1     M         1.866   1.877   1.952   2.032   2.052   2.164   2.063   2.079   2.196
2     S         0.995   1.082   0.898   0.992   1.113   0.853   0.983   1.123   0.789
3     T        -0.535  -0.602  -0.623  -0.491  -0.598  -0.644  -0.528  -0.609  -0.621
4     F         0.636   0.713   0.728   0.499   0.642   0.642   0.336   0.477   0.468
5     S         0.190   0.091   0.030   0.207   0.059  -0.046   0.120  -0.025  -0.122
6     A        -1.150  -1.179  -1.135  -1.159  -1.211  -1.148  -0.959  -0.983  -0.911
7     S        -0.088  -0.032  -0.065  -0.207  -0.134  -0.154  -0.312  -0.247  -0.273
8     D        -0.088  -0.037  -0.078  -0.279  -0.208  -0.250  -0.312  -0.250  -0.293
9     F         1.866   1.877   1.952   1.881   1.902   2.013   2.063   2.079   2.196
10    N         0.190   0.133   0.032   0.315   0.230   0.040   0.120   0.034  -0.119
11    S         0.190   0.220   0.077   0.204   0.248   0.029   0.120   0.160  -0.052
12    E        -1.596  -1.568  -1.503  -1.413  -1.388  -1.271  -1.175  -1.147  -1.056
13    R        -0.703  -0.737  -0.680  -0.655  -0.725  -0.634  -0.743  -0.771  -0.688
14    Y         1.866   1.877   1.952   1.877   1.907   2.010   2.063   2.079   2.196
15    S        -0.535  -0.485  -0.590  -0.531  -0.460  -0.625  -0.528  -0.471  -0.582
16    S        -1.596  -1.568  -1.503  -1.590  -1.536  -1.447  -1.175  -1.147  -1.056
17    S        -0.088  -0.059  -0.075  -0.246  -0.213  -0.222  -0.312  -0.289  -0.289
18    R         1.866   1.877   1.952   1.935   1.942   2.068   2.063   2.079   2.196
19    P         1.866   1.877   1.952   1.899   1.916   2.032   2.063   2.079   2.196
20    S         0.995   1.082   0.898   1.015   1.134   0.887   0.983   1.123   0.789
21    Y         1.866   1.877   1.952   1.877   1.907   2.010   2.063   2.079   2.196
22    P         1.866   1.877   1.952   1.899   1.916   2.032   2.063   2.079   2.196
23    S        -0.703  -0.674  -0.655  -0.741  -0.700  -0.669  -0.743  -0.709  -0.665
24    D        -1.150  -1.133  -1.099  -1.159  -1.139  -1.088  -0.959  -0.940  -0.879
25    F         0.190   0.091   0.030   0.311   0.165   0.072   0.120  -0.025  -0.122
26    Y         1.866   1.877   1.952   1.877   1.907   2.010   2.063   2.079   2.196
27    K        -1.150  -1.156  -1.103  -1.134  -1.152  -1.059  -0.959  -0.962  -0.882
28    M        -1.150  -1.133  -1.099  -1.021  -0.996  -0.939  -0.959  -0.940  -0.879
29    I         0.190   0.130   0.036   0.226   0.129  -0.014   0.120   0.031  -0.112
30    D        -1.150  -1.179  -1.135  -1.142  -1.191  -1.131  -0.959  -0.983  -0.911
31    E        -0.088  -0.043  -0.071  -0.197  -0.142  -0.169  -0.312  -0.266  -0.282
32    Y         0.636   0.597   0.643   0.497   0.432   0.478   0.336   0.253   0.300
33    H         1.866   1.877   1.952   2.008   2.030   2.140   2.063   2.079   2.196
34    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    D        -0.535  -0.534  -0.579  -0.576  -0.572  -0.659  -0.528  -0.529  -0.569
37    G         0.190   0.181   0.067   0.260   0.232   0.072   0.120   0.101  -0.066
38    E        -0.703  -0.624  -0.656  -0.765  -0.641  -0.699  -0.743  -0.662  -0.665
39    R        -0.088  -0.031  -0.079  -0.158  -0.094  -0.149  -0.312  -0.245  -0.293
40    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
45    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
46    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
47    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
48    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
49    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
50    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    K        -0.703  -0.694  -0.661  -0.753  -0.727  -0.685  -0.743  -0.730  -0.670
54    L         0.190   0.133   0.032   0.223   0.132  -0.026   0.120   0.034  -0.119
55    L        -0.088  -0.064  -0.056  -0.248  -0.206  -0.183  -0.312  -0.265  -0.253
56    V        -0.088  -0.080  -0.072  -0.229  -0.225  -0.205  -0.312  -0.303  -0.284
57    D         1.866   1.877   1.952   1.750   1.768   1.883   2.063   2.079   2.196
58    V        -0.088  -0.096  -0.069  -0.216  -0.217  -0.178  -0.312  -0.306  -0.271
59    G         1.866   1.877   1.952   1.853   1.862   1.986   2.063   2.079   2.196
60    C         1.866   1.877   1.952   2.100   2.119   2.232   2.063   2.079   2.196
61    G         1.866   1.877   1.952   1.853   1.862   1.986   2.063   2.079   2.196
62    P        -0.088  -0.096  -0.069  -0.164  -0.144  -0.105  -0.312  -0.306  -0.271
63    G         1.866   1.877   1.952   1.853   1.862   1.986   2.063   2.079   2.196
64    T        -0.088  -0.096  -0.069  -0.214  -0.207  -0.177  -0.312  -0.306  -0.271
65    A         0.527   0.540   0.616   0.251   0.263   0.390   0.120   0.140   0.247
66    T         0.527   0.540   0.616   0.242   0.262   0.382   0.120   0.140   0.247
67    L         0.190   0.130   0.036   0.289   0.201   0.050   0.120   0.031  -0.112
68    Q        -0.535  -0.565  -0.584  -0.418  -0.479  -0.529  -0.528  -0.567  -0.575
69    M         0.190   0.169   0.043   0.268   0.231   0.058   0.120   0.088  -0.102
70    A        -1.150  -1.086  -1.095  -1.083  -0.996  -0.999  -0.959  -0.893  -0.874
71    Q        -1.596  -1.568  -1.503  -1.396  -1.355  -1.254  -1.175  -1.147  -1.056
72    E        -0.535  -0.504  -0.569  -0.427  -0.367  -0.482  -0.528  -0.490  -0.557
73    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
74    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
75    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
76    F         1.866   1.877   1.952   1.881   1.902   2.013   2.063   2.079   2.196
77    E        -0.703  -0.740  -0.659  -0.843  -0.878  -0.764  -0.743  -0.774  -0.668
78    Q        -0.703  -0.621  -0.656  -0.671  -0.553  -0.604  -0.743  -0.658  -0.665
79    I         0.190   0.212   0.049   0.268   0.301   0.048   0.120   0.151  -0.094
80    I         0.995   1.014   0.872   1.046   1.075   0.866   0.983   1.011   0.741
81    G         0.995   0.919   0.861   1.035   0.916   0.834   0.983   0.849   0.720
82    S        -1.150  -1.179  -1.135  -1.051  -1.104  -1.021  -0.959  -0.983  -0.911
83    D         1.866   1.877   1.952   1.750   1.768   1.883   2.063   2.079   2.196
84    L        -0.703  -0.684  -0.653  -0.695  -0.667  -0.607  -0.743  -0.719  -0.663
85    S         1.866   1.877   1.952   1.809   1.831   1.943   2.063   2.079   2.196
86    A        -0.703  -0.696  -0.668  -0.776  -0.763  -0.698  -0.743  -0.729  -0.675
87    T        -0.088  -0.140  -0.097  -0.196  -0.272  -0.208  -0.312  -0.377  -0.317
88    M         1.866   1.877   1.952   2.032   2.052   2.164   2.063   2.079   2.196
89    I         0.995   1.071   0.896   1.046   1.151   0.903   0.983   1.105   0.784
90    K        -0.535  -0.469  -0.560  -0.511  -0.408  -0.563  -0.528  -0.446  -0.547
91    T        -0.088  -0.102  -0.092  -0.128  -0.140  -0.147  -0.312  -0.325  -0.308
92    A         0.636   0.713   0.728   0.568   0.679   0.710   0.336   0.477   0.468
93    E        -0.703  -0.703  -0.657  -0.677  -0.680  -0.609  -0.743  -0.738  -0.666
94    V        -0.703  -0.653  -0.658  -0.835  -0.762  -0.761  -0.743  -0.690  -0.667
95    I        -1.150  -1.106  -1.105  -1.021  -0.972  -0.959  -0.959  -0.915  -0.884
96    K        -0.535  -0.526  -0.572  -0.513  -0.509  -0.584  -0.528  -0.520  -0.561
97    E        -1.596  -1.568  -1.503  -1.462  -1.422  -1.319  -1.175  -1.147  -1.056
98    G        -1.150  -1.179  -1.135  -1.143  -1.211  -1.145  -0.959  -0.983  -0.911
99    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
100   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
101   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
102   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
103   D        -0.143  -0.101  -0.102  -0.226  -0.153  -0.181  -0.366  -0.306  -0.314
104   T        -0.143  -0.101  -0.102  -0.292  -0.226  -0.230  -0.366  -0.306  -0.314
105   Y        -1.596  -1.568  -1.503  -1.442  -1.397  -1.300  -1.175  -1.147  -1.056
106   K         0.995   0.919   0.861   0.970   0.871   0.766   0.983   0.849   0.720
107   N        -0.088  -0.109  -0.071  -0.159  -0.183  -0.139  -0.312  -0.338  -0.283
108   V         0.636   0.632   0.661   0.473   0.461   0.489   0.336   0.321   0.336
109   S        -1.150  -1.156  -1.103  -1.034  -1.047  -0.952  -0.959  -0.962  -0.882
110   F         0.995   0.964   0.868   1.070   1.033   0.883   0.983   0.927   0.733
111   K        -0.708  -0.624  -0.657  -0.689  -0.560  -0.603  -0.735  -0.635  -0.660
112   I        -1.150  -1.087  -1.097  -0.990  -0.878  -0.918  -0.959  -0.895  -0.877
113   S         0.995   1.011   0.874   1.029   1.045   0.844   0.983   1.007   0.743
114   S        -1.150  -1.151  -1.101  -1.138  -1.145  -1.063  -0.959  -0.958  -0.880
115   S        -0.535  -0.543  -0.612  -0.511  -0.534  -0.650  -0.528  -0.537  -0.608
116   D        -0.088  -0.080  -0.091  -0.248  -0.241  -0.246  -0.312  -0.304  -0.309
117   D         0.190   0.324   0.079   0.220   0.401   0.078   0.120   0.313  -0.050
118   F        -1.150  -1.087  -1.097  -1.069  -0.988  -0.984  -0.959  -0.895  -0.877
119   K        -0.703  -0.698  -0.670  -0.799  -0.788  -0.750  -0.743  -0.730  -0.677
120   F         0.779   0.784   0.762   0.741   0.749   0.692   0.606   0.608   0.535
121   L         0.779   0.784   0.762   0.650   0.653   0.610   0.606   0.608   0.535
122   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
123   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
124   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
125   D        -1.244  -1.220  -1.151  -1.287  -1.255  -1.145  -1.046  -1.019  -0.925
126   S        -0.708  -0.714  -0.667  -0.747  -0.755  -0.680  -0.735  -0.740  -0.671
127   V         0.030  -0.018  -0.055  -0.008  -0.088  -0.166  -0.113  -0.184  -0.247
128   D        -1.150  -1.086  -1.095  -1.190  -1.100  -1.102  -0.959  -0.893  -0.874
129   K        -0.257  -0.234  -0.157  -0.593  -0.557  -0.444  -0.528  -0.497  -0.393
130   Q        -0.088  -0.080  -0.091  -0.063  -0.050  -0.068  -0.312  -0.304  -0.309
131   K        -0.703  -0.737  -0.680  -0.854  -0.896  -0.806  -0.743  -0.771  -0.688
132   I        -0.535  -0.543  -0.612  -0.384  -0.401  -0.491  -0.528  -0.537  -0.608
133   D         1.866   1.877   1.952   1.750   1.768   1.883   2.063   2.079   2.196
134   M        -0.088  -0.130  -0.095  -0.075  -0.122  -0.049  -0.312  -0.361  -0.313
135   I         0.190   0.133   0.032   0.256   0.167   0.004   0.120   0.034  -0.119
136   T         0.995   0.919   0.861   1.040   0.938   0.841   0.983   0.849   0.720
137   A        -0.703  -0.696  -0.668  -0.642  -0.634  -0.550  -0.743  -0.729  -0.675
138   V        -0.088  -0.130  -0.095  -0.223  -0.296  -0.232  -0.312  -0.361  -0.313
139   E         0.995   0.919   0.861   1.057   0.957   0.874   0.983   0.849   0.720
140   C         0.636   0.614   0.648   0.683   0.629   0.656   0.336   0.286   0.311
141   A        -0.088  -0.028  -0.047  -0.087  -0.009  -0.022  -0.312  -0.218  -0.240
142   H         1.866   1.877   1.952   2.008   2.030   2.140   2.063   2.079   2.196
143   W         1.866   1.877   1.952   2.023   2.038   2.155   2.063   2.079   2.196
144   F        -0.088  -0.064  -0.056  -0.141  -0.082  -0.063  -0.312  -0.265  -0.253
145   D         0.995   1.082   0.898   0.956   1.072   0.830   0.983   1.123   0.789
146   F        -1.150  -1.179  -1.135  -0.922  -0.969  -0.914  -0.959  -0.983  -0.911
147   E        -0.703  -0.740  -0.659  -0.880  -0.929  -0.813  -0.743  -0.774  -0.668
148   K        -0.535  -0.494  -0.569  -0.503  -0.439  -0.553  -0.528  -0.479  -0.557
149   F         0.190   0.091   0.030   0.280   0.133   0.026   0.120  -0.025  -0.122
150   Q        -0.703  -0.737  -0.680  -0.626  -0.664  -0.573  -0.743  -0.771  -0.688
151   R        -1.596  -1.568  -1.503  -1.471  -1.425  -1.328  -1.175  -1.147  -1.056
152   S        -1.150  -1.179  -1.135  -1.087  -1.136  -1.062  -0.959  -0.983  -0.911
153   A        -0.703  -0.717  -0.676  -0.818  -0.840  -0.766  -0.743  -0.751  -0.684
154   Y        -0.703  -0.650  -0.653  -0.709  -0.633  -0.619  -0.743  -0.684  -0.662
155   A        -0.535  -0.543  -0.612  -0.463  -0.492  -0.623  -0.528  -0.537  -0.608
156   N        -0.703  -0.684  -0.653  -0.749  -0.719  -0.665  -0.743  -0.719  -0.663
157   L         0.995   0.919   0.861   1.012   0.897   0.814   0.983   0.849   0.720
158   R        -0.535  -0.543  -0.612  -0.470  -0.477  -0.576  -0.528  -0.537  -0.608
159   K        -1.150  -1.138  -1.100  -1.128  -1.108  -1.050  -0.959  -0.944  -0.879
160   D        -0.703  -0.703  -0.657  -0.701  -0.701  -0.627  -0.743  -0.738  -0.666
161   G         1.866   1.877   1.952   1.853   1.862   1.986   2.063   2.079   2.196
162   T         1.866   1.877   1.952   1.853   1.878   1.986   2.063   2.079   2.196
163   I         0.995   1.011   0.874   1.011   1.029   0.833   0.983   1.007   0.743
164   A         1.866   1.877   1.952   1.844   1.853   1.977   2.063   2.079   2.196
165   I        -0.703  -0.737  -0.680  -0.748  -0.786  -0.703  -0.743  -0.771  -0.688
166   W         1.866   1.877   1.952   2.023   2.038   2.155   2.063   2.079   2.196
167   G         0.636   0.713   0.728   0.475   0.602   0.618   0.336   0.477   0.468
168   Y         1.866   1.877   1.952   1.877   1.907   2.010   2.063   2.079   2.196
169   A        -0.535  -0.543  -0.612  -0.540  -0.549  -0.668  -0.528  -0.537  -0.608
170   D         1.866   1.877   1.952   1.750   1.768   1.883   2.063   2.079   2.196
171   P         0.190   0.133   0.032   0.329   0.247   0.092   0.120   0.034  -0.119
172   I        -0.088  -0.083  -0.065  -0.213  -0.198  -0.175  -0.312  -0.295  -0.273
173   F         0.190   0.133   0.032   0.271   0.185   0.015   0.120   0.034  -0.119
174   P        -0.088  -0.030  -0.049  -0.195  -0.094  -0.115  -0.312  -0.221  -0.242
175   D         0.527   0.540   0.616   0.174   0.187   0.311   0.120   0.140   0.247
176   Y        -0.535  -0.565  -0.584  -0.384  -0.429  -0.453  -0.528  -0.567  -0.575
177   P         0.995   1.071   0.896   1.063   1.169   0.908   0.983   1.105   0.784
178   E         0.995   1.071   0.896   1.019   1.129   0.870   0.983   1.105   0.784
179   F        -0.703  -0.737  -0.680  -0.780  -0.830  -0.738  -0.743  -0.771  -0.688
180   D        -0.088  -0.096  -0.069  -0.249  -0.249  -0.211  -0.312  -0.306  -0.271
181   D        -1.150  -1.105  -1.105  -1.156  -1.084  -1.079  -0.959  -0.914  -0.884
182   L        -1.150  -1.115  -1.097  -1.113  -1.059  -1.037  -0.959  -0.922  -0.877
183   M        -0.703  -0.698  -0.670  -0.683  -0.660  -0.612  -0.743  -0.730  -0.677
184   I        -1.150  -1.179  -1.135  -1.107  -1.160  -1.087  -0.959  -0.983  -0.911
185   E        -1.150  -1.179  -1.135  -1.069  -1.122  -1.074  -0.959  -0.983  -0.911
186   V        -0.703  -0.717  -0.676  -0.771  -0.787  -0.721  -0.743  -0.751  -0.684
187   P        -0.535  -0.604  -0.619  -0.431  -0.532  -0.558  -0.528  -0.611  -0.616
188   Y         1.866   1.877   1.952   1.877   1.907   2.010   2.063   2.079   2.196
189   G         0.636   0.713   0.728   0.510   0.633   0.653   0.336   0.477   0.468
190   K        -0.703  -0.717  -0.676  -0.910  -0.923  -0.863  -0.743  -0.751  -0.684
191   Q        -0.535  -0.604  -0.619  -0.490  -0.599  -0.619  -0.528  -0.611  -0.616
192   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
193   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
194   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
195   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
196   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
197   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
198   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
199   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
200   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
201   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
202   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
203   G        -0.703  -0.716  -0.676  -0.801  -0.817  -0.763  -0.743  -0.750  -0.684
204   L         0.636   0.632   0.661   0.613   0.598   0.616   0.336   0.321   0.336
205   G         0.995   0.919   0.861   1.073   0.965   0.896   0.983   0.849   0.720
206   P         0.995   0.919   0.861   1.132   1.034   0.962   0.983   0.849   0.720
207   Y         0.995   0.919   0.861   1.067   0.972   0.870   0.983   0.849   0.720
208   W         0.636   0.713   0.728   0.628   0.769   0.771   0.336   0.477   0.468
209   E        -0.088  -0.089  -0.093  -0.143  -0.157  -0.175  -0.312  -0.319  -0.312
210   Q         1.866   1.877   1.952   1.984   2.003   2.116   2.063   2.079   2.196
211   P         1.866   1.877   1.952   1.899   1.916   2.032   2.063   2.079   2.196
212   G         1.866   1.877   1.952   1.853   1.862   1.986   2.063   2.079   2.196
213   R        -0.088  -0.028  -0.047  -0.083   0.011  -0.018  -0.312  -0.218  -0.240
214   S        -1.150  -1.179  -1.135  -1.123  -1.144  -1.076  -0.959  -0.983  -0.911
215   R        -0.257  -0.234  -0.157  -0.418  -0.383  -0.263  -0.528  -0.497  -0.393
216   L         1.866   1.877   1.952   1.825   1.837   1.958   2.063   2.079   2.196
217   R         1.866   1.877   1.952   1.935   1.942   2.068   2.063   2.079   2.196
218   N        -0.703  -0.621  -0.656  -0.796  -0.681  -0.726  -0.743  -0.658  -0.665
219   M        -0.535  -0.572  -0.617  -0.489  -0.555  -0.621  -0.528  -0.573  -0.614
220   L        -0.257  -0.234  -0.157  -0.379  -0.355  -0.240  -0.528  -0.497  -0.392
221   K        -0.535  -0.602  -0.623  -0.504  -0.601  -0.637  -0.528  -0.609  -0.621
222   D        -0.535  -0.543  -0.612  -0.487  -0.500  -0.619  -0.528  -0.537  -0.608
223   S        -0.703  -0.698  -0.670  -0.795  -0.786  -0.741  -0.743  -0.730  -0.677
224   H        -1.150  -1.179  -1.135  -0.988  -1.032  -0.946  -0.959  -0.983  -0.911
225   L        -0.703  -0.673  -0.664  -0.750  -0.703  -0.682  -0.743  -0.705  -0.671
226   D        -0.088  -0.102  -0.092  -0.253  -0.272  -0.271  -0.312  -0.325  -0.308
227   P        -0.088  -0.098  -0.093  -0.213  -0.234  -0.219  -0.312  -0.333  -0.313
228   E        -1.150  -1.133  -1.099  -1.177  -1.144  -1.100  -0.959  -0.940  -0.879
229   L        -1.150  -1.127  -1.110  -1.088  -1.050  -1.023  -0.959  -0.935  -0.889
230   F         0.190   0.181   0.067   0.323   0.317   0.149   0.120   0.101  -0.066
231   H        -1.150  -1.152  -1.097  -1.096  -1.088  -1.009  -0.959  -0.959  -0.877
232   D         0.190   0.181   0.067   0.213   0.203   0.052   0.120   0.101  -0.066
233   I         0.527   0.540   0.616   0.262   0.282   0.401   0.120   0.139   0.246
234   Q        -0.535  -0.543  -0.612  -0.406  -0.419  -0.520  -0.528  -0.537  -0.608
235   V         0.190   0.169   0.043   0.326   0.279   0.087   0.120   0.088  -0.102
236   S         0.030  -0.039  -0.055   0.129   0.015  -0.044  -0.113  -0.216  -0.247
237   Y        -0.708  -0.749  -0.702  -0.786  -0.858  -0.786  -0.735  -0.779  -0.710
238   F        -0.708  -0.749  -0.702  -0.687  -0.737  -0.673  -0.735  -0.779  -0.710
239   C        -0.708  -0.670  -0.660  -0.745  -0.684  -0.662  -0.735  -0.690  -0.664
240   A         0.030   0.094   0.001   0.040   0.139  -0.027  -0.113  -0.022  -0.165
241   E        -1.244  -1.215  -1.151  -1.261  -1.194  -1.119  -1.046  -1.015  -0.925
242   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
243   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
244   R         1.866   1.877   1.952   1.874   1.886   2.007   2.063   2.079   2.196
245   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
246   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
247   V        -1.150  -1.138  -1.100  -1.070  -1.062  -0.994  -0.959  -0.944  -0.879
248   K        -1.150  -1.179  -1.135  -1.008  -1.075  -1.016  -0.959  -0.983  -0.911
249   L        -0.535  -0.604  -0.619  -0.508  -0.632  -0.661  -0.528  -0.611  -0.616
250   H        -1.150  -1.179  -1.135  -1.018  -1.066  -0.981  -0.959  -0.983  -0.911
251   Q        -0.535  -0.461  -0.562  -0.530  -0.423  -0.564  -0.528  -0.437  -0.549
252   H        -1.596  -1.568  -1.503  -1.444  -1.390  -1.301  -1.175  -1.147  -1.056
253   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
254   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
255   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
256   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
257   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
258   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
259   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
260   T        -0.535  -0.602  -0.623  -0.505  -0.607  -0.664  -0.528  -0.609  -0.621
261   K         0.190   0.091   0.030   0.216   0.082  -0.023   0.120  -0.025  -0.122
262   K        -0.088  -0.091  -0.093  -0.242  -0.246  -0.258  -0.312  -0.321  -0.313
263   P        -0.535  -0.532  -0.578  -0.441  -0.443  -0.521  -0.528  -0.527  -0.568
264   L         0.995   0.919   0.861   1.010   0.897   0.810   0.983   0.849   0.720
265   L        -1.596  -1.568  -1.503  -1.400  -1.349  -1.258  -1.175  -1.147  -1.056
266   I         0.190   0.091   0.030   0.292   0.147   0.056   0.120  -0.025  -0.122
267   R        -1.150  -1.086  -1.095  -0.997  -0.898  -0.916  -0.959  -0.893  -0.874
268   K         0.190   0.133   0.032   0.212   0.137  -0.026   0.120   0.034  -0.119
269   Q        -0.535  -0.534  -0.579  -0.440  -0.433  -0.508  -0.528  -0.529  -0.569
270   V        -0.703  -0.717  -0.676  -0.661  -0.675  -0.610  -0.743  -0.751  -0.684
271   T         0.190   0.133   0.032   0.246   0.164  -0.007   0.120   0.034  -0.119
272   L         0.995   1.082   0.898   1.046   1.153   0.925   0.983   1.123   0.789
273   V        -1.596  -1.568  -1.503  -1.546  -1.506  -1.403  -1.175  -1.147  -1.056
274   E        -0.703  -0.650  -0.653  -0.734  -0.676  -0.645  -0.743  -0.686  -0.663
275   F         0.636   0.614   0.648   0.475   0.427   0.460   0.336   0.286   0.311
276   A        -0.703  -0.696  -0.668  -0.781  -0.779  -0.709  -0.743  -0.729  -0.675
277   D        -0.535  -0.565  -0.584  -0.584  -0.638  -0.663  -0.528  -0.567  -0.575
278   Y         1.866   1.877   1.952   1.877   1.907   2.010   2.063   2.079   2.196
279   V        -0.088  -0.121  -0.096  -0.208  -0.263  -0.223  -0.312  -0.356  -0.316
280   R        -0.088  -0.064  -0.056  -0.185  -0.128  -0.119  -0.312  -0.265  -0.253
281   T         0.636   0.713   0.728   0.442   0.589   0.586   0.336   0.477   0.468
282   W         0.995   0.919   0.861   1.211   1.100   1.009   0.983   0.849   0.720
283   S         1.866   1.877   1.952   1.809   1.831   1.943   2.063   2.079   2.196
284   A         0.190   0.171   0.040   0.229   0.190  -0.012   0.120   0.091  -0.106
285   Y         0.995   0.919   0.861   1.067   0.972   0.870   0.983   0.849   0.720
286   H         0.995   0.919   0.861   1.182   1.076   0.972   0.983   0.849   0.720
287   Q        -1.150  -1.179  -1.135  -1.048  -1.093  -1.018  -0.959  -0.983  -0.911
288   W         1.866   1.877   1.952   2.023   2.038   2.155   2.063   2.079   2.196
289   K        -0.703  -0.737  -0.680  -0.655  -0.705  -0.618  -0.743  -0.771  -0.688
290   Q        -0.703  -0.716  -0.676  -0.655  -0.661  -0.594  -0.743  -0.750  -0.684
291   -        -0.813  -0.775  -0.721  -0.905  -0.870  -0.765  -0.851  -0.808  -0.730
292   -         1.866   1.877   1.952   1.999   2.025   2.132   2.063   2.079   2.196
293   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
294   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
295   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
296   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
297   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
298   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
299   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
300   D         0.779   0.784   0.762   0.606   0.620   0.577   0.606   0.608   0.535
301   P        -0.143  -0.167  -0.114  -0.267  -0.317  -0.241  -0.366  -0.402  -0.331
302   K        -0.813  -0.793  -0.721  -0.928  -0.897  -0.787  -0.851  -0.826  -0.730
303   N         0.779   0.736   0.749   0.849   0.774   0.777   0.606   0.519   0.508
304   K        -0.535  -0.543  -0.612  -0.541  -0.568  -0.693  -0.528  -0.537  -0.608
305   D         0.190   0.220   0.077   0.137   0.179  -0.039   0.120   0.160  -0.052
306   K         0.190   0.091   0.030   0.182   0.043  -0.074   0.120  -0.025  -0.122
307   E        -1.150  -1.179  -1.135  -1.023  -1.065  -0.996  -0.959  -0.983  -0.911
308   D         0.995   0.964   0.868   0.956   0.917   0.784   0.983   0.927   0.733
309   V        -0.703  -0.698  -0.670  -0.797  -0.796  -0.738  -0.743  -0.730  -0.677
310   A        -0.535  -0.602  -0.623  -0.435  -0.540  -0.565  -0.528  -0.609  -0.621
311   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
312   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
313   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
314   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
315   D        -0.535  -0.604  -0.619  -0.522  -0.634  -0.677  -0.528  -0.611  -0.616
316   W        -1.150  -1.115  -1.097  -1.081  -1.030  -1.000  -0.959  -0.922  -0.877
317   F         0.190   0.133   0.032   0.274   0.188   0.019   0.120   0.034  -0.119
318   I        -0.088  -0.081  -0.091  -0.226  -0.226  -0.233  -0.312  -0.305  -0.309
319   K        -1.150  -1.133  -1.099  -0.993  -0.965  -0.922  -0.959  -0.940  -0.879
320   E         0.190   0.171   0.040   0.267   0.242   0.042   0.120   0.091  -0.106
321   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
322   L        -0.535  -0.602  -0.623  -0.455  -0.560  -0.584  -0.528  -0.609  -0.621
323   R        -0.535  -0.543  -0.612  -0.541  -0.546  -0.669  -0.528  -0.537  -0.608
324   R        -1.596  -1.568  -1.503  -1.472  -1.448  -1.330  -1.175  -1.147  -1.056
325   R        -1.150  -1.115  -1.097  -1.094  -1.041  -1.015  -0.959  -0.922  -0.877
326   P        -1.150  -1.179  -1.135  -0.921  -0.982  -0.919  -0.959  -0.983  -0.911
327   E        -0.703  -0.698  -0.670  -0.783  -0.786  -0.739  -0.743  -0.730  -0.677
328   L        -0.703  -0.716  -0.676  -0.655  -0.689  -0.616  -0.743  -0.750  -0.684
329   S        -1.150  -1.152  -1.097  -1.130  -1.125  -1.041  -0.959  -0.959  -0.877
330   T        -0.703  -0.717  -0.676  -0.889  -0.901  -0.830  -0.743  -0.751  -0.684
331   N        -1.150  -1.087  -1.097  -1.060  -0.949  -0.977  -0.959  -0.895  -0.877
332   T        -1.150  -1.156  -1.103  -1.164  -1.177  -1.101  -0.959  -0.962  -0.882
333   K        -0.088  -0.102  -0.092  -0.269  -0.282  -0.279  -0.312  -0.325  -0.308
334   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
335   I        -0.088  -0.007  -0.063  -0.200  -0.075  -0.157  -0.312  -0.200  -0.270
336   E        -0.703  -0.703  -0.654  -0.850  -0.848  -0.768  -0.743  -0.737  -0.664
337   V         0.995   0.919   0.861   1.048   0.933   0.846   0.983   0.849   0.720
338   V        -0.257  -0.241  -0.166  -0.482  -0.465  -0.342  -0.528  -0.506  -0.405
339   W         1.866   1.877   1.952   2.023   2.038   2.155   2.063   2.079   2.196
340   N        -1.596  -1.568  -1.503  -1.576  -1.530  -1.433  -1.175  -1.147  -1.056
341   T         0.995   1.014   0.872   1.029   1.064   0.842   0.983   1.011   0.741
342   F         0.636   0.653   0.668   0.486   0.512   0.517   0.336   0.362   0.351
343   Y         0.190   0.091   0.030   0.264   0.118   0.003   0.120  -0.025  -0.122
344   K        -0.703  -0.673  -0.664  -0.821  -0.771  -0.757  -0.743  -0.705  -0.671
345   L        -0.088  -0.141  -0.095  -0.164  -0.236  -0.162  -0.312  -0.378  -0.314
346   G         0.995   1.011   0.874   1.028   1.042   0.849   0.983   1.007   0.743
347   K         0.527   0.540   0.616   0.267   0.285   0.403   0.120   0.139   0.245
348   R         0.527   0.547   0.621   0.267   0.309   0.425   0.120   0.154   0.257
349   V        -0.535  -0.572  -0.617  -0.511  -0.563  -0.638  -0.528  -0.573  -0.614
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P32643
Output conservation file - output/P32643
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
