1     M         1.328   1.349   1.420   1.596   1.622   1.725   1.428   1.460   1.569
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     F         0.116   0.080   0.161  -0.083  -0.176  -0.078  -0.169  -0.245  -0.139
4     S        -1.203  -1.227  -1.097  -1.219  -1.255  -1.063  -1.167  -1.180  -1.002
5     R        -0.323  -0.417  -0.491   0.043  -0.125  -0.247  -0.368  -0.505  -0.600
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    L        -0.323  -0.413  -0.496  -0.330  -0.451  -0.555  -0.368  -0.500  -0.607
12    S        -0.597  -0.510  -0.530  -0.674  -0.544  -0.575  -0.768  -0.654  -0.658
13    R        -1.037  -1.060  -1.068  -0.737  -0.804  -0.863  -0.967  -0.997  -0.970
14    S        -0.763  -0.730  -0.588  -0.947  -0.892  -0.680  -0.967  -0.922  -0.729
15    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    S        -1.642  -1.629  -1.515  -1.589  -1.530  -1.340  -1.366  -1.347  -1.185
17    K        -1.642  -1.622  -1.509  -1.652  -1.626  -1.410  -1.366  -1.342  -1.180
18    A        -0.726  -0.714  -0.586  -0.990  -0.977  -0.760  -0.918  -0.902  -0.727
19    L        -0.726  -0.717  -0.587  -0.989  -0.985  -0.761  -0.918  -0.906  -0.728
20    P         1.328   1.349   1.420   1.343   1.369   1.486   1.428   1.460   1.569
21    I        -0.583  -0.565  -0.528  -0.612  -0.572  -0.479  -0.772  -0.739  -0.659
22    A         0.547   0.389   0.296   0.627   0.374   0.187   0.548   0.297   0.109
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
45    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
46    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
47    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
48    L        -0.491  -0.415  -0.510  -0.570  -0.457  -0.616  -0.625  -0.519  -0.630
49    G        -0.726  -0.717  -0.587  -0.943  -0.935  -0.728  -0.918  -0.906  -0.728
50    T        -1.103  -1.039  -1.042  -1.066  -0.971  -0.980  -1.065  -0.982  -0.948
51    V        -0.491  -0.369  -0.500  -0.573  -0.374  -0.624  -0.625  -0.457  -0.618
52    A        -1.103  -1.160  -1.076  -1.096  -1.196  -1.068  -1.065  -1.109  -0.980
53    I        -1.245  -1.273  -1.093  -1.328  -1.395  -1.111  -1.211  -1.221  -0.999
54    A        -0.597  -0.510  -0.522  -0.746  -0.601  -0.627  -0.768  -0.642  -0.644
55    A        -1.622  -1.616  -1.493  -1.619  -1.630  -1.452  -1.358  -1.343  -1.168
56    A         1.328   1.349   1.420   1.369   1.386   1.510   1.428   1.460   1.569
57    T        -1.622  -1.539  -1.490  -1.622  -1.509  -1.427  -1.358  -1.278  -1.166
58    A        -0.491  -0.428  -0.495  -0.430  -0.340  -0.439  -0.625  -0.526  -0.608
59    F        -0.868  -0.763  -1.008  -0.589  -0.436  -0.872  -0.772  -0.644  -0.906
60    Y        -1.103  -1.121  -1.063  -0.967  -0.986  -0.922  -1.065  -1.072  -0.967
61    F        -0.726  -0.643  -0.560  -0.955  -0.799  -0.707  -0.918  -0.806  -0.693
62    A        -1.037  -0.887  -1.032  -0.889  -0.672  -0.890  -0.967  -0.789  -0.932
63    N        -0.597  -0.557  -0.541  -0.613  -0.588  -0.522  -0.768  -0.727  -0.674
64    R        -1.310  -1.260  -1.117  -1.117  -1.080  -0.846  -1.266  -1.207  -1.020
65    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
66    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
67    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
68    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
69    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
70    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
71    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
72    S        -1.622  -1.640  -1.490  -1.384  -1.415  -1.176  -1.358  -1.361  -1.166
73    F        -1.479  -1.394  -1.445  -1.263  -1.140  -1.228  -1.211  -1.119  -1.125
74    V         0.189   0.135   0.171   0.132   0.028   0.058  -0.038  -0.144  -0.120
75    F        -1.622  -1.555  -1.486  -1.545  -1.498  -1.358  -1.358  -1.289  -1.163
76    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
77    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
78    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
79    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
80    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
81    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
82    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
83    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
84    N         0.547   0.389   0.296   0.698   0.472   0.292   0.548   0.297   0.109
85    E         0.189   0.221   0.197   0.155   0.202   0.123  -0.038   0.011  -0.072
86    S        -1.479  -1.531  -1.480  -1.288  -1.373  -1.313  -1.211  -1.258  -1.155
87    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
88    N        -1.999  -1.994  -1.850  -1.985  -2.023  -1.779  -1.505  -1.490  -1.302
89    K         0.547   0.546   0.324   0.398   0.404   0.093   0.548   0.545   0.158
90    V        -0.726  -0.715  -0.586  -0.869  -0.860  -0.663  -0.918  -0.904  -0.727
91    F         0.547   0.546   0.324   0.643   0.647   0.277   0.548   0.545   0.158
92    K        -1.622  -1.621  -1.501  -1.782  -1.770  -1.598  -1.358  -1.347  -1.174
93    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
94    G         0.547   0.628   0.332   0.567   0.671   0.255   0.548   0.668   0.173
95    D        -0.188  -0.040  -0.418  -0.027   0.171  -0.376  -0.185   0.013  -0.501
96    D        -1.103  -1.140  -1.059  -0.949  -0.985  -0.845  -1.065  -1.092  -0.965
97    K        -1.103  -1.177  -1.073  -1.169  -1.286  -1.125  -1.065  -1.129  -0.978
98    W         1.328   1.349   1.420   1.605   1.636   1.735   1.428   1.460   1.569
99    I        -0.491  -0.588  -0.525  -0.533  -0.691  -0.622  -0.625  -0.735  -0.651
100   D         0.547   0.389   0.296   0.647   0.429   0.264   0.548   0.297   0.109
101   L         1.328   1.349   1.420   1.193   1.221   1.344   1.428   1.460   1.569
102   P        -0.491  -0.415  -0.510  -0.746  -0.629  -0.741  -0.625  -0.519  -0.630
103   I         0.189   0.252   0.215  -0.034   0.064  -0.006  -0.038   0.065  -0.038
104   S        -1.622  -1.545  -1.483  -1.603  -1.492  -1.417  -1.358  -1.282  -1.160
105   K        -0.188  -0.343  -0.467  -0.281  -0.493  -0.672  -0.185  -0.399  -0.567
106   I        -0.583  -0.660  -0.548  -0.686  -0.779  -0.610  -0.772  -0.843  -0.682
107   E        -1.103  -1.020  -1.046  -1.041  -0.927  -0.962  -1.065  -0.967  -0.952
108   E        -1.103  -1.140  -1.077  -1.181  -1.256  -1.200  -1.065  -1.094  -0.982
109   E        -1.103  -1.119  -1.059  -1.191  -1.218  -1.105  -1.065  -1.076  -0.965
110   S        -0.491  -0.549  -0.514  -0.510  -0.566  -0.541  -0.625  -0.679  -0.634
111   H         1.328   1.349   1.420   1.556   1.585   1.688   1.428   1.460   1.569
112   D         0.028   0.071   0.163  -0.140  -0.063   0.065  -0.332  -0.262  -0.135
113   T         1.328   1.349   1.420   1.348   1.389   1.491   1.428   1.460   1.569
114   R         0.547   0.602   0.326   0.438   0.513   0.181   0.548   0.629   0.162
115   R        -0.491  -0.428  -0.495  -0.212  -0.119  -0.241  -0.625  -0.526  -0.608
116   F         0.028   0.033   0.152  -0.271  -0.286  -0.099  -0.332  -0.332  -0.157
117   T        -1.622  -1.646  -1.507  -1.454  -1.452  -1.268  -1.358  -1.365  -1.179
118   F         1.328   1.349   1.420   1.369   1.404   1.510   1.428   1.460   1.569
119   K        -1.103  -1.141  -1.061  -1.202  -1.224  -1.075  -1.065  -1.096  -0.967
120   L         1.328   1.349   1.420   1.193   1.221   1.344   1.428   1.460   1.569
121   P        -0.188  -0.040  -0.418  -0.089   0.110  -0.484  -0.185   0.013  -0.501
122   T        -1.479  -1.447  -1.467  -1.358  -1.308  -1.388  -1.211  -1.181  -1.144
123   E        -1.622  -1.545  -1.483  -1.559  -1.453  -1.367  -1.358  -1.282  -1.160
124   D         0.547   0.628   0.332   0.658   0.765   0.351   0.548   0.668   0.173
125   S        -1.103  -1.121  -1.063  -0.983  -0.976  -0.876  -1.065  -1.072  -0.967
126   E        -0.188  -0.156  -0.431  -0.007   0.036  -0.382  -0.185  -0.142  -0.519
127   M        -0.188  -0.156  -0.431  -0.022   0.020  -0.385  -0.185  -0.142  -0.519
128   G         1.328   1.349   1.420   1.267   1.296   1.414   1.428   1.460   1.569
129   L         1.328   1.349   1.420   1.193   1.221   1.344   1.428   1.460   1.569
130   V        -1.103  -1.156  -1.069  -1.018  -1.070  -0.947  -1.065  -1.113  -0.975
131   L        -1.103  -1.119  -1.059  -1.157  -1.177  -1.081  -1.065  -1.076  -0.965
132   A         1.328   1.349   1.420   1.369   1.386   1.510   1.428   1.460   1.569
133   S         1.328   1.349   1.420   1.346   1.380   1.488   1.428   1.460   1.569
134   A         0.028   0.089   0.168   0.008   0.081   0.218  -0.332  -0.228  -0.125
135   L        -0.491  -0.500  -0.528  -0.652  -0.684  -0.689  -0.625  -0.653  -0.657
136   F         0.547   0.602   0.326   0.496   0.567   0.184   0.548   0.629   0.162
137   A         0.189   0.252   0.215   0.116   0.222   0.127  -0.038   0.065  -0.038
138   K         1.328   1.349   1.420   1.096   1.133   1.252   1.428   1.460   1.569
139   F         0.547   0.546   0.324   0.692   0.699   0.385   0.548   0.545   0.158
140   V        -0.188  -0.300  -0.463  -0.015  -0.212  -0.451  -0.185  -0.346  -0.562
141   T         0.547   0.389   0.296   0.646   0.435   0.263   0.548   0.297   0.109
142   P         0.547   0.389   0.296   0.645   0.422   0.267   0.548   0.297   0.109
143   K         0.547   0.389   0.296   0.395   0.185   0.039   0.548   0.297   0.109
144   G         0.547   0.389   0.296   0.570   0.348   0.201   0.548   0.297   0.109
145   S        -0.583  -0.659  -0.539  -0.645  -0.736  -0.556  -0.772  -0.841  -0.672
146   N        -0.188  -0.300  -0.463  -0.025  -0.219  -0.518  -0.185  -0.346  -0.562
147   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
148   V         1.328   1.349   1.420   1.371   1.399   1.513   1.428   1.460   1.569
149   V        -0.491  -0.596  -0.530  -0.533  -0.707  -0.631  -0.625  -0.748  -0.658
150   R         1.328   1.349   1.420   1.588   1.610   1.718   1.428   1.460   1.569
151   P         1.328   1.349   1.420   1.343   1.369   1.486   1.428   1.460   1.569
152   Y         1.328   1.349   1.420   1.493   1.521   1.629   1.428   1.460   1.569
153   T         1.328   1.349   1.420   1.348   1.389   1.491   1.428   1.460   1.569
154   P         1.328   1.349   1.420   1.343   1.369   1.486   1.428   1.460   1.569
155   V         0.189   0.151   0.178   0.136   0.059   0.072  -0.038  -0.114  -0.108
156   S         1.328   1.349   1.420   1.346   1.380   1.488   1.428   1.460   1.569
157   D         1.328   1.349   1.420   1.348   1.380   1.491   1.428   1.460   1.569
158   L        -1.622  -1.640  -1.505  -1.615  -1.642  -1.426  -1.358  -1.361  -1.178
159   S        -1.103  -0.998  -1.049  -1.102  -0.944  -1.023  -1.065  -0.948  -0.954
160   Q        -1.999  -1.978  -1.833  -1.720  -1.706  -1.521  -1.505  -1.479  -1.290
161   K        -0.188  -0.272  -0.452  -0.257  -0.361  -0.602  -0.185  -0.311  -0.546
162   G         1.328   1.349   1.420   1.267   1.296   1.414   1.428   1.460   1.569
163   H        -1.622  -1.525  -1.488  -1.445  -1.297  -1.266  -1.358  -1.267  -1.164
164   F        -0.491  -0.430  -0.508  -0.442  -0.359  -0.445  -0.625  -0.547  -0.628
165   Q        -0.491  -0.492  -0.520  -0.441  -0.471  -0.487  -0.625  -0.641  -0.647
166   L         0.028   0.085   0.168  -0.308  -0.217  -0.083  -0.332  -0.236  -0.126
167   V         0.547   0.389   0.296   0.645   0.409   0.227   0.548   0.297   0.109
168   V         0.028   0.085   0.168  -0.164  -0.066   0.053  -0.332  -0.236  -0.126
169   K         1.328   1.349   1.420   1.096   1.133   1.252   1.428   1.460   1.569
170   H        -0.583  -0.571  -0.537  -0.726  -0.718  -0.648  -0.772  -0.747  -0.669
171   Y         1.328   1.349   1.420   1.493   1.521   1.629   1.428   1.460   1.569
172   E        -0.491  -0.428  -0.495  -0.479  -0.370  -0.495  -0.625  -0.526  -0.608
173   G        -0.188  -0.146  -0.425  -0.096  -0.043  -0.437  -0.185  -0.129  -0.510
174   G         1.328   1.349   1.420   1.267   1.296   1.414   1.428   1.460   1.569
175   K         0.547   0.389   0.296   0.394   0.182   0.037   0.548   0.297   0.109
176   M         0.547   0.613   0.328   0.896   0.980   0.548   0.548   0.645   0.164
177   T         0.028   0.071   0.163  -0.195  -0.114   0.014  -0.332  -0.262  -0.135
178   S        -0.868  -0.973  -1.031  -0.764  -0.932  -1.083  -0.772  -0.896  -0.931
179   H         0.547   0.389   0.296   0.877   0.665   0.503   0.548   0.297   0.109
180   L         0.028   0.072   0.170  -0.311  -0.243  -0.083  -0.332  -0.259  -0.123
181   F         0.028   0.034   0.152  -0.047  -0.031   0.148  -0.332  -0.330  -0.156
182   G        -1.103  -1.056  -1.058  -1.080  -1.004  -0.989  -1.065  -1.004  -0.963
183   L         0.547   0.389   0.296   0.536   0.336   0.228   0.548   0.297   0.109
184   K         0.547   0.389   0.296   0.398   0.186   0.048   0.548   0.297   0.109
185   P         0.028   0.065   0.160  -0.167  -0.113   0.037  -0.332  -0.273  -0.141
186   N        -0.583  -0.533  -0.527  -0.773  -0.705  -0.703  -0.772  -0.706  -0.658
187   D        -0.188  -0.272  -0.452   0.003  -0.114  -0.373  -0.185  -0.311  -0.546
188   T         0.547   0.389   0.296   0.688   0.496   0.360   0.548   0.297   0.109
189   V         0.189   0.252   0.215  -0.031   0.065  -0.002  -0.038   0.065  -0.038
190   S        -0.491  -0.562  -0.520  -0.515  -0.612  -0.570  -0.625  -0.698  -0.645
191   F         0.547   0.389   0.296   0.670   0.457   0.290   0.548   0.297   0.109
192   K         0.547   0.596   0.327   0.424   0.494   0.152   0.548   0.620   0.163
193   G         1.328   1.349   1.420   1.267   1.296   1.414   1.428   1.460   1.569
194   P         1.328   1.349   1.420   1.343   1.369   1.486   1.428   1.460   1.569
195   I        -0.188  -0.256  -0.452  -0.049  -0.176  -0.491  -0.185  -0.291  -0.547
196   M        -1.622  -1.561  -1.493  -1.461  -1.383  -1.259  -1.358  -1.293  -1.167
197   K         1.328   1.349   1.420   1.096   1.133   1.252   1.428   1.460   1.569
198   W         0.189   0.115   0.170   0.403   0.262   0.312  -0.038  -0.180  -0.121
199   K        -1.103  -1.150  -1.064  -1.199  -1.256  -1.092  -1.065  -1.108  -0.970
200   W         1.328   1.349   1.420   1.605   1.636   1.735   1.428   1.460   1.569
201   Q        -0.726  -0.682  -0.578  -0.895  -0.813  -0.677  -0.918  -0.859  -0.716
202   P         0.547   0.389   0.296   0.646   0.419   0.269   0.548   0.297   0.109
203   N         1.328   1.349   1.420   1.412   1.445   1.552   1.428   1.460   1.569
204   Q        -1.103  -1.175  -1.068  -1.070  -1.218  -1.093  -1.065  -1.126  -0.973
205   F        -0.726  -0.707  -0.584  -0.696  -0.657  -0.479  -0.918  -0.895  -0.724
206   K         0.189   0.249   0.211  -0.133  -0.033  -0.104  -0.038   0.059  -0.046
207   S        -0.868  -0.973  -1.031  -0.641  -0.778  -0.879  -0.772  -0.896  -0.931
208   I         1.328   1.349   1.420   1.364   1.396   1.505   1.428   1.460   1.569
209   T         0.028   0.041   0.154  -0.180  -0.167   0.010  -0.332  -0.318  -0.153
210   L         1.328   1.349   1.420   1.193   1.221   1.344   1.428   1.460   1.569
211   L        -0.583  -0.660  -0.548  -0.797  -0.892  -0.711  -0.772  -0.843  -0.682
212   G         0.547   0.389   0.296   0.570   0.348   0.201   0.548   0.297   0.109
213   A         0.028   0.060   0.160  -0.247  -0.207  -0.039  -0.332  -0.282  -0.142
214   G         1.328   1.349   1.420   1.267   1.296   1.414   1.428   1.460   1.569
215   T         1.328   1.349   1.420   1.348   1.389   1.491   1.428   1.460   1.569
216   G         1.328   1.349   1.420   1.267   1.296   1.414   1.428   1.460   1.569
217   I         1.328   1.349   1.420   1.364   1.396   1.505   1.428   1.460   1.569
218   N         0.189   0.252   0.215   0.133   0.242   0.149  -0.038   0.065  -0.038
219   P         1.328   1.349   1.420   1.343   1.369   1.486   1.428   1.460   1.569
220   L         0.547   0.389   0.296   0.536   0.336   0.228   0.548   0.297   0.109
221   Y         1.328   1.349   1.420   1.493   1.521   1.629   1.428   1.460   1.569
222   Q         1.328   1.349   1.420   1.511   1.543   1.645   1.428   1.460   1.569
223   L         1.328   1.349   1.420   1.193   1.221   1.344   1.428   1.460   1.569
224   A        -1.622  -1.512  -1.488  -1.496  -1.355  -1.300  -1.358  -1.255  -1.164
225   H        -0.188  -0.343  -0.467   0.210  -0.003  -0.220  -0.185  -0.399  -0.567
226   H        -1.103  -1.029  -1.066  -0.857  -0.805  -0.824  -1.065  -1.000  -0.973
227   I         1.328   1.349   1.420   1.364   1.396   1.505   1.428   1.460   1.569
228   V        -1.479  -1.521  -1.478  -1.278  -1.348  -1.297  -1.211  -1.250  -1.153
229   E        -1.622  -1.618  -1.500  -1.621  -1.604  -1.410  -1.358  -1.345  -1.174
230   N         1.328   1.349   1.420   1.412   1.445   1.552   1.428   1.460   1.569
231   P         0.547   0.596   0.327   0.601   0.665   0.224   0.548   0.620   0.163
232   N        -0.868  -0.908  -1.015  -0.697  -0.772  -0.986  -0.772  -0.826  -0.913
233   D         1.328   1.349   1.420   1.348   1.380   1.491   1.428   1.460   1.569
234   K         0.189   0.266   0.205  -0.107   0.019  -0.079  -0.038   0.090  -0.058
235   T         1.328   1.349   1.420   1.348   1.389   1.491   1.428   1.460   1.569
236   K         1.328   1.349   1.420   1.096   1.133   1.252   1.428   1.460   1.569
237   V         0.189   0.249   0.211   0.136   0.230   0.137  -0.038   0.059  -0.046
238   N        -0.188  -0.286  -0.459   0.065  -0.084  -0.332  -0.185  -0.328  -0.556
239   L         1.328   1.349   1.420   1.193   1.221   1.344   1.428   1.460   1.569
240   L        -1.479  -1.474  -1.463  -1.289  -1.295  -1.298  -1.211  -1.207  -1.140
241   Y         0.547   0.389   0.296   0.795   0.573   0.402   0.548   0.297   0.109
242   G         1.328   1.349   1.420   1.267   1.296   1.414   1.428   1.460   1.569
243   N         0.547   0.596   0.327   0.711   0.779   0.375   0.548   0.620   0.163
244   K        -1.103  -1.160  -1.076  -1.392  -1.454  -1.302  -1.065  -1.109  -0.980
245   T         0.547   0.389   0.296   0.647   0.438   0.264   0.548   0.297   0.109
246   P         0.028   0.034   0.152  -0.167  -0.169   0.023  -0.332  -0.330  -0.156
247   Q        -1.479  -1.381  -1.439  -1.322  -1.167  -1.314  -1.211  -1.107  -1.119
248   D         1.328   1.349   1.420   1.348   1.380   1.491   1.428   1.460   1.569
249   I         0.547   0.389   0.296   0.667   0.450   0.288   0.548   0.297   0.109
250   L         1.328   1.349   1.420   1.193   1.221   1.344   1.428   1.460   1.569
251   L         0.547   0.647   0.335   0.495   0.621   0.197   0.548   0.695   0.177
252   R         0.547   0.602   0.326   0.438   0.513   0.181   0.548   0.629   0.162
253   K        -0.868  -0.961  -1.025  -0.895  -1.004  -1.081  -0.772  -0.883  -0.925
254   E         1.328   1.349   1.420   1.397   1.425   1.537   1.428   1.460   1.569
255   L         0.189   0.229   0.208  -0.034   0.026  -0.018  -0.038   0.025  -0.051
256   D         0.547   0.389   0.296   0.651   0.431   0.273   0.548   0.297   0.109
257   A        -1.103  -1.059  -1.056  -1.060  -1.018  -0.992  -1.065  -1.023  -0.963
258   L         0.028   0.071   0.163  -0.276  -0.195  -0.066  -0.332  -0.262  -0.135
259   K        -1.103  -1.144  -1.077  -1.041  -1.108  -1.033  -1.065  -1.097  -0.983
260   E        -1.103  -1.118  -1.057  -1.262  -1.272  -1.150  -1.065  -1.071  -0.963
261   K        -0.188  -0.343  -0.467  -0.242  -0.438  -0.594  -0.185  -0.399  -0.567
262   Y        -0.491  -0.428  -0.495  -0.352  -0.254  -0.407  -0.625  -0.526  -0.608
263   P         0.189   0.286   0.237   0.008   0.178   0.038  -0.038   0.123   0.001
264   D        -0.491  -0.515  -0.530  -0.437  -0.484  -0.483  -0.625  -0.677  -0.659
265   K        -0.188  -0.295  -0.460   0.121  -0.022  -0.334  -0.185  -0.339  -0.558
266   F        -0.583  -0.530  -0.527  -0.706  -0.621  -0.623  -0.772  -0.701  -0.658
267   N        -0.491  -0.562  -0.518  -0.520  -0.580  -0.570  -0.625  -0.699  -0.642
268   V        -0.491  -0.575  -0.526  -0.490  -0.611  -0.553  -0.625  -0.716  -0.651
269   T        -1.622  -1.610  -1.500  -1.357  -1.343  -1.185  -1.358  -1.339  -1.174
270   Y         1.328   1.349   1.420   1.493   1.521   1.629   1.428   1.460   1.569
271   F         0.547   0.389   0.296   0.672   0.458   0.293   0.548   0.297   0.109
272   V         0.028   0.034   0.152  -0.269  -0.286  -0.095  -0.332  -0.330  -0.156
273   D         1.328   1.349   1.420   1.348   1.380   1.491   1.428   1.460   1.569
274   D        -0.188  -0.295  -0.460  -0.277  -0.422  -0.655  -0.185  -0.339  -0.558
275   K        -1.103  -1.073  -1.065  -1.150  -1.137  -1.131  -1.065  -1.040  -0.972
276   Q        -1.622  -1.568  -1.485  -1.495  -1.426  -1.287  -1.358  -1.301  -1.162
277   D        -1.622  -1.621  -1.501  -1.643  -1.683  -1.502  -1.358  -1.347  -1.174
278   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
279   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
280   D        -1.103  -1.140  -1.058  -1.166  -1.205  -1.110  -1.065  -1.093  -0.965
281   F         0.028   0.071   0.163   0.031   0.113   0.224  -0.332  -0.262  -0.135
282   D        -1.622  -1.627  -1.495  -1.585  -1.612  -1.417  -1.358  -1.352  -1.170
283   G         1.328   1.349   1.420   1.267   1.296   1.414   1.428   1.460   1.569
284   E        -0.491  -0.480  -0.522  -0.412  -0.429  -0.453  -0.625  -0.633  -0.649
285   I        -1.245  -1.213  -1.091  -1.442  -1.407  -1.199  -1.211  -1.168  -0.998
286   S         0.547   0.602   0.326   0.566   0.638   0.243   0.548   0.629   0.162
287   F         0.189   0.151   0.178   0.183   0.119   0.143  -0.038  -0.114  -0.108
288   I         1.328   1.349   1.420   1.364   1.396   1.505   1.428   1.460   1.569
289   S        -0.583  -0.660  -0.534  -0.687  -0.768  -0.585  -0.772  -0.842  -0.666
290   K         0.547   0.546   0.324   0.403   0.412   0.104   0.548   0.545   0.158
291   D         0.028   0.072   0.170  -0.162  -0.090   0.058  -0.332  -0.259  -0.123
292   F        -0.188  -0.286  -0.459  -0.020  -0.184  -0.451  -0.185  -0.328  -0.556
293   I         0.189   0.216   0.199  -0.034   0.005  -0.034  -0.038   0.002  -0.068
294   Q        -1.103  -1.067  -1.061  -1.089  -1.104  -1.070  -1.065  -1.034  -0.968
295   E        -1.999  -1.975  -1.836  -1.970  -1.931  -1.703  -1.505  -1.478  -1.292
296   H        -1.999  -1.945  -1.834  -1.715  -1.641  -1.496  -1.505  -1.455  -1.291
297   V        -1.103  -1.054  -1.058  -1.209  -1.147  -1.120  -1.065  -1.002  -0.963
298   P         0.547   0.628   0.332   0.650   0.750   0.341   0.548   0.668   0.173
299   G        -1.103  -1.168  -1.061  -1.288  -1.367  -1.211  -1.065  -1.118  -0.967
300   P         0.547   0.546   0.324   0.646   0.640   0.316   0.548   0.545   0.158
301   K        -1.103  -1.027  -1.048  -1.361  -1.235  -1.246  -1.065  -0.968  -0.952
302   E        -1.103  -1.124  -1.073  -1.106  -1.129  -1.097  -1.065  -1.083  -0.979
303   S        -1.103  -1.144  -1.077  -1.223  -1.269  -1.185  -1.065  -1.097  -0.983
304   T        -1.103  -1.130  -1.060  -1.036  -1.075  -0.981  -1.065  -1.086  -0.966
305   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
306   H        -0.491  -0.413  -0.511  -0.625  -0.514  -0.587  -0.625  -0.517  -0.632
307   L        -0.188  -0.295  -0.460  -0.043  -0.208  -0.503  -0.185  -0.339  -0.558
308   F         1.328   1.349   1.420   1.369   1.404   1.510   1.428   1.460   1.569
309   V         1.328   1.349   1.420   1.371   1.399   1.513   1.428   1.460   1.569
310   C         1.328   1.349   1.420   1.645   1.675   1.772   1.428   1.460   1.569
311   G         1.328   1.349   1.420   1.267   1.296   1.414   1.428   1.460   1.569
312   P         1.328   1.349   1.420   1.343   1.369   1.486   1.428   1.460   1.569
313   P         1.328   1.349   1.420   1.343   1.369   1.486   1.428   1.460   1.569
314   P         0.028   0.041   0.154  -0.247  -0.242  -0.060  -0.332  -0.318  -0.153
315   F        -0.491  -0.549  -0.514  -0.515  -0.550  -0.526  -0.625  -0.679  -0.634
316   M         0.028   0.072   0.170   0.096   0.167   0.303  -0.332  -0.259  -0.123
317   N        -0.491  -0.503  -0.528  -0.724  -0.741  -0.738  -0.625  -0.657  -0.657
318   A         0.189   0.132   0.173   0.127   0.006   0.050  -0.038  -0.148  -0.117
319   Y        -0.726  -0.652  -0.570  -0.882  -0.757  -0.659  -0.918  -0.818  -0.707
320   S         1.328   1.349   1.420   1.346   1.380   1.488   1.428   1.460   1.569
321   G         1.328   1.349   1.420   1.267   1.296   1.414   1.428   1.460   1.569
322   E        -1.479  -1.531  -1.480  -1.232  -1.325  -1.235  -1.211  -1.258  -1.155
323   K         1.328   1.349   1.420   1.096   1.133   1.252   1.428   1.460   1.569
324   K         0.028   0.065   0.160  -0.387  -0.329  -0.166  -0.332  -0.273  -0.141
325   S         1.328   1.349   1.420   1.346   1.380   1.488   1.428   1.460   1.569
326   P         1.328   1.349   1.420   1.343   1.369   1.486   1.428   1.460   1.569
327   K        -1.479  -1.493  -1.486  -1.193  -1.195  -1.192  -1.211  -1.224  -1.160
328   D         0.547   0.596   0.327   0.655   0.722   0.336   0.548   0.620   0.163
329   Q         1.328   1.349   1.420   1.511   1.543   1.645   1.428   1.460   1.569
330   G         1.328   1.349   1.420   1.267   1.296   1.414   1.428   1.460   1.569
331   E         0.547   0.596   0.327   0.696   0.759   0.362   0.548   0.620   0.163
332   L         0.189   0.239   0.211  -0.031   0.043  -0.009  -0.038   0.041  -0.045
333   I        -0.868  -0.775  -0.987  -0.686  -0.547  -0.885  -0.772  -0.660  -0.883
334   G         1.328   1.349   1.420   1.267   1.296   1.414   1.428   1.460   1.569
335   I         0.028   0.036   0.152  -0.166  -0.172   0.018  -0.332  -0.328  -0.157
336   L         1.328   1.349   1.420   1.193   1.221   1.344   1.428   1.460   1.569
337   N        -0.491  -0.390  -0.498  -0.730  -0.578  -0.706  -0.625  -0.482  -0.616
338   N        -0.726  -0.725  -0.587  -0.833  -0.835  -0.626  -0.918  -0.916  -0.729
339   L         1.328   1.349   1.420   1.193   1.221   1.344   1.428   1.460   1.569
340   G         1.328   1.349   1.420   1.267   1.296   1.414   1.428   1.460   1.569
341   Y         0.189   0.229   0.208   0.253   0.315   0.236  -0.038   0.025  -0.051
342   S        -0.868  -0.754  -0.996  -0.676  -0.512  -0.883  -0.772  -0.636  -0.893
343   K        -0.188  -0.300  -0.463  -0.257  -0.419  -0.619  -0.185  -0.346  -0.562
344   D        -0.491  -0.374  -0.489  -0.501  -0.318  -0.500  -0.625  -0.460  -0.601
345   Q        -0.491  -0.369  -0.500  -0.301  -0.115  -0.315  -0.625  -0.457  -0.618
346   V         1.328   1.349   1.420   1.371   1.399   1.513   1.428   1.460   1.569
347   F         0.547   0.389   0.296   0.692   0.488   0.340   0.548   0.297   0.109
348   K         1.328   1.349   1.420   1.096   1.133   1.252   1.428   1.460   1.569
349   F         1.328   1.349   1.420   1.369   1.404   1.510   1.428   1.460   1.569
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P36060
Output conservation file - output/P36060
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
