1     M         0.948   0.959   1.012   1.145   1.153   1.221   0.995   1.009   1.084
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     S        -0.353  -0.349  -0.206  -0.626  -0.644  -0.409  -0.720  -0.718  -0.495
4     Q        -1.484  -1.471  -1.396  -1.478  -1.486  -1.365  -1.435  -1.415  -1.260
5     K        -0.872  -0.865  -0.876  -0.957  -0.903  -0.904  -1.006  -0.979  -0.969
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    K        -0.191  -0.148  -0.172  -0.325  -0.237  -0.296  -0.435  -0.363  -0.434
12    K         0.167   0.262  -0.098   0.185   0.329  -0.182   0.137   0.272  -0.305
13    A        -2.004  -2.014  -1.810  -1.894  -1.900  -1.643  -1.721  -1.708  -1.438
14    S        -0.965  -1.027  -0.897  -1.113  -1.176  -0.990  -1.149  -1.195  -0.996
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    H        -1.484  -1.495  -1.399  -1.321  -1.320  -1.174  -1.435  -1.432  -1.261
20    P        -1.484  -1.562  -1.411  -1.581  -1.711  -1.522  -1.435  -1.492  -1.272
21    A        -0.191  -0.083  -0.170  -0.470  -0.296  -0.446  -0.435  -0.255  -0.431
22    I        -0.872  -0.840  -0.879  -1.023  -1.002  -1.022  -1.006  -0.977  -0.975
23    N        -0.353  -0.330  -0.202  -0.324  -0.285  -0.103  -0.720  -0.682  -0.488
24    L         0.167   0.178  -0.105   0.164   0.182  -0.198   0.137   0.153  -0.318
25    M        -1.484  -1.433  -1.388  -1.518  -1.444  -1.348  -1.435  -1.366  -1.251
26    A         0.948   0.959   1.012   0.789   0.800   0.905   0.995   1.009   1.084
27    G         0.948   0.959   1.012   0.787   0.803   0.903   0.995   1.009   1.084
28    G         0.948   0.959   1.012   0.787   0.803   0.903   0.995   1.009   1.084
29    T        -0.872  -0.895  -0.878  -1.062  -1.127  -1.088  -1.006  -1.040  -0.974
30    A         0.948   0.959   1.012   0.789   0.800   0.905   0.995   1.009   1.084
31    G         0.948   0.959   1.012   0.787   0.803   0.903   0.995   1.009   1.084
32    L         0.167   0.019  -0.120   0.177  -0.009  -0.189   0.137  -0.089  -0.344
33    F        -0.191  -0.234  -0.192  -0.093  -0.167  -0.123  -0.435  -0.511  -0.471
34    E         0.948   0.959   1.012   1.009   1.028   1.100   0.995   1.009   1.084
35    A         0.167   0.236  -0.102   0.065   0.153  -0.351   0.137   0.236  -0.311
36    L         0.948   0.959   1.012   0.839   0.855   0.949   0.995   1.009   1.084
37    C        -0.191  -0.274  -0.197  -0.048  -0.231  -0.177  -0.435  -0.583  -0.479
38    C         0.948   0.959   1.012   1.230   1.244   1.297   0.995   1.009   1.084
39    H         0.948   0.959   1.012   1.182   1.193   1.254   0.995   1.009   1.084
40    P         0.948   0.959   1.012   1.025   1.055   1.115   0.995   1.009   1.084
41    L         0.948   0.959   1.012   0.839   0.855   0.949   0.995   1.009   1.084
42    D         0.948   0.959   1.012   1.180   1.194   1.252   0.995   1.009   1.084
43    T         0.948   0.959   1.012   0.888   0.900   0.993   0.995   1.009   1.084
44    I         0.948   0.959   1.012   0.932   0.950   1.032   0.995   1.009   1.084
45    K         0.948   0.959   1.012   0.868   0.908   0.975   0.995   1.009   1.084
46    V         0.948   0.959   1.012   0.861   0.872   0.969   0.995   1.009   1.084
47    R         0.948   0.959   1.012   1.028   1.034   1.117   0.995   1.009   1.084
48    M         0.948   0.959   1.012   1.145   1.153   1.221   0.995   1.009   1.084
49    Q         0.948   0.959   1.012   1.037   1.044   1.125   0.995   1.009   1.084
50    I        -0.353  -0.289  -0.190  -0.684  -0.569  -0.405  -0.720  -0.609  -0.466
51    Y        -0.569  -0.741  -0.860  -0.309  -0.561  -0.796  -0.577  -0.804  -0.947
52    R        -0.872  -0.836  -0.873  -0.913  -0.821  -0.869  -1.006  -0.937  -0.967
53    R        -0.872  -0.777  -0.861  -0.841  -0.692  -0.813  -1.006  -0.878  -0.950
54    V        -2.004  -1.976  -1.801  -1.978  -1.962  -1.727  -1.721  -1.681  -1.431
55    A        -1.589  -1.607  -1.419  -1.672  -1.672  -1.365  -1.526  -1.535  -1.280
56    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
57    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
58    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
59    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
60    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
61    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
62    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
63    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
64    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
65    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
66    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
67    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
68    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
69    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
70    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
71    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
72    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
73    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
74    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
75    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
76    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
77    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
78    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
79    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
80    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
81    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
82    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
83    I        -1.693  -1.602  -1.424  -1.957  -1.805  -1.532  -1.632  -1.527  -1.285
84    E        -1.693  -1.602  -1.424  -1.781  -1.593  -1.375  -1.632  -1.527  -1.285
85    H        -0.569  -0.415  -0.827  -0.574  -0.373  -0.921  -0.577  -0.377  -0.905
86    V        -0.965  -0.882  -0.886  -1.090  -0.981  -0.941  -1.149  -1.054  -0.985
87    K         0.167   0.019  -0.120   0.146  -0.045  -0.320   0.137  -0.089  -0.344
88    P        -1.250  -1.347  -1.384  -1.056  -1.198  -1.343  -1.149  -1.258  -1.246
89    P        -0.569  -0.741  -0.860  -0.355  -0.593  -0.834  -0.577  -0.804  -0.947
90    G         0.948   0.959   1.012   0.787   0.803   0.903   0.995   1.009   1.084
91    F         0.948   0.959   1.012   1.073   1.086   1.157   0.995   1.009   1.084
92    I         0.167   0.125  -0.112   0.221   0.167  -0.222   0.137   0.074  -0.330
93    K        -0.872  -0.926  -0.886  -0.926  -0.987  -0.906  -1.006  -1.070  -0.984
94    T         0.948   0.959   1.012   0.888   0.900   0.993   0.995   1.009   1.084
95    G         0.948   0.959   1.012   0.787   0.803   0.903   0.995   1.009   1.084
96    R        -1.484  -1.324  -1.383  -1.559  -1.328  -1.411  -1.435  -1.250  -1.246
97    T        -0.872  -0.847  -0.881  -0.765  -0.747  -0.822  -1.006  -0.988  -0.977
98    I         0.948   0.959   1.012   0.932   0.950   1.032   0.995   1.009   1.084
99    Y        -0.965  -0.964  -0.891  -1.099  -1.111  -0.996  -1.149  -1.127  -0.989
100   Q        -1.484  -1.405  -1.398  -1.471  -1.388  -1.367  -1.435  -1.361  -1.261
101   K        -0.569  -0.422  -0.824  -0.462  -0.252  -0.794  -0.577  -0.386  -0.901
102   E         0.948   0.959   1.012   1.009   1.028   1.100   0.995   1.009   1.084
103   G        -0.191  -0.224  -0.191  -0.462  -0.524  -0.470  -0.435  -0.494  -0.468
104   F        -0.569  -0.741  -0.860  -0.323  -0.587  -0.830  -0.577  -0.804  -0.947
105   L         0.167   0.262  -0.098   0.177   0.291  -0.156   0.137   0.272  -0.305
106   A        -0.872  -0.943  -0.883  -1.064  -1.173  -1.073  -1.006  -1.075  -0.978
107   L         0.167   0.236  -0.102   0.164   0.251  -0.192   0.137   0.236  -0.311
108   Y         0.948   0.959   1.012   1.070   1.082   1.155   0.995   1.009   1.084
109   K         0.948   0.959   1.012   0.868   0.908   0.975   0.995   1.009   1.084
110   G         0.948   0.959   1.012   0.787   0.803   0.903   0.995   1.009   1.084
111   L         0.948   0.959   1.012   0.839   0.855   0.949   0.995   1.009   1.084
112   G         0.948   0.959   1.012   0.787   0.803   0.903   0.995   1.009   1.084
113   A         0.948   0.959   1.012   0.789   0.800   0.905   0.995   1.009   1.084
114   V         0.948   0.959   1.012   0.861   0.872   0.969   0.995   1.009   1.084
115   V         0.167   0.019  -0.120   0.146  -0.068  -0.305   0.137  -0.089  -0.344
116   I        -0.191  -0.274  -0.197  -0.322  -0.482  -0.376  -0.435  -0.583  -0.479
117   G         0.948   0.959   1.012   0.787   0.803   0.903   0.995   1.009   1.084
118   I         0.948   0.959   1.012   0.932   0.950   1.032   0.995   1.009   1.084
119   I        -0.872  -0.743  -0.868  -1.013  -0.812  -0.998  -1.006  -0.827  -0.959
120   P         0.948   0.959   1.012   1.025   1.055   1.115   0.995   1.009   1.084
121   K         0.948   0.959   1.012   0.868   0.908   0.975   0.995   1.009   1.084
122   M         0.948   0.959   1.012   1.145   1.153   1.221   0.995   1.009   1.084
123   A         0.948   0.959   1.012   0.789   0.800   0.905   0.995   1.009   1.084
124   I         0.167   0.262  -0.098   0.217   0.344  -0.204   0.137   0.272  -0.305
125   R         0.948   0.959   1.012   1.028   1.034   1.117   0.995   1.009   1.084
126   F         0.948   0.959   1.012   1.073   1.086   1.157   0.995   1.009   1.084
127   S        -0.191  -0.274  -0.197  -0.244  -0.404  -0.317  -0.435  -0.583  -0.479
128   S         0.948   0.959   1.012   1.014   1.036   1.104   0.995   1.009   1.084
129   Y         0.167   0.019  -0.120   0.394   0.195  -0.037   0.137  -0.089  -0.344
130   E         0.948   0.959   1.012   1.009   1.028   1.100   0.995   1.009   1.084
131   F        -0.569  -0.741  -0.860  -0.225  -0.448  -0.623  -0.577  -0.804  -0.947
132   Y         0.948   0.959   1.012   1.070   1.082   1.155   0.995   1.009   1.084
133   R         0.167   0.019  -0.120   0.318   0.106  -0.156   0.137  -0.089  -0.344
134   T        -1.484  -1.562  -1.411  -1.514  -1.618  -1.394  -1.435  -1.492  -1.272
135   L         0.167   0.178  -0.105   0.164   0.182  -0.198   0.137   0.153  -0.318
136   L         0.167   0.178  -0.105   0.164   0.182  -0.198   0.137   0.153  -0.318
137   V        -1.862  -1.781  -1.785  -1.894  -1.792  -1.777  -1.578  -1.490  -1.418
138   N        -0.123  -0.038  -0.165   0.112   0.241  -0.012  -0.318  -0.181  -0.422
139   K        -0.569  -0.481  -0.833  -0.446  -0.310  -0.775  -0.577  -0.462  -0.913
140   E        -1.107  -1.095  -0.917  -1.147  -1.123  -0.863  -1.292  -1.270  -1.019
141   S        -1.484  -1.417  -1.393  -1.343  -1.252  -1.170  -1.435  -1.355  -1.256
142   G         0.948   0.959   1.012   0.787   0.803   0.903   0.995   1.009   1.084
143   I        -2.004  -1.930  -1.794  -2.068  -1.956  -1.731  -1.721  -1.643  -1.426
144   V        -0.353  -0.330  -0.202  -0.666  -0.629  -0.410  -0.720  -0.682  -0.488
145   S         0.948   0.959   1.012   1.014   1.036   1.104   0.995   1.009   1.084
146   T        -0.569  -0.741  -0.860  -0.554  -0.830  -1.072  -0.577  -0.804  -0.947
147   G        -1.250  -1.324  -1.382  -1.176  -1.282  -1.307  -1.149  -1.234  -1.244
148   N        -1.250  -1.388  -1.388  -0.948  -1.172  -1.230  -1.149  -1.300  -1.250
149   T         0.948   0.959   1.012   0.888   0.900   0.993   0.995   1.009   1.084
150   F         0.948   0.959   1.012   1.073   1.086   1.157   0.995   1.009   1.084
151   V        -1.484  -1.495  -1.399  -1.545  -1.539  -1.393  -1.435  -1.432  -1.261
152   A         0.948   0.959   1.012   0.789   0.800   0.905   0.995   1.009   1.084
153   G         0.948   0.959   1.012   0.787   0.803   0.903   0.995   1.009   1.084
154   V         0.167   0.019  -0.120   0.146  -0.068  -0.305   0.137  -0.089  -0.344
155   G         0.167   0.019  -0.120   0.063  -0.150  -0.388   0.137  -0.089  -0.344
156   A         0.948   0.959   1.012   0.789   0.800   0.905   0.995   1.009   1.084
157   G         0.948   0.959   1.012   0.787   0.803   0.903   0.995   1.009   1.084
158   I        -0.872  -0.926  -0.886  -0.980  -1.076  -1.022  -1.006  -1.070  -0.984
159   T         0.948   0.959   1.012   0.888   0.900   0.993   0.995   1.009   1.084
160   E         0.948   0.959   1.012   1.009   1.028   1.100   0.995   1.009   1.084
161   A         0.167   0.178  -0.105   0.104   0.118  -0.263   0.137   0.153  -0.318
162   V         0.948   0.959   1.012   0.861   0.872   0.969   0.995   1.009   1.084
163   L        -1.484  -1.500  -1.396  -1.528  -1.575  -1.410  -1.435  -1.436  -1.258
164   V         0.948   0.959   1.012   0.861   0.872   0.969   0.995   1.009   1.084
165   V         0.948   0.959   1.012   0.861   0.872   0.969   0.995   1.009   1.084
166   N         0.167   0.019  -0.120   0.387   0.180  -0.095   0.137  -0.089  -0.344
167   P         0.948   0.959   1.012   1.025   1.055   1.115   0.995   1.009   1.084
168   M         0.167   0.125  -0.112   0.438   0.374  -0.037   0.137   0.074  -0.330
169   E         0.948   0.959   1.012   1.009   1.028   1.100   0.995   1.009   1.084
170   V         0.948   0.959   1.012   0.861   0.872   0.969   0.995   1.009   1.084
171   V        -0.191  -0.274  -0.197  -0.373  -0.527  -0.401  -0.435  -0.583  -0.479
172   K         0.948   0.959   1.012   0.868   0.908   0.975   0.995   1.009   1.084
173   I         0.948   0.959   1.012   0.932   0.950   1.032   0.995   1.009   1.084
174   R         0.948   0.959   1.012   1.028   1.034   1.117   0.995   1.009   1.084
175   L         0.948   0.959   1.012   0.839   0.855   0.949   0.995   1.009   1.084
176   Q         0.948   0.959   1.012   1.037   1.044   1.125   0.995   1.009   1.084
177   A         0.948   0.959   1.012   0.789   0.800   0.905   0.995   1.009   1.084
178   Q         0.948   0.959   1.012   1.037   1.044   1.125   0.995   1.009   1.084
179   H         0.948   0.959   1.012   1.182   1.193   1.254   0.995   1.009   1.084
180   L        -0.353  -0.289  -0.190  -0.454  -0.318  -0.203  -0.720  -0.609  -0.466
181   T        -0.872  -0.741  -0.868  -0.799  -0.593  -0.811  -1.006  -0.825  -0.959
182   P        -0.353  -0.289  -0.190  -0.375  -0.253  -0.131  -0.720  -0.609  -0.466
183   S        -1.862  -1.704  -1.775  -1.835  -1.611  -1.689  -1.578  -1.413  -1.410
184   E        -0.872  -0.732  -0.870  -0.625  -0.419  -0.628  -1.006  -0.820  -0.961
185   P         0.090   0.154  -0.114   0.264   0.364  -0.025   0.022   0.117  -0.333
186   N         0.090   0.151  -0.117   0.063   0.145  -0.211   0.022   0.112  -0.339
187   A        -0.872  -0.743  -0.868  -0.804  -0.576  -0.875  -1.006  -0.827  -0.959
188   G        -1.862  -1.704  -1.775  -1.918  -1.660  -1.839  -1.578  -1.413  -1.410
189   P         0.948   0.959   1.012   1.025   1.055   1.115   0.995   1.009   1.084
190   K         0.948   0.959   1.012   0.868   0.908   0.975   0.995   1.009   1.084
191   Y         0.948   0.959   1.012   1.070   1.082   1.155   0.995   1.009   1.084
192   N        -1.250  -1.065  -1.364  -1.010  -0.753  -1.229  -1.149  -0.932  -1.225
193   N         0.948   0.959   1.012   1.094   1.111   1.176   0.995   1.009   1.084
194   A         0.948   0.959   1.012   0.789   0.800   0.905   0.995   1.009   1.084
195   I        -1.627  -1.546  -1.413  -1.811  -1.705  -1.469  -1.578  -1.487  -1.275
196   H        -0.191  -0.098  -0.154  -0.031   0.115  -0.026  -0.435  -0.279  -0.403
197   A         0.167   0.125  -0.112   0.143   0.093  -0.179   0.137   0.074  -0.330
198   A        -1.484  -1.405  -1.398  -1.641  -1.558  -1.446  -1.435  -1.361  -1.261
199   Y         0.948   0.959   1.012   1.070   1.082   1.155   0.995   1.009   1.084
200   T        -0.191  -0.135  -0.163  -0.383  -0.290  -0.366  -0.435  -0.341  -0.419
201   I        -0.191  -0.274  -0.197  -0.333  -0.496  -0.392  -0.435  -0.583  -0.479
202   V         0.167   0.268  -0.099   0.162   0.286  -0.228   0.137   0.281  -0.307
203   K         0.167   0.125  -0.112   0.186   0.156  -0.204   0.137   0.074  -0.330
204   E         0.948   0.959   1.012   1.009   1.028   1.100   0.995   1.009   1.084
205   E         0.948   0.959   1.012   1.009   1.028   1.100   0.995   1.009   1.084
206   G         0.948   0.959   1.012   0.787   0.803   0.903   0.995   1.009   1.084
207   V        -1.250  -1.155  -1.364  -0.975  -0.836  -1.213  -1.149  -1.038  -1.226
208   S         0.167   0.019  -0.120   0.291   0.083  -0.202   0.137  -0.089  -0.344
209   A        -0.191  -0.135  -0.163  -0.459  -0.371  -0.419  -0.435  -0.341  -0.419
210   L         0.948   0.959   1.012   0.839   0.855   0.949   0.995   1.009   1.084
211   Y         0.948   0.959   1.012   1.070   1.082   1.155   0.995   1.009   1.084
212   R         0.948   0.959   1.012   1.028   1.034   1.117   0.995   1.009   1.084
213   G         0.948   0.959   1.012   0.787   0.803   0.903   0.995   1.009   1.084
214   V         0.948   0.959   1.012   0.861   0.872   0.969   0.995   1.009   1.084
215   S         0.167   0.125  -0.112   0.314   0.268  -0.126   0.137   0.074  -0.330
216   L         0.948   0.959   1.012   0.839   0.855   0.949   0.995   1.009   1.084
217   T         0.948   0.959   1.012   0.888   0.900   0.993   0.995   1.009   1.084
218   A         0.167   0.178  -0.105   0.143   0.156  -0.170   0.137   0.153  -0.318
219   A        -0.569  -0.741  -0.860  -0.624  -0.889  -1.080  -0.577  -0.804  -0.947
220   R         0.948   0.959   1.012   1.028   1.034   1.117   0.995   1.009   1.084
221   Q         0.948   0.959   1.012   1.037   1.044   1.125   0.995   1.009   1.084
222   A         0.167   0.019  -0.120   0.065  -0.152  -0.387   0.137  -0.089  -0.344
223   T         0.167   0.019  -0.120   0.203   0.005  -0.207   0.137  -0.089  -0.344
224   N         0.948   0.959   1.012   1.094   1.111   1.176   0.995   1.009   1.084
225   Q         0.948   0.959   1.012   1.037   1.044   1.125   0.995   1.009   1.084
226   G         0.167   0.019  -0.120   0.063  -0.150  -0.388   0.137  -0.089  -0.344
227   A        -0.353  -0.348  -0.206  -0.771  -0.773  -0.508  -0.720  -0.716  -0.495
228   N         0.948   0.959   1.012   1.094   1.111   1.176   0.995   1.009   1.084
229   F         0.948   0.959   1.012   1.073   1.086   1.157   0.995   1.009   1.084
230   T         0.167   0.178  -0.105   0.165   0.178  -0.275   0.137   0.153  -0.318
231   V        -0.569  -0.696  -0.848  -0.561  -0.768  -1.027  -0.577  -0.747  -0.933
232   Y         0.948   0.959   1.012   1.070   1.082   1.155   0.995   1.009   1.084
233   S         0.948   0.959   1.012   1.014   1.036   1.104   0.995   1.009   1.084
234   K        -1.250  -1.388  -1.388  -1.136  -1.308  -1.326  -1.149  -1.300  -1.250
235   L        -0.872  -0.943  -0.883  -0.989  -1.065  -0.958  -1.006  -1.075  -0.978
236   K         0.167   0.268  -0.099   0.186   0.334  -0.182   0.137   0.281  -0.307
237   E        -0.872  -0.988  -0.891  -0.945  -1.134  -1.026  -1.006  -1.138  -0.989
238   F        -1.484  -1.562  -1.411  -1.211  -1.293  -1.078  -1.435  -1.492  -1.272
239   L         0.948   0.959   1.012   0.839   0.855   0.949   0.995   1.009   1.084
240   Q        -0.569  -0.741  -0.860  -0.290  -0.533  -0.712  -0.577  -0.804  -0.947
241   N        -2.004  -1.996  -1.797  -1.910  -1.848  -1.568  -1.721  -1.695  -1.428
242   Y        -0.569  -0.604  -0.840  -0.255  -0.304  -0.651  -0.577  -0.621  -0.922
243   H        -0.353  -0.349  -0.205  -0.338  -0.362  -0.142  -0.720  -0.718  -0.494
244   Q        -1.484  -1.401  -1.397  -1.337  -1.229  -1.245  -1.435  -1.357  -1.260
245   M        -1.484  -1.511  -1.398  -1.409  -1.453  -1.229  -1.435  -1.451  -1.261
246   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
247   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
248   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
249   D        -1.250  -1.341  -1.385  -0.990  -1.142  -1.214  -1.149  -1.252  -1.247
250   V        -1.862  -1.842  -1.782  -1.727  -1.702  -1.597  -1.578  -1.554  -1.415
251   L         0.948   0.959   1.012   0.839   0.855   0.949   0.995   1.009   1.084
252   P         0.948   0.959   1.012   1.025   1.055   1.115   0.995   1.009   1.084
253   S        -0.191  -0.135  -0.163  -0.281  -0.176  -0.292  -0.435  -0.341  -0.419
254   W         0.167   0.019  -0.120   0.572   0.369   0.104   0.137  -0.089  -0.344
255   E        -0.353  -0.349  -0.205  -0.479  -0.480  -0.248  -0.720  -0.718  -0.494
256   T         0.948   0.959   1.012   0.888   0.900   0.993   0.995   1.009   1.084
257   S         0.167   0.019  -0.120   0.307   0.106  -0.160   0.137  -0.089  -0.344
258   C        -1.107  -1.110  -0.918  -1.121  -1.166  -0.890  -1.292  -1.288  -1.021
259   I         0.167   0.178  -0.105   0.221   0.240  -0.209   0.137   0.153  -0.318
260   G         0.948   0.959   1.012   0.787   0.803   0.903   0.995   1.009   1.084
261   L         0.948   0.959   1.012   0.839   0.855   0.949   0.995   1.009   1.084
262   I         0.167   0.019  -0.120   0.221   0.014  -0.237   0.137  -0.089  -0.344
263   S         0.948   0.959   1.012   1.014   1.036   1.104   0.995   1.009   1.084
264   G         0.948   0.959   1.012   0.787   0.803   0.903   0.995   1.009   1.084
265   A         0.948   0.959   1.012   0.789   0.800   0.905   0.995   1.009   1.084
266   I        -1.484  -1.544  -1.406  -1.524  -1.589  -1.379  -1.435  -1.478  -1.269
267   G         0.948   0.959   1.012   0.787   0.803   0.903   0.995   1.009   1.084
268   P         0.948   0.959   1.012   1.025   1.055   1.115   0.995   1.009   1.084
269   F        -0.353  -0.289  -0.190  -0.594  -0.495  -0.324  -0.720  -0.609  -0.466
270   S         0.167   0.178  -0.105   0.307   0.330  -0.131   0.137   0.153  -0.318
271   N         0.948   0.959   1.012   1.094   1.111   1.176   0.995   1.009   1.084
272   A         0.948   0.959   1.012   0.789   0.800   0.905   0.995   1.009   1.084
273   P         0.948   0.959   1.012   1.025   1.055   1.115   0.995   1.009   1.084
274   L        -0.191  -0.274  -0.197  -0.395  -0.542  -0.417  -0.435  -0.583  -0.479
275   D         0.948   0.959   1.012   1.180   1.194   1.252   0.995   1.009   1.084
276   T         0.948   0.959   1.012   0.888   0.900   0.993   0.995   1.009   1.084
277   I         0.948   0.959   1.012   0.932   0.950   1.032   0.995   1.009   1.084
278   K         0.948   0.959   1.012   0.868   0.908   0.975   0.995   1.009   1.084
279   T         0.948   0.959   1.012   0.888   0.900   0.993   0.995   1.009   1.084
280   R         0.948   0.959   1.012   1.028   1.034   1.117   0.995   1.009   1.084
281   L         0.167   0.125  -0.112   0.177   0.128  -0.177   0.137   0.074  -0.330
282   Q         0.948   0.959   1.012   1.037   1.044   1.125   0.995   1.009   1.084
283   K         0.167   0.125  -0.112   0.186   0.156  -0.204   0.137   0.074  -0.330
284   D        -1.484  -1.467  -1.402  -1.255  -1.250  -1.190  -1.435  -1.415  -1.265
285   K        -1.250  -1.328  -1.384  -1.243  -1.368  -1.510  -1.149  -1.239  -1.246
286   S        -1.862  -1.908  -1.804  -1.662  -1.784  -1.638  -1.578  -1.613  -1.433
287   I        -1.484  -1.507  -1.399  -1.601  -1.634  -1.439  -1.435  -1.446  -1.262
288   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
289   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
290   E        -2.381  -2.360  -2.133  -2.119  -2.054  -1.740  -1.864  -1.830  -1.545
291   K        -1.107  -1.087  -0.915  -1.286  -1.254  -1.021  -1.292  -1.259  -1.017
292   Q        -0.569  -0.445  -0.827  -0.314  -0.155  -0.676  -0.577  -0.414  -0.906
293   S        -0.569  -0.696  -0.848  -0.349  -0.533  -0.784  -0.577  -0.747  -0.933
294   G         0.167   0.019  -0.120   0.063  -0.150  -0.388   0.137  -0.089  -0.344
295   M        -1.250  -1.236  -1.373  -1.039  -1.041  -1.125  -1.149  -1.138  -1.235
296   K        -1.484  -1.562  -1.411  -1.554  -1.626  -1.387  -1.435  -1.492  -1.272
297   K         0.167   0.243  -0.105   0.318   0.413  -0.126   0.137   0.247  -0.317
298   I         0.167   0.125  -0.112   0.257   0.209  -0.134   0.137   0.074  -0.330
299   I        -1.484  -1.340  -1.385  -1.633  -1.411  -1.479  -1.435  -1.274  -1.248
300   T        -1.862  -1.739  -1.785  -1.700  -1.515  -1.571  -1.578  -1.450  -1.418
301   I         0.948   0.959   1.012   0.932   0.950   1.032   0.995   1.009   1.084
302   G        -1.250  -1.328  -1.384  -1.286  -1.401  -1.497  -1.149  -1.239  -1.246
303   A        -2.004  -1.918  -1.793  -2.054  -1.934  -1.698  -1.721  -1.634  -1.425
304   Q         0.167   0.019  -0.120   0.350   0.144  -0.090   0.137  -0.089  -0.344
305   L         0.167   0.019  -0.120   0.177  -0.009  -0.189   0.137  -0.089  -0.344
306   L        -1.484  -1.516  -1.394  -1.545  -1.559  -1.386  -1.435  -1.445  -1.257
307   K        -0.569  -0.553  -0.835  -0.444  -0.397  -0.774  -0.577  -0.556  -0.916
308   E        -0.191  -0.274  -0.197  -0.193  -0.340  -0.235  -0.435  -0.583  -0.479
309   E         0.948   0.959   1.012   1.009   1.028   1.100   0.995   1.009   1.084
310   G         0.948   0.959   1.012   0.787   0.803   0.903   0.995   1.009   1.084
311   F        -0.191  -0.135  -0.163  -0.172  -0.078  -0.178  -0.435  -0.341  -0.419
312   R        -0.872  -0.889  -0.885  -0.701  -0.734  -0.700  -1.006  -1.030  -0.983
313   A         0.948   0.959   1.012   0.789   0.800   0.905   0.995   1.009   1.084
314   L         0.167   0.019  -0.120   0.164  -0.027  -0.221   0.137  -0.089  -0.344
315   Y         0.948   0.959   1.012   1.070   1.082   1.155   0.995   1.009   1.084
316   K         0.948   0.959   1.012   0.868   0.908   0.975   0.995   1.009   1.084
317   G         0.948   0.959   1.012   0.787   0.803   0.903   0.995   1.009   1.084
318   I         0.948   0.959   1.012   0.932   0.950   1.032   0.995   1.009   1.084
319   T         0.948   0.959   1.012   0.888   0.900   0.993   0.995   1.009   1.084
320   P         0.948   0.959   1.012   1.025   1.055   1.115   0.995   1.009   1.084
321   R         0.948   0.959   1.012   1.028   1.034   1.117   0.995   1.009   1.084
322   V        -0.353  -0.289  -0.190  -0.651  -0.526  -0.376  -0.720  -0.609  -0.466
323   M         0.948   0.959   1.012   1.145   1.153   1.221   0.995   1.009   1.084
324   R         0.948   0.959   1.012   1.028   1.034   1.117   0.995   1.009   1.084
325   V         0.948   0.959   1.012   0.861   0.872   0.969   0.995   1.009   1.084
326   A         0.948   0.959   1.012   0.789   0.800   0.905   0.995   1.009   1.084
327   P         0.948   0.959   1.012   1.025   1.055   1.115   0.995   1.009   1.084
328   G         0.948   0.959   1.012   0.787   0.803   0.903   0.995   1.009   1.084
329   Q         0.948   0.959   1.012   1.037   1.044   1.125   0.995   1.009   1.084
330   A         0.948   0.959   1.012   0.789   0.800   0.905   0.995   1.009   1.084
331   V         0.948   0.959   1.012   0.861   0.872   0.969   0.995   1.009   1.084
332   T         0.167   0.178  -0.105   0.177   0.190  -0.245   0.137   0.153  -0.318
333   F         0.948   0.959   1.012   1.073   1.086   1.157   0.995   1.009   1.084
334   T         0.948   0.959   1.012   0.888   0.900   0.993   0.995   1.009   1.084
335   V         0.167   0.236  -0.102   0.138   0.225  -0.290   0.137   0.236  -0.311
336   Y         0.948   0.959   1.012   1.070   1.082   1.155   0.995   1.009   1.084
337   E         0.948   0.959   1.012   1.009   1.028   1.100   0.995   1.009   1.084
338   Y        -0.965  -0.939  -0.884  -0.948  -0.912  -0.844  -1.149  -1.108  -0.982
339   V        -1.484  -1.512  -1.399  -1.476  -1.532  -1.339  -1.435  -1.450  -1.262
340   R        -0.353  -0.345  -0.206  -0.566  -0.557  -0.343  -0.720  -0.710  -0.494
341   E        -2.381  -2.369  -2.126  -2.105  -2.098  -1.765  -1.864  -1.835  -1.541
342   H        -2.004  -1.998  -1.803  -1.810  -1.826  -1.537  -1.721  -1.696  -1.433
343   L         0.948   0.959   1.012   0.839   0.855   0.949   0.995   1.009   1.084
344   E        -0.569  -0.481  -0.833  -0.413  -0.287  -0.883  -0.577  -0.462  -0.913
345   N        -1.250  -1.246  -1.368  -0.985  -0.980  -1.257  -1.149  -1.149  -1.230
346   L        -1.627  -1.641  -1.414  -1.748  -1.740  -1.399  -1.578  -1.567  -1.276
347   G        -0.872  -0.811  -0.880  -1.037  -0.950  -1.015  -1.006  -0.939  -0.976
348   I        -2.381  -2.360  -2.133  -2.323  -2.293  -1.953  -1.864  -1.830  -1.545
349   F        -1.107  -1.103  -0.918  -1.269  -1.298  -1.017  -1.292  -1.280  -1.021
350   K        -2.118  -2.064  -1.817  -2.240  -2.183  -1.783  -1.807  -1.743  -1.443
351   K        -0.862  -0.898  -0.881  -0.984  -1.053  -1.058  -0.966  -1.014  -0.974
352   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
353   D        -1.032  -1.030  -0.903  -1.046  -1.083  -0.869  -1.194  -1.191  -1.002
354   T        -1.061  -1.037  -0.903  -1.350  -1.307  -1.065  -1.246  -1.204  -1.002
355   P        -1.589  -1.601  -1.419  -1.518  -1.532  -1.284  -1.526  -1.528  -1.280
356   K        -1.589  -1.601  -1.419  -1.747  -1.781  -1.497  -1.526  -1.528  -1.280
357   P        -1.061  -1.006  -0.904  -1.266  -1.200  -1.004  -1.246  -1.169  -1.004
358   K        -0.862  -0.938  -0.889  -0.869  -0.982  -0.904  -0.966  -1.064  -0.984
359   P        -1.589  -1.587  -1.411  -1.657  -1.673  -1.384  -1.526  -1.514  -1.272
360   L        -1.589  -1.601  -1.419  -1.724  -1.737  -1.446  -1.526  -1.528  -1.280
361   K        -2.118  -2.064  -1.817  -1.968  -1.908  -1.542  -1.807  -1.743  -1.443
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P33303
Output conservation file - output/P33303
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
