1     M         1.897   1.928   2.075   2.075   2.122   2.351   2.088   2.134   2.379
2     W        -0.867  -0.821  -0.821  -0.974  -0.941  -0.865  -0.827  -0.765  -0.733
3     R        -0.568  -0.472  -0.456  -0.692  -0.531  -0.545  -0.711  -0.594  -0.566
4     L        -0.568  -0.537  -0.458  -0.845  -0.788  -0.672  -0.711  -0.673  -0.569
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     T        -0.347  -0.337  -0.389  -0.379  -0.407  -0.480  -0.463  -0.464  -0.496
7     R        -0.668  -0.759  -0.802  -0.554  -0.753  -0.857  -0.584  -0.685  -0.706
8     K        -1.630  -1.620  -1.530  -1.548  -1.511  -1.375  -1.192  -1.171  -1.044
9     I        -0.867  -0.827  -0.818  -0.794  -0.701  -0.719  -0.827  -0.770  -0.729
10    G        -1.309  -1.252  -1.210  -1.409  -1.343  -1.257  -1.070  -1.011  -0.922
11    T        -1.337  -1.264  -1.221  -1.181  -1.071  -1.013  -1.085  -1.011  -0.928
12    R        -0.970  -0.996  -0.882  -1.025  -1.092  -0.899  -0.926  -0.935  -0.792
13    I         0.790   0.883   0.889   0.407   0.550   0.542   0.501   0.666   0.598
14    H        -1.188  -1.206  -1.191  -0.914  -0.959  -0.925  -0.949  -0.960  -0.901
15    I        -1.630  -1.490  -1.514  -1.244  -1.029  -1.075  -1.192  -1.066  -1.032
16    S        -0.988  -0.992  -0.881  -1.093  -1.105  -0.941  -0.949  -0.933  -0.793
17    N        -1.309  -1.300  -1.216  -1.037  -0.998  -0.869  -1.070  -1.049  -0.927
18    Q        -1.309  -1.295  -1.224  -1.211  -1.203  -1.080  -1.070  -1.042  -0.932
19    L        -1.309  -1.327  -1.230  -1.363  -1.331  -1.197  -1.070  -1.068  -0.937
20    S        -0.347  -0.374  -0.382  -0.298  -0.332  -0.341  -0.463  -0.495  -0.487
21    P        -1.309  -1.298  -1.222  -1.245  -1.215  -1.110  -1.070  -1.044  -0.931
22    I        -0.867  -0.779  -0.812  -0.741  -0.630  -0.651  -0.827  -0.737  -0.726
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    F        -0.991  -1.002  -0.911  -1.029  -1.060  -0.945  -0.935  -0.938  -0.816
32    N         0.026   0.148   0.128  -0.100   0.107   0.039  -0.287  -0.109  -0.150
33    K        -0.991  -0.931  -0.876  -0.878  -0.775  -0.710  -0.935  -0.867  -0.782
34    A        -1.418  -1.371  -1.270  -1.242  -1.159  -1.020  -1.151  -1.099  -0.967
35    I        -0.402  -0.424  -0.424  -0.416  -0.481  -0.520  -0.503  -0.533  -0.526
36    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    P        -0.568  -0.557  -0.468  -0.686  -0.686  -0.549  -0.711  -0.697  -0.580
40    V         0.129   0.214   0.164  -0.041   0.076  -0.024  -0.133  -0.025  -0.100
41    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    R         0.424   0.513   0.306   0.589   0.711   0.409   0.343   0.470   0.139
43    F         0.424   0.513   0.306   0.575   0.703   0.383   0.343   0.470   0.139
44    Y        -0.237  -0.282  -0.333  -0.122  -0.228  -0.312  -0.292  -0.356  -0.412
45    S         0.129   0.049   0.119   0.054  -0.074   0.024  -0.133  -0.249  -0.168
46    S         0.424   0.290   0.250   0.567   0.388   0.323   0.343   0.138   0.050
47    S        -0.832  -0.652  -0.787  -0.697  -0.433  -0.642  -0.768  -0.561  -0.690
48    P        -0.402  -0.323  -0.374  -0.366  -0.250  -0.335  -0.503  -0.405  -0.465
49    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
50    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
57    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
58    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
59    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
60    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
61    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
62    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
63    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
64    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
65    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
66    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
67    -        -0.970  -0.943  -0.871  -1.036  -0.999  -0.877  -0.926  -0.889  -0.781
68    -        -0.832  -0.855  -0.834  -0.661  -0.706  -0.668  -0.768  -0.790  -0.740
69    -        -0.832  -0.818  -0.823  -0.729  -0.708  -0.732  -0.768  -0.748  -0.727
70    -         0.129   0.232   0.178   0.034   0.207   0.076  -0.133   0.016  -0.075
71    E        -0.867  -0.950  -0.863  -0.991  -1.072  -0.956  -0.827  -0.892  -0.774
72    Q        -0.867  -0.843  -0.852  -0.930  -0.923  -0.944  -0.827  -0.803  -0.764
73    K         0.095   0.170   0.150  -0.172  -0.076  -0.065  -0.220  -0.136  -0.134
74    Y         1.897   1.928   2.075   2.092   2.138   2.369   2.088   2.134   2.379
75    R        -0.867  -0.886  -0.828  -0.914  -0.919  -0.856  -0.827  -0.827  -0.739
76    K        -0.867  -0.832  -0.830  -0.861  -0.803  -0.825  -0.827  -0.795  -0.744
77    K         1.200   1.211   1.088   1.097   1.122   0.956   1.238   1.250   0.994
78    L         1.897   1.928   2.075   1.611   1.653   1.880   2.088   2.134   2.379
79    L        -0.867  -0.887  -0.858  -1.221  -1.252  -1.183  -0.827  -0.842  -0.770
80    E        -1.309  -1.320  -1.224  -1.326  -1.319  -1.201  -1.070  -1.063  -0.933
81    E         1.200   1.314   1.105   1.079   1.234   0.948   1.238   1.414   1.026
82    A         1.897   1.928   2.075   1.855   1.888   2.128   2.088   2.134   2.379
83    Q        -1.309  -1.269  -1.212  -1.356  -1.322  -1.212  -1.070  -1.025  -0.923
84    K         0.095   0.206   0.165  -0.209  -0.036  -0.105  -0.220  -0.072  -0.110
85    Q        -0.105  -0.034   0.062  -0.603  -0.501  -0.361  -0.463  -0.370  -0.247
86    G         1.200   1.112   1.077   1.431   1.325   1.294   1.238   1.083   0.974
87    F        -0.988  -0.994  -0.885  -1.071  -1.074  -0.908  -0.949  -0.935  -0.796
88    N        -0.604  -0.540  -0.477  -0.789  -0.673  -0.612  -0.768  -0.689  -0.596
89    S        -0.347  -0.427  -0.402  -0.307  -0.417  -0.385  -0.463  -0.554  -0.511
90    I        -0.347  -0.400  -0.390  -0.324  -0.398  -0.429  -0.463  -0.514  -0.495
91    E        -0.105  -0.089   0.039  -0.361  -0.309  -0.133  -0.463  -0.439  -0.276
92    E        -0.089  -0.191  -0.301  -0.080  -0.252  -0.450  -0.098  -0.237  -0.371
93    L         1.897   1.928   2.075   1.611   1.653   1.880   2.088   2.134   2.379
94    K         1.200   1.211   1.088   1.102   1.126   0.967   1.238   1.250   0.994
95    N        -0.988  -0.989  -0.883  -1.147  -1.134  -0.986  -0.949  -0.931  -0.794
96    H        -1.188  -1.142  -1.174  -1.113  -1.069  -1.064  -0.949  -0.903  -0.886
97    L        -0.089  -0.248  -0.316  -0.158  -0.368  -0.441  -0.098  -0.305  -0.390
98    K        -0.347  -0.394  -0.381  -0.530  -0.588  -0.566  -0.463  -0.506  -0.483
99    E        -0.347  -0.351  -0.350  -0.385  -0.367  -0.398  -0.463  -0.445  -0.440
100   T        -0.867  -0.739  -0.813  -0.999  -0.834  -0.912  -0.827  -0.704  -0.727
101   I         1.200   1.112   1.077   1.363   1.255   1.210   1.238   1.083   0.974
102   E         1.897   1.928   2.075   1.815   1.873   2.087   2.088   2.134   2.379
103   S        -1.188  -1.194  -1.184  -1.182  -1.175  -1.163  -0.949  -0.951  -0.895
104   K        -0.347  -0.435  -0.408  -0.567  -0.712  -0.675  -0.463  -0.570  -0.519
105   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
106   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
107   K         0.536   0.460   0.304   0.441   0.341   0.071   0.509   0.393   0.136
108   R         0.232   0.359   0.219  -0.085   0.106  -0.132   0.023   0.202  -0.013
109   E         0.536   0.443   0.307   0.549   0.435   0.187   0.509   0.366   0.139
110   F         0.095   0.056   0.139  -0.241  -0.279  -0.137  -0.220  -0.258  -0.148
111   N        -0.347  -0.421  -0.401  -0.262  -0.367  -0.345  -0.463  -0.549  -0.511
112   K        -0.970  -0.937  -0.878  -1.130  -1.077  -0.971  -0.926  -0.882  -0.787
113   I         0.424   0.308   0.226   0.577   0.402   0.247   0.343   0.163   0.012
114   D         1.139   1.044   1.018   1.233   1.105   1.058   1.136   0.965   0.859
115   P         1.139   1.044   1.018   1.249   1.106   1.037   1.136   0.965   0.859
116   L         1.139   1.125   1.038   0.937   0.924   0.800   1.136   1.105   0.899
117   K        -0.832  -0.891  -0.861  -0.928  -1.023  -0.976  -0.768  -0.826  -0.767
118   E         0.424   0.308   0.226   0.407   0.250   0.084   0.343   0.163   0.012
119   L         0.424   0.308   0.226   0.238   0.065  -0.071   0.343   0.163   0.012
120   E        -0.237  -0.362  -0.387  -0.335  -0.534  -0.648  -0.292  -0.451  -0.481
121   D        -0.604  -0.611  -0.480  -0.818  -0.831  -0.638  -0.768  -0.760  -0.599
122   Y        -0.832  -0.891  -0.861  -0.489  -0.597  -0.548  -0.768  -0.826  -0.767
123   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
124   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
125   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
126   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
127   Q        -0.832  -0.824  -0.829  -0.979  -0.967  -1.030  -0.768  -0.758  -0.734
128   Q        -0.832  -0.844  -0.848  -0.785  -0.833  -0.848  -0.768  -0.778  -0.754
129   K        -0.099  -0.060   0.044  -0.464  -0.417  -0.256  -0.450  -0.397  -0.269
130   T        -0.832  -0.845  -0.849  -0.727  -0.774  -0.786  -0.768  -0.779  -0.755
131   Q        -0.970  -0.905  -0.868  -1.067  -0.972  -0.919  -0.926  -0.856  -0.779
132   M        -0.970  -0.974  -0.887  -1.060  -1.102  -0.950  -0.926  -0.916  -0.795
133   E        -0.237  -0.148  -0.302  -0.209  -0.069  -0.306  -0.292  -0.176  -0.373
134   N        -1.703  -1.653  -1.558  -1.623  -1.598  -1.408  -1.244  -1.192  -1.063
135   N        -0.832  -0.844  -0.848  -0.734  -0.751  -0.799  -0.768  -0.778  -0.754
136   N        -0.991  -0.992  -0.902  -1.016  -1.018  -0.910  -0.935  -0.928  -0.808
137   S        -0.991  -0.963  -0.894  -1.059  -1.005  -0.944  -0.935  -0.900  -0.800
138   K        -0.563  -0.549  -0.466  -0.798  -0.767  -0.666  -0.719  -0.697  -0.583
139   H        -0.563  -0.578  -0.472  -0.564  -0.602  -0.441  -0.719  -0.725  -0.589
140   L        -0.402  -0.416  -0.398  -0.606  -0.618  -0.628  -0.503  -0.522  -0.495
141   M         0.424   0.585   0.304   0.608   0.816   0.448   0.343   0.580   0.136
142   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
143   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
144   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
145   T        -0.604  -0.584  -0.478  -0.801  -0.795  -0.636  -0.768  -0.735  -0.597
146   K         0.536   0.443   0.307   0.480   0.351   0.150   0.509   0.366   0.139
147   S        -1.630  -1.628  -1.543  -1.463  -1.485  -1.336  -1.192  -1.176  -1.053
148   R        -0.026  -0.051   0.043  -0.225  -0.300  -0.185  -0.341  -0.383  -0.270
149   S        -0.347  -0.256  -0.348  -0.342  -0.207  -0.360  -0.463  -0.346  -0.444
150   P        -1.188  -1.248  -1.209  -1.040  -1.171  -1.130  -0.949  -0.997  -0.917
151   L        -1.630  -1.619  -1.530  -1.672  -1.659  -1.569  -1.192  -1.169  -1.044
152   D        -0.668  -0.747  -0.799  -0.410  -0.524  -0.601  -0.584  -0.673  -0.702
153   P        -0.668  -0.646  -0.756  -0.477  -0.445  -0.653  -0.584  -0.560  -0.656
154   S        -1.309  -1.289  -1.222  -1.269  -1.217  -1.147  -1.070  -1.037  -0.930
155   A        -1.188  -1.104  -1.159  -1.064  -0.955  -1.026  -0.949  -0.862  -0.873
156   P         0.536   0.522   0.335   0.734   0.695   0.434   0.509   0.477   0.184
157   K         0.536   0.682   0.362   0.495   0.692   0.263   0.509   0.719   0.226
158   V        -1.630  -1.626  -1.536  -1.642  -1.673  -1.541  -1.192  -1.174  -1.048
159   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
160   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
161   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
162   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
163   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
164   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
165   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
166   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
167   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
168   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
169   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
170   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
171   P        -0.089  -0.246  -0.322   0.158  -0.068  -0.203  -0.098  -0.302  -0.398
172   F        -0.547  -0.555  -0.450  -0.612  -0.656  -0.491  -0.706  -0.701  -0.567
173   K         1.200   1.112   1.077   1.093   0.986   0.932   1.238   1.083   0.974
174   T        -0.867  -0.949  -0.866  -0.720  -0.823  -0.696  -0.827  -0.892  -0.777
175   L         1.897   1.928   2.075   1.611   1.653   1.880   2.088   2.134   2.379
176   D         0.536   0.369   0.292   0.715   0.495   0.362   0.509   0.258   0.116
177   S        -0.668  -0.749  -0.792  -0.486  -0.611  -0.687  -0.584  -0.675  -0.695
178   F         0.095   0.049   0.132   0.130   0.081   0.215  -0.220  -0.271  -0.158
179   L        -0.026  -0.029   0.049  -0.412  -0.410  -0.285  -0.341  -0.351  -0.261
180   D         0.232   0.270   0.200   0.173   0.251   0.097   0.023   0.086  -0.040
181   V         0.095   0.060   0.135  -0.178  -0.205  -0.107  -0.220  -0.251  -0.154
182   G        -0.867  -0.843  -0.823  -0.854  -0.811  -0.765  -0.827  -0.793  -0.735
183   K         1.897   1.928   2.075   1.714   1.764   1.984   2.088   2.134   2.379
184   L        -0.988  -0.924  -0.876  -1.171  -1.063  -0.979  -0.949  -0.881  -0.789
185   K         1.200   1.131   1.071   1.102   1.022   0.940   1.238   1.115   0.961
186   D         0.095   0.162   0.146  -0.078   0.001   0.006  -0.220  -0.151  -0.141
187   L         1.897   1.928   2.075   1.611   1.653   1.880   2.088   2.134   2.379
188   S         0.095   0.161   0.162   0.025   0.156   0.169  -0.220  -0.105  -0.105
189   K        -0.668  -0.761  -0.805  -0.718  -0.847  -0.944  -0.584  -0.687  -0.709
190   Q        -0.347  -0.427  -0.402  -0.399  -0.526  -0.522  -0.463  -0.554  -0.511
191   E         0.536   0.440   0.318   0.595   0.481   0.293   0.509   0.362   0.157
192   V        -0.547  -0.441  -0.440  -0.674  -0.531  -0.505  -0.706  -0.583  -0.555
193   E         0.536   0.457   0.306   0.593   0.503   0.271   0.509   0.389   0.139
194   F         0.232   0.123   0.152   0.197  -0.004  -0.002   0.023  -0.142  -0.117
195   L         0.673   0.685   0.793   0.222   0.237   0.403   0.266   0.271   0.396
196   W         1.897   1.928   2.075   2.158   2.204   2.436   2.088   2.134   2.379
197   R         1.200   1.211   1.088   1.357   1.372   1.218   1.238   1.250   0.994
198   A         1.200   1.131   1.071   1.193   1.080   0.975   1.238   1.115   0.961
199   R         1.200   1.301   1.098   1.323   1.456   1.169   1.238   1.394   1.014
200   W        -0.867  -0.949  -0.866  -0.496  -0.608  -0.479  -0.827  -0.892  -0.777
201   A        -0.426  -0.319  -0.387  -0.482  -0.340  -0.399  -0.584  -0.468  -0.499
202   Q        -0.089  -0.167  -0.285   0.167   0.060  -0.112  -0.098  -0.209  -0.350
203   K        -0.466  -0.334  -0.390  -0.553  -0.311  -0.411  -0.609  -0.438  -0.490
204   D         0.232   0.197   0.174   0.213   0.183   0.100   0.023  -0.017  -0.082
205   N        -0.547  -0.544  -0.448  -0.530  -0.508  -0.365  -0.706  -0.687  -0.564
206   T        -0.988  -0.960  -0.879  -1.006  -0.973  -0.832  -0.949  -0.911  -0.791
207   L         1.200   1.284   1.097   1.015   1.119   0.910   1.238   1.367   1.012
208   C        -0.867  -0.838  -0.812  -0.547  -0.490  -0.455  -0.827  -0.784  -0.724
209   A         1.897   1.928   2.075   1.855   1.888   2.128   2.088   2.134   2.379
210   V         0.536   0.440   0.318   0.761   0.654   0.491   0.509   0.362   0.157
211   I        -0.105  -0.061   0.045  -0.410  -0.327  -0.202  -0.463  -0.401  -0.269
212   P        -0.089  -0.045  -0.269   0.172   0.232  -0.092  -0.098  -0.040  -0.330
213   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
214   V        -1.630  -1.626  -1.536  -1.393  -1.414  -1.253  -1.192  -1.174  -1.048
215   S        -1.309  -1.182  -1.213  -1.574  -1.355  -1.417  -1.070  -0.953  -0.924
216   V        -0.988  -0.931  -0.876  -1.025  -0.948  -0.867  -0.949  -0.888  -0.789
217   Y         0.095   0.163   0.146   0.167   0.244   0.286  -0.220  -0.150  -0.140
218   D        -1.309  -1.257  -1.214  -1.260  -1.190  -1.098  -1.070  -1.016  -0.925
219   K        -0.668  -0.633  -0.765  -0.665  -0.626  -0.802  -0.584  -0.544  -0.666
220   M         0.536   0.620   0.357   0.805   0.915   0.520   0.509   0.627   0.218
221   M        -1.188  -1.191  -1.178  -0.873  -0.930  -0.893  -0.949  -0.948  -0.890
222   A        -0.867  -0.884  -0.851  -0.995  -1.035  -1.012  -0.827  -0.840  -0.764
223   N        -0.347  -0.360  -0.369  -0.370  -0.406  -0.423  -0.463  -0.480  -0.473
224   A         1.200   1.214   1.083   1.252   1.263   1.116   1.238   1.255   0.984
225   R        -0.347  -0.195  -0.332  -0.289  -0.066  -0.277  -0.463  -0.278  -0.422
226   N        -0.668  -0.674  -0.761  -0.656  -0.654  -0.782  -0.584  -0.597  -0.661
227   N        -0.347  -0.435  -0.408  -0.161  -0.280  -0.218  -0.463  -0.570  -0.519
228   P         1.897   1.928   2.075   1.979   2.022   2.254   2.088   2.134   2.379
229   I        -1.630  -1.530  -1.514  -1.383  -1.208  -1.210  -1.192  -1.102  -1.032
230   F         1.897   1.928   2.075   1.986   2.036   2.261   2.088   2.134   2.379
231   V         1.200   1.284   1.097   1.326   1.444   1.205   1.238   1.367   1.012
232   L         1.200   1.308   1.104   1.000   1.134   0.890   1.238   1.405   1.025
233   P         1.897   1.928   2.075   1.979   2.022   2.254   2.088   2.134   2.379
234   L         1.200   1.131   1.071   0.994   0.907   0.827   1.238   1.115   0.961
235   P         1.200   1.284   1.097   1.351   1.458   1.214   1.238   1.367   1.012
236   R         0.095   0.058   0.128  -0.086  -0.126  -0.020  -0.220  -0.255  -0.162
237   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
238   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
239   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
240   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
241   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
242   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
243   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
244   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
245   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
246   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
247   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
248   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
249   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
250   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
251   E        -1.309  -1.226  -1.211  -1.128  -0.993  -0.979  -1.070  -0.991  -0.923
252   E        -0.347  -0.325  -0.380  -0.408  -0.379  -0.452  -0.463  -0.451  -0.485
253   Q        -1.309  -1.266  -1.217  -1.267  -1.222  -1.139  -1.070  -1.023  -0.927
254   G         0.536   0.705   0.369   0.796   1.016   0.561   0.509   0.752   0.236
255   M        -1.309  -1.320  -1.234  -0.924  -0.953  -0.805  -1.070  -1.063  -0.940
256   E         1.897   1.928   2.075   1.815   1.873   2.087   2.088   2.134   2.379
257   L        -0.426  -0.509  -0.401  -0.570  -0.665  -0.501  -0.584  -0.654  -0.514
258   H         0.536   0.613   0.351   0.840   0.943   0.564   0.509   0.618   0.208
259   Y         0.095   0.161   0.162   0.130   0.244   0.258  -0.220  -0.105  -0.105
260   I        -0.026  -0.003   0.080  -0.268  -0.283  -0.167  -0.341  -0.319  -0.215
261   Q         1.897   1.928   2.075   1.935   1.989   2.210   2.088   2.134   2.379
262   W         1.897   1.928   2.075   2.158   2.204   2.436   2.088   2.134   2.379
263   Q        -0.347  -0.389  -0.400  -0.284  -0.352  -0.365  -0.463  -0.523  -0.508
264   F         1.200   1.131   1.071   1.401   1.327   1.265   1.238   1.115   0.961
265   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
266   V        -0.347  -0.374  -0.382  -0.310  -0.359  -0.366  -0.463  -0.495  -0.487
267   G         0.536   0.369   0.292   0.793   0.559   0.428   0.509   0.258   0.116
268   P        -0.089  -0.246  -0.322   0.101  -0.149  -0.305  -0.098  -0.302  -0.398
269   Q        -0.867  -0.821  -0.821  -0.859  -0.765  -0.777  -0.827  -0.765  -0.733
270   T         0.536   0.443   0.307   0.661   0.521   0.266   0.509   0.366   0.139
271   T        -0.867  -0.929  -0.837  -0.781  -0.874  -0.732  -0.827  -0.868  -0.747
272   H         0.536   0.457   0.306   0.867   0.759   0.539   0.509   0.389   0.139
273   C         0.232   0.117   0.148   0.420   0.210   0.201   0.023  -0.146  -0.126
274   M        -0.105  -0.055   0.043  -0.395  -0.353  -0.191  -0.463  -0.393  -0.272
275   M        -0.867  -0.787  -0.809  -0.738  -0.610  -0.665  -0.827  -0.730  -0.717
276   T         1.897   1.928   2.075   1.957   1.999   2.232   2.088   2.134   2.379
277   S         0.095   0.058   0.140  -0.011  -0.051   0.072  -0.220  -0.254  -0.145
278   L         1.200   1.284   1.097   0.994   1.102   0.869   1.238   1.367   1.012
279   A         1.200   1.112   1.077   1.193   1.051   0.987   1.238   1.083   0.974
280   E         1.897   1.928   2.075   1.815   1.873   2.087   2.088   2.134   2.379
281   Y         1.200   1.214   1.083   1.481   1.506   1.337   1.238   1.255   0.984
282   K         1.897   1.928   2.075   1.714   1.764   1.984   2.088   2.134   2.379
283   L         1.200   1.131   1.071   0.998   0.912   0.835   1.238   1.115   0.961
284   H         0.536   0.369   0.292   0.830   0.583   0.443   0.509   0.258   0.116
285   Q        -0.105  -0.029   0.048  -0.330  -0.180  -0.108  -0.463  -0.359  -0.265
286   E         0.232   0.189   0.185   0.128   0.093   0.051   0.023  -0.026  -0.064
287   F         0.673   0.681   0.796   0.612   0.620   0.788   0.266   0.261   0.404
288   A         1.897   1.928   2.075   1.855   1.888   2.128   2.088   2.134   2.379
289   R        -0.867  -0.934  -0.850  -0.902  -0.996  -0.897  -0.827  -0.875  -0.762
290   P         1.897   1.928   2.075   1.979   2.022   2.254   2.088   2.134   2.379
291   H         1.897   1.928   2.075   2.086   2.128   2.362   2.088   2.134   2.379
292   T         1.897   1.928   2.075   1.957   1.999   2.232   2.088   2.134   2.379
293   T         1.200   1.112   1.077   1.346   1.232   1.194   1.238   1.083   0.974
294   L        -0.089  -0.177  -0.297  -0.164  -0.283  -0.426  -0.098  -0.220  -0.366
295   Q        -0.547  -0.586  -0.470  -0.606  -0.685  -0.509  -0.706  -0.735  -0.591
296   F         0.857   0.774   0.846   0.916   0.777   0.870   0.630   0.452   0.508
297   H         0.536   0.369   0.292   0.892   0.669   0.563   0.509   0.258   0.116
298   S        -1.188  -1.204  -1.187  -1.247  -1.271  -1.210  -0.949  -0.959  -0.898
299   D         0.857   0.905   0.898   0.785   0.870   0.798   0.630   0.708   0.618
300   L         1.200   1.131   1.071   1.001   0.916   0.842   1.238   1.115   0.961
301   V        -0.347  -0.358  -0.375  -0.453  -0.514  -0.529  -0.463  -0.481  -0.479
302   K        -0.867  -0.873  -0.824  -0.902  -0.869  -0.821  -0.827  -0.813  -0.733
303   D        -0.089  -0.049  -0.241   0.032   0.074  -0.245  -0.098  -0.053  -0.294
304   K         1.897   1.928   2.075   1.714   1.764   1.984   2.088   2.134   2.379
305   G         0.095   0.163   0.146   0.052   0.137   0.151  -0.220  -0.150  -0.140
306   I        -0.867  -0.828  -0.839  -0.728  -0.681  -0.676  -0.827  -0.782  -0.752
307   V         1.200   1.112   1.077   1.324   1.219   1.169   1.238   1.083   0.974
308   F         1.200   1.314   1.105   1.001   1.143   0.894   1.238   1.414   1.026
309   M         1.200   1.214   1.083   1.414   1.437   1.219   1.238   1.255   0.984
310   N         0.536   0.369   0.292   0.743   0.525   0.394   0.509   0.258   0.116
311   G         1.200   1.112   1.077   1.445   1.344   1.322   1.238   1.083   0.974
312   H         0.536   0.625   0.359   0.744   0.866   0.524   0.509   0.635   0.221
313   V         0.536   0.440   0.318   0.726   0.609   0.427   0.509   0.362   0.157
314   E         0.536   0.457   0.306   0.619   0.537   0.321   0.509   0.389   0.139
315   P        -0.668  -0.630  -0.510  -0.961  -0.901  -0.735  -0.827  -0.779  -0.630
316   D         0.790   0.817   0.857   0.648   0.690   0.696   0.501   0.538   0.532
317   T        -0.089  -0.167  -0.285   0.062  -0.068  -0.251  -0.098  -0.209  -0.350
318   N        -0.867  -0.893  -0.856  -0.798  -0.855  -0.803  -0.827  -0.847  -0.769
319   V        -0.347  -0.367  -0.389  -0.395  -0.442  -0.484  -0.463  -0.488  -0.496
320   N        -0.089  -0.028  -0.256   0.060   0.134  -0.206  -0.098  -0.025  -0.313
321   V        -0.867  -0.898  -0.847  -0.978  -1.023  -0.908  -0.827  -0.848  -0.758
322   Q        -0.867  -0.901  -0.847  -0.793  -0.840  -0.758  -0.827  -0.851  -0.758
323   D         0.673   0.734   0.818   0.427   0.547   0.626   0.266   0.372   0.450
324   A         0.536   0.528   0.347   0.627   0.602   0.363   0.509   0.485   0.202
325   Q         1.200   1.211   1.088   1.340   1.368   1.220   1.238   1.250   0.994
326   L         0.536   0.460   0.304   0.436   0.347   0.161   0.509   0.393   0.136
327   L         1.897   1.928   2.075   1.611   1.653   1.880   2.088   2.134   2.379
328   L         0.095   0.102   0.132  -0.270  -0.245  -0.170  -0.220  -0.212  -0.158
329   L         0.536   0.457   0.306   0.412   0.315   0.118   0.509   0.389   0.139
330   N        -0.347  -0.436  -0.409  -0.220  -0.355  -0.285  -0.463  -0.571  -0.519
331   V         0.095   0.035   0.131  -0.200  -0.306  -0.172  -0.220  -0.288  -0.160
332   Q         1.897   1.928   2.075   1.935   1.989   2.210   2.088   2.134   2.379
333   R         0.536   0.443   0.307   0.691   0.549   0.310   0.509   0.366   0.139
334   F         1.897   1.928   2.075   1.986   2.036   2.261   2.088   2.134   2.379
335   Y         1.897   1.928   2.075   2.092   2.138   2.369   2.088   2.134   2.379
336   G         0.536   0.440   0.318   0.802   0.675   0.488   0.509   0.362   0.157
337   A         0.673   0.685   0.793   0.465   0.467   0.636   0.266   0.271   0.396
338   M        -1.188  -1.257  -1.216  -0.834  -0.948  -0.905  -0.949  -1.004  -0.923
339   G        -1.188  -1.257  -1.216  -0.925  -1.053  -1.007  -0.949  -1.004  -0.923
340   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
341   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
342   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
343   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
344   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
345   E        -0.563  -0.515  -0.454  -0.705  -0.623  -0.546  -0.719  -0.661  -0.569
346   E        -0.970  -1.001  -0.885  -1.001  -1.017  -0.856  -0.926  -0.940  -0.794
347   T        -0.832  -0.806  -0.831  -0.733  -0.697  -0.765  -0.768  -0.737  -0.736
348   P        -0.970  -0.950  -0.875  -0.892  -0.862  -0.760  -0.926  -0.895  -0.785
349   V        -1.418  -1.367  -1.270  -1.383  -1.352  -1.164  -1.151  -1.096  -0.967
350   A        -0.237  -0.294  -0.357  -0.146  -0.241  -0.316  -0.292  -0.367  -0.444
351   K        -0.668  -0.628  -0.761  -0.674  -0.609  -0.810  -0.584  -0.539  -0.662
352   Q        -0.547  -0.477  -0.440  -0.808  -0.665  -0.637  -0.706  -0.610  -0.555
353   R         0.536   0.597   0.341   0.734   0.819   0.450   0.509   0.596   0.193
354   V        -1.309  -1.289  -1.222  -1.353  -1.342  -1.213  -1.070  -1.037  -0.930
355   Q         0.095   0.048   0.130  -0.056  -0.124   0.004  -0.220  -0.272  -0.162
356   L         1.897   1.928   2.075   1.611   1.653   1.880   2.088   2.134   2.379
357   L         1.897   1.928   2.075   1.611   1.653   1.880   2.088   2.134   2.379
358   R        -1.630  -1.620  -1.530  -1.473  -1.462  -1.341  -1.192  -1.171  -1.044
359   D        -0.668  -0.806  -0.815  -0.443  -0.647  -0.679  -0.584  -0.734  -0.720
360   F         1.897   1.928   2.075   1.986   2.036   2.261   2.088   2.134   2.379
361   S        -0.547  -0.568  -0.456  -0.613  -0.647  -0.482  -0.706  -0.715  -0.575
362   K        -0.347  -0.292  -0.365  -0.532  -0.455  -0.556  -0.463  -0.403  -0.467
363   A         1.200   1.314   1.105   1.399   1.546   1.274   1.238   1.414   1.026
364   S         0.129   0.064   0.117   0.070  -0.013   0.039  -0.133  -0.219  -0.166
365   P        -0.547  -0.493  -0.443  -0.646  -0.575  -0.484  -0.706  -0.633  -0.558
366   G        -0.867  -0.866  -0.840  -0.756  -0.759  -0.711  -0.827  -0.822  -0.753
367   F         1.897   1.928   2.075   1.986   2.036   2.261   2.088   2.134   2.379
368   T        -0.867  -0.821  -0.821  -0.754  -0.676  -0.672  -0.827  -0.765  -0.733
369   V        -0.426  -0.429  -0.397  -0.459  -0.482  -0.409  -0.584  -0.579  -0.510
370   E        -0.426  -0.419  -0.386  -0.487  -0.455  -0.389  -0.584  -0.570  -0.499
371   K        -0.668  -0.569  -0.744  -0.759  -0.598  -0.908  -0.584  -0.467  -0.644
372   L         0.857   0.812   0.856   0.505   0.427   0.473   0.630   0.529   0.531
373   I        -0.089  -0.172  -0.281   0.170   0.045  -0.111  -0.098  -0.214  -0.345
374   S        -1.309  -1.256  -1.212  -1.386  -1.310  -1.242  -1.070  -1.013  -0.923
375   L        -0.426  -0.460  -0.396  -0.735  -0.722  -0.617  -0.584  -0.603  -0.506
376   S        -0.347  -0.351  -0.350  -0.338  -0.321  -0.309  -0.463  -0.445  -0.440
377   Q        -0.867  -0.894  -0.855  -0.862  -0.911  -0.857  -0.827  -0.848  -0.768
378   S        -0.668  -0.742  -0.781  -0.449  -0.556  -0.616  -0.584  -0.669  -0.684
379   M        -0.668  -0.707  -0.788  -0.367  -0.457  -0.600  -0.584  -0.626  -0.690
380   E        -0.237  -0.279  -0.362  -0.188  -0.245  -0.365  -0.292  -0.347  -0.449
381   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P32453
Output conservation file - output/P32453
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
