1     M         1.286   1.305   1.337   1.559   1.594   1.633   1.361   1.384   1.426
2     -        -1.067  -1.042  -0.969  -1.304  -1.287  -1.134  -1.101  -1.057  -0.948
3     -        -0.077  -0.036  -0.060  -0.155  -0.073  -0.152  -0.281  -0.212  -0.258
4     -        -1.067  -1.042  -0.969  -0.978  -0.940  -0.818  -1.101  -1.057  -0.948
5     -        -1.067  -1.042  -0.969  -1.336  -1.281  -1.164  -1.101  -1.057  -0.948
6     I        -0.941  -0.945  -0.932  -0.980  -0.986  -0.965  -0.947  -0.945  -0.905
7     V        -1.067  -1.033  -0.969  -1.230  -1.162  -1.062  -1.101  -1.046  -0.948
8     P         1.286   1.305   1.337   1.420   1.447   1.499   1.361   1.384   1.426
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    T         1.286   1.305   1.337   1.333   1.359   1.415   1.361   1.384   1.426
12    Y         0.082  -0.020  -0.044   0.338   0.176   0.124  -0.024  -0.186  -0.231
13    G        -1.683  -1.644  -1.573  -1.862  -1.820  -1.672  -1.409  -1.352  -1.245
14    D         0.082  -0.020  -0.044   0.216   0.055   0.000  -0.024  -0.186  -0.231
15    V         1.286   1.305   1.337   1.275   1.313   1.359   1.361   1.384   1.426
16    L        -0.941  -0.877  -0.918  -1.201  -1.082  -1.166  -0.947  -0.857  -0.888
17    D        -1.683  -1.644  -1.573  -1.583  -1.562  -1.403  -1.409  -1.352  -1.245
18    A         1.286   1.305   1.337   1.051   1.079   1.143   1.361   1.384   1.426
19    S        -0.198  -0.163  -0.108  -0.184  -0.109  -0.023  -0.486  -0.424  -0.339
20    N        -1.683  -1.644  -1.573  -1.521  -1.459  -1.343  -1.409  -1.352  -1.245
21    R         0.082  -0.020  -0.044   0.181  -0.009  -0.071  -0.024  -0.186  -0.231
22    I         0.082   0.090  -0.019   0.039   0.058  -0.149  -0.024  -0.009  -0.190
23    K         0.082   0.090  -0.019   0.125   0.155  -0.028  -0.024  -0.009  -0.190
24    E        -0.941  -0.944  -0.936  -0.917  -0.906  -0.898  -0.947  -0.943  -0.909
25    Y        -0.941  -0.877  -0.918  -0.730  -0.625  -0.706  -0.947  -0.857  -0.888
26    V        -0.941  -0.944  -0.936  -1.212  -1.213  -1.174  -0.947  -0.943  -0.909
27    N        -0.941  -0.994  -0.947  -0.712  -0.787  -0.734  -0.947  -1.001  -0.923
28    K         0.082  -0.020  -0.044   0.097  -0.057  -0.114  -0.024  -0.186  -0.231
29    T         1.286   1.305   1.337   1.333   1.359   1.415   1.361   1.384   1.426
30    P         1.286   1.305   1.337   1.412   1.447   1.492   1.361   1.384   1.426
31    V         1.286   1.305   1.337   1.275   1.313   1.359   1.361   1.384   1.426
32    L         1.286   1.305   1.337   1.171   1.200   1.259   1.361   1.384   1.426
33    T         0.082   0.090  -0.019   0.139   0.149  -0.024  -0.024  -0.009  -0.190
34    S        -0.941  -0.994  -0.947  -0.838  -0.909  -0.840  -0.947  -1.001  -0.923
35    R        -1.683  -1.644  -1.573  -1.458  -1.409  -1.282  -1.409  -1.352  -1.245
36    M        -0.941  -0.876  -0.912  -0.890  -0.803  -0.839  -0.947  -0.855  -0.881
37    L        -1.683  -1.644  -1.573  -1.607  -1.503  -1.426  -1.409  -1.352  -1.245
38    N        -0.198  -0.163  -0.108  -0.178  -0.117  -0.034  -0.486  -0.424  -0.339
39    D        -1.067  -1.033  -0.969  -0.971  -0.888  -0.812  -1.101  -1.046  -0.948
40    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    L        -0.077  -0.023  -0.066  -0.223  -0.135  -0.190  -0.281  -0.190  -0.268
42    G        -1.067  -1.033  -0.969  -1.498  -1.460  -1.321  -1.101  -1.046  -0.948
43    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
45    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
46    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
47    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
48    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
49    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
50    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
57    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
58    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
59    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
60    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
61    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
62    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
63    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
64    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
65    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
66    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
67    A        -0.941  -0.994  -0.947  -1.185  -1.261  -1.155  -0.947  -1.001  -0.923
68    Q        -0.941  -0.945  -0.932  -0.757  -0.763  -0.753  -0.947  -0.945  -0.905
69    I        -1.683  -1.644  -1.573  -1.486  -1.391  -1.309  -1.409  -1.352  -1.245
70    Y        -0.941  -0.944  -0.936  -0.596  -0.587  -0.570  -0.947  -0.943  -0.909
71    F         0.082   0.090  -0.019   0.214   0.231   0.011  -0.024  -0.009  -0.190
72    K         1.286   1.305   1.337   1.302   1.346   1.385   1.361   1.384   1.426
73    G         0.082   0.181  -0.002   0.323   0.490   0.140  -0.024   0.131  -0.162
74    E         1.286   1.305   1.337   1.324   1.357   1.407   1.361   1.384   1.426
75    N         1.286   1.305   1.337   1.503   1.540   1.579   1.361   1.384   1.426
76    F         0.082   0.090  -0.019   0.252   0.272   0.066  -0.024  -0.009  -0.190
77    Q         1.286   1.305   1.337   1.477   1.514   1.554   1.361   1.384   1.426
78    R         0.082   0.179  -0.003   0.221   0.373   0.070  -0.024   0.128  -0.164
79    V        -1.683  -1.644  -1.573  -1.537  -1.487  -1.359  -1.409  -1.352  -1.245
80    G         1.286   1.305   1.337   1.121   1.146   1.210   1.361   1.384   1.426
81    A         1.286   1.305   1.337   1.051   1.079   1.143   1.361   1.384   1.426
82    F         1.286   1.305   1.337   1.473   1.508   1.550   1.361   1.384   1.426
83    K         1.286   1.305   1.337   1.302   1.346   1.385   1.361   1.384   1.426
84    F         0.082  -0.020  -0.044   0.178  -0.017  -0.098  -0.024  -0.186  -0.231
85    R         1.286   1.305   1.337   1.438   1.466   1.517   1.361   1.384   1.426
86    G         1.286   1.305   1.337   1.121   1.146   1.210   1.361   1.384   1.426
87    A         1.286   1.305   1.337   1.051   1.079   1.143   1.361   1.384   1.426
88    M        -1.683  -1.644  -1.573  -1.399  -1.322  -1.225  -1.409  -1.352  -1.245
89    N         0.082  -0.020  -0.044   0.358   0.211   0.164  -0.024  -0.186  -0.231
90    A         1.286   1.305   1.337   1.051   1.079   1.143   1.361   1.384   1.426
91    V        -0.198  -0.177  -0.116  -0.520  -0.477  -0.369  -0.486  -0.448  -0.352
92    S         0.082  -0.020  -0.044   0.157  -0.013  -0.060  -0.024  -0.186  -0.231
93    K        -0.941  -0.944  -0.936  -0.766  -0.765  -0.770  -0.947  -0.943  -0.909
94    L         0.082   0.090  -0.019   0.020   0.035  -0.112  -0.024  -0.009  -0.190
95    S        -0.941  -0.945  -0.932  -0.834  -0.855  -0.813  -0.947  -0.945  -0.905
96    D        -1.683  -1.644  -1.573  -1.476  -1.397  -1.300  -1.409  -1.352  -1.245
97    E        -1.683  -1.644  -1.573  -1.789  -1.702  -1.602  -1.409  -1.352  -1.245
98    K        -0.941  -0.944  -0.936  -0.814  -0.821  -0.826  -0.947  -0.943  -0.909
99    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
100   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
101   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
102   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
103   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
104   R        -0.198  -0.163  -0.108  -0.303  -0.246  -0.158  -0.486  -0.424  -0.339
105   S        -0.941  -0.876  -0.912  -1.055  -0.942  -1.016  -0.947  -0.855  -0.881
106   K        -0.941  -0.813  -0.909  -1.248  -1.030  -1.190  -0.947  -0.775  -0.877
107   G         1.286   1.305   1.337   1.121   1.146   1.210   1.361   1.384   1.426
108   V         1.286   1.305   1.337   1.275   1.313   1.359   1.361   1.384   1.426
109   I        -0.941  -0.944  -0.936  -1.105  -1.113  -1.083  -0.947  -0.943  -0.909
110   A         0.082   0.181  -0.002   0.040   0.201  -0.132  -0.024   0.131  -0.162
111   F        -0.941  -0.994  -0.947  -0.640  -0.710  -0.636  -0.947  -1.001  -0.923
112   S         1.286   1.305   1.337   1.364   1.393   1.445   1.361   1.384   1.426
113   S         1.286   1.305   1.337   1.364   1.393   1.445   1.361   1.384   1.426
114   G         1.286   1.305   1.337   1.121   1.146   1.210   1.361   1.384   1.426
115   N         1.286   1.305   1.337   1.503   1.540   1.579   1.361   1.384   1.426
116   H         1.286   1.305   1.337   1.542   1.574   1.617   1.361   1.384   1.426
117   A         1.286   1.305   1.337   1.051   1.079   1.143   1.361   1.384   1.426
118   Q         1.286   1.305   1.337   1.477   1.514   1.554   1.361   1.384   1.426
119   A         1.286   1.305   1.337   1.051   1.079   1.143   1.361   1.384   1.426
120   I         0.082  -0.020  -0.044   0.039  -0.137  -0.198  -0.024  -0.186  -0.231
121   A         0.082  -0.020  -0.044  -0.134  -0.292  -0.309  -0.024  -0.186  -0.231
122   L         0.082   0.090  -0.019   0.043   0.058  -0.078  -0.024  -0.009  -0.190
123   S        -0.198  -0.163  -0.108  -0.540  -0.510  -0.397  -0.486  -0.424  -0.339
124   A         1.286   1.305   1.337   1.051   1.079   1.143   1.361   1.384   1.426
125   K        -0.941  -0.994  -0.947  -1.021  -1.098  -1.044  -0.947  -1.001  -0.923
126   L        -1.683  -1.644  -1.573  -1.597  -1.516  -1.417  -1.409  -1.352  -1.245
127   L         0.082  -0.020  -0.044   0.030  -0.114  -0.133  -0.024  -0.186  -0.231
128   N         0.082   0.181  -0.002  -0.019   0.118  -0.116  -0.024   0.131  -0.162
129   V         0.082   0.181  -0.002   0.072   0.235  -0.069  -0.024   0.131  -0.162
130   P         0.082   0.090  -0.019   0.196   0.218   0.017  -0.024  -0.009  -0.190
131   A         1.286   1.305   1.337   1.051   1.079   1.143   1.361   1.384   1.426
132   T        -0.941  -0.945  -0.932  -0.843  -0.833  -0.816  -0.947  -0.945  -0.905
133   I         1.286   1.305   1.337   1.293   1.330   1.377   1.361   1.384   1.426
134   V        -0.198  -0.177  -0.116  -0.430  -0.386  -0.285  -0.486  -0.448  -0.352
135   M         1.286   1.305   1.337   1.559   1.594   1.633   1.361   1.384   1.426
136   P         1.286   1.305   1.337   1.412   1.447   1.492   1.361   1.384   1.426
137   E        -0.941  -0.813  -0.909  -0.994  -0.778  -0.948  -0.947  -0.775  -0.877
138   D         0.082  -0.020  -0.044   0.193   0.030  -0.034  -0.024  -0.186  -0.231
139   A         0.082  -0.020  -0.044  -0.134  -0.292  -0.309  -0.024  -0.186  -0.231
140   P         1.286   1.305   1.337   1.412   1.447   1.492   1.361   1.384   1.426
141   A        -1.683  -1.644  -1.573  -1.742  -1.638  -1.557  -1.409  -1.352  -1.245
142   L        -1.683  -1.644  -1.573  -1.795  -1.689  -1.608  -1.409  -1.352  -1.245
143   K         1.286   1.305   1.337   1.302   1.346   1.385   1.361   1.384   1.426
144   V        -0.941  -0.994  -0.947  -1.059  -1.148  -1.080  -0.947  -1.001  -0.923
145   A         0.082   0.090  -0.019  -0.095  -0.079  -0.214  -0.024  -0.009  -0.190
146   A         0.082   0.090  -0.019  -0.217  -0.208  -0.392  -0.024  -0.009  -0.190
147   T         1.286   1.305   1.337   1.333   1.359   1.415   1.361   1.384   1.426
148   A         0.082   0.181  -0.002   0.009   0.188  -0.160  -0.024   0.131  -0.162
149   G         0.082   0.090  -0.019  -0.050  -0.037  -0.186  -0.024  -0.009  -0.190
150   Y         0.082   0.090  -0.019   0.256   0.271   0.049  -0.024  -0.009  -0.190
151   G         1.286   1.305   1.337   1.121   1.146   1.210   1.361   1.384   1.426
152   A         0.082   0.179  -0.003  -0.217  -0.064  -0.362  -0.024   0.128  -0.164
153   H        -1.683  -1.644  -1.573  -1.332  -1.272  -1.161  -1.409  -1.352  -1.245
154   I         0.082   0.179  -0.003   0.072   0.232  -0.071  -0.024   0.128  -0.164
155   I        -0.941  -0.994  -0.947  -0.980  -1.066  -0.990  -0.947  -1.001  -0.923
156   R        -1.683  -1.644  -1.573  -1.319  -1.260  -1.148  -1.409  -1.352  -1.245
157   Y         0.082  -0.020  -0.044   0.315   0.146   0.088  -0.024  -0.186  -0.231
158   N        -0.941  -0.944  -0.936  -0.868  -0.909  -0.872  -0.947  -0.943  -0.909
159   R         0.082  -0.020  -0.044   0.241   0.069   0.023  -0.024  -0.186  -0.231
160   Y         0.082  -0.020  -0.044   0.305   0.133   0.074  -0.024  -0.186  -0.231
161   T        -0.941  -0.944  -0.936  -0.934  -0.935  -0.919  -0.947  -0.943  -0.909
162   E        -1.683  -1.644  -1.573  -1.492  -1.432  -1.316  -1.409  -1.352  -1.245
163   D         0.082  -0.020  -0.044   0.203   0.041  -0.019  -0.024  -0.186  -0.231
164   R         1.286   1.305   1.337   1.438   1.466   1.517   1.361   1.384   1.426
165   E         0.082   0.090  -0.019   0.147   0.166  -0.009  -0.024  -0.009  -0.190
166   Q        -1.683  -1.644  -1.573  -1.704  -1.679  -1.520  -1.409  -1.352  -1.245
167   I        -0.941  -0.813  -0.909  -0.888  -0.688  -0.821  -0.947  -0.775  -0.877
168   G        -0.941  -0.944  -0.936  -1.265  -1.264  -1.237  -0.947  -0.943  -0.909
169   R        -0.941  -0.877  -0.918  -0.772  -0.661  -0.737  -0.947  -0.857  -0.888
170   Q        -0.941  -0.876  -0.912  -0.984  -0.886  -0.942  -0.947  -0.855  -0.881
171   L        -0.941  -0.944  -0.936  -1.051  -1.053  -1.055  -0.947  -0.943  -0.909
172   A        -1.683  -1.644  -1.573  -1.867  -1.790  -1.678  -1.409  -1.352  -1.245
173   A        -0.941  -0.876  -0.912  -1.049  -0.928  -1.014  -0.947  -0.855  -0.881
174   E        -0.941  -0.945  -0.932  -0.896  -0.912  -0.874  -0.947  -0.945  -0.905
175   H        -0.941  -0.945  -0.932  -0.746  -0.769  -0.757  -0.947  -0.945  -0.905
176   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
177   G         0.082   0.090  -0.019  -0.080  -0.070  -0.229  -0.024  -0.009  -0.190
178   F        -1.683  -1.644  -1.573  -1.644  -1.613  -1.462  -1.409  -1.352  -1.245
179   A        -0.941  -0.944  -0.936  -0.994  -0.988  -0.999  -0.947  -0.943  -0.909
180   L         0.082   0.179  -0.003  -0.041   0.108  -0.172  -0.024   0.128  -0.164
181   I         0.082  -0.020  -0.044   0.072  -0.090  -0.146  -0.024  -0.186  -0.231
182   P         1.286   1.305   1.337   1.412   1.447   1.492   1.361   1.384   1.426
183   P         1.286   1.305   1.337   1.412   1.447   1.492   1.361   1.384   1.426
184   Y         1.286   1.305   1.337   1.516   1.549   1.592   1.361   1.384   1.426
185   D         1.286   1.305   1.337   1.412   1.451   1.492   1.361   1.384   1.426
186   H         1.286   1.305   1.337   1.542   1.574   1.617   1.361   1.384   1.426
187   P         1.286   1.305   1.337   1.412   1.447   1.492   1.361   1.384   1.426
188   D         0.082   0.179  -0.003   0.272   0.421   0.152  -0.024   0.128  -0.164
189   V        -0.198  -0.163  -0.108  -0.430  -0.356  -0.269  -0.486  -0.424  -0.339
190   I         0.082   0.179  -0.003   0.039   0.201  -0.118  -0.024   0.128  -0.164
191   A         0.082  -0.020  -0.044  -0.200  -0.378  -0.412  -0.024  -0.186  -0.231
192   G         1.286   1.305   1.337   1.121   1.146   1.210   1.361   1.384   1.426
193   Q         1.286   1.305   1.337   1.477   1.514   1.554   1.361   1.384   1.426
194   G         1.286   1.305   1.337   1.121   1.146   1.210   1.361   1.384   1.426
195   T         1.286   1.305   1.337   1.333   1.359   1.415   1.361   1.384   1.426
196   S        -0.941  -0.876  -0.912  -1.179  -1.084  -1.106  -0.947  -0.855  -0.881
197   A         0.082   0.090  -0.019  -0.164  -0.150  -0.315  -0.024  -0.009  -0.190
198   K         0.082  -0.020  -0.044   0.047  -0.123  -0.190  -0.024  -0.186  -0.231
199   E         1.286   1.305   1.337   1.324   1.357   1.407   1.361   1.384   1.426
200   L         1.286   1.305   1.337   1.171   1.200   1.259   1.361   1.384   1.426
201   L        -0.941  -0.945  -0.932  -0.934  -0.931  -0.879  -0.947  -0.945  -0.905
202   E         0.082  -0.020  -0.044   0.155  -0.001  -0.037  -0.024  -0.186  -0.231
203   E         0.082  -0.020  -0.044   0.168   0.019  -0.018  -0.024  -0.186  -0.231
204   V         0.082   0.090  -0.019   0.074   0.093  -0.089  -0.024  -0.009  -0.190
205   G         0.082  -0.020  -0.044  -0.171  -0.366  -0.413  -0.024  -0.186  -0.231
206   Q        -0.941  -0.944  -0.936  -0.907  -0.956  -0.919  -0.947  -0.943  -0.909
207   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
208   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
209   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
210   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
211   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
212   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
213   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
214   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
215   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
219   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
222   L         1.286   1.305   1.337   1.171   1.200   1.259   1.361   1.384   1.426
223   D         0.082  -0.020  -0.044   0.260   0.116   0.069  -0.024  -0.186  -0.231
224   A         0.082   0.090  -0.019  -0.117  -0.102  -0.247  -0.024  -0.009  -0.190
225   L        -0.198  -0.163  -0.108  -0.506  -0.428  -0.335  -0.486  -0.424  -0.339
226   F         0.082  -0.020  -0.044   0.252   0.083   0.018  -0.024  -0.186  -0.231
227   V         0.082  -0.020  -0.044   0.074  -0.087  -0.132  -0.024  -0.186  -0.231
228   P         0.082   0.179  -0.003   0.292   0.434   0.179  -0.024   0.128  -0.164
229   L         0.082  -0.020  -0.044   0.063  -0.073  -0.082  -0.024  -0.186  -0.231
230   G         1.286   1.305   1.337   1.121   1.146   1.210   1.361   1.384   1.426
231   G         1.286   1.305   1.337   1.121   1.146   1.210   1.361   1.384   1.426
232   G         1.286   1.305   1.337   1.121   1.146   1.210   1.361   1.384   1.426
233   G         1.286   1.305   1.337   1.121   1.146   1.210   1.361   1.384   1.426
234   L         1.286   1.305   1.337   1.171   1.200   1.259   1.361   1.384   1.426
235   L         1.286   1.305   1.337   1.171   1.200   1.259   1.361   1.384   1.426
236   S         0.082   0.090  -0.019   0.071   0.080  -0.140  -0.024  -0.009  -0.190
237   G         1.286   1.305   1.337   1.121   1.146   1.210   1.361   1.384   1.426
238   S         0.082  -0.020  -0.044   0.159  -0.013  -0.056  -0.024  -0.186  -0.231
239   A         0.082   0.090  -0.019  -0.200  -0.190  -0.367  -0.024  -0.009  -0.190
240   L         1.286   1.305   1.337   1.171   1.200   1.259   1.361   1.384   1.426
241   A         1.286   1.305   1.337   1.051   1.079   1.143   1.361   1.384   1.426
242   A         0.082  -0.020  -0.044  -0.051  -0.183  -0.182  -0.024  -0.186  -0.231
243   R        -0.941  -0.994  -0.947  -0.821  -0.921  -0.845  -0.947  -1.001  -0.923
244   S        -1.683  -1.644  -1.573  -1.453  -1.389  -1.278  -1.409  -1.352  -1.245
245   L         0.082   0.179  -0.003   0.020   0.159  -0.088  -0.024   0.128  -0.164
246   S        -0.198  -0.177  -0.116  -0.540  -0.496  -0.382  -0.486  -0.448  -0.352
247   P         1.286   1.305   1.337   1.412   1.447   1.492   1.361   1.384   1.426
248   G        -1.683  -1.644  -1.573  -1.629  -1.556  -1.447  -1.409  -1.352  -1.245
249   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
250   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
251   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
252   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
253   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
254   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
255   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
256   C         0.082  -0.020  -0.044   0.375   0.201   0.127  -0.024  -0.186  -0.231
257   K        -0.941  -0.945  -0.932  -1.021  -1.042  -1.015  -0.947  -0.945  -0.905
258   I         0.082   0.181  -0.002   0.061   0.222  -0.077  -0.024   0.131  -0.162
259   F        -0.941  -0.877  -0.918  -0.596  -0.498  -0.547  -0.947  -0.857  -0.888
260   G         1.286   1.305   1.337   1.121   1.146   1.210   1.361   1.384   1.426
261   V         0.082  -0.020  -0.044  -0.017  -0.204  -0.274  -0.024  -0.186  -0.231
262   E         1.286   1.305   1.337   1.324   1.357   1.407   1.361   1.384   1.426
263   P         1.286   1.305   1.337   1.412   1.447   1.492   1.361   1.384   1.426
264   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
265   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
266   E         0.082  -0.020  -0.044   0.131  -0.032  -0.075  -0.024  -0.186  -0.231
267   A        -0.941  -0.994  -0.947  -1.265  -1.372  -1.253  -0.947  -1.001  -0.923
268   G         0.082  -0.020  -0.044  -0.171  -0.366  -0.413  -0.024  -0.186  -0.231
269   N         0.082  -0.020  -0.044   0.318   0.161   0.101  -0.024  -0.186  -0.231
270   D         1.286   1.305   1.337   1.412   1.451   1.492   1.361   1.384   1.426
271   G         1.286   1.305   1.337   1.121   1.146   1.210   1.361   1.384   1.426
272   Q        -0.941  -0.994  -0.947  -0.766  -0.850  -0.791  -0.947  -1.001  -0.923
273   Q        -0.941  -0.994  -0.947  -0.819  -0.913  -0.856  -0.947  -1.001  -0.923
274   S         0.082  -0.020  -0.044   0.092  -0.100  -0.161  -0.024  -0.186  -0.231
275   F        -0.941  -0.994  -0.947  -0.790  -0.871  -0.819  -0.947  -1.001  -0.923
276   R        -0.941  -0.994  -0.947  -0.694  -0.770  -0.691  -0.947  -1.001  -0.923
277   S        -0.941  -0.877  -0.918  -0.862  -0.756  -0.823  -0.947  -0.857  -0.888
278   G         1.286   1.305   1.337   1.121   1.146   1.210   1.361   1.384   1.426
279   S        -0.941  -0.994  -0.947  -0.832  -0.926  -0.834  -0.947  -1.001  -0.923
280   I         0.082  -0.020  -0.044   0.125  -0.026  -0.064  -0.024  -0.186  -0.231
281   V         0.082  -0.020  -0.044   0.061  -0.100  -0.152  -0.024  -0.186  -0.231
282   H         0.082  -0.020  -0.044   0.327   0.155   0.091  -0.024  -0.186  -0.231
283   I         0.082  -0.020  -0.044   0.101  -0.057  -0.101  -0.024  -0.186  -0.231
284   N        -0.941  -0.944  -0.936  -0.804  -0.823  -0.797  -0.947  -0.943  -0.909
285   T         0.082  -0.020  -0.044   0.120  -0.049  -0.098  -0.024  -0.186  -0.231
286   P         0.082  -0.020  -0.044   0.216   0.052   0.000  -0.024  -0.186  -0.231
287   K        -0.941  -0.994  -0.947  -1.043  -1.143  -1.070  -0.947  -1.001  -0.923
288   T         1.286   1.305   1.337   1.333   1.359   1.415   1.361   1.384   1.426
289   I         1.286   1.305   1.337   1.293   1.330   1.377   1.361   1.384   1.426
290   A         1.286   1.305   1.337   1.051   1.079   1.143   1.361   1.384   1.426
291   D         1.286   1.305   1.337   1.412   1.451   1.492   1.361   1.384   1.426
292   G         1.286   1.305   1.337   1.121   1.146   1.210   1.361   1.384   1.426
293   A         0.082  -0.020  -0.044  -0.200  -0.378  -0.412  -0.024  -0.186  -0.231
294   Q         0.082  -0.020  -0.044   0.301   0.143   0.092  -0.024  -0.186  -0.231
295   T         1.286   1.305   1.337   1.333   1.359   1.415   1.361   1.384   1.426
296   Q         0.082  -0.020  -0.044   0.293   0.136   0.079  -0.024  -0.186  -0.231
297   H         1.286   1.305   1.337   1.537   1.568   1.612   1.361   1.384   1.426
298   L         1.286   1.305   1.337   1.171   1.200   1.259   1.361   1.384   1.426
299   G         1.286   1.305   1.337   1.121   1.146   1.210   1.361   1.384   1.426
300   E        -0.941  -0.945  -0.932  -0.972  -1.024  -0.964  -0.947  -0.945  -0.905
301   Y         0.082   0.090  -0.019   0.256   0.271   0.049  -0.024  -0.009  -0.190
302   T         0.082  -0.020  -0.044   0.155  -0.007  -0.043  -0.024  -0.186  -0.231
303   F         0.082  -0.020  -0.044   0.364   0.225   0.190  -0.024  -0.186  -0.231
304   A        -0.941  -0.876  -0.912  -0.978  -0.857  -0.943  -0.947  -0.855  -0.881
305   I         1.286   1.305   1.337   1.293   1.330   1.377   1.361   1.384   1.426
306   I         1.286   1.305   1.337   1.293   1.330   1.377   1.361   1.384   1.426
307   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
308   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
309   R        -0.941  -0.877  -0.918  -0.783  -0.672  -0.749  -0.947  -0.857  -0.888
310   E        -0.941  -0.994  -0.947  -0.896  -0.982  -0.898  -0.947  -1.001  -0.923
311   N        -0.941  -0.813  -0.909  -0.998  -0.806  -0.923  -0.947  -0.775  -0.877
312   V         1.286   1.305   1.337   1.275   1.313   1.359   1.361   1.384   1.426
313   D        -0.941  -0.994  -0.947  -0.970  -1.102  -1.020  -0.947  -1.001  -0.923
314   D         0.082  -0.020  -0.044   0.139  -0.045  -0.118  -0.024  -0.186  -0.231
315   I         0.082  -0.020  -0.044   0.165   0.029  -0.002  -0.024  -0.186  -0.231
316   L        -0.941  -0.994  -0.947  -0.992  -1.044  -0.962  -0.947  -1.001  -0.923
317   T         0.082  -0.020  -0.044   0.139  -0.030  -0.067  -0.024  -0.186  -0.231
318   V         1.286   1.305   1.337   1.275   1.313   1.359   1.361   1.384   1.426
319   S        -0.941  -0.994  -0.947  -0.909  -1.028  -0.928  -0.947  -1.001  -0.923
320   D        -0.198  -0.163  -0.108  -0.307  -0.247  -0.157  -0.486  -0.424  -0.339
321   Q        -0.941  -0.876  -0.912  -0.955  -0.858  -0.909  -0.947  -0.855  -0.881
322   E         1.286   1.305   1.337   1.324   1.357   1.407   1.361   1.384   1.426
323   L        -0.941  -0.994  -0.947  -0.976  -1.052  -0.944  -0.947  -1.001  -0.923
324   V        -0.941  -0.944  -0.936  -0.994  -0.991  -0.987  -0.947  -0.943  -0.909
325   K        -0.941  -0.877  -0.918  -1.033  -0.922  -1.004  -0.947  -0.857  -0.888
326   C        -0.941  -0.994  -0.947  -0.710  -0.847  -0.764  -0.947  -1.001  -0.923
327   M        -0.941  -0.876  -0.912  -0.959  -0.876  -0.885  -0.947  -0.855  -0.881
328   H        -1.683  -1.644  -1.573  -1.381  -1.314  -1.208  -1.409  -1.352  -1.245
329   F        -0.941  -0.994  -0.947  -0.734  -0.846  -0.750  -0.947  -1.001  -0.923
330   L        -0.941  -0.944  -0.936  -0.854  -0.868  -0.886  -0.947  -0.943  -0.909
331   A         0.082  -0.020  -0.044  -0.081  -0.222  -0.228  -0.024  -0.186  -0.231
332   E        -0.941  -0.877  -0.918  -1.001  -0.883  -0.973  -0.947  -0.857  -0.888
333   R         0.082   0.090  -0.019   0.221   0.236   0.040  -0.024  -0.009  -0.190
334   M         1.286   1.305   1.337   1.559   1.594   1.633   1.361   1.384   1.426
335   K         1.286   1.305   1.337   1.302   1.346   1.385   1.361   1.384   1.426
336   V        -0.941  -0.877  -0.918  -1.059  -0.948  -1.027  -0.947  -0.857  -0.888
337   V         1.286   1.305   1.337   1.275   1.313   1.359   1.361   1.384   1.426
338   V         1.286   1.305   1.337   1.275   1.313   1.359   1.361   1.384   1.426
339   E         1.286   1.305   1.337   1.324   1.357   1.407   1.361   1.384   1.426
340   P         1.286   1.305   1.337   1.412   1.447   1.492   1.361   1.384   1.426
341   T         0.082  -0.020  -0.044   0.139  -0.030  -0.067  -0.024  -0.186  -0.231
342   A        -0.198  -0.177  -0.116  -0.728  -0.703  -0.575  -0.486  -0.448  -0.352
343   C         0.082  -0.020  -0.044   0.369   0.194   0.119  -0.024  -0.186  -0.231
344   L        -0.941  -0.994  -0.947  -0.984  -1.061  -0.953  -0.947  -1.001  -0.923
345   G        -0.941  -0.877  -0.918  -1.218  -1.131  -1.174  -0.947  -0.857  -0.888
346   F        -0.198  -0.163  -0.108  -0.371  -0.336  -0.234  -0.486  -0.424  -0.339
347   A         1.286   1.305   1.337   1.051   1.079   1.143   1.361   1.384   1.426
348   G        -0.941  -0.944  -0.936  -1.293  -1.292  -1.270  -0.947  -0.943  -0.909
349   A         1.286   1.305   1.337   1.051   1.079   1.143   1.361   1.384   1.426
350   L        -0.941  -0.877  -0.918  -0.951  -0.862  -0.884  -0.947  -0.857  -0.888
351   L        -1.683  -1.644  -1.573  -1.758  -1.645  -1.572  -1.409  -1.352  -1.245
352   K        -1.683  -1.644  -1.573  -1.276  -1.196  -1.106  -1.409  -1.352  -1.245
353   K        -0.941  -0.994  -0.947  -0.834  -0.907  -0.815  -0.947  -1.001  -0.923
354   E         0.082   0.090  -0.019   0.053   0.067  -0.144  -0.024  -0.009  -0.190
355   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
356   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
357   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
358   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
359   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
360   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
361   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
362   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
363   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
364   E        -0.941  -0.813  -0.909  -1.123  -0.925  -1.052  -0.947  -0.775  -0.877
365   L        -0.941  -0.994  -0.947  -1.065  -1.149  -1.051  -0.947  -1.001  -0.923
366   V        -1.683  -1.644  -1.573  -1.547  -1.469  -1.368  -1.409  -1.352  -1.245
367   G        -0.941  -0.877  -0.918  -1.041  -0.953  -0.974  -0.947  -0.857  -0.888
368   K         0.082  -0.020  -0.044   0.203   0.079   0.050  -0.024  -0.186  -0.231
369   K        -0.941  -0.944  -0.936  -0.810  -0.811  -0.811  -0.947  -0.943  -0.909
370   V        -0.941  -0.945  -0.932  -1.059  -1.081  -1.052  -0.947  -0.945  -0.905
371   G         1.286   1.305   1.337   1.121   1.146   1.210   1.361   1.384   1.426
372   I        -0.198  -0.163  -0.108  -0.430  -0.359  -0.271  -0.486  -0.424  -0.339
373   I         0.082  -0.020  -0.044   0.072  -0.090  -0.146  -0.024  -0.186  -0.231
374   L        -0.941  -0.944  -0.936  -0.963  -0.944  -0.950  -0.947  -0.943  -0.909
375   S         1.286   1.305   1.337   1.364   1.393   1.445   1.361   1.384   1.426
376   G         1.286   1.305   1.337   1.121   1.146   1.210   1.361   1.384   1.426
377   G         1.286   1.305   1.337   1.121   1.146   1.210   1.361   1.384   1.426
378   N         1.286   1.305   1.337   1.503   1.540   1.579   1.361   1.384   1.426
379   V         1.286   1.305   1.337   1.275   1.313   1.359   1.361   1.384   1.426
380   D         0.082  -0.020  -0.044   0.203   0.041  -0.019  -0.024  -0.186  -0.231
381   M        -0.941  -0.813  -0.909  -0.976  -0.791  -0.900  -0.947  -0.775  -0.877
382   K        -1.683  -1.644  -1.573  -1.742  -1.703  -1.557  -1.409  -1.352  -1.245
383   R        -0.941  -0.994  -0.947  -0.961  -1.096  -1.018  -0.947  -1.001  -0.923
384   Y         0.082  -0.020  -0.044   0.256   0.070  -0.004  -0.024  -0.186  -0.231
385   A         0.082  -0.020  -0.044  -0.217  -0.402  -0.439  -0.024  -0.186  -0.231
386   T        -0.941  -0.945  -0.932  -0.786  -0.805  -0.750  -0.947  -0.945  -0.905
387   L        -0.941  -0.877  -0.918  -0.917  -0.827  -0.845  -0.947  -0.857  -0.888
388   I        -0.941  -0.944  -0.936  -1.015  -1.002  -0.978  -0.947  -0.943  -0.909
389   S        -0.941  -0.994  -0.947  -0.984  -1.113  -1.020  -0.947  -1.001  -0.923
390   G        -1.683  -1.644  -1.573  -1.649  -1.585  -1.467  -1.409  -1.352  -1.245
391   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
392   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
393   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
394   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
395   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
396   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
397   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
398   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
399   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P36007
Output conservation file - output/P36007
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
