1     M         1.186   1.206   1.284   1.357   1.382   1.495   1.282   1.311   1.428
2     S        -0.373  -0.293  -0.442  -0.416  -0.281  -0.542  -0.526  -0.406  -0.608
3     S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    S        -1.602  -1.552  -1.383  -1.555  -1.498  -1.238  -1.441  -1.385  -1.166
22    K        -1.026  -1.013  -0.974  -1.029  -1.010  -0.934  -1.080  -1.055  -0.965
23    Q        -2.184  -2.117  -1.940  -2.179  -2.093  -1.824  -1.636  -1.574  -1.351
24    D        -1.026  -0.974  -0.970  -1.059  -1.050  -1.005  -1.080  -1.032  -0.962
25    K        -1.498  -1.517  -1.363  -1.358  -1.375  -1.164  -1.358  -1.358  -1.150
26    Q        -1.841  -1.807  -1.669  -1.638  -1.630  -1.381  -1.497  -1.458  -1.263
27    I        -1.841  -1.847  -1.681  -1.598  -1.574  -1.344  -1.497  -1.487  -1.272
28    E        -1.498  -1.426  -1.355  -1.358  -1.263  -1.151  -1.358  -1.280  -1.143
29    K         0.476   0.346   0.259   0.539   0.361   0.232   0.449   0.232   0.043
30    T        -1.026  -0.999  -0.965  -0.991  -0.941  -0.891  -1.080  -1.035  -0.956
31    A        -0.812  -0.925  -0.954  -0.721  -0.882  -0.878  -0.802  -0.938  -0.941
32    A        -0.193  -0.328  -0.441  -0.187  -0.383  -0.545  -0.246  -0.440  -0.601
33    Q        -1.026  -1.001  -0.976  -0.936  -0.936  -0.836  -1.080  -1.057  -0.967
34    K        -0.193  -0.204  -0.419  -0.090  -0.109  -0.422  -0.246  -0.262  -0.570
35    I        -0.469  -0.534  -0.482  -0.618  -0.716  -0.680  -0.663  -0.736  -0.664
36    S        -0.088  -0.272  -0.405   0.031  -0.239  -0.490  -0.101  -0.358  -0.550
37    K        -0.502  -0.498  -0.470  -0.586  -0.539  -0.490  -0.739  -0.699  -0.648
38    F        -0.989  -1.069  -0.967  -1.159  -1.285  -1.127  -1.058  -1.116  -0.959
39    G         0.533   0.442   0.283   0.407   0.290   0.061   0.538   0.391   0.087
40    S        -0.502  -0.502  -0.465  -0.827  -0.816  -0.750  -0.739  -0.704  -0.640
41    F         1.186   1.206   1.284   1.253   1.278   1.397   1.282   1.311   1.428
42    V        -0.989  -0.949  -0.953  -1.182  -1.136  -1.092  -1.058  -1.012  -0.946
43    A         0.533   0.442   0.283   0.500   0.380   0.144   0.538   0.391   0.087
44    G         1.186   1.206   1.284   0.981   1.008   1.142   1.282   1.311   1.428
45    G         0.533   0.552   0.294   0.388   0.412   0.030   0.538   0.563   0.107
46    L        -0.373  -0.401  -0.460  -0.570  -0.622  -0.697  -0.526  -0.579  -0.635
47    A         1.186   1.206   1.284   1.074   1.098   1.229   1.282   1.311   1.428
48    A         1.186   1.206   1.284   1.074   1.098   1.229   1.282   1.311   1.428
49    C         1.186   1.206   1.284   1.425   1.447   1.559   1.282   1.311   1.428
50    I        -0.502  -0.410  -0.459  -0.791  -0.640  -0.653  -0.739  -0.594  -0.632
51    A         1.186   1.206   1.284   1.074   1.098   1.229   1.282   1.311   1.428
52    V         1.186   1.206   1.284   1.178   1.215   1.327   1.282   1.311   1.428
53    T         1.186   1.206   1.284   1.228   1.250   1.374   1.282   1.311   1.428
54    V        -0.915  -1.037  -0.965  -0.951  -1.153  -1.078  -0.952  -1.074  -0.955
55    T         1.186   1.206   1.284   1.228   1.250   1.374   1.282   1.311   1.428
56    N         0.533   0.436   0.296   0.736   0.625   0.419   0.538   0.381   0.110
57    P         1.186   1.206   1.284   1.319   1.344   1.460   1.282   1.311   1.428
58    I         0.040   0.026   0.138  -0.156  -0.188  -0.011  -0.314  -0.354  -0.187
59    E         0.533   0.611   0.299   0.776   0.871   0.459   0.538   0.651   0.117
60    L        -0.915  -0.935  -0.940  -1.002  -1.035  -0.978  -0.952  -0.972  -0.931
61    I        -0.015   0.011   0.136  -0.306  -0.256  -0.065  -0.420  -0.382  -0.192
62    K         1.186   1.206   1.284   1.176   1.202   1.325   1.282   1.311   1.428
63    I         0.040   0.087   0.164  -0.146  -0.068   0.034  -0.314  -0.236  -0.138
64    R         1.186   1.206   1.284   1.321   1.343   1.461   1.282   1.311   1.428
65    M         0.533   0.442   0.283   0.789   0.670   0.412   0.538   0.391   0.087
66    Q         1.186   1.206   1.284   1.268   1.296   1.412   1.282   1.311   1.428
67    L         1.186   1.206   1.284   1.018   1.049   1.177   1.282   1.311   1.428
68    Q         1.186   1.206   1.284   1.268   1.296   1.412   1.282   1.311   1.428
69    G         1.186   1.206   1.284   0.981   1.008   1.142   1.282   1.311   1.428
70    E         0.533   0.442   0.283   0.758   0.643   0.388   0.538   0.391   0.087
71    M         0.533   0.665   0.308   0.467   0.624   0.190   0.538   0.729   0.133
72    S        -2.115  -2.085  -1.924  -1.827  -1.809  -1.556  -1.590  -1.555  -1.341
73    A        -0.502  -0.562  -0.485  -0.739  -0.814  -0.670  -0.739  -0.801  -0.671
74    -        -1.602  -1.560  -1.383  -1.654  -1.605  -1.331  -1.441  -1.392  -1.166
75    -        -1.121  -1.127  -0.999  -1.183  -1.185  -1.012  -1.169  -1.169  -0.990
76    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
77    S        -1.815  -1.772  -1.658  -1.565  -1.490  -1.330  -1.484  -1.437  -1.256
78    A        -0.373  -0.352  -0.459  -0.479  -0.503  -0.590  -0.526  -0.547  -0.633
79    A        -1.515  -1.420  -1.356  -1.529  -1.385  -1.271  -1.378  -1.288  -1.146
80    K        -0.915  -0.971  -0.945  -0.811  -0.878  -0.824  -0.952  -1.008  -0.935
81    V        -1.102  -1.134  -0.986  -1.301  -1.332  -1.111  -1.165  -1.182  -0.979
82    Y         1.186   1.206   1.284   1.297   1.320   1.438   1.282   1.311   1.428
83    K        -0.502  -0.530  -0.468  -0.597  -0.615  -0.503  -0.739  -0.749  -0.649
84    N        -0.373  -0.492  -0.475  -0.338  -0.540  -0.568  -0.526  -0.688  -0.654
85    P         0.533   0.442   0.283   0.742   0.621   0.353   0.538   0.391   0.087
86    I        -1.102  -1.107  -0.986  -1.337  -1.355  -1.180  -1.165  -1.152  -0.978
87    Q         0.533   0.436   0.296   0.723   0.606   0.408   0.538   0.381   0.110
88    G         0.212   0.220   0.191  -0.035  -0.034  -0.131   0.006   0.011  -0.087
89    M        -0.915  -0.884  -0.927  -0.811  -0.761  -0.867  -0.952  -0.892  -0.912
90    A        -1.102  -1.078  -0.986  -1.430  -1.368  -1.218  -1.165  -1.134  -0.979
91    V        -0.373  -0.401  -0.468  -0.471  -0.533  -0.668  -0.526  -0.576  -0.646
92    I         0.533   0.669   0.305   0.585   0.758   0.252   0.538   0.734   0.128
93    F        -0.989  -1.069  -0.967  -0.957  -1.073  -0.935  -1.058  -1.116  -0.959
94    K         0.040   0.112   0.157  -0.057   0.070   0.102  -0.314  -0.188  -0.150
95    N        -0.673  -0.739  -0.913  -0.380  -0.460  -0.747  -0.633  -0.713  -0.895
96    E         1.186   1.206   1.284   1.323   1.351   1.463   1.282   1.311   1.428
97    G         1.186   1.206   1.284   0.981   1.008   1.142   1.282   1.311   1.428
98    I         0.533   0.436   0.296   0.562   0.433   0.178   0.538   0.381   0.110
99    K        -0.989  -0.989  -0.944  -1.040  -1.056  -0.995  -1.058  -1.048  -0.937
100   G         1.186   1.206   1.284   0.981   1.008   1.142   1.282   1.311   1.428
101   L         0.533   0.436   0.296   0.438   0.314   0.099   0.538   0.381   0.110
102   Q         0.533   0.436   0.296   0.708   0.585   0.371   0.538   0.381   0.110
103   K        -1.102  -1.093  -0.995  -1.103  -1.079  -0.924  -1.165  -1.150  -0.987
104   G         1.186   1.206   1.284   0.981   1.008   1.142   1.282   1.311   1.428
105   L         0.533   0.436   0.296   0.438   0.314   0.099   0.538   0.381   0.110
106   N        -1.815  -1.675  -1.656  -1.916  -1.750  -1.639  -1.484  -1.363  -1.255
107   A        -1.102  -1.061  -0.978  -1.063  -0.958  -0.884  -1.165  -1.099  -0.969
108   A         0.212   0.238   0.196  -0.035   0.000  -0.119   0.006   0.044  -0.076
109   Y         1.186   1.206   1.284   1.297   1.320   1.438   1.282   1.311   1.428
110   I        -1.102  -1.059  -0.990  -1.219  -1.157  -1.064  -1.165  -1.121  -0.982
111   Y         1.186   1.206   1.284   1.297   1.320   1.438   1.282   1.311   1.428
112   Q         1.186   1.206   1.284   1.268   1.296   1.412   1.282   1.311   1.428
113   I         0.212   0.238   0.196   0.065   0.110  -0.025   0.006   0.044  -0.076
114   G        -0.989  -1.077  -0.954  -1.274  -1.378  -1.161  -1.058  -1.126  -0.947
115   L         1.186   1.206   1.284   1.018   1.049   1.177   1.282   1.311   1.428
116   N         1.186   1.206   1.284   1.281   1.315   1.424   1.282   1.311   1.428
117   G         1.186   1.206   1.284   0.981   1.008   1.142   1.282   1.311   1.428
118   S         0.040   0.156   0.183   0.048   0.262   0.256  -0.314  -0.107  -0.101
119   R         1.186   1.206   1.284   1.321   1.343   1.461   1.282   1.311   1.428
120   L         0.212   0.238   0.196  -0.030   0.013  -0.077   0.006   0.044  -0.076
121   G         1.186   1.206   1.284   0.981   1.008   1.142   1.282   1.311   1.428
122   F         0.212   0.235   0.183   0.154   0.184   0.024   0.006   0.038  -0.100
123   Y         1.186   1.206   1.284   1.297   1.320   1.438   1.282   1.311   1.428
124   E         1.186   1.206   1.284   1.323   1.351   1.463   1.282   1.311   1.428
125   P         1.186   1.206   1.284   1.319   1.344   1.460   1.282   1.311   1.428
126   I        -0.915  -0.968  -0.957  -0.876  -0.936  -0.907  -0.952  -1.003  -0.946
127   R         1.186   1.206   1.284   1.321   1.343   1.461   1.282   1.311   1.428
128   S        -2.416  -2.344  -2.161  -2.155  -2.000  -1.801  -1.697  -1.635  -1.409
129   S        -2.115  -2.085  -1.926  -1.957  -1.933  -1.691  -1.590  -1.555  -1.343
130   L        -0.088   0.038  -0.375  -0.102   0.054  -0.484  -0.101   0.066  -0.508
131   N        -0.915  -0.923  -0.955  -0.860  -0.904  -0.954  -0.952  -0.967  -0.946
132   Q        -1.102  -1.029  -0.985  -1.128  -1.049  -0.935  -1.165  -1.098  -0.978
133   L        -1.815  -1.771  -1.658  -1.744  -1.642  -1.519  -1.484  -1.437  -1.256
134   F        -0.373  -0.404  -0.461  -0.350  -0.429  -0.503  -0.526  -0.581  -0.636
135   F        -1.815  -1.809  -1.664  -1.705  -1.726  -1.521  -1.484  -1.460  -1.260
136   P        -0.673  -0.833  -0.925  -0.333  -0.553  -0.718  -0.633  -0.827  -0.909
137   D        -0.373  -0.299  -0.452  -0.178  -0.078  -0.328  -0.526  -0.431  -0.621
138   Q        -2.115  -2.118  -1.937  -1.893  -1.918  -1.665  -1.590  -1.575  -1.349
139   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
140   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
141   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
142   E        -0.460  -0.517  -0.512  -0.376  -0.484  -0.531  -0.624  -0.708  -0.701
143   P        -1.121  -1.113  -1.001  -1.171  -1.176  -1.001  -1.169  -1.155  -0.992
144   H        -0.966  -1.034  -0.992  -0.708  -0.827  -0.826  -0.987  -1.064  -0.982
145   K         0.212   0.238   0.196   0.129   0.168   0.064   0.006   0.044  -0.076
146   V        -1.702  -1.780  -1.668  -1.536  -1.685  -1.506  -1.378  -1.435  -1.262
147   Q         0.212   0.170   0.170   0.252   0.180   0.143   0.006  -0.079  -0.126
148   S        -1.402  -1.415  -1.343  -1.219  -1.245  -1.103  -1.271  -1.277  -1.134
149   V        -0.502  -0.387  -0.467  -0.793  -0.612  -0.704  -0.739  -0.577  -0.645
150   G        -0.673  -0.734  -0.918  -0.683  -0.781  -0.999  -0.633  -0.707  -0.901
151   V        -0.088   0.034  -0.370  -0.012   0.153  -0.469  -0.101   0.062  -0.502
152   N         1.186   1.206   1.284   1.281   1.315   1.424   1.282   1.311   1.428
153   V         0.533   0.436   0.296   0.626   0.517   0.313   0.538   0.381   0.110
154   F        -0.688  -0.656  -0.523  -1.019  -0.980  -0.774  -0.952  -0.907  -0.716
155   S         0.040   0.059   0.143  -0.261  -0.238  -0.102  -0.314  -0.290  -0.179
156   G         1.186   1.206   1.284   0.981   1.008   1.142   1.282   1.311   1.428
157   A         0.212   0.238   0.196   0.055   0.089   0.016   0.006   0.044  -0.076
158   A        -1.215  -1.226  -1.315  -1.216  -1.261  -1.411  -1.058  -1.067  -1.106
159   S         1.186   1.206   1.284   1.203   1.232   1.350   1.282   1.311   1.428
160   G         1.186   1.206   1.284   0.981   1.008   1.142   1.282   1.311   1.428
161   I        -0.915  -0.924  -0.955  -1.026  -1.051  -1.127  -0.952  -0.957  -0.945
162   I        -1.815  -1.775  -1.665  -1.615  -1.509  -1.395  -1.484  -1.434  -1.260
163   G         1.186   1.206   1.284   0.981   1.008   1.142   1.282   1.311   1.428
164   A         1.186   1.206   1.284   1.074   1.098   1.229   1.282   1.311   1.428
165   V        -0.673  -0.787  -0.911  -0.510  -0.678  -0.879  -0.633  -0.776  -0.893
166   I        -1.515  -1.460  -1.363  -1.675  -1.613  -1.395  -1.378  -1.319  -1.150
167   G         0.212   0.238   0.196  -0.096  -0.060  -0.153   0.006   0.044  -0.076
168   S         1.186   1.206   1.284   1.203   1.232   1.350   1.282   1.311   1.428
169   P         1.186   1.206   1.284   1.319   1.344   1.460   1.282   1.311   1.428
170   L        -0.502  -0.410  -0.459  -0.653  -0.461  -0.517  -0.739  -0.594  -0.632
171   F         0.533   0.552   0.294   0.692   0.715   0.354   0.538   0.563   0.107
172   L         1.186   1.206   1.284   1.018   1.049   1.177   1.282   1.311   1.428
173   V        -0.502  -0.555  -0.483  -0.687  -0.754  -0.656  -0.739  -0.789  -0.669
174   K         1.186   1.206   1.284   1.176   1.202   1.325   1.282   1.311   1.428
175   T         1.186   1.206   1.284   1.228   1.250   1.374   1.282   1.311   1.428
176   R         1.186   1.206   1.284   1.321   1.343   1.461   1.282   1.311   1.428
177   L        -0.502  -0.464  -0.469  -0.584  -0.511  -0.502  -0.739  -0.682  -0.648
178   Q         1.186   1.206   1.284   1.268   1.296   1.412   1.282   1.311   1.428
179   S         1.186   1.206   1.284   1.203   1.232   1.350   1.282   1.311   1.428
180   Y         0.533   0.558   0.296   0.730   0.758   0.381   0.538   0.572   0.110
181   S         1.186   1.206   1.284   1.203   1.232   1.350   1.282   1.311   1.428
182   E        -1.402  -1.250  -1.329  -1.262  -1.031  -1.196  -1.271  -1.106  -1.121
183   F        -0.915  -0.970  -0.945  -0.981  -1.068  -1.007  -0.952  -1.008  -0.935
184   I        -1.402  -1.440  -1.354  -1.383  -1.450  -1.318  -1.271  -1.296  -1.143
185   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
186   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
187   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
188   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
189   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
190   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
191   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
192   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
193   K        -1.402  -1.363  -1.346  -1.337  -1.285  -1.262  -1.271  -1.233  -1.137
194   I         0.040   0.156   0.183  -0.191   0.030   0.033  -0.314  -0.107  -0.101
195   G         1.186   1.206   1.284   0.981   1.008   1.142   1.282   1.311   1.428
196   E        -0.915  -0.884  -0.927  -0.790  -0.733  -0.832  -0.952  -0.892  -0.912
197   Q         1.186   1.206   1.284   1.268   1.296   1.412   1.282   1.311   1.428
198   T        -0.088  -0.272  -0.405   0.137  -0.107  -0.289  -0.101  -0.358  -0.550
199   H        -1.402  -1.481  -1.356  -1.156  -1.311  -1.147  -1.271  -1.328  -1.144
200   Y         1.186   1.206   1.284   1.297   1.320   1.438   1.282   1.311   1.428
201   T         0.040   0.156   0.183  -0.158   0.039   0.065  -0.314  -0.107  -0.101
202   G        -1.102  -1.134  -0.989  -1.252  -1.245  -1.010  -1.165  -1.183  -0.982
203   V        -1.515  -1.460  -1.357  -1.632  -1.549  -1.377  -1.378  -1.314  -1.146
204   W        -0.915  -0.910  -0.948  -0.700  -0.713  -0.851  -0.952  -0.947  -0.939
205   N        -0.015   0.017   0.137  -0.063  -0.005   0.169  -0.420  -0.372  -0.190
206   G         0.533   0.442   0.283   0.388   0.263   0.011   0.538   0.391   0.087
207   L         0.040   0.037   0.138  -0.283  -0.290  -0.115  -0.314  -0.331  -0.189
208   V        -2.115  -2.006  -1.918  -2.025  -1.851  -1.755  -1.590  -1.498  -1.337
209   T        -1.102  -1.140  -0.993  -1.108  -1.164  -0.929  -1.165  -1.190  -0.985
210   I         1.186   1.206   1.284   1.162   1.196   1.312   1.282   1.311   1.428
211   F        -0.373  -0.360  -0.440  -0.272  -0.238  -0.399  -0.526  -0.485  -0.603
212   K        -1.215  -1.062  -1.289  -0.987  -0.794  -1.090  -1.058  -0.890  -1.081
213   T        -1.515  -1.540  -1.361  -1.612  -1.661  -1.382  -1.378  -1.376  -1.149
214   E         0.533   0.442   0.283   0.760   0.646   0.393   0.538   0.391   0.087
215   G         1.186   1.206   1.284   0.981   1.008   1.142   1.282   1.311   1.428
216   V        -0.502  -0.468  -0.479  -0.650  -0.583  -0.581  -0.739  -0.688  -0.663
217   K         0.533   0.558   0.298   0.598   0.632   0.252   0.538   0.572   0.115
218   G         1.186   1.206   1.284   0.981   1.008   1.142   1.282   1.311   1.428
219   L         1.186   1.206   1.284   1.018   1.049   1.177   1.282   1.311   1.428
220   F         0.040   0.036   0.140  -0.054  -0.076   0.084  -0.314  -0.334  -0.184
221   R         0.533   0.442   0.283   0.744   0.620   0.354   0.538   0.391   0.087
222   G         1.186   1.206   1.284   0.981   1.008   1.142   1.282   1.311   1.428
223   I        -0.373  -0.328  -0.429  -0.436  -0.336  -0.547  -0.526  -0.439  -0.586
224   D         0.533   0.436   0.296   0.790   0.650   0.376   0.538   0.381   0.110
225   A         1.186   1.206   1.284   1.074   1.098   1.229   1.282   1.311   1.428
226   A         1.186   1.206   1.284   1.074   1.098   1.229   1.282   1.311   1.428
227   I         0.212   0.195   0.181   0.175   0.150   0.116   0.006  -0.035  -0.106
228   L         0.533   0.436   0.296   0.438   0.314   0.099   0.538   0.381   0.110
229   R         1.186   1.206   1.284   1.321   1.343   1.461   1.282   1.311   1.428
230   T         1.186   1.206   1.284   1.228   1.250   1.374   1.282   1.311   1.428
231   G         0.533   0.442   0.283   0.403   0.286   0.051   0.538   0.391   0.087
232   A        -0.673  -0.787  -0.911  -0.617  -0.786  -0.967  -0.633  -0.776  -0.893
233   G         1.186   1.206   1.284   0.981   1.008   1.142   1.282   1.311   1.428
234   S         1.186   1.206   1.284   1.203   1.232   1.350   1.282   1.311   1.428
235   S         0.040   0.081   0.147  -0.215  -0.144  -0.073  -0.314  -0.247  -0.170
236   V         0.212   0.238   0.196   0.098   0.144   0.016   0.006   0.044  -0.076
237   Q         1.186   1.206   1.284   1.268   1.296   1.412   1.282   1.311   1.428
238   L         1.186   1.206   1.284   1.018   1.049   1.177   1.282   1.311   1.428
239   P         1.186   1.206   1.284   1.319   1.344   1.460   1.282   1.311   1.428
240   I        -0.373  -0.399  -0.465  -0.406  -0.455  -0.557  -0.526  -0.575  -0.642
241   Y         1.186   1.206   1.284   1.297   1.320   1.438   1.282   1.311   1.428
242   N        -0.088  -0.170  -0.388   0.165   0.058  -0.273  -0.101  -0.219  -0.526
243   T        -1.515  -1.437  -1.356  -1.384  -1.255  -1.171  -1.378  -1.298  -1.145
244   A        -0.373  -0.299  -0.452  -0.441  -0.353  -0.509  -0.526  -0.431  -0.621
245   K         1.186   1.206   1.284   1.176   1.202   1.325   1.282   1.311   1.428
246   N        -1.102  -1.093  -0.995  -1.028  -1.013  -0.855  -1.165  -1.150  -0.987
247   I        -1.402  -1.427  -1.340  -1.334  -1.365  -1.229  -1.271  -1.287  -1.132
248   L         0.533   0.442   0.283   0.438   0.323   0.078   0.538   0.391   0.087
249   V        -0.373  -0.451  -0.457  -0.534  -0.629  -0.627  -0.526  -0.624  -0.630
250   K        -0.673  -0.644  -0.894  -0.430  -0.399  -0.705  -0.633  -0.605  -0.873
251   N        -0.615  -0.537  -0.492  -0.505  -0.389  -0.351  -0.846  -0.745  -0.676
252   D        -1.215  -1.339  -1.330  -0.869  -1.088  -1.140  -1.058  -1.183  -1.120
253   L        -0.502  -0.540  -0.469  -0.843  -0.892  -0.782  -0.739  -0.765  -0.651
254   M        -1.215  -1.262  -1.328  -0.949  -1.050  -1.238  -1.058  -1.103  -1.118
255   K        -0.915  -0.806  -0.928  -0.724  -0.553  -0.738  -0.952  -0.813  -0.917
256   D        -0.502  -0.491  -0.480  -0.366  -0.365  -0.322  -0.739  -0.728  -0.665
257   G         0.212   0.238   0.196  -0.025   0.014  -0.047   0.006   0.044  -0.076
258   P        -1.402  -1.400  -1.350  -1.231  -1.230  -1.172  -1.271  -1.260  -1.140
259   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
260   A        -1.102  -1.124  -0.981  -1.372  -1.403  -1.193  -1.165  -1.171  -0.973
261   L        -0.088  -0.170  -0.405  -0.123  -0.235  -0.576  -0.101  -0.218  -0.551
262   H         0.533   0.558   0.296   0.838   0.871   0.483   0.538   0.572   0.110
263   L         0.212   0.238   0.196   0.001   0.041  -0.031   0.006   0.044  -0.076
264   T        -1.402  -1.422  -1.342  -1.479  -1.520  -1.421  -1.271  -1.275  -1.133
265   A        -0.015   0.013   0.136  -0.352  -0.306  -0.106  -0.420  -0.379  -0.192
266   S         0.533   0.558   0.298   0.598   0.634   0.208   0.538   0.572   0.115
267   T        -0.502  -0.486  -0.481  -0.682  -0.682  -0.646  -0.739  -0.721  -0.666
268   I        -1.402  -1.481  -1.355  -1.381  -1.504  -1.339  -1.271  -1.328  -1.144
269   S         0.040   0.081   0.147  -0.215  -0.144  -0.073  -0.314  -0.247  -0.170
270   G         1.186   1.206   1.284   0.981   1.008   1.142   1.282   1.311   1.428
271   L         0.040   0.026   0.138  -0.283  -0.308  -0.115  -0.314  -0.354  -0.187
272   G         0.533   0.436   0.296   0.403   0.278   0.072   0.538   0.381   0.110
273   V         1.186   1.206   1.284   1.178   1.215   1.327   1.282   1.311   1.428
274   A        -0.373  -0.397  -0.465  -0.448  -0.492  -0.583  -0.526  -0.596  -0.642
275   V        -0.373  -0.437  -0.465  -0.368  -0.432  -0.480  -0.526  -0.602  -0.638
276   V        -0.088  -0.117  -0.395   0.021  -0.013  -0.460  -0.101  -0.148  -0.536
277   M         1.186   1.206   1.284   1.357   1.382   1.495   1.282   1.311   1.428
278   N        -0.088  -0.272  -0.405   0.184  -0.050  -0.257  -0.101  -0.358  -0.550
279   P         0.533   0.442   0.283   0.740   0.617   0.347   0.538   0.391   0.087
280   W        -0.088  -0.272  -0.405   0.345   0.090  -0.147  -0.101  -0.358  -0.550
281   D         1.186   1.206   1.284   1.394   1.421   1.530   1.282   1.311   1.428
282   V         0.212   0.118   0.168   0.148  -0.017   0.039   0.006  -0.178  -0.129
283   I        -0.502  -0.485  -0.476  -0.702  -0.671  -0.664  -0.739  -0.718  -0.660
284   L         0.040   0.019   0.137  -0.225  -0.244  -0.044  -0.314  -0.367  -0.191
285   T         0.533   0.436   0.296   0.654   0.522   0.303   0.538   0.381   0.110
286   R         1.186   1.206   1.284   1.321   1.343   1.461   1.282   1.311   1.428
287   I        -1.102  -1.063  -0.969  -1.137  -1.050  -0.960  -1.165  -1.100  -0.960
288   Y         1.186   1.206   1.284   1.297   1.320   1.438   1.282   1.311   1.428
289   N         1.186   1.206   1.284   1.281   1.315   1.424   1.282   1.311   1.428
290   Q         1.186   1.206   1.284   1.268   1.296   1.412   1.282   1.311   1.428
291   K         0.533   0.436   0.296   0.613   0.491   0.284   0.538   0.381   0.110
292   G         0.533   0.442   0.283   0.419   0.307   0.092   0.538   0.391   0.087
293   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
294   D        -0.502  -0.512  -0.467  -0.411  -0.399  -0.332  -0.739  -0.722  -0.645
295   L         0.533   0.552   0.294   0.467   0.496   0.169   0.538   0.563   0.107
296   Y         1.186   1.206   1.284   1.297   1.320   1.438   1.282   1.311   1.428
297   K         0.212   0.268   0.189   0.138   0.223   0.064   0.006   0.097  -0.089
298   G         0.212   0.170   0.170  -0.025  -0.092  -0.086   0.006  -0.079  -0.126
299   P         0.533   0.436   0.296   0.742   0.612   0.375   0.538   0.381   0.110
300   I         0.212   0.167   0.177   0.141   0.065   0.056   0.006  -0.085  -0.112
301   D         1.186   1.206   1.284   1.394   1.421   1.530   1.282   1.311   1.428
302   C         1.186   1.206   1.284   1.425   1.447   1.559   1.282   1.311   1.428
303   L        -0.502  -0.544  -0.484  -0.744  -0.791  -0.676  -0.739  -0.773  -0.669
304   V        -2.115  -2.118  -1.937  -2.047  -2.093  -1.807  -1.590  -1.575  -1.349
305   K         1.186   1.206   1.284   1.176   1.202   1.325   1.282   1.311   1.428
306   T         1.186   1.206   1.284   1.228   1.250   1.374   1.282   1.311   1.428
307   V         0.040   0.020   0.137  -0.191  -0.237  -0.062  -0.314  -0.366  -0.191
308   R        -0.673  -0.553  -0.885  -0.404  -0.247  -0.784  -0.633  -0.486  -0.863
309   I        -1.402  -1.412  -1.345  -1.418  -1.455  -1.318  -1.271  -1.274  -1.136
310   E         1.186   1.206   1.284   1.323   1.351   1.463   1.282   1.311   1.428
311   G         1.186   1.206   1.284   0.981   1.008   1.142   1.282   1.311   1.428
312   V        -1.702  -1.496  -1.625  -1.552  -1.228  -1.496  -1.378  -1.180  -1.229
313   T        -1.102  -0.988  -0.971  -1.087  -0.903  -0.872  -1.165  -1.023  -0.962
314   A         1.186   1.206   1.284   1.074   1.098   1.229   1.282   1.311   1.428
315   L         0.533   0.436   0.296   0.438   0.314   0.099   0.538   0.381   0.110
316   Y         1.186   1.206   1.284   1.297   1.320   1.438   1.282   1.311   1.428
317   K         1.186   1.206   1.284   1.176   1.202   1.325   1.282   1.311   1.428
318   G         1.186   1.206   1.284   0.981   1.008   1.142   1.282   1.311   1.428
319   F         0.533   0.436   0.296   0.675   0.546   0.316   0.538   0.381   0.110
320   A        -1.702  -1.600  -1.632  -1.623  -1.499  -1.475  -1.378  -1.283  -1.235
321   A         0.533   0.436   0.296   0.517   0.394   0.207   0.538   0.381   0.110
322   Q         0.040   0.019   0.137   0.014  -0.023   0.157  -0.314  -0.367  -0.191
323   V        -0.373  -0.182  -0.419  -0.567  -0.269  -0.625  -0.526  -0.246  -0.572
324   F        -0.915  -1.024  -0.958  -0.941  -1.115  -1.058  -0.952  -1.057  -0.949
325   R         1.186   1.206   1.284   1.321   1.343   1.461   1.282   1.311   1.428
326   I         1.186   1.206   1.284   1.162   1.196   1.312   1.282   1.311   1.428
327   A        -0.989  -1.016  -0.952  -1.264  -1.301  -1.139  -1.058  -1.070  -0.945
328   P         1.186   1.206   1.284   1.319   1.344   1.460   1.282   1.311   1.428
329   H         1.186   1.206   1.284   1.401   1.428   1.537   1.282   1.311   1.428
330   T         0.533   0.558   0.298   0.654   0.682   0.307   0.538   0.572   0.115
331   I         0.533   0.611   0.299   0.585   0.691   0.241   0.538   0.651   0.117
332   M        -0.088  -0.068  -0.383  -0.086  -0.072  -0.463  -0.101  -0.086  -0.520
333   C        -0.015   0.017   0.137  -0.078  -0.049   0.146  -0.420  -0.372  -0.190
334   L         1.186   1.206   1.284   1.018   1.049   1.177   1.282   1.311   1.428
335   T        -0.915  -0.966  -0.956  -0.828  -0.910  -0.914  -0.952  -1.001  -0.946
336   F         0.533   0.436   0.296   0.653   0.515   0.261   0.538   0.381   0.110
337   M        -0.673  -0.741  -0.902  -0.404  -0.527  -0.853  -0.633  -0.727  -0.882
338   E         1.186   1.206   1.284   1.323   1.351   1.463   1.282   1.311   1.428
339   Q         0.533   0.558   0.298   0.723   0.757   0.412   0.538   0.572   0.115
340   T         0.212   0.238   0.196   0.260   0.290   0.227   0.006   0.044  -0.076
341   M        -0.673  -0.787  -0.911  -0.355  -0.526  -0.777  -0.633  -0.776  -0.893
342   K         0.533   0.558   0.298   0.613   0.646   0.289   0.538   0.572   0.115
343   L        -0.673  -0.646  -0.908  -0.692  -0.651  -1.044  -0.633  -0.596  -0.889
344   V        -0.373  -0.437  -0.465  -0.327  -0.403  -0.449  -0.526  -0.602  -0.638
345   Y        -1.815  -1.758  -1.663  -1.632  -1.601  -1.415  -1.484  -1.424  -1.259
346   S        -0.989  -0.877  -0.945  -1.010  -0.855  -0.904  -1.058  -0.937  -0.938
347   I        -0.989  -0.989  -0.950  -1.067  -1.072  -1.011  -1.058  -1.048  -0.943
348   E         0.533   0.442   0.283   0.758   0.643   0.388   0.538   0.391   0.087
349   S        -1.402  -1.442  -1.351  -1.329  -1.383  -1.244  -1.271  -1.298  -1.140
350   R        -0.915  -0.905  -0.940  -0.812  -0.779  -0.821  -0.952  -0.920  -0.927
351   V        -1.498  -1.501  -1.371  -1.584  -1.591  -1.355  -1.358  -1.345  -1.156
352   L        -0.812  -0.828  -0.951  -0.769  -0.796  -0.905  -0.802  -0.818  -0.938
353   G         0.020   0.045   0.142  -0.386  -0.355  -0.181  -0.352  -0.317  -0.181
354   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
355   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
356   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
357   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
358   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
359   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P32332
Output conservation file - output/P32332
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
