.148  -1.142  -1.102
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P36155
Output conservation file - output/P36155
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
