1     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    M        -0.281  -0.281  -0.235  -0.110  -0.114  -0.061  -0.546  -0.546  -0.480
15    L        -0.281  -0.281  -0.235  -0.510  -0.516  -0.434  -0.546  -0.546  -0.480
16    Q         1.035   1.038   1.060   1.052   1.058   1.092   1.093   1.098   1.127
17    F         1.035   1.038   1.060   1.177   1.181   1.210   1.093   1.098   1.127
18    K         1.035   1.038   1.060   0.973   0.978   1.018   1.093   1.098   1.127
19    L         1.035   1.038   1.060   0.959   0.961   1.004   1.093   1.098   1.127
20    V         1.035   1.038   1.060   0.949   0.952   0.995   1.093   1.098   1.127
21    L         1.035   1.038   1.060   0.959   0.961   1.004   1.093   1.098   1.127
22    L         1.035   1.038   1.060   0.959   0.961   1.004   1.093   1.098   1.127
23    G         1.035   1.038   1.060   1.062   1.070   1.101   1.093   1.098   1.127
24    D        -0.281  -0.281  -0.235  -0.482  -0.487  -0.414  -0.546  -0.546  -0.480
25    S         1.035   1.038   1.060   0.904   0.920   0.952   1.093   1.098   1.127
26    S        -0.281  -0.281  -0.235  -0.558  -0.551  -0.476  -0.546  -0.546  -0.480
27    V         1.035   1.038   1.060   0.949   0.952   0.995   1.093   1.098   1.127
28    G         1.035   1.038   1.060   1.062   1.070   1.101   1.093   1.098   1.127
29    K         1.035   1.038   1.060   0.973   0.978   1.018   1.093   1.098   1.127
30    S         1.035   1.038   1.060   0.904   0.920   0.952   1.093   1.098   1.127
31    S         1.035   1.038   1.060   0.904   0.920   0.952   1.093   1.098   1.127
32    I         1.035   1.038   1.060   1.072   1.078   1.111   1.093   1.098   1.127
33    V         1.035   1.038   1.060   0.949   0.952   0.995   1.093   1.098   1.127
34    H         1.035   1.038   1.060   1.327   1.332   1.352   1.093   1.098   1.127
35    R         1.035   1.038   1.060   1.110   1.114   1.147   1.093   1.098   1.127
36    F         1.035   1.038   1.060   1.177   1.181   1.210   1.093   1.098   1.127
37    V         1.035   1.038   1.060   0.949   0.952   0.995   1.093   1.098   1.127
38    K         1.035   1.038   1.060   0.973   0.978   1.018   1.093   1.098   1.127
39    D        -0.281  -0.281  -0.235  -0.389  -0.393  -0.313  -0.546  -0.546  -0.480
40    T         0.057   0.014  -0.156   0.180   0.118  -0.189   0.001  -0.065  -0.346
41    F         1.035   1.038   1.060   1.177   1.181   1.210   1.093   1.098   1.127
42    D         1.035   1.038   1.060   1.013   1.018   1.055   1.093   1.098   1.127
43    E        -0.823  -0.828  -0.964  -0.783  -0.794  -0.988  -0.819  -0.825  -0.985
44    L        -1.027  -1.046  -0.996  -0.869  -0.886  -0.805  -1.092  -1.108  -1.024
45    R         1.035   1.038   1.060   1.110   1.114   1.147   1.093   1.098   1.127
46    E         1.035   1.038   1.060   0.954   0.957   0.999   1.093   1.098   1.127
47    S         1.035   1.038   1.060   0.904   0.920   0.952   1.093   1.098   1.127
48    T         1.035   1.038   1.060   1.120   1.126   1.156   1.093   1.098   1.127
49    I         1.035   1.038   1.060   1.072   1.078   1.111   1.093   1.098   1.127
50    G         1.035   1.038   1.060   1.062   1.070   1.101   1.093   1.098   1.127
51    A         1.035   1.038   1.060   0.988   0.992   1.032   1.093   1.098   1.127
52    A         1.035   1.038   1.060   0.988   0.992   1.032   1.093   1.098   1.127
53    F         1.035   1.038   1.060   1.177   1.181   1.210   1.093   1.098   1.127
54    L         1.035   1.038   1.060   0.959   0.961   1.004   1.093   1.098   1.127
55    S        -0.281  -0.281  -0.235  -0.479  -0.471  -0.392  -0.546  -0.546  -0.480
56    Q         1.035   1.038   1.060   1.052   1.058   1.092   1.093   1.098   1.127
57    S        -0.281  -0.273  -0.239  -0.417  -0.397  -0.373  -0.546  -0.533  -0.487
58    I         0.057   0.073  -0.153   0.143   0.167  -0.205   0.001   0.026  -0.340
59    T        -0.281  -0.287  -0.234  -0.378  -0.395  -0.316  -0.546  -0.557  -0.477
60    I        -0.281  -0.298  -0.242  -0.428  -0.468  -0.382  -0.546  -0.575  -0.492
61    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
62    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
63    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
64    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
65    G        -1.569  -1.558  -1.538  -1.348  -1.333  -1.365  -1.366  -1.351  -1.298
66    N        -0.823  -0.770  -0.946  -0.783  -0.713  -0.961  -0.819  -0.751  -0.963
67    E        -0.209  -0.192  -0.225  -0.335  -0.306  -0.354  -0.424  -0.394  -0.463
68    T        -1.113  -1.106  -1.007  -0.992  -0.979  -0.837  -1.183  -1.173  -1.037
69    K        -2.111  -2.105  -1.969  -2.056  -2.038  -1.841  -1.639  -1.630  -1.470
70    D        -1.027  -1.038  -0.984  -1.113  -1.131  -1.021  -1.092  -1.100  -1.011
71    V        -1.027  -1.046  -0.996  -1.062  -1.084  -1.001  -1.092  -1.108  -1.024
72    V        -0.281  -0.281  -0.235  -0.441  -0.444  -0.358  -0.546  -0.546  -0.480
73    I        -0.823  -0.879  -0.946  -0.741  -0.836  -0.972  -0.819  -0.889  -0.963
74    K         1.035   1.038   1.060   0.973   0.978   1.018   1.093   1.098   1.127
75    F         1.035   1.038   1.060   1.177   1.181   1.210   1.093   1.098   1.127
76    E         1.035   1.038   1.060   0.954   0.957   0.999   1.093   1.098   1.127
77    I         1.035   1.038   1.060   1.072   1.078   1.111   1.093   1.098   1.127
78    W         1.035   1.038   1.060   1.309   1.314   1.334   1.093   1.098   1.127
79    D         1.035   1.038   1.060   1.013   1.018   1.055   1.093   1.098   1.127
80    T         1.035   1.038   1.060   1.120   1.126   1.156   1.093   1.098   1.127
81    A         1.035   1.038   1.060   0.988   0.992   1.032   1.093   1.098   1.127
82    G         1.035   1.038   1.060   1.062   1.070   1.101   1.093   1.098   1.127
83    Q         1.035   1.038   1.060   1.052   1.058   1.092   1.093   1.098   1.127
84    E         1.035   1.038   1.060   0.954   0.957   0.999   1.093   1.098   1.127
85    R         1.035   1.038   1.060   1.110   1.114   1.147   1.093   1.098   1.127
86    Y         1.035   1.038   1.060   1.210   1.215   1.242   1.093   1.098   1.127
87    K         1.035   1.038   1.060   0.973   0.978   1.018   1.093   1.098   1.127
88    S         1.035   1.038   1.060   0.904   0.920   0.952   1.093   1.098   1.127
89    L         1.035   1.038   1.060   0.959   0.961   1.004   1.093   1.098   1.127
90    A         1.035   1.038   1.060   0.988   0.992   1.032   1.093   1.098   1.127
91    P         1.035   1.038   1.060   1.253   1.257   1.282   1.093   1.098   1.127
92    M         1.035   1.038   1.060   1.304   1.309   1.330   1.093   1.098   1.127
93    Y         1.035   1.038   1.060   1.210   1.215   1.242   1.093   1.098   1.127
94    Y         1.035   1.038   1.060   1.210   1.215   1.242   1.093   1.098   1.127
95    R         1.035   1.038   1.060   1.110   1.114   1.147   1.093   1.098   1.127
96    N         1.035   1.038   1.060   1.115   1.118   1.152   1.093   1.098   1.127
97    A         1.035   1.038   1.060   0.988   0.992   1.032   1.093   1.098   1.127
98    N         1.035   1.038   1.060   1.115   1.118   1.152   1.093   1.098   1.127
99    A         1.035   1.038   1.060   0.988   0.992   1.032   1.093   1.098   1.127
100   A         1.035   1.038   1.060   0.988   0.992   1.032   1.093   1.098   1.127
101   L         1.035   1.038   1.060   0.959   0.961   1.004   1.093   1.098   1.127
102   V        -0.281  -0.281  -0.235  -0.349  -0.351  -0.259  -0.546  -0.546  -0.480
103   V         1.035   1.038   1.060   0.949   0.952   0.995   1.093   1.098   1.127
104   Y         1.035   1.038   1.060   1.210   1.215   1.242   1.093   1.098   1.127
105   D         1.035   1.038   1.060   1.013   1.018   1.055   1.093   1.098   1.127
106   I        -0.281  -0.287  -0.234  -0.434  -0.451  -0.368  -0.546  -0.557  -0.477
107   T         1.035   1.038   1.060   1.120   1.126   1.156   1.093   1.098   1.127
108   Q        -1.027  -1.046  -0.996  -1.180  -1.204  -1.121  -1.092  -1.108  -1.024
109   E        -1.027  -0.999  -0.993  -0.891  -0.852  -0.856  -1.092  -1.062  -1.021
110   D        -0.281  -0.281  -0.235  -0.511  -0.508  -0.445  -0.546  -0.546  -0.480
111   S         1.035   1.038   1.060   0.904   0.920   0.952   1.093   1.098   1.127
112   L        -0.281  -0.281  -0.235  -0.399  -0.403  -0.314  -0.546  -0.546  -0.480
113   Q        -1.569  -1.596  -1.522  -1.376  -1.404  -1.305  -1.366  -1.389  -1.283
114   K         1.035   1.038   1.060   0.973   0.978   1.018   1.093   1.098   1.127
115   A         1.035   1.038   1.060   0.988   0.992   1.032   1.093   1.098   1.127
116   R        -0.823  -0.818  -0.946  -0.704  -0.705  -0.906  -0.819  -0.813  -0.963
117   N        -1.569  -1.558  -1.538  -1.534  -1.521  -1.499  -1.366  -1.351  -1.298
118   W         1.035   1.038   1.060   1.309   1.314   1.334   1.093   1.098   1.127
119   V        -0.281  -0.281  -0.235  -0.469  -0.472  -0.389  -0.546  -0.546  -0.480
120   D        -1.027  -1.018  -0.994  -1.122  -1.111  -1.049  -1.092  -1.080  -1.022
121   E         1.035   1.038   1.060   0.954   0.957   0.999   1.093   1.098   1.127
122   L         1.035   1.038   1.060   0.959   0.961   1.004   1.093   1.098   1.127
123   K         0.057   0.073  -0.153   0.071   0.093  -0.243   0.001   0.026  -0.340
124   N        -0.209  -0.243  -0.230  -0.256  -0.326  -0.328  -0.424  -0.481  -0.471
125   K         1.035   1.038   1.060   0.973   0.978   1.018   1.093   1.098   1.127
126   V        -0.281  -0.281  -0.235  -0.481  -0.484  -0.401  -0.546  -0.546  -0.480
127   G        -1.027  -1.046  -0.996  -1.054  -1.080  -0.981  -1.092  -1.108  -1.024
128   D        -0.281  -0.281  -0.235  -0.309  -0.311  -0.227  -0.546  -0.546  -0.480
129   D        -0.281  -0.278  -0.232  -0.500  -0.499  -0.416  -0.546  -0.541  -0.474
130   D        -1.569  -1.558  -1.538  -1.509  -1.494  -1.487  -1.366  -1.351  -1.298
131   L        -0.281  -0.281  -0.235  -0.461  -0.465  -0.381  -0.546  -0.546  -0.480
132   V         0.057   0.014  -0.156   0.052  -0.010  -0.261   0.001  -0.065  -0.346
133   I         1.035   1.038   1.060   1.072   1.078   1.111   1.093   1.098   1.127
134   Y        -1.027  -1.011  -0.981  -0.796  -0.770  -0.744  -1.092  -1.072  -1.007
135   L         1.035   1.038   1.060   0.959   0.961   1.004   1.093   1.098   1.127
136   L         0.057   0.108  -0.151   0.023   0.093  -0.305   0.001   0.077  -0.338
137   G         1.035   1.038   1.060   1.062   1.070   1.101   1.093   1.098   1.127
138   N         1.035   1.038   1.060   1.115   1.118   1.152   1.093   1.098   1.127
139   K         1.035   1.038   1.060   0.973   0.978   1.018   1.093   1.098   1.127
140   V        -1.569  -1.593  -1.537  -1.647  -1.687  -1.606  -1.366  -1.386  -1.297
141   D         1.035   1.038   1.060   1.013   1.018   1.055   1.093   1.098   1.127
142   L         0.057   0.073  -0.153   0.062   0.082  -0.247   0.001   0.026  -0.340
143   C        -0.209  -0.179  -0.224  -0.242  -0.199  -0.235  -0.424  -0.373  -0.461
144   Q        -1.113  -1.106  -1.007  -1.319  -1.316  -1.145  -1.183  -1.173  -1.037
145   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
146   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
147   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
148   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
149   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
150   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
151   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
152   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
153   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
154   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
155   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
156   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
157   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
158   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
159   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
160   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
161   E        -0.209  -0.192  -0.225  -0.361  -0.333  -0.388  -0.424  -0.394  -0.463
162   E        -1.113  -1.106  -1.007  -1.195  -1.175  -1.029  -1.183  -1.173  -1.037
163   Q        -0.823  -0.765  -0.935  -0.804  -0.722  -0.974  -0.819  -0.743  -0.949
164   K        -1.569  -1.546  -1.532  -1.647  -1.606  -1.583  -1.366  -1.340  -1.292
165   V        -2.111  -2.105  -1.969  -1.965  -1.950  -1.755  -1.639  -1.630  -1.470
166   R         0.057   0.014  -0.156   0.171   0.107  -0.198   0.001  -0.065  -0.346
167   A        -1.569  -1.558  -1.538  -1.612  -1.602  -1.568  -1.366  -1.351  -1.298
168   I        -0.281  -0.258  -0.227  -0.469  -0.434  -0.377  -0.546  -0.507  -0.467
169   S        -1.027  -0.997  -0.977  -1.191  -1.142  -1.107  -1.092  -1.059  -1.004
170   T        -1.027  -1.011  -0.981  -1.112  -1.092  -1.051  -1.092  -1.072  -1.007
171   E        -1.569  -1.593  -1.537  -1.575  -1.610  -1.523  -1.366  -1.386  -1.297
172   E         0.057   0.014  -0.156   0.042  -0.022  -0.284   0.001  -0.065  -0.346
173   A        -1.027  -1.018  -0.994  -1.154  -1.145  -1.076  -1.092  -1.080  -1.022
174   K        -2.111  -2.105  -1.969  -2.018  -2.004  -1.805  -1.639  -1.630  -1.470
175   Q        -0.281  -0.273  -0.239  -0.477  -0.467  -0.403  -0.546  -0.533  -0.487
176   Y         0.057   0.014  -0.156   0.334   0.275   0.009   0.001  -0.065  -0.346
177   A        -0.823  -0.828  -0.964  -0.785  -0.796  -1.015  -0.819  -0.825  -0.985
178   Q         0.057   0.029  -0.154   0.139   0.100  -0.196   0.001  -0.041  -0.343
179   E         0.057   0.073  -0.153   0.036   0.056  -0.290   0.001   0.026  -0.340
180   Q        -0.823  -0.879  -0.946  -0.707  -0.796  -0.911  -0.819  -0.889  -0.963
181   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
182   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
183   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
184   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
185   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
186   G        -1.569  -1.554  -1.517  -1.524  -1.497  -1.442  -1.366  -1.348  -1.278
187   L        -0.823  -0.828  -0.964  -0.698  -0.705  -0.863  -0.819  -0.825  -0.985
188   L        -0.823  -0.828  -0.964  -0.814  -0.828  -1.037  -0.819  -0.825  -0.985
189   F        -0.823  -0.828  -0.964  -0.579  -0.593  -0.832  -0.819  -0.825  -0.985
190   R        -1.569  -1.558  -1.538  -1.372  -1.352  -1.299  -1.366  -1.351  -1.298
191   E         0.057   0.014  -0.156   0.052  -0.011  -0.265   0.001  -0.065  -0.346
192   V        -0.281  -0.281  -0.235  -0.349  -0.351  -0.259  -0.546  -0.546  -0.480
193   S         1.035   1.038   1.060   0.904   0.920   0.952   1.093   1.098   1.127
194   A         1.035   1.038   1.060   0.988   0.992   1.032   1.093   1.098   1.127
195   K         1.035   1.038   1.060   0.973   0.978   1.018   1.093   1.098   1.127
196   T        -0.281  -0.281  -0.235  -0.417  -0.414  -0.362  -0.546  -0.546  -0.480
197   G         1.035   1.038   1.060   1.062   1.070   1.101   1.093   1.098   1.127
198   E        -1.027  -1.018  -0.994  -1.160  -1.150  -1.095  -1.092  -1.080  -1.022
199   G         0.057   0.014  -0.156   0.174   0.116  -0.144   0.001  -0.065  -0.346
200   V         1.035   1.038   1.060   0.949   0.952   0.995   1.093   1.098   1.127
201   K        -1.569  -1.593  -1.537  -1.568  -1.610  -1.523  -1.366  -1.386  -1.297
202   E        -0.823  -0.818  -0.946  -0.791  -0.788  -1.010  -0.819  -0.813  -0.963
203   I        -0.281  -0.286  -0.239  -0.434  -0.447  -0.382  -0.546  -0.554  -0.488
204   F         1.035   1.038   1.060   1.177   1.181   1.210   1.093   1.098   1.127
205   Q        -0.823  -0.828  -0.964  -0.657  -0.666  -0.864  -0.819  -0.825  -0.985
206   D        -1.027  -1.018  -0.994  -1.158  -1.147  -1.098  -1.092  -1.080  -1.022
207   I         0.057   0.029  -0.154   0.143   0.102  -0.208   0.001  -0.041  -0.343
208   G         0.057   0.029  -0.154   0.143   0.104  -0.199   0.001  -0.041  -0.343
209   E        -0.281  -0.281  -0.235  -0.443  -0.447  -0.360  -0.546  -0.546  -0.480
210   K        -1.569  -1.558  -1.538  -1.489  -1.472  -1.436  -1.366  -1.351  -1.298
211   L         1.035   1.038   1.060   0.959   0.961   1.004   1.093   1.098   1.127
212   Y        -0.281  -0.281  -0.235  -0.146  -0.149  -0.084  -0.546  -0.546  -0.480
213   D        -1.569  -1.558  -1.538  -1.636  -1.619  -1.595  -1.366  -1.351  -1.298
214   L        -2.111  -2.105  -1.969  -1.981  -1.974  -1.770  -1.639  -1.630  -1.470
215   K        -1.027  -1.046  -0.996  -1.142  -1.168  -1.058  -1.092  -1.108  -1.024
216   K        -0.281  -0.281  -0.235  -0.520  -0.525  -0.447  -0.546  -0.546  -0.480
217   D        -1.027  -1.018  -0.994  -1.075  -1.062  -1.020  -1.092  -1.080  -1.022
218   E        -1.569  -1.554  -1.517  -1.647  -1.617  -1.561  -1.366  -1.348  -1.278
219   I        -1.569  -1.565  -1.533  -1.472  -1.465  -1.437  -1.366  -1.358  -1.293
220   L        -0.998  -1.007  -0.995  -1.166  -1.156  -1.150  -1.041  -1.051  -1.023
221   S        -0.998  -0.986  -0.973  -1.078  -1.019  -1.018  -1.041  -1.025  -0.996
222   K        -0.998  -0.981  -0.994  -1.075  -1.026  -1.079  -1.041  -1.018  -1.021
223   -        -0.209  -0.282  -0.231  -0.249  -0.375  -0.303  -0.424  -0.548  -0.473
224   Q         0.057   0.029  -0.154   0.165   0.126  -0.150   0.001  -0.041  -0.343
225   N        -2.111  -2.105  -1.969  -1.955  -1.948  -1.745  -1.639  -1.630  -1.470
226   R        -0.998  -0.981  -0.994  -0.974  -0.942  -0.994  -1.041  -1.018  -1.021
227   Q        -1.113  -1.095  -1.007  -1.142  -1.127  -0.978  -1.183  -1.159  -1.037
228   I        -1.675  -1.671  -1.549  -1.478  -1.477  -1.295  -1.468  -1.461  -1.308
229   G        -0.064  -0.080  -0.185  -0.055  -0.089  -0.262  -0.187  -0.212  -0.395
230   G        -1.027  -1.038  -0.985  -1.113  -1.122  -1.018  -1.092  -1.099  -1.013
231   G        -1.569  -1.558  -1.538  -1.450  -1.438  -1.434  -1.366  -1.351  -1.298
232   N        -1.569  -1.558  -1.538  -1.446  -1.432  -1.429  -1.366  -1.351  -1.298
233   N        -1.027  -0.999  -0.978  -0.975  -0.935  -0.890  -1.092  -1.062  -1.005
234   G        -0.281  -0.287  -0.234  -0.348  -0.360  -0.274  -0.546  -0.557  -0.477
235   Q        -1.569  -1.558  -1.538  -1.366  -1.349  -1.318  -1.366  -1.351  -1.298
236   V         0.057   0.014  -0.156   0.063   0.001  -0.240   0.001  -0.065  -0.346
237   D         0.057   0.014  -0.156   0.126   0.066  -0.185   0.001  -0.065  -0.346
238   I        -0.281  -0.281  -0.235  -0.428  -0.432  -0.366  -0.546  -0.546  -0.480
239   N        -1.569  -1.596  -1.522  -1.431  -1.480  -1.384  -1.366  -1.389  -1.283
240   L        -1.027  -1.018  -0.994  -1.038  -1.029  -0.966  -1.092  -1.080  -1.022
241   Q        -0.823  -0.828  -0.964  -0.654  -0.668  -0.860  -0.819  -0.825  -0.985
242   R         0.057   0.029  -0.154   0.191   0.148  -0.157   0.001  -0.041  -0.343
243   P        -0.823  -0.828  -0.964  -0.491  -0.501  -0.749  -0.819  -0.825  -0.985
244   S        -0.281  -0.281  -0.235  -0.520  -0.512  -0.435  -0.546  -0.546  -0.480
245   T        -0.823  -0.828  -0.964  -0.666  -0.675  -0.925  -0.819  -0.825  -0.985
246   N         0.057   0.029  -0.154   0.211   0.169  -0.124   0.001  -0.041  -0.343
247   D        -0.281  -0.281  -0.235  -0.426  -0.428  -0.352  -0.546  -0.546  -0.480
248   P        -1.569  -1.550  -1.519  -1.436  -1.410  -1.331  -1.366  -1.344  -1.280
249   T        -1.569  -1.554  -1.517  -1.495  -1.471  -1.394  -1.366  -1.348  -1.278
250   S         1.035   1.038   1.060   0.904   0.920   0.952   1.093   1.098   1.127
251   C         1.035   1.038   1.060   1.276   1.281   1.304   1.093   1.098   1.127
252   C         1.035   1.038   1.060   1.276   1.281   1.304   1.093   1.098   1.127
253   S         1.035   1.038   1.060   0.908   0.911   0.957   1.093   1.098   1.127
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P36018
Output conservation file - output/P36018
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
