1     M         0.987   1.002   1.065   1.164   1.184   1.259   1.037   1.059   1.150
2     F        -2.479  -2.303  -2.145  -2.294  -2.071  -1.844  -1.920  -1.772  -1.528
3     S        -2.086  -1.890  -1.809  -1.945  -1.677  -1.561  -1.772  -1.591  -1.413
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     L        -2.204  -2.108  -1.832  -2.285  -2.164  -1.754  -1.861  -1.765  -1.430
10    P        -1.655  -1.663  -1.428  -1.588  -1.622  -1.298  -1.571  -1.572  -1.267
11    T        -1.018  -0.918  -0.882  -1.157  -1.027  -0.937  -1.177  -1.066  -0.965
12    S        -1.477  -1.501  -1.400  -1.538  -1.640  -1.505  -1.378  -1.407  -1.240
13    L        -2.566  -2.464  -2.160  -2.517  -2.433  -1.957  -1.982  -1.887  -1.538
14    A        -1.650  -1.488  -1.408  -1.853  -1.583  -1.519  -1.579  -1.415  -1.249
15    R        -1.693  -1.574  -1.416  -1.900  -1.778  -1.465  -1.624  -1.507  -1.256
16    N        -2.086  -1.994  -1.817  -1.812  -1.718  -1.483  -1.772  -1.678  -1.419
17    V        -2.086  -1.964  -1.814  -1.953  -1.797  -1.569  -1.772  -1.659  -1.417
18    A        -1.301  -1.393  -1.394  -1.325  -1.464  -1.370  -1.181  -1.293  -1.234
19    R        -1.545  -1.498  -1.395  -1.401  -1.316  -1.193  -1.476  -1.406  -1.235
20    R        -0.908  -0.887  -0.862  -0.989  -0.956  -0.939  -1.033  -0.983  -0.938
21    A         0.174   0.052  -0.105  -0.036  -0.208  -0.432   0.150  -0.038  -0.325
22    P        -2.479  -2.404  -2.150  -2.367  -2.275  -1.955  -1.920  -1.849  -1.532
23    T        -2.086  -1.972  -1.814  -1.811  -1.693  -1.471  -1.772  -1.668  -1.417
24    S        -0.908  -1.011  -0.889  -1.104  -1.293  -1.107  -1.033  -1.158  -0.973
25    F        -2.108  -2.048  -1.823  -2.199  -2.160  -1.811  -1.780  -1.718  -1.424
26    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
45    V        -1.655  -1.637  -1.427  -1.943  -1.971  -1.631  -1.571  -1.547  -1.266
46    R        -1.655  -1.625  -1.418  -1.610  -1.638  -1.320  -1.571  -1.535  -1.257
47    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
48    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
49    A        -1.655  -1.560  -1.410  -1.859  -1.738  -1.456  -1.571  -1.467  -1.250
50    A        -1.655  -1.578  -1.411  -1.619  -1.521  -1.313  -1.571  -1.485  -1.250
51    A        -1.105  -1.087  -0.896  -1.364  -1.327  -1.019  -1.281  -1.251  -0.981
52    A        -1.655  -1.510  -1.406  -1.559  -1.344  -1.257  -1.571  -1.410  -1.246
53    A        -0.367  -0.338  -0.182  -0.870  -0.829  -0.536  -0.737  -0.699  -0.462
54    L        -2.479  -2.312  -2.146  -2.289  -2.060  -1.841  -1.920  -1.778  -1.529
55    R        -1.545  -1.579  -1.414  -1.500  -1.615  -1.364  -1.476  -1.501  -1.254
56    F        -1.545  -1.445  -1.400  -1.449  -1.319  -1.214  -1.476  -1.358  -1.241
57    S        -1.545  -1.536  -1.405  -1.733  -1.700  -1.436  -1.476  -1.449  -1.246
58    S        -1.004  -0.916  -0.871  -1.166  -1.024  -0.919  -1.181  -1.059  -0.950
59    T        -0.908  -0.893  -0.885  -0.932  -0.945  -0.931  -1.033  -1.030  -0.968
60    K         0.174   0.228  -0.090   0.336   0.405  -0.037   0.150   0.226  -0.300
61    T        -0.908  -1.015  -0.891  -0.911  -1.079  -0.916  -1.033  -1.164  -0.975
62    M        -0.472  -0.535  -0.843  -0.078  -0.161  -0.653  -0.434  -0.522  -0.913
63    T         0.987   1.002   1.065   1.022   1.072   1.135   1.037   1.059   1.150
64    V         0.987   1.002   1.065   0.859   0.873   0.992   1.037   1.059   1.150
65    R         0.987   1.002   1.065   1.082   1.134   1.188   1.037   1.059   1.150
66    E        -0.325  -0.162  -0.143  -0.500  -0.230  -0.229  -0.661  -0.388  -0.392
67    A         0.987   1.002   1.065   0.703   0.744   0.856   1.037   1.059   1.150
68    L         0.987   1.002   1.065   0.910   0.934   1.037   1.037   1.059   1.150
69    N         0.987   1.002   1.065   1.136   1.147   1.235   1.037   1.059   1.150
70    S        -1.142  -1.260  -1.374  -0.902  -1.029  -1.244  -1.000  -1.137  -1.214
71    A         0.987   1.002   1.065   0.703   0.744   0.856   1.037   1.059   1.150
72    M        -0.387  -0.345  -0.182  -0.560  -0.503  -0.249  -0.774  -0.711  -0.462
73    A        -1.142  -1.273  -1.376  -1.180  -1.340  -1.478  -1.000  -1.152  -1.216
74    E         0.987   1.002   1.065   0.908   0.920   1.035   1.037   1.059   1.150
75    E         0.987   1.002   1.065   0.908   0.920   1.035   1.037   1.059   1.150
76    L        -0.325  -0.324  -0.179  -0.484  -0.479  -0.250  -0.661  -0.672  -0.456
77    D        -0.472  -0.683  -0.857  -0.226  -0.544  -0.842  -0.434  -0.711  -0.930
78    R         0.240   0.136  -0.102   0.408   0.293  -0.203   0.245   0.089  -0.321
79    D        -0.128  -0.214  -0.164  -0.061  -0.229  -0.152  -0.321  -0.479  -0.429
80    D         0.240   0.287  -0.090   0.398   0.435  -0.124   0.245   0.309  -0.299
81    D        -1.142  -1.385  -1.389  -0.779  -1.131  -1.145  -1.000  -1.273  -1.229
82    V         0.987   1.002   1.065   0.859   0.873   0.992   1.037   1.059   1.150
83    F         0.987   1.002   1.065   1.069   1.089   1.176   1.037   1.059   1.150
84    L        -0.945  -0.970  -0.869  -1.109  -1.149  -0.983  -1.114  -1.118  -0.950
85    I        -0.387  -0.340  -0.182  -0.495  -0.418  -0.185  -0.774  -0.702  -0.461
86    G         0.987   1.002   1.065   0.937   0.934   1.060   1.037   1.059   1.150
87    E         0.987   1.002   1.065   0.908   0.920   1.035   1.037   1.059   1.150
88    E         0.987   1.002   1.065   0.908   0.920   1.035   1.037   1.059   1.150
89    V         0.987   1.002   1.065   0.859   0.873   0.992   1.037   1.059   1.150
90    A         0.240   0.167  -0.078   0.058  -0.021  -0.369   0.245   0.136  -0.279
91    Q         0.987   1.002   1.065   1.162   1.188   1.257   1.037   1.059   1.150
92    Y         0.987   1.002   1.065   1.138   1.154   1.236   1.037   1.059   1.150
93    N         0.987   1.002   1.065   1.136   1.147   1.235   1.037   1.059   1.150
94    G         0.987   1.002   1.065   0.937   0.934   1.060   1.037   1.059   1.150
95    A         0.987   1.002   1.065   0.703   0.744   0.856   1.037   1.059   1.150
96    Y         0.987   1.002   1.065   1.138   1.154   1.236   1.037   1.059   1.150
97    K         0.987   1.002   1.065   1.022   1.047   1.135   1.037   1.059   1.150
98    V        -0.128  -0.152  -0.168  -0.284  -0.344  -0.364  -0.321  -0.371  -0.436
99    S        -0.387  -0.349  -0.182  -0.634  -0.519  -0.311  -0.774  -0.718  -0.461
100   K        -0.325  -0.309  -0.181  -0.428  -0.394  -0.226  -0.661  -0.645  -0.461
101   G         0.987   1.002   1.065   0.937   0.934   1.060   1.037   1.059   1.150
102   L         0.987   1.002   1.065   0.910   0.934   1.037   1.037   1.059   1.150
103   L         0.987   1.002   1.065   0.910   0.934   1.037   1.037   1.059   1.150
104   D         0.987   1.002   1.065   1.045   1.046   1.155   1.037   1.059   1.150
105   R        -0.325  -0.336  -0.181  -0.407  -0.426  -0.222  -0.661  -0.694  -0.460
106   F         0.987   1.002   1.065   1.069   1.089   1.176   1.037   1.059   1.150
107   G         0.987   1.002   1.065   0.937   0.934   1.060   1.037   1.059   1.150
108   E        -0.472  -0.683  -0.857  -0.335  -0.633  -0.869  -0.434  -0.711  -0.930
109   R        -0.325  -0.336  -0.181  -0.407  -0.426  -0.222  -0.661  -0.694  -0.460
110   R         0.987   1.002   1.065   1.082   1.134   1.188   1.037   1.059   1.150
111   V         0.987   1.002   1.065   0.859   0.873   0.992   1.037   1.059   1.150
112   V        -0.387  -0.334  -0.171  -0.714  -0.633  -0.349  -0.774  -0.691  -0.443
113   D         0.987   1.002   1.065   1.045   1.046   1.155   1.037   1.059   1.150
114   T         0.987   1.002   1.065   1.022   1.072   1.135   1.037   1.059   1.150
115   P         0.987   1.002   1.065   1.049   1.065   1.158   1.037   1.059   1.150
116   I         0.987   1.002   1.065   1.002   1.010   1.117   1.037   1.059   1.150
117   T         0.987   1.002   1.065   1.022   1.072   1.135   1.037   1.059   1.150
118   E         0.987   1.002   1.065   0.908   0.920   1.035   1.037   1.059   1.150
119   Y        -0.128   0.064  -0.117   0.049   0.327   0.013  -0.321  -0.021  -0.346
120   G         0.987   1.002   1.065   0.937   0.934   1.060   1.037   1.059   1.150
121   F         0.987   1.002   1.065   1.069   1.089   1.176   1.037   1.059   1.150
122   T        -0.128  -0.089  -0.148  -0.220  -0.133  -0.359  -0.321  -0.266  -0.401
123   G         0.987   1.002   1.065   0.937   0.934   1.060   1.037   1.059   1.150
124   L         0.240   0.167  -0.078   0.255   0.160  -0.231   0.245   0.136  -0.279
125   A         0.240   0.167  -0.078   0.109   0.047  -0.227   0.245   0.136  -0.279
126   V         0.240   0.119  -0.102   0.228   0.073  -0.245   0.245   0.064  -0.320
127   G         0.987   1.002   1.065   0.937   0.934   1.060   1.037   1.059   1.150
128   A         0.240   0.324  -0.087   0.060   0.188  -0.379   0.245   0.360  -0.294
129   A         0.987   1.002   1.065   0.703   0.744   0.856   1.037   1.059   1.150
130   L         0.240   0.119  -0.102   0.286   0.137  -0.185   0.245   0.064  -0.320
131   K        -1.502  -1.474  -1.401  -1.602  -1.562  -1.374  -1.453  -1.397  -1.242
132   G         0.987   1.002   1.065   0.937   0.934   1.060   1.037   1.059   1.150
133   L         0.987   1.002   1.065   0.910   0.934   1.037   1.037   1.059   1.150
134   K        -1.142  -1.385  -1.389  -0.777  -1.088  -1.113  -1.000  -1.273  -1.229
135   P         0.987   1.002   1.065   1.049   1.065   1.158   1.037   1.059   1.150
136   I        -0.325  -0.333  -0.181  -0.564  -0.631  -0.374  -0.661  -0.689  -0.460
137   V        -0.945  -0.793  -0.862  -0.887  -0.600  -0.768  -1.114  -0.896  -0.938
138   E         0.987   1.002   1.065   0.908   0.920   1.035   1.037   1.059   1.150
139   F         0.987   1.002   1.065   1.069   1.089   1.176   1.037   1.059   1.150
140   M         0.987   1.002   1.065   1.160   1.188   1.256   1.037   1.059   1.150
141   S        -0.325  -0.162  -0.143  -0.499  -0.167  -0.226  -0.661  -0.388  -0.392
142   F        -0.128  -0.141  -0.151   0.011  -0.016  -0.037  -0.321  -0.353  -0.405
143   N         0.987   1.002   1.065   1.136   1.147   1.235   1.037   1.059   1.150
144   F         0.987   1.002   1.065   1.069   1.089   1.176   1.037   1.059   1.150
145   S        -0.387  -0.340  -0.182  -0.870  -0.761  -0.521  -0.774  -0.702  -0.461
146   M         0.987   1.002   1.065   1.160   1.188   1.256   1.037   1.059   1.150
147   Q         0.987   1.002   1.065   1.162   1.188   1.257   1.037   1.059   1.150
148   A        -0.798  -0.776  -0.875  -1.058  -1.008  -1.129  -0.887  -0.871  -0.957
149   I         0.240   0.378  -0.082   0.391   0.533  -0.043   0.245   0.432  -0.286
150   D         0.987   1.002   1.065   1.045   1.046   1.155   1.037   1.059   1.150
151   H        -0.325  -0.274  -0.168  -0.188  -0.118  -0.002  -0.661  -0.583  -0.437
152   V        -0.325  -0.162  -0.143  -0.564  -0.283  -0.286  -0.661  -0.388  -0.392
153   V        -0.945  -0.875  -0.865  -1.140  -1.062  -0.989  -1.114  -1.024  -0.945
154   N         0.987   1.002   1.065   1.136   1.147   1.235   1.037   1.059   1.150
155   S         0.987   1.002   1.065   0.948   1.024   1.070   1.037   1.059   1.150
156   A         0.240   0.167  -0.078   0.058  -0.021  -0.369   0.245   0.136  -0.279
157   A         0.987   1.002   1.065   0.703   0.744   0.856   1.037   1.059   1.150
158   K         0.240   0.119  -0.102   0.400   0.258  -0.091   0.245   0.064  -0.320
159   T         0.987   1.002   1.065   1.022   1.072   1.135   1.037   1.059   1.150
160   H        -1.159  -1.025  -0.891  -1.151  -1.014  -0.776  -1.340  -1.182  -0.975
161   Y         0.987   1.002   1.065   1.138   1.154   1.236   1.037   1.059   1.150
162   M         0.987   1.002   1.065   1.160   1.188   1.256   1.037   1.059   1.150
163   S         0.987   1.002   1.065   0.948   1.024   1.070   1.037   1.059   1.150
164   G         0.987   1.002   1.065   0.937   0.934   1.060   1.037   1.059   1.150
165   G         0.987   1.002   1.065   0.937   0.934   1.060   1.037   1.059   1.150
166   T        -1.075  -1.075  -0.910  -1.120  -1.135  -0.908  -1.227  -1.234  -0.997
167   Q         0.987   1.002   1.065   1.162   1.188   1.257   1.037   1.059   1.150
168   K        -1.502  -1.555  -1.395  -1.435  -1.505  -1.289  -1.453  -1.472  -1.236
169   C         0.987   1.002   1.065   1.268   1.280   1.350   1.037   1.059   1.150
170   Q        -0.945  -0.923  -0.872  -0.789  -0.736  -0.685  -1.114  -1.043  -0.952
171   M        -0.472  -0.402  -0.809  -0.254  -0.208  -0.756  -0.434  -0.360  -0.869
172   V        -0.387  -0.340  -0.182  -0.699  -0.598  -0.363  -0.774  -0.702  -0.461
173   F         0.987   1.002   1.065   1.069   1.089   1.176   1.037   1.059   1.150
174   R         0.987   1.002   1.065   1.082   1.134   1.188   1.037   1.059   1.150
175   G         0.987   1.002   1.065   0.937   0.934   1.060   1.037   1.059   1.150
176   P         0.987   1.002   1.065   1.049   1.065   1.158   1.037   1.059   1.150
177   N         0.987   1.002   1.065   1.136   1.147   1.235   1.037   1.059   1.150
178   G         0.987   1.002   1.065   0.937   0.934   1.060   1.037   1.059   1.150
179   A        -1.418  -1.465  -1.395  -1.569  -1.571  -1.445  -1.340  -1.362  -1.236
180   A         0.987   1.002   1.065   0.703   0.744   0.856   1.037   1.059   1.150
181   V        -0.325  -0.162  -0.143  -0.835  -0.541  -0.517  -0.661  -0.388  -0.392
182   G         0.240   0.119  -0.102   0.261   0.068  -0.322   0.245   0.064  -0.320
183   V         0.987   1.002   1.065   0.859   0.873   0.992   1.037   1.059   1.150
184   G        -0.128   0.019  -0.148  -0.459  -0.229  -0.485  -0.321  -0.091  -0.401
185   A         0.987   1.002   1.065   0.703   0.744   0.856   1.037   1.059   1.150
186   Q         0.987   1.002   1.065   1.162   1.188   1.257   1.037   1.059   1.150
187   H         0.987   1.002   1.065   1.253   1.264   1.337   1.037   1.059   1.150
188   S         0.987   1.002   1.065   0.948   1.024   1.070   1.037   1.059   1.150
189   Q         0.987   1.002   1.065   1.162   1.188   1.257   1.037   1.059   1.150
190   D        -0.798  -0.838  -0.875  -0.549  -0.609  -0.617  -0.887  -0.921  -0.955
191   F        -0.325  -0.320  -0.179  -0.334  -0.353  -0.153  -0.661  -0.666  -0.456
192   S        -0.945  -0.974  -0.879  -1.230  -1.220  -1.088  -1.114  -1.134  -0.963
193   P        -0.798  -0.852  -0.865  -1.016  -1.086  -1.060  -0.887  -0.950  -0.944
194   W         0.987   1.002   1.065   1.288   1.303   1.367   1.037   1.059   1.150
195   Y         0.987   1.002   1.065   1.138   1.154   1.236   1.037   1.059   1.150
196   G         0.987   1.002   1.065   0.937   0.934   1.060   1.037   1.059   1.150
197   S         0.240   0.167  -0.078   0.338   0.307  -0.078   0.245   0.136  -0.279
198   I        -0.128  -0.117  -0.166  -0.192  -0.201  -0.338  -0.321  -0.311  -0.434
199   P         0.987   1.002   1.065   1.049   1.065   1.158   1.037   1.059   1.150
200   G         0.987   1.002   1.065   0.937   0.934   1.060   1.037   1.059   1.150
201   L         0.240   0.378  -0.082   0.299   0.458  -0.115   0.245   0.432  -0.286
202   K         0.987   1.002   1.065   1.022   1.047   1.135   1.037   1.059   1.150
203   V         0.987   1.002   1.065   0.859   0.873   0.992   1.037   1.059   1.150
204   L        -0.325  -0.348  -0.183  -0.647  -0.730  -0.442  -0.661  -0.716  -0.463
205   V        -0.325  -0.162  -0.143  -0.612  -0.269  -0.327  -0.661  -0.388  -0.392
206   P         0.987   1.002   1.065   1.049   1.065   1.158   1.037   1.059   1.150
207   Y         0.240   0.136  -0.102   0.544   0.417   0.084   0.245   0.089  -0.321
208   S         0.987   1.002   1.065   0.948   1.024   1.070   1.037   1.059   1.150
209   A         0.240   0.167  -0.078   0.060  -0.004  -0.364   0.245   0.136  -0.279
210   E         0.987   1.002   1.065   0.908   0.920   1.035   1.037   1.059   1.150
211   D         0.987   1.002   1.065   1.045   1.046   1.155   1.037   1.059   1.150
212   A        -0.128  -0.050  -0.151  -0.389  -0.266  -0.379  -0.321  -0.202  -0.406
213   R        -0.387  -0.340  -0.182  -0.537  -0.448  -0.226  -0.774  -0.702  -0.461
214   G         0.987   1.002   1.065   0.937   0.934   1.060   1.037   1.059   1.150
215   L         0.987   1.002   1.065   0.910   0.934   1.037   1.037   1.059   1.150
216   L         0.240   0.324  -0.087   0.286   0.388  -0.161   0.245   0.360  -0.294
217   K         0.987   1.002   1.065   1.022   1.047   1.135   1.037   1.059   1.150
218   A         0.987   1.002   1.065   0.703   0.744   0.856   1.037   1.059   1.150
219   A         0.987   1.002   1.065   0.703   0.744   0.856   1.037   1.059   1.150
220   I         0.987   1.002   1.065   1.002   1.010   1.117   1.037   1.059   1.150
221   R         0.987   1.002   1.065   1.082   1.134   1.188   1.037   1.059   1.150
222   D         0.987   1.002   1.065   1.045   1.046   1.155   1.037   1.059   1.150
223   P         0.987   1.002   1.065   1.049   1.065   1.158   1.037   1.059   1.150
224   N         0.987   1.002   1.065   1.136   1.147   1.235   1.037   1.059   1.150
225   P         0.240   0.167  -0.078   0.395   0.291  -0.118   0.245   0.136  -0.279
226   V         0.240   0.167  -0.078   0.228   0.135  -0.206   0.245   0.136  -0.279
227   V         0.240   0.136  -0.102   0.225   0.083  -0.255   0.245   0.089  -0.321
228   F        -0.128  -0.236  -0.178  -0.125  -0.349  -0.318  -0.321  -0.516  -0.454
229   L         0.987   1.002   1.065   0.910   0.934   1.037   1.037   1.059   1.150
230   E         0.987   1.002   1.065   0.908   0.920   1.035   1.037   1.059   1.150
231   N         0.987   1.002   1.065   1.136   1.147   1.235   1.037   1.059   1.150
232   E         0.987   1.002   1.065   0.908   0.920   1.035   1.037   1.059   1.150
233   L        -0.945  -0.877  -0.878  -1.046  -0.980  -0.875  -1.114  -1.046  -0.961
234   L        -1.418  -1.377  -1.397  -1.384  -1.322  -1.387  -1.340  -1.315  -1.239
235   Y         0.987   1.002   1.065   1.138   1.154   1.236   1.037   1.059   1.150
236   G         0.987   1.002   1.065   0.937   0.934   1.060   1.037   1.059   1.150
237   E        -0.798  -0.889  -0.879  -0.759  -0.890  -0.845  -0.887  -0.995  -0.961
238   S        -1.418  -1.406  -1.398  -1.329  -1.308  -1.296  -1.340  -1.340  -1.240
239   F         0.987   1.002   1.065   1.069   1.089   1.176   1.037   1.059   1.150
240   E        -0.945  -0.893  -0.877  -1.047  -0.972  -0.894  -1.114  -1.054  -0.960
241   I        -1.159  -1.098  -0.911  -1.282  -1.170  -0.913  -1.340  -1.259  -0.998
242   S         0.987   1.002   1.065   0.948   1.024   1.070   1.037   1.059   1.150
243   E         0.240   0.119  -0.102   0.277   0.115  -0.207   0.245   0.064  -0.320
244   E         0.240   0.136  -0.102   0.231   0.078  -0.346   0.245   0.089  -0.321
245   A        -0.472  -0.311  -0.821  -0.554  -0.335  -1.001  -0.434  -0.235  -0.885
246   L        -1.142  -1.260  -1.374  -0.904  -1.043  -1.199  -1.000  -1.137  -1.214
247   S         0.240   0.136  -0.102   0.317   0.240  -0.176   0.245   0.089  -0.321
248   P        -1.762  -1.773  -1.800  -1.428  -1.486  -1.568  -1.453  -1.470  -1.405
249   E         0.240   0.401  -0.081   0.398   0.567  -0.107   0.245   0.463  -0.283
250   F         0.987   1.002   1.065   1.069   1.089   1.176   1.037   1.059   1.150
251   T        -0.945  -0.793  -0.862  -1.108  -0.876  -0.940  -1.114  -0.896  -0.938
252   L         0.240   0.136  -0.102   0.276   0.143  -0.215   0.245   0.089  -0.321
253   P         0.987   1.002   1.065   1.049   1.065   1.158   1.037   1.059   1.150
254   Y        -1.632  -1.628  -1.416  -1.507  -1.535  -1.244  -1.566  -1.545  -1.256
255   -         0.987   1.002   1.065   0.906   0.916   1.033   1.037   1.059   1.150
256   K        -0.472  -0.454  -0.834  -0.248  -0.245  -0.816  -0.434  -0.430  -0.901
257   A         0.987   1.002   1.065   0.703   0.744   0.856   1.037   1.059   1.150
258   K         0.987   1.002   1.065   1.022   1.047   1.135   1.037   1.059   1.150
259   I        -0.325  -0.272  -0.176  -0.564  -0.496  -0.360  -0.661  -0.580  -0.451
260   E         0.987   1.002   1.065   0.908   0.920   1.035   1.037   1.059   1.150
261   R        -0.128  -0.011  -0.151  -0.062   0.142  -0.161  -0.321  -0.138  -0.406
262   E        -0.472  -0.683  -0.857  -0.392  -0.705  -1.016  -0.434  -0.711  -0.930
263   G         0.987   1.002   1.065   0.937   0.934   1.060   1.037   1.059   1.150
264   T        -1.159  -1.104  -0.910  -1.292  -1.173  -0.933  -1.340  -1.267  -0.997
265   D         0.987   1.002   1.065   1.045   1.046   1.155   1.037   1.059   1.150
266   I        -0.128  -0.159  -0.170  -0.176  -0.254  -0.319  -0.321  -0.383  -0.441
267   S        -0.325  -0.162  -0.143  -0.499  -0.167  -0.226  -0.661  -0.388  -0.392
268   I        -0.128  -0.123  -0.147  -0.176  -0.192  -0.270  -0.321  -0.322  -0.400
269   V        -0.128   0.048  -0.120  -0.284  -0.038  -0.284  -0.321  -0.045  -0.351
270   T        -1.159  -1.055  -0.907  -1.350  -1.185  -0.978  -1.340  -1.212  -0.994
271   Y        -1.502  -1.572  -1.409  -1.168  -1.261  -1.067  -1.453  -1.488  -1.250
272   T        -0.387  -0.306  -0.173  -0.634  -0.444  -0.297  -0.774  -0.640  -0.445
273   R         0.240   0.119  -0.102   0.448   0.319  -0.078   0.245   0.064  -0.320
274   N        -1.142  -1.296  -1.392  -0.749  -0.968  -1.215  -1.000  -1.179  -1.233
275   V        -0.472  -0.297  -0.821  -0.411  -0.206  -0.917  -0.434  -0.218  -0.884
276   Q        -2.449  -2.418  -2.149  -2.172  -2.217  -1.795  -1.906  -1.859  -1.531
277   F        -1.418  -1.474  -1.403  -1.134  -1.234  -1.087  -1.340  -1.408  -1.245
278   S        -0.945  -0.877  -0.878  -1.174  -1.087  -0.985  -1.114  -1.046  -0.961
279   L        -0.472  -0.535  -0.843  -0.372  -0.465  -0.946  -0.434  -0.522  -0.913
280   E        -1.762  -1.731  -1.787  -1.606  -1.600  -1.703  -1.453  -1.428  -1.394
281   A         0.987   1.002   1.065   0.703   0.744   0.856   1.037   1.059   1.150
282   A         0.987   1.002   1.065   0.703   0.744   0.856   1.037   1.059   1.150
283   E        -0.798  -0.755  -0.863  -0.805  -0.820  -0.889  -0.887  -0.884  -0.942
284   I        -1.418  -1.542  -1.403  -1.374  -1.607  -1.434  -1.340  -1.459  -1.244
285   L         0.987   1.002   1.065   0.910   0.934   1.037   1.037   1.059   1.150
286   Q        -1.502  -1.266  -1.387  -1.479  -1.167  -1.266  -1.453  -1.220  -1.230
287   K        -1.142  -1.062  -1.368  -0.933  -0.852  -1.395  -1.000  -0.923  -1.208
288   K        -1.976  -1.891  -1.803  -1.673  -1.595  -1.423  -1.680  -1.604  -1.409
289   Y        -0.472  -0.507  -0.818  -0.070  -0.121  -0.559  -0.434  -0.484  -0.881
290   G         0.240   0.167  -0.078   0.323   0.210  -0.097   0.245   0.136  -0.279
291   V         0.240   0.287  -0.090   0.225   0.273  -0.234   0.245   0.309  -0.299
292   S        -1.632  -1.628  -1.416  -1.689  -1.675  -1.361  -1.566  -1.545  -1.256
293   A         0.240   0.136  -0.102   0.046  -0.075  -0.445   0.245   0.089  -0.321
294   E         0.987   1.002   1.065   0.908   0.920   1.035   1.037   1.059   1.150
295   V         0.987   1.002   1.065   0.859   0.873   0.992   1.037   1.059   1.150
296   I        -0.128  -0.159  -0.170  -0.176  -0.254  -0.319  -0.321  -0.383  -0.441
297   N         0.987   1.002   1.065   1.136   1.147   1.235   1.037   1.059   1.150
298   L         0.987   1.002   1.065   0.910   0.934   1.037   1.037   1.059   1.150
299   R         0.987   1.002   1.065   1.082   1.134   1.188   1.037   1.059   1.150
300   S        -0.472  -0.424  -0.806  -0.356  -0.235  -0.902  -0.434  -0.385  -0.865
301   I         0.240   0.167  -0.078   0.348   0.235  -0.156   0.245   0.136  -0.279
302   R        -0.387  -0.340  -0.182  -0.537  -0.448  -0.226  -0.774  -0.702  -0.461
303   P         0.987   1.002   1.065   1.049   1.065   1.158   1.037   1.059   1.150
304   L         0.987   1.002   1.065   0.910   0.934   1.037   1.037   1.059   1.150
305   D         0.987   1.002   1.065   1.045   1.046   1.155   1.037   1.059   1.150
306   T        -1.632  -1.622  -1.412  -1.702  -1.678  -1.398  -1.566  -1.535  -1.254
307   E        -1.502  -1.511  -1.392  -1.445  -1.468  -1.231  -1.453  -1.442  -1.235
308   A        -0.798  -0.810  -0.870  -1.025  -1.032  -1.077  -0.887  -0.939  -0.951
309   I         0.987   1.002   1.065   1.002   1.010   1.117   1.037   1.059   1.150
310   I        -1.976  -2.067  -1.812  -1.970  -2.160  -1.786  -1.680  -1.731  -1.416
311   K        -1.976  -1.946  -1.805  -1.733  -1.745  -1.527  -1.680  -1.641  -1.411
312   T        -0.325  -0.162  -0.143  -0.525  -0.194  -0.246  -0.661  -0.388  -0.392
313   V        -0.128  -0.214  -0.164  -0.284  -0.450  -0.358  -0.321  -0.479  -0.429
314   K         0.987   1.002   1.065   1.022   1.047   1.135   1.037   1.059   1.150
315   K         0.987   1.002   1.065   1.022   1.047   1.135   1.037   1.059   1.150
316   T         0.987   1.002   1.065   1.022   1.072   1.135   1.037   1.059   1.150
317   N         0.240   0.136  -0.102   0.538   0.403   0.068   0.245   0.089  -0.321
318   H        -0.325  -0.348  -0.183  -0.228  -0.300  -0.083  -0.661  -0.716  -0.463
319   L         0.240   0.119  -0.102   0.276   0.121  -0.215   0.245   0.064  -0.320
320   I        -0.945  -0.910  -0.873  -1.087  -1.010  -0.900  -1.114  -1.028  -0.953
321   T         0.240   0.167  -0.078   0.381   0.324  -0.104   0.245   0.136  -0.279
322   V         0.240   0.324  -0.087   0.265   0.352  -0.116   0.245   0.360  -0.294
323   E         0.240   0.119  -0.102   0.280   0.115  -0.197   0.245   0.064  -0.320
324   S        -1.418  -1.465  -1.399  -1.410  -1.435  -1.348  -1.340  -1.383  -1.241
325   T        -0.945  -0.923  -0.872  -1.105  -1.065  -1.024  -1.114  -1.043  -0.952
326   F         0.240   0.119  -0.102   0.455   0.303  -0.031   0.245   0.064  -0.320
327   P         0.240   0.119  -0.102   0.407   0.254  -0.127   0.245   0.064  -0.320
328   S        -1.502  -1.511  -1.397  -1.687  -1.633  -1.444  -1.453  -1.443  -1.239
329   F        -0.472  -0.683  -0.857  -0.126  -0.396  -0.634  -0.434  -0.711  -0.930
330   G         0.987   1.002   1.065   0.937   0.934   1.060   1.037   1.059   1.150
331   V        -0.472  -0.656  -0.833  -0.372  -0.623  -0.841  -0.434  -0.676  -0.900
332   G         0.987   1.002   1.065   0.937   0.934   1.060   1.037   1.059   1.150
333   A        -0.387  -0.338  -0.182  -0.870  -0.715  -0.510  -0.774  -0.699  -0.461
334   E         0.987   1.002   1.065   0.908   0.920   1.035   1.037   1.059   1.150
335   I         0.240   0.167  -0.078   0.355   0.246  -0.136   0.245   0.136  -0.279
336   V        -1.632  -1.596  -1.412  -1.559  -1.535  -1.341  -1.566  -1.507  -1.253
337   A         0.240   0.167  -0.078   0.058  -0.021  -0.369   0.245   0.136  -0.279
338   Q        -0.472  -0.642  -0.835  -0.135  -0.381  -0.780  -0.434  -0.656  -0.903
339   V        -0.945  -0.967  -0.872  -1.153  -1.193  -1.064  -1.114  -1.112  -0.953
340   M        -0.472  -0.642  -0.835  -0.101  -0.336  -0.693  -0.434  -0.656  -0.903
341   E         0.240   0.167  -0.078   0.280   0.177  -0.158   0.245   0.136  -0.279
342   S         0.987   1.002   1.065   0.939   1.020   1.062   1.037   1.059   1.150
343   E        -1.142  -1.385  -1.389  -0.865  -1.197  -1.138  -1.000  -1.273  -1.229
344   A         0.240   0.136  -0.102   0.058  -0.063  -0.410   0.245   0.089  -0.321
345   F         0.240   0.167  -0.078   0.476   0.391   0.067   0.245   0.136  -0.279
346   D         0.987   1.002   1.065   1.045   1.046   1.155   1.037   1.059   1.150
347   Y         0.240   0.136  -0.102   0.513   0.376  -0.007   0.245   0.089  -0.321
348   L         0.987   1.002   1.065   0.910   0.934   1.037   1.037   1.059   1.150
349   D         0.987   1.002   1.065   1.045   1.046   1.155   1.037   1.059   1.150
350   A         0.987   1.002   1.065   0.703   0.744   0.856   1.037   1.059   1.150
351   P         0.987   1.002   1.065   1.049   1.065   1.158   1.037   1.059   1.150
352   I        -0.945  -0.993  -0.883  -1.081  -1.170  -0.958  -1.114  -1.153  -0.967
353   Q        -0.325  -0.309  -0.181  -0.396  -0.393  -0.239  -0.661  -0.645  -0.461
354   R         0.987   1.002   1.065   1.082   1.134   1.188   1.037   1.059   1.150
355   V         0.987   1.002   1.065   0.859   0.873   0.992   1.037   1.059   1.150
356   T         0.240   0.119  -0.102   0.381   0.261  -0.148   0.245   0.064  -0.320
357   G         0.240   0.119  -0.102   0.326   0.158  -0.124   0.245   0.064  -0.320
358   A        -0.128  -0.050  -0.151  -0.343  -0.225  -0.309  -0.321  -0.202  -0.406
359   D        -0.387  -0.348  -0.180  -0.647  -0.608  -0.311  -0.774  -0.716  -0.457
360   V         0.987   1.002   1.065   0.859   0.873   0.992   1.037   1.059   1.150
361   P         0.987   1.002   1.065   1.049   1.065   1.158   1.037   1.059   1.150
362   T         0.240   0.119  -0.102   0.411   0.293  -0.058   0.245   0.064  -0.320
363   P         0.987   1.002   1.065   1.049   1.065   1.158   1.037   1.059   1.150
364   Y         0.987   1.002   1.065   1.138   1.154   1.236   1.037   1.059   1.150
365   A         0.240   0.119  -0.102   0.060  -0.066  -0.404   0.245   0.064  -0.320
366   K        -1.142  -1.385  -1.389  -0.766  -1.087  -1.090  -1.000  -1.273  -1.229
367   E        -0.472  -0.683  -0.857  -0.353  -0.660  -0.915  -0.434  -0.711  -0.930
368   L         0.240   0.119  -0.102   0.255   0.093  -0.276   0.245   0.064  -0.320
369   E         0.987   1.002   1.065   0.908   0.920   1.035   1.037   1.059   1.150
370   D        -1.142  -1.385  -1.389  -0.873  -1.284  -1.340  -1.000  -1.273  -1.229
371   F        -0.472  -0.683  -0.857  -0.211  -0.511  -0.848  -0.434  -0.711  -0.930
372   A         0.240   0.119  -0.102   0.060  -0.066  -0.404   0.245   0.064  -0.320
373   F         0.240   0.119  -0.102   0.416   0.248  -0.148   0.245   0.064  -0.320
374   P         0.987   1.002   1.065   1.049   1.065   1.158   1.037   1.059   1.150
375   D        -0.798  -0.958  -0.881  -0.663  -0.916  -0.793  -0.887  -1.095  -0.963
376   T        -1.976  -1.991  -1.810  -1.896  -1.961  -1.754  -1.680  -1.672  -1.415
377   P        -1.418  -1.377  -1.393  -1.362  -1.343  -1.313  -1.340  -1.305  -1.235
378   T        -1.632  -1.655  -1.419  -1.702  -1.766  -1.418  -1.566  -1.570  -1.259
379   I        -0.325  -0.331  -0.180  -0.564  -0.626  -0.371  -0.661  -0.686  -0.458
380   V        -1.142  -1.136  -1.380  -1.013  -1.040  -1.357  -1.000  -0.999  -1.220
381   K        -1.418  -1.540  -1.398  -1.248  -1.423  -1.284  -1.340  -1.450  -1.240
382   A         0.240   0.136  -0.102   0.107   0.006  -0.263   0.245   0.089  -0.321
383   V        -1.142  -0.912  -1.358  -1.149  -0.835  -1.396  -1.000  -0.741  -1.198
384   K        -0.472  -0.501  -0.840  -0.271  -0.327  -0.885  -0.434  -0.482  -0.909
385   E        -1.418  -1.244  -1.369  -1.321  -1.045  -1.267  -1.340  -1.131  -1.210
386   V        -1.142  -1.385  -1.389  -1.031  -1.391  -1.406  -1.000  -1.273  -1.229
387   L         0.987   1.002   1.065   0.910   0.934   1.037   1.037   1.059   1.150
388   S        -1.418  -1.474  -1.403  -1.291  -1.345  -1.266  -1.340  -1.408  -1.245
389   I        -0.325  -0.304  -0.182  -0.537  -0.531  -0.348  -0.661  -0.638  -0.462
390   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
391   E        -0.733  -0.899  -0.884  -0.686  -0.959  -0.930  -0.774  -0.997  -0.965
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P32473
Output conservation file - output/P32473
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
